halophFGD

Basic Information

Locus ID: Ag2G00476

Species & Taxonomic ID: Apium graveolens & 4045

Genome Assembly: GCA_009905375.1

Description: biotin synthase

Maps and Mapping Data

Chromosome	Start	End	Strand	ID
chr2	11775981	11788359	+	Ag2G00476

Protein Data

Protein Properties:

Theoretical pI	Molecular Weight	Instability Index	Aliphatic Index	GRAVY
6.64	62,644.06 Da	40.00	84.19	-0.25

Protein Domain:

Category	ID	Description	Start	End	Evalue/Score	InterPro ID
CDD	cd01335	Radical_SAM	99	299	1.11141E-18	-
Pfam	PF06968	Biotin and Thiamin Synthesis associated domain	271	356	7.0E-15	IPR010722
Pfam	PF04055	Radical SAM superfamily	98	257	9.7E-14	IPR007197
SUPERFAMILY	SSF102114	Radical SAM enzymes	54	356	5.89E-83	-
SUPERFAMILY	SSF53254	Phosphoglycerate mutase-like	373	548	1.16E-17	IPR029033
Gene3D	G3DSA:3.40.50.1240	-	361	557	1.6E-13	IPR029033
Gene3D	G3DSA:3.20.20.70	Aldolase class I	53	360	2.3E-133	IPR013785
SMART	SM00876	BATS_2	271	363	3.1E-33	IPR010722
SMART	SM00729	MiaB	92	300	2.1E-42	IPR006638
TIGRFAM	TIGR00433	bioB: biotin synthase	63	356	7.0E-113	IPR002684
ProSiteProfiles	PS51918	Radical SAM core domain profile.	87	316	33.283882	IPR007197
Hamap	MF_01694	Biotin synthase [bioB].	54	364	39.674995	IPR002684
SFLD	SFLDS00029	Radical SAM	49	363	0.0	IPR007197
SFLD	SFLDF00272	biotin synthase	49	363	0.0	IPR024177

Gene Ontology

Biological Process:

GO:0009102 (biotin biosynthetic process)

Molecular Function:

GO:0003824 (catalytic activity) GO:0004076 (biotin synthase activity) GO:0051536 (iron-sulfur cluster binding)

KEGG Pathway

KO Term:

K01012 (biotin synthase [EC:2.8.1.6])

Pathway:

ko00780 (Biotin metabolism) map00780 (Biotin metabolism) ko01100 (Metabolic pathways) map01100 (Metabolic pathways)

Module:

M00123 (Biotin biosynthesis, pimeloyl-ACP/CoA => biotin) M00573 (Biotin biosynthesis, BioI pathway, long-chain-acyl-ACP => pimeloyl-ACP => biotin) M00577 (Biotin biosynthesis, BioW pathway, pimelate => pimeloyl-CoA => biotin)

Reaction:

R01078 (Dethiobiotin + Sulfur donor + 2 S-Adenosyl-L-methionine + 2 e- + 2 H+ <=> Biotin + 2 L-Methionine + 2 5'-Deoxyadenosine)

Best hit

Source	Best Hit ID	Description
TAIR	AT2G43360.1	Radical SAM superfamily protein. Catalyzes the conversion of dethiobiotin to biotin.
RefSeq	XP_017226619.1	PREDICTED: biotin synthase [Daucus carota subsp. sativus]
Swiss-Prot	P54967	Biotin synthase, mitochondrial OS=Arabidopsis thaliana OX=3702 GN=BIO2 PE=1 SV=1
TrEMBL	A0A2U1MPY1	biotin synthase OS=Artemisia annua OX=35608 GN=CTI12_AA325490 PE=3 SV=1

Expression

BioProject	Accession	TPM	Cultivar	Tissue	Development Stage	Sample Name	Description
PRJNA723697	SRX10692252	56.583855	Shengqin NO.2	seed	S1-1	S1-1	initial formation stage (S1)
PRJNA723697	SRX10692254	50.261616	Shengqin NO.2	seed	S1-3	S1-3	initial formation stage (S1)
PRJNA723697	SRX10692255	48.316948	Shengqin NO.2	seed	S3-1	S3-1	middle development stage (S3)
PRJNA723697	SRX10692256	39.785088	Shengqin NO.2	seed	S3-2	S3-2	middle development stage (S3)
PRJNA723697	SRX10692257	38.645676	Shengqin NO.2	seed	S3-3	S3-3	middle development stage (S3)
PRJNA723697	SRX10692258	29.095879	Shengqin NO.2	seed	S5-1	S5-1	maturation stage (S5)
PRJNA723697	SRX10692259	43.24173	Shengqin NO.2	seed	S5-2	S5-2	maturation stage (S5)
PRJNA723697	SRX10692260	33.36573	Shengqin NO.2	seed	S5-3	S5-3	maturation stage (S5)
PRJNA884666	SRX17729272	95.918449	celery	anther		W99A-r1	male sterile lineÂ
PRJNA884666	SRX17729273	95.060509	celery	anther		W99A-r2	male sterile lineÂ
PRJNA884666	SRX17729274	90.885529	celery	anther		W99A-r3	male sterile lineÂ
PRJNA884666	SRX17729275	96.736038	celery	anther		W99B-r1	maintainer line
PRJNA884666	SRX17729276	88.66349	celery	anther		W99B-r2	maintainer line
PRJNA884666	SRX17729277	97.445015	celery	anther		W99B-r3	maintainer line
PRJNA884180	SRX17743889	33.633781	var. secalinum Yablochny	collenchyma		Col_S1_rep1-1
PRJNA884180	SRX17748056	46.297237	var. secalinum Yablochny	collenchyma		Col_S1_rep3	biological replicate 3
PRJNA884180	SRX17748057	28.143608	var. secalinum Yablochny	collenchyma		Col_S1_rep4	biological replicate 4
PRJNA884180	SRX17748678	44.328087	var. secalinum Yablochny	parenchyma		Par_S1_rep1	Biological replicate 1
PRJNA884180	SRX17748679	42.450821	var. secalinum Yablochny	parenchyma		Par_S1_rep2	Biological replicate 2
PRJNA884180	SRX17748680	63.542522	var. secalinum Yablochny	parenchyma		Par_S1_rep3	Biological replicate 3
PRJNA884180	SRX17748681	56.061329	var. secalinum Yablochny	parenchyma		Par_S1_rep4	Biological replicate 4
PRJNA884180	SRX17748898	39.289497	var. secalinum Yablochny	vascular bundle		Vas_S1_rep1	Biological replicate 1
PRJNA884180	SRX17748899	38.708229	var. secalinum Yablochny	vascular bundle		Vas_S1_rep2	Biological replicate 2
PRJNA884180	SRX17748900	36.308037	var. secalinum Yablochny	vascular bundle		Vas_S1_rep3	Biological replicate 3
PRJNA884180	SRX17748901	34.230377	var. secalinum Yablochny	vascular bundle		Vas_S1_rep4	Biological replicate 4
PRJNA884180	SRX17749129	42.340771	var. secalinum Yablochny	part of the celery petiole without collenchyma strands		Collenchyma-free_S1_rep1	Biological replicate 1
PRJNA884180	SRX17749130	39.524792	var. secalinum Yablochny	part of the celery petiole without collenchyma strands		Collenchyma-free_S1_rep2	Biological replicate 2
PRJNA884180	SRX17749131	44.710697	var. secalinum Yablochny	part of the celery petiole without collenchyma strands		Collenchyma-free_S1_rep3	Biological replicate 3
PRJNA884180	SRX17749132	42.107136	var. secalinum Yablochny	part of the celery petiole without collenchyma strands		Collenchyma-free_S1_rep4	Biological replicate 4
PRJNA1124269	SRX24936411	21.858746		leaf		CK1	replicate=biological replicate1
PRJNA1124269	SRX24936412	23.617674		leaf		CK2	replicate=biological replicate2
PRJNA1124269	SRX24936413	20.203726		leaf		CK3	replicate=biological replicate3
PRJNA1124269	SRX24936414	46.901562		leaf		D1	replicate=biological replicate1
PRJNA1124269	SRX24936415	45.018551		leaf		D2	replicate=biological replicate2
PRJNA1124269	SRX24936416	47.464478		leaf		D3	replicate=biological replicate3
PRJNA1124269	SRX24936417	33.355183		leaf		MD1	replicate=biological replicate1
PRJNA1124269	SRX24936418	18.645773		leaf		MD2	replicate=biological replicate2
PRJNA1124269	SRX24936419	24.012293		leaf		MD3	replicate=biological replicate3
PRJNA387092	SRX2833309	52.890774	shanghaihuangxin	leaf	leaves between 0.5 and 1 cm in breadth, folded;	stage 2
PRJNA387092	SRX2833321	50.676228	shanghaihuangxin	leaf	leaves between 2and 2.5 cm in breadth, nearly unfolded, with clear stem exten-sion	stage 5
PRJNA387092	SRX2833323	72.16346	shanghaihuangxin	leaf	leaves >3 cm, unfolded, with clearstem extension	stage 7
PRJNA543957	SRX5879598	110.164322	Zhangzhou lvqing	stem		Se3	100 ppm Na2SeO4
PRJNA543957	SRX5879599	58.489872	Zhangzhou lvqing	stem		Se2	100 ppm Na2SeO4
PRJNA543957	SRX5879600	14.248405	Zhangzhou lvqing	stem		Mock2	mock
PRJNA543957	SRX5879601	15.297385	Zhangzhou lvqing	stem		Mock1	mock
PRJNA543957	SRX5879602	117.430489	Zhangzhou lvqing	stem		Se1	100 ppm Na2SeO4
PRJNA543957	SRX5879603	18.016323	Zhangzhou lvqing	stem		Mock3	mock
PRJNA609149	SRX7815917	67.936111	Jinnan Shiqin	flower bud	early flower bud	early flower bud
PRJNA609149	SRX7815918	58.239685	Jinnan Shiqin	flower bud	middle flower bud	middle flower bud
PRJNA609149	SRX7815919	49.726044	Jinnan Shiqin	flower bud	early flowering period	early flowering period

Network

🔍 Co-expression Network

🔍 Protein-Protein Interaction Network

Orthology

Family	Species	Count	Orthologous Genes
Acanthaceae	Avicennia marina	2	jg18934, jg5961
Aizoaceae	Mesembryanthemum crystallinum	1	gene_2908
Amaranthaceae	Atriplex hortensis	1	Ah019325
Amaranthaceae	Beta vulgaris	1	BVRB_3g054800
Amaranthaceae	Salicornia bigelovii	2	Sbi_jg15257, Sbi_jg56066
Amaranthaceae	Salicornia europaea	1	Seu_jg26551
Amaranthaceae	Suaeda aralocaspica	1	GOSA_00006281
Amaranthaceae	Suaeda glauca	3	Sgl01702, Sgl01703, Sgl06858
Amaranthaceae	Chenopodium album	3	gene:ENSEOMG00000009410, gene:ENSEOMG00000031343 ... gene:ENSEOMG00000040647
Amaranthaceae	Chenopodium quinoa	2	CQ.Regalona.r1.3AG0000040, CQ.Regalona.r1.4BG0015520
Anacardiaceae	Pistacia vera	1	pistato.v30243650
Apiaceae	Apium graveolens	1	Ag2G00476
Arecaceae	Cocos nucifera	1	scaffold034468G000020
Arecaceae	Phoenix dactylifera	2	gene-LOC103717547, gene-LOC108511610
Asparagaceae	Asparagus officinalis	1	AsparagusV1_10.1343.V1.1
Asteraceae	Flaveria trinervia	1	Ftri17G19843
Brassicaceae	Arabidopsis thaliana	1	AT2G43360.1
Brassicaceae	Eutrema salsugineum	1	Thhalv10001495m.g.v1.0
Brassicaceae	Schrenkiella parvula	1	Sp4g25460.v2.2
Brassicaceae	Brassica nigra	2	BniB06g002130.2N, BniB08g028310.2N
Casuarinaceae	Casuarina equisetifolia	1	Ceq09G2085
Casuarinaceae	Casuarina glauca	1	Cgl09G2284
Cymodoceaceae	Cymodocea nodosa	1	gene.Cymno08g03480
Dunaliellaceae	Dunaliella salina	2	Dusal.0329s00001.v1.0, Dusal.0329s00002.v1.0
Hydrocharitaceae	Thalassia testudinum	1	gene.Thate03g21600
Nitrariaceae	Nitraria sibirica	1	evm.TU.LG11.138
Plantaginaceae	Plantago ovata	1	Pov_00008369
Plumbaginaceae	Limonium bicolor	1	Lb3G20461
Poaceae	Echinochloa crus-galli	3	AH08.2240, BH08.2370, CH08.2546
Poaceae	Eleusine coracana subsp. coracana	2	gene-QOZ80_8AG0638210, gene-QOZ80_8BG0667710
Poaceae	Hordeum vulgare	1	HORVU.MOREX.r3.7HG0686000.1
Poaceae	Lolium multiflorum	1	gene-QYE76_030413
Poaceae	Oryza coarctata	2	Oco15G013680, Oco16G012860
Poaceae	Oryza sativa	1	LOC_Os08g42730.1
Poaceae	Paspalum vaginatum	1	gene-BS78_07G210200
Poaceae	Puccinellia tenuiflora	1	Pt_Chr0403532
Poaceae	Sporobolus alterniflorus	3	Chr16G018390, Chr20G002400, Chr29G001080
Poaceae	Thinopyrum elongatum	1	Tel7E01G466000
Poaceae	Triticum dicoccoides	2	gene_TRIDC7AG035000, gene_TRIDC7BG025990
Poaceae	Triticum aestivum	3	TraesCS7A02G267300.1, TraesCS7B02G164700.1 ... TraesCS7D02G267400.1
Poaceae	Zea mays	2	Zm00001eb037230_P001, Zm00001eb198320_P001
Poaceae	Zoysia japonica	2	nbis-gene-17563, nbis-gene-42757
Poaceae	Zoysia macrostachya	2	Zma_g23355, Zma_g24462
Portulacaceae	Portulaca oleracea	2	evm.TU.LG11.1283, evm.TU.LG11.1286
Posidoniaceae	Posidonia oceanica	1	gene.Posoc05g15540
Rhizophoraceae	Bruguiera sexangula	3	evm.TU.48677.4, evm.TU.Scaffold_3_RagTag.1465 ... evm.TU.Scaffold_7_RagTag.702
Rhizophoraceae	Carallia pectinifolia	1	nbisL1-mrna-1780
Rhizophoraceae	Ceriops tagal	2	nbisL1-mrna-15532, nbisL1-mrna-2155
Rhizophoraceae	Ceriops zippeliana	4	nbisL1-mrna-2693, nbisL1-mrna-2696, nbisL1-mrna-2720 ... nbisL1-mrna-7728
Rhizophoraceae	Kandelia candel	1	evm.TU.utg000019l.358
Rhizophoraceae	Kandelia obovata	1	Maker00002258
Rhizophoraceae	Rhizophora apiculata	3	nbisL1-mrna-12302, nbisL1-mrna-15781, nbisL1-mrna-21674
Rhizophoraceae	Rhizophora mangle	2	nbisL1-mrna-12832, nbisL1-mrna-12852
Salicaceae	Populus euphratica	3	populus_peu22623, populus_peu22631, populus_peu24054
Solanaceae	Lycium barbarum	1	gene-LOC132603380
Solanaceae	Solanum chilense	1	SOLCI004575100
Solanaceae	Solanum pennellii	1	gene-LOC107023660
Tamaricaceae	Reaumuria soongarica	3	gene_10556, gene_12979, gene_2073
Tamaricaceae	Tamarix chinensis	1	TC05G2304
Zosteraceae	Zostera marina	1	Zosma02g07210.v3.1