halophFGD

Basic Information

Locus ID: evm.TU.utg000009l.570

Species & Taxonomic ID: Kandelia candel & 61147

Genome Assembly: GCA_037832225.1

Description: E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin- conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates

Maps and Mapping Data

Chromosome	Start	End	Strand	ID
PERG.utg000009l	6432188	6438584	-	evm.TU.utg000009l.570

Protein Data

Protein Properties:

Theoretical pI	Molecular Weight	Instability Index	Aliphatic Index	GRAVY
8.21	75,085.88 Da	35.57	78.65	-0.32

Protein Domain:

Category	ID	Description	Start	End	Evalue/Score	InterPro ID
CDD	cd16571	RING-HC_SIAHs	57	95	4.74495E-16	-
CDD	cd03829	Sina	173	301	5.97926E-60	-
Pfam	PF07714	Protein tyrosine and serine/threonine kinase	394	667	6.1E-45	IPR001245
Pfam	PF03145	Seven in absentia protein family	101	300	1.0E-80	IPR018121
SUPERFAMILY	SSF57850	RING/U-box	53	99	5.89E-5	-
SUPERFAMILY	SSF56112	Protein kinase-like (PK-like)	368	667	1.78E-68	IPR011009
SUPERFAMILY	SSF49599	TRAF domain-like	112	304	7.85E-47	-
Gene3D	G3DSA:1.10.510.10	Transferase(Phosphotransferase) domain 1	467	677	5.7E-58	-
Gene3D	G3DSA:2.60.210.10	Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2; Chain A	168	300	5.9E-38	IPR008974
Gene3D	G3DSA:3.30.40.10	Zinc/RING finger domain, C3HC4 (zinc finger)	112	167	2.0E-17	IPR013083
Gene3D	G3DSA:3.30.200.20	Phosphorylase Kinase; domain 1	355	465	1.8E-22	-
Gene3D	G3DSA:3.30.40.10	Zinc/RING finger domain, C3HC4 (zinc finger)	27	111	9.1E-7	IPR013083
SMART	SM00219	tyrkin_6	389	667	3.6E-25	IPR020635
ProSiteProfiles	PS50011	Protein kinase domain profile.	389	671	35.212753	IPR000719
ProSiteProfiles	PS50089	Zinc finger RING-type profile.	59	95	9.228865	IPR001841
ProSiteProfiles	PS51081	Zinc finger SIAH-type profile.	112	172	14.11725	IPR013010
ProSitePatterns	PS00109	Tyrosine protein kinases specific active-site signature.	517	529	-	IPR008266
ProSitePatterns	PS00107	Protein kinases ATP-binding region signature.	395	418	-	IPR017441

Gene Ontology

Biological Process:

GO:0006468 (protein phosphorylation) GO:0006511 (ubiquitin-dependent protein catabolic process) GO:0007275 (multicellular organism development)

Molecular Function:

GO:0004672 (protein kinase activity) GO:0004713 (protein tyrosine kinase activity) GO:0005515 (protein binding) GO:0005524 (ATP binding) GO:0008270 (zinc ion binding)

Cellular Component:

GO:0005737 (cytoplasm)

KEGG Pathway

KO Term:

K04506 (E3 ubiquitin-protein ligase SIAH1 [EC:2.3.2.27])

Pathway:

ko04013 (MAPK signaling pathway - fly) map04013 (MAPK signaling pathway - fly) map04115 (p53 signaling pathway) ko04120 (Ubiquitin mediated proteolysis) map04120 (Ubiquitin mediated proteolysis) ko04310 (Wnt signaling pathway) map04310 (Wnt signaling pathway)

Best hit

Source	Best Hit ID	Description
TAIR	AT2G41970.1	Protein kinase superfamily protein.
RefSeq	XP_024458201.1	probable protein kinase At2g41970 [Populus trichocarpa]
Swiss-Prot	P93749	Probable protein kinase At2g41970 OS=Arabidopsis thaliana OX=3702 GN=At2g41970 PE=2 SV=1
TrEMBL	A0A1R3KYD5	RING-type E3 ubiquitin transferase OS=Corchorus capsularis OX=210143 GN=CCACVL1_00131 PE=3 SV=1

Expression

BioProject	Accession	TPM	Cultivar	Tissue	Development Stage	Sample Name	Description
No sample metadata found.

Network

No network data available for this species.

Orthology

Family	Species	Count	Orthologous Genes
Rhizophoraceae	Kandelia candel	1	evm.TU.utg000009l.570
Rhizophoraceae	Rhizophora apiculata	1	nbisL1-mrna-12475