Basic Information
Locus ID:
jg18682
Species & Taxonomic ID:
Avicennia marina & 1381980
Genome Assembly:
GCA_013168755.1
Description:
ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail- anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the membrane-bound receptor, and returning it to the cytosol to initiate a new round of targeting
Maps and Mapping Data
| Chromosome | Start | End | Strand | ID |
|---|---|---|---|---|
| chr27 | 10036448 | 10037746 | + | jg18682 |
Protein Data
Protein Properties:
| Theoretical pI | Molecular Weight | Instability Index | Aliphatic Index | GRAVY |
|---|---|---|---|---|
| 5.20 | 48,734.51 Da | 53.22 | 74.07 | -0.54 |
Protein Domain:
| Category | ID | Description | Start | End | Evalue/Score | InterPro ID |
|---|---|---|---|---|---|---|
| Pfam | PF00069 | Protein kinase domain | 142 | 413 | 1.6E-18 | IPR000719 |
| SUPERFAMILY | SSF56112 | Protein kinase-like (PK-like) | 131 | 412 | 3.42E-29 | IPR011009 |
| Gene3D | G3DSA:1.10.510.10 | Transferase(Phosphotransferase) domain 1 | 120 | 424 | 2.0E-27 | - |
| SMART | SM00220 | serkin_6 | 104 | 413 | 1.3E-9 | IPR000719 |
| ProSiteProfiles | PS50011 | Protein kinase domain profile. | 104 | 413 | 22.251875 | IPR000719 |
| MobiDBLite | mobidb-lite | consensus disorder prediction | 10 | 29 | - | - |
| MobiDBLite | mobidb-lite | consensus disorder prediction | 1 | 33 | - | - |
Gene Ontology
Biological Process:
Molecular Function:
KEGG Pathway
Best hit
| Source | Best Hit ID | Description | E-value |
|---|---|---|---|
| RefSeq | XP_011094629.1 | serine/threonine-protein kinase BLUS1-like [Sesamum indicum] | 0 |
| Q5R495 | Serine/threonine-protein kinase OSR1 OS=Pongo abelii OX=9601 GN=OXSR1 PE=2 SV=1 | 0 | |
| TrEMBL | A0A6I9UJT8 | serine/threonine-protein kinase BLUS1-like OS=Sesamum indicum OX=4182 GN=LOC105174279 PE=4 SV=1 | 0 |
Expression
| BioProject | Accession | TPM | Cultivar | Tissue | Development Stage | Sample Name | Description |
|---|---|---|---|---|---|---|---|
| No sample metadata found. | |||||||
Orthology
| Family | Species | Count | Orthologous Genes |
|---|---|---|---|
| Acanthaceae | Avicennia marina | 3 | jg18682, jg1869, jg8331 |
| Anacardiaceae | Pistacia vera | 1 | pistato.v30003640 |
| Apiaceae | Apium graveolens | 2 | Ag2G02557, AgUnG00499 |
| Solanaceae | Lycium barbarum | 5 | gene-LOC132613084, gene-LOC132613089, gene-LOC132613094 ... |
| Solanaceae | Solanum chilense | 5 | SOLCI000552200, SOLCI001268300, SOLCI001371800 ... |
| Solanaceae | Solanum pennellii | 7 | gene-LOC107019742, gene-LOC107032678, gene-LOC107032679 ... |