Basic Information
Locus ID:
BH04.237
Species & Taxonomic ID:
Echinochloa crus-galli & 90397
Genome Assembly:
GWHBDNR00000000
Description:
2-isopropylmalate synthase
Maps and Mapping Data
| Chromosome | Start | End | Strand | ID |
|---|---|---|---|---|
| BH04 | 1896588 | 1905400 | + | BH04.237 |
Protein Data
Protein Properties:
| Theoretical pI | Molecular Weight | Instability Index | Aliphatic Index | GRAVY |
|---|---|---|---|---|
| 5.59 | 144,844.11 Da | 49.89 | 76.76 | -0.36 |
Protein Domain:
| Category | ID | Description | Start | End | Evalue/Score | InterPro ID |
|---|---|---|---|---|---|---|
| CDD | cd07940 | DRE_TIM_IPMS | 95 | 374 | 7.40912E-166 | - |
| CDD | cd16454 | RING-H2_PA-TM-RING | 1136 | 1181 | 1.88452E-16 | - |
| Pfam | PF13639 | Ring finger domain | 1136 | 1181 | 4.7E-11 | IPR001841 |
| Pfam | PF08502 | LeuA allosteric (dimerisation) domain | 472 | 615 | 2.4E-32 | IPR013709 |
| Pfam | PF17123 | RING-like zinc finger | 757 | 785 | 1.2E-10 | IPR001841 |
| Pfam | PF00682 | HMGL-like | 93 | 371 | 4.9E-89 | IPR000891 |
| SUPERFAMILY | SSF51569 | Aldolase | 90 | 390 | 4.58E-88 | - |
| SUPERFAMILY | SSF57850 | RING/U-box | 753 | 794 | 1.38E-12 | - |
| SUPERFAMILY | SSF57850 | RING/U-box | 1133 | 1187 | 1.64E-16 | - |
| SUPERFAMILY | SSF110921 | 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain | 506 | 615 | 7.32E-15 | IPR036230 |
| Gene3D | G3DSA:3.30.160.270 | - | 495 | 616 | 2.3E-21 | IPR036230 |
| Gene3D | G3DSA:3.30.40.10 | Zinc/RING finger domain, C3HC4 (zinc finger) | 1103 | 1185 | 6.3E-18 | IPR013083 |
| Gene3D | G3DSA:1.10.238.260 | - | 380 | 491 | 7.9E-35 | - |
| Gene3D | G3DSA:3.30.40.10 | Zinc/RING finger domain, C3HC4 (zinc finger) | 733 | 796 | 2.3E-13 | IPR013083 |
| Gene3D | G3DSA:3.20.20.70 | Aldolase class I | 88 | 376 | 4.0E-94 | IPR013785 |
| SMART | SM00184 | ring_2 | 1137 | 1180 | 1.0E-8 | IPR001841 |
| SMART | SM00184 | ring_2 | 758 | 996 | 0.015 | IPR001841 |
| SMART | SM00917 | LeuA_dimer_2 | 471 | 616 | 8.4E-25 | IPR013709 |
| TIGRFAM | TIGR00973 | leuA_bact: 2-isopropylmalate synthase | 93 | 613 | 8.5E-194 | IPR005671 |
| ProSiteProfiles | PS50089 | Zinc finger RING-type profile. | 758 | 788 | 8.594486 | IPR001841 |
| ProSiteProfiles | PS50089 | Zinc finger RING-type profile. | 1137 | 1181 | 11.95817 | IPR001841 |
| ProSiteProfiles | PS50991 | Pyruvate carboxyltransferase domain. | 93 | 366 | 41.87431 | IPR000891 |
| ProSitePatterns | PS00815 | Alpha-isopropylmalate and homocitrate synthases signature 1. | 100 | 116 | - | IPR002034 |
| Hamap | MF_01025 | 2-isopropylmalate synthase [leuA]. | 90 | 625 | 38.855251 | IPR005671 |
| MobiDBLite | mobidb-lite | consensus disorder prediction | 1 | 35 | - | - |
| MobiDBLite | mobidb-lite | consensus disorder prediction | 1006 | 1065 | - | - |
| MobiDBLite | mobidb-lite | consensus disorder prediction | 849 | 864 | - | - |
| MobiDBLite | mobidb-lite | consensus disorder prediction | 801 | 883 | - | - |
| MobiDBLite | mobidb-lite | consensus disorder prediction | 806 | 826 | - | - |
| MobiDBLite | mobidb-lite | consensus disorder prediction | 1007 | 1030 | - | - |
| MobiDBLite | mobidb-lite | consensus disorder prediction | 1 | 33 | - | - |
| MobiDBLite | mobidb-lite | consensus disorder prediction | 827 | 844 | - | - |
Gene Ontology
Biological Process:
KEGG Pathway
Pathway:
ko00290 (Valine, leucine and isoleucine biosynthesis)
map00290 (Valine, leucine and isoleucine biosynthesis)
ko00620 (Pyruvate metabolism)
map00620 (Pyruvate metabolism)
ko01100 (Metabolic pathways)
map01100 (Metabolic pathways)
ko01110 (Biosynthesis of secondary metabolites)
map01110 (Biosynthesis of secondary metabolites)
ko01210 (2-Oxocarboxylic acid metabolism)
map01210 (2-Oxocarboxylic acid metabolism)
ko01230 (Biosynthesis of amino acids)
map01230 (Biosynthesis of amino acids)
Best hit
| Source | Best Hit ID | Description | E-value |
|---|---|---|---|
| TAIR | AT1G18500.1 | methylthioalkylmalate synthase-like 4. Encodes an active Arabidopsis isopropylmalate synthase IPMS1. Involved in leucine biosynthesis. Do not participate in the chain elongation of glucosinolates. Expressed constitutively throughout the plant. Loss of IPMS1 can be compensated by a second isopropylmalate synthase gene IPMS2 (At1g74040). | 1.22E-266 |
| RefSeq | XP_004978642.1 | 2-isopropylmalate synthase A [Setaria italica] | 0 |
| O04973 | 2-isopropylmalate synthase A OS=Solanum pennellii OX=28526 GN=IPMSA PE=2 SV=1 | 5.07E-269 | |
| TrEMBL | A0A835E6X4 | 2-isopropylmalate synthase OS=Digitaria exilis OX=1010633 GN=HU200_054390 PE=4 SV=1 | 0 |
Expression
| BioProject | Accession | TPM | Cultivar | Tissue | Development Stage | Sample Name | Description |
|---|---|---|---|---|---|---|---|
| No sample metadata found. | |||||||
Orthology
| Family | Species | Count | Orthologous Genes |
|---|---|---|---|
| Acanthaceae | Avicennia marina | 3 | jg10976, jg10977, jg5907 |
| Aizoaceae | Mesembryanthemum crystallinum | 2 | gene_15767, gene_19447 |
| Amaranthaceae | Atriplex hortensis | 2 | Ah019627, Ah019628 |
| Amaranthaceae | Beta vulgaris | 2 | BVRB_3g058810, BVRB_3g058820 |
| Amaranthaceae | Salicornia bigelovii | 2 | Sbi_jg38490, Sbi_jg6594 |
| Amaranthaceae | Salicornia europaea | 1 | Seu_jg15332 |
| Amaranthaceae | Suaeda aralocaspica | 2 | GOSA_00006427, GOSA_00006428 |
| Amaranthaceae | Suaeda glauca | 6 | Sgl01897, Sgl01898, Sgl07038, Sgl07039, Sgl44504, Sgl49273 |
| Amaranthaceae | Chenopodium album | 3 | gene:ENSEOMG00000011743, gene:ENSEOMG00000030441 ... |
| Amaranthaceae | Chenopodium quinoa | 2 | CQ.Regalona.r1.3AG0011030, CQ.Regalona.r1.3BG0011260 |
| Anacardiaceae | Pistacia vera | 1 | pistato.v30243490 |
| Apiaceae | Apium graveolens | 1 | Ag5G02859 |
| Arecaceae | Cocos nucifera | 1 | COCNU_12G004560 |
| Arecaceae | Phoenix dactylifera | 1 | gene-LOC103705082 |
| Asparagaceae | Asparagus officinalis | 4 | AsparagusV1_04.1953.V1.1, AsparagusV1_04.1955.V1.1 ... |
| Asteraceae | Flaveria trinervia | 2 | Ftri11G03059, Ftri12G07723 |
| Brassicaceae | Arabidopsis thaliana | 4 | AT1G18500.1, AT1G74040.1, AT5G23010.1, AT5G23020.1 |
| Brassicaceae | Eutrema salsugineum | 5 | Thhalv10003976m.g.v1.0, Thhalv10004072m.g.v1.0 ... |
| Brassicaceae | Schrenkiella parvula | 5 | Sp1g16450.v2.2, Sp2g24100.v2.2, Sp2g24110.v2.2 ... |
| Brassicaceae | Brassica nigra | 8 | BniB02g076300.2N, BniB02g076310.2N, BniB03g028050.2N ... |
| Casuarinaceae | Casuarina equisetifolia | 2 | Ceq06G2205, Ceq09G0942 |
| Casuarinaceae | Casuarina glauca | 2 | Cgl06G2325, Cgl09G1024 |
| Cymodoceaceae | Cymodocea nodosa | 1 | gene.Cymno05g02310 |
| Dunaliellaceae | Dunaliella salina | 2 | Dusal.0217s00013.v1.0, Dusal.0217s00014.v1.0 |
| Hydrocharitaceae | Thalassia testudinum | 1 | gene.Thate08g08470 |
| Nitrariaceae | Nitraria sibirica | 4 | evm.TU.LG02.2457, evm.TU.LG11.123, evm.TU.LG11.124 ... |
| Plantaginaceae | Plantago ovata | 2 | Pov_00023467, Pov_00026884 |
| Plumbaginaceae | Limonium bicolor | 1 | Lb7G33591 |
| Poaceae | Echinochloa crus-galli | 10 | AH02.813, AH04.240, AH05.159, BH02.108, BH02.135, BH04.237 ... |
| Poaceae | Eleusine coracana subsp. coracana | 4 | gene-QOZ80_5AG0380830, gene-QOZ80_5BG0427930 ... |
| Poaceae | Hordeum vulgare | 1 | HORVU.MOREX.r3.5HG0460900.1 |
| Poaceae | Lolium multiflorum | 3 | gene-QYE76_003279, gene-QYE76_003349, gene-QYE76_052410 |
| Poaceae | Oryza coarctata | 4 | Oco21G000770, Oco22G001620, Oco23G001530, Oco24G000960 |
| Poaceae | Oryza sativa | 2 | LOC_Os11g04670.1, LOC_Os12g04440.1 |
| Poaceae | Paspalum vaginatum | 1 | gene-BS78_05G039500 |
| Poaceae | Puccinellia tenuiflora | 3 | Pt_Chr0500049, Pt_Chr0703001, Pt_Chr0703081 |
| Poaceae | Sporobolus alterniflorus | 2 | Chr16G009170, Chr17G008190 |
| Poaceae | Thinopyrum elongatum | 1 | Tel5E01G238500 |
| Poaceae | Triticum dicoccoides | 3 | gene_TRIDC5AG022230, gene_TRIDC5BG023720 ... |
| Poaceae | Triticum aestivum | 4 | TraesCS5A02G131300.1, TraesCS5B02G133500.1 ... |
| Poaceae | Zea mays | 4 | Zm00001eb093160_P001, Zm00001eb196510_P001 ... |
| Poaceae | Zoysia japonica | 2 | nbis-gene-27033, nbis-gene-51079 |
| Poaceae | Zoysia macrostachya | 1 | Zma_g18398 |
| Portulacaceae | Portulaca oleracea | 4 | evm.TU.LG04.828, evm.TU.LG05.2106, evm.TU.LG06.1512 ... |
| Posidoniaceae | Posidonia oceanica | 1 | gene.Posoc01g05010 |
| Rhizophoraceae | Bruguiera sexangula | 1 | evm.TU.Scaffold_3_RagTag.1457 |
| Rhizophoraceae | Carallia pectinifolia | 1 | nbisL1-mrna-1766 |
| Rhizophoraceae | Ceriops tagal | 1 | nbisL1-mrna-1548 |
| Rhizophoraceae | Ceriops zippeliana | 1 | nbisL1-mrna-2684 |
| Rhizophoraceae | Kandelia candel | 1 | evm.TU.utg000019l.366 |
| Rhizophoraceae | Kandelia obovata | 1 | Maker00001810 |
| Rhizophoraceae | Rhizophora apiculata | 1 | nbisL1-mrna-12297 |
| Rhizophoraceae | Rhizophora mangle | 1 | nbisL1-mrna-12819 |
| Salicaceae | Populus euphratica | 1 | populus_peu13845 |
| Solanaceae | Lycium barbarum | 2 | gene-LOC132609321, gene-LOC132643462 |
| Solanaceae | Solanum chilense | 3 | SOLCI004281200, SOLCI006467400, SOLCI006806900 |
| Solanaceae | Solanum pennellii | 5 | gene-LOC107023302, gene-LOC107026725, gene-LOC107026726 ... |
| Tamaricaceae | Reaumuria soongarica | 1 | STRG.14313_chr08_- |
| Tamaricaceae | Tamarix chinensis | 1 | TC12G1851 |
| Zosteraceae | Zostera marina | 2 | Zosma02g23460.v3.1, Zosma03g21940.v3.1 |