Basic Information
Locus ID:
gene-LOC114077216
Species & Taxonomic ID:
Solanum pennellii & 28526
Genome Assembly:
GCF_001406875.1
Description:
ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail- anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the membrane-bound receptor, and returning it to the cytosol to initiate a new round of targeting
Maps and Mapping Data
| Chromosome | Start | End | Strand | ID |
|---|---|---|---|---|
| chr5 | 72494491 | 72495903 | + | gene-LOC114077216 |
Protein Data
Protein Properties:
| Theoretical pI | Molecular Weight | Instability Index | Aliphatic Index | GRAVY |
|---|---|---|---|---|
| 8.84 | 46,416.88 Da | 48.30 | 84.52 | -0.36 |
Protein Domain:
| Category | ID | Description | Start | End | Evalue/Score | InterPro ID |
|---|---|---|---|---|---|---|
| Pfam | PF00069 | Protein kinase domain | 263 | 382 | 3.6E-8 | IPR000719 |
| SUPERFAMILY | SSF56112 | Protein kinase-like (PK-like) | 31 | 395 | 6.0E-22 | IPR011009 |
| Gene3D | G3DSA:1.10.510.10 | Transferase(Phosphotransferase) domain 1 | 83 | 391 | 4.2E-19 | - |
| SMART | SM00220 | serkin_6 | 32 | 382 | 2.3E-7 | IPR000719 |
| ProSiteProfiles | PS50011 | Protein kinase domain profile. | 32 | 382 | 16.796152 | IPR000719 |
Gene Ontology
Biological Process:
Molecular Function:
KEGG Pathway
Best hit
| Source | Best Hit ID | Description | E-value |
|---|---|---|---|
| RefSeq | XP_027772728.1 | serine/threonine-protein kinase BLUS1-like [Solanum pennellii] | 0 |
| TrEMBL | K4C180 | Protein kinase domain-containing protein OS=Solanum lycopersicum OX=4081 PE=4 SV=1 | 0 |
Expression
| BioProject | Accession | TPM | Cultivar | Tissue | Development Stage | Sample Name | Description |
|---|---|---|---|---|---|---|---|
| No sample metadata found. | |||||||
Orthology
| Family | Species | Count | Orthologous Genes |
|---|---|---|---|
| Acanthaceae | Avicennia marina | 3 | jg18682, jg1869, jg8331 |
| Anacardiaceae | Pistacia vera | 1 | pistato.v30003640 |
| Apiaceae | Apium graveolens | 2 | Ag2G02557, AgUnG00499 |
| Solanaceae | Lycium barbarum | 5 | gene-LOC132613084, gene-LOC132613089, gene-LOC132613094 ... |
| Solanaceae | Solanum chilense | 5 | SOLCI000552200, SOLCI001268300, SOLCI001371800 ... |
| Solanaceae | Solanum pennellii | 7 | gene-LOC107019742, gene-LOC107032678, gene-LOC107032679 ... |