halophFGD

Basic Information

Locus ID: Sbi_jg46764

Species & Taxonomic ID: Salicornia bigelovii & 46105

Genome Assembly:

Description: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate

Maps and Mapping Data

Chromosome	Start	End	Strand	ID
ptg000003l	13312977	13324875	-	Sbi_jg46764

Protein Data

Protein Properties:

Theoretical pI	Molecular Weight	Instability Index	Aliphatic Index	GRAVY
8.69	28,527.96 Da	43.27	103.66	0.01

Protein Domain:

Category	ID	Description	Start	End	Evalue/Score	InterPro ID
Pfam	PF00180	Isocitrate/isopropylmalate dehydrogenase	92	237	2.4E-45	IPR024084
SUPERFAMILY	SSF53659	Isocitrate/Isopropylmalate dehydrogenase-like	52	237	5.55E-44	-
Gene3D	G3DSA:3.40.718.10	Isopropylmalate Dehydrogenase	41	84	3.0E-5	-
Gene3D	G3DSA:3.40.718.10	Isopropylmalate Dehydrogenase	85	241	1.7E-44	-
SMART	SM01329	Iso_dh_2	53	252	4.0E-15	IPR024084

Gene Ontology

Molecular Function:

GO:0016616 (oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)

KEGG Pathway

KO Term:

K00052 (3-isopropylmalate dehydrogenase [EC:1.1.1.85])

Pathway:

ko00290 (Valine, leucine and isoleucine biosynthesis) map00290 (Valine, leucine and isoleucine biosynthesis) ko00660 (C5-Branched dibasic acid metabolism) map00660 (C5-Branched dibasic acid metabolism) ko01100 (Metabolic pathways) map01100 (Metabolic pathways) ko01110 (Biosynthesis of secondary metabolites) map01110 (Biosynthesis of secondary metabolites) ko01210 (2-Oxocarboxylic acid metabolism) map01210 (2-Oxocarboxylic acid metabolism) ko01230 (Biosynthesis of amino acids) map01230 (Biosynthesis of amino acids)

Module:

M00432 (Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate) M00535 (Isoleucine biosynthesis, pyruvate => 2-oxobutanoate)

Reaction:

R00994 (2-Oxobutanoate + CO2 + NADH + H+ <=> D-erythro-3-Methylmalate + NAD+) R04426 ((2R,3S)-3-Isopropylmalate + NAD+ <=> (2S)-2-Isopropyl-3-oxosuccinate + NADH + H+) R10052 ((2R,3S)-3-Isopropylmalate + NAD+ <=> 4-Methyl-2-oxopentanoate + CO2 + NADH + H+)

Best hit

Source	Best Hit ID	Description
TAIR	AT1G80560.1	isopropylmalate dehydrogenase 2. The AtIMD2 is one out of 3 genes encoding the enzyme 3-isopropylmalate dehydrogenase involved in leucine biosynthesis in Arabidopsis. Its subcellular location has been targeted to plastids.
RefSeq	XP_021731756.1	3-isopropylmalate dehydrogenase 2, chloroplastic-like [Chenopodium quinoa]
Swiss-Prot	P93832	3-isopropylmalate dehydrogenase 2, chloroplastic OS=Arabidopsis thaliana OX=3702 GN=IMDH2 PE=1 SV=1
TrEMBL	A0A803LE56	3-isopropylmalate dehydrogenase OS=Chenopodium quinoa OX=63459 PE=3 SV=1

Expression

BioProject	Accession	TPM	Cultivar	Tissue	Development Stage	Sample Name	Description
No sample metadata found.

Network

🔍 Protein-Protein Interaction Network

Orthology

Family	Species	Count	Orthologous Genes
Acanthaceae	Avicennia marina	2	jg18287, jg528
Aizoaceae	Mesembryanthemum crystallinum	2	gene_25751, gene_26229
Amaranthaceae	Atriplex hortensis	1	Ah010419
Amaranthaceae	Beta vulgaris	1	BVRB_9g219010
Amaranthaceae	Salicornia bigelovii	3	Sbi_jg11636, Sbi_jg46763, Sbi_jg46764
Amaranthaceae	Salicornia europaea	1	Seu_jg20890
Amaranthaceae	Suaeda aralocaspica	1	GOSA_00005123
Amaranthaceae	Suaeda glauca	3	Sgl56347, Sgl61180, Sgl61877
Amaranthaceae	Chenopodium album	3	gene:ENSEOMG00000018016, gene:ENSEOMG00000038486 ... gene:ENSEOMG00000050924
Amaranthaceae	Chenopodium quinoa	2	CQ.Regalona.r1.7BG0009150, CQ.Regalona.r1.9AG0015370
Anacardiaceae	Pistacia vera	2	pistato.v30129510, pistato.v30129560
Apiaceae	Apium graveolens	1	Ag9G01190
Arecaceae	Cocos nucifera	1	COCNU_16G001040
Arecaceae	Phoenix dactylifera	1	gene-LOC103714417
Asparagaceae	Asparagus officinalis	1	AsparagusV1_Unassigned.879.V1.1
Asteraceae	Flaveria trinervia	1	Ftri16G21300
Brassicaceae	Arabidopsis thaliana	4	AT1G31180.1, AT1G80555.1, AT1G80560.1, AT5G14200.1
Brassicaceae	Eutrema salsugineum	2	Thhalv10013695m.g.v1.0, Thhalv10018649m.g.v1.0
Brassicaceae	Schrenkiella parvula	5	Sp5g29930.v2.2, Sp5g35220.v2.2, Sp5g35230.v2.2 ... Sp6g29830.v2.2, SpUn0049_0030.v2.2
Brassicaceae	Brassica nigra	6	BniB05g024330.2N, BniB05g075620.2N, BniB05g075630.2N ... BniB05g075660.2N, BniB05g075670.2N, BniB06g068370.2N
Casuarinaceae	Casuarina equisetifolia	2	Ceq02G0369, Ceq02G0401
Casuarinaceae	Casuarina glauca	1	Cgl02G0390
Cymodoceaceae	Cymodocea nodosa	2	gene.Cymno02g16450, gene.Cymno02g16760
Dunaliellaceae	Dunaliella salina	1	Dusal.0239s00002.v1.0
Hydrocharitaceae	Thalassia testudinum	1	gene.Thate04g18480
Nitrariaceae	Nitraria sibirica	1	evm.TU.LG03.1966
Plantaginaceae	Plantago ovata	1	Pov_00034531
Plumbaginaceae	Limonium bicolor	2	Lb7G32910, Lb7G32911
Poaceae	Echinochloa crus-galli	3	AH09.2783, BH09.3019, CH09.3186
Poaceae	Eleusine coracana subsp. coracana	2	gene-QOZ80_4AG0298620, gene-QOZ80_4BG0329320
Poaceae	Hordeum vulgare	1	HORVU.MOREX.r3.2HG0214780.1
Poaceae	Lolium multiflorum	3	gene-QYE76_011123, gene-QYE76_017999, gene-QYE76_049572
Poaceae	Oryza coarctata	2	Oco05G019360, Oco06G020270
Poaceae	Oryza sativa	1	LOC_Os03g45320.1
Poaceae	Paspalum vaginatum	1	gene-BS78_06G291900
Poaceae	Puccinellia tenuiflora	2	Pt_Chr0206518, Pt_Chr0306994
Poaceae	Sporobolus alterniflorus	4	Chr05G015640, Chr23G000380, Chr25G000320, Chr26G018810
Poaceae	Thinopyrum elongatum	2	Tel2E01G995400, Tel3E01G007700
Poaceae	Triticum dicoccoides	5	gene_TRIDC1BG004300, gene_TRIDC2AG080070 ... gene_TRIDC2BG088160, gene_TRIDC3AG002820, gene_TRIDC3BG000830
Poaceae	Triticum aestivum	6	TraesCS2A02G577600.1, TraesCS2B02G609800.1 ... TraesCS2D02G589000.1, TraesCS3B02G006100.1, TraesCS3D02G007500.1, TraesCSU02G040000.1
Poaceae	Zea mays	3	Zm00001eb013290_P001, Zm00001eb076030_P001 ... Zm00001eb434270_P001
Poaceae	Zoysia japonica	1	nbis-gene-18097
Poaceae	Zoysia macrostachya	2	Zma_g22277, Zma_g27771
Portulacaceae	Portulaca oleracea	2	evm.TU.LG07.1807, evm.TU.LG15.1362
Posidoniaceae	Posidonia oceanica	3	gene.Posoc04g05940, gene.Posoc04g05950, gene.Posoc08g09870
Rhizophoraceae	Bruguiera sexangula	1	evm.TU.Scaffold_18_RagTag.303
Rhizophoraceae	Carallia pectinifolia	1	nbisL1-mrna-28199
Rhizophoraceae	Ceriops tagal	1	nbisL1-mrna-947
Rhizophoraceae	Ceriops zippeliana	1	nbisL1-mrna-7787
Rhizophoraceae	Kandelia candel	1	evm.TU.utg000023l.236
Rhizophoraceae	Kandelia obovata	1	Maker00019035
Rhizophoraceae	Rhizophora apiculata	12	nbisL1-mrna-12310, nbisL1-mrna-12311, nbisL1-mrna-12330 ... nbisL1-mrna-12331, nbisL1-mrna-12332, nbisL1-mrna-12333, nbisL1-mrna-12336, nbisL1-mrna-12338, nbisL1-mrna-12339, nbisL1-mrna-12340, nbisL1-mrna-13324, nbisL1-mrna-21725
Rhizophoraceae	Rhizophora mangle	1	nbisL1-mrna-10476
Salicaceae	Populus euphratica	2	populus_peu02672, populus_peu02721
Solanaceae	Lycium barbarum	1	gene-LOC132641725
Solanaceae	Solanum chilense	1	SOLCI004060600
Solanaceae	Solanum pennellii	1	gene-LOC107019819
Tamaricaceae	Reaumuria soongarica	1	STRG.19293_chr07_-
Tamaricaceae	Tamarix chinensis	1	TC08G2286
Zosteraceae	Zostera marina	2	Zosma01g23290.v3.1, Zosma07g00570.v3.1