Basic Information
Locus ID:
COCNU_12G004560
Species & Taxonomic ID:
Cocos nucifera & 13894
Genome Assembly:
GCA_008124465.1
Description:
2-isopropylmalate synthase
Maps and Mapping Data
| Chromosome | Start | End | Strand | ID |
|---|---|---|---|---|
| chr12 | 30043471 | 30077329 | - | COCNU_12G004560 |
Protein Data
Protein Properties:
| Theoretical pI | Molecular Weight | Instability Index | Aliphatic Index | GRAVY |
|---|---|---|---|---|
| 6.31 | 70,290.32 Da | 50.32 | 88.96 | -0.16 |
Protein Domain:
| Category | ID | Description | Start | End | Evalue/Score | InterPro ID |
|---|---|---|---|---|---|---|
| CDD | cd07940 | DRE_TIM_IPMS | 88 | 367 | 1.39949E-176 | - |
| Pfam | PF00682 | HMGL-like | 86 | 365 | 4.5E-94 | IPR000891 |
| Pfam | PF08502 | LeuA allosteric (dimerisation) domain | 481 | 625 | 1.7E-35 | IPR013709 |
| SUPERFAMILY | SSF51569 | Aldolase | 85 | 383 | 1.83E-90 | - |
| SUPERFAMILY | SSF110921 | 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain | 517 | 624 | 2.22E-16 | IPR036230 |
| Gene3D | G3DSA:3.20.20.70 | Aldolase class I | 83 | 371 | 1.6E-98 | IPR013785 |
| Gene3D | G3DSA:3.30.160.270 | - | 506 | 625 | 3.8E-25 | IPR036230 |
| Gene3D | G3DSA:1.10.238.260 | - | 372 | 490 | 8.9E-34 | - |
| SMART | SM00917 | LeuA_dimer_2 | 480 | 625 | 1.4E-28 | IPR013709 |
| TIGRFAM | TIGR00973 | leuA_bact: 2-isopropylmalate synthase | 86 | 622 | 3.2E-191 | IPR005671 |
| ProSiteProfiles | PS50991 | Pyruvate carboxyltransferase domain. | 86 | 359 | 42.491528 | IPR000891 |
| ProSitePatterns | PS00815 | Alpha-isopropylmalate and homocitrate synthases signature 1. | 93 | 109 | - | IPR002034 |
Gene Ontology
Biological Process:
KEGG Pathway
Pathway:
ko00290 (Valine, leucine and isoleucine biosynthesis)
map00290 (Valine, leucine and isoleucine biosynthesis)
ko00620 (Pyruvate metabolism)
map00620 (Pyruvate metabolism)
ko01100 (Metabolic pathways)
map01100 (Metabolic pathways)
ko01110 (Biosynthesis of secondary metabolites)
map01110 (Biosynthesis of secondary metabolites)
ko01210 (2-Oxocarboxylic acid metabolism)
map01210 (2-Oxocarboxylic acid metabolism)
ko01230 (Biosynthesis of amino acids)
map01230 (Biosynthesis of amino acids)
Best hit
| Source | Best Hit ID | Description | E-value |
|---|---|---|---|
| TAIR | AT1G74040.1 | 2-isopropylmalate synthase 1. Encodes an active Arabidopsis isopropylmalate synthase IPMS2. Involved in leucine biosynthesis. Do not participate in the chain elongation of glucosinolates. Expressed constitutively throughout the plant. Loss of IPMS2 can be compensated by a second isopropylmalate synthase gene IPMS1 (At1g18500). | 0 |
| RefSeq | XP_010931990.1 | 2-isopropylmalate synthase A [Elaeis guineensis] | 0 |
| O04973 | 2-isopropylmalate synthase A OS=Solanum pennellii OX=28526 GN=IPMSA PE=2 SV=1 | 0 | |
| TrEMBL | A0A8K0IRV7 | 2-isopropylmalate synthase OS=Cocos nucifera OX=13894 GN=COCNU_12G004560 PE=3 SV=1 | 0 |
Expression
| BioProject | Accession | TPM | Cultivar | Tissue | Development Stage | Sample Name | Description |
|---|---|---|---|---|---|---|---|
| No sample metadata found. | |||||||
Orthology
| Family | Species | Count | Orthologous Genes |
|---|---|---|---|
| Acanthaceae | Avicennia marina | 3 | jg10976, jg10977, jg5907 |
| Aizoaceae | Mesembryanthemum crystallinum | 2 | gene_15767, gene_19447 |
| Amaranthaceae | Atriplex hortensis | 2 | Ah019627, Ah019628 |
| Amaranthaceae | Beta vulgaris | 2 | BVRB_3g058810, BVRB_3g058820 |
| Amaranthaceae | Salicornia bigelovii | 2 | Sbi_jg38490, Sbi_jg6594 |
| Amaranthaceae | Salicornia europaea | 1 | Seu_jg15332 |
| Amaranthaceae | Suaeda aralocaspica | 2 | GOSA_00006427, GOSA_00006428 |
| Amaranthaceae | Suaeda glauca | 6 | Sgl01897, Sgl01898, Sgl07038, Sgl07039, Sgl44504, Sgl49273 |
| Amaranthaceae | Chenopodium album | 3 | gene:ENSEOMG00000011743, gene:ENSEOMG00000030441 ... |
| Amaranthaceae | Chenopodium quinoa | 2 | CQ.Regalona.r1.3AG0011030, CQ.Regalona.r1.3BG0011260 |
| Anacardiaceae | Pistacia vera | 1 | pistato.v30243490 |
| Apiaceae | Apium graveolens | 1 | Ag5G02859 |
| Arecaceae | Cocos nucifera | 1 | COCNU_12G004560 |
| Arecaceae | Phoenix dactylifera | 1 | gene-LOC103705082 |
| Asparagaceae | Asparagus officinalis | 4 | AsparagusV1_04.1953.V1.1, AsparagusV1_04.1955.V1.1 ... |
| Asteraceae | Flaveria trinervia | 2 | Ftri11G03059, Ftri12G07723 |
| Brassicaceae | Arabidopsis thaliana | 4 | AT1G18500.1, AT1G74040.1, AT5G23010.1, AT5G23020.1 |
| Brassicaceae | Eutrema salsugineum | 5 | Thhalv10003976m.g.v1.0, Thhalv10004072m.g.v1.0 ... |
| Brassicaceae | Schrenkiella parvula | 5 | Sp1g16450.v2.2, Sp2g24100.v2.2, Sp2g24110.v2.2 ... |
| Brassicaceae | Brassica nigra | 8 | BniB02g076300.2N, BniB02g076310.2N, BniB03g028050.2N ... |
| Casuarinaceae | Casuarina equisetifolia | 2 | Ceq06G2205, Ceq09G0942 |
| Casuarinaceae | Casuarina glauca | 2 | Cgl06G2325, Cgl09G1024 |
| Cymodoceaceae | Cymodocea nodosa | 1 | gene.Cymno05g02310 |
| Dunaliellaceae | Dunaliella salina | 2 | Dusal.0217s00013.v1.0, Dusal.0217s00014.v1.0 |
| Hydrocharitaceae | Thalassia testudinum | 1 | gene.Thate08g08470 |
| Nitrariaceae | Nitraria sibirica | 4 | evm.TU.LG02.2457, evm.TU.LG11.123, evm.TU.LG11.124 ... |
| Plantaginaceae | Plantago ovata | 2 | Pov_00023467, Pov_00026884 |
| Plumbaginaceae | Limonium bicolor | 1 | Lb7G33591 |
| Poaceae | Echinochloa crus-galli | 10 | AH02.813, AH04.240, AH05.159, BH02.108, BH02.135, BH04.237 ... |
| Poaceae | Eleusine coracana subsp. coracana | 4 | gene-QOZ80_5AG0380830, gene-QOZ80_5BG0427930 ... |
| Poaceae | Hordeum vulgare | 1 | HORVU.MOREX.r3.5HG0460900.1 |
| Poaceae | Lolium multiflorum | 3 | gene-QYE76_003279, gene-QYE76_003349, gene-QYE76_052410 |
| Poaceae | Oryza coarctata | 4 | Oco21G000770, Oco22G001620, Oco23G001530, Oco24G000960 |
| Poaceae | Oryza sativa | 2 | LOC_Os11g04670.1, LOC_Os12g04440.1 |
| Poaceae | Paspalum vaginatum | 1 | gene-BS78_05G039500 |
| Poaceae | Puccinellia tenuiflora | 3 | Pt_Chr0500049, Pt_Chr0703001, Pt_Chr0703081 |
| Poaceae | Sporobolus alterniflorus | 2 | Chr16G009170, Chr17G008190 |
| Poaceae | Thinopyrum elongatum | 1 | Tel5E01G238500 |
| Poaceae | Triticum dicoccoides | 3 | gene_TRIDC5AG022230, gene_TRIDC5BG023720 ... |
| Poaceae | Triticum aestivum | 4 | TraesCS5A02G131300.1, TraesCS5B02G133500.1 ... |
| Poaceae | Zea mays | 4 | Zm00001eb093160_P001, Zm00001eb196510_P001 ... |
| Poaceae | Zoysia japonica | 2 | nbis-gene-27033, nbis-gene-51079 |
| Poaceae | Zoysia macrostachya | 1 | Zma_g18398 |
| Portulacaceae | Portulaca oleracea | 4 | evm.TU.LG04.828, evm.TU.LG05.2106, evm.TU.LG06.1512 ... |
| Posidoniaceae | Posidonia oceanica | 1 | gene.Posoc01g05010 |
| Rhizophoraceae | Bruguiera sexangula | 1 | evm.TU.Scaffold_3_RagTag.1457 |
| Rhizophoraceae | Carallia pectinifolia | 1 | nbisL1-mrna-1766 |
| Rhizophoraceae | Ceriops tagal | 1 | nbisL1-mrna-1548 |
| Rhizophoraceae | Ceriops zippeliana | 1 | nbisL1-mrna-2684 |
| Rhizophoraceae | Kandelia candel | 1 | evm.TU.utg000019l.366 |
| Rhizophoraceae | Kandelia obovata | 1 | Maker00001810 |
| Rhizophoraceae | Rhizophora apiculata | 1 | nbisL1-mrna-12297 |
| Rhizophoraceae | Rhizophora mangle | 1 | nbisL1-mrna-12819 |
| Salicaceae | Populus euphratica | 1 | populus_peu13845 |
| Solanaceae | Lycium barbarum | 2 | gene-LOC132609321, gene-LOC132643462 |
| Solanaceae | Solanum chilense | 3 | SOLCI004281200, SOLCI006467400, SOLCI006806900 |
| Solanaceae | Solanum pennellii | 5 | gene-LOC107023302, gene-LOC107026725, gene-LOC107026726 ... |
| Tamaricaceae | Reaumuria soongarica | 1 | STRG.14313_chr08_- |
| Tamaricaceae | Tamarix chinensis | 1 | TC12G1851 |
| Zosteraceae | Zostera marina | 2 | Zosma02g23460.v3.1, Zosma03g21940.v3.1 |