HalophFGD

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Basic Information
Locus ID: gene-BS78_05G039500
Species & Taxonomic ID: Paspalum vaginatum & 158149
Genome Assembly: GCA_026573395.1
Description: 2-isopropylmalate synthase
Maps and Mapping Data
Chromosome Start End Strand ID
chr5 3592293 3599027 + gene-BS78_05G039500
Protein Data
Protein Properties:
Theoretical pI Molecular Weight Instability Index Aliphatic Index GRAVY
6.34 67,326.51 Da 43.13 89.13 -0.15
Protein Domain:
Category ID Description Start End Evalue/Score InterPro ID
CDD cd07940 DRE_TIM_IPMS 87 366 8.62393E-173 -
Pfam PF08502 LeuA allosteric (dimerisation) domain 464 607 6.2E-34 IPR013709
Pfam PF00682 HMGL-like 85 364 2.3E-91 IPR000891
SUPERFAMILY SSF110921 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain 492 607 1.44E-15 IPR036230
SUPERFAMILY SSF51569 Aldolase 82 382 4.94E-89 -
Gene3D G3DSA:3.20.20.70 Aldolase class I 80 368 2.1E-96 IPR013785
Gene3D G3DSA:3.30.160.270 - 487 608 1.6E-22 IPR036230
Gene3D G3DSA:1.10.238.260 - 371 483 4.3E-36 -
SMART SM00917 LeuA_dimer_2 463 608 9.1E-27 IPR013709
TIGRFAM TIGR00973 leuA_bact: 2-isopropylmalate synthase 85 605 7.3E-199 IPR005671
ProSiteProfiles PS50991 Pyruvate carboxyltransferase domain. 85 358 41.433441 IPR000891
ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 92 108 - IPR002034
Hamap MF_01025 2-isopropylmalate synthase [leuA]. 82 617 39.313328 IPR005671
MobiDBLite mobidb-lite consensus disorder prediction 1 34 - -
MobiDBLite mobidb-lite consensus disorder prediction 1 18 - -
Gene Ontology
Biological Process:
GO:0009098 (L-leucine biosynthetic process) GO:0019752 (carboxylic acid metabolic process)
Molecular Function:
GO:0003824 (catalytic activity) GO:0003852 (2-isopropylmalate synthase activity) GO:0046912 (acyltransferase activity, acyl groups converted into alkyl on transfer)
KEGG Pathway
KO Term:
K01649 (2-isopropylmalate synthase [EC:2.3.3.13])
Pathway:
ko00290 (Valine, leucine and isoleucine biosynthesis) map00290 (Valine, leucine and isoleucine biosynthesis) ko00620 (Pyruvate metabolism) map00620 (Pyruvate metabolism) ko01100 (Metabolic pathways) map01100 (Metabolic pathways) ko01110 (Biosynthesis of secondary metabolites) map01110 (Biosynthesis of secondary metabolites) ko01210 (2-Oxocarboxylic acid metabolism) map01210 (2-Oxocarboxylic acid metabolism) ko01230 (Biosynthesis of amino acids) map01230 (Biosynthesis of amino acids)
Module:
M00432 (Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate)
Reaction:
R01213 (alpha-Isopropylmalate + CoA <=> Acetyl-CoA + 3-Methyl-2-oxobutanoic acid + H2O)
Best hit
Source Best Hit ID Description E-value
TAIR AT1G74040.1 2-isopropylmalate synthase 1. Encodes an active Arabidopsis isopropylmalate synthase IPMS2. Involved in leucine biosynthesis. Do not participate in the chain elongation of glucosinolates. Expressed constitutively throughout the plant. Loss of IPMS2 can be compensated by a second isopropylmalate synthase gene IPMS1 (At1g18500). 0
RefSeq XP_025808491.1 2-isopropylmalate synthase A-like [Panicum hallii] 0
Swiss-Prot O04973 2-isopropylmalate synthase A OS=Solanum pennellii OX=28526 GN=IPMSA PE=2 SV=1 0
TrEMBL A0A2S3H5Q7 2-isopropylmalate synthase OS=Panicum hallii OX=206008 GN=PAHAL_3G022400 PE=3 SV=1 0
Expression
First Prev Next Last
BioProject Accession TPM Cultivar Tissue Development Stage Sample Name Description
No sample metadata found.
Network
🔍 Protein-Protein Interaction Network
Orthology
Family Species Count Orthologous Genes
Acanthaceae Avicennia marina 3 jg10976, jg10977, jg5907
Aizoaceae Mesembryanthemum crystallinum 2 gene_15767, gene_19447
Amaranthaceae Atriplex hortensis 2 Ah019627, Ah019628
Amaranthaceae Beta vulgaris 2 BVRB_3g058810, BVRB_3g058820
Amaranthaceae Salicornia bigelovii 2 Sbi_jg38490, Sbi_jg6594
Amaranthaceae Salicornia europaea 1 Seu_jg15332
Amaranthaceae Suaeda aralocaspica 2 GOSA_00006427, GOSA_00006428
Amaranthaceae Suaeda glauca 6 Sgl01897, Sgl01898, Sgl07038, Sgl07039, Sgl44504, Sgl49273
Amaranthaceae Chenopodium album 3 gene:ENSEOMG00000011743, gene:ENSEOMG00000030441 ...
gene:ENSEOMG00000042931
Amaranthaceae Chenopodium quinoa 2 CQ.Regalona.r1.3AG0011030, CQ.Regalona.r1.3BG0011260
Anacardiaceae Pistacia vera 1 pistato.v30243490
Apiaceae Apium graveolens 1 Ag5G02859
Arecaceae Cocos nucifera 1 COCNU_12G004560
Arecaceae Phoenix dactylifera 1 gene-LOC103705082
Asparagaceae Asparagus officinalis 4 AsparagusV1_04.1953.V1.1, AsparagusV1_04.1955.V1.1 ...
AsparagusV1_Unassigned.957.V1.1, AsparagusV1_Unassigned.958.V1.1
Asteraceae Flaveria trinervia 2 Ftri11G03059, Ftri12G07723
Brassicaceae Arabidopsis thaliana 4 AT1G18500.1, AT1G74040.1, AT5G23010.1, AT5G23020.1
Brassicaceae Eutrema salsugineum 5 Thhalv10003976m.g.v1.0, Thhalv10004072m.g.v1.0 ...
Thhalv10005522m.g.v1.0, Thhalv10007073m.g.v1.0, Thhalv10018267m.g.v1.0
Brassicaceae Schrenkiella parvula 5 Sp1g16450.v2.2, Sp2g24100.v2.2, Sp2g24110.v2.2 ...
Sp5g29260.v2.2, Sp6g02930.v2.2
Brassicaceae Brassica nigra 8 BniB02g076300.2N, BniB02g076310.2N, BniB03g028050.2N ...
BniB04g003060.2N, BniB04g032970.2N, BniB05g055400.2N, BniB08g036280.2N, BniB08g045890.2N
Casuarinaceae Casuarina equisetifolia 2 Ceq06G2205, Ceq09G0942
Casuarinaceae Casuarina glauca 2 Cgl06G2325, Cgl09G1024
Cymodoceaceae Cymodocea nodosa 1 gene.Cymno05g02310
Dunaliellaceae Dunaliella salina 2 Dusal.0217s00013.v1.0, Dusal.0217s00014.v1.0
Hydrocharitaceae Thalassia testudinum 1 gene.Thate08g08470
Nitrariaceae Nitraria sibirica 4 evm.TU.LG02.2457, evm.TU.LG11.123, evm.TU.LG11.124 ...
evm.TU.LG11.125
Plantaginaceae Plantago ovata 2 Pov_00023467, Pov_00026884
Plumbaginaceae Limonium bicolor 1 Lb7G33591
Poaceae Echinochloa crus-galli 10 AH02.813, AH04.240, AH05.159, BH02.108, BH02.135, BH04.237 ...
BH05.184, CH02.161, CH04.256, CH05.242
Poaceae Eleusine coracana subsp. coracana 4 gene-QOZ80_5AG0380830, gene-QOZ80_5BG0427930 ...
gene-QOZ80_9AG0674100, gene-QOZ80_9BG0697880
Poaceae Hordeum vulgare 1 HORVU.MOREX.r3.5HG0460900.1
Poaceae Lolium multiflorum 3 gene-QYE76_003279, gene-QYE76_003349, gene-QYE76_052410
Poaceae Oryza coarctata 4 Oco21G000770, Oco22G001620, Oco23G001530, Oco24G000960
Poaceae Oryza sativa 2 LOC_Os11g04670.1, LOC_Os12g04440.1
Poaceae Paspalum vaginatum 1 gene-BS78_05G039500
Poaceae Puccinellia tenuiflora 3 Pt_Chr0500049, Pt_Chr0703001, Pt_Chr0703081
Poaceae Sporobolus alterniflorus 2 Chr16G009170, Chr17G008190
Poaceae Thinopyrum elongatum 1 Tel5E01G238500
Poaceae Triticum dicoccoides 3 gene_TRIDC5AG022230, gene_TRIDC5BG023720 ...
gene_TRIDC7AG022330
Poaceae Triticum aestivum 4 TraesCS5A02G131300.1, TraesCS5B02G133500.1 ...
TraesCS5D02G139800.1, TraesCS7A02G179500.1
Poaceae Zea mays 4 Zm00001eb093160_P001, Zm00001eb196510_P001 ...
Zm00001eb278820_P001, Zm00001eb405040_P001
Poaceae Zoysia japonica 2 nbis-gene-27033, nbis-gene-51079
Poaceae Zoysia macrostachya 1 Zma_g18398
Portulacaceae Portulaca oleracea 4 evm.TU.LG04.828, evm.TU.LG05.2106, evm.TU.LG06.1512 ...
evm.TU.LG11.875
Posidoniaceae Posidonia oceanica 1 gene.Posoc01g05010
Rhizophoraceae Bruguiera sexangula 1 evm.TU.Scaffold_3_RagTag.1457
Rhizophoraceae Carallia pectinifolia 1 nbisL1-mrna-1766
Rhizophoraceae Ceriops tagal 1 nbisL1-mrna-1548
Rhizophoraceae Ceriops zippeliana 1 nbisL1-mrna-2684
Rhizophoraceae Kandelia candel 1 evm.TU.utg000019l.366
Rhizophoraceae Kandelia obovata 1 Maker00001810
Rhizophoraceae Rhizophora apiculata 1 nbisL1-mrna-12297
Rhizophoraceae Rhizophora mangle 1 nbisL1-mrna-12819
Salicaceae Populus euphratica 1 populus_peu13845
Solanaceae Lycium barbarum 2 gene-LOC132609321, gene-LOC132643462
Solanaceae Solanum chilense 3 SOLCI004281200, SOLCI006467400, SOLCI006806900
Solanaceae Solanum pennellii 5 gene-LOC107023302, gene-LOC107026725, gene-LOC107026726 ...
gene-LOC107028537, gene-LOC107032143
Tamaricaceae Reaumuria soongarica 1 STRG.14313_chr08_-
Tamaricaceae Tamarix chinensis 1 TC12G1851
Zosteraceae Zostera marina 2 Zosma02g23460.v3.1, Zosma03g21940.v3.1
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