Basic Information
Locus ID:
Ag10G01498
Species & Taxonomic ID:
Apium graveolens & 4045
Genome Assembly:
GCA_009905375.1
Short Name:
MKK6
Description:
Belongs to the protein kinase superfamily
Maps and Mapping Data
| Chromosome | Start | End | Strand | ID |
|---|---|---|---|---|
| chr10 | 185119697 | 185124085 | + | Ag10G01498 |
Protein Data
Protein Properties:
| Theoretical pI | Molecular Weight | Instability Index | Aliphatic Index | GRAVY |
|---|---|---|---|---|
| 5.75 | 39,439.01 Da | 52.22 | 98.78 | -0.05 |
Protein Domain:
| Category | ID | Description | Start | End | Evalue/Score | InterPro ID |
|---|---|---|---|---|---|---|
| CDD | cd06623 | PKc_MAPKK_plant_like | 82 | 331 | 4.38598E-140 | - |
| Pfam | PF00069 | Protein kinase domain | 68 | 327 | 1.8E-65 | IPR000719 |
| SUPERFAMILY | SSF56112 | Protein kinase-like (PK-like) | 64 | 340 | 5.53E-80 | IPR011009 |
| Gene3D | G3DSA:1.10.510.10 | Transferase(Phosphotransferase) domain 1 | 148 | 344 | 1.5E-58 | - |
| Gene3D | G3DSA:3.30.200.20 | Phosphorylase Kinase; domain 1 | 40 | 146 | 1.4E-28 | - |
| SMART | SM00220 | serkin_6 | 67 | 327 | 1.3E-82 | IPR000719 |
| ProSiteProfiles | PS50011 | Protein kinase domain profile. | 67 | 327 | 45.474037 | IPR000719 |
| ProSitePatterns | PS00107 | Protein kinases ATP-binding region signature. | 73 | 96 | - | IPR017441 |
| ProSitePatterns | PS00108 | Serine/Threonine protein kinases active-site signature. | 185 | 197 | - | IPR008271 |
Gene Ontology
Biological Process:
Molecular Function:
KEGG Pathway
Pathway:
ko01521 (EGFR tyrosine kinase inhibitor resistance)
map01521 (EGFR tyrosine kinase inhibitor resistance)
ko01522 (Endocrine resistance)
map01522 (Endocrine resistance)
ko04010 (MAPK signaling pathway)
map04010 (MAPK signaling pathway)
ko04012 (ErbB signaling pathway)
map04012 (ErbB signaling pathway)
ko04013 (MAPK signaling pathway - fly)
map04013 (MAPK signaling pathway - fly)
ko04014 (Ras signaling pathway)
map04014 (Ras signaling pathway)
ko04015 (Rap1 signaling pathway)
map04015 (Rap1 signaling pathway)
ko04022 (cGMP-PKG signaling pathway)
map04022 (cGMP-PKG signaling pathway)
ko04024 (cAMP signaling pathway)
map04024 (cAMP signaling pathway)
ko04062 (Chemokine signaling pathway)
map04062 (Chemokine signaling pathway)
ko04066 (HIF-1 signaling pathway)
map04066 (HIF-1 signaling pathway)
ko04068 (FoxO signaling pathway)
map04068 (FoxO signaling pathway)
ko04071 (Sphingolipid signaling pathway)
map04071 (Sphingolipid signaling pathway)
ko04072 (Phospholipase D signaling pathway)
map04072 (Phospholipase D signaling pathway)
ko04114 (Oocyte meiosis)
map04114 (Oocyte meiosis)
ko04140 (Autophagy - animal)
map04140 (Autophagy - animal)
ko04150 (mTOR signaling pathway)
map04150 (mTOR signaling pathway)
ko04151 (PI3K-Akt signaling pathway)
map04151 (PI3K-Akt signaling pathway)
map04210 (Apoptosis)
ko04218 (Cellular senescence)
map04218 (Cellular senescence)
ko04320 (Dorso-ventral axis formation)
map04320 (Dorso-ventral axis formation)
ko04370 (VEGF signaling pathway)
map04370 (VEGF signaling pathway)
ko04371 (Apelin signaling pathway)
map04371 (Apelin signaling pathway)
ko04550 (Signaling pathways regulating pluripotency of stem cells)
map04550 (Signaling pathways regulating pluripotency of stem cells)
map04620 (Toll-like receptor signaling pathway)
ko04626 (Plant-pathogen interaction)
map04626 (Plant-pathogen interaction)
map04650 (Natural killer cell mediated cytotoxicity)
map04660 (T cell receptor signaling pathway)
map04662 (B cell receptor signaling pathway)
map04664 (Fc epsilon RI signaling pathway)
map04666 (Fc gamma R-mediated phagocytosis)
map04668 (TNF signaling pathway)
ko04916 (Melanogenesis)
map04916 (Melanogenesis)
Best hit
| Source | Best Hit ID | Description | E-value |
|---|---|---|---|
| TAIR | AT5G56580.1 | MAP kinase kinase 6. Encodes a member of the MAP Kinase Kinase family of proteins. It can phosphorylate MPK12 in vitro and it can be dephosphorylated by MKP2 in vitro. | 0 |
| RefSeq | XP_017240238.1 | PREDICTED: mitogen-activated protein kinase kinase 6 [Daucus carota subsp. sativus] | 0 |
| Q9FJV0 | Mitogen-activated protein kinase kinase 6 OS=Arabidopsis thaliana OX=3702 GN=MKK6 PE=1 SV=1 | 0 | |
| TrEMBL | A0A162AMI3 | Protein kinase domain-containing protein OS=Daucus carota subsp. sativus OX=79200 GN=DCAR_012029 PE=3 SV=1 | 0 |
Expression
| BioProject | Accession | TPM | Cultivar | Tissue | Development Stage | Sample Name | Description |
|---|---|---|---|---|---|---|---|
| PRJNA723697 | SRX10692252 | 2.247013 | Shengqin NO.2 | seed | S1-1 | S1-1 | initial formation stage (S1) |
| PRJNA723697 | SRX10692254 | 0.551777 | Shengqin NO.2 | seed | S1-3 | S1-3 | initial formation stage (S1) |
| PRJNA723697 | SRX10692255 | 0.884148 | Shengqin NO.2 | seed | S3-1 | S3-1 | middle development stage (S3) |
| PRJNA723697 | SRX10692256 | 0.57506 | Shengqin NO.2 | seed | S3-2 | S3-2 | middle development stage (S3) |
| PRJNA723697 | SRX10692257 | 1.171912 | Shengqin NO.2 | seed | S3-3 | S3-3 | middle development stage (S3) |
| PRJNA723697 | SRX10692258 | 1.615724 | Shengqin NO.2 | seed | S5-1 | S5-1 | maturation stage (S5) |
| PRJNA723697 | SRX10692259 | 0.604894 | Shengqin NO.2 | seed | S5-2 | S5-2 | maturation stage (S5) |
| PRJNA723697 | SRX10692260 | 1.135671 | Shengqin NO.2 | seed | S5-3 | S5-3 | maturation stage (S5) |
| PRJNA884666 | SRX17729272 | 23.013941 | celery | anther | W99A-r1 | male sterile line | |
| PRJNA884666 | SRX17729273 | 17.954123 | celery | anther | W99A-r2 | male sterile line | |
| PRJNA884666 | SRX17729274 | 22.959476 | celery | anther | W99A-r3 | male sterile line | |
| PRJNA884666 | SRX17729275 | 16.180286 | celery | anther | W99B-r1 | maintainer line | |
| PRJNA884666 | SRX17729276 | 13.752786 | celery | anther | W99B-r2 | maintainer line | |
| PRJNA884666 | SRX17729277 | 14.727992 | celery | anther | W99B-r3 | maintainer line | |
| PRJNA884180 | SRX17743889 | 10.118002 | var. secalinum Yablochny | collenchyma | Col_S1_rep1-1 | ||
| PRJNA884180 | SRX17748056 | 9.135587 | var. secalinum Yablochny | collenchyma | Col_S1_rep3 | biological replicate 3 | |
| PRJNA884180 | SRX17748057 | 8.942589 | var. secalinum Yablochny | collenchyma | Col_S1_rep4 | biological replicate 4 | |
| PRJNA884180 | SRX17748678 | 1.992753 | var. secalinum Yablochny | parenchyma | Par_S1_rep1 | Biological replicate 1 | |
| PRJNA884180 | SRX17748679 | 2.470704 | var. secalinum Yablochny | parenchyma | Par_S1_rep2 | Biological replicate 2 | |
| PRJNA884180 | SRX17748680 | 1.906663 | var. secalinum Yablochny | parenchyma | Par_S1_rep3 | Biological replicate 3 | |
| PRJNA884180 | SRX17748681 | 2.181705 | var. secalinum Yablochny | parenchyma | Par_S1_rep4 | Biological replicate 4 | |
| PRJNA884180 | SRX17748898 | 9.824216 | var. secalinum Yablochny | vascular bundle | Vas_S1_rep1 | Biological replicate 1 | |
| PRJNA884180 | SRX17748899 | 8.221495 | var. secalinum Yablochny | vascular bundle | Vas_S1_rep2 | Biological replicate 2 | |
| PRJNA884180 | SRX17748900 | 14.107392 | var. secalinum Yablochny | vascular bundle | Vas_S1_rep3 | Biological replicate 3 | |
| PRJNA884180 | SRX17748901 | 8.958306 | var. secalinum Yablochny | vascular bundle | Vas_S1_rep4 | Biological replicate 4 | |
| PRJNA884180 | SRX17749129 | 5.472613 | var. secalinum Yablochny | part of the celery petiole without collenchyma strands | Collenchyma-free_S1_rep1 | Biological replicate 1 | |
| PRJNA884180 | SRX17749130 | 6.312416 | var. secalinum Yablochny | part of the celery petiole without collenchyma strands | Collenchyma-free_S1_rep2 | Biological replicate 2 | |
| PRJNA884180 | SRX17749131 | 3.89989 | var. secalinum Yablochny | part of the celery petiole without collenchyma strands | Collenchyma-free_S1_rep3 | Biological replicate 3 | |
| PRJNA884180 | SRX17749132 | 5.122954 | var. secalinum Yablochny | part of the celery petiole without collenchyma strands | Collenchyma-free_S1_rep4 | Biological replicate 4 | |
| PRJNA1124269 | SRX24936411 | 0.615263 | leaf | CK1 | replicate=biological replicate1 | ||
| PRJNA1124269 | SRX24936412 | 1.175935 | leaf | CK2 | replicate=biological replicate2 | ||
| PRJNA1124269 | SRX24936413 | 1.148058 | leaf | CK3 | replicate=biological replicate3 | ||
| PRJNA1124269 | SRX24936414 | 0.265538 | leaf | D1 | replicate=biological replicate1 | ||
| PRJNA1124269 | SRX24936415 | 11.239158 | leaf | D2 | replicate=biological replicate2 | ||
| PRJNA1124269 | SRX24936416 | 0.855748 | leaf | D3 | replicate=biological replicate3 | ||
| PRJNA1124269 | SRX24936417 | 0.363746 | leaf | MD1 | replicate=biological replicate1 | ||
| PRJNA1124269 | SRX24936418 | 0.869637 | leaf | MD2 | replicate=biological replicate2 | ||
| PRJNA1124269 | SRX24936419 | 0.135288 | leaf | MD3 | replicate=biological replicate3 | ||
| PRJNA387092 | SRX2833309 | 14.218797 | shanghaihuangxin | leaf | leaves between 0.5 and 1 cm in breadth, folded; | stage 2 | |
| PRJNA387092 | SRX2833321 | 1.021675 | shanghaihuangxin | leaf | leaves between 2and 2.5 cm in breadth, nearly unfolded, with clear stem exten-sion | stage 5 | |
| PRJNA387092 | SRX2833323 | 0.816418 | shanghaihuangxin | leaf | leaves >3 cm, unfolded, with clearstem extension | stage 7 | |
| PRJNA543957 | SRX5879598 | 0.146615 | Zhangzhou lvqing | stem | Se3 | 100 ppm Na2SeO4 | |
| PRJNA543957 | SRX5879599 | 0.232424 | Zhangzhou lvqing | stem | Se2 | 100 ppm Na2SeO4 | |
| PRJNA543957 | SRX5879600 | 0.53067 | Zhangzhou lvqing | stem | Mock2 | mock | |
| PRJNA543957 | SRX5879601 | 0.819836 | Zhangzhou lvqing | stem | Mock1 | mock | |
| PRJNA543957 | SRX5879602 | 0.108577 | Zhangzhou lvqing | stem | Se1 | 100 ppm Na2SeO4 | |
| PRJNA543957 | SRX5879603 | 1.134289 | Zhangzhou lvqing | stem | Mock3 | mock | |
| PRJNA609149 | SRX7815917 | 14.171227 | Jinnan Shiqin | flower bud | early flower bud | early flower bud | |
| PRJNA609149 | SRX7815918 | 14.37223 | Jinnan Shiqin | flower bud | middle flower bud | middle flower bud | |
| PRJNA609149 | SRX7815919 | 13.053027 | Jinnan Shiqin | flower bud | early flowering period | early flowering period |
Orthology
| Family | Species | Count | Orthologous Genes |
|---|---|---|---|
| Acanthaceae | Avicennia marina | 3 | jg15466, jg31736, jg32898 |
| Aizoaceae | Mesembryanthemum crystallinum | 3 | gene_11012, gene_20263, gene_9128 |
| Amaranthaceae | Atriplex hortensis | 2 | Ah014671, Ah015217 |
| Amaranthaceae | Beta vulgaris | 1 | BVRB_8g197680 |
| Amaranthaceae | Salicornia bigelovii | 4 | Sbi_jg24606, Sbi_jg25090, Sbi_jg8465, Sbi_jg8935 |
| Amaranthaceae | Salicornia europaea | 2 | Seu_jg19661, Seu_jg20125 |
| Amaranthaceae | Suaeda aralocaspica | 2 | GOSA_00007709, GOSA_00014721 |
| Amaranthaceae | Suaeda glauca | 5 | Sgl42327, Sgl42365, Sgl42890, Sgl47105, Sgl47682 |
| Amaranthaceae | Chenopodium album | 5 | gene:ENSEOMG00000008912, gene:ENSEOMG00000032709 ... |
| Amaranthaceae | Chenopodium quinoa | 4 | CQ.Regalona.r1.8AG0015050, CQ.Regalona.r1.8AG0019160 ... |
| Anacardiaceae | Pistacia vera | 3 | pistato.v30101160, pistato.v30257500, pistato.v30259710 |
| Apiaceae | Apium graveolens | 2 | Ag10G01498, Ag8G00267 |
| Arecaceae | Cocos nucifera | 3 | COCNU_06G004630, COCNU_14G003050, scaffold001333G000030 |
| Arecaceae | Phoenix dactylifera | 3 | gene-LOC103711214, gene-LOC103714344, gene-LOC103720812 |
| Asparagaceae | Asparagus officinalis | 2 | AsparagusV1_02.243.V1.1, AsparagusV1_06.835.V1.1 |
| Asteraceae | Flaveria trinervia | 2 | Ftri4G18858, Ftri8G12609 |
| Brassicaceae | Arabidopsis thaliana | 3 | AT4G26070.2, AT4G29810.2, AT5G56580.1 |
| Brassicaceae | Eutrema salsugineum | 3 | Thhalv10013956m.g.v1.0, Thhalv10025480m.g.v1.0 ... |
| Brassicaceae | Schrenkiella parvula | 3 | Sp6g18360.v2.2, Sp7g24080.v2.2, Sp7g27620.v2.2 |
| Brassicaceae | Brassica nigra | 4 | BniB02g035590.2N, BniB02g082260.2N, BniB05g007900.2N ... |
| Casuarinaceae | Casuarina equisetifolia | 2 | Ceq06G0825, Ceq06G1572 |
| Casuarinaceae | Casuarina glauca | 2 | Cgl06G0849, Cgl06G1631 |
| Cymodoceaceae | Cymodocea nodosa | 2 | gene.Cymno01g10150, gene.Cymno01g12740 |
| Dunaliellaceae | Dunaliella salina | 1 | Dusal.0024s00003.v1.0 |
| Hydrocharitaceae | Thalassia testudinum | 2 | gene.Thate02g01380, gene.Thate06g15760 |
| Malvaceae | Hibiscus hamabo Siebold & Zucc. | 1 | nbisL1-mrna-175 |
| Nitrariaceae | Nitraria sibirica | 2 | evm.TU.LG07.1168, evm.TU.LG07.1271 |
| Plantaginaceae | Plantago ovata | 3 | Pov_00003434, Pov_00004087, Pov_00039602 |
| Plumbaginaceae | Limonium bicolor | 4 | Lb0G37148, Lb3G16941, Lb7G34232, Lb7G34243 |
| Poaceae | Echinochloa crus-galli | 5 | AH02.3013, AH06.245, BH02.3104, CH02.3419, CH06.340 |
| Poaceae | Eleusine coracana subsp. coracana | 6 | gene-QOZ80_1AG0031520, gene-QOZ80_1BG0081640 ... |
| Poaceae | Hordeum vulgare | 2 | HORVU.MOREX.r3.4HG0408170.1, HORVU.MOREX.r3.7HG0650300.1 |
| Poaceae | Lolium multiflorum | 2 | gene-QYE76_027869, gene-QYE76_070752 |
| Poaceae | Oryza coarctata | 4 | Oco01G011080, Oco11G002250, Oco12G002240, Oco21G003470 |
| Poaceae | Oryza sativa | 2 | LOC_Os01g32660.1, LOC_Os06g05520.1 |
| Poaceae | Paspalum vaginatum | 5 | gene-BS78_03G260300, gene-BS78_09G016300, gene-BS78_K316300 ... |
| Poaceae | Puccinellia tenuiflora | 3 | Pt_Chr0402217, Pt_Chr0601959, Pt_Chr0604121 |
| Poaceae | Sporobolus alterniflorus | 11 | Chr01G013590, Chr02G010900, Chr05G022710, Chr0G015680 ... |
| Poaceae | Thinopyrum elongatum | 3 | Tel4E01G521200, Tel6E01G175000, Tel7E01G199500 |
| Poaceae | Triticum dicoccoides | 5 | gene_TRIDC4AG055280, gene_TRIDC4AG057520 ... |
| Poaceae | Triticum aestivum | 6 | TraesCS4A02G396700.2, TraesCS4A02G414600.1 ... |
| Poaceae | Zea mays | 2 | Zm00001eb154530_P002, Zm00001eb377050_P001 |
| Poaceae | Zoysia japonica | 2 | nbis-gene-18350, nbis-gene-26330 |
| Poaceae | Zoysia macrostachya | 3 | Zma_g11039, Zma_g27586, Zma_g31353 |
| Portulacaceae | Portulaca oleracea | 6 | evm.TU.LG02.2355, evm.TU.LG02.2787, evm.TU.LG05.1535 ... |
| Posidoniaceae | Posidonia oceanica | 2 | gene.Posoc03g19830, gene.Posoc03g23750 |
| Rhizophoraceae | Bruguiera sexangula | 4 | evm.TU.60383.2, evm.TU.60384.2 ... |
| Rhizophoraceae | Carallia pectinifolia | 2 | nbisL1-mrna-25697, nbisL1-mrna-25765 |
| Rhizophoraceae | Ceriops tagal | 3 | nbisL1-mrna-12788, nbisL1-mrna-19076, nbisL1-mrna-20187 |
| Rhizophoraceae | Ceriops zippeliana | 3 | nbisL1-mrna-16930, nbisL1-mrna-4606, nbisL1-mrna-4664 |
| Rhizophoraceae | Kandelia candel | 3 | evm.TU.utg000008l.1022, evm.TU.utg000008l.1076 ... |
| Rhizophoraceae | Kandelia obovata | 3 | Maker00000139, Maker00001006, Maker00014709 |
| Rhizophoraceae | Rhizophora apiculata | 3 | nbisL1-mrna-14806, nbisL1-mrna-14862, nbisL1-mrna-4003 |
| Rhizophoraceae | Rhizophora mangle | 3 | nbisL1-mrna-1108, nbisL1-mrna-1175, nbisL1-mrna-8163 |
| Salicaceae | Populus euphratica | 5 | populus_peu05006, populus_peu05071, populus_peu05072 ... |
| Solanaceae | Lycium barbarum | 3 | gene-LOC132633142, gene-LOC132633281, gene-LOC132636897 |
| Solanaceae | Solanum chilense | 2 | SOLCI000531800, SOLCI004334900 |
| Solanaceae | Solanum pennellii | 2 | gene-LOC107007412, gene-LOC107012802 |
| Tamaricaceae | Reaumuria soongarica | 2 | STRG.17970_chr09_-, gene_8038 |
| Tamaricaceae | Tamarix chinensis | 2 | TC10G1509, TC10G1808 |
| Zosteraceae | Zostera marina | 2 | Zosma05g24860.v3.1, Zosma06g00660.v3.1 |