Basic Information
Locus ID:
Ag4G00731
Species & Taxonomic ID:
Apium graveolens & 4045
Genome Assembly:
GCA_009905375.1
Description:
Belongs to the short-chain dehydrogenases reductases (SDR) family
Maps and Mapping Data
| Chromosome | Start | End | Strand | ID |
|---|---|---|---|---|
| chr4 | 65793793 | 65795359 | + | Ag4G00731 |
Protein Data
Protein Properties:
| Theoretical pI | Molecular Weight | Instability Index | Aliphatic Index | GRAVY |
|---|---|---|---|---|
| 9.60 | 36,024.86 Da | 26.41 | 105.62 | 0.15 |
Protein Domain:
| Category | ID | Description | Start | End | Evalue/Score | InterPro ID |
|---|---|---|---|---|---|---|
| CDD | cd05356 | 17beta-HSD1_like_SDR_c | 56 | 299 | 5.05137E-111 | - |
| Pfam | PF00106 | short chain dehydrogenase | 58 | 251 | 2.0E-38 | IPR002347 |
| SUPERFAMILY | SSF51735 | NAD(P)-binding Rossmann-fold domains | 56 | 318 | 5.16E-46 | IPR036291 |
| Gene3D | G3DSA:3.40.50.720 | - | 52 | 277 | 4.8E-46 | - |
| PIRSF | PIRSF000126 | 11-beta-HSD1 | 10 | 318 | 3.0E-93 | - |
| PRINTS | PR00081 | Glucose/ribitol dehydrogenase family signature | 183 | 199 | 4.3E-18 | IPR002347 |
| PRINTS | PR00081 | Glucose/ribitol dehydrogenase family signature | 58 | 75 | 4.3E-18 | IPR002347 |
| PRINTS | PR00081 | Glucose/ribitol dehydrogenase family signature | 233 | 250 | 4.3E-18 | IPR002347 |
| PRINTS | PR00081 | Glucose/ribitol dehydrogenase family signature | 212 | 231 | 4.3E-18 | IPR002347 |
| PRINTS | PR00081 | Glucose/ribitol dehydrogenase family signature | 134 | 145 | 4.3E-18 | IPR002347 |
| PRINTS | PR00080 | Short-chain dehydrogenase/reductase (SDR) superfamily signature | 134 | 145 | 4.1E-6 | IPR002347 |
| PRINTS | PR00080 | Short-chain dehydrogenase/reductase (SDR) superfamily signature | 212 | 231 | 4.1E-6 | IPR002347 |
| PRINTS | PR00080 | Short-chain dehydrogenase/reductase (SDR) superfamily signature | 189 | 197 | 4.1E-6 | IPR002347 |
Gene Ontology
Molecular Function:
KEGG Pathway
Pathway:
ko00062 (Fatty acid elongation)
map00062 (Fatty acid elongation)
ko00140 (Steroid hormone biosynthesis)
map00140 (Steroid hormone biosynthesis)
ko01040 (Biosynthesis of unsaturated fatty acids)
map01040 (Biosynthesis of unsaturated fatty acids)
ko01100 (Metabolic pathways)
map01100 (Metabolic pathways)
ko01110 (Biosynthesis of secondary metabolites)
map01110 (Biosynthesis of secondary metabolites)
ko01212 (Fatty acid metabolism)
map01212 (Fatty acid metabolism)
Reaction:
R02352 (Estradiol-17beta + NAD+ <=> Estrone + NADH + H+)
R02353 (Estradiol-17beta + NADP+ <=> Estrone + NADPH + H+)
R04681 (Estriol + NAD+ <=> 16alpha-Hydroxyestrone + NADH + H+)
R04682 (Estriol + NADP+ <=> 16alpha-Hydroxyestrone + NADPH + H+)
R07759 (3-Oxostearoyl-CoA + NADPH + H+ <=> 3-Hydroxyoctadecanoyl-CoA + NADP+)
R08945 (11beta,17beta-Dihydroxy-4-androsten-3-one + NAD+ <=> 11beta-Hydroxyandrost-4-ene-3,17-dione + NADH + H+)
R08980 (11beta,17beta-Dihydroxy-4-androsten-3-one + NADP+ <=> 11beta-Hydroxyandrost-4-ene-3,17-dione + NADPH + H+)
R10826 (Very-long-chain (3R)-3-hydroxyacyl-CoA + NADP+ <=> Very-long-chain 3-oxoacyl-CoA + NADPH + H+)
Best hit
| Source | Best Hit ID | Description | E-value |
|---|---|---|---|
| TAIR | AT1G67730.1 | beta-ketoacyl reductase 1. Encodes one of the two Arabidopsis homologues to YBR159w encoding a S. cerevisiae beta-ketoacyl reductase (KCR), which catalyzes the first reduction during VLCFA (very long chain fatty acids, >18 carbon) elongation: KCR1 (At1g67730), KCR2 (At1g24470). Complementation of the yeast ybr159Delta mutant demonstrated that the two KCR proteins are divergent and that only AtKCR1 can restore heterologous elongase activity similar to the native yeast KCR gene. | 0 |
| RefSeq | XP_017242570.1 | PREDICTED: very-long-chain 3-oxoacyl-CoA reductase 1-like [Daucus carota subsp. sativus] | 0 |
| Q8L9C4 | Very-long-chain 3-oxoacyl-CoA reductase 1 OS=Arabidopsis thaliana OX=3702 GN=KCR1 PE=1 SV=1 | 0 | |
| TrEMBL | A0A161Y095 | Very-long-chain 3-oxoacyl-CoA reductase 1-like OS=Daucus carota subsp. sativus OX=79200 GN=DCAR_011281 PE=4 SV=1 | 0 |
Expression
| BioProject | Accession | TPM | Cultivar | Tissue | Development Stage | Sample Name | Description |
|---|---|---|---|---|---|---|---|
| PRJNA723697 | SRX10692252 | 0.461086 | Shengqin NO.2 | seed | S1-1 | S1-1 | initial formation stage (S1) |
| PRJNA723697 | SRX10692254 | 0 | Shengqin NO.2 | seed | S1-3 | S1-3 | initial formation stage (S1) |
| PRJNA723697 | SRX10692255 | 0 | Shengqin NO.2 | seed | S3-1 | S3-1 | middle development stage (S3) |
| PRJNA723697 | SRX10692256 | 0 | Shengqin NO.2 | seed | S3-2 | S3-2 | middle development stage (S3) |
| PRJNA723697 | SRX10692257 | 0 | Shengqin NO.2 | seed | S3-3 | S3-3 | middle development stage (S3) |
| PRJNA723697 | SRX10692258 | 0 | Shengqin NO.2 | seed | S5-1 | S5-1 | maturation stage (S5) |
| PRJNA723697 | SRX10692259 | 0.099854 | Shengqin NO.2 | seed | S5-2 | S5-2 | maturation stage (S5) |
| PRJNA723697 | SRX10692260 | 0 | Shengqin NO.2 | seed | S5-3 | S5-3 | maturation stage (S5) |
| PRJNA884666 | SRX17729272 | 52.401539 | celery | anther | W99A-r1 | male sterile line | |
| PRJNA884666 | SRX17729273 | 44.876541 | celery | anther | W99A-r2 | male sterile line | |
| PRJNA884666 | SRX17729274 | 47.488739 | celery | anther | W99A-r3 | male sterile line | |
| PRJNA884666 | SRX17729275 | 30.689102 | celery | anther | W99B-r1 | maintainer line | |
| PRJNA884666 | SRX17729276 | 48.296814 | celery | anther | W99B-r2 | maintainer line | |
| PRJNA884666 | SRX17729277 | 56.563301 | celery | anther | W99B-r3 | maintainer line | |
| PRJNA884180 | SRX17743889 | 0.106537 | var. secalinum Yablochny | collenchyma | Col_S1_rep1-1 | ||
| PRJNA884180 | SRX17748056 | 1.073903 | var. secalinum Yablochny | collenchyma | Col_S1_rep3 | biological replicate 3 | |
| PRJNA884180 | SRX17748057 | 0.050388 | var. secalinum Yablochny | collenchyma | Col_S1_rep4 | biological replicate 4 | |
| PRJNA884180 | SRX17748678 | 0 | var. secalinum Yablochny | parenchyma | Par_S1_rep1 | Biological replicate 1 | |
| PRJNA884180 | SRX17748679 | 0.248202 | var. secalinum Yablochny | parenchyma | Par_S1_rep2 | Biological replicate 2 | |
| PRJNA884180 | SRX17748680 | 0 | var. secalinum Yablochny | parenchyma | Par_S1_rep3 | Biological replicate 3 | |
| PRJNA884180 | SRX17748681 | 0 | var. secalinum Yablochny | parenchyma | Par_S1_rep4 | Biological replicate 4 | |
| PRJNA884180 | SRX17748898 | 0 | var. secalinum Yablochny | vascular bundle | Vas_S1_rep1 | Biological replicate 1 | |
| PRJNA884180 | SRX17748899 | 0 | var. secalinum Yablochny | vascular bundle | Vas_S1_rep2 | Biological replicate 2 | |
| PRJNA884180 | SRX17748900 | 0 | var. secalinum Yablochny | vascular bundle | Vas_S1_rep3 | Biological replicate 3 | |
| PRJNA884180 | SRX17748901 | 0 | var. secalinum Yablochny | vascular bundle | Vas_S1_rep4 | Biological replicate 4 | |
| PRJNA884180 | SRX17749129 | 0.187018 | var. secalinum Yablochny | part of the celery petiole without collenchyma strands | Collenchyma-free_S1_rep1 | Biological replicate 1 | |
| PRJNA884180 | SRX17749130 | 0.618301 | var. secalinum Yablochny | part of the celery petiole without collenchyma strands | Collenchyma-free_S1_rep2 | Biological replicate 2 | |
| PRJNA884180 | SRX17749131 | 0 | var. secalinum Yablochny | part of the celery petiole without collenchyma strands | Collenchyma-free_S1_rep3 | Biological replicate 3 | |
| PRJNA884180 | SRX17749132 | 0 | var. secalinum Yablochny | part of the celery petiole without collenchyma strands | Collenchyma-free_S1_rep4 | Biological replicate 4 | |
| PRJNA1124269 | SRX24936411 | 0.280791 | leaf | CK1 | replicate=biological replicate1 | ||
| PRJNA1124269 | SRX24936412 | 0.150136 | leaf | CK2 | replicate=biological replicate2 | ||
| PRJNA1124269 | SRX24936413 | 0.232692 | leaf | CK3 | replicate=biological replicate3 | ||
| PRJNA1124269 | SRX24936414 | 0 | leaf | D1 | replicate=biological replicate1 | ||
| PRJNA1124269 | SRX24936415 | 2.998041 | leaf | D2 | replicate=biological replicate2 | ||
| PRJNA1124269 | SRX24936416 | 0 | leaf | D3 | replicate=biological replicate3 | ||
| PRJNA1124269 | SRX24936417 | 0 | leaf | MD1 | replicate=biological replicate1 | ||
| PRJNA1124269 | SRX24936418 | 0 | leaf | MD2 | replicate=biological replicate2 | ||
| PRJNA1124269 | SRX24936419 | 0 | leaf | MD3 | replicate=biological replicate3 | ||
| PRJNA387092 | SRX2833309 | 0.4749 | shanghaihuangxin | leaf | leaves between 0.5 and 1 cm in breadth, folded; | stage 2 | |
| PRJNA387092 | SRX2833321 | 0 | shanghaihuangxin | leaf | leaves between 2and 2.5 cm in breadth, nearly unfolded, with clear stem exten-sion | stage 5 | |
| PRJNA387092 | SRX2833323 | 0 | shanghaihuangxin | leaf | leaves >3 cm, unfolded, with clearstem extension | stage 7 | |
| PRJNA543957 | SRX5879598 | 0 | Zhangzhou lvqing | stem | Se3 | 100 ppm Na2SeO4 | |
| PRJNA543957 | SRX5879599 | 0 | Zhangzhou lvqing | stem | Se2 | 100 ppm Na2SeO4 | |
| PRJNA543957 | SRX5879600 | 0 | Zhangzhou lvqing | stem | Mock2 | mock | |
| PRJNA543957 | SRX5879601 | 0 | Zhangzhou lvqing | stem | Mock1 | mock | |
| PRJNA543957 | SRX5879602 | 0 | Zhangzhou lvqing | stem | Se1 | 100 ppm Na2SeO4 | |
| PRJNA543957 | SRX5879603 | 0 | Zhangzhou lvqing | stem | Mock3 | mock | |
| PRJNA609149 | SRX7815917 | 9.555244 | Jinnan Shiqin | flower bud | early flower bud | early flower bud | |
| PRJNA609149 | SRX7815918 | 13.751136 | Jinnan Shiqin | flower bud | middle flower bud | middle flower bud | |
| PRJNA609149 | SRX7815919 | 14.491191 | Jinnan Shiqin | flower bud | early flowering period | early flowering period |
Orthology