Basic Information
Locus ID:
gene-LOC132621672
Species & Taxonomic ID:
Lycium barbarum & 112863
Genome Assembly:
GCF_019175385.1
Description:
Belongs to the short-chain dehydrogenases reductases (SDR) family
Maps and Mapping Data
| Chromosome | Start | End | Strand | ID |
|---|---|---|---|---|
| chr12 | 105158704 | 105162439 | - | gene-LOC132621672 |
Protein Data
Protein Properties:
| Theoretical pI | Molecular Weight | Instability Index | Aliphatic Index | GRAVY |
|---|---|---|---|---|
| 9.53 | 35,747.64 Da | 19.88 | 108.41 | 0.10 |
Protein Domain:
| Category | ID | Description | Start | End | Evalue/Score | InterPro ID |
|---|---|---|---|---|---|---|
| CDD | cd05356 | 17beta-HSD1_like_SDR_c | 53 | 295 | 2.48871E-119 | - |
| Pfam | PF00106 | short chain dehydrogenase | 55 | 247 | 7.6E-41 | IPR002347 |
| SUPERFAMILY | SSF51735 | NAD(P)-binding Rossmann-fold domains | 53 | 311 | 2.77E-49 | IPR036291 |
| Gene3D | G3DSA:3.40.50.720 | - | 48 | 272 | 2.2E-50 | - |
| PIRSF | PIRSF000126 | 11-beta-HSD1 | 5 | 314 | 1.9E-101 | - |
| PRINTS | PR00081 | Glucose/ribitol dehydrogenase family signature | 55 | 72 | 4.8E-17 | IPR002347 |
| PRINTS | PR00081 | Glucose/ribitol dehydrogenase family signature | 229 | 246 | 4.8E-17 | IPR002347 |
| PRINTS | PR00081 | Glucose/ribitol dehydrogenase family signature | 131 | 142 | 4.8E-17 | IPR002347 |
| PRINTS | PR00081 | Glucose/ribitol dehydrogenase family signature | 208 | 227 | 4.8E-17 | IPR002347 |
| PRINTS | PR00080 | Short-chain dehydrogenase/reductase (SDR) superfamily signature | 131 | 142 | 5.6E-6 | IPR002347 |
| PRINTS | PR00080 | Short-chain dehydrogenase/reductase (SDR) superfamily signature | 208 | 227 | 5.6E-6 | IPR002347 |
| PRINTS | PR00080 | Short-chain dehydrogenase/reductase (SDR) superfamily signature | 186 | 194 | 5.6E-6 | IPR002347 |
| PRINTS | PR00081 | Glucose/ribitol dehydrogenase family signature | 180 | 196 | 4.8E-17 | IPR002347 |
Gene Ontology
Molecular Function:
KEGG Pathway
Pathway:
ko00062 (Fatty acid elongation)
map00062 (Fatty acid elongation)
ko00140 (Steroid hormone biosynthesis)
map00140 (Steroid hormone biosynthesis)
ko01040 (Biosynthesis of unsaturated fatty acids)
map01040 (Biosynthesis of unsaturated fatty acids)
ko01100 (Metabolic pathways)
map01100 (Metabolic pathways)
ko01110 (Biosynthesis of secondary metabolites)
map01110 (Biosynthesis of secondary metabolites)
ko01212 (Fatty acid metabolism)
map01212 (Fatty acid metabolism)
Reaction:
R02352 (Estradiol-17beta + NAD+ <=> Estrone + NADH + H+)
R02353 (Estradiol-17beta + NADP+ <=> Estrone + NADPH + H+)
R04681 (Estriol + NAD+ <=> 16alpha-Hydroxyestrone + NADH + H+)
R04682 (Estriol + NADP+ <=> 16alpha-Hydroxyestrone + NADPH + H+)
R07759 (3-Oxostearoyl-CoA + NADPH + H+ <=> 3-Hydroxyoctadecanoyl-CoA + NADP+)
R08945 (11beta,17beta-Dihydroxy-4-androsten-3-one + NAD+ <=> 11beta-Hydroxyandrost-4-ene-3,17-dione + NADH + H+)
R08980 (11beta,17beta-Dihydroxy-4-androsten-3-one + NADP+ <=> 11beta-Hydroxyandrost-4-ene-3,17-dione + NADPH + H+)
R10826 (Very-long-chain (3R)-3-hydroxyacyl-CoA + NADP+ <=> Very-long-chain 3-oxoacyl-CoA + NADPH + H+)
Best hit
| Source | Best Hit ID | Description | E-value |
|---|---|---|---|
| TAIR | AT1G67730.1 | beta-ketoacyl reductase 1. Encodes one of the two Arabidopsis homologues to YBR159w encoding a S. cerevisiae beta-ketoacyl reductase (KCR), which catalyzes the first reduction during VLCFA (very long chain fatty acids, >18 carbon) elongation: KCR1 (At1g67730), KCR2 (At1g24470). Complementation of the yeast ybr159Delta mutant demonstrated that the two KCR proteins are divergent and that only AtKCR1 can restore heterologous elongase activity similar to the native yeast KCR gene. | 0 |
| RefSeq | XP_009768596.1 | PREDICTED: very-long-chain 3-oxoacyl-CoA reductase 1 [Nicotiana sylvestris] | 0 |
| Q8L9C4 | Very-long-chain 3-oxoacyl-CoA reductase 1 OS=Arabidopsis thaliana OX=3702 GN=KCR1 PE=1 SV=1 | 0 | |
| TrEMBL | A0A1J6J4V0 | Very-long-chain 3-oxoacyl-coa reductase 1 OS=Nicotiana attenuata OX=49451 GN=KCR1_1 PE=3 SV=1 | 0 |
Expression
| BioProject | Accession | TPM | Cultivar | Tissue | Development Stage | Sample Name | Description |
|---|---|---|---|---|---|---|---|
| No sample metadata found. | |||||||
Orthology