Basic Information
Locus ID:
gene-LOC132618433
Species & Taxonomic ID:
Lycium barbarum & 112863
Genome Assembly:
GCF_019175385.1
Description:
C2 domain of PTEN tumour-suppressor protein
Maps and Mapping Data
| Chromosome | Start | End | Strand | ID |
|---|---|---|---|---|
| chr11 | 80864572 | 80871540 | - | gene-LOC132618433 |
Protein Data
Protein Properties:
| Theoretical pI | Molecular Weight | Instability Index | Aliphatic Index | GRAVY |
|---|---|---|---|---|
| 8.55 | 48,074.59 Da | 46.05 | 77.31 | -0.41 |
Protein Domain:
| Category | ID | Description | Start | End | Evalue/Score | InterPro ID |
|---|---|---|---|---|---|---|
| CDD | cd14509 | PTP_PTEN | 54 | 207 | 1.24879E-93 | IPR045101 |
| Pfam | PF00782 | Dual specificity phosphatase, catalytic domain | 122 | 190 | 9.8E-6 | IPR000340 |
| Pfam | PF10409 | C2 domain of PTEN tumour-suppressor protein | 320 | 396 | 9.0E-10 | IPR014020 |
| SUPERFAMILY | SSF52799 | (Phosphotyrosine protein) phosphatases II | 51 | 210 | 5.03E-43 | IPR029021 |
| SUPERFAMILY | SSF49562 | C2 domain (Calcium/lipid-binding domain, CaLB) | 298 | 398 | 4.58E-15 | IPR035892 |
| Gene3D | G3DSA:2.60.40.1110 | - | 277 | 400 | 2.3E-10 | - |
| Gene3D | G3DSA:3.90.190.10 | Protein tyrosine phosphatase superfamily | 31 | 212 | 9.8E-71 | IPR029021 |
| SMART | SM01326 | PTEN_C2_2 | 226 | 398 | 1.3E-7 | IPR014020 |
| ProSiteProfiles | PS51182 | C2 tensin-type domain profile. | 244 | 399 | 12.792562 | IPR014020 |
| ProSiteProfiles | PS51181 | Phosphatase tensin-type domain profile. | 44 | 213 | 28.743832 | IPR029023 |
| ProSiteProfiles | PS50056 | Tyrosine specific protein phosphatases domain profile. | 132 | 187 | 12.19706 | IPR000387 |
| ProSitePatterns | PS00383 | Tyrosine specific protein phosphatases active site. | 152 | 162 | - | IPR016130 |
Gene Ontology
Biological Process:
KEGG Pathway
Pathway:
ko00562 (Inositol phosphate metabolism)
map00562 (Inositol phosphate metabolism)
ko01521 (EGFR tyrosine kinase inhibitor resistance)
map01521 (EGFR tyrosine kinase inhibitor resistance)
ko04068 (FoxO signaling pathway)
map04068 (FoxO signaling pathway)
ko04070 (Phosphatidylinositol signaling system)
map04070 (Phosphatidylinositol signaling system)
ko04071 (Sphingolipid signaling pathway)
map04071 (Sphingolipid signaling pathway)
map04115 (p53 signaling pathway)
ko04140 (Autophagy - animal)
map04140 (Autophagy - animal)
ko04150 (mTOR signaling pathway)
map04150 (mTOR signaling pathway)
ko04151 (PI3K-Akt signaling pathway)
map04151 (PI3K-Akt signaling pathway)
ko04212 (Longevity regulating pathway - worm)
map04212 (Longevity regulating pathway - worm)
ko04218 (Cellular senescence)
map04218 (Cellular senescence)
Best hit
| Source | Best Hit ID | Description | E-value |
|---|---|---|---|
| TAIR | AT5G39400.1 | Calcium/lipid-binding (CaLB) phosphatase. | 0 |
| RefSeq | XP_019262897.1 | PREDICTED: phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and protein-tyrosine-phosphatase PTEN1 isoform X1 [Nicotiana attenuata] | 0 |
| Q9FLZ5 | Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and protein-tyrosine-phosphatase PTEN1 OS=Arabidopsis thaliana OX=3702 GN=PTEN1 PE=1 SV=1 | 0 | |
| TrEMBL | A0A1U7XBT9 | phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform X1 OS=Nicotiana sylvestris OX=4096 GN=LOC104232826 PE=3 SV=1 | 0 |
Expression
| BioProject | Accession | TPM | Cultivar | Tissue | Development Stage | Sample Name | Description |
|---|---|---|---|---|---|---|---|
| No sample metadata found. | |||||||
Orthology
| Family | Species | Count | Orthologous Genes |
|---|---|---|---|
| Acanthaceae | Avicennia marina | 1 | jg40221 |
| Anacardiaceae | Pistacia vera | 1 | pistato.v30194150 |
| Arecaceae | Cocos nucifera | 1 | COCNU_05G002110 |
| Arecaceae | Phoenix dactylifera | 1 | gene-LOC103711183 |
| Asparagaceae | Asparagus officinalis | 1 | AsparagusV1_08.1399.V1.1 |
| Asteraceae | Flaveria trinervia | 2 | Ftri13G30120, Ftri18G13125 |
| Brassicaceae | Arabidopsis thaliana | 1 | AT5G39400.1 |
| Brassicaceae | Eutrema salsugineum | 1 | Thhalv10027783m.g.v1.0 |
| Brassicaceae | Schrenkiella parvula | 1 | Sp7g02580.v2.2 |
| Brassicaceae | Brassica nigra | 2 | BniB01g028260.2N, BniB06g060170.2N |
| Casuarinaceae | Casuarina equisetifolia | 1 | Ceq08G0362 |
| Casuarinaceae | Casuarina glauca | 1 | Cgl08G0321 |
| Cymodoceaceae | Cymodocea nodosa | 1 | gene.Cymno14g10710 |
| Nitrariaceae | Nitraria sibirica | 1 | evm.TU.LG02.250 |
| Plantaginaceae | Plantago ovata | 1 | Pov_00028024 |
| Plumbaginaceae | Limonium bicolor | 1 | Lb2G13062 |
| Posidoniaceae | Posidonia oceanica | 1 | gene.Posoc06g20080 |
| Rhizophoraceae | Bruguiera sexangula | 1 | evm.TU.Scaffold_6_RagTag.324 |
| Rhizophoraceae | Carallia pectinifolia | 1 | nbisL1-mrna-15182 |
| Rhizophoraceae | Ceriops tagal | 1 | nbisL1-mrna-14779 |
| Rhizophoraceae | Ceriops zippeliana | 1 | nbisL1-mrna-274 |
| Rhizophoraceae | Kandelia candel | 1 | evm.TU.utg000011l.183 |
| Rhizophoraceae | Kandelia obovata | 1 | Maker00007868 |
| Rhizophoraceae | Rhizophora apiculata | 1 | nbisL1-mrna-11775 |
| Rhizophoraceae | Rhizophora mangle | 1 | nbisL1-mrna-17297 |
| Salicaceae | Populus euphratica | 2 | populus_peu00638, populus_peu24575 |
| Solanaceae | Lycium barbarum | 1 | gene-LOC132618433 |
| Solanaceae | Solanum pennellii | 1 | gene-LOC107013932 |
| Tamaricaceae | Reaumuria soongarica | 1 | gene_7277 |
| Tamaricaceae | Tamarix chinensis | 1 | TC01G1207 |
| Zosteraceae | Zostera marina | 1 | Zosma06g28190.v3.1 |