Basic Information
Locus ID:
gene_18059
Species & Taxonomic ID:
Mesembryanthemum crystallinum & 3544
Genome Assembly:
Koichi Toyokura Assembly
Description:
Belongs to the short-chain dehydrogenases reductases (SDR) family
Maps and Mapping Data
| Chromosome | Start | End | Strand | ID |
|---|---|---|---|---|
| Super-Scaffold_10_Chr_8 | 1673242 | 1687160 | + | gene_18059 |
Protein Data
Protein Properties:
| Theoretical pI | Molecular Weight | Instability Index | Aliphatic Index | GRAVY |
|---|---|---|---|---|
| 9.02 | 52,123.14 Da | 43.67 | 106.21 | 0.09 |
Protein Domain:
| Category | ID | Description | Start | End | Evalue/Score | InterPro ID |
|---|---|---|---|---|---|---|
| CDD | cd05356 | 17beta-HSD1_like_SDR_c | 105 | 324 | 2.93182E-91 | - |
| Pfam | PF00069 | Protein kinase domain | 422 | 460 | 6.6E-10 | IPR000719 |
| Pfam | PF00106 | short chain dehydrogenase | 107 | 301 | 2.9E-39 | IPR002347 |
| SUPERFAMILY | SSF56112 | Protein kinase-like (PK-like) | 422 | 464 | 1.62E-14 | IPR011009 |
| SUPERFAMILY | SSF51735 | NAD(P)-binding Rossmann-fold domains | 105 | 321 | 4.33E-49 | IPR036291 |
| Gene3D | G3DSA:3.40.50.720 | - | 99 | 328 | 6.1E-50 | - |
| Gene3D | G3DSA:1.10.510.10 | Transferase(Phosphotransferase) domain 1 | 405 | 467 | 3.3E-14 | - |
| ProSiteProfiles | PS50011 | Protein kinase domain profile. | 230 | 467 | 10.859873 | IPR000719 |
| ProSitePatterns | PS00061 | Short-chain dehydrogenases/reductases family signature. | 248 | 276 | - | IPR020904 |
| ProSitePatterns | PS00108 | Serine/Threonine protein kinases active-site signature. | 429 | 441 | - | IPR008271 |
| PRINTS | PR00080 | Short-chain dehydrogenase/reductase (SDR) superfamily signature | 239 | 247 | 2.4E-5 | IPR002347 |
| PRINTS | PR00080 | Short-chain dehydrogenase/reductase (SDR) superfamily signature | 261 | 280 | 2.4E-5 | IPR002347 |
| PRINTS | PR00081 | Glucose/ribitol dehydrogenase family signature | 261 | 280 | 2.8E-17 | IPR002347 |
| PRINTS | PR00081 | Glucose/ribitol dehydrogenase family signature | 233 | 249 | 2.8E-17 | IPR002347 |
| PRINTS | PR00081 | Glucose/ribitol dehydrogenase family signature | 184 | 195 | 2.8E-17 | IPR002347 |
| PRINTS | PR00081 | Glucose/ribitol dehydrogenase family signature | 107 | 124 | 2.8E-17 | IPR002347 |
| PRINTS | PR00081 | Glucose/ribitol dehydrogenase family signature | 282 | 299 | 2.8E-17 | IPR002347 |
| PRINTS | PR00080 | Short-chain dehydrogenase/reductase (SDR) superfamily signature | 184 | 195 | 2.4E-5 | IPR002347 |
Gene Ontology
Biological Process:
KEGG Pathway
Pathway:
ko00062 (Fatty acid elongation)
map00062 (Fatty acid elongation)
ko00140 (Steroid hormone biosynthesis)
map00140 (Steroid hormone biosynthesis)
ko01040 (Biosynthesis of unsaturated fatty acids)
map01040 (Biosynthesis of unsaturated fatty acids)
ko01100 (Metabolic pathways)
map01100 (Metabolic pathways)
ko01110 (Biosynthesis of secondary metabolites)
map01110 (Biosynthesis of secondary metabolites)
ko01212 (Fatty acid metabolism)
map01212 (Fatty acid metabolism)
Reaction:
R02352 (Estradiol-17beta + NAD+ <=> Estrone + NADH + H+)
R02353 (Estradiol-17beta + NADP+ <=> Estrone + NADPH + H+)
R04681 (Estriol + NAD+ <=> 16alpha-Hydroxyestrone + NADH + H+)
R04682 (Estriol + NADP+ <=> 16alpha-Hydroxyestrone + NADPH + H+)
R07759 (3-Oxostearoyl-CoA + NADPH + H+ <=> 3-Hydroxyoctadecanoyl-CoA + NADP+)
R08945 (11beta,17beta-Dihydroxy-4-androsten-3-one + NAD+ <=> 11beta-Hydroxyandrost-4-ene-3,17-dione + NADH + H+)
R08980 (11beta,17beta-Dihydroxy-4-androsten-3-one + NADP+ <=> 11beta-Hydroxyandrost-4-ene-3,17-dione + NADPH + H+)
R10826 (Very-long-chain (3R)-3-hydroxyacyl-CoA + NADP+ <=> Very-long-chain 3-oxoacyl-CoA + NADPH + H+)
Best hit
| Source | Best Hit ID | Description | E-value |
|---|---|---|---|
| TAIR | AT1G24470.1 | beta-ketoacyl reductase 2. Encodes one of the two Arabidopsis homologues to YBR159w encoding a S. cerevisiae beta-ketoacyl reductase (KCR), which catalyzes the first reduction during VLCFA (very long chain fatty acids, >18 carbon) elongation: KCR1 (At1g67730), KCR2 (At1g24470). Complementation of the yeast ybr159Delta mutant demonstrated that the two KCR proteins are divergent and that only AtKCR1 can restore heterologous elongase activity similar to the native yeast KCR gene. | 0 |
| RefSeq | XP_041013935.1 | very-long-chain 3-oxoacyl-CoA reductase-like protein At1g24470 [Juglans microcarpa x Juglans regia] | 0 |
| Q9FYL6 | Very-long-chain 3-oxoacyl-CoA reductase-like protein At1g24470 OS=Arabidopsis thaliana OX=3702 GN=KCR2 PE=2 SV=1 | 0 | |
| TrEMBL | A0A8J4R3D5 | Very-long-chain 3-oxoacyl-CoA reductase 1-like OS=Castanea mollissima OX=60419 GN=CMV_019241 PE=3 SV=1 | 0 |
Expression
| BioProject | Accession | TPM | Cultivar | Tissue | Development Stage | Sample Name | Description |
|---|---|---|---|---|---|---|---|
| No sample metadata found. | |||||||
Network
No network data available for this species.
Orthology