Basic Information
Locus ID:
Thhalv10024249m.g.v1.0
Species & Taxonomic ID:
Eutrema salsugineum & 72664
Genome Assembly:
GCF_000478725.1
Short Name:
BRI1
Description:
Belongs to the protein kinase superfamily. Ser Thr protein kinase family
Maps and Mapping Data
| Chromosome | Start | End | Strand | ID |
|---|---|---|---|---|
| scaffold_1 | 469307 | 473302 | + | Thhalv10024249m.g.v1.0 |
Protein Data
Protein Properties:
| Theoretical pI | Molecular Weight | Instability Index | Aliphatic Index | GRAVY |
|---|---|---|---|---|
| 6.47 | 130,410.93 Da | 32.85 | 93.03 | -0.07 |
Protein Domain:
| Category | ID | Description | Start | End | Evalue/Score | InterPro ID |
|---|---|---|---|---|---|---|
| CDD | cd14066 | STKc_IRAK | 889 | 1158 | 1.66759E-100 | - |
| Pfam | PF08263 | Leucine rich repeat N-terminal domain | 36 | 69 | 1.1E-6 | IPR013210 |
| Pfam | PF00560 | Leucine Rich Repeat | 418 | 439 | 0.43 | IPR001611 |
| Pfam | PF00560 | Leucine Rich Repeat | 247 | 268 | 0.35 | IPR001611 |
| Pfam | PF00560 | Leucine Rich Repeat | 367 | 388 | 1.4 | IPR001611 |
| Pfam | PF13855 | Leucine rich repeat | 489 | 547 | 1.0E-7 | IPR001611 |
| Pfam | PF13855 | Leucine rich repeat | 682 | 738 | 1.0E-6 | IPR001611 |
| Pfam | PF00069 | Protein kinase domain | 883 | 1152 | 1.5E-44 | IPR000719 |
| SUPERFAMILY | SSF52058 | L domain-like | 171 | 408 | 3.13E-47 | - |
| SUPERFAMILY | SSF52058 | L domain-like | 93 | 213 | 3.06E-11 | - |
| SUPERFAMILY | SSF56112 | Protein kinase-like (PK-like) | 869 | 1159 | 8.77E-75 | IPR011009 |
| SUPERFAMILY | SSF52058 | L domain-like | 414 | 769 | 1.12E-56 | - |
| Gene3D | G3DSA:3.30.200.20 | Phosphorylase Kinase; domain 1 | 843 | 958 | 2.4E-37 | - |
| Gene3D | G3DSA:1.10.510.10 | Transferase(Phosphotransferase) domain 1 | 959 | 1160 | 1.6E-62 | - |
| Gene3D | G3DSA:3.30.1490.310 | - | 590 | 651 | 0.0 | - |
| Gene3D | G3DSA:3.80.10.10 | Ribonuclease Inhibitor | 39 | 770 | 0.0 | IPR032675 |
| SMART | SM00369 | LRR_typ_2 | 535 | 559 | 38.0 | IPR003591 |
| SMART | SM00369 | LRR_typ_2 | 364 | 388 | 77.0 | IPR003591 |
| SMART | SM00369 | LRR_typ_2 | 290 | 314 | 91.0 | IPR003591 |
| SMART | SM00220 | serkin_6 | 883 | 1155 | 1.7E-35 | IPR000719 |
| SMART | SM00369 | LRR_typ_2 | 701 | 725 | 46.0 | IPR003591 |
| SMART | SM00369 | LRR_typ_2 | 172 | 202 | 20.0 | IPR003591 |
| SMART | SM00369 | LRR_typ_2 | 487 | 511 | 44.0 | IPR003591 |
| ProSiteProfiles | PS50011 | Protein kinase domain profile. | 883 | 1158 | 37.262184 | IPR000719 |
| ProSitePatterns | PS00107 | Protein kinases ATP-binding region signature. | 889 | 912 | - | IPR017441 |
| ProSitePatterns | PS00108 | Serine/Threonine protein kinases active-site signature. | 1005 | 1017 | - | IPR008271 |
| PRINTS | PR00019 | Leucine-rich repeat signature | 172 | 185 | 1.0E-5 | - |
| PRINTS | PR00019 | Leucine-rich repeat signature | 124 | 137 | 1.0E-5 | - |
Gene Ontology
Biological Process:
Molecular Function:
KEGG Pathway
Best hit
| Source | Best Hit ID | Description | E-value |
|---|---|---|---|
| TAIR | AT4G39400.1 | Leucine-rich receptor-like protein kinase family protein. Encodes a plasma membrane localized leucine-rich repeat receptor kinase involved in brassinosteroid signal transduction. BRI1 ligand is brassinolide which binds at the extracellular domain. Binding results in phosphorylation of the kinase domain which activates the BRI1 protein leading to BR responses. Residue T-1049 and either S-1044 or T-1045 were essential for kinase function in vitro and normal BRI1 signaling in planta. Although BAK1 and BRI1 alone localize in the plasma membrane, when BAK1 and BRI1 are coexpressed, the heterodimer BAK1/BRI1 they form is localized in the endosome. BRI1 appears to be involved in the autonomous pathway that regulates the transition to flowering, primarily through its effects on FLC expression levels, as uncovered by double mutant analyses. This most likely occurs as a result of BRI1-dependent effects on histone acetylation, but not histone triMeH3K4 methylation, at the FLC locus. | 0 |
| RefSeq | XP_006411743.1 | protein BRASSINOSTEROID INSENSITIVE 1 [Eutrema salsugineum] | 0 |
| O22476 | Protein BRASSINOSTEROID INSENSITIVE 1 OS=Arabidopsis thaliana OX=3702 GN=BRI1 PE=1 SV=1 | 0 | |
| TrEMBL | V4P1K0 | non-specific serine/threonine protein kinase OS=Eutrema salsugineum OX=72664 GN=EUTSA_v10024249mg PE=3 SV=1 | 0 |
Expression
| BioProject | Accession | TPM | Cultivar | Tissue | Development Stage | Sample Name | Description |
|---|---|---|---|---|---|---|---|
| No sample metadata found. | |||||||
Orthology