Basic Information
Locus ID:
BniB03g030530.2N
Species & Taxonomic ID:
Brassica nigra & 3710
Genome Assembly:
N100
Description:
protease subunit of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes such as photomorphogenesis and auxin and jasmonate responses. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of the SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF. In the complex, it probably acts as the catalytic center that mediates the cleavage of Nedd8 from cullins. It however has no metalloprotease activity by itself and requires the other subunits of the CSN complex (By similarity). The CSN complex is involved in repression of photomorphogenesis in darkness by regulating the activity of COP1-containing Ubl ligase complexes. The complex is also required for degradation of PSIAA6 by regulating the activity of the Ubl ligase SCF-TIR complex. Involved in CSN's deneddylation derubylation activity. Required for the deneddylation of all cullins. Essential for the structural integrity of the CSN holocomplex
Maps and Mapping Data
| Chromosome | Start | End | Strand | ID |
|---|---|---|---|---|
| B3 | 14255998 | 14258101 | - | BniB03g030530.2N |
Protein Data
Protein Properties:
| Theoretical pI | Molecular Weight | Instability Index | Aliphatic Index | GRAVY |
|---|---|---|---|---|
| 5.48 | 39,676.24 Da | 42.55 | 82.39 | -0.42 |
Protein Domain:
| Category | ID | Description | Start | End | Evalue/Score | InterPro ID |
|---|---|---|---|---|---|---|
| CDD | cd08069 | MPN_RPN11_CSN5 | 47 | 319 | 3.37668E-150 | - |
| Pfam | PF18323 | Cop9 signalosome subunit 5 C-terminal domain | 254 | 334 | 1.6E-23 | IPR040961 |
| Pfam | PF01398 | JAB1/Mov34/MPN/PAD-1 ubiquitin protease | 55 | 166 | 3.4E-34 | IPR000555 |
| SUPERFAMILY | SSF102712 | JAB1/MPN domain | 57 | 191 | 9.55E-14 | - |
| Gene3D | G3DSA:3.40.140.10 | Cytidine Deaminase, domain 2 | 1 | 260 | 3.9E-113 | - |
| SMART | SM00232 | pad1_6 | 57 | 194 | 1.1E-47 | IPR000555 |
| ProSiteProfiles | PS50249 | MPN domain profile. | 58 | 195 | 33.409897 | IPR037518 |
| MobiDBLite | mobidb-lite | consensus disorder prediction | 334 | 355 | - | - |
Gene Ontology
KEGG Pathway
Best hit
| Source | Best Hit ID | Description | E-value |
|---|---|---|---|
| TAIR | AT1G22920.1 | COP9 signalosome 5A. AJH1 encodes a protein similar to JAB1, a specific mammalian coactivator of AP-1 transcription. Encodes a subunit of the COP9 complex that is involved in protein deneddylation. Plants with mutations in CSN5A and CSN5B have a de-etiolated phenotype. | 0 |
| RefSeq | XP_013705959.1 | COP9 signalosome complex subunit 5a [Brassica napus] | 0 |
| Q8LAZ7 | COP9 signalosome complex subunit 5a OS=Arabidopsis thaliana OX=3702 GN=CSN5A PE=1 SV=2 | 0 | |
| TrEMBL | A0A397YLI3 | MPN domain-containing protein OS=Brassica campestris OX=3711 GN=BRARA_G01020 PE=3 SV=1 | 0 |
Expression
| BioProject | Accession | TPM | Cultivar | Tissue | Development Stage | Sample Name | Description |
|---|---|---|---|---|---|---|---|
| No sample metadata found. | |||||||
Orthology
| Family | Species | Count | Orthologous Genes |
|---|---|---|---|
| Acanthaceae | Avicennia marina | 1 | jg7782 |
| Aizoaceae | Mesembryanthemum crystallinum | 1 | gene_13106 |
| Amaranthaceae | Atriplex hortensis | 1 | Ah034416 |
| Amaranthaceae | Beta vulgaris | 1 | BVRB_2g033490 |
| Amaranthaceae | Salicornia bigelovii | 2 | Sbi_jg20473, Sbi_jg23330 |
| Amaranthaceae | Salicornia europaea | 1 | Seu_jg17103 |
| Amaranthaceae | Suaeda aralocaspica | 1 | GOSA_00009100 |
| Amaranthaceae | Suaeda glauca | 2 | Sgl63561, Sgl68054 |
| Amaranthaceae | Chenopodium album | 3 | gene:ENSEOMG00000017221, gene:ENSEOMG00000020679 ... |
| Amaranthaceae | Chenopodium quinoa | 2 | CQ.Regalona.r1.2AG0013420, CQ.Regalona.r1.2BG0015440 |
| Anacardiaceae | Pistacia vera | 1 | pistato.v30251900 |
| Apiaceae | Apium graveolens | 1 | Ag8G01268 |
| Arecaceae | Cocos nucifera | 2 | COCNU_01G003770, contig69480108G000010 |
| Arecaceae | Phoenix dactylifera | 2 | gene-LOC103718036, gene-LOC103721529 |
| Asparagaceae | Asparagus officinalis | 1 | AsparagusV1_03.1428.V1.1 |
| Asteraceae | Flaveria trinervia | 1 | Ftri13G33348 |
| Brassicaceae | Arabidopsis thaliana | 2 | AT1G22920.1, AT1G71230.1 |
| Brassicaceae | Eutrema salsugineum | 2 | Thhalv10008042m.g.v1.0, Thhalv10018788m.g.v1.0 |
| Brassicaceae | Schrenkiella parvula | 2 | Sp1g20380.v2.2, Sp5g26420.v2.2 |
| Brassicaceae | Brassica nigra | 2 | BniB03g030530.2N, BniB04g038190.2N |
| Casuarinaceae | Casuarina equisetifolia | 1 | Ceq04G2188 |
| Casuarinaceae | Casuarina glauca | 1 | Cgl04G2382 |
| Cymodoceaceae | Cymodocea nodosa | 1 | gene.Cymno06g06670 |
| Dunaliellaceae | Dunaliella salina | 1 | Dusal.0004s00011.v1.0 |
| Hydrocharitaceae | Thalassia testudinum | 1 | gene.Thate03g22590 |
| Nitrariaceae | Nitraria sibirica | 1 | evm.TU.LG07.1603 |
| Plantaginaceae | Plantago ovata | 1 | Pov_00028703 |
| Plumbaginaceae | Limonium bicolor | 1 | Lb1G05034 |
| Poaceae | Echinochloa crus-galli | 3 | AH09.2545, BH09.2778, CH09.2976 |
| Poaceae | Eleusine coracana subsp. coracana | 2 | gene-QOZ80_4AG0301140, gene-QOZ80_4BG0331910 |
| Poaceae | Hordeum vulgare | 5 | HORVU.MOREX.r3.2HG0203060.1, HORVU.MOREX.r3.3HG0238330.1 ... |
| Poaceae | Lolium multiflorum | 1 | gene-QYE76_046854 |
| Poaceae | Oryza coarctata | 2 | Oco07G017840, Oco08G017230 |
| Poaceae | Oryza sativa | 1 | LOC_Os04g56070.1 |
| Poaceae | Paspalum vaginatum | 1 | gene-BS78_06G264100 |
| Poaceae | Sporobolus alterniflorus | 4 | Chr23G002160, Chr25G001700, Chr26G017210, Chr30G001710 |
| Poaceae | Thinopyrum elongatum | 1 | Tel2E01G856000 |
| Poaceae | Triticum dicoccoides | 2 | gene_TRIDC2AG071050, gene_TRIDC2BG076780 |
| Poaceae | Triticum aestivum | 2 | TraesCS2A02G504600.1, TraesCS2D02G505300.1 |
| Poaceae | Zea mays | 1 | Zm00001eb068020_P001 |
| Poaceae | Zoysia japonica | 1 | nbis-gene-23062 |
| Poaceae | Zoysia macrostachya | 1 | Zma_g20584 |
| Portulacaceae | Portulaca oleracea | 2 | evm.TU.LG07.831, evm.TU.LG15.101 |
| Posidoniaceae | Posidonia oceanica | 1 | gene.Posoc03g14700 |
| Rhizophoraceae | Bruguiera sexangula | 1 | evm.TU.Scaffold_10_RagTag.977 |
| Rhizophoraceae | Carallia pectinifolia | 1 | nbisL1-mrna-13512 |
| Rhizophoraceae | Ceriops tagal | 1 | nbisL1-mrna-10845 |
| Rhizophoraceae | Ceriops zippeliana | 1 | nbisL1-mrna-9215 |
| Rhizophoraceae | Kandelia candel | 1 | evm.TU.utg000004l.251 |
| Rhizophoraceae | Kandelia obovata | 1 | Maker00004104 |
| Rhizophoraceae | Rhizophora apiculata | 1 | nbisL1-mrna-3690 |
| Rhizophoraceae | Rhizophora mangle | 1 | nbisL1-mrna-7726 |
| Salicaceae | Populus euphratica | 2 | populus_peu04590, populus_peu13073 |
| Solanaceae | Lycium barbarum | 1 | gene-LOC132603052 |
| Solanaceae | Solanum chilense | 2 | SOLCI000120000, SOLCI006509000 |
| Solanaceae | Solanum pennellii | 2 | gene-LOC107004781, gene-LOC107023832 |
| Tamaricaceae | Reaumuria soongarica | 1 | gene_13360 |
| Tamaricaceae | Tamarix chinensis | 1 | TC11G1517 |
| Zosteraceae | Zostera marina | 1 | Zosma03g19520.v3.1 |