Basic Information
Locus ID:
Thhalv10008291m.g.v1.0
Species & Taxonomic ID:
Eutrema salsugineum & 72664
Genome Assembly:
GCF_000478725.1
Description:
Very-long-chain 3-oxoacyl-CoA reductase-like protein At1g24470
Maps and Mapping Data
| Chromosome | Start | End | Strand | ID |
|---|---|---|---|---|
| scaffold_5 | 5954849 | 5957403 | + | Thhalv10008291m.g.v1.0 |
Protein Data
Protein Properties:
| Theoretical pI | Molecular Weight | Instability Index | Aliphatic Index | GRAVY |
|---|---|---|---|---|
| 9.96 | 34,241.64 Da | 35.47 | 105.15 | 0.20 |
Protein Domain:
| Category | ID | Description | Start | End | Evalue/Score | InterPro ID |
|---|---|---|---|---|---|---|
| CDD | cd05356 | 17beta-HSD1_like_SDR_c | 45 | 287 | 1.54389E-101 | - |
| Pfam | PF00106 | short chain dehydrogenase | 47 | 239 | 3.2E-37 | IPR002347 |
| SUPERFAMILY | SSF51735 | NAD(P)-binding Rossmann-fold domains | 43 | 293 | 8.54E-49 | IPR036291 |
| Gene3D | G3DSA:3.40.50.720 | - | 41 | 271 | 2.5E-48 | - |
| PIRSF | PIRSF000126 | 11-beta-HSD1 | 1 | 305 | 4.1E-94 | - |
| PRINTS | PR00080 | Short-chain dehydrogenase/reductase (SDR) superfamily signature | 121 | 132 | 3.7E-6 | IPR002347 |
| PRINTS | PR00080 | Short-chain dehydrogenase/reductase (SDR) superfamily signature | 176 | 184 | 3.7E-6 | IPR002347 |
| PRINTS | PR00081 | Glucose/ribitol dehydrogenase family signature | 170 | 186 | 6.9E-18 | IPR002347 |
| PRINTS | PR00080 | Short-chain dehydrogenase/reductase (SDR) superfamily signature | 198 | 217 | 3.7E-6 | IPR002347 |
| PRINTS | PR00081 | Glucose/ribitol dehydrogenase family signature | 219 | 236 | 6.9E-18 | IPR002347 |
| PRINTS | PR00081 | Glucose/ribitol dehydrogenase family signature | 121 | 132 | 6.9E-18 | IPR002347 |
| PRINTS | PR00081 | Glucose/ribitol dehydrogenase family signature | 198 | 217 | 6.9E-18 | IPR002347 |
| PRINTS | PR00081 | Glucose/ribitol dehydrogenase family signature | 47 | 64 | 6.9E-18 | IPR002347 |
Gene Ontology
Molecular Function:
KEGG Pathway
Pathway:
ko00062 (Fatty acid elongation)
map00062 (Fatty acid elongation)
ko00140 (Steroid hormone biosynthesis)
map00140 (Steroid hormone biosynthesis)
ko01040 (Biosynthesis of unsaturated fatty acids)
map01040 (Biosynthesis of unsaturated fatty acids)
ko01100 (Metabolic pathways)
map01100 (Metabolic pathways)
ko01110 (Biosynthesis of secondary metabolites)
map01110 (Biosynthesis of secondary metabolites)
ko01212 (Fatty acid metabolism)
map01212 (Fatty acid metabolism)
Reaction:
R02352 (Estradiol-17beta + NAD+ <=> Estrone + NADH + H+)
R02353 (Estradiol-17beta + NADP+ <=> Estrone + NADPH + H+)
R04681 (Estriol + NAD+ <=> 16alpha-Hydroxyestrone + NADH + H+)
R04682 (Estriol + NADP+ <=> 16alpha-Hydroxyestrone + NADPH + H+)
R07759 (3-Oxostearoyl-CoA + NADPH + H+ <=> 3-Hydroxyoctadecanoyl-CoA + NADP+)
R08945 (11beta,17beta-Dihydroxy-4-androsten-3-one + NAD+ <=> 11beta-Hydroxyandrost-4-ene-3,17-dione + NADH + H+)
R08980 (11beta,17beta-Dihydroxy-4-androsten-3-one + NADP+ <=> 11beta-Hydroxyandrost-4-ene-3,17-dione + NADPH + H+)
R10826 (Very-long-chain (3R)-3-hydroxyacyl-CoA + NADP+ <=> Very-long-chain 3-oxoacyl-CoA + NADPH + H+)
Best hit
| Source | Best Hit ID | Description | E-value |
|---|---|---|---|
| TAIR | AT1G24470.1 | beta-ketoacyl reductase 2. Encodes one of the two Arabidopsis homologues to YBR159w encoding a S. cerevisiae beta-ketoacyl reductase (KCR), which catalyzes the first reduction during VLCFA (very long chain fatty acids, >18 carbon) elongation: KCR1 (At1g67730), KCR2 (At1g24470). Complementation of the yeast ybr159Delta mutant demonstrated that the two KCR proteins are divergent and that only AtKCR1 can restore heterologous elongase activity similar to the native yeast KCR gene. | 0 |
| RefSeq | XP_006415805.1 | very-long-chain 3-oxoacyl-CoA reductase-like protein At1g24470 [Eutrema salsugineum] | 0 |
| Q9FYL6 | Very-long-chain 3-oxoacyl-CoA reductase-like protein At1g24470 OS=Arabidopsis thaliana OX=3702 GN=KCR2 PE=2 SV=1 | 0 | |
| TrEMBL | V4L335 | Very-long-chain 3-oxoacyl-CoA reductase-like protein OS=Eutrema salsugineum OX=72664 GN=EUTSA_v10008291mg PE=3 SV=1 | 0 |
Expression
| BioProject | Accession | TPM | Cultivar | Tissue | Development Stage | Sample Name | Description |
|---|---|---|---|---|---|---|---|
| No sample metadata found. | |||||||
Orthology