Basic Information
Locus ID:
CQ.Regalona.r1.9AG0015370
Species & Taxonomic ID:
Chenopodium quinoa & 63459
Genome Assembly:
GCA_040571445.1
Description:
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
Maps and Mapping Data
| Chromosome | Start | End | Strand | ID |
|---|---|---|---|---|
| chr9A | 49949655 | 49958498 | + | CQ.Regalona.r1.9AG0015370 |
Protein Data
Protein Properties:
| Theoretical pI | Molecular Weight | Instability Index | Aliphatic Index | GRAVY |
|---|---|---|---|---|
| 5.79 | 50,690.30 Da | 40.86 | 97.64 | 0.04 |
Protein Domain:
| Category | ID | Description | Start | End | Evalue/Score | InterPro ID |
|---|---|---|---|---|---|---|
| Pfam | PF00180 | Isocitrate/isopropylmalate dehydrogenase | 136 | 455 | 4.0E-124 | IPR024084 |
| SUPERFAMILY | SSF53659 | Isocitrate/Isopropylmalate dehydrogenase-like | 47 | 78 | 1.46E-5 | - |
| SUPERFAMILY | SSF53659 | Isocitrate/Isopropylmalate dehydrogenase-like | 134 | 458 | 3.22E-105 | - |
| Gene3D | G3DSA:3.40.718.10 | Isopropylmalate Dehydrogenase | 40 | 90 | 1.2E-5 | - |
| Gene3D | G3DSA:3.40.718.10 | Isopropylmalate Dehydrogenase | 115 | 466 | 1.4E-121 | - |
| SMART | SM01329 | Iso_dh_2 | 52 | 455 | 1.5E-180 | IPR024084 |
| TIGRFAM | TIGR00169 | leuB: 3-isopropylmalate dehydrogenase | 134 | 455 | 3.2E-142 | IPR004429 |
| ProSitePatterns | PS00470 | Isocitrate and isopropylmalate dehydrogenases signature. | 346 | 365 | - | IPR019818 |
| Hamap | MF_01033 | 3-isopropylmalate dehydrogenase [leuB]. | 51 | 459 | 48.335609 | IPR004429 |
Gene Ontology
Biological Process:
KEGG Pathway
Pathway:
ko00290 (Valine, leucine and isoleucine biosynthesis)
map00290 (Valine, leucine and isoleucine biosynthesis)
ko00660 (C5-Branched dibasic acid metabolism)
map00660 (C5-Branched dibasic acid metabolism)
ko01100 (Metabolic pathways)
map01100 (Metabolic pathways)
ko01110 (Biosynthesis of secondary metabolites)
map01110 (Biosynthesis of secondary metabolites)
ko01210 (2-Oxocarboxylic acid metabolism)
map01210 (2-Oxocarboxylic acid metabolism)
ko01230 (Biosynthesis of amino acids)
map01230 (Biosynthesis of amino acids)
Module:
Best hit
| Source | Best Hit ID | Description | E-value |
|---|---|---|---|
| TAIR | AT1G80560.1 | isopropylmalate dehydrogenase 2. The AtIMD2 is one out of 3 genes encoding the enzyme 3-isopropylmalate dehydrogenase involved in leucine biosynthesis in Arabidopsis. Its subcellular location has been targeted to plastids. | 0 |
| RefSeq | XP_021731756.1 | 3-isopropylmalate dehydrogenase 2, chloroplastic-like [Chenopodium quinoa] | 0 |
| P29102 | 3-isopropylmalate dehydrogenase, chloroplastic OS=Brassica napus OX=3708 PE=2 SV=1 | 0 | |
| TrEMBL | A0A803LE56 | 3-isopropylmalate dehydrogenase OS=Chenopodium quinoa OX=63459 PE=3 SV=1 | 0 |
Expression
| BioProject | Accession | TPM | Cultivar | Tissue | Development Stage | Sample Name | Description |
|---|---|---|---|---|---|---|---|
| No sample metadata found. | |||||||
Network
No network data available for this species.
Orthology
| Family | Species | Count | Orthologous Genes |
|---|---|---|---|
| Acanthaceae | Avicennia marina | 2 | jg18287, jg528 |
| Aizoaceae | Mesembryanthemum crystallinum | 2 | gene_25751, gene_26229 |
| Amaranthaceae | Atriplex hortensis | 1 | Ah010419 |
| Amaranthaceae | Beta vulgaris | 1 | BVRB_9g219010 |
| Amaranthaceae | Salicornia bigelovii | 3 | Sbi_jg11636, Sbi_jg46763, Sbi_jg46764 |
| Amaranthaceae | Salicornia europaea | 1 | Seu_jg20890 |
| Amaranthaceae | Suaeda aralocaspica | 1 | GOSA_00005123 |
| Amaranthaceae | Suaeda glauca | 3 | Sgl56347, Sgl61180, Sgl61877 |
| Amaranthaceae | Chenopodium album | 3 | gene:ENSEOMG00000018016, gene:ENSEOMG00000038486 ... |
| Amaranthaceae | Chenopodium quinoa | 2 | CQ.Regalona.r1.7BG0009150, CQ.Regalona.r1.9AG0015370 |
| Anacardiaceae | Pistacia vera | 2 | pistato.v30129510, pistato.v30129560 |
| Apiaceae | Apium graveolens | 1 | Ag9G01190 |
| Arecaceae | Cocos nucifera | 1 | COCNU_16G001040 |
| Arecaceae | Phoenix dactylifera | 1 | gene-LOC103714417 |
| Asparagaceae | Asparagus officinalis | 1 | AsparagusV1_Unassigned.879.V1.1 |
| Asteraceae | Flaveria trinervia | 1 | Ftri16G21300 |
| Brassicaceae | Arabidopsis thaliana | 4 | AT1G31180.1, AT1G80555.1, AT1G80560.1, AT5G14200.1 |
| Brassicaceae | Eutrema salsugineum | 2 | Thhalv10013695m.g.v1.0, Thhalv10018649m.g.v1.0 |
| Brassicaceae | Schrenkiella parvula | 5 | Sp5g29930.v2.2, Sp5g35220.v2.2, Sp5g35230.v2.2 ... |
| Brassicaceae | Brassica nigra | 6 | BniB05g024330.2N, BniB05g075620.2N, BniB05g075630.2N ... |
| Casuarinaceae | Casuarina equisetifolia | 2 | Ceq02G0369, Ceq02G0401 |
| Casuarinaceae | Casuarina glauca | 1 | Cgl02G0390 |
| Cymodoceaceae | Cymodocea nodosa | 2 | gene.Cymno02g16450, gene.Cymno02g16760 |
| Dunaliellaceae | Dunaliella salina | 1 | Dusal.0239s00002.v1.0 |
| Hydrocharitaceae | Thalassia testudinum | 1 | gene.Thate04g18480 |
| Nitrariaceae | Nitraria sibirica | 1 | evm.TU.LG03.1966 |
| Plantaginaceae | Plantago ovata | 1 | Pov_00034531 |
| Plumbaginaceae | Limonium bicolor | 2 | Lb7G32910, Lb7G32911 |
| Poaceae | Echinochloa crus-galli | 3 | AH09.2783, BH09.3019, CH09.3186 |
| Poaceae | Eleusine coracana subsp. coracana | 2 | gene-QOZ80_4AG0298620, gene-QOZ80_4BG0329320 |
| Poaceae | Hordeum vulgare | 1 | HORVU.MOREX.r3.2HG0214780.1 |
| Poaceae | Lolium multiflorum | 3 | gene-QYE76_011123, gene-QYE76_017999, gene-QYE76_049572 |
| Poaceae | Oryza coarctata | 2 | Oco05G019360, Oco06G020270 |
| Poaceae | Oryza sativa | 1 | LOC_Os03g45320.1 |
| Poaceae | Paspalum vaginatum | 1 | gene-BS78_06G291900 |
| Poaceae | Puccinellia tenuiflora | 2 | Pt_Chr0206518, Pt_Chr0306994 |
| Poaceae | Sporobolus alterniflorus | 4 | Chr05G015640, Chr23G000380, Chr25G000320, Chr26G018810 |
| Poaceae | Thinopyrum elongatum | 2 | Tel2E01G995400, Tel3E01G007700 |
| Poaceae | Triticum dicoccoides | 5 | gene_TRIDC1BG004300, gene_TRIDC2AG080070 ... |
| Poaceae | Triticum aestivum | 6 | TraesCS2A02G577600.1, TraesCS2B02G609800.1 ... |
| Poaceae | Zea mays | 3 | Zm00001eb013290_P001, Zm00001eb076030_P001 ... |
| Poaceae | Zoysia japonica | 1 | nbis-gene-18097 |
| Poaceae | Zoysia macrostachya | 2 | Zma_g22277, Zma_g27771 |
| Portulacaceae | Portulaca oleracea | 2 | evm.TU.LG07.1807, evm.TU.LG15.1362 |
| Posidoniaceae | Posidonia oceanica | 3 | gene.Posoc04g05940, gene.Posoc04g05950, gene.Posoc08g09870 |
| Rhizophoraceae | Bruguiera sexangula | 1 | evm.TU.Scaffold_18_RagTag.303 |
| Rhizophoraceae | Carallia pectinifolia | 1 | nbisL1-mrna-28199 |
| Rhizophoraceae | Ceriops tagal | 1 | nbisL1-mrna-947 |
| Rhizophoraceae | Ceriops zippeliana | 1 | nbisL1-mrna-7787 |
| Rhizophoraceae | Kandelia candel | 1 | evm.TU.utg000023l.236 |
| Rhizophoraceae | Kandelia obovata | 1 | Maker00019035 |
| Rhizophoraceae | Rhizophora apiculata | 12 | nbisL1-mrna-12310, nbisL1-mrna-12311, nbisL1-mrna-12330 ... |
| Rhizophoraceae | Rhizophora mangle | 1 | nbisL1-mrna-10476 |
| Salicaceae | Populus euphratica | 2 | populus_peu02672, populus_peu02721 |
| Solanaceae | Lycium barbarum | 1 | gene-LOC132641725 |
| Solanaceae | Solanum chilense | 1 | SOLCI004060600 |
| Solanaceae | Solanum pennellii | 1 | gene-LOC107019819 |
| Tamaricaceae | Reaumuria soongarica | 1 | STRG.19293_chr07_- |
| Tamaricaceae | Tamarix chinensis | 1 | TC08G2286 |
| Zosteraceae | Zostera marina | 2 | Zosma01g23290.v3.1, Zosma07g00570.v3.1 |