HalophFGD

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Basic Information
Locus ID: BH02.135
Species & Taxonomic ID: Echinochloa crus-galli & 90397
Genome Assembly: GWHBDNR00000000
Description: 2-isopropylmalate synthase
Maps and Mapping Data
Chromosome Start End Strand ID
BH02 1435931 1443030 + BH02.135
Protein Data
Protein Properties:
Theoretical pI Molecular Weight Instability Index Aliphatic Index GRAVY
7.00 61,659.14 Da 40.15 85.15 -0.27
Protein Domain:
Category ID Description Start End Evalue/Score InterPro ID
Pfam PF08502 LeuA allosteric (dimerisation) domain 413 557 1.7E-27 IPR013709
Pfam PF00682 HMGL-like 55 208 7.2E-39 IPR000891
Pfam PF00682 HMGL-like 286 338 2.9E-9 IPR000891
SUPERFAMILY SSF110921 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain 440 557 3.79E-10 IPR036230
SUPERFAMILY SSF51569 Aldolase 286 361 2.38E-14 -
SUPERFAMILY SSF51569 Aldolase 51 209 2.38E-34 -
Gene3D G3DSA:3.20.20.70 Aldolase class I 34 232 4.5E-44 IPR013785
Gene3D G3DSA:3.30.160.270 - 437 558 3.6E-17 IPR036230
Gene3D G3DSA:1.10.238.260 - 345 436 1.6E-19 -
Gene3D G3DSA:3.20.20.70 Aldolase class I 283 342 5.3E-12 IPR013785
SMART SM00917 LeuA_dimer_2 412 558 1.9E-16 IPR013709
ProSiteProfiles PS50991 Pyruvate carboxyltransferase domain. 55 332 9.443915 IPR000891
ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 62 78 - IPR002034
MobiDBLite mobidb-lite consensus disorder prediction 224 262 - -
Gene Ontology
Biological Process:
GO:0009098 (L-leucine biosynthetic process) GO:0019752 (carboxylic acid metabolic process)
Molecular Function:
GO:0003824 (catalytic activity) GO:0003852 (2-isopropylmalate synthase activity) GO:0046912 (acyltransferase activity, acyl groups converted into alkyl on transfer)
KEGG Pathway
KO Term:
K01649 (2-isopropylmalate synthase [EC:2.3.3.13])
Pathway:
ko00290 (Valine, leucine and isoleucine biosynthesis) map00290 (Valine, leucine and isoleucine biosynthesis) ko00620 (Pyruvate metabolism) map00620 (Pyruvate metabolism) ko01100 (Metabolic pathways) map01100 (Metabolic pathways) ko01110 (Biosynthesis of secondary metabolites) map01110 (Biosynthesis of secondary metabolites) ko01210 (2-Oxocarboxylic acid metabolism) map01210 (2-Oxocarboxylic acid metabolism) ko01230 (Biosynthesis of amino acids) map01230 (Biosynthesis of amino acids)
Module:
M00432 (Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate)
Reaction:
R01213 (alpha-Isopropylmalate + CoA <=> Acetyl-CoA + 3-Methyl-2-oxobutanoic acid + H2O)
Best hit
Source Best Hit ID Description E-value
TAIR AT1G74040.1 2-isopropylmalate synthase 1. Encodes an active Arabidopsis isopropylmalate synthase IPMS2. Involved in leucine biosynthesis. Do not participate in the chain elongation of glucosinolates. Expressed constitutively throughout the plant. Loss of IPMS2 can be compensated by a second isopropylmalate synthase gene IPMS1 (At1g18500). 7.84E-185
RefSeq XP_025808491.1 2-isopropylmalate synthase A-like [Panicum hallii] 1.53E-262
Swiss-Prot Q9C550 2-isopropylmalate synthase 2, chloroplastic OS=Arabidopsis thaliana OX=3702 GN=IPMS2 PE=1 SV=1 7.54E-184
TrEMBL A0A3L6RDQ5 2-isopropylmalate synthase OS=Panicum miliaceum OX=4540 GN=C2845_PM06G14780 PE=3 SV=1 7.39E-262
Expression
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BioProject Accession TPM Cultivar Tissue Development Stage Sample Name Description
No sample metadata found.
Network
🔍 Protein-Protein Interaction Network
Orthology
Family Species Count Orthologous Genes
Acanthaceae Avicennia marina 3 jg10976, jg10977, jg5907
Aizoaceae Mesembryanthemum crystallinum 2 gene_15767, gene_19447
Amaranthaceae Atriplex hortensis 2 Ah019627, Ah019628
Amaranthaceae Beta vulgaris 2 BVRB_3g058810, BVRB_3g058820
Amaranthaceae Salicornia bigelovii 2 Sbi_jg38490, Sbi_jg6594
Amaranthaceae Salicornia europaea 1 Seu_jg15332
Amaranthaceae Suaeda aralocaspica 2 GOSA_00006427, GOSA_00006428
Amaranthaceae Suaeda glauca 6 Sgl01897, Sgl01898, Sgl07038, Sgl07039, Sgl44504, Sgl49273
Amaranthaceae Chenopodium album 3 gene:ENSEOMG00000011743, gene:ENSEOMG00000030441 ...
gene:ENSEOMG00000042931
Amaranthaceae Chenopodium quinoa 2 CQ.Regalona.r1.3AG0011030, CQ.Regalona.r1.3BG0011260
Anacardiaceae Pistacia vera 1 pistato.v30243490
Apiaceae Apium graveolens 1 Ag5G02859
Arecaceae Cocos nucifera 1 COCNU_12G004560
Arecaceae Phoenix dactylifera 1 gene-LOC103705082
Asparagaceae Asparagus officinalis 4 AsparagusV1_04.1953.V1.1, AsparagusV1_04.1955.V1.1 ...
AsparagusV1_Unassigned.957.V1.1, AsparagusV1_Unassigned.958.V1.1
Asteraceae Flaveria trinervia 2 Ftri11G03059, Ftri12G07723
Brassicaceae Arabidopsis thaliana 4 AT1G18500.1, AT1G74040.1, AT5G23010.1, AT5G23020.1
Brassicaceae Eutrema salsugineum 5 Thhalv10003976m.g.v1.0, Thhalv10004072m.g.v1.0 ...
Thhalv10005522m.g.v1.0, Thhalv10007073m.g.v1.0, Thhalv10018267m.g.v1.0
Brassicaceae Schrenkiella parvula 5 Sp1g16450.v2.2, Sp2g24100.v2.2, Sp2g24110.v2.2 ...
Sp5g29260.v2.2, Sp6g02930.v2.2
Brassicaceae Brassica nigra 8 BniB02g076300.2N, BniB02g076310.2N, BniB03g028050.2N ...
BniB04g003060.2N, BniB04g032970.2N, BniB05g055400.2N, BniB08g036280.2N, BniB08g045890.2N
Casuarinaceae Casuarina equisetifolia 2 Ceq06G2205, Ceq09G0942
Casuarinaceae Casuarina glauca 2 Cgl06G2325, Cgl09G1024
Cymodoceaceae Cymodocea nodosa 1 gene.Cymno05g02310
Dunaliellaceae Dunaliella salina 2 Dusal.0217s00013.v1.0, Dusal.0217s00014.v1.0
Hydrocharitaceae Thalassia testudinum 1 gene.Thate08g08470
Nitrariaceae Nitraria sibirica 4 evm.TU.LG02.2457, evm.TU.LG11.123, evm.TU.LG11.124 ...
evm.TU.LG11.125
Plantaginaceae Plantago ovata 2 Pov_00023467, Pov_00026884
Plumbaginaceae Limonium bicolor 1 Lb7G33591
Poaceae Echinochloa crus-galli 10 AH02.813, AH04.240, AH05.159, BH02.108, BH02.135, BH04.237 ...
BH05.184, CH02.161, CH04.256, CH05.242
Poaceae Eleusine coracana subsp. coracana 4 gene-QOZ80_5AG0380830, gene-QOZ80_5BG0427930 ...
gene-QOZ80_9AG0674100, gene-QOZ80_9BG0697880
Poaceae Hordeum vulgare 1 HORVU.MOREX.r3.5HG0460900.1
Poaceae Lolium multiflorum 3 gene-QYE76_003279, gene-QYE76_003349, gene-QYE76_052410
Poaceae Oryza coarctata 4 Oco21G000770, Oco22G001620, Oco23G001530, Oco24G000960
Poaceae Oryza sativa 2 LOC_Os11g04670.1, LOC_Os12g04440.1
Poaceae Paspalum vaginatum 1 gene-BS78_05G039500
Poaceae Puccinellia tenuiflora 3 Pt_Chr0500049, Pt_Chr0703001, Pt_Chr0703081
Poaceae Sporobolus alterniflorus 2 Chr16G009170, Chr17G008190
Poaceae Thinopyrum elongatum 1 Tel5E01G238500
Poaceae Triticum dicoccoides 3 gene_TRIDC5AG022230, gene_TRIDC5BG023720 ...
gene_TRIDC7AG022330
Poaceae Triticum aestivum 4 TraesCS5A02G131300.1, TraesCS5B02G133500.1 ...
TraesCS5D02G139800.1, TraesCS7A02G179500.1
Poaceae Zea mays 4 Zm00001eb093160_P001, Zm00001eb196510_P001 ...
Zm00001eb278820_P001, Zm00001eb405040_P001
Poaceae Zoysia japonica 2 nbis-gene-27033, nbis-gene-51079
Poaceae Zoysia macrostachya 1 Zma_g18398
Portulacaceae Portulaca oleracea 4 evm.TU.LG04.828, evm.TU.LG05.2106, evm.TU.LG06.1512 ...
evm.TU.LG11.875
Posidoniaceae Posidonia oceanica 1 gene.Posoc01g05010
Rhizophoraceae Bruguiera sexangula 1 evm.TU.Scaffold_3_RagTag.1457
Rhizophoraceae Carallia pectinifolia 1 nbisL1-mrna-1766
Rhizophoraceae Ceriops tagal 1 nbisL1-mrna-1548
Rhizophoraceae Ceriops zippeliana 1 nbisL1-mrna-2684
Rhizophoraceae Kandelia candel 1 evm.TU.utg000019l.366
Rhizophoraceae Kandelia obovata 1 Maker00001810
Rhizophoraceae Rhizophora apiculata 1 nbisL1-mrna-12297
Rhizophoraceae Rhizophora mangle 1 nbisL1-mrna-12819
Salicaceae Populus euphratica 1 populus_peu13845
Solanaceae Lycium barbarum 2 gene-LOC132609321, gene-LOC132643462
Solanaceae Solanum chilense 3 SOLCI004281200, SOLCI006467400, SOLCI006806900
Solanaceae Solanum pennellii 5 gene-LOC107023302, gene-LOC107026725, gene-LOC107026726 ...
gene-LOC107028537, gene-LOC107032143
Tamaricaceae Reaumuria soongarica 1 STRG.14313_chr08_-
Tamaricaceae Tamarix chinensis 1 TC12G1851
Zosteraceae Zostera marina 2 Zosma02g23460.v3.1, Zosma03g21940.v3.1
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