halophFGD

Basic Information

Locus ID: Ag9G00986

Species & Taxonomic ID: Apium graveolens & 4045

Genome Assembly: GCA_009905375.1

Description: belongs to the HisA HisF family

Maps and Mapping Data

Chromosome	Start	End	Strand	ID
chr9	108439692	108445488	-	Ag9G00986

Protein Data

Protein Properties:

Theoretical pI	Molecular Weight	Instability Index	Aliphatic Index	GRAVY
5.58	62,159.00 Da	39.16	87.61	-0.19

Protein Domain:

Category	ID	Description	Start	End	Evalue/Score	InterPro ID
CDD	cd04731	HisF	265	567	3.84693E-105	IPR004651
CDD	cd01748	GATase1_IGP_Synthase	60	247	1.39746E-94	IPR010139
Pfam	PF00977	Histidine biosynthesis protein	264	555	7.0E-45	IPR006062
Pfam	PF00117	Glutamine amidotransferase class-I	62	250	9.2E-21	IPR017926
SUPERFAMILY	SSF51366	Ribulose-phoshate binding barrel	265	572	8.63E-62	IPR011060
SUPERFAMILY	SSF52317	Class I glutamine amidotransferase-like	59	248	8.28E-48	IPR029062
Gene3D	G3DSA:3.40.50.880	-	56	262	7.5E-70	IPR029062
Gene3D	G3DSA:3.20.20.70	Aldolase class I	263	573	6.0E-151	IPR013785
TIGRFAM	TIGR00735	hisF: imidazoleglycerol phosphate synthase, cyclase subunit	263	572	3.2E-89	IPR004651
TIGRFAM	TIGR01855	IMP_synth_hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit	60	247	1.3E-60	IPR010139
PIRSF	PIRSF036936	IGPS_HisHF	248	573	4.1E-177	IPR014640
PIRSF	PIRSF036936	IGPS_HisHF	57	255	7.8E-79	IPR014640
ProSiteProfiles	PS51273	Glutamine amidotransferase type 1 domain profile.	59	275	29.455818	-
Hamap	MF_00278	Imidazole glycerol phosphate synthase subunit HisH [hisH].	59	260	31.875488	IPR010139

Gene Ontology

Biological Process:

GO:0000105 (L-histidine biosynthetic process)

Molecular Function:

GO:0000107 (imidazoleglycerol-phosphate synthase activity) GO:0003824 (catalytic activity) GO:0016763 (pentosyltransferase activity) GO:0016833 (oxo-acid-lyase activity)

KEGG Pathway

KO Term:

K01663 (imidazole glycerol-phosphate synthase [EC:4.3.2.10])

Pathway:

ko00340 (Histidine metabolism) map00340 (Histidine metabolism) ko01100 (Metabolic pathways) map01100 (Metabolic pathways) ko01110 (Biosynthesis of secondary metabolites) map01110 (Biosynthesis of secondary metabolites) ko01230 (Biosynthesis of amino acids) map01230 (Biosynthesis of amino acids)

Module:

M00026 (Histidine biosynthesis, PRPP => histidine)

Reaction:

R04558 (N-(5'-Phospho-D-1'-ribulosylformimino)-5-amino-1-(5''-phospho-D-ribosyl)-4-imidazolecarboxamide + L-Glutamine <=> D-erythro-1-(Imidazol-4-yl)glycerol 3-phosphate + 1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide + L-Glutamate)

Best hit

Source	Best Hit ID	Description
TAIR	AT4G26900.1	HIS HF. encodes a glutamine amidotransferase and cyclase, catalyzes the fifth and sixth steps of the histidine biosynthetic pathway
RefSeq	XP_017214786.1	PREDICTED: imidazole glycerol phosphate synthase hisHF, chloroplastic isoform X1 [Daucus carota subsp. sativus]
Swiss-Prot	Q9SZ30	Imidazole glycerol phosphate synthase hisHF, chloroplastic OS=Arabidopsis thaliana OX=3702 GN=HISN4 PE=2 SV=1
TrEMBL	A0A5B7BXC7	GATase domain-containing protein (Fragment) OS=Davidia involucrata OX=16924 GN=Din_041224 PE=3 SV=1

Expression

BioProject	Accession	TPM	Cultivar	Tissue	Development Stage	Sample Name	Description
PRJNA723697	SRX10692252	43.497814	Shengqin NO.2	seed	S1-1	S1-1	initial formation stage (S1)
PRJNA723697	SRX10692254	23.003313	Shengqin NO.2	seed	S1-3	S1-3	initial formation stage (S1)
PRJNA723697	SRX10692255	20.681202	Shengqin NO.2	seed	S3-1	S3-1	middle development stage (S3)
PRJNA723697	SRX10692256	22.21891	Shengqin NO.2	seed	S3-2	S3-2	middle development stage (S3)
PRJNA723697	SRX10692257	23.87958	Shengqin NO.2	seed	S3-3	S3-3	middle development stage (S3)
PRJNA723697	SRX10692258	26.146957	Shengqin NO.2	seed	S5-1	S5-1	maturation stage (S5)
PRJNA723697	SRX10692259	15.438176	Shengqin NO.2	seed	S5-2	S5-2	maturation stage (S5)
PRJNA723697	SRX10692260	11.594615	Shengqin NO.2	seed	S5-3	S5-3	maturation stage (S5)
PRJNA884666	SRX17729272	41.862938	celery	anther		W99A-r1	male sterile lineÂ
PRJNA884666	SRX17729273	41.925529	celery	anther		W99A-r2	male sterile lineÂ
PRJNA884666	SRX17729274	45.299606	celery	anther		W99A-r3	male sterile lineÂ
PRJNA884666	SRX17729275	49.85638	celery	anther		W99B-r1	maintainer line
PRJNA884666	SRX17729276	44.304192	celery	anther		W99B-r2	maintainer line
PRJNA884666	SRX17729277	35.590866	celery	anther		W99B-r3	maintainer line
PRJNA884180	SRX17743889	16.755144	var. secalinum Yablochny	collenchyma		Col_S1_rep1-1
PRJNA884180	SRX17748056	21.254082	var. secalinum Yablochny	collenchyma		Col_S1_rep3	biological replicate 3
PRJNA884180	SRX17748057	21.196095	var. secalinum Yablochny	collenchyma		Col_S1_rep4	biological replicate 4
PRJNA884180	SRX17748678	29.670631	var. secalinum Yablochny	parenchyma		Par_S1_rep1	Biological replicate 1
PRJNA884180	SRX17748679	27.172821	var. secalinum Yablochny	parenchyma		Par_S1_rep2	Biological replicate 2
PRJNA884180	SRX17748680	29.901987	var. secalinum Yablochny	parenchyma		Par_S1_rep3	Biological replicate 3
PRJNA884180	SRX17748681	37.035049	var. secalinum Yablochny	parenchyma		Par_S1_rep4	Biological replicate 4
PRJNA884180	SRX17748898	35.975605	var. secalinum Yablochny	vascular bundle		Vas_S1_rep1	Biological replicate 1
PRJNA884180	SRX17748899	46.960587	var. secalinum Yablochny	vascular bundle		Vas_S1_rep2	Biological replicate 2
PRJNA884180	SRX17748900	38.855511	var. secalinum Yablochny	vascular bundle		Vas_S1_rep3	Biological replicate 3
PRJNA884180	SRX17748901	42.332642	var. secalinum Yablochny	vascular bundle		Vas_S1_rep4	Biological replicate 4
PRJNA884180	SRX17749129	36.950951	var. secalinum Yablochny	part of the celery petiole without collenchyma strands		Collenchyma-free_S1_rep1	Biological replicate 1
PRJNA884180	SRX17749130	31.813536	var. secalinum Yablochny	part of the celery petiole without collenchyma strands		Collenchyma-free_S1_rep2	Biological replicate 2
PRJNA884180	SRX17749131	37.495422	var. secalinum Yablochny	part of the celery petiole without collenchyma strands		Collenchyma-free_S1_rep3	Biological replicate 3
PRJNA884180	SRX17749132	42.957108	var. secalinum Yablochny	part of the celery petiole without collenchyma strands		Collenchyma-free_S1_rep4	Biological replicate 4
PRJNA1124269	SRX24936411	27.536293		leaf		CK1	replicate=biological replicate1
PRJNA1124269	SRX24936412	39.712658		leaf		CK2	replicate=biological replicate2
PRJNA1124269	SRX24936413	34.128059		leaf		CK3	replicate=biological replicate3
PRJNA1124269	SRX24936414	16.682108		leaf		D1	replicate=biological replicate1
PRJNA1124269	SRX24936415	14.510287		leaf		D2	replicate=biological replicate2
PRJNA1124269	SRX24936416	12.803607		leaf		D3	replicate=biological replicate3
PRJNA1124269	SRX24936417	17.531574		leaf		MD1	replicate=biological replicate1
PRJNA1124269	SRX24936418	13.844205		leaf		MD2	replicate=biological replicate2
PRJNA1124269	SRX24936419	14.175481		leaf		MD3	replicate=biological replicate3
PRJNA387092	SRX2833309	47.495781	shanghaihuangxin	leaf	leaves between 0.5 and 1 cm in breadth, folded;	stage 2
PRJNA387092	SRX2833321	30.906975	shanghaihuangxin	leaf	leaves between 2and 2.5 cm in breadth, nearly unfolded, with clear stem exten-sion	stage 5
PRJNA387092	SRX2833323	19.411934	shanghaihuangxin	leaf	leaves >3 cm, unfolded, with clearstem extension	stage 7
PRJNA543957	SRX5879598	28.396816	Zhangzhou lvqing	stem		Se3	100 ppm Na2SeO4
PRJNA543957	SRX5879599	43.247593	Zhangzhou lvqing	stem		Se2	100 ppm Na2SeO4
PRJNA543957	SRX5879600	117.731987	Zhangzhou lvqing	stem		Mock2	mock
PRJNA543957	SRX5879601	85.727303	Zhangzhou lvqing	stem		Mock1	mock
PRJNA543957	SRX5879602	31.467354	Zhangzhou lvqing	stem		Se1	100 ppm Na2SeO4
PRJNA543957	SRX5879603	72.571495	Zhangzhou lvqing	stem		Mock3	mock
PRJNA609149	SRX7815917	34.146107	Jinnan Shiqin	flower bud	early flower bud	early flower bud
PRJNA609149	SRX7815918	35.224888	Jinnan Shiqin	flower bud	middle flower bud	middle flower bud
PRJNA609149	SRX7815919	35.775127	Jinnan Shiqin	flower bud	early flowering period	early flowering period

Network

🔍 Co-expression Network

🔍 Protein-Protein Interaction Network

Orthology

Family	Species	Count	Orthologous Genes
Acanthaceae	Avicennia marina	2	jg24552, jg38392
Aizoaceae	Mesembryanthemum crystallinum	1	gene_24370
Amaranthaceae	Atriplex hortensis	1	Ah026286
Amaranthaceae	Beta vulgaris	1	BVRB_1g012490
Amaranthaceae	Salicornia bigelovii	2	Sbi_jg39471, Sbi_jg54872
Amaranthaceae	Salicornia europaea	1	Seu_jg14864
Amaranthaceae	Suaeda aralocaspica	1	GOSA_00015853
Amaranthaceae	Suaeda glauca	2	Sgl78437, Sgl80950
Amaranthaceae	Chenopodium album	3	gene:ENSEOMG00000015251, gene:ENSEOMG00000035601 ... gene:ENSEOMG00000049821
Amaranthaceae	Chenopodium quinoa	1	CQ.Regalona.r1.1BG0012110
Anacardiaceae	Pistacia vera	1	pistato.v30156390
Apiaceae	Apium graveolens	1	Ag9G00986
Arecaceae	Cocos nucifera	1	scaffold000755G000040
Arecaceae	Phoenix dactylifera	1	gene-LOC103715056
Asparagaceae	Asparagus officinalis	1	AsparagusV1_08.3634.V1.1
Asteraceae	Flaveria trinervia	1	Ftri16G07487
Brassicaceae	Arabidopsis thaliana	1	AT4G26900.1
Brassicaceae	Eutrema salsugineum	1	Thhalv10024744m.g.v1.0
Brassicaceae	Schrenkiella parvula	1	Sp7g24850.v2.2
Brassicaceae	Brassica nigra	1	BniB05g010480.2N
Casuarinaceae	Casuarina equisetifolia	1	Ceq01G1326
Casuarinaceae	Casuarina glauca	1	Cgl01G1481
Cymodoceaceae	Cymodocea nodosa	1	gene.Cymno13g04060
Dunaliellaceae	Dunaliella salina	1	Dusal.0119s00020.v1.0
Hydrocharitaceae	Thalassia testudinum	1	gene.Thate01g22800
Nitrariaceae	Nitraria sibirica	1	evm.TU.LG05.1901
Plantaginaceae	Plantago ovata	1	Pov_00008791
Plumbaginaceae	Limonium bicolor	2	Lb1G03192, Lb1G03205
Poaceae	Echinochloa crus-galli	3	AH01.4300, BH01.4605, CH01.4916
Poaceae	Eleusine coracana subsp. coracana	1	gene-QOZ80_3BG0286470
Poaceae	Hordeum vulgare	1	HORVU.MOREX.r3.4HG0390930.1
Poaceae	Lolium multiflorum	3	gene-QYE76_068160, gene-QYE76_069177, gene-QYE76_069243
Poaceae	Oryza coarctata	1	Oco06G008880
Poaceae	Oryza sativa	1	LOC_Os03g15120.1
Poaceae	Paspalum vaginatum	1	gene-BS78_01G412800
Poaceae	Puccinellia tenuiflora	1	Pt_Chr0102110
Poaceae	Sporobolus alterniflorus	2	Chr04G006960, Chr07G004690
Poaceae	Thinopyrum elongatum	1	Tel4E01G383100
Poaceae	Triticum dicoccoides	2	gene_TRIDC4AG011480, gene_TRIDC4BG038870
Poaceae	Triticum aestivum	3	TraesCS4A02G084400.1, TraesCS4B02G219800.1 ... TraesCS4D02G220200.2
Poaceae	Zea mays	1	Zm00001eb011150_P004
Poaceae	Zoysia japonica	1	nbis-gene-2196
Poaceae	Zoysia macrostachya	1	Zma_g1605
Portulacaceae	Portulaca oleracea	2	evm.TU.LG04.1249, evm.TU.LG05.1785
Posidoniaceae	Posidonia oceanica	1	gene.Posoc10g07150
Rhizophoraceae	Bruguiera sexangula	1	evm.TU.Scaffold_7_RagTag.159
Rhizophoraceae	Carallia pectinifolia	1	nbisL1-mrna-19565
Rhizophoraceae	Ceriops tagal	1	nbisL1-mrna-3960
Rhizophoraceae	Ceriops zippeliana	1	nbisL1-mrna-22266
Rhizophoraceae	Kandelia candel	1	evm.TU.utg000028l.96
Rhizophoraceae	Kandelia obovata	1	Maker00010450
Rhizophoraceae	Rhizophora apiculata	1	nbisL1-mrna-8060
Rhizophoraceae	Rhizophora mangle	1	nbisL1-mrna-9721
Salicaceae	Populus euphratica	2	populus_peu01857, populus_peu35958
Solanaceae	Lycium barbarum	1	gene-LOC132617353
Solanaceae	Solanum chilense	1	SOLCI002512000
Solanaceae	Solanum pennellii	1	gene-LOC107026296
Tamaricaceae	Reaumuria soongarica	1	gene_2213
Tamaricaceae	Tamarix chinensis	1	TC03G1627
Zosteraceae	Zostera marina	1	Zosma06g19430.v3.1