>Sgl00010 E3_adaptor/Cullin_RING/DCX/DWD 92.7 28.3
MEIDFQDYQLSAQLHGHEDDVRGICVCDNAGIVTSSRDKTVRFWPLDSANNYKEMPSPKI
MVGHTSFVGPLAWISPNDEFPEGGIVSGGMDTLAMVWDLKSGERVHVLRGHQMQVTGIAL
DDHDIVTSSVDCTLKRWRNGKVVDSWEVHSSPVQAVIKLPSGELATGSSDTTLKLWKGKT
CVHTYTGHSDTVRGLAVMSDLGVISASHDGSVRLWALTGEVLLEMVGHTSIVYSVDSHVS
GLVASGSEDCSAKIWKDGVCVQSIEHPGCVWDVKFLENGDLVTACSDRVVRIWTTHADRM
ADPVERDSYSSLLSNYKISRKTVGGLKLEELPGLDSLQVPGTSDGQTKVVREGDNGVAYT
WNMKDYKWDKIGEVVDGPGDGLKRPVLDGKEYDHVFDVDIGDGEPIRKLPYNRSDNPYDT
ADKWLLKENLPLSYRQQVVDFIMENTGQKTFSFDSSFRDPYTGSNAYVPGQTSTNNAVSA
KPTYKHIPKKGVLVFDVAQFDGILKKLSEFNNTLLSDEDQKQFSLTDVETSRIGAVVKIL
KDTSHHHSSSFADVDIELLFKLLTSWPVAMIFPVIDIMRMVILHPDGASKLFKHVNGGND
ALMEIIKKVTTDPVIPGNVLTGLRALTNLFKNTCFHQWLQTHRSEILDAFSCCYNSNKNA
QFAYSTLILNFAVLLIEKRDEEGQSQVLSAALEIAETENLDVESKFRALVAIGSLMLDGS
VKQIALDFDVESIAKGAKSSKDTKIAEVGADIEVVANGS
>Sgl00020 E3_activity/RING/RING 24.9 14.8
MAAKPPEHEHHPSSFPPATSFSSSSILIHQSSTIDFSPPLIAMVVVAAAAFLFITYSRRI
SRHIFPPFLRLYRHHRRRARRFLPSSDLASPPAPYQSSSDGFYVYSPCPYGLDDSTIKNI
PLTKLKFIELLDEDGFHFHDCAVCLVDFQEGECIRTLPHCCHPFHVDCIDMWLRSHATCP
LCRAGVFLSPPPDDSHSHPHVQLSPVMAARVRPSFDQGILLESMFLEHLQEGNNSEEIQE
IFSPESERRAIQSERSSNNRRELDSLLKRSYSFGFERRGSYPSVSEERLVMEPATTPYHH
HRQRRSFFWRKRPSSSTPFRSMAKSRVFSFRRTMKSQSQSQSPAFFRRKGYISMWESSES
LRYGSSRRMKASPGPFSSSRMRLGDPEALISPERYNRHRR
>Sgl00078 E3_adaptor/Cullin_RING/BCR/BTB 69 0.0
MGSKEWQGKENSSDRKGQKRKLEQQQDERDSAIVTDEALRREVRTQVDILSANFSWSEVD
RASAKRATHLLAELAKNEEVVSIIVEGGAVPLLVKHLEAPPSSGEDDGLKPCEHEVEKAS
AFALGLLAVKPEHQQLIVDVGALPLLVDLLKRHKCGVNSRAVNGVIRRAADAITNLAHEN
SSIKTQVRTEGGIPPLVELLEFNDAKVQRAVAGALRTLAFKNDENKKQIVECNALPSLIL
MLKSEDAAIHYEAVGVLGNLVHSSPNIKKEVLLAGALQPVIGLLSSCCSESQREAALLLG
QFAATDSDCKVHIVQRGAVPPLIEMLQSSDLQLREMAAFALGRLAQESHNQAGISHSGGL
VPLLKLLDAKNGSLQHNAAFALYGLADNEDNVADFIKAGGLQKLQEGEFIVQATKDCVAK
TLKRLEEKIHGRVLTHLVYLMRAGEKAVQRQVALALAHLCSPEDQRSIFIDNNGLELLLG
LLKSTSSKQQHDGAVALCKLASKAMTLSPVDAAPPSPISQVYLGEKYVNSATLSDVTFLV
QGKRFHAHRICLLASSDAFRAMFDGGYRERDARDIEIPNIRWEIFELMMRFIYTGSVDIK
PDIAQDLLRAADQYLLDGLKRLCEYTIAQDISLDNVSSMYDLSDAFHAVSLRQACILFIL
EQYEKLNAMPGHSSLIQHILPEVRNYFLRILTKPNA
>Sgl00258 E3_adaptor/Cullin_RING/DCX/DWD 42.3 1.4
MLTIIGPLKNATHPRLTFLCGGGSHRFSVELDCEKIQLHNQLLTSNQGFPKVMRDYKIGN
YNKVNQSSFNSRFLAKSNRCLLQDFHGHVADVLDLAWSDSNVFQFLLSSSMDRTVRLWKL
GSDVCLNIFHHTNYDNRYFISGSIDGKVRKWGVLEQRVLDWAEIKDAVTTACYQPNAQAF
VVGSLNGSCIFYETKRELFELSAHVQLYNSKRSATKRITGIQFSPKDSKIKKHGATRR
>Sgl00282 E3_adaptor/Cullin_RING/DCX/DWD 31.3 0.0
MKAKAVKLREAHSSISIYESLLLSTPMKNLRHHRDGVTALALSPNSTCLASGSIDRTVKL
YKFPRSLLAVAGDDEGIKLINTVDSTIARVLKGHKGPITSLASF
>Sgl00283 E3_adaptor/Cullin_RING/DCX/DWD 24.7 0.5
MVIFLSVPGLKNDVIMYDRDTAELQYYIRCDHVKPISALSWSPNGRYLATSDSDNQVLIW
DVDKRLDIDRQQFDERICSMAWKPTGNVLAIIDVMGKYGVWESVIPSSMKSPTEDVLQSK
YNNGLLLFDEEEQEQSTSASFSDMGEDNFVESMPHTKKRLRKSSLYEESLEKDIISEELD
SHQRIKSHRKPAKNHKECLDGGDGKPKSMTVQNFSKLQEPFQPGATPVQPGTKCFLCCNM
LGSITIMQHDGNSHIEIYFHDKSQGPRVPAMTDYFGFTMASLNENGSALANPRNGEKNST
LMYRLFSSWANNSEGNNDTMLNLLSLRRKRLCIVIKQIPQLLQLHYSYRECYFGRRNSST
SFSLSLCTNLFLVFERYVQITLILNSASYPL
>Sgl00345 E3_activity/RING/RING 25.3 11.1
MTTTDDELTKQLLQLRTQLNKKQTFESAISSIKSLLIENYPNSSPPIKTLFYDVVCRVAT
VLRTRYTFPGYLVAGVELLETAEKLIAIPSEKSHLKSCISNIRQTLNQDDENEEPLQRNS
NGGYLFEGHLTVDQEPPQPNWLVQQNLLTALASSQSQPNGENSDTVSSLMRGLVESLDVS
MIENLEEILPLMEGDGVGSRAAPPASKEVVGKLPVIKVESEEMLKNKFGGEGAECCICKE
KLGVGDEMQEMPCKHLFHPPCLKPWLDEHNSCPICRHELPTDDHKYESWKEREKELEEER
RGAANAVRGGEFMYI
>Sgl00365 E3_activity/RING/RING 28.9 9.8
MAEFSTKLKESLILSMSPSTTPGSTIDDDFEDACSICLEPFSPHDPASVTTCKHEYHLHC
ILEWSQRSKECPICWQTVALKDSASQELLVAAEIERKARARRASTNRTTYSYQYQEPDTG
YDSHWTDESDFNERMMQQLAAMMSRARQAHRSGRQRSSGRSPSPDPEIMFPSRGSESALH
PNTPEECNSAYGSPGGSSPTASTQPQFPAIQLSANLSSGSAPRRVVNQPSRPPQSQSPDS
SQRQRSSELLAFSESIKSKFSAASARYKDSISKGTQGFREKILARNSSVKELSKGVQREM
NASIAGVTRMIERLDLKSKRGTQSGDDNHGGETSTLMSKGKGVLDHILASSQENCVATGH
ENSQATCSISSHKDVAREQRT
>Sgl00373 E3_adaptor/Cullin_RING/SCF/F-box 20.2 0.0
MEAFPPEIIEEILSRLPVESLLCLKTVCKSWNSIIKTPAFIKSHLNKTLISNSHPRLLKS
STDYLKEKKLSLYSAKIDSDDSQTDDRRLSFSMLNHPPDEFNSGTVFGSCNGVVSIYDYS
KTNVLLYNPFTKSRRILPAKALPPSYKSKMGGRMLYGFGYDSKTDDYKVLRIAQGYRSLD
HPFNETDHVCSVYSLNNDCWKSVYGIVSKQYYFFLYTYDGVFFNETLHYLMISTTY
>Sgl00384 E1 303.9 0.0
MHTDLDIVELEQSLTDISMADSTANSRSRDLDKLLLRAGHLVGPNFQPGSELRDDIQEYA
RVLVVGAGGLGCELLKDLALSGFKNLDVIDMDTIEVTNLNRQFLFRLEDVGKPKAEVAAK
RVMQRVSGVNIVPHFCRIEDKPLDFYNDFNIIALGLDSVEARSYINAVACSFLEYDENDN
PKEETIKPMVDGGTEGFKGHARVIIPGKTPCFECTIWLFPPQVKFPLCTLAETPRTAAHC
IEYAHLIKWDEVHSGKAFDPDDPDHMQWVYQEAVKRAELFGIPGVTYSLTQGVVKNIIPA
IASTNAIISAACALETLKLVSGCSKTLSNYMTYNGVDGLHTKVTEFSKEKDCLVCGPGVL
IELDASCTLQKFIEQLEEHPQLHLSKASVTYEGKNLYMQAPPVLEEMTRSNLSQPLFELM
EKVSSGTIHATGTSSKNDKKTFGSRKLRVTFKGVDGMTDMDTAGGA
>Sgl00410 E3_activity/RING/RING 25.3 11.1
MTTTDDELTKQLLQLRTQLNKKQTFESAISSIKSLLIENYPNSSPPIKTLFYDVVCRVAT
VLRTRYTFPGYLVAGVELLETAEKLIAIPSEKSHLKSCISNIRQTLNQDDENEEPLQRNS
NGGYLFEGHLTVDQEPPQPNWLVQQNLLTALASSQSQPNGENSDTVSSLMRGLVESLDVS
MIENLEEILPLMEGDGVGSRAAPPASKEVVGKLPVIKVESEEMLKNKFGGEGAECCICKE
KLGVGDEMQEMPCKHLFHPPCLKPWLDEHNSCPICRHELPTDDHKYESWKEREKELEEER
RGAANAVRGGEFMYI
>Sgl00440 E3_adaptor/Cullin_RING/SCF/F-box 12.5 0.0
MSVQGENICPLSSDVFYDILRRLDGATLASAACTCAAFSSISKEERIWEDVCYSLWPSTK
NDDVSNLIRSMGGFRKFYADCYPLIVNNDLALVPLDTFLEYPEEWPEADYYEDLEEYDSV
SPSDFVSLVDIRYKDKPIYSKVLPGFSDSDVLGRWFYNSPFHIDLGKSDVSDSVGEVIIS
VADGLPPIKSIDDERKDGKVWLELQDRLRLSWIIINKKVKQAANISSLIPLGVQRHWPSD
TDFLVRFGSVLPAGDILPCQVVECIFLAKFRMFDDSASGCINLELTQVSMQLEDMEGFHV
NGRNSLMVLKKALSCRKSKNYSEVLESCNLYSRVRSEIKEEKLRNESRIDKMCILSGVLA
VVTFWFCIL
>Sgl00555 E3_adaptor/Cullin_RING/DCX/DWD 19.8 16.2
MDDEDKDMLYSFSNTPPPNRKAHSLSTHLRYGTNTNNPSNSTPTSSTTPNANPELSSSSS
KRANQLRNHSLDEARITNAITNHHQNRHLGGPFYNTDYSDEDADFFPYASSSMSTTFARC
YDHSVSLPAVGSSEPEDDDHRISMPEFTANGGTGIFKAPTRSAVHPTRPPALELRPHPLR
ETQVGRFLRTIGCTESQLWAGQENGVRFWNFRDAYEAGVGFAGRNTKRGDEDTSPFYESA
VTSPTLCLVVDHGNRLVWTGHKDGKIRSWKMDQNVNNSNGGDGGGGNGNGGGGGSEDSSP
PFREGLAWQAHKGPVLALIISCYGDLWSGGEGGVIKIWPWDSIEKSLSLSAEEKHMAALL
VERSNVDLRSQVTVNGVCNISSSDVKAMLSDHARGRVWCATSLSFSLWDARTKELVKVYN
IEGQIENRAEMPVPQDQQPAEDEMKVKFVSQSKKEKPQGFLQRSRNAIMGAADAVRRVAT
RGTGAFNEDTKKTEALLLTSDGTIWSGCSNGLILQWDWNGNRVQEFNHHPSAVLCFCTHG
PRLWVGYASGVVQLLDLEGNLIAGWVAHSSPVIKMAIGGGYVFSMAIHGGIRGWHLTSPG
PLDNVIRSALSAKELLYTRKESIKMLVGSWNVGQGKPNPEGLKSWLGSAVSDVGIVVVGL
QEVEMGAGFLAMSAAKETVGLEGSAIGQHWQDAIGRVLDEGMVFERVGSRQLAGLLIAIW
VRKNLRMHAGDLDVSAVACGFGRTIGNKGGVGLRLRVHDRIICFVNCHLAAHLEAVNRRN
ADFDHIFRTMVYSRQSHLLNVAAGMRCLLLYCSLALCIYLFWLLYSSGFPLLLSLAAGAS
SASQVIRTANGANGNSDEGGRPDLSEADMVVFLGDFNYRLFGISYDEARDFVSQRSFDWL
REKDQLRAEMKAGKVFQGMREAMIKFPPTYKFERHVPGLGGYDSGEKKRIPAWCDRVIYR
DCRTGPVSECSLNCPILASIQMYEACMDVIDSDHKPVRCKFSVHLARVDRSIRRKEFGEA
MNTSEEIKTIIRNISEIPETEVSTDNITLQNQDTSVLQITNNSQNEKAVFHIICEGVCII
NVNGEPSELRPRASFGFPFWLEVTPSCGVIYPEQSMEVTVRHTESHTLGDLVEGVPQNWW
SEDTRDKEVVLAVQVRCNSTMELSSHRIRVRHCYSARTSRTDSSRTNSSRRGNNGSHYRS
ESQRRDNNPDMVDRG
>Sgl00558 E3_adaptor/Cullin_RING/SCF/F-box 17.6 0.0
MMETSKHPNTNNGDKQDLLSSLPEEILIKILSYLPIEAAVTTGVLSRRWQHLWTLVTAFD
FNNLTVGKPIDQVPSIINHILPQLKSPQLQTFVIHLDDQSPPVTDNNAFDLGDQHDKHLK
LLSKFCSHIGSWIKLLCNRKVQVIEVLVFGRFIASCSATLPSCIFQCESLESLALNMPLR
VTLPKYISLPNLKVLYLSHLNEKHRQLLGKLLNSCPCLEDLSLAGYIDNPTVEGHEISVV
IASENLDALYIGLWKVSRGDMLVNVDAPKLKYLRVDDISRSRVKFIKEPSDLSEASLGTN
FMNPGLTLGMDLFGVIRNVRSLVIDSVTIDAFNRLYDDQANSSVVSQGFCSLTELVCYKM
SPACWKQLTCLVSCAPKLESLTYEIKVTGFYSDLNINDVFVHVNDAPQFPLQHVKRVEMR
ECFGRTVDDTMMDFIKYCLSNASVLEQFDVKLPVTGTESSDSIELLKRNELELCEILCNL
PRSSVSCRIEVSSWCASTESIG
>Sgl00645 E3_adaptor/Cullin_RING/SCF/F-box 19.5 0.0
MAELPTDIIIKILSKLPVKSLLRFQCVSKSWKSLIKSPNFINSHLNQTLISFSNRHLLIS
AIHTSLHSSELDHLLINNQLALSFSQLHPPLKPFNFVGSYNGVVCISDISQNNFFLFNPL
TNSRHKVPTSKIQVPEFNLMVFGFGYDRINDDYKVLRIVQGVGMLDGSENNALVYSLKAN
SWRFIKSIQFYLYHGYCHGAFVNENLHYLVTKEPDYLSVFIAIFDVRTESFSVMDCPDYD
HHRFVSNSLNTAFMLVELGGCLCLLMSSYVGDGGGVGDEVMVAPAEYIDELDARVLDCVD
FWVMKEYGNNESWVRLFSIRHPESIGSYKLIKPLVYSNDGSRILLEIDNSRYIWYDPKSK
IVERISVHGVLSNGGLKAGIFIGSLVSLEDKVVPQKEGLLMKKSKKNDVEDRFLSKGFKL
KL
>Sgl00646 E3_adaptor/Cullin_RING/SCF/F-box 19.3 0.0
MAELPTDIIINILSKLPVKSLLRFQCVSKSWKSLIKSPNFIKIHLNQTLTSYSNRHLLVS
VEYSSLHSSEFDLTNNPPSLCFSALNPPHEKFHFVGTYNGIVCISSISKRENFLFNPLTN
SCHKLPSAEIPIPEFNMTLLGFGYDRNNDDYKVLKIIQGLGKLDDSKNKAQVYSLKNNSW
KCIQGIPYALYYGYYDGVLVNDYLHYVVTHEPSSEHLLIASFDLLTESFSHMECPDYDDQ
FTSFHSVFTLVELGGCLCLLINFYGNDEMLFDDDDDDLLDELDARVLKCVELWVMKEYGK
KESWVRLFAIRHPETMGSSRVIRPIVYSEDGRRILLEIDVLRYGWYDLESKNFDLINAHG
LPKGLINTKVFIGSLVSLEVEDKLLSQKEAVPMKNNKKKNVDNFLSDGFKLKL
>Sgl00647 E3_adaptor/Cullin_RING/SCF/F-box 18.7 0.0
MATLPTEQITEILSRLPVKSLIKFTCVCKSWYSLIKSPKFIKLHLNQTLISNSNRFLLIS
YSSKQSSNNNLCRNHLVLSEFDTNPNDNQLKYSEIHHPLNHREITLLGDCNGVVCITDKP
KNNVFLYNPMTKSCRKLPRNRTSKNNFDNQSLVFGFGYDPETDDYKVLRLLQDSHYNDVN
YKEAELYSMRNNSWKYVEKIPYFLLFLDRHGVYLNGAIHFVVVTAELQMHRKFIASFDFK
TESYSLMECPDYGDKLGASLDMGEISGCLCLMVMDRIILPFDEIGFRMDSAELWVMKEYG
KSESWVRVFSIPATATSVGMYLHARPLAYSKDGKKVLIEYDYLGIGWLDLETQKFVMSEG
VPKPPIFSRVFQGSLVSVGDDKLKFEEAAAIPRKNTKKKNVDNFLSSGFKLKL
>Sgl00651 E3_adaptor/Cullin_RING/SCF/F-box 13.8 0.0
MEALPPVIIEKILSGFPAESLLCLKTVCKSWNSIIKTPAFIKRHLNQTLISNSHRRLLKS
LKDNSQNRKLSLYSAEIDSDSPTIDRRLSFSMLNYPLDEFVHATVFGSCNGVVSIREHSR
TNNVLLYNPFTKSRRILPPEGLPLSYKSERDRRLLYGFGYDSKTEDYKVLRIVQGYSFNE
VDGHVCSVYSLNNDCWKSVNWIVSKHFYFFPYPCSDGVLVNENLHYLVMSSTNESMIVCF
DLPTESLSLMDFPNNLMMSGCESSLAEFDGCLCVMCMYFTLNNILVRAD
>Sgl00686 E2/UBC 102.8 0.0
MTSLSGDTTNPDEKFPQFDAVPDASDHHFAGKHQNPSFSSSNSALHKKIMQEWKILSKDL
PETIFVRVYETRVDLLRAAIVGARGTPYHDGLFFFDIAFPSDYPSKPPLVHYHSFGLRIN
PNLYSSGKVCLSLLNTWSGKKSEKWDPNNSTILQVLVSIQALVLNERPYFNEPGYSAWSG
RTYWEKKSLAYSEDVFLLSCKTMLWVLRRPPKKFEPLVNQHFKERAQFLLTACDAYRKGC
VKIGSFETVSWRVKGVETSVKFKGLMNQLYGDLVIAMSKTGASVGQRVEQVREEKEKNAN
EKAVAAAKKKQGEINVSEVGKNVVKKLKKIVFHGLMIKNKNGKSKEIINKNEISKEISV
>Sgl00721 UBD/UBC-like/UBD_UBC 62.5 0.0
MAAVDKYNLKNPAVKRILQEVKEMQSNPSDDFMSLPLEENIFEWQFAIRGPRETEFEGGV
YHGRIQLPADYPFKPPSFMLLTPNGRFETQTKICLSISNHHPEHWQPSWSVRTALVALIA
FMPTAPNGALGSLDYKKEERRDLAIKSREMPPKFGTAERQKVIDEIHAYMLSKAPPVPEN
LKQASAEHVGETEAEVETQTEGSENAGTSAATVEPENAGDERVVEEAQADGENVNPVIHR
EAIHRQVRTDIPNQQLQHRPAARVQKPGDDRLLTWAAVGLTIAIVFLLLKKLAKSSGYGA
LFLSES
>Sgl00753 E3_adaptor/Cullin_RING/SCF/F-box 21.1 0.0
MEAFPSEIIEEILSRLPAESLLSLKTVCKSWNSIIKNPSFIKSHLNQTLISNSHRRLLKS
PKIMDYSKKRKLSLYSAEIDSDSATADRRLSFSMLNHSLDDYVEVFGSCNGVVSVCNYSR
TSVLLYNCFTKSRRILPAERLPPGYKSERGRFFYGFGYDSKTDDYKVLRIAQGYRSLVYP
FYETDHICSVYSLNNDCWKSIHGIVSKQYYYFPYPYSHGVLANETLHYLVTSNISYELDD
LKRPGRMIVCFDFRTESFSLMDCPNHEDENNNDNNNNNLMIRSCKSTYLAELDGCLCSMF
THFSMNYITRERPVFVRADLLVMKEYGNKESWSKVFSINGDQLNIVCRSFTGVKPVVYSK
DRRRILIDINGGIVTGWFDLETKKFEELEHHGLPDEYFDTRYFMGSLVSVGHSKLHSIGT
TEETKTEEKVKK
>Sgl00754 E3_adaptor/Cullin_RING/SCF/F-box 18.8 0.1
MEEFPPEIIEKILSQLSAESLLCLKTVCKSWNSIISTHEFIKTHLNQTLISNSHRRLLKS
SMDSKKRKLSFYSADLDSDSRTDRRRFSYSMLNHPLEVDYATVFGSCNGVVSILDFSKPD
NVLLYNPFTKSRRILPAPSYNNNNNKWELVDLLYGFGYDSKTEDYKVLRIVEKYRYLVNP
PKSFYEADHVCSVYSLNKNCWKSVSGTVLNRYAFSSPSSHCVLVNETLHYLVMSTANDYP
RRMIVCFDLQTDSSSLMDCPNHDDKNNNNLIGRRDSYLAELDGCLCVMFMYFSMNNYNVR
ADLLVMKEYGNKESWSKVFSIRNDQLTSVCTSFRRIKPITYSKDRRRILIDIDGGFVTGW
FDLESKKFKKHKHRGLPFRHFDTSSFMSSLVYINESLFYLKHVLGMYIYSLLFRLTVESG
IEFGNNWNVMGAWDDSLQHAAASLVGMGAALLQEAAACAS
>Sgl00770 UBD/UBC-like/UBD_UBC 112.8 0.0
MKLCPREVEKLALHNAGFLAQKRLASGLRLNYTEAVALIATQVVVHSEKFYNFRSSVFID
FEFCSCWKQECGGTDGHWKEASWKGPSETPYDGGVFQLAFAVPEQYPLQPPQVRFLTKIF
HPNVHFKTGEVCLDILKNAWSPAWTLQSVCRAIIALMAHPEPDSPLNCDSGNLLRSGDLR
GFQSMAKMYTRLAAMPKKG
>Sgl00803 E2/UBC 102.8 0.0
MTSLSGDATNPDEKFPQFDAVPDASDHHFAGKHQNPSFSSSNSALHKKIMQEWKILSKDL
PETIFVRVYETRVDLLRAAIVGARGTPYHDGLFFFDIAFPSDYPSKPPLVHYHSFGLRIN
PNLYSSGKVCLSLLNTWSGKKSEKWDPSNSTILQVLVSIQALVLNERPYFNEPGYSAWSG
RTYWEKKSLAYSEDVFLLSCKTMLWVLRRPPKKFEPLVNQHFKERAQFLLTACDAYRKGC
VKIGSFERVSWRTKGVETSVKFKGLMNQLYGDLVIAMSKTGASVGQRVEQVREEKEKKAN
EKAVAAAKKKQGEINVSEVGKNVVKKLKKIVFHGLMIKNKNGKSKEIINKNEISKEISV
>Sgl00844 UBD/UBC-like/UBD_UBC 62.5 0.0
MAAVDKYNLKNPAVKRILQEVKEMQSNPSDDFMSLPLEENIFEWQFAIRGPRETEFEGGV
YHGRIQLPADYPFKPPSFMLLTPNGRFETQTKICLSISNHHPEHWQPSWSVRTALVALIA
FMPTAPNGALGSLDYKKEERRDLAIKSREMPPKFGTAERQKVIDEIHAYMLSKAPPVPEN
LKQASAEHVGETEAEVETQTEGSENAGTSAATVEPENAGDERVVEEAQADGENVNPVIHR
EAIHRQVRADIPNQQLQHRPAARVQKPGDDRLLTWAAVGLTIAIVFLLLKKLAKSSGYGA
LFLSES
>Sgl00853 E3_adaptor/Cullin_RING/DCX/DWD 86.9 19.1
MMFNKGNMALEKHFPASNLIANGKSLTFPLKIREKVALGDPEMSPETEADIDVDLREVYF
LIMHFLSGGPCQRTYGQFWNELLEHDLLPRRYHSWYSRSGVPSGDENDDGLSCPLSYNKL
VERYSHIDKDHLIKLLKQLLLSKVILPHGVATRNVPNAADVPTLLGAGSFSLLGYDENKG
DNAVHVQLQPVHMRWPHMRADQVRALRLREIGGGFARHHRAPSTRAACYTIAKPSTMVQK
MQNVKKMRGHRNAVYCAVFDRSGRFVITGSDDRLVKIWSMETAYCLASCRGHEGDITDLA
VTSNNAMVASSSNDCIIRTWRLPDGQPISVLRGHTGAVTAIAFSPRPSAVFQLLSSADDG
TCRLWDARYSQFKPRIYLPKPPDSVAGKSVTAPPIAGEQNYQIFCCAFNATGTVFVTGSS
DNLARVWNACKSGADDSEQPIHEMDVLSGHENDVNYVQFSGCAVTSRCSASDTFKEENFP
KFKNSWFGHDNIVTCSRDGSAIIWIPRSRKSHGRAGRWMRAYHLKVPPPPMPPQPPRGGP
RQRVPQTPRGVNMIVWSLDNRFVLAAIMDCRICVWNAADGSLVHCLTGHTESTYVLDVHP
FNPRIAMSAGYDGKTIIWDIWEGKPIRIYETGRFKLVDGKFSPDGTSIILSDDVGQLYIL
STGQGESQKDAKYDQFFLGDYRPLIRDTHGNVIDQETQIPPYRRNMQDLLCDSSMIPYPE
PYQSLYQQRRLGTLGIEWRPSSVRFAVGPDFSSDQDQILPLPDLDVLIDPLPDFMDVMEW
EPEVEVISDDTDSEFNVTESFGGDGRHISSTSSGNSECGEEDSEMECRNKDGVRRSRRKK
KRETEITTSSGRRVKRRNLDECEGSSHRVYQHKKSRAGRKRSRKKSSKASRPQRAAARNA
LTLFSKIKGTPDQDEYCSPDDSSESESELEDSNIESEESDRFALDERAKNLKGKEVVMDD
SVDVSGFKEFPENAWNKKRLILKFPVRDSSRALLSGSSIPTSGNLTDLAGSSSSASGGPV
EFDGKDSAQDRNGVLGNGNLCGYGRLGWLGGYGYNSMKWGGVRARTSKRTKFSEAQPLNA
SGSSCFSDNQVEADNVPCADLKPESEQSGGSGKLQEDAQLGHEHQGNSNGLTDANIELSA
LNRSVSSNEIEDEVHVAVENGALSSKSSDENNVSTWLSSATKKDTLDSDDPSEIKGECGE
GNERNGASSLEQRSGGEEVKEENQHQEADVDGGDCNGARKVDGTNANASFEISNSQVSHL
QKKDKMYSAVYKRSRSFKTRTSSDSNGGLIGENTSNVSCQNQNGNADTKGIMVDGIDQAH
PLEARDTTQDLVNPRRTAGRSRRTEKSSLKKFDRRSREEWGSSTTLGPRSTRNRRVNFVR
NASPVDRRKASQSQRKLSWLMLSVPDCSRYIPQQSDEVAYLRQGHQEYISSNNSYGRGPW
EQLRGEIRAVEFCKVIVLEYSIVPGSGESCCKMTLEFTDPNSSVYSKTFQLTLPEVSNFP
DFLVERTRYETAMERKWTRRDKCQVWWRNEGDGDGSWWEGRISEVKLQSLDFPDSPWEKY
VVRYKSDPTEEHSHSPWELHDPHDAQWEQPHLDDHTTKLLLSSLSKLLQSGNKPQDIYGV
QKLQQVSDKSNFLNRFPVPLSLEVIQLRLENNYYRSLEAVKHDINVMLSNAETYFLKQAE
FSKKIGRLSEWFEKKILSL
>Sgl00874 DUB/JAMM 31.8 2.2
MNVQPSTPAKPININTLTRKIDVDNRLSVGYYFRIADNLLKQAAVYREENNVVDLYVMLI
RFSSLVSETIPFHRDYQAYNPKERAHHKKKLMAVIDELETLKPEFQRLVDEHNKACTEMQ
QKQFHGREMTSYGSETSLVWPDVYDPSYESKQLQPANNKFQSSWKESYDFRAASTSTPIE
KKFSKLSFTVPLPNQETLSRHSFLGPNGLRRQWQGPSAEIKVSYPSHADLTPAEDLCLIQ
GIQNEARVQKDNSIGQDMEAVLSLDNGSWSRIQEDVPAEIIRQPVPPPVLAQIQPVSHPI
SPSRVADPRPGLAKPSEDGTQNPNSYQHLHIPVKMMEDFLRLAQQNTGRNLETCGVLAGS
LKNRVFHITTLIIPKQESTSDTCQTLNEEEIFEVQDSRSLFPLGWIHTHPTQTCFMSSVD
LHTHYSYQIMLPEAIAIVMAPTDSSSPHGIFHLSDPGGVSVIRNCQERGFHPHEEPSDGS
SLYEHCSHVYMNPKVRFDVVDLR
>Sgl00894 E3_adaptor/Cullin_RING/DCX/DWD 16.4 0.9
MQASKCTATIKYVTGLEFANFEVFITASGLSSMSLFMEDNERKIWDTVKGQLQTEFSDIV
SADETNLFAKQEKRGHLSIDYTCMKWVSFDRKKKRKLGTSLLVLGTGSGDVLALDVSAGQ
LKWKVNDCHPGGVSAISFASRGSCICTSGADGMVCELDPITGNLLRKFKASTKAVTSICV
SSVFCNGFNASWTHIYKGKPPLEQLTIPKSFFIRMEEIIVDSSTIRIFGIDAFVRRVLGL
VVVKKIVGVEFQLSSFRRVKVGWVLLERGRTDNVCGVVVLFKGDSEEEEMKNGVFKSHDG
KTIATAASQMKIFNSSDHKKIQKFTGHPGAVRCMIVSEDGKYVFSSAAGERYVAVWRVGG
SKMQSASCALAMEHPSVYLDCRYMNNSQADEAGLYVLAISEVGVCYFWYGKDTEELKKAK
PTRISLSAEDADSKNYKGVSAAIYAAKIQSAAEPATVSLFLAHGFLVKPSFEKVVVQYGE
DLQINVSRNGLLLPSSQPRKSKKQLELHAGATALDRANAEGALHPVPKVFDHDRIKQDQS
LKADYDQAVPIDTRADYNFPGVDATTCSMENRLKSLGIISDLKSTTPMKSSSLLKDIDLE
AMIPLKKMRAIIMSLSLVDALNILNVLVDKWLSRSCSGKYVLPWIYNILVHHGFQILSQE
PENATIYSLYKIAKSKGLASQSLLQISGRLQLVTAQIDKARQLKTQPSYMNNEMVESEDE
DEGVDEVHFGKEDESTTYNCGSTSKSTASPECVGGCEKEFGGMSTGKELLFVYGSGQWPV
GDILVS
>Sgl00906 E3_adaptor/Cullin_RING/DCX/DWD 85.8 5.9
MNCSISGEVPEEPVVSKKSGLLFEKRLIERHISDYGKCPVTGEPLTLDDVVAVKAGKIVK
PRPVQAASIPGMIGMFQNEWDSLMLSNFALEQQLHTARQELSHALYQHDAACRVIARIKK
ERDEARSLLAQIWAQNKKPMDMFEGEGNAAHATAISNGKRGAEEEDHGLVGKRARVGISN
DIIAELTDCNLELSQQRKKRTIPSTLAPIEDLERYTQISSYPLHKTNKPGILSVDIHFSK
DIVATGGIDTNAVLFDRSSGQIVSTLSGHSKKVTSIKIVPQDEGLVITGSADKTVRLWQG
SEDGNYDCRHVLKDHSAEVQAVTVHATNKYFVTASLDNSWCFYDLASGLCLSQVTDSSSS
EGYTSAAFHPDGLILGVGTTDAVVKIWDVKTQSNVAKFDGHTGPVTAMSFSENGYFLATA
AHDGVKLWDLRKLKNFRSFPSPDQDTPTNYVDFDHSGSYLTVASSDIRVYQVASVKSEWN
CLKTLPDLSGTGKATCAKFGPDAKYIAVGSLDRNLRIFGLPGDDGAQES
>Sgl00977 E3_activity/RING/RING 24 9.6
MGQQQSKDELLYQQVSYGNVEGIKTLHSEGVGLEYTDREGKTPLILACLNPALYDVAKTL
IELGANINAYRPGRNGGTPLHHAAKRGLENVVKLLLSHGANALLINDDCQTPLELARAKG
YSNVVRVIESHICLYSGWLRELYGPGFLELFAPQLLSRKVWVVVLPCGSRNLRKPFRLEL
AIYTNVQDAQPCTTIALWRATMEEPAFNQSNPSVTISEASIIRKHGKKRSCRPRRVSQTC
VKLVSLDENNKQQLQQFCSACKGIPQVMHPNFPFNHSTPFPPSTAPPAATEVPPVSKNTA
SPAADEDVELAMAIKASIQSAMEEGISVDHLRSPNDASSSSSTAAHSVSSNTQVDPPSKK
ASCSNQLVEEGETSVTSAITTNEPPTPMPAPSAPALTEEGFPEGPIHYPTIDSSMFATVE
TNHTNEDGSKRGESSSCVICFDAPVEGACVPCGHLAGCMSCLNEIKDKKWGCPVCRTNID
QVIKVFSV
>Sgl00979 E3_adaptor/Cullin_RING/DCX/DWD 88.7 13.8
MRIELEEYGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSSLRLLYSHIDKDHLIKL
LKQLLLSKVILPHGVATRNVPNAADVPTLLGAGSFSLLGYDENKGDNAVHVQSQPVHMRW
PHMRADQVRALRLREIGGGFARHNRAPSTRAACYTIAKPSTMVQKMQNVKKMRGHRNAVY
CAVFDRSGRFVITGSDDRLVKIWSMETAYCLASCRGHEGDITDLAVTSNNAMVASSSNDC
IIRTWRLPDGQPISVLRGHTGAVTAIAFSPRPSAVFQLLSSADDGTCRLWDARYSQFKPR
IYLPKPPDSVAGKSVTAPPIAGEQNYQIFCCAFNATGTVFVTGSSDNLARVWNACKSGTD
DSEQPIHEMDVLSGHENDVNYVQFSGCAVTSRCSASDTFKEENFPKFKNSWFGHDNIVTC
SRDGSAIIWIPRSRKSHGRAGRWMRAYHLKVPPPPMPPQPPRGGPRQRVPQTPRGVNMIV
WSLDNRFVLAAIMGKLMRLTFVY
>Sgl01036 E3_activity/RING/RING 34.5 8.0
MDNSPPSPSPPPPFQLPLLHSPKTSNFPVIAIVVIGILATAFLLISYYIFVIKCCLTWHR
VDIFNRFFSRVRDPSDEDGVSIATNNLLVNIGVEKKGLDEALIRSIPVIQFRKLADGRNL
NDETLEAGGGSYECAVCLSEFEEGERLRVIPNCCHAFHIDCIDVWLQSNANCPLCRSAIS
PSSILYNHHHHLVQLPQKEEDNNGCGRDNNDNDNDNDNDNDDDDYVVIEIEGNNLDEPTL
VTRESSAEKKKLRHVWSIGDELIDMRRKKDEEFQNIQPIRRSISMDLSSDREFCLEIQRF
SKSKEIEVSCSSGSSCNYSTKVRRSIFSFGYGRGSRCSVHLDP
>Sgl01101 E3_activity/RING/RING 36.5 8.6
MVRLKPYAGLSLFATIAVFYHAFHSRKQFYPAMVYLSTSKISLVILLNMGLVILCSLWQL
AKRLFLGRLREAEVERLNEQSWREVMEILFAITIFRQDFSVTFLAMVTTLLLIKSLHWLA
QKRVEFIETTPAVPTLSHVRIVSFMGFLLLLDSIFLYSSLKSLIETQQASVSIFFSFEYM
ILATTTVAMFMKYIFYVSDMLMEGQWEKKAVCTFYLELIRDLLHLSMYLCFFMVIFMNYG
VPLHLIRELYETFRNFKIRIADFIRYRKITSNMNDRFPDATPEELDSSDVTCIICREEMT
TAKKLRCGHLFHVHCLRSWLERQNTCPTCRALVLPPETGTTTAGGQPGVSQSGTHQPAST
STPGQGSNGGTESTLSGNQARLQAAAAAASIYERSIVYPSANTLMWSPGYAVLPQVYGAV
PGANNATSDEVQGLVGQFQHQQVISSGQMSYPYAQSPPFAVSSIQVPGTDMLREGNIQSS
MDSERNALEQRIQILQNQLNGLRKQQLDKGASSSYSASTVSNVQTAESISDATSHTNTQE
AN
>Sgl01113 E3_adaptor/Cullin_RING/DCX/DWD 93 15.9
MDPRNAFQEISLTRKNSKENLDRFIPNRSAMDFDYAHYMLTEGKKGKENPAASSPSKEAY
QKQLREVFNMNRPRILAFKNKPPTPVEFMPQEYAAVQQSKPVKPRRHIPQTSERTLDAPD
LMDDYYLNLLDWGSSNVLAIALGTTVYLWDASTGSTSELVTVDDDKGPVTSVNWAPDGRH
IAVGLNNAEVQLWDSTANRQLRTLKGGHRARVGSLAWNNHILTTGSMDGKIMNNDVRIRD
HVVETYRGHQQEVCGLKWSASGQQLASGGNDNILHIWDRSQASSNSATQWLHRLEDHTAA
VKALAWCPFQGNLLASGGGGGDRCIKFWNTHTGACLNSVDTGSQVCSLLWSKNERELLSS
HGFTQNQLTLWKYPSMVKMAELTGHTSRVLFMAQSPDGCTVASAAGDETLRFWNVFGTPE
VAKPAPKAAPEPFAHVNRIR
>Sgl01161 E3_adaptor/Cullin_RING/SCF/F-box 16.3 0.0
MKKRKFSQKNKSPKNDCCLPELPPELISEILARTPVKPLLKFRCVCKSWRSLIDSNDFVS
LHRKLYSTSFSDTRILVFQQRQRSYDYILTVRHSDTFKKVGDEVGKFPFTFWIFESCNGL
LLIEHEDTFKIWNPFIRKCLTIPLCPIDKPGCLLWYRLGFAASTNDYKVVVIDIQTGKIA
VYSVNDHCWQVKTNGINFDEGGFGVPLFHDCPTPIVFPDARAFYLVLCNNQNESKVIFSY
DYDTEKSKFIQLPDAVSVNDGNKLWFLFRFGESIAIFIMSSNNDYEYDIWVMEDDHEESK
ETWKLKASRKMNLKADKLFKSVITGYENSSNFMVLFNYIQQNDSFVMVKSSRFKFTDKLM
SYNLTSQEIKQLGKSLCGKISFDKYVESLALHRGVEGQTLVSFP
>Sgl01173 E3_adaptor/Cullin_RING/SCF/F-box 17.6 0.0
MKKRKFSQKNKSPKNDRCLPELPPELLSEILARTPVKPLLKFRCVCKSWRSLIDSNDFVS
LHRKLYSTSFSDTRILVFQQRQRSYDYILTVRHSDTFKKVGDEVGKFPLTFWIFESCNGL
LLIELEDTFKIWNPFIRKCLTIPLCPIDKPGCLLWYRLGFAASTNDYKVVVIDIQTGKIA
VYSVNDHCWQVKTNGINFDEGGFGVPLFHDCPTPIVFPDARAFYLVLCNNQHESKVIFSY
DYDTEKSKFIQLPDAVSVNDGNKLWFLFRFGESIAIFIMSSNNDYEYDIWVMEDDDEESK
ETWKLKASRKMNLKADKLFKSVITGYENSSNFMVLFNYIQQNDSFVMVK
>Sgl01201 E3_adaptor/Cullin_RING/DCX/DWD 59 5.2
MDNSSNKNLVTYDSPYPLYAMSFSHRSSDQLIAVGSFIEEFNNRVDVLTFDNETLSLNLS
PNLSFAHPYPPTKLMFQPPSSSSSSTSSLPILASSADCLRLYSFKNDSIELVSSLNNSKS
SEFCAPLTSFDWNDFAPQRIGTSSIDTTCTIWDIEKGVVETQLIAHDKEVYDIAWGEAGV
FASVSADGSVRIFDLRDKEHSTIVYESPEPDTPLLRLAWNKQDLSYMATTLMDSNKVVIL
DIRSPTMPVAELERHQLSVNAVAWAPQSGRHICSAGDDGQALIWELPAVVGPNGIDPLTV
YNAGSEINQLQWSSAQPEWIGVTFSNKLQLLRV
>Sgl01211 E3_adaptor/Cullin_RING/SCF/F-box 21.9 0.1
MGKLSTSHRPLSIPSSPTDACNNINNILVDSLLIEILQRLPCISVLQAKSVCKHWYLLLS
DSHFVQTFTRYHDHHTLPFTLVYEFHLWHRHLTNNLRHIIHIVSKHEVFKSRGFHLDFLP
CLQSWESHPIWLVGSYKDLLVCCHLKMSLLQGVYYVCNPLTKQWLGLPPAPGHHRLADTA
IGFITSEKLVCQNTFMLVQIPELDSCRCTGNCFKVNMFCSEVGEWRTYEVTSARSFARTW
QFRPDSVVFKNKFHWLVNSENIVVLDPSELTKGTCQVVDLPTELNPDIGICLGYCQDYLT
VCQITRGCFNCVLVVWKLRDYATGKWDLEGKINLKEMVLVKNIQLFEFRFSTMEVLAFHP
SDVGILYLRFDNQIVICNVGRRTLKVVSEYLQDSSFSVGTCGVFLLMHPCWPSQIPSLPN
WKSTWLPCHVVLRCKTVCKHWLSLISDPFFIRTFIHLQETVNQSSTFTLVHQFYYWHHHI
TESASRTVQAISEHPVVQSRGLLLDFVPCFQQFDPWPIRIVASNRDLVVCHDNKMFSHQS
MYYVCNLLTKQWRALPPIPSHHVEDDMATGLVTYGEDDLPVYKYKVVRILKIGSYSNHLI
AEIYCSDTGEWTESLLLCPQNIRRFWQFRTSAVTVNNALHWIINGNNGETIIVLDPFRGS
NGECRLIDPPLELKFEMAHVCLGMCRGKLRVSTIKGVHPNRMLKVWELQDYDNSKWLLKN
RICLKEMVFVGDCEFDLLEFSTNLVLSFHPVDENVVYLRCHNHIMRCNMKNGTLEVVSKC
LGDPTYVIRTLTVFPLLHPCWPSSVHCQSPKRASLERISG
>Sgl01223 E3_adaptor/Cullin_RING/DCX/DWD 39.9 18.9
MSTPFQVASLTNPPTFPNAVVWSDDNLIAVATADIVTILNPEHPQTPRGVITLTPSEPFQ
IGVIDRTDLLSGCLLPTCLSRDRQPCVRSLSWSPAGFTSHNGCLLAVCSAEGRVKVYRQP
YCEFQAEWIEAMDISVLLHEYYAKINYREPQAPSSAGFDDSSGQTRTKTYIAADKTNTMT
LRKHHKRKRDKDFNYLEEIDTSNAESLCVKAVAEPVYIQSSTMQEGSSVEVFKMDGGQNV
WIAGKLQRVEGSMALVHFCETDSSGEPKWRKMGFESDMHNQPKNTGVSTNDGDCGLPEIR
PSMELGRLSEQILLAELSEVDQFLKAGQLVEAWSRDRWVEGVFVSFSNGGLSVKFSGDAE
AVALNPTDVRLAPLWIAEKKSWKVTVVQCHVQDSPEVAVKKSDLGDLNYSSESDTELDIL
TRDGRNSSKRTTANSTKKKLTARQYSSRSSMLASLVVAWSSHLQLSATNSEKVLDCYCLL
AVGTKSGSISIWRFERPSYYSVERSDNSVSMSFIGVIQAHDTWVTALSWGFLTSDARTQV
LLATGCCDGSVRIWHAHVCDLKNVSETDQNPFSLVSEVTAGDNVLVSVVSLCVPIQSPQK
ILLAIGKGSGSFEVWTCDTKFKSSHNVGSYDAHVQAITGLVWAFDGRCLYSCSQDNSIHG
WMYHKGSLSEASVPPNNLGTRSFSDLPSVSDSCYGMALSPGNLALAVARRFDAGQLDNMY
QKRTQRAAVEFFWIGGQQVELPTTANLELDVEGYSSFSKEELGYWGSKLLWSLNQFECHN
KHLVIWDIVAAMLAFKPCAPWFIKHLAFRWVELLLKNHLDPSIKDIFSDMPKHLSKISSR
QLHLLNILCRRVIAPSGFEAVKVYAKAAALSKSCGEEEQQWMDIVLNSEKELRERLVGLS
LSTVLVCMSDEASKAESGLWNPVGVAQMVKWVILNKDHLSCQLSPLASKIEEFGTRLQSA
CDYNTEEQCSFCSAAISFESAEIASCEGVKISGQEPAQQHKLTRCAVSMKVCPLTAIWFC
MCCRRRASNLPPLQLFTMNKYPSDFLSFTKSLTANLLPNPLCPFCGISLQRLQPDFLLSL
SPV
>Sgl01249 ULD/UDP/UBQ/UBQ_PIM 97 0.3
MQIFVKTLTGKTITLEVESSDTIDNVKTKIQDKEGIPPDQQRLIFAGKQLEDGRTLADYN
IQKESTLHLVLRLRGGIIEPSLMALARKFNQDKMICRKCYARLHPRAVNCRKKKCGHSNQ
LRPKKKIK
>Sgl01250 ULD/UDP/UBQ/UBQ_PIM 97 0.3
MQIFVKTLTGKTITLEVESSDTIDNVKTKIQDKEGIPPDQQRLIFAGKQLEDGRTLADYN
IQKESTLHLVLRLRGGIIEPSLMALARKFNQDKMICRKCYARLHPRAVNCRKKKCGHSNQ
LRPKKKIK
>Sgl01276 E3_adaptor/Cullin_RING/SCF/F-box 19.8 0.0
MEGLPAELCLKVFCLLDYQNLSIAQQVCRKWNNLGADNVLWAKLFKARWGEDRAVLHNAD
CSKSWKAAYEVQDRCDRVGLEYKIIREGVDYYLIYHGEIQRHLGSRIQKRKTEDTKSFSR
QSGENGVAMQEGSLIGGTSYGILERILFFIGDLEVASSEAKRSRLM
>Sgl01284 E3_adaptor/Cullin_RING/DCX/DWD 85.2 12.4
MLKQTMDTCSDPGEFQFFDALEEIADSGVECPDSICSNSARGLSDSVSSSAQFDVWIQNL
ESVEARRSKFFNWLGVDVSRTSGDDSEEGCDSELGRDRIATVNDSVLKKTRFECEFSSIR
SEHHVSFCSVDDTEFSGNLSPKENLSGGMKDNVGDENREPGANLRVRTEDSVRSSSSSSS
EGYSPVKNTARSCSVGPTKKVKKWWLNRLRSFNCVMEGGQSPCNCDSSARRKIQRVKVHQ
SKTQSKELSALYYGQNIQAHKGAILTMKFSPDGRFLASAGEDKVVRVWQVVEDDRSNEID
IPDMDPSCVYFTMNNSSELKPVSNDKEKNGKLRRNSDSACVVIPPKVFRISGKPVHEFQG
HTSEVLDLSWSKNDCLLSASVDKTVRLWQVGYGRCLQVFPHNNYVTCVQFNPVDDNCFIS
GSIDGKVRIWEISQKKVVNWTETKDIVTAVCYRPDGQGGIIGSIAGSCRFYSISDNQLEL
DAQIYLHNKKKSSGKRITGFQFFPQDPNKVMISCADSQVRILQGVNVIGKYKGLRRTGAY
CTAFFTADGKHIVGASEDSNVYIWKCNDQDFSNSSSSIKKIKSSERFLSNASVALPWPGL
QNESNRNQWHDGAFNGLPHGSRPFFSPPHFSCRQDFFLELYYPKGSALWPEEKLVSSSSP
SLTSSMHKSEYKFLKTCQNRSDSDAWGMVIVTAGWDGRIRSFHNYGLPVPH
>Sgl01334 ULD/UDP/UBQ/UBQ_PIM 100.5 0.5
MSMASVALSPLRKESLNIPTFLSDRHDCLMNESILIYLTVGGSVLPIPVLESDSVASVKL
RIQNHKGFFVKNQKLVFDGRELARNDSCVRDYGVANGTVLHLVLRLSNIQAITVRTVCGK
ELEFHVERSRNVGYLKQQIAEKGKGFFDRKDQELICDGEELQDQCQIQKYCKNSDAVIHL
LVQKSAKVRTKPVEKDFEVLIVASDQNEKEVDEIVKDGCEWGIEPVHPFGPLNKQFCRDI
VFEQLIINPKIELPLVIKQLINSTFSGLDRGNRPVRSSEGCGGAYLMLDPAGEEYISVFK
PVDEEPMAVNNPQGLPESKDGEGLKKGTQVGKGALREVAAYILDHPRTGPRSPYHAEIGF
AGVPPTALVKSLHEGFYHPNGYTGSLKNLKIGSLQMYMKNSGSCEDIGPGDFPVEEVHKI
SVLDIRLANADRHAGNILVSRDDEGQIMLIPIDHGYCLPSKFEDCTFDWLYWRQARKPYS
SETIKYIESLDAEEDISLLKLHGWDIPSECARVFRISTLLLKKGVARGLTPFAIGSIMCR
ETLKKESVIEQIVQEAEEALLPESSETAFLETVSTVMDRWLDELSA
>Sgl01350 E3_activity/RING/PHD 34.3 20.3
MIIKRSLKSTMPTLKRCRVIQSSNTEDEDSNDRKKRKYNSYNNGGTNSSNNSSSSNYFPL
SLLGEVAAGVIPFNGFHRIFSANNNNDNADFRGFASSWCSDVSCSPAEEEDDDDDEEEEE
EGGRSGRMSKVKTRHVAEVAKESPRPPLVRTSRGRAQVLPSRFNDSILDDWKKEKTSKMN
NSNNFNGNNASSGECSDEYDDNGDYVSVRKNEKFGFKAMKGKVSGRCNVHRFEDETYGVS
TSTEEVGYENGFNDDNEEEEIGWKGRRSTNHDVRRYSSSRSTITSLRDRRHWLEFEKTGG
DWHGNDKRLMVNQRRNSREVGMDGFVPGDVVWVKSGKNDPLWPAIVINPASQAPRQILAF
RVPRAVCVMFFGYSKSREQRDYAWVKHEKIFSFADNVDRFQEQACLNGSSLSNFHKALEE
AFLAENGFLETLMQEINKTARSASCTNSVSRRAHEATGSHQGQEFHHYSQNGIKKAKDTT
LCAGCGAGLPLKMKKTGKASGSEGHFYCTSCAKSLRLKQYCGICKKIGNHSDSGKWVRCD
GCKIWVHAECDRISSNLFKDLGATDYYCPDCRVKFNFELSDSETQPRIKCNQNSDQVKLP
DKVNVICSDMEGIYFPSLHLVVCKCGYCGTEKQQLSEWERHTGSNVKNWKKSIRVKGSML
TLEQWMLQMAEFHAQAAASTKPPKKPTLKVRKQKLLSFLQEKYEPVYAKWTTERCAVCRW
VEDWDYNKIIICNRCQIAVHQECYGARNVRDLTSWVCRVCETPDIERECCLCPVKGGALK
PTDIDTLWVHVTCAWFRPEVSFASDEEMEPAMGILSIPSSAFVKVCIICKQIHGACTQCC
KCSTYYHAMCASRAGYRMELHCLEKSGKQITKMVSYCAFHRAPNPDTVLIVQTPSGVFSA
KNLLQSKKRTGSRLISSTRSVPEEASTQELSEADPDSAARCRIYIRPKNKNCKRKGEEAV
AHQVRRPCHHSLREMERVNAFRIVEEPKTFSTFRERLYHLQRTENDRVCFGRSGIHGWGL
FARRDIQEGEMVLEYRGEQVRRSIADLREARYRIEGKDCYLFKISEEVVVDATDKGNIAR
LINHSCMPNCYARIMSVGDDESRIVLIAKTTVPAGDELTYDYLFDPDEPDEFKVPCLCKA
PSCRKFMN
>Sgl01361 E3_adaptor/Cullin_RING/SCF/F-box 14.3 0.0
MIRSTKKHRKRKKQRLKKDNNELQNDNVLPLIIPSIPRDVELPEELIFSEILTRLPVNSL
TRFKSVSKRWNFLISTPHFIKSHIKCTNSNPFVPTNKTPDDSFGEKGLTVVKSGKFSDNG
VNTFLIGSCNGLVCFGRGSGFTSDYYFYVYNPLMGQFLHVFDPLGNFQGKLIYGFGYVSC
KDDYLMFVGGLQRRSCDNFVYVYSLKSDDWKKIGEFDVDGFSIFLGGRGVLVNETLHWDT
SQVRVSDSKYICGFDLVDETFKDVRMPRVFWDDDHNLDFKVCEMGGSLCVWVEDVYGEVE
MWSLRQYGVWDSWTKLFKIDMIFAVSNFYGCLENGKVLVQTEDGSLLLVDPDQNPPEFTS
LVKDLGDIEVLSYIRSPVSPFLHLHVPQMEDQAQVSYE
>Sgl01365 E3_adaptor/Cullin_RING/SCF/F-box 17.8 0.0
MKRSKHEENPFLGLSDKLLLEILYRLPVKSIGKCKLVCKSWHTLISDPNFAISHLDFSID
NNQPLTLISQKHDNLSRLEFRDPADITKGVTLARIKTQFLGGLFDNDRYNFIVGSSGGLI
CVYAKETGKRRRGYDSMSLWNPCTNEDVEIDLPVQGGKFYVHIESSWFGYYDDDYKVFMV
YTLHKRSDRLTDMYLYSLKEDEWTDVSEEGYDCISRAESVFLFGALHYLVERSKWIVIFD
LDEETFKKVPFSIQPDERPEHHQLSLGVIGEYECLCAMFVHRSEEWMCELWTLEEYDDWD
SWEKMYRIDLQEEIVRNCMQFLGFTYNGNLCIKQANGLVLVDTDCDPPSHIVARNPSFEK
VYKVMDYVESLVSPSSFE
>Sgl01366 E3_adaptor/Cullin_RING/SCF/F-box 20.6 0.0
MHLSKVMQTLINMISFKYEDDPFLGLPKELVLDILYRLHVKSLGRCKAVCRSWHTLISDP
EFSLSHLEYWNTNYQPLTLISQKYNILSTLELCDPTDITDGVTLAKLNHQFLDDGDVSDS
CYCFIVGSSDGLICIYVKQMEERRRGQDSMHLWNPCTTEEIEISLPVKWGSFYVYINSSW
FGCVPSCDDYKIFLVYSEWRPFQKSMYLYSLQSGRWRRVHVSDDDLLSISGANSVFFEEA
LHYLVSGKWIVIFDLVAETFKKVPFSIKPDQVSEYNDLLLGVIGEYDRLCAMFVHYLSDE
WVIELWTLEEYNNWNSWIKLYQIELQEDIISNCNQFLGFTYSGYLCMQHENGLVLIDPDD
DPPSHVVARNQSFAKAYKVMDYVESLVSPISIP
>Sgl01377 E3_activity/RING/RING 36.3 4.8
MDLNTLIIPFFLLVFSNFPCNKATSTNCSISKCGDSSGGNTPAIRFPFRIKSPGQEPSSC
GRSGFDVWCDERSKHTLIELPRSGNFKVKSIDYAAQEMWVNDPNKCLPKRLLTFNILDSS
PFGEVYHQDFSFFNCSNTLNNTSINNNDDDDTNFTHLKGLLIVGPIKCLSGSNHFVYAMP
TNGTTFTNHTSNLLSPLNCSLVAPLIKVPVQWPPSLHNDHTVLSLLADLHGDLRLSWYIP
ECRPCELNGQMCALETASNDSDVIICSDIPNEGIAGKLPLTTFIAVILVICAPSIICIVG
SIVIWIRHCYKHRRSNRNTQTGPVDSNGPTVNEELGQLAEVNIEFARHIVRMGLNEEANL
DRRPTVVISEMEEVGLGQGPNRENDNMCAICMGEYRRKDRIGTLPSCEHYFHANCINKWL
LSRGRFGKTCPICRAPVDSS
>Sgl01378 E3_activity/RING/RING 38.7 6.4
MILLDILSLMPMACILCLLSCLNTACHHEADSEILITLRPALSYCSKTMPKGDDDQQCSI
CLDDYEDGDMVEFLDCFHLFHAHCIDQWLPLSQTCPICRLQC
>Sgl01380 E3_activity/RING/RING 32.8 4.6
MDSAGNNPPTPSDDGSHTAVKWLGIVGAIAIGLILIRLCWIWCKWWHLQSRRRNNNNNNV
VIDLTYDNSPSPTNEPREVSGLNQLIIDSYPTVLIGKSGSAIKPHEATCSICLGDYVPGD
TIKIVPECIHRFHAECLDLWLINNITCPVCRIPPQNISSVV
>Sgl01383 E3_activity/RING/RING 35.4 5.9
MVMFDGRILPFAVVFSIMLLIYILCKMGWRKRGEAQLPVYVTEAQDQTQGQAQAQAQSQS
QVQEEPKKGLDQETIDSYPTVVIGKNMLMKLDDNMCSICLSEYRQNDVLKVLPECLHRFH
SDCLVEWLKLNATCPVCRTHPPRLNPTAS
>Sgl01385 E3_activity/RING/RING 33.1 17.3
MNRHNHQASYVFDIAPSPRRGGATTSSQSHSPPPAAVGTIGLDEVTIDSFPSMIIGESGR
MIKKDDNSCPICLSDYTPKEKLKMLPLCLHRNNVFTFSPKMHFLKNYTIFFLLCVLLPTS
TKCNENGSKLSDFCITQVCSYREPVTRYVQFPFLIRNESLPQSCGYPGFDLLCDGDYRLL
INLPNSGVFSVEEIDYVNQELWLNDPDDCLPKKLISLNGSNYVSKSPFNPVLEQDYWFYN
CTNDFFNSSDDEISVIQCLSGENYRVFATTMENIVKGKNSSFCGKIGPIKVPVRKRSFEM
YSSLELENDILLTWTKLRECGECYQKNGKCRFKRGSGLEVGCFNLPRRGLSRSAMFAIAV
AFVTPLVLVTCCFAYFILKAIWYRRRTNRARLPSFAELALAVTPQPERVIQGLDQTTIES
YPKVVLGESRRLPKPDDKSCAICLGEYLAKETIKTIPDCGHCFHDHCIDEWLLLNATCPL
CRNSPSKTPQSNA
>Sgl01386 E3_activity/RING/RING 32.3 8.8
MSDHCSIQVCKSDDPISRYVQFPFLIKNESMPSFCGYPGFDLFCNEDDKLTIKLPNLGAF
LVEEIDYVNQELRLFNDLDHCLQKKLLSQNGSIFVGKSQFLPIIEQDYWFFNCSNDFFNY
SNVEPIECISSTSYGVFATNVEKISESNSSMCQKIGPIKVPKGVNERNPSSILSGDFRLN
WYHPRECVTCHEKKGRCRFKGNSNLDVECFFPGRGLTRNAMVAIGLAFTAPLALITFIIV
YFVIKSVTNGQGRAGNRGEGVTLTPQPQNAGHGLGLDHDVIESYPKVVLGESRRLPKADD
VHCPICLGEYVAKESLRTIPDCGHCFHAECVDEWLHLNASCPICRKYPSKPPQIDDT
>Sgl01427 UBD/UBC-like/UBD_UBC 252.7 0.0
MASKRILKELKDLQKDPPTSCSAGPVGEDMFHWQATIMGPPDSPYAGGVFLVTIHFPPDY
PFKPPKVAFRTKVFHPNINSNGSICLDILKEQWSPALTISKVLLSICSLLTDPNPDDPLV
PEIAHMYKTDRAKYESTARSWTQKYAMG
>Sgl01445 E3_activity/RING/RING 36.4 4.8
MDLNTLIIPFFLLIISNFPCNKATSTNCSISKCGDSSAGNTPAIRFPFRIKSPGQEPSSC
GRSGFDVWCDERSKHTLIELPRSGNFKVKSIDYAAQEMWVNDPNKCLPKRLLTFNILDSS
PFGEVYHQDFSFFNCSNTLNNTNFTHLKGLLIVGPIKCLSGSHHFVYAMRTNGTTFTNHT
SNLLSPLNCSLVAPSIKVPVQWPPSLHNDTVLSLLADLHGDLRLSWYIPECRPCELNGQM
CALETASNDSDVIICSDIPNEGIAGKLPLTTFIAVILVICAPSIICIVGSIVIWIRHCYK
HRRSNRNTQTGPVDSNGPVNEELGQLAEVNIEFARHIVRMGLNEEANLDRRPTVVISEIE
EVGLGQGPNRENDNMCAICMGEYRRKDRIGTLPSCEHYFHANCINKWLLSRGRFGKTCPI
CRAPVDSS
>Sgl01446 E3_activity/RING/RING 33.9 8.6
MHPVDREVQATSNESAEENMAREKGNGDVQSSIVVGAANEGVPGSAEEDPMIHDMQEKPL
FIFSSTSEEKSQPAMVKKWKRIARVNGDTGDKINVGEKRRSIEELVTSDGDAQHGKRAKS
SSCDNADLSTPAVVVRRLRRWSNALAPGAVFVSETMISKATVEGLKERIGYSSAFGVSSV
GKSGGLCLFWQEDIVDFSLVSFSQNHICGDMRMGEEAWRFVGMYGWPDSSAKHKTWDLIC
DLTRNSPLPILLGGDFNEILSWDEKEGGVIGARREIDQFREALNVCELRDLGFEGQWWTW
ERGKTVETCVRERLDRFLASSAWCRLFPNARVEHLLRYRSDHAPIVIRLKYKKKRGRGRS
KSFKFETAWLLDDSCKAEVKASWDRASGCALEDKLLRVGGSLSSWSKEKFKDIDGKIEKA
ERDLRDCQSQGINQERCELQAKIEEQLNDLYEKQEALWHLRSRVQEIREGDRNTSYFHHK
ASQRRKRNMISGLYDKEGILQEDEECMEALIADYYTTIFSTSSPDASVTEEVLSLIPQCV
TAVQNSNLLQPVSSDEILQAIQLMHPCKAPGSDGFHAIFYQRFWHIIGHDTTEFVKEVIA
GKNIFPLLNKTNIALIPKVKNPKHVHEFRPISLCNVLYKIISKIMVLRLKTILPSFVSEN
QSAFVPGRLITDNALIALEIFHSMEKRSKGKKGTIALKLDMSKAYDRVEWGFLRKLLLTM
GFDGRWVNLIMNCVTSVSYSFILNGRVCGDISPSRGLRQGDPLSPYLFILVADAFSHMLR
AKTQNNLLHGAKASRNGPEISHLLFADDSLLFARANRRECEIIVEILNTYEVASGQKINY
EKSEVSFSGGVDEIRKQELTQFLGMRRVTKHDKYLGIPTIAGRSKKLIFNSILDRIWKKL
QGWKEKLLSRAGKEVLLKAVIQAIPTYLMGIYKFPCDVINRIKSAMSNFYWGQQGQQRKK
HWISWDKMCEPKCMGGMGFKDLSIFNDALLGRQAWRLIEYEDSLLARVMKAKYYPHSHFL
ESSLGGMGSYSWRSIWGSKALVKEGMMWRIGTGTRVSIWDDPWLVDEQGSTYMANAKHPF
RVTESCGCQGFDLYCDDEFGLLMEFPNAGNFTVDYIFQYSEREIQLSDPNNCLPQRLLAG
LNLSMTPFRLTRSVDFQLYNCSGVDYPMDSDYVEKIDCLSDADFDYSFLSIYSTIDLTWD
EHDECISCVLAKEKRSGGRDSYSKVAIVVFIVGITVPVSFVILFVICLCCRRGETPRNQS
AINTNADASTNTSATASSGLDQVTINSFPTVILGEHGGLTNKSEHDTCPICLSEYSPKDV
LKMLPHCLHRFHADCIDMWLKSQPTCPVCRTSPTLRFTDCV
>Sgl01479 E3_adaptor/Cullin_RING/DCX/DWD 53.7 7.6
MLKERMENMKYAEELVREFLVFRGFTSTLQAFETELSTDVGKDFQVDKILDLIFSKYVPK
FEAEKLVGLFSFFKHCFSSSETVLYATLSKLEVSVLRYYIVHAKRSGRNDKVREFFDMLG
DSLQQKGDDWTPWFAIPYLKSPGTDPQFCIYFSKEWLDALHLSLRNFLSQMFSSTRIPAL
LKISTEKNTVKHLRRDIKQLNLKLSQLQAVLEEREAQLHQLRRDDVILRREDDSARTSAF
SEDATPSNDSGENLVSTSRSGLETGFQSFGCSELPNRTARSANHTLRNSVNSPINSDQNG
AYNFSSEKEAVALGEEEFSEVKVQFQETFLGHTSPISRSRFSAAGDNIASASLDGTVRIW
TYDSSSPGSRNATIYCGAEILSLDWDCKSDRLLLIGTAEGGIKAWNVDAKRVVCDLSTGQ
TFRRVLDIKCSPVEPIFVSASASEGDETAYGSTMGHASLTVWNMKTWKAMSVLPLGEEPP
AITSLCFNHNGKILAVAAVDGMIHMFDMSAGLQITGWPAHDTPISSILFGHDETSIFTLG
SDGKVFEWSLQKQGQVVWSANCSRFCSLDTLKHCRHEMALDCTGKRLLVTSDLVRSPIYQ
VGSLANGSKTLPHSAAITTVDWHPTLPIYLTGSADNSVRVTSIS
>Sgl01486 E3_adaptor/Cullin_RING/SCF/F-box 21 0.0
MNGALERYQNLKLRQSLSLSYRYSVACKELGVILRLSYSKSPKPLQSLLFDDALFAFRLL
PKMQTQTDVSAANHLIQCAEAVLPKQKRSVATTEFKQSKVAYKRRAKTPKEDKDLIQLPQ
DVLVHLFSFLDLQSLACTSLVCWSWNAAANDNYLWQFHYNSHFGDLSTLKREDLQTEDRQ
HGASDGACKVAAYDWKDAYRRAYIGLPNRGYKYHRGYCGFCNSIVWLNSLKCPNKHAGQI
FGNKLLKPVSPAQIAIYILDDTSWSIISSDSDSESDDELINHKFWVWQ
>Sgl01535 E3_activity/RING/RING 23.4 12.8
MGILFSGRRNQNQNHHHHHHHHPPYYHHTPPPQPPPQPYYYHPTSTTTPPSAAIVEQTPL
PLPLPPPQPQPQPQTNSYVHLSPAYPSTQYQYQQQTPSVQSNCYYPGWSNNSNSYSNHGN
YYQNPIMGAPNFPYFPTNYGNGWHQMRPPLPQPQLQPPPYVEHQSAKVVKNDVNVHKDSI
KLVEDELYPEHFLVSFVFDAHFDGSITIYYFAKEEKETGTFTPAYSEAIKSVKVPFQKGA
GQRFHQASGTGVDFGFFDLESLGKPSEDDIFPLVIVAEVCSSEEGESSASSSPRAQVTQA
IIENTNEGSFHVKAIRQILWIDGVRYELRDLYGIGNSSSETFNDDEPGKECVICMTEPKN
TAVMPCRHLCMCSDCAQELRLQTNKCPICRQPITELIEIKINNTSQ
>Sgl01558 E3_adaptor/Cullin_RING/BCR/BTB 64.7 0.0
MGISRVCSESSKTSCSSCSTAITSSTTKMETVNGTHEFKIKGYSLSKGMGIGKYIASDTF
MVGGYLWAIYFYPDGKSPEDNSNYVSLFIALASDGTDVRALFELKLEDQSGRGRHKVHSH
FGRTLESGPYTLKYRGSMWGYKRFYKRTSLEQSDYLKDDCLLIRCIVGVVKTNTEGPKLY
KISVPPSDMGQQFGQLLETKKGTDVNFEVDGEFFDAHKLVLAARSPVFRAQLFGPMKEKS
TQCIKVEDMEAPVFKALLHFIYWDDLPDMQELAGLNSKGASTLMAQHLLAAADRYGLERL
KLLCETTLCEDVAINNVATTLALAEQHHCSHLKSVCLKFVASRENLRAVMQTEGFEYLKL
SCPSVISELLAFVAKVSEHSTAVVAYGNDPMLDCGDVNGRRVKPRIF
>Sgl01563 E3_adaptor/Cullin_RING/BCR/BTB 71 0.0
MEYNICFWKKVREDQFSILQGGWCRRKGGYYYNSGAGDGAGVGAAVVLQQWDGVGEGGCC
SEVGDGAGGGCCSSGMGWGKGCCCSVVGRGDGAGPAGMGGWSGFERGNNTDVSFEVDGEV
FSAHKLILAARSPVFRAQLFGPMKEKNMQCIKVEDIEAPVFKALLHFMYWDELPDMEEAT
GLNYKGVSTLMAQHMLAAADRYGLERLKLLCEVKLSKEVAINNVATTLALAQQHQCLQLK
AQCLNFVALHANLRAVMQTEGFEYLKESCPTVISELLGYVAKFSEHSKSFLTFGNETLDG
GDVNGRRVKQRLF
>Sgl01566 ULD/UDP/UBQ/UBQ_PIM 87.9 0.4
MRGVINERNSNSFVEANSSKSCVVQTWKIVTVQRFSTLLLFPLFLNLSRMKLTIKTLKGS
HFEIRVQPNDTVMAVKKNIEDVQGKDNYPCGQQLLIYNGKVLKDETTLSENSVSEDGFLV
VMLSKSKSLGGGGTSSTQHPTPNPAPSTTTAEPTPIPAPSTTTTEPTPSPAPSTTTAASP
PEAQMASKGESASNALSSSAPADTYGQAASTLVAGNTLEQTIQQIMDIGGGSWDRDTVIR
ALRAAYNNPERAIDYLYSGIPQTAEIVEPVPQFPANQANTVTESGTTPVAVSGAPNSAPL
NMFPQESMADAAAGGIGSLDFLRNNQQFQALRSMVQTNPQILQPMLQELGKQNPELLRLI
QDHHAEFLQLLNEPLDGSEGDIFDQPEQDMPHAISVTQEEQEAIERLEAMGFERALVIEA
FLACDRSEELAVNYLLEHADDHDD
>Sgl01571 E3_adaptor/Cullin_RING/DCX/DWD 74.8 2.4
MESFSAYLEVKIDKNTSVAAVDDINDRESDIANTQCHTPLLKGRSLLLELHPSPGFQVNS
VKWNHTNLVVASAGDDKKITLWRKNGQSLGTIPLLGSESGDNIEEAISSLNFSNKTSRYL
CSGGSGQVVRIWDLQRKRCIKWLKGHTGSISSAMYNCKDEHLASISINGDLIVHNLASGA
KAAELKDPHRQPASLATAGDDGSVHLWDTTGRSPKVSWLKQHSAPTAGLSFSPSNDKVIA
TVGLDKKLYTFDSNTKRSLSCISYEAPFSSLAFREDGLILAAGTSNGRVVFYDVRGKPQP
FTVLRAYGTSEAVTSLCWQRSNPMVVNEKNCTSEVALVGGAVEDSILMPDPLPSATSSSG
PQSTTFSGPRRSSSAVESNFAATMTNSNISSEETPHRNSLWAGGALPRLHAARNYNFKDD
MDVFSPLVDVQPITPAHDRLWNEPAGSRKDQPGDKQTSPLFPNRKFVTSEAITDVHPIFD
WKPGPASKQDDMQSMLSGSTPSASSSRSDDSSSITPPEAWGGERLSDKLAYHRQLGSLPS
RFSIPTSTSTTSTSLFTGLQDPSASQSTMNFPTSTSLISGNLRAKDIASGQDNSLGPLGH
VPFSALPNLGSKSAIGQANIEATTGPLSTMGLSRRYSTYEERIRTLSHNEGVSASVGSPK
TKKTGAETREDLHSSLLARSDITHASEPGLLSSINGAPNLQQGTPQADLQQGSSNFTLQL
FQHTLQETLSSFQKSIHEDVRNLHIEILRQFHMQETEVSGFMTTVQDKLTSLTEEIQDLK
KENERLRQLL
>Sgl01593 E3_activity/HECT 366.6 0.1
MFFSGDPSARKRVDLGGRSSKESDRQKVVEQTRLERNRRMFQRKQNSAAIKIQKCYRGWK
AVEAERHKVREQFFATYGKRCQNVSRDCFGPDSRFLGELLFFLNPRNADDLTALAETGRL
LQHFAQDTGGLVTLFAGMDYSTNHCLVSYRVKQLTYACIRAVHAKRSQLKKQSFLSESNS
HILSVFLEATVLLIDPKLPWACGIISYLLQRNAFTLLREITFAVKESLNPQNMIKVSSLE
QVLILIMSHVGEKPCVCQNADQRWIFSSQILTIPFLWQMFPCLKEVFARQQLFKYYVHQM
SLSVRSHINSLAKDVSAEYPSYACLLGNILEAATLTISETDSSFEMAVDFVSVATFLLDM
LPPLKSVSKETNESSSMEDDEMIDAEEYYGNALCENLESQISNAIDPRFLLQLIKVLLGG
VPPFTSGNCPDDKEVVAIGAACAFLHVTFNTLPLERIMTILAYRTSLVPVLWSFMKRCHE
TQKWSLVAEQSSYLPEGVPGWLLPLAVFCPVYKHMLMIVDNEEFYEKEKPLALKDIRYLI
VILRQALWELLWLNPVAPSNFVKSKSKSLAYKKQPLEFLQYRVSIVVAELLTQLQDWNNR
RQFAPSSDFHADGVNEFFISQAMQENTRAREIVKQAPFLVPFTSRVKIFASLLAEARKVD
NARAVFGRNRLKIRRDQILEDAFSQLSTLSEDDLRERIRVTFINELGVEEAGVDGGGIFK
DFMENVTRAAFDIQYGLFKETADHLLYPNPGSGLVHEQHLQFFRFLGTILAKAMFEGILV
DIPFATFFLSKLKQKHNYLNDLPSLDPELYRHLIFLKHYQGDVSDLELYFVIVNNEYGEQ
TEEELLPGGKNTRVTNDNVIPFIHLIANHRLNYQIRQQSSHFLRGFQQLIQKEWIDMFNE
HELQILISGSLDGLDIDDLRSHTQYSGGYHAEHYVIEMFWEVLKGFTQDNQRKFLKFVTG
CSRGPLLGFKSLEPQFCIQRAAGDASEESLDRLPTSATCMNLLKLPPYRSKEQLERKLLY
AISSEAGFDLS
>Sgl01617 E3_adaptor/Cullin_RING/DCX/DWD 43.3 15.0
MEGEFCIDCLKHRIQSDYSDKLFFSYAISDSVLPFSSKAVVQMPNSSGEVSEFVLVYLPQ
QQDECITKYVDDHILNDDECIENHGEIHQSTNEEVCDNSFSSPSPSQIQVSPLLSSKMKT
EVCDLYCDNSSFYYSGRLSCLRAITALAPCAFVGNCTFDAFGKIASSFSSGWLEDDTLCS
LSVMIEGKAICHSSRNFLSLLGIPSFCGNQVPGCLRHPNLVPVLGMLKVPGYNSVVFPKA
PYTLENVLHYSPAALNSEWHTRFLIYQLLSALSYIHNLGMGHGNVRPSMVMFPSSSWAWL
SICERPYMQYISADKDEDPLVSPVTRKSCSSHDCLSKSLYADLNLSSSVDWPTDFYRWWR
GELSNFEYLLVLNKLAGRRWGDHTFHTVMPWVIDFSVKPDENNDLGWRELSKSKWRLAKG
DEQLDFTYTTSEIPHHVSDECLSELAVCSYKARRLPLSVLRMAVRSVYEPNEYPSTMQRL
YQWTPDECIPEFYCDYQVFLSLHSGMNDLAVPSWARSPQEFIELHRNALESERVSREIHN
WIDIIFGYKMSGQSAVAAKNVMLPSSQPTKPRPIGRRQLFTQPHPVRWGNTKRIRDLATV
GETNSLLHENIVDVETPSFQGTDYIKGIEDIATFCQHSRHLSPMYSENIAKSSSDDMETM
ESSSKKRECHATETTENRISFGMLPVIDSNSLLEFLEEDEGSEGYQELLLWAQQSSCQRK
LSTCVAKDIFSLGCIIAELYLRKPLFDSVSLSTYMDSGALPGMLGELPPHVKIVVEACIQ
KDWRRRPSAKSLLESPYFPTTVKSTYLFVAPLQLLAKDASRLRYAANFANKGAFRVMGTF
AAEICTTFCLPLLENSLSDVEADWAYILFKEFLKCLKPEAVKRLVLPSIQKILQATGYSH
LKVSLLQDSFVREVWNHVGKQIYLEILHPLVISNLLNSPHKSSASAASVLLIGSIEELGI
PIAIQQTILPLIYCFGKGLCADGTDALVRIGAVMGENFIVSQVLPLLKNVVHSCIDTSST
NKPEPLQSWNSLALVDCLFVLDGLIAFLQTEVVVKELLEGQRCLFVMILTQSNLELPVLQ
AAAATLMTVCKQIGPDLTTVHIVPQLKELFNELAFSQELSGVPTSLGKSYKVSKLRPDKE
AQIESRMDLVSLLYPSLANILGIERLRQCFATWLLLEKYLLRCHNWKWECTGDSSRSSSG
NFNGKQAINKESVKSKYNPTNMLMNGVGWAVPQSQGSKGGNDMVIHRRFYEFRQNSVEGN
SEASRVGKCDPWFWFPTPASNWEGPDFLARSGTSKDELPWKIKASVVHSVRAHHGALRSL
AVDQDECTVFTAGVGPGFKGMVQRWDLSTVDCVSGYYGHDEVVNDICILSSSGRVASCDG
TIHVWNSQTGKAISIIGESSANLVQPSISSSSSSSTRINNDQANLLNSYPHSGGIFTSID
GSLYTCMHFLESVEKLVVGTGNGSLRFIDPAFGEKLHMWSSESKEYGFPSLVSAVCSCGS
DKMESSSSHSWIAVGQGSGNCKLLDTRSGNVIASWRAHDGYVTKLAAPDDHILVSSSLDK
TLRIWDLRKSFPPQPTVYKGHTDSILDFSIWAQDVISISKNKIGLSSLAGALDEYGQHNI
VRQALHTEDRGARNISVLSSISILPFSRLFLVGTEDGQLKICC
>Sgl01633 ULD/UDP/UBQ/UBQ_PIM 57.3 0.5
MQIFVKTLTGTTITLDLELRNTIKDLKSKIGEHEGVPKDEQRLLFGDKELVDKYENEEKT
EDHTLTHYNINKGSTIHLTSRLGGGGVYAYSLLVSRNLAVYPYQSRLNKQVCRKCYARLP
PRATNCRKKKCGHSNQLRPKRAWYFRRMFQK
>Sgl01657 E3_adaptor/Cullin_RING/SCF/F-box 20.8 0.0
MMNSLNSRNGVFPDEIILQILARLPIKSLFRLRSVCKYWYELLSDKYFVSLYNEMSVKSS
MILVEITEVSESKSRLICVDYLRGVSEFPLDFLKDRVRVRASCNGLLCCSSIPDKGVFYV
CNPMTREFKTLPKSRERPVTRFYPDGEATLVGIACDVADSARFSVVLAGYHRPFGYSPTK
TFICMVYNSEMNKWRKFVSLQEEHFTQMNRNQVVFVNGMLHWLTVSYSCILVLDLEIDVW
RKIYLPVEMSYGTGNRMYLLESDGCLSVVQISDAWMDIWVMENYEKQEWRMVDRVSLRCI
RGLAPGIFPISQAGECVFLATLKQVLVYNRSTSVWKEMYSVKSNSTLPLWFSAYAFRSTL
FHFTK
>Sgl01666 E3_adaptor/Cullin_RING/SCF/F-box 18.6 0.0
MATLPTEQITEILSRLPVKSLIKFTCVCKSWYSLIKSPKFIKLHLNQTLISNSNRFLLIS
YSSKQSSNNNLCRNHLVLSEFDTNPNDNQLKYSEIHHPLNHREITLLGDCNGVVCITDKP
KNNVFLYNPMTKSCLKLPRNRTSKNNPNNKQSLVFGFGYDAETDDYKVLRLLQDSHFNNV
NYKEAELYSMRNNSWKYVEKIPYFLLFLDRHGVYLNGAIHFVVVTAELQMHRKFIASFDF
KTESYSLMECPDYGDKLGASLDMGEISGCLCLMVMDRIMLPFDEIGFRMDSAELWVMKEY
GKSESWVRVFSIPATATSVGMYLHARPLAYSKDGKKVLIEYDYLGIGWLDLDTQKFVMFE
GVPKPPIFSRVFQGSLVSVGDDKLKFEEAAAIPRKNTKKKNVDNFLSSGFKLKL
>Sgl01679 E3_adaptor/Cullin_RING/SCF/F-box 20.8 0.0
MMNSLNSRNGVFPDEIILQILARLPIKSLFRLRSVCKYWYELLSDKYFVSLYNEMSVKSS
MILVEITEVSESKSRLICVDYLRGVSEFPLDFLKDRVRVRASCNGLLCCSSIPDKGVFYV
CNPMTREFKTLPKSRERPVTRFYPDGEATLVGIACDVADSARFSVVLAGYHRPFGYSPTK
TFICMVYNSEMNKWRKFVSLQEEHFTQMNRNQVVFVNGMLHWLTVSYSCILVLDLEIDVW
RKIYLPVEMSYGTGNRMYLLESDGCLSVVQISDAWMDIWVMENYEKQEWRMVDRVSLRCI
RGLAPGIFPISQAGECVFLATLKQVLVYNRSTSVWKEMYSVKSNSTLPLWFSAYAFRSTL
FHFTK
>Sgl01701 E3_adaptor/Cullin_RING/SCF/F-box 11.9 0.0
MKQKRIKSPPKSLPIDVIHDEILTRLPAKSLLRCRCVSKLWCSLISTPSFMSTHFKKCQN
NQEKTRLLVLEPPDMCDSKQICAIRSGEKFRKMSKIGLDVTWFEQYQAVSYVNGLLCMKK
YVKETQLSEVFLWNPSIRKALELPFPRFSKDTKVRYDMDCALGYDHINNDYKVVASVYVG
NELRIPKHIEVFTLSTFSWESASIGNGPCMWIKDGPKVFLNGIIYWGAIHVLKPTPKGRF
SQFMSFDVTNDAFEYIDLPDNGHVHEWEYERFPIILDQSVGLMKVFESYSQIWVMEETKE
NKAQSWIKRFTINLQLLEKCIYFKMDGELLFEGEKGGVNSYNIKTQETKVLAKSYKLSPV
FTSVYMESLALVEEVHERASYTFPPEKTIKSDCDLGSSFLYLFPNAISSFY
>Sgl01713 E3_activity/RBR 150.4 29.7
MESDEDPLDAYDGDSAEDYYYSGGDSDMGDSIDGVGDYDDDDDDDDGAFAYASDDESFLQ
HEKNYTVLKVGDIQQREEESISHVSSVLSISRESASILLCHYKWNVSQLHDAWFADEERV
RRTVGLLSTPVVFSNAKELTCGICFDSYPRDQIHSAVCGHPYCTTCWKGYITTSINDGPG
CLLLRCPDPTCCAVVGQDMILHLVSDEDKEKFYRYLVRSYVEDKKKTKWCPAPDCGNAVE
FEVGSCVYDVKCLCSHAFCWNCSEEAHRPVDCPTVNKWILKNSAESENMNWILANSKPCP
KCKRPIEKNHGCMHMTCTPPCKFEFCWLCLGAWTDHGERTGGFYACNRYEAGKQEGLYDE
DEKRREMAKNSLERYTHYYERWASNQTSRLKAVTDLHQMQTIHLEKLSDKLKEPESQLKF
IIEAWQQIIECRRVLKWTYAYGYYLPDHETAKRQLFEYLQGDAEANLERLHQCAEKELLV
FLGNSDSDTDIQSDFKIFRPKLAGLTRVTRSYFENLVRALENGLSDVDSQAASSMSVTST
NVGAKGKGGKVKSSTSRTGRSVARNNIDDVNHWNCERCTFANPDSSASCQMCHNRR
>Sgl01754 E3_adaptor/Cullin_RING/SCF/F-box 17.6 0.1
MMKNEELNLIRSLSEEIPSSIMVDILLRLPIKACLNCKLVCKDWYQIIISSEFANLHSSQ
CSFSTILLYGKFNSKKKDFLMFDLDKSSKVDEMGNLSVDANALIRFKSKLNTSHDKLYVV
NECNGVVCLKSWEQWSPYIICNLLTGQQVIVEQLPNSCCSVEVYGLGCCPVSHQYKVLRI
LKLKGTDRCVTEIQTLGTNEWRTVGDAPQFQLRRSGAFLHGSLHRYSYRDNCIWSFQFGN
EQFSHVPIPDDMKREPYTEVSVFNSRLCFSSISESCRQCEIWLMMDYGVKDSWVKQFVFQ
IESFAHRMPLLQLGTGEVLVSYSNSARLGACDTESGKYKTVRIPGVSFSQVIMCNAKFSK
FRNYPHYSS
>Sgl01755 E3_adaptor/Cullin_RING/SCF/F-box 17.2 0.1
MKSMKTVKTNRSPVEEIPPEVMLDILSRLVTKTCLNCKLVCKNWSAKKKRTDFLLIDLDK
SCKVDEDGSLIVSNNDAVIRFKSKLNDLSHSNLSVVNECDGVICLACHRRWKSYVICNLL
TGEQVVLKQRWRKFCVGTYIYGIGCCPVSRQYKVVRILCMSTTTSENNKSVKYKVVAEIQ
TVGTGEWRRVIDVPNKGSLMYCDYSPKAFLHGSLHVYYSPDKPNYIWSFNFETERFSRLP
TPVQIRGWRAKQSSFVSVFDSCLCFNTYDDESNQCVIWLMKKYGDKASWIRQFVIQPLDH
WLNLPLLRMSTGEIPVSGWRTLQSYLEAPSRGKNVKFHGGFPFRSLTPFNPKFSKINTAT
PVEVKLKRRCTLRTQ
>Sgl01758 E3_adaptor/Cullin_RING/SCF/F-box 19.8 0.0
MKSMKTVKTNRPPVEEIPPEIMLDILSRLVTKTCLNCKLVCKDWYRMIISQEFADLRSST
RSCSTTILVHSQFQVGKKKSTDFFLIDLDKSCKVDEDGSPIDSNNDAVIRFKSKLNLPHR
NLSVVNECDGLICLACRRRWKPYVICNLLTGEQVVVKQQWRESCVGTYIYGMGCCPVSRQ
YKVVRVLCMRTTTSDKSTKYKFVGEIQTLGTGEWRMVIGDAPRCQFLQPKAFLHGSLHVY
SIEENCIWSFNFETEQFSKLPTPVEIHGRRAKNSSFVSVFDSCLCFTSYDYENKRVIWLM
KKFGDKASWTRQFLIQPLDHWFNLPLLRMSTGEILVSGWRTLQSYLSSRGKNVNFHGRFP
FRSLTHFNPKFSKINAAIPVEVKLKRRCTLRRYVLNELH
>Sgl01835 E3_activity/RING/RING 20.1 8.8
MVNDFMVCVDRIIASACLQSVETNSGFHHQIVDDDDSNKKNQKFKLETLNTTISSSSSSS
CLLQKECRICQEEDDDNSLESPCACNGTLKFAHRKCIQKWCNKKGDITCEICNQVFTPNY
TLPPKPASDVMAVDISQAWGHHFTFRDHQLLALAAAERQLLESEYDDYAAANAGNVTYLR
SIAIILMFVLLIHQVLMITRDFGLMQGYLTVFHVEVSLLQLAGFLLPCYALLRSWYILYT
RRRRQG
>Sgl01840 ULD/UDP/UBQ/UBQ_Other 31.5 0.2
MDSEAASSSRNDQESDDDEEYEEAGGGNGLLGFMFGNVDNSGELEVDYLDEDAKEHLDAL
ADKLGPSLTVMDFSGKSRHTSVAASAAEEDYDEKADDAVDYEDIDEQYEGPEIETATEED
HLLPRREYISADVSVATLEHRPSCFDDENYDEDVDDEKELDDVVHESEIKSAAETDFALK
PQDADQIEPVDNSFGTQVIASPVKLGDDDMNFSQEIHSESLLAPVPVQSEVAAVFPELQK
QEEPIVSHNTADAKSLRPLPILCVEDGEAILRFSEIFGVNAPLKKAGRRGHRYSVPKDKY
ISLDASHMVEEDEESILRGSCNVFSNRNLLLHETQDRDEMSMDDDSKLDLAEGMHSVHDK
KKDFCLSAEPMRKDSAFDLSDEWKSCMSMEFYSLDQQDWEEKIMWGNSPSVSENSVESCD
LSGPDSEHVAHEEKELISRPQTLLSDSKTEQCEKDKCCHNGFVNFSVESFGTRDSATAAF
SESMFHPQLLRLESRLENDSSSLSDRRKENESEEHEQLDFMKRFKQLTLQNKELVEGSWV
ENIIWEAEKPIVKPKLIYDLQDEQMVFELLDNKDYEHLQVHAGAMITTRSGKAGAEAFEG
PSHGTFSGGRFNISSDKYYSNRKTSPQLKSLSKKRTAHSVKVLHSIPALKLQTIKLRLCN
KDITNFHRPKATWYPHDSRLAVKELEKLSMQGPMKVILKSLGGKGCKINVDGEETINSLK
VKASKKLDFRLTEAVKVFNMGNELDDQRTLVDQNVRPNSLLHLVRTKIHMLPIAQKLPSE
SKSLRPPGAFKKKSDLSVKDGHVFLMEYCEERPLLIGNVGMGARLCTYYQKTSSDDQNGE
MLRNAKNGLGTVLSLDPADKSPFLGDIKPGCNQSCLETNMYRAPVFPHKVASTDYLLVRS
AKGKLSIRRIDKIHAVGQQEPHVEVMSPGAKGLQTYMINRLLVYMYREFRAAEKRGMLPW
IRVDELSAHFPNIAEHFLRKKVKHCADVQRGPNGLSYYAMRRNFHIPPEEELRRMVTPET
VCTYESMLAGIYRLKRLGITRLAHLTGPTQLAALSSAMNQLPDEAIALAAASHIERELQI
TPWNLTSNFVACTSQDRENIERLEISGVGDPSGRGLGFSYVRVASKPPVSNALVKKKPAV
PRGTTVTGTDADLRRLSMEAAREVLLKFNVPDEQIAKLIRWHRIAMIRKLSSEQAASGVK
VDPTTISKYARGQRMSFLQLQQQAREKCQEIWDRQILSLSAVDADENESDTEANSDLDSF
AGDLENLLDAEEGEEADEGNLEMKNYKSDGVKGLKMRRHASQARLEEEIEDEAAEAAELC
RILMDDDEAEWKKKKKPKPSGEARGPSRGPQLSFGFEKTEQVKKPNTMVKYADGHVDVPL
IGKQNADIDEVEKLHTKKLMSTKGKTAKKIDALPVDLLNKKVKIMTEGIYKGYKEKKSAR
ETFVCGACGQVCLLVSS
>Sgl01855 ULD/UDP/UBQ/UBQ_PIM 53.2 0.2
MQVIIVTNNFTNFSLEITPREPVLVIKQKIANILGIPVFFQTLSVLGIELINGLDMDDYP
IINEGTRIDLIVSSTDEEMIMPPMDDYYTEHTSSHTKIPVTIKFSTREINIEVDMITETV
RSLKEKIHIIDGTPIKRMLLYTSGVEMEDDYRLLSEYAIHEYSEIAVFLRSMNRLKAEPP
CRKLKMVVQTSKSLLNAASIPLEMKDSCTLNEVRQFMLSRRILPMDDYIFIHKQRIMRDN
CTLRWHGVENEDYLYVFKGTISKNGC
>Sgl01858 ULD/UDP/UBQ/UBQ_Other 57.1 0.0
MQVIIVTNNFTNFSLEITPREPVLVIKQKIANILGILVFFQTLSVLGIELINGLDMDDYP
IINEGTRIDLIVSSTDEEMIMPPMDDYYTEHTSSHTKIPVTIKFSTRKINIEVDMITETV
RSLKEKIHIIDGTPIKRMLLYTSGVEMEDDYRLLSEYAIHEYSEIAVFLRSMNRLKAEPP
CRKLKMVVQTSKSLLNAASIPLEMKDSCTLNEVRQFMLSRRILPMDDYIFIHKQRIMRDN
CTLRWHGVENGDYLYVFKGTISKNGC
>Sgl01876 E3_adaptor/Cullin_RING/BCR/BTB 24.7 0.0
MASALCDRSWTPLPSSHMNSSFGLSKTEESPVEILPVSEIPISSSSAQSIIPAPPPLPKS
GFLKRRYKEKSSECFCISKEARDLWDKLFEKGYEADVYLITENKENVPAHSCVLSVASPV
LGKYLQDSKIVNGLRYVKIPGVPHGAVCTFIRFLYSSCYEEDDMKKFALHLLVLSHSYVV
PLLKRVCVQYLEKSWLNTENVIDVLQLARKCDAPRLSFMCIRMVVKNFKLIASTEGWKVM
RRVNPALEQELLESVVEADSRTQEKQQKIEEKKVYLQLHKAIEALSHICKDGCSTIGPRD
KMLKGSEVSCSFPACKGVEMLFRHFFSCKTRVPGGCVQCKRMWQLLELHSRMCDVPDSCN
VPLCRHFKEKVRQQSKKDEAKWKLLVRKVMAAKNLSKPFATSLSSFS
>Sgl01885 ULD/UDP/UBQ/UBQ_PIM 177.8 1.9
MQIFVKTLTGKTITLDVESSDTIDNVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLADYN
IQKESTLHLVLRLRGGTMIKVKTLTGKEIEIDIEPNDTIDRIKERVEEKEGIPPVQQRLI
YAGKQLADDKTAKDYNIEGGSVLHLVLALRGGASSCFSA
>Sgl01894 E3_activity/RING/U-box 195 4.6
MSESKGTVQGQLIVGVALTGSRKSKFLLKWALEKFLPEGNVTFKLLHVYPKITIVPTPMG
TWMPVAQVREEVVTGYRQETEWKKQRKLIPYLKKLKAQKIKADLVLLESDDVPMAISLET
AKQSIRHLVIGVTTTSIFSMKNLSLARGGDLSHNISENVPSFCSVYLVGSDGKLQQLRPA
DAEPNVIAMDDRSNLSSTSTDSSSSPSSLTIGRLLKRTPSSPKYRGSANASDSSHPPSKS
KEPESLPTNGTGPKISARETIELKHFAFKETNFNSGNASVRSHSSSSGDSESWISDRTSP
GGSFVAAHSNIPSPIGTPPSRYFVSTAPTSSFVGTPANYAGTPSTGSFMATPPALSPMGT
PPTSSYMGTPPAHSRAGTPKGGSYVGTPPKVSFLGLSSGSDTGDSQSQITELDKLRIELR
HIEKMYELSQSSSIDERLDKISKERPEEALKLKEEKGKELARVETNKSNESQGEVTYTGE
GAERNKPRNKADTKDAQEAEEIKNKLKNLFASTAVQYQKFTWEEIMAATSSLSDEFKIGM
GAFGTVYKCKLHYTTVAVKVLHSKDSVTNKQFVQELEILSTIRHPHLLLLLGAVPEESCL
VYEYMDHGSLDDRLFKKNGKPPLPWYDRFRICYEVAGALAFLHSTTPRPIIHRDLKPANI
LLDHNLVSKIGDAGLGTMINVGPTNASLKTIYKETSPVGTLCYIDPEYQRTGRVSTKSDI
YALGVVILQLLTAKPAVGIAYVVEDAIDEGTLTEILDPEAGEWPDKETLELALLGLQCAE
LRGRDRPDLRSKMLPILERLNELADCARESISSSYTTTPPHYFCPILKDVMEDPYVAADG
YTYERRAIEQWLNENDTSPITNEPLPHKFIMPNTTLLEAIKQELLIVRCQEMAESTATDQ
SQLVVGVALTGSRKSKNVLKWALEKFLPEGNVTFKLIHVYPKITIVPAPMGTWLPAAQVR
EEVVNGYRKDIRWQKQKKLIPHQNNLNAQKIKTESILLESDDIPMALSLEITRQSIRHLV
IGLTSTSIFSMKHLSLTRGSDISQVISEKAPSFCSVYVIGSDAKLQQLRPADSEPDVITM
DDTNPLLKSKPPSPRCKGSVTASETFLFTSKPKQPESLPRNAVGPKIEIARETLELQHYV
FKEPTLILPVFGVKILAVETLNHGFLIEHLLEFHLLQPILMALHLYALPLKGTPSTRSFT
ATPPAGSYASTPAISCAGTSKGGSYVGTPPLLSHLGTSKGGSYVGTPGVSCTRIPAGGSY
VGTPPAVSYAGMPTGGSYVGTPPLISRAETPTGGSYVGTPTPDSFLGIPSGSETGSSHCQ
KTELERLRMELNHIEKMYALSQNHSIDERFLIPLDQLNEISKERLKEAKKLKEEKGKEIA
RMQKNKSTASQIGVKHIGGSTEKIKHKNKVDIKASLDADENKNRLKNLLANPAIQFQKFS
WNEIMEATSSLSDEFKIGLGAFGTVYKCKFHYTTVAIKVLHCKNSVTNKQFVQELEILST
IRHPHLLLLLGAVPEESCLVYEYMDHGSLDDRLFKKNGKPPLPWYDRFRICYEVAGALAF
LHNTTPRPIIHRDLKPANILLDHNLVSKIGDAGLGTMINIDPTDQSVQTIYKDTSPVGTL
CYIDPEYQRTGRVSTKSDIYALGIVILQLLTAKTAVGIAYMVEDAIDEGTFAEILDTEAG
EWPEKETLELALLGLQCAELRGKDRPDLRDKVLPILERFNEVATSARESASSAHTAAPTH
YFCPILKDMMEDPYVAADGYTYERRAIEQWLTENDISPTTNQPLSHKFVVPNNSLLEAIK
QWNTLLAIHRLSMSNTSNANQGRLVIGIALTGSRKAKHIIRWALDKFLPEGNVTFKIMNV
YPKIVVAPTGPTPMGTWLPVIRDPVEIENRYRQEIELKRQKKLLPYLHFVYEAQQIQADI
VLLESDDIAMAISDEITKQSIRHLVIGGPSAGGIFSMKNYAQPTGDELGPIIAKSAPSFC
SVYIIVDGKLQQLRPADSEQNVITLTIDDTNNSPNSSTDSASGSSSLTIGRLLKSKTSEP
QYGGSANTSDLSHSNSQPKQPESHSKNRPKFLTREVVELKHYDFKDSNISNGTGGSGSWA
SDRTSPTGSYIGNHSDARSSMGTTPPSSYVGIPPTQFRNTPPAVSPVGTPPTGSYVNTPK
AIYHSGTPPGGSYVNTPPKAPHERTPRSVTFQGVSSGSETGASSNQISEIEKLRIELQHI
AKLYEQSQNSSIDERLNGISKERLEEAIKDKELARKEKNKYKAGKGEAVDTRGKSEQSKT
KNSKDAQEAEESRNRLKALFASPAVQYQKFTWDEIMEATSSLSDKYKIGMGAFGTVYKCK
LHHTTVAVKVLHSKDSVTNKQFVQELEILSTIRHPHLLLLLGAVPEESCLVYEYMDHGSL
DDMLFQKNGKPPLPWYDRFRICYEVAGALAFLHSTTPRPIIHRDLKPANILLDHNLVSKI
GDAGLGTMINVEPTSASLKTIYKETSPVGTLCYIDPEYQRTGRVSTKSDIYALGVVILQL
LAGKHAVGIAYLIEDAMDEGNLTEILDPLAGEWPKKETFELAVFGLQCAELRGRDRPDLR
DKILPTLERLKEMADSARESASSAQAATPPHFLCPILKEMMEDPYVAADGYTYERRAIEQ
WLTENDTSPITDVIIPHKFIMPNTTLLEAIKQWKSRK
>Sgl01917 E3_activity/RING/U-box 194.3 5.0
MSESKGTVQGQLIVGVALTGSRKSKFLLKWALEKFLPEGNVTFKLLHVYPKITIVPTPMG
TWMPVAQVREEVVTGYRQETEWKKQRKLIPYLKNLKAQKIKADLVLLESDDVPMAISLET
AKQSIRHLVIGVTTTSIFSMKNLSLARGGDLSHNISENVPSFCSVYLVGSDGKLQQLRPA
DAEPNVIAMDDRSNLSSTSTDSSSSPSSLTIGRLLKSTPSSPKYRGSANASDSSHPPSKS
KEPESLPTNGTGPKISARETIELKHFAFKETNFNSGNASVRSHSSSSGDSESWISDRTSP
GGSFVAAHSNIPSPIGTPPSRYFVSTTPTSSFVGTPANYAGTPPTGSFMATPPALSPMGT
PPTSSYMGTPPAHSRAGTPKGGSYVGTPPKVSFLGLSSGSDTGDSQSQITELDKLRIELR
HIEKMYELSQSSSIDERLDKISKERLEEALKLKEEKGKELARVETNKSNESQGEVTYTGE
GVERNKPRNKADTKDAQEAEEIKNKLKNLFASTAVQYQKFTWEEIMAATSSLSDEFKIGM
GAFGTVYKCKLHYTTVAVKVLHSKDSVTNKQFVQELEILSTIRHPHLLLLLGAVPEESCL
VYEYMDHGSLDDRLFKKNGKPPLPWYDRFRICYEVAGALAFLHSTTPRPIIHRDLKPANI
LLDHNLVSKIGDAGLGTMINVGPTNASLKTIYKETSPVGTLCYIDPEYQRTGRVSTKSDI
YALGVVILQLLTAKPAVGIAYVVEDAIDEGTLTEILDPEAGEWPDKETLELALLGLQCAE
LRGRDRPDLRSKMLPILERLNELADCARESISSSYTTTPPHYFCPILKDVMEDPYVAADG
YTYERRAIEQWLNENDTSPITNEPLPHKFIMPNTTLLEAIKQELLIVRCQEMAESTATDQ
SQLVVGVALTGSRKSKNVLKWALEKFLPEGNVTFKLIHVYPKITIVPAPMGTWLPAAQVR
EEVVNGYRKDIRWQKQKKLIPHQNNLNAQKIKTESILLESDDIPMALSLEITRQSIRHLV
IGLTSTSIFSMKHLSLTRGSDISQVISEKAPSFCSVYVIGSDAKLQQLRPADSEPDVITM
DDTSNLSSTSTDSSSSSLLDPLLKSKPPSPRCKGSVTASETFLFTSKPKQPESLPRNAVG
PKIEIARETLELQHYVFKETNFNSASVRSQNSSSGDSESWISDRTSPGVSFVAAHPNGPS
PICTPPQRSFVSTTPTGSYVGTPISYPGTPSTRSFTATPPAGSYASTPAISCAGTSKGGS
YVGTPPLLSHLGTSKGGSYVGTPGVSCTRIPAGGSYVGTPPAVSYAGMPTGGSYVGTPPL
ISRAETPTGGSYVGTPTPDSFLGIPSGSETGSSHCQKTELERLRMELNHIEKMYALSQNH
SIDERFLIPLDQLNEISKERLKEAKKLKEEKGKEIARMQKNKSTASQIGVKHIGGSTEKI
KHKNKVDIKASLDADENKNRLKNLLANPAIQFQKFSWNEIMEATSSLSDEFKIGLGAFGT
VYKCKFHYTTVAIKVLHCKNSVTNKQFVQELEILSTIRHPHLLLLLGAVPEESCLVYEYM
DHGSLDDRLFKKNGKPPLPWYDRFRICYEVAGALAFLHNTTPRPIIHRDLKPANILLDHN
LVSKIGDAGLGTMINIDPTDQSVQTIYKDTSPVGTLCYIDPEYQRTGRVSTKSDIYALGI
VILQLLTAKTAVGIAYMVEDAIDEGTFAEILDTEAGEWPEKETLELALLGLQCAELRGKD
RPDLRDKVLPILERFNEVATSARESASSAHTVAPTHYFCPILKDMMEDPYVAADGYTYER
RAIEQWLTENDISPTTNQPLSHKFVVPNNSLLEAIKQWNTLLALRRLSMSNTSNANQGRL
VIGIALTGSRKAKHIIRWALDKFLPEGNVTFKIMNVYPKIVVAPTGPTPMGTWLPVIRDP
VEIENRYRQEIELKRQKKLLPYLHFVYEAQQIQADIVLLESDDIAMAISNEITKQSIRHL
VIGGPSAGGIFSMKNYAQPTGDELGPIIAKSAPSFCSVYIIVDGKLQQLRPADSEQNVIT
LTIDDTNNSPNSSTDSASGSSSLTIGRLLKSKTSEPQYGGSANTSDLSHSNSQPKQPESH
SKNRPKFLTREVVELKHYDFKDSNISNGTGGSGSWASDRTSPTGSYIGNHSDARSSMGTT
PPSSYVGIPPTQFRNTPPAVSPVGTPPTGSYVNTPKAIYHSGTPPGGSYVNTPPKAPHER
TPRSVTFQGVSSGSETGASSNQISEIEKLRIELQHIAKLYEQSQNSSIDERLNGISKERL
EEAIKDKELARKEKNKYKAGKGEAVDTRGKSEQSKTKNSKDAQEAEESRNRLKALFASPA
VQYQKFTWDEIMEATSSLSDKFKIGMGAFGTVYKCKLHHTTVAVKVLHSKDSVTNKQFVQ
ELEILSTIRHPHLLLLLGAVPEESCLVYEYMDHGSLDDMLFQKNGKPPLPWYDRFRICYE
VAGALAFLHSTTPRPIIHRDLKPANILLDHNLVSKIGDAGLGTMINVEPTSASLKTIYKE
TSPVGTLCYIDPEYQRTGRVSTKSDIYALGVVILQLLAGKHAVGIAYLIEDAMDEGNLTE
ILDPLAGEWPKKETFELAVLGLQCAELRGRDRPDLRDKILPTLERLKEIADSARESASSA
HAATPPHFLCPILKEMMEDPYVAADGYTYERRAIEQWLTENDTSPITDVIIPHKFIMPNT
TLLEAIKQWKSRK
>Sgl01933 E3_adaptor/Cullin_RING/SCF/F-box 12.2 0.0
MEYPSFLFPLSSEEREERDWSSLPENVLFIIISQLFMLSDIFSFANVCSGWISVLKPRLQ
TLNIKPNMSFKRGLPMLLTLTNDSSEGTRNLYSIPDAVIYDLKIPMPYNNRCIGSSYGWL
IFIDCLSFVITLFNPFYFGSSKGTICLPPFVPAEDTSKRMKEDKFEFFSDYYICKAILSS
NPSSSTNGYVLMMIYGELRNLAYYNSEDSTWTCVATQEGIFDMIYHQGNFLAIDFWGQAY
VYEGKFIRPDANSTTEPVIGPVGGETRRYVVQTSDGIILQVVRLLSCTRTTTLATSTGMA
PAALNTLGFLVYKLVKWDDRLEWFPMSSIGDGALFLGDNCSTFVKASNFPGVTGDAIYYT
ADYPGDGSMYTAPHLFKDHQESGIYRLSDESFHRLNISFPEQKNHPPPIWLLPSL
>Sgl01957 E3_activity/RING/U-box 84.9 0.1
MGSNEEECEELHNYYADGTVFVAVGKHVKESESVLSWAVQKFAGKKRICILHVHQPPQLV
SFFDNKLNISKFKQRAIKALQESDIQKLHKLISQYVLFVSQWGVRADRMWIEKENIEDGI
IKMIAQHGIKWLVMGGAADKHYAKEMTELKSQKAIFVCEQAPVSCHIWFTCRGKLIYTRE
GVNNYPAVDTSLATGSQNLNMATKESDSRRLRGPSSEFSPKPEPLDSNVVTEEAEQLKVD
EAPAADGLTLDSDISTEISESDSLESDEISEEAELVRVIDSSADILSPESNRVIGESGPL
KVDQRVDESRSPPRLTYRERGSILRACSVDFSTDMEKQVVLSSSQNCSTSYGFVGSKNKD
HESEGNLQMIKFSSSLKSVLSEGKLAGKSKLQAPRKICDKLEHAASDAENLKQLVFQESV
KRWKAEEDAMDAKKKADAAENKYLDEMKQRKGVEEALVKQKLECERMKEEHEKYTVEFPM
VRDQCLGLESQIRESEISGKELEEKIISAVELLKSFRAERDQKRLECDKAVLELENLNRS
KLKRTSALSGIQFSTFSLLEIGEATCSFDPSKRIGDGRYGSIYRGILRHIDVAMRMLPND
GFLSQQMFEHGVEILSRIRHPNITTLIGICPEARCVVYEYLERGSLEDHLACRGKTPPLL
WQTRVMIVTELCSALIFFHKNNPPIFHGNLKPTKILLDANFRSKISDLGIFFLVAQKQAP
NISQDCNSVYVDPEFLKTGALTRESDIYSFGIIVLQLLTGILASEIVKDVKHAMRKDKFE
LVLDFSAGDWPINQARTLARVALQCCERNPSKRPDLASDVWSVLEPLRESCDVQTTCFQK
KGNSRPPSHFVCPIYQEVMKDPCTAADGYTYEGDAIRGWIDSGHTTSPMTNLKLSTCDLI
PNHALQYAIQEWLQHS
>Sgl02041 E3_activity/RING/RING 30.8 7.0
MASQLWEDHHVPPELKENLTELYPELTLEEALQHQESLYQSLTLGCVCQTARSSDNEPSS
SHGHSWAESSNSGSGGYDMALDEAVARSLQELDLEGEDDHVFIAEPFHTGSGNTETAAAD
TSASDAYQDDVDLDRMTYEELQSLGEAIGSESRGLSKTEISSLPCYTYKSSFFSKKVDIG
ECVICYTAYKNRDSLITLPCAHKYHKNCIEPWLVRSKICPICKMEVKLSFD
>Sgl02042 E3_adaptor/Cullin_RING/SCF/F-box 12.1 0.0
MGVGQSGLRSGLGELPESCVAEILGRLSPPEICQLAEVNKTFYGASLSDFVWETKLPSNY
EFLVQKLFHRRVDTLSKKDIFAMLCSPIRFDAATKEIWVDRRSGKMCMAISWKGMKITGI
DDRRYWNQIPTLESRFNVIAYLKQVWWLEVGGELEFNFPAGTYSLFFKLQIGKSSKSRFG
RRVCNTDGVHGWDRKPVRFQVCASNGQHAVSQCYLKEAGNWVCYHAGNFVVENHHLPMKV
KFSLTQIDCTHPKGGLCLDSVIICPSELADCLK
>Sgl02044 E3_activity/RING/RING 21.3 3.5
MEPVTEDSSNGVEENHSKNEYLMSDSGDDNKDDIDFEVEVLGDLENVETKPSFPVKEDSN
KVVDENHSENEYLISDSGDDSDFEVELLRDLEDVETKPSFLRFQEPHKGYKVMSEAEIRQ
CQERDINNISECLSITQAEAVLLLRHFHWNVDVIPEEWFNNEQELRIKLKLSDFPGFESF
DAKDMTCAICFGTFSQELIATALCGHIFCDTCWADYIRMAIEDGMASLMLRCPELSCTAP
VGRDMINMLAFDDDKDAYAGYFLRSYIEHNPKAKWCPFRCNCAVILEGDTSGSKVTCECS
NSFCFKCTKEPHQPISCAVLRNWQTESHVQSEIWSIGKTKSCPNCGTLVEVHDRHKRLEC
ASCNFQFCKLCLVSWLEQSEWEHVCSEGKFKQPDIEEEQVKEAQQRFNRYNIRLLQWETH
DMHMQADLEEIQILQNGQLKAIADKQGLTEADMSFVKDAWLQIIECKRFFEWACVYDYYL
KDGENEKQILFNYLTRRAEIILEHLYHRAFELITFLDIERPPEEFSTFRANLYSLTWVNK
NYFNNMAWAIENNLNMQTLCLVMESRMSRVNTSAPQKDGRKRPFSYSPSWDCAWCLFEND
ASAWSCVMCYHP
>Sgl02053 ULD/UDP/UBQ/UBQ_Other 36 0.1
MMRMRTKLTGLSPMNGNSNTANGDRHREVSNGDNRGVGGGGREAEGEGGPENWEMRPCGM
LVQKRVDGDQEPKPIPTIRVRVKYASIQHEIHINSHASFGELKKMLAGPTGLHHQDMKIF
YKQKERDSKEFLDIVGVKDKSKMSLVEDPLSQEKRYLEMRKNAKLEKAAKSISEISLEVD
RLAGQVAALESVILKGGRVAEKEVANLIELLMNELIKLDGIYADGDVKLQRKMQVTRVQK
YVETLDMLKIKNSTPATNGTHVPSENKQKISNGQVKSVRSKGYGQEKSSNSGKPPLPQQR
QRNSIGHSPLQPQAHKEQQSKNSTSGTVVTTQWETFENAPPLIPISTTSSGSATPKVVNP
NFPWDFE
>Sgl02069 E3_adaptor/Cullin_RING/DCX/DWD 93.1 3.8
MDFDANGGNKRVFHRLGNKQPQSHQFQQQKVCYHWQAGRCNRDPCAFLHTELPPQQRQNH
PSNQSFSSSTSTSYNGGSKRAHGLGGGGPQNDGFSSRKNPNFNNTWGRVGAGPPKKLERV
CNYWVQGKCSYGDNCKFLHSWSIGGSFSLLTTLEGHQKVVTGITLPSGDKLYTGSKDEHV
RIWDCASGQCVNAIPLGGEIGCMISEGPWVFIGLPNMVKAWNIETVTDMSLSGPVGQVYS
LVVGNDLLFAGTEDGAILAWKFNPATNCFEPAASLTGHTRAVVTMFVGANRLYSGSMDNS
IRVWNLETLQCIQILTEHTSVVMSVLCWEQFLLSASLDNTIKVWAATQSGNLEVTYTHTE
EHGILSLCGMFDSEAKPVILCSTNDNFVHIYDLPSFMERGKIISKQEIRAVQAGPSGLFF
TGDGNGQVRVWNWLTEPKKAM
>Sgl02182 E3_activity/RING/RING 37.4 6.7
MGGRYLAISAVCTAVSMIGLQCWTEITLEKFKADGLIGNNSFYAENASRIVELLLRSHAT
ITLLAVCVINVIVLFVLSIKTIFFGVLYTPETQKLVERLVNYIIYKGTFLPLIIPPTIFQ
AALWFTWLTVLCFLKMFQALARDRLERLNASPSATPWTYFRVYSALLLVLAFDILWIWFC
AAVSGPLVSSTFWLLFFEPLSIAFETLQAIVVHGFQLMDIWLHHSSEEISDCERSKFLDT
AAGSLWEWKSDVVRNLGFFLDMMTLLMALGHYVLIWWLHGMTFHLVDAILFLNIRALLSA
VVKRIKGFIKLKIALGALHDALPDATSEEIKTYDDECAICREPMAKAKRLPCNHLFHLPC
LRSWLDQGLSGIYSCPTCRKPLFVGRIESEASSHTRAVSSDEQLARQLSSGVDRVNTGDG
GVFPNQNQNSAEVNAWRGAGADSSWLQPWPSQGLDGAGPSTATRSAGLGRVQMMMRQIAS
VGETYAQNALEDTSWSLWPTNSSQATASNTAPAPVAHRFPAAAAAVHRRSVSQPANDSIA
NLLAMAETVREVLPHIPDEMIFQDLQQTNSVSVTVNNLLQM
>Sgl02210 E3_activity/RING/U-box 78.2 0.2
MEQKAAVENGKGSTSSRVIAVALNGGAKSKYIIRWVIDKFISEGNVSFKLLHVFPKITGV
PTPMGNLIPLPQVRDDVASAYKTEIEWQRNEMILPYRRMISQKKVPVELVLIEAEDVASG
ISTEIAQHGIKELVIGASSNGLFARRVKGQLLSSVISDCAPTFCTVYVVSKGKLEALRPS
KTETNGDVVECDSAATDSTNSSSRYTNSTFDPGSTYSDSPYSSPPGPVKQPEAISSAQNG
CSNSGTDSAESTSSQPSNTKIVDDLSSSVGTLTNQTSSLKTSNVDCEWITDQASTGLSYL
RPSDASSSKSQLASCESQENINEEIEKLKVELRHIRGMYNIAQNEAMDATRRLSDLGKLR
NEEALKLKQIGEKEEKAKELAKQQKERFEAAKREAVYARECAQRQVMQRRDAEQKAARDA
KERQKLKNVLGDPVYHYQKVTWDEIVSATCSFSDKLKIGEGSYGTVYKCKLHYSTVAIKV
LHSKEGANSKQFHQELEILSRIRHPHLLLLLGACPEQGCLVYEYMENGSLEDRLLRKNNT
PPIPWYERFRIAWEVASSIAFLHNNKPRPIIHRDLKPANILLDHNLVSKIGDAGLCTMLN
LDPSSISTLTLYKDTGPVGTLCYIDPEYQRTGLVSMKADVYALGMVILQLLTAKPAVGIT
NMVEDAIKEGRLMQILDTYAGRWPLKEAAEMALLGLQCAEIRRKDRPELKSILPILERMK
DVAEKARDSFAKNQVAPPSHFICPILKKVMEDPCVASDGYTYDRKAIELWLKDNDTSPTT
DFPLSNKNLIPNNTLSYAISEWKSKRRTQNGHYSY
>Sgl02252 E3_adaptor/Cullin_RING/DCX/DWD 31.8 0.0
MSYHDGGTLKSSSINGVKIYSLTGQQRSLATWLNPKKQRALRKDKDYMQRVELIQDLRFQ
TATTRIKASPDGAFLLASGIYPPQVKVFELRELSLKFERHLDAEIIDFQVLSDDYSKLAF
MCTDRSISLHAKYGAHYNVKIPRMGRDMAYDCWSCDLLCAASSPDLYRINLAQGRFLAPF
TTQSPALNVVSRSKLHGLVACGGEDGAVECFDTRTRSAVGRINAVSATDEDAEVTAIEFD
EEGGFQMAVGSSEGKVLIYDLRSSHPIRVKDHMYGSPILDIKWQRTLNSEHPKLISTDKH
IVRIWDPETGEGMTSIEPTGGAINDICVFRESGLILLALDSSQIPSYFVPALGPAPKWCS
YLENLTEELEENAQTSIYDDYKFLTKEELEKLNLTNLIGTNLLRAYMHGYFVDYRLYKKA
KAIADPFAYDAYIEQRKKEKLEKMHGERITIKRRLPKVNRRLASTLLEDEEAEKEIKDNT
DADAKKTSKKKKGLSSDILKDDRFADLFNNPEFEIDEKSQEYMSLHPVAPQKQTSLVDEH
FEPVLEDAMSLSDGDVSSASEDDGKLDKKSRGPRLYEVKDERHAQAFFDNVSLAKEAALP
LGERVAALPEEQLSSRVPNGVKVGPGGSREISFVSRSKAKYQEDEDDKDSRRSKRGVQSL
GLKPTNYEKRSRGGRGGRGGRGGRGRGRGRGRG
>Sgl02265 E3_adaptor/Cullin_RING/SCF/F-box 13.3 0.1
MNSLCYVYLPENIIFEILLQLPPKTIIQCKTVCKQLRFLKEQFILPPYYLLCSYDWLFAL
HLNHSHYRQCITSKELENQVLPLSSKSFELTFNKDALLSTCNGIMCFYLKEKNNLCLWNP
TIDETRFVALPYESYWIRKFYFAGFGYASSIDDYKIVLAAKYARHTSNDRRSLGVYSLRR
NQWRELDFDYYKSIAPEIYSGLGWRSGRQQSSSNGIRMESIVVNDALHWVIDSYICNINM
KFFLYKFDLLNECFEKVGVDLNKIISNIIVDGDNRLGPRQIEIGVIENRLVIYQLYSEFR
HSNPSNEFLVKRDVVKAWEMAEQYDYNSWKTKFRYVGDWDDIRDNHDLVRITGNGNVLVI
GGTYAEYESRLSFDQNSHKQRAQDVDFYAKHYVPSLVSPNNF
>Sgl02277 UBD/Alpha-Helix/UBA 36.2 0.1
MNGGPSGFNNAPVTRAVIISSAIFTIFFGLQGRSNKLGFSYLDIFQKPQLWKLIVSTYAF
TSTPEMMFGLYLLYYFRVFERQIGSHKYSVFILFSLAVSFFLGSIVLLLLKDPSALITAG
PYSLIFSSFVPFFFDIPVSTRFRVFGFHFSDKSFIYLAGLQLLLSSWSKSILPGICGIIA
GSLYRMNFFYIRRAKLPDFIVSLFSRLSWPSTGGTPSAPGTRTVSTAPPYAGRQVERNYP
APLAGTVEPSEDSVAMLVSMGFDLDSARQALVQARNDINVATNILLEAQSH
>Sgl02298 E3_activity/RING/U-box 27.5 1.7
MASSQNSEHETEPTQSTDPQLSISSSSSHVYMVGFVVAHIVGVQYYSGKISGREMVGLVR
EPLNIYDENAIKVLNTRGDQVGHIERNVAKVLAPLMDSNIVIAEGIVPKSPISSNKPRFK
ILVQIHLFARGEAFREIHSAILGGGLGFVSTREAVSFELSEAEVVKERRNCKDVKSVDEI
FENVGRKERVVVKLEPPKEVVITDLFDHQKEALGWLVGRENSDELPPFWEEKDGGFVNVL
TNFQMSNRPEPIRGGIFADDMGLGKTLSLLSLIAYDKYCCASVSVSGSGSASVGEISVNC
GGDGDNVEGSGGGKKSKGGRKGKRGGSSGSGNGSAARKKRKVGGVSEGVSVSLVSSNTTL
VVCSVSVMSVWMTQLEEHTRNNSLKVYMYHGVGRIRDVEELKKNDIVLTTYNTVSIDESQ
PDDPLHRMEWKRIILDEGHTIKTAEAKQSRAVTALNGKRRWVVTGTPVQNSSQDLFSLLA
FLKFEPFSNKIYWNSLVHRPLVQGDEKGLERLQVIMATVSLRRTKEQELFKLPLKSLQTC
YVELMPEERELYDRMEEEAKQFVKKYVNDGTVTHNYSTVLSIILRLRQICTDVALCPHDI
KSLLLPDNIQDVSNNPELLEKLLTLLQDTEDFDCPICISPPSDVVITCCAHIFCRACIIK
TLKLAKSKCPMCRHPLSESELYSAPPPAEPLDSTNTSSSPKPSSKVSVLVKLLSENRGVK
SVVFSQFRKMLLLLEEPLKAAGFKTLRLDGAMSAKKRKQVIHDFGVCGDDSPTVLLASLK
ASGTGISLTAASVVYLFEPWWNPATEEQAMDRVHRIGQKNNVKIVRIIARNTIEERVLEL
QEKKKELAKGAFGKKEKQETNVGDLCRLISLSA
>Sgl02304 E3_activity/RING/U-box 27.5 1.7
MASSQNSEHETEPTQSTDPQLSISSSSSHVYMVGFVVAHIVGVQYYSGKISGREMVGLVR
EPLNIYDENAIKVLNTRGDQVGHIERNVAKVLAPLMDSNIVIAEGIVPKSPISSNKPRFK
ILVQIHLFARGVAFREIHSAILGGGLGFVSTREAVSFELSEAEVVKERRNCKDVKSVDEI
FENVGRKEGLCVKLEPPKEVVITDLFDHQKEALGWLVGRENSDELPPFWEEKDGGFVNVL
TNFQMSNRPEPIRGGIFADDMGLGKTLSLLSLIAYDKYCCASVSVSGSGSASVGEISVNC
GGDGDNVEGSGGGKKSKGGRKGKRGGSSGSGNGSAARKKRKVGGVSEGVSVSLVSSNTTL
VVCSVSVMSVWMTQLEEHTRNNSLKVYVYHGVGRIRDVEKLKKNDIVLTTYNTVSIDESQ
PDDPLHRMEWKRIILDEGHTIKTAEAKQSRAVTALNGKRRWVVTGTPVQNSSQDLFSLLA
FLKFEPFSNKIYWNSLVHRPLVQGDEKGLDRLQVIMATVSLRRTKEQELFKLPLKSLQTC
YVELMPEERELYDRMEEEAKQFVKKYVNDGTVTHNYSTVLSIILRLRQICTDVALCPHDI
KSLLLPDNIQDVSNNPELLEKLLTLLQDTEDFDCPICISPPSDVVITCCAHIFCRACIIK
TLKLAKSKCPMCRHPLSESELYSAPPPAEPLDSTNTSSSPKPSSKVSVLVKLLSENRGVK
SVVFSQFRKMLLLLEEPLKAAGFKTLRLDGAMSAKKRKQVIHDFGVCGDDSPTVLLASLK
ASGTGISLTAASVVYLFEPWWNPATEEQAMDRVHRIGQKNNVKIVRIIARNTIEERVLEL
QEKKKELAKGVFGKKEKQETNVGDLCRLISLSA
>Sgl02332 E3_adaptor/Cullin_RING/SCF/F-box 13.9 0.0
MSDINPGFGPQLWSEILKFLPVKVLGQCMCVCKSWKTLIKSSTFVAAHIQNYAQSEANSC
LLYRQFTNAPENHEQYTVFLDSAQKESVPKPLHTFTCPFISHKYFRVVGSVLGLICLSDD
LFGYSYLVIIWNPLLHKYIRLPIPRVTYLTGVSHISAFGFGFDSKKCSHKVVRVNYMRDE
KALDTTPPFVEVYSVHEGSWRRVSANNVVDICICDYWWSQCFLNHAVHWVAWERDGKTRA
FYRNCLLLFDVEEEKFKKMKLPEALAKEFTMNLRVSECGAKLSVLHSVQKGGTLGNEMER
CEIWVKEEYNVGSSWCKMYCIEKNSSPRLGWIQCLRRNGDVLGFTKKGELMSYDPLMKQI
NGLGVRGCWRSWSTCSYTESLVLLDKKNDVGTYDVARGQRKKFEILVRSNGSLDMGEKNT
DNEDVEHEADKHGFIINHREKAFLLDQMRKFDAGRMTEDPSDFLAMAGLDFGDLKSMAES
YVADHR
>Sgl02389 E3_adaptor/Cullin_RING/DCX/DWD 35.1 2.1
MLRLRAFRPTNEKIVKIQVHPTHPWLVTSDASDHVSVWNWEHRQVIYELKAGGIDERRLV
GARLEKLAEGESESRGKPTEAIRGGSVKQVNFYDDDVRFWQLWRNRAGAAEAPSAVSHVT
SALNSLAPATKGRHFLVICCENKAIFLDLVTMRGRDVPKQELDNRSLMCMEFLYRSTAGE
GPLVAFGGSDGVIRVLSMITWKLARRYTGGHKGAINCLMTFMASSGEALLVSGGSDGLLI
LWSAEHGHDSRELVPKLSLKAHDGGVVAVELSRVSGGAPQLITIGADKTLAIWDTISFKE
MRRIKPVPKMSCHSVASWCHPRAPNLDILTCVKDSHIWAIEHPTYSVLTRPLCELSSLVP
PQALAPSKKLRVYCMVAHPLQPHLVATGTNIGVIISEFDFRALPPVVALPSPPGSREHSA
VYIVERELKLLSFQLSNTANPSLGSNGSLTESARPKDSEALQVKQIKKHISTPVPHDSYS
VLSLSSSGKYLAVVWPDIPYFSIYKVSDWSIVDSGSARLLAWDTCRDRFAILESTVAPRM
PVIPKGGSSRKAKEAAAAAAAAAAAASAASSGSVQVRILLDDGTSNILMRSIGGRSEPVT
GLHGGALLGIAYRTSRRVSAVAATAISTVQSMPLSGFGSGASSFNTFDDGSGSGPSSTQN
FQLYSWETFQPVGGLLPQPEWTAWDETVEYCAFAYQQYIVISSLRPQYRYLGDVAIPYAT
SAVWHRRQLFVATPTTIEVVFVDAGVATLDIETMKMKEEMKLKEAQARAVAEHGELALIS
VDGPKSDTNDRIPLRPPMLQVVRLASFQHAPSVPPYLTLPKQSKIDGDDSGLPEDRRANE
NAVGGGGVAVAVTRFPMEQKRPIGPLVVVGVRDGVLWLIDRYMRAHVLSLSHPGIRCRCL
AAYGDAVSAVKWATRLGREHHDDLAQFMLGMGYAVEALHLPGISKRLEFDLAIKGNDLKR
ALQCLLTMSNSRDIGQETSGLDLTNLLNVAAKKENIVDTVQGIAKYAKQFLDLIDAADAT
AQSEIAREALKRLAAAGSVKGALQSDELRGLALRLANHGELTRLSTLVNNLISLGLGREA
AFSAAVLGDNALMEKAWHETGMLAEAVLHSHAHGRPTLKNLVETWNKMLQKDIEHTRTTK
TDATAAFLASLEDPKLPSLGDTGKKPPIEILPPGMSSLSLSISAPKKPLPATKALQQEPG
KQLLLEAPPTAAPINGATPPAADSGESTVPPPVDSNQSGAPPAEPSQSEASPAEPSQPQA
TPPESSQPGATPPESSQPGAAPESSQPGATPPESSQPKEASSEAEAPSTEVSDQPKLEGT
TSADKSEAGASNQVEYSKLEASKPVDSSQSGAPLPANLNQPEASPATIVSTQPILDSKAF
ELQLLGSTGPEVTKPSSSRSVFADLEQLM
>Sgl02397 E3_activity/RING/RING 33 13.3
MEEEFQFHNHIPTNCLRNYFTSTFSRCFSLTPCINGGYSELRIEDDSDDGSLGDQAYCKP
FIVLDVIWNLGFVLVSCFMLICTISEKPSTPLRVWICGYALQCLFHVGFVYIELRRRNHG
RVPLPESQSHLSYSFVKRLESANTIISSFWWVFGFYWIVSGGQSLLQDSPRLYWLAVVFL
ALDVFFMIFCIGMACIVCLAVFCCIPIVAIAYAMTIREGASEDEIRQLPRYRFHQSYTPL
GSVNATDELTLHFDNSECCICLTRYVEGSELCNLPCNHNFHYGCISRWLRINATCPLCKF
NIKAKGDALV
>Sgl02403 E3_activity/RING/U-box 29.3 2.4
MAVYYKFKSAKDYDSIAIDGHFISVANLKERIFESKHLGRGTDFDLVVTNAQTNEEYLDE
AMLIPKNTSVLIRRVPGRPRMPIVTQPDEPKVENKIEDDSLVKSNFTAVDSSVYRDYDGT
EMDDEFGNDLYATIPEMTPGQSNNQMQDLVPPSKADEDSKIKAFIENSGFDWQRQGNDGF
GPGRGFGRGGRGGRGFGRGGGLEKKAPPQGYVCHRCKVPGHFIQHCPTNGDPNYDVRKVK
PPTGIPKSMLVATPDGSYALPSGTSAVLKPNEAAFEKEIEGLPSTRPVGDLPPELHCPLC
KEVMKDAVLTSKCCFKSFCDKCIRDYIISRSICICGASDVLADDLLPNKTLRDTINRILE
SGNSSADNGGSALHIQDMESARCPQPRNPSPTQSAASKGDQMLPPRTEGTSNLKESVDGI
KPSDASQQQVQQQISDKGKITKVPDVSEATHESASVKEPASQGSALPVEEEVQQKVATSE
AGKKKKKKKKMPLPVNAPDMQWMGGMPPGMDGYNNNNMGPSAFNPCWPGMQPGMDGFMNP
FGGNMPFNMGYGPGPMDMHFGNVMPPDPFGNVMHPDPFGPQGFMMHGMGMPPMRPPPPQR
DLAAEFGMGMNVRPPLMSREEFEARKAEVRRKREMEKRIESREPPKDRDYSREVNSSANL
HAMKSKPKPPPASRSPSQDRYDSFRDRERARERVSVDRDRDRDRDHDSHQRRTTTHSRHE
RVSPERTRRESRDPEVPRPTLKRKSEHHERDHSHEREREREHRDHRSHTKPSSSKPVPSS
DVVSPSSDKKKASVFSRISFPEDEPVKKRKVSAEPKPKPKAVSKDHEPHHHKAAASSSMA
NGHHETSRKSVAASDMDCESSDDERHFKRKPSRYEPSPPRREEWMSVADEEDGRRHRKHR
>Sgl02407 UBD/UBC-like/UBD_UBC 116 0.0
MATNENLPPNVIKQLAKELKNLDDTPPEGIKVNVNEDDFTTIFADIDGPAGTPYENGVFR
MKLILSSDFPHSPPKGYFVTKIFHPNIANNGEICVNTLKKDWNPTLGLRHVLLVIRCLLI
EPFPESALNEQAGKMLLENYEEYARLARLYTGIHAKPKSKPKQGAISESTTALNVDQKNN
SSAQTANQENTGASTKAKSLQDQPVAVGTVASALPLNENGAVGSSTAPTVAAAASVVQKK
DGVKAHAEKKKIDARKKSLKRL
>Sgl02440 E3_adaptor/Cullin_RING/SCF/F-box 19.9 0.0
MKTNLLDLPQECLSQIFSLTSPLYVLRCSLVCKLFNSVANSDLVWKNLLPSDLHPLVQDL
STTPTKHLVLLLCRSFILLGDRNMSVSLDECTGKKIYVLGARTLTFAQSDCWLWESPLPE
SRFLEVAELFGVTELHITGKISTKLLSLNTTYRIHFSFMLQPDSSGFGKHPVRVFVSKID
ASGACLGGSQDNSKTFYLKAPVKGKRGDIFDDDTCVDTFDKPDDVETEDTFRHCSDAPRW
LKIDMGKYFHKEDSDVAMLEMTLMGTEIGLRKSGLVVHAIELQPVD
>Sgl02445 E3_adaptor/Cullin_RING/DCX/DWD 29.7 0.0
MVVRAEKIVPDIEQDGEELDANVKKFLRGEGANLEALQDKKLKGQLADKEKLYKRSAKAA
ASVEKWLLPSEGGYLEPDPDSIEKTWRVKQVDIGKEVDILSLKNQFDMVLPELGPYNLDF
TANGRYMAIAGRKGHLGVLDVKNMSLIKEFQVRETVRDVVFLHNELFFAAAQKKYPYIYN
RDGIEVHCMKEHGAVSKLQFLKNHFLLASINKLGQLRYQDITIGEMIANFRTRLGRTSVM
QANPYNGVIGLGHSCGTATMWKPTNPNPIVKMLCHQGPITALAFHPNGHLMATAGMEKKI
KLWDLRKFEVLQTMPGHAKSLEFSQKGLLAASTGSFLQVMRDVSGSQNYSRYMTHSMAKG
YQIQKLSFRPYEDVLGIGHSMGWSSILIPGSGEPNFDSWVANPFETSKQRREKEVRSVLE
KLPPEAIMLDPKKIGTVKPQRKKKLTRKEREEEMEAAVEAAKGVELKYKMKGRSKAGKRA
KKRQELVEKVKKQFIEQNAKEDEEVSHKKRQRTSEEVVELPKSLQRFAKRKAD
>Sgl02455 E3_adaptor/Cullin_RING/DCX/DWD 31.1 2.4
MFRCRRIMSQQQVDEYDYMADENEVADFIDEVDGEFYARDDGNIGMEEYDLLTKVTDTSA
ANARRGKDIQGIPWDRLNITRDKYRLTRLEQYKNYENVPSSGDSIDKEWKSKEKGGNYFE
FFYNSRLVKPTILHFQLRNLVWATSKHDVYLMSNYQAMHWSSLTRNLSEVVNFAGHVSPS
EKHKGSLLEGFTQTQISTLAVKDNLMVAGGFQGELVCKRLDNQGISFCARTTYDDNAITN
AVEIYNSLSGCYHFMASNNDCGIRLYDMERFQLMNHFRFPWPVNHTSICPDRKLIAVVGD
HVNGLLCDSQSGKVVSTVQGHRDFSFATAWHPDGRVFATGNQDKTCRVWDIRKLSESVAV
LKGNLGATRSIRFSSDGNFMVAAEPADFVHVYSTKANYERRQEIDFFGEISGVSLSPDDE
CLYIGIWDRTYASLLQYNRKHAYQYLDSFV
>Sgl02564 E3_adaptor/Cullin_RING/SCF/F-box 17.7 0.6
MANSNKRTNSTPELAKAVVARVPGAGDDRRTLAGCVKRPRRSTEENDAASSRSNCFPRDI
AFSILQLLPATFLSNSGRLVCKQWNEIISDPLFVRAHTQLHLLLPSSLRIFVQDVDLRYA
KHMQAYYLRTHDADDNDTDTDIDIDIDTDTDSDSGSESDATKLMLPFPATILDSCNGLLL
LHHVTIRKELRVVNFATREIVTLPPLLEAGVRVLVRPYAALAYVPSSGQYKVVYVSLVSN
SKRAAYLRDAQDALAHSRIHKVKVLICTLGVDKTWRTIDFGKDITLMGKGEQSLLLCQPL
STTAGYIYWLNFDHYMFGLALDVDAETMHQFTAPKDYKLKGIHTFYSIKMDTGVALVGYR
RNYRNEDWKVWEMIDPKNGTWGTSISFNTDHMQLILLDQDYHMIRGKVPFSISLRTGDLW
LYSEVDGRYALVCYNLKTAKLRFIDFVPYVEWPNRHALPQLHVNSLISLKNL
>Sgl02572 E3_activity/RING/RING 35.6 5.9
MAPVRYCSREDLLSSLVCKDQGVAQGPFSDDDDDDSSSDGINYTRATIVFAIIAVVILVI
YFSYDFLYVHIYLRRIRNNIHGNNRPAKPKGLDPNVLKTFPVFVYNDEAEAEAARPGIAL
EDCAVCLATFEKDETLRMLPKCGHVFHVECLDPWLVGHSTCPVCRANLVPQPGDVARTMG
GGVEARRDEVVVDIREQYEVVEVNRPVEVNGTRVVCQIS
>Sgl02589 E3_activity/RING/U-box 32.4 0.1
MGDRTDDLMNLDLNLGPGAPPSPVLGPGIGPSSGESVNVDGWESSYVREALNLRQRTRHL
WRWRRQVHLPLEPHSLRLMVESDGNGGDPGGGSGAEGEDNGGTLQAGEGSVTAERRNYEA
VKTCENNVIAVENGSIAAKEDVEKPNSEEGSFFDCNICFDLAREPVVTCCGHLFCWPCIY
RWLHIHSDAKECPVCKGEVTLKNVTPIYGRGTYVHEPEEDAGIKVPLRPTARRVESLRQS
IQRTASSFRMEEMIQRLGARFELTRDFFQNPNGVDGDTDLSSRVSFLNRFMTTRALRREQ
NPPIPPEEVVVDLTQERPEVPARRLPPLTYRRGQLHRNAAAAAAAYSARANAPDRFELWT
SSARSQDPQPPSVDDRDSFSSIAAAIHGESQTVDTAVEIDSLVSLSTSSSRRRHEPSRAS
DVDSGDSRAPRRRRLN
>Sgl02659 E3_adaptor/Cullin_RING/DCX/DWD 112.9 13.5
MSQVNQSSPSVILATASYDHTIRFWEPQTGRCYRNIQYPDSQVNRFEITPDKRYLAVAGN
PHIRLFDINSSNPQPVMSYDSHTNNVMAVGFPSEGSWMYSGSEDGTVKIWDVRAPGCQRE
YESRAAVNTVVLHPNQTELISGDQNGNIRVWDLTANSCSCELVPEVDTAVRSLTVMFDGT
LVVAANNHGTCFVWRLLSGTQTMTNFEPLHRLQAHKGYILKCLLSPDIGGSNSPKRYLAT
ASSDHTVKIWNVDNRFTLEKTLSGHERWVWDCVFSVDGAYLITASSDGTAKLWSMISNEV
IQTYQGHHKAVVCCALNDGAEVSS
>Sgl02801 E3_adaptor/Cullin_RING/DCX/DWD 130 14.5
MEIDEENPSSASAAEPTASVVDTEMLATQAVPDPATAIAGPESLSLATTITSVAPPLVIP
GAVPPSVPPSVTPLSAPPSVHVPPIASLPVVPPVVPRPLAPLPVRPPVLKPPVVQNGEMK
ESESDDEDDDDQDSGKGAHGSTAEYEVTEESRQVRERQEKAMRDLLMKRRAAALAVPTND
MAVRARLRRLGEPITLFGEREMERRDRLRMLMVKLDDEGQLEKLMKAHEEEQEAAAAKDE
VDEDMLQYPFYTEGTQELLEARKFIAQFSIVRASQRLQRAKRKRDDPDEDEDAEVDWALK
QAGTFVLDTSEIGDDRPLWGCSFSKDGNFLSACSSTGVAKVWSMPQLKRVSALKGHTVHA
TDVAFSPVIDNVATASADRTARLWNTDGTLLRTFEGHLDRLARIGFHPSGKYLGTASFDK
TWRLWDVESGAELLLQEGHSRSVYGLAFHRDGSLVASCGLDSLTRVWDLRTGRSVLALEG
HVKPVFGVDFSPNGYHLATGSEDNTCRIWDLRKKKSLYIIPAHSKLVSQVKFEPQEGYYL
VTASYDTTAKVWSSRDFKLIKTLSGHESRVTSLDITGDGQSIATVAHDRTIKLWSSTVPV
EENSMDVG
>Sgl02806 E3_adaptor/Cullin_RING/DCX/DWD 99.9 10.3
MDHKISKLSNEEDEDHLSLDKSPSFHHFTLQSSPSFHHFTLPSSPLSPQSPESLWSQSPS
RTLHSSPFSRSPLYYSCISSLRHKDQIYSIAVCGDLVLTGSSSRRVHAWHLSSHDFLEKG
YLQASSGEVRAMVALGNNMLFTSHKDHKIRVWEIGNCNNFRPRKVTTLPNIKYFIVFRPI
ITPQHRLINSKTTSSQHKDRISCMAYSHVEGLLYTGSFDKTVKTWRLNEKKCIDSFIAHN
NNIHDIVINQKNGYIFTCSSDGTVKMWLRVIGEFSHALIKVLTFHKNPIYAMALSISPAS
QNQNSFLYYGSFDGSINFCELETLSCQCNNHERRVIQGHQFSVLCLVALENLVISGSEDS
TIRIWRRSSGERRVVSHECVAILEGHRGPVRCLGARLQDKSTTSLLVFSTSLDQTFKVWR
VKHNVQEINNNLVDRRSNADDGNIKEGSNSLEFEFVERSPVLSQEWVKKRGSISQCS
>Sgl02821 E3_adaptor/Cullin_RING/SCF/F-box 17.3 0.0
MFSSYNNNGSMQNSDDNNNLIKSPTWEVLELISHHLDPQTLAIASCVSKTWSTCFSSDHL
WAPLCTTHFPSLTSSLSAVAATSLPRCRLYGLGYSAALRRRPKKPRKPRLDPNRLLFAVS
VHFPAGEVDVLKSCDAMRWDPHGLFRFDLEVAERREWTVEELKAVKVTWTVAEREWKAVF
TVAEDASGNLSSAVDGLFSKELPSPGCCSSSMSSGLVADIRFGLKDQDGHLFSWIKGSRV
SKIEKVSVGIMDVRNWRHISLDDGLLYLEHFLQV
>Sgl02848 UBD/UBC-like/UBD_UBC 126.2 0.1
MTLLSCLLSSFKRHKKHDSKRSSSGSSMGKSQTIGTITRNRVYSEMTRMSVQNVVVSHWS
YGLVDVHDPFNLQGIIIGPSDTPYDGGVFFLSINLPHDFPFKPPKIKFRTKVFHPNVTSD
GTVDIDILSNEWTPIYTIDNLLVLMCCFLSQPYNVLDSSNYVCHLYSNHRKLYNKIAREW
TFKYAMT
>Sgl02854 DUB/USP 266.9 0.2
MNLESSNSTSMDVDASCSVQSEGYSNLERGVNVTVEHEDDADIDQMPMVCASSKYEPPKP
FFTEDEREMNPLELREQACKNKEEEERRMEKEKGKPEGGRKVRLPPEDLATTSKPSAPPV
EEKKEIITGKRVSKKAARSALKEKDKKVSTSSSKTVSQEGNVNYVIANDGPVTKKEKKAC
VHLEKGVNLGIVCSKIESAESTGCEYCREGVNDRKAGKGKGKHGKKKGASDSRAKGKATW
ICLQCGHFSCGGVGLPTSPQSHALRHMRQNRHPLVIQMENPHLRWCFSCSTLLPVNKVED
NGEEIDVFLDIVKLLKKQSSKSAKAPSVDVEDVWFGSGSVLSEVKAENKAVTVANGKDSY
AVRGLVNLGNTCFFNSVMQNLLAMDSLRDYLLNFDGSMGPLTSALKKIFVETCSDAALKN
VVNPKSLFGCVCSKAPQFRGYQQQDSHELLRYLLDGLSTEDMSAKKKEITSAVTATFVDT
FFGGQTSSTVCCVICGHSSVVYEPFLDLSLSLPTKKPPSKKAQPVFRAKKTKPPPKRGGR
TRPKLNKNGDLGPALSGCNTSANVEASSGIKDDMRPVANGCNTLITAESASSMKGDSLSC
ALSADLVDTNNGFQRNVSVTQDDYTCAQVPQFAAQDDGMPWLAYLEPTSQGKGAQDVDSF
SWLDFIEPVSSLDGRNLAVEDEDLLGSLHGNHESDSMQLTAKSSVEDNLAKVSGMKFDNQ
DAVSVPNTAKSGGEASVPPADMVRKVESIVDDWGDERPVMVQDNEVLLLTYKEDGPMEGE
GMGIDADMPSSSIVDGEDTLGFGGLGDLFDEPEAVESETGVSNTLVNESLGNGYIAGNNT
ESDPDEVDDTDSPVSVERCLVQYTKPELLSGEHAWHCENCSKLLKEERQKVRKNQKKAAL
IQRNMHSDACCSSKVLQAKSHLCIDSSASILAPCNNGNSDTDENLKRFEARETNRLCPCL
PQEEEERLVRETAHLTASGSGVCFGPCDESNLDGRSLDCHAVFNNHIPIECSGLSEENEL
VEEEEDVDLKCVKVMRDATKRILISKTPPILTIHLKRFGQDTRGRLSKLNGHVVFKEFLD
LRPYIDRRSTEKDKCIYRLVGVVEHSGSMRGGHYVAYVRKGDRQSGRSEVQNRQGHSVWY
HASDAYVREVTLEEVLRCEAYLLFYEEVKLC
>Sgl02861 UBD/Alpha-Helix/UBA 37.1 0.1
MSGVSLRCGDCGVLLKSVEEAQEHAELTSHSNFSESTEPVLNLVCSSCGKPCRTKTESDL
HTKRTGHTEFVDKTSEVTKPISLENPTSSTPMDVDASGSSQSEEMVVPDVDKQLLEELEG
MGFSKERATRALHCSGNSSLEGAVNWIVEHENDADIDQMPMVPASSKNDPPKPSLTEEEK
KVKLLELRERARKKKEEEERKMEREREKERVRIGKELLEAKRIEEENERKRLIAFRKAEK
EEEKRALEKVRQKLEEDKAERRRRLGLPAEAPAAAAKPSAPPVEEKKLGLPVKPVTKAEK
MRECLRSLKKNHMDEDARVKKAFQTLFTYAGNVVKNPDEEKYRRIRLSNQAFQDRVGGLK
GGIEFLELCGFEKIENGEFLFMPREKVDEAVLNSAGKELQSAINNPHFGIL
>Sgl02926 E3_activity/RING/RING 30.5 11.0
MMSSISFIVMLLIMIIIPTIIYTFFFLINCPPNPFHFLRRNRLNDNNNARRSKIANDEDD
EGDGSNKDKTNNDIELVVASSENLVKETECPVCLSVFVIGEELRQLKICKHLFHRSCIDK
WLSTHCNCPVCRAFVRNHAKNMKEDQRNSSNNNRVFASRNMDRDDFWQGLPDSAGLV
>Sgl02955 E3_activity/RING/PHD 38.3 3.6
MAIARTGVYVDDYLEYASTLPAELQRLLNTIRELDDRSQGMINQTRQHTKYCLGISSHSS
KKGYNGEGDDAAIEKLRKEIEGVQDNALSLCTEKVLLARQAYDLIDSHIKRLDEDLNYFA
EDLKQEGKLPPDEPAILPPLPIVTAPKPERQRGVYGTPQSRRFSYRERDWDRERDKDSEL
MPPPGSHKKDFPVPVDIDQPIDPNEPIYCVCHQVSFGDMIACDNEGCQGGEWFHYACVGL
TPETRFKGKWYCPTCRDLLQCRS
>Sgl02956 E3_activity/RING/PHD 37.6 5.3
MAIARTGVYVDDYLEYASTLPAELQRLLNTVRELDERSQGMINQTRQHTKFCLGISSQSS
RKGYNEENEEEEDDDDALERLRKEIDRTQDNALSLCTEKVLLARQAYDLIDSHIKRLDED
LNYFAEDLKQEGKLPLDEPTILPPLPMVTAPKPERQRGGYGMPQSRRFSYRDRYWDRERD
KDSELMPPPGSLKREFPVPVDVDLPIDPNEPIYCVCHQVSFGDMIACDNLGCQGGEWFHY
ACVGLSPETKFKRKWFCPTCRELPQFRP
>Sgl02998 E3_adaptor/Cullin_RING/SCF/F-box 17.9 0.1
MENEEETKKTKNSVCSTYLPQEVMFEILVRLPITMGSETLPRCKAVCKQWYSLITDPLFT
RTQYHFYKNQFHLPSWCLLSAHVSSFVVHLNRNEFRYNVTTKDFVDHPIPVSSSHFKLSY
GRDVLLSSCHGILCLFLEDKNKLCLWNPTIDEVRFVSLPYEINRFYYVGFGYASSIDDYK
ILFAVEYTAGHPGTNCKSVSVYSLRRNEWRELDFEYCNSILTELELYLGLGFQTSTDHRN
AMRVESTVLNDALHWILVPNIYNKNIKALLYKFDLVNECFEKVVDLNSIDILIDDDDDEL
TPIQTEIGVSENNRLMIYKLYYEEDISKTMAMKRDVVKAWEMVDQYDYKSWKTKFHYVGI
WDGMSDDHDLVQITGNGNVVIIGGKFAENDEISLQVLQNDDLDFFAAHYVPSRVSPNKF
>Sgl03016 E3_adaptor/Cullin_RING/SCF/F-box 17.6 0.1
MENEEETKKAKNSVCSTYLPQEVIFEILVRLPITMGSETLPRCKAVCKQWYSLITDPLFT
RTQYHFYKNQFHLPSWCLLSAHVSSFVVHLNRNEFRYNVTTKDFVDHPIPVSSSHFKLSY
GRDVLLSSCHGILCLFLEDKNKLCLWNPTIDEVRFVSLPYEINRFYYVGFGYASSIDDYK
IVFAVEYTAGHPGTNCKSVSVYSLRRNEWRELDFEYCNSIVKELELYLGLGFQTSTDHRN
AMRVESTVLNDALHWILVPNIYNKNIKAFLYKFDLVNECFEKVVDLNSIDILIDDDDDDD
ELTPIQTEIGVSENNGLMIYKLYYEEDISKTMAMKRDVVKAWEMVDQYDYKSWKTKFHYV
GIWDGMSDDHDLVQITGNGNVVIIGGKFAENDEISLQVLQNDDLDFFAAHYVPSRVSPNK
F
>Sgl03107 E3_adaptor/Cullin_RING/SCF/F-box 21.6 0.0
MAKNGLMISEGGKKKISKMMMMKSRKRVKIEKSYKKEEENENENDPMEVLGEDIMMKIMG
NLDARSLARSLLVCHSWFFLSSSDSLWSPLCKQLWIGKAHIPRWSKARGLSKLASYSRAV
TDSKRIRIMKEDLCDHAWDFHFTKEAPEYWKNLDPYWGGLGPPMHRYFHSDGSQTADPED
KVWGGHECSYTIVTSVVGDGKIRDNYVRINRWPRLVVSRRDDWGWEMSNVIFAYSSIPDA
DKGGGTGPMLKIC
>Sgl03175 E3_adaptor/Cullin_RING/DCX/DWD 41 0.3
MRDPMWVDDANAPSTSNPLPRIHESCSTAKRSGNNVFNLLARREIAPRTKRSTKRLWGES
SERGFDAGCHIFEAGRDSRRSLISWVEAQSLRHLSAKYCPLVPPPRSTIAAAFSPDGKTL
ASTHGDHTVKIIDCQSGNCLKVLSGHRRTPWVVRFHPTCTGLLASGSLDHEVRLWDANTA
ECVGSRDFYRPIASIAFHAQGELLAVASGHKLYIWHYNERGDLSIPTVVLKTRRSLRAVH
FHPHAAPFLLTAEVNDLDSSDSSMTLATSQGYVQYPPPTVYVANVNASEELPVTSLPLLI
WPLLPRNDGRMSFQHSDGSGGPNIVQQRVGPSSSVRLLTYSTPSGQYELLLSPVESSDIS
SVSDVRPDGQSAEMEPSAPESVVDAMETSDVQPEERNTQLFPFGDPAYWDLPFLQGWLIG
QSQAGQRMIRPVNSNSHELSSQSEMLNQDPVAAPAMQMGTSYTRASSRSTARHRSSRLRA
AVSTSGAEGAAPQDQEDPQPVISRIQSELATSLAAAAAAELPCTVKLRIWPYDIKDPCAH
LQADKCRLTIPHAVLCSEMGAHFSPCGKFLAACVACMLPQVEGESEIQMQANHDASGAAT
SPTRHSIPAQPVMYELRIYSLEEATFGLVLASRAIRAAHCLTSIQFSPTSEHLLLAYGRR
HNSLLKSIVFDGETTVPIYTILEVYRVSDMELVRVLPSAEDEVNVACFHPSVGSGLVYGT
KEGKLRILHFDSSSNLNCTFSCFPDESPITCFRMLISRIVLTYRHTVKLIRTTMTDSKAI
GSSWDEFSFSSLKCVVIRFLLYHAYTEVVMWWMQFGGIGAALGPPPD
>Sgl03294 E3_activity/RING/RING 28.6 16.7
MEDDVGKHRDEVPQSPRMFVSDSKGYALSGRIMLSAIIILFGVVVIMVCLHIYARWYILR
ARQRQVRRARRRTHLVFYIEPDGSNVNSNGVPVQSRGLDASVLKSLPILTFADVESEGKV
EALECAVCLSEFEEAENCRLLPKCNHCFHVECIDMWFHSHDTCPLCRAPVDSGDVAAPAV
ENPPSEEVVVEVGELTQSQPAELTQEMGSSQGEVKEESLSTSSSSLSTRKGLDLAGVSAI
EVPRRSHSFCFSGSNLDESGPSRSPGFKSPTSRIMSLKRILSREKRSPLPSPSGVGSSCC
EIDIESGRVDTPSQWLTPR
>Sgl03394 DUB/ULP 157.9 0.1
MKTDLFLWGTVRQPWLRDEPDYYRCSTQIDTHIAKKRRISCVTSPSKVIATPPSVVSRLS
RYPKPEKLPREVHAPCRLNRVGFQSGRLKREDSGIREKKLIMGNVLYRGYEKAKTNVFGV
LRFVKVDKNTEVIDLDAEPKKDGISKDWGEVEIVEDGKEVRSPVLDDHKAVDSDGSVLKT
NELGRKVVQNDVVEETLVVSDLTNVEDAGKDLGLRSLGREAYEELLSKVNRKYTSNLSSL
GFEIGSYEARLQSLRSLHKEKEKKKSEELKKPGEDLLREPFVPLTEEEDRDVTRALSNSN
RRKILVTHENSNIEITGEILQCLKPGSWLNDEVINLYLELLKEREKREPKKFLNCHFFNT
FFYKKLIGGRNGYDYKAVRRWTTQRKLGYGLTECDKIFVPIHKEVHWCLAIINVKEKTFQ
YLDSLGGVDSHVLRVLARYFMDEVKDKSGQEINVSSWKEEYVEDLPEQHNGFDCGVFMIK
YADFYSRGLGLHFSQEHMPYFRRRTAKEILRLRAD
>Sgl03396 E3_adaptor/Cullin_RING/BCR/BTB 25.6 0.0
MAEHQQQQQQQQNRCNSLVEQDHHHNYFMKMSVSMSQPQHQQSEDNDPSSVELRAVDCNL
ASLCDHIQLQGFNNGVFSDIVVNAMGSTYHLHRLILSRSSYFRNMLHGPWKEASAPVLSL
QIDDNNVNSEAIAIALAYLYGHYPKLNDNNAFRVLAAASFLDLQELCAICTDFIITELWT
SNFLAYQVFAENQDYGMHGERVRNACWGYLSQSGFLELKEVLPSLSCQTLHALLTSNELW
IPSEEKRFELALYTLLKKSALNKAETEEKQSASLETGLTDHCHSSDNKGKTIIDACCTRN
SEADMGRVHQLSSSEPNLGAAYPNNIEQSSLLTYYSDSDRSRPSSSYVRMPVSFMANGQG
GDGALVEGPSEESICCQFSNSNWISGNNSRECSSSSINSSCNEIMPDEWGRNDLAFPWGG
RTVGRRQVKSYGKGNCGLKGEEYGTFISVFEGGSVLYCNMSFEALLDVRKQLEELGFPCK
AVNDGLWLQMLLSQRVQEIAAETCKNCCLLSMTCACKQPYTFSHGSATTSYYVQAPDQHN
PHGNIGDLYVAGPANVEGNGVFRPVRVHVRGSNDGLAGIGRGATLVPASSWCPTRFVFSR
VPFGVGNRNGQQSLANDDLELRPDQHGDMSGDGLTALVGLSDGGRNVVNVHGGQTERTYE
MDLGNGFIGTSAAGPSSSGVQLRESADHQDIDSQWENTSNASISLDMKTPLSHFPPFRFG
VEFDDVHRLNDGQVKHSPEAFYAGSLWKISVQAFNDEDPQGRRTLGLFIHRRKAEIMGPQ
RKVHLYVDTREKVTARYQREVMVFGSFKQAGTLLPKAPKGWGWRSAILFDELPDLLQNGC
FRVSAVVQLV
>Sgl03463 E3_adaptor/Cullin_RING/DCX/DWD 122.5 15.1
MQTSTCHYRSQWNDDSEHDLYDSRSASFSSLPSLPRVPVLTVQPNQQSHLATTLSHCVTT
LTGHSSNVFSLTLAGKYLYTGSSDNEIRVWKRNPFSYEAGDESLTNDNLVAVGKSAVKSL
VVLGNQLFSAHQDCKIRVWKIKTQEQAKNMRYEKQATLPTLGDRTKRLLNPNNQVEIRRH
KKCTWVHHVDTVSALAFSQDQSLLYSVSWDRTLKVWQTSDFKCLESVKNAHDDAINAVAV
SYDGDVYTGSADKKIKVWRKHSGNKKHTLATTLEKHKSGINALALSPDGLLLYSGACDRS
ILVWEKNDHYDSMELVGALRGHTKAILCLAAVDDLVFSGSADKTVRVWRRVGINYSCVAI
LEGHQGPVKCLTAAADSYSQHNNTVSSNYLIYSGSLDCDIRVWQVLVSK
>Sgl03533 E3_adaptor/Cullin_RING/DCX/DWD 20.3 1.1
MHSHHLLILFCKGPNPRPLSTTQVHSFLFQLLKGVAHCHSHGVLHRDLKPQNLFLDKSYT
HEVCNLNLCCDFCVILELCVIAEFWKLQIVTLWYRAPEVLLGSTHYSTGVDIWSVGCIFA
EMVRRQALFPGDSEFQQLLHIFSFGTPLLTVYFFSSFVLLPNESLLGTPTEDHFCLFQIV
VWKLIRQHGTLPITSAEQKPDVMSTLVDVHSQECLEYEAEIVSKLAGHQGSIFCLSWSDD
GSKLVSVSDDRR
>Sgl03578 E3_activity/RING/RING 31 16.2
MEDDVGKHRDEVPQSSHMFVSDSKGYALSGRIMLSAIIILFAVVVIMVCLHIYARWYILR
ARQRQVRRARRRTHLVFYVEPDGSNVNSNGVPVQSRGLDASVLKSLPILTFTDVESEGKV
EALECAVCLSEFEEAEKCRLLPKCNHCFHVDCIDMWFHSHDTCPLCRAPVDSGDVAAPAV
ENPPSEEVVVEVGELTQSQPAELTQEMGSSQGEVKESSLSTSSSSLSTRKGLDLAGVSAI
EVPRRSHSFCFSGSNLDESGPSRSPGFKSPTSRIMSLKRILSREKRSPLPSPSGVGSSCC
EIDIESGRVDTPSQCLTPR
>Sgl03949 E3_activity/RING/RING 12.8 0.2
MDTSWIDLRPSNPTFYNGCMEFLELAKETQIEGKTRCPCNKCKLSKWLPVNDVGGHILFH
GFYKNYRNWIFHRVGEESNIHQSLGEQSNVIGRDDMEGLLKSMFRANNPHSIHEPIEDPF
DESDFRKDGLHDIDVESGVAHEDDDCDEFQYENTNEEAKFRRLMDASQEALYEGCSTFSK
LSFLLHLFHLKCLYHWSAESFTKLLELLIDAFFQIKEFPSFYYEAMKLINDLGLRYEKIH
ACPNDCMLYWGEFAQRMSVMFVIHQDGKR
>Sgl03986 E3_adaptor/Cullin_RING/DCX/DWD 17.8 0.0
MRSKPITNPITAAIMLSIFLFFLIFFSGFFQNPSSASPSLRDPIANPTKPDPFTNLLGAF
RKWDSQMGCPKFREKFPTWGSSNGSNSLQVSGFDENGGIGCHKELKLKHVNILVKGWTWI
PDNLENLYNCKCGLSCFWTKSEVLADPPDALLFETATPPLQCNAVSFSRNCKLLASSSED
TTIALWELYPPRNTTGAV
>Sgl04036 E3_activity/RING/U-box 114.4 0.2
MRRHENSSKDRQTISQIIKIIKEISSSPECRNSSKRLYSNLVRRLKLLGPLFEELVDRQE
EDDDDVDDNDNEFVLSIDQVKGFDSLLNALISAQGLLKRVHESSKLFQAVQREKVSAEFL
HITGQIEEALSMISYDTLDLSEEVQEQIGLVHAQFLRAKARTESSDLQLEMDITKVQEEA
EPDAAVLQRLSHSLHLLTMDDLRKESRVFHEMVITSNSDLGDSFEKMSSLFKKLNDYLLT
LNPEIGMCDVDKGIIKHRSPVIPDDFRCAISLELMKDPVIVSTGQTYERSCIQKWLDAGH
KTCPKTQQTLLHTALTPNYVLKSLITLWCESNGVELPRLQGTSKTRRTGTSASSCDKAAI
GALLKKLAHGNIEEKRAATGEFRLLGKRNADNRVCIAEAGAIPLLVELLSSSDSRTQEHA
VTALLNLSINDTNKGIIVSAGAIRDIVEVLNNGSMEARENAAATLFSLSVVDENKVAIGA
AGAIRALIALLVEGTPRGKKDAATAIFNLLIYQGNKIRAVRAGLVDPLMRFLKEVDGGMV
DEALAILAILASHPEGKTAIGQAKPIPLLVELIRTGSPRNRENASAILWTLCMGDVSNLK
MAKELKAEPVLKDLCENGTDRAKRKASSLIELLQRVEEPTD
>Sgl04450 UBD/Alpha-Helix/UIM 16 2.2
MADQEEEELQMALKMSMQPSNSPPEPKRSKPRDSVNNAASIDGAPPASEESPELKSRRLQ
RELMAAAAERRRMANAPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
>Sgl04459 ULD/UDP/UBQ/UBQ_Other 32.7 0.1
MIKGELKKLLAQQTALEPEDQRLFFRGREKEDAETLLNAGLKDHSKLLLMERPASKEKKM
EEARKKEEISKACAAIAGVRAEVDKLSQRVFSSIPELCFFGRVVSCLLLEASVLSGTKVD
EKEFIIATELLMVQLLKLDSIEAEGEAKTQRKNEVSSFLFVNFKTCFVCYAHFC
>Sgl04549 E3_adaptor/Cullin_RING/DCX/DWD 30.9 0.2
MASGLCKGRFMNEVESLCGHTTPVESLAFDSAEVLVLGGASSGTVKLWDLEEAKSEFVYV
LHFIYPPFVRWVVSGGFDNVVKLQLQPSQVNYHSDLVSVRVTLSMSVILRETRLGKGKGN
AGGSSQKGGAEEEKYWDLSGLSLKGTLAPELGYLDNLKSLILHTNHLSGVIPAEFGRLTK
LEVLDLSDNNFTGVIPTDIAKIVSLKRLLLCGNNFEGIIPPEFEEYSSLSELQYDEYLAS
VTNMMN
>Sgl04659 E3_adaptor/Cullin_RING/DCX/DWD 16.2 0.1
MDNDNIHSLGESDEEDPPFDPQQEVDKGDPEDVAMHDLEGEKEVQLGACVRKLSIVVKWN
DVPQSLNNAFWDETVNLFHIEATVDKRNIFISAVAQRFRDFKANLVSGFITKKRKRSKKE
RDNKTPPDIWPNVSKDDWEAFVAQKTTPQAILRKEEQSNKQCKVEEETPCKLLLQDPKSA
EECLVIVANGHARPPREGFKVHGVPLPQGHYAVCVDHFQESRKLYQIPIPISSVDINTVE
EAHGTYVAWPFNLVLQKLAHKSNGLSKEKGKEHSIDNTIKLLGAGAFAFHPTLEWLFVGD
RRDTLLAWDVSTERPTMIGIIQVGSQLITSVAWLPALRLVATLSNDGALQVWKTWVVLNP
NRVPMAGGLVAHGGPRWLRRGSRWPTRDRQRQAVTTAAAGSGHGGYGGSGSGHGHGPRDD
EEEEEEEEEEEEEEEEEEERRRRRRRRRRRRRRRRRRRRRRRRRRRKRRRRRRRRRRRRR
RRRRRRRRRRRRRRRRKKKKKKKKKKKKKKKKKKKKKKKKKKKKRRRRRRRRRRRRKKKK
KKKKKKKKKKKKKKKKKKKKKKKKKEEEEEEEEEEEEEEKKKKKKKKKRRRRRRRRRRRR
RRRRRRRRRRRKKKKEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEKKKKKKK
KKKKKKKKKKKKEE
>Sgl04904 ULD/UDP/UBQ/UBQ_Other 33.5 0.3
MGAHTQQFCPSATSVDGQYLMIKGELKKLLAQQTALEPEDQRLFFRGREKEDAETLLNAG
LKDHSKLLLMERPASKEKKMEEARKKEEISKACATIAGVRAEVHKLSQRVFSSIHSELCF
FGRVVSCLLVSSLEASVLSGTKVDEKEFIIATELLMVQLMKLDSIEVEGEAKTQRKNEVL
ISQSLPTYNNVLCSSAQTGVEDGRHATSYAYACTDDSSVFEELRKEVVDQNLEETKPKVV
ARFGKLLFHR
>Sgl05076 E3_adaptor/Cullin_RING/DCX/DWD 92.7 28.3
MEIDFQDYQLSAQLHGHEDDVRGICVCDNAGIVTSSRDKTVRFWPLDSANNYKEMPSPKI
MVGHTSFVGPLAWISPNDEFPEGGIVSGGMDTLAMVWDLKSGERVHVLRGHQMQVTGIAL
DDHDIVTSSVDCTLKRWRNGKVVDSWEVHSSPVQAVIKLPSGELATGSSDTTLKLWKGKT
CVHTYTGHSDTVRGLAVMSDLGVISASHDGSVRLWALTGEVLLEMVGHTSIVYSVDSHVS
GLVASGSEDCSAKIWKDGVCVQSIEHPGCVWDVKFLENGDLVTACSDRVVRIWTTHADRM
ADPVERDSYSSLLSNYKISRKTVGGLKLEELPGLDSLQVPGTSDGQTKVVREGDNGVAYT
WNMKDYKWDKIGEVVDGPGDGLKRPVLDGKEYDHVFDVDIGDGEPIRKLPYNRSDNPYDT
ADKWLLKENLPLSYRQQVVDFIMENTGQKTFSFDSSFRDPYTGSNAYVPGQTSTNNAVSA
KPTYKHIPKKGVLVFDVAQFDGILKKLSEFNSTLLSDEDQKQFSLTDVETSRIGAVVKIL
KDTSHHHSSSFADVDIELLFKLLTSWSVAMIFPVIDIMRMVILHPDGASKLFKHVNGGND
ALMEIIKKVTTDPVIPGNVLTGLRALTNLFKNTCFHQWLQTHRSEILDAFSCCYNSNKNA
QFAYSTLILNFAVLLIEKRDEEGQSQVLSAALEIAETENLDVESKFRALVAIGSLMLDGS
VKQIALDFDVESIAKGAKSSKDTKIAEVGADIEVVANGS
>Sgl05088 E3_activity/RING/RING 24.9 14.8
MAAKPPEHEHHPSSFPPATSFSSSSILIHQSSTIDFSPPLIAMVVVAAAAFLFITYSRRI
SRHIFPPFLRLYRHHRRRARRFLPSSDLASPPAPYQSSSDGFYVYSPCPYGLDDSTIKNI
PLTKLKFIELLDEDGFHFHDCAVCLVDFQEGECIRTLPHCCHPFHVDCIDMWLRSHATCP
LCRAGVFLSPPPDDSHSHPHVQLSPVMAARVRPSFDQGILLESMFLEHLQEGNNSEEIQE
IFSPESERRAIQSERSSNNRRELDSLLKRSYSFGFERRGSYPSVSEERLVMEPATTPYHH
HRQRRSFFWRKRPSSSTPFRSMAKSRVFSFRRTMKSQSQSQSPAFFRRKGYISMWESSES
LRYGSSRRMKASPGPFSSSRMRLGDPEALISPERYNRHRR
>Sgl05165 E3_adaptor/Cullin_RING/BCR/BTB 69 0.0
MGSKEWQGKENSSDRKGQKRKLEQQQDERDSAIVTDEALRREVRTQVDILSANFSWSEVD
RASAKRATHLLAELAKNEEVVSIIVEGGAVPLLVKHLEAPPSSGEDDGLKPCEHEVEKAS
AFALGLLAVKPEHQQLIVDVGALPLLVDLLKRHKCGVNSRAVNGVIRRAADAITNLAHEN
SSIKTQVRTEGGIPPLVELLEFNDAKVQRAVAGALRTLAFKNDENKKQIVECNALPSLIL
MLKSEDAAIHYEAVGVLGNLVHSSPNIKKEVLLAGALQPVIGLLSSCCSESQREAALLLG
QFAATDSDCKVHIVQRGAVPPLIEMLQSSDLQLREMAAFALGRLAQESHNQAGISHSGGL
VPLLKLLDAKNGSLQHNAAFALYGLADNEDNVADFIKAGGLQKLQEGEFIVQATKDCVAK
TLKRLEEKIHGRVLTHLVYLMRAGEKAVQRQVALALAHLCSPEDQRSIFIDNNGLELLLG
LLKSTSSKQQHDGAVALCKLASKAMTLSPVDAAPPSPISQVYLGEKYVNSATLSDVTFLV
QGKRFHAHRICLLASSDAFRAMFDGGYRERDARDIEIPNIRWEIFELMMRFIYTGSVDIK
PDIAQDLLRAADQYLLDGLKRLCEYTIAQDISLDNVSSMYDLSDAFHAVSLRQACILFIL
EQYEKLNAMPGHSSLIQHILPEVRNYFLRILTKPNA
>Sgl05311 E3_adaptor/Cullin_RING/DCX/DWD 57.4 0.9
MLTIIGPLKNATHPRLTFLCGGGSHRFSVELDCEKIQLHNQLLTSNQGFPKVMRDYKIGN
YNKVNQSSFNSRFLAKSNRCLLQDFHGHVADVLDLAWSDSNVFQFLLSSSMDRTVRLWKL
GSDVCLNIFHHTNYVTCVQFNPTDNRYFISGSIDGKVRKWGVLEQRVLDWAEIKDAVTTA
CYQPNAQAFVVGSLNGSCIFYETKRELFELSAHVQLYNSKRSATKRITGIQFSPKDSKIK
KHGATRR
>Sgl05315 E3_adaptor/Cullin_RING/SCF/F-box 15.2 0.0
MEVTLSSFLSSQSFIVAFAATLLCGIFAVRFSLSSSSKIDSSRRKNFTTESKDSNSSNNC
VSDCNCSCNGVVLRPDPTVAAVNGGEMPAVAMVAAEKQTGASMMEQLVPEITTHALSYLD
YPSLCRLSMTNSLMRKAANDDNAWKALYHKDFTVEQDSVRPANGWKAYYAATRALVNINA
EFFNIIRERSLPAMSRFWLNADYVKCVHVSGELITGYNAVMQSWQIAFNWNQETDGFQIR
DVRARVLTDMAWITMKTYVGMNGGPYSVTNVFEHHNGKWYMVHHHCSLMLVDEDVEQQIV
HG
>Sgl05338 E3_adaptor/Cullin_RING/DCX/DWD 21.4 2.1
MKAKAVKLREARKSCINGFYGEACWLLLVMMRALNSSTLLILQLQEFLKDIKDPSLAWLA
FDPLNEYLASLDTKGTVIYWELQSGNLLHTLKGVAPDTSHDMSIMNVISWTPDGDFFICS
RYLATSDSDNQVLIWDVDKRLDIDRQQFDERICSMAWKPTGNVLAIIDVMGKYGVWESVI
PSSMKSPTEDVLQSKYNNGLLLFDEEEQEQSTSASFSDMGEDNFVESMPHTKKRLRKSSL
YEESLEKDIISEELDSHQRIKSHRKPAKNHKECLDGGDGKPKSMTVQNFSKLQEPFQPGA
TPVQPGTKCFLCCNMLGSITIMQHDGNSHIEIYFHDKSQGPRVPAMTDYFGFTMASLNEN
GSALANPRNGEKNSTLMYRLFSSWANNSEWSMRFEHEEVKVVALGTGWVAAT
>Sgl05402 E3_activity/RING/RING 25.3 11.1
MTTTDDELTKQLQQLRTQLNKKQTFESAISSIKSLLIENYPNSSPPIKTLFYDVVCRVAT
VLRTRYTFPGYLVAGVELLETAEKLIATPSEKSHLKSCISNIRQTLNQDDENEEPLQRNS
NGGYLFEGHLTVDQEPPQPNWLVQQNLLTALASSQSQPNGENSDTVSSLMRGLVESLDVS
MIENLEEILPLMEGDGVGSRAAPPASKEVVGKLPVIKVESEEMLKNKFGGEGAECCICKE
KLGVGDEMQEMPCKHLFHPPCLKPWLDEHNSCPICRRELPTDDHKYESWKEREKELEEER
RGAANAVRGGEFMYI
>Sgl05417 E3_adaptor/Cullin_RING/SCF/F-box 20.2 0.0
MEAFPPEIIEEILSRLPVESLLCLKTVCKSWNSIIKTPAFIKSHLNKTLISNSHPRLLKS
STDYLKEKKLSLYSAKIDSDDSQTDDRRLSFSMLNHPPDEFNSGTVFGSCNGVVSIYDYS
KTNVLLYNPFTKSRRILPAKALPPSYKSKMGGRMLYGFGYDSKTDDYKVLRIAQGYRSLD
HPFNETDHVCSVYSLNNDCWKSVYGIVSKQYYFFLYTYDGVFFNETLHYLMISTTY
>Sgl05436 E3_activity/RING/RING 25.3 11.1
MTTTDDELTKQLLQLRTQLNKKQTFESAISSIKSLLIENYPNSSPPIKTLFYDVVCRVAT
VLRTRYTFPGYLVAGVELLETAEKLIAIPSEKSHLKSCISNIRQTLNQDDENEEPLQRNS
NGGYLFEGHLTVDQEPPQPNWLVQQNLLTALASSQSQPNGENSDTVSSLMRGLVESLDVS
MIENLEEILPLMEGDGVGSRAAPPASKEVVGKLPVIKVESEEMLKNKFGGEGAECCICKE
KLGVGDEMQEMPCKHLFHPPCLKPWLDEHNSCPICRHELPTDDHKYESWKEREKELEEER
RGAANAVRGGEFMYI
>Sgl05443 E3_activity/RING/RING 28.9 9.8
MAEFSTKLKESLILSMSPSTTPGSTIDDDFEDACSICLEPFSPHDPASVTTCKHEYHLHC
ILEWSQRSKECPICWQTVALKDSASQELLVAAEIERKARARRASTNRTTYSYQYQEPDTG
YDSHWTDESDFNERMMQQLAAMMSRARQAHRSGRQRSSGRSPSPDPEIMFPSRGSESALH
PNTPEECNSAYGSPGGSSPTASTQPQFPAIQLSANLSSGSAPRRVVNQPSRPPQSQSPDS
SQRQRSSELLAFSESIKSKFSAASARYKDSISKGTQGFREKILARNSSVKELSKGVQREM
NASIAGVSRMIERLDLKSKRGTQSGDDNHGGETSTLMSKGKGVLDHILASSQENCVATGH
ENSQATCSISSHKDVAREQRT
>Sgl05464 E1 303.9 0.0
MHTDLDIVELEQSLTDISMADSTANSRSRDLDKLLLRPGHLVGPNFQPGSELRDDIQEYA
RVLVVGAGGLGCELLKDLALSGFKNLDVIDMDTIEVTNLNRQFLFRLEDVGKPKAEVAAK
RVMQRVSGVNIVPHFCRIEDKPLDFYNDFNIIALGLDSVEARSYINAVACSFLEYDENDN
PKEETIKPMVDGGTEGFKGHARVIIPGKTPCFECTIWLFPPQVKFPLCTLAETPRTAAHC
IEYAHLIKWDEVHSGKAFDPDDPDHMQWVYQEAVKRAELFGIPGVTYSLTQGVVKNIIPA
IASTNAIISAACALETLKLVSGCSKTLSNYMTYNGVDGLHTKVTEFSKEKDCLVCGPGVL
IELDASCTLQKFIEQLEEHPQLHLSKASVTYEGKNLYMQAPPVLEEMTRSNLSQPLFELM
EKVSSGTIHATGTSSKNDKKTFGSRKLRVTFKGVDGMTDMDTAGGA
>Sgl05491 E3_adaptor/Cullin_RING/SCF/F-box 12.5 0.0
MSVQGENICPLSSDVFYDILRRLDGATLASAACTCAAFSSISKEERIWEDVCYSLWPSTK
NDDVSNLIRSMGGFRKFYADCYPLIVNNDLALVPLDTFLEYPEEWPEADYYEDLEEYDSV
SPSDFVSLVDIRYKDKPIYSKVLPGFSDSDVLGRWFYNSPFHIDLGKSDVSDSVGEVIIS
VADGLPPIKSIDDERKDGKVWLELQDRLRLSWIIINKKVKQAANISSLIPLGVQRHWPSD
TDFLVRFGSVLPAGDILPCQVVECIFLAKFRMFDDSASGCINLELTQVSMQLEDMEGFHV
NGRNSLMVLKKALSCRKSKNYSEVLESCNLYSRVRSEIKEEKLRNESRIDKMCILSGVLA
VVTFWFCIL
>Sgl05568 E3_adaptor/Cullin_RING/DCX/DWD 19.7 16.5
MDDEDKDMLYSFSNTPPPNRKAHSLSTHLRYGTNTNNPSNSTPTSSTTPNANPELSSSSS
KRANQLRNHSLDEARITNAITNHHQNRHLGGPFYNTDYSDEDADFFPYASSSMSTTFARS
YDHSVSLPAVGSSEPEDDDHRISMPEFTANGGTGIFKAPTRSAVHPTRPPALELRPHPLR
ETQVGRFLRTIGCTESQLWAGQENGVRFWNFRDAYEAGVGFAGRNTKRGDEDTSPFYESA
VTSPTLCLVVDHGNRLVWTGHKDGKIRSWKMDQNVNNSNGGDGGGGNGNGGGGGGSEDSS
PPFREGLAWQAHKGPVLALIISCYGDLWSGGEGGVIKIWPWDSIEKSLSLSAEEKHMAAL
LVERSNVDLRSQVTVNGVCNISSSDVKAMLSDHARGRVWCATSLSFSLWDARTKELVKVY
NIEGQIENRAEMPVPQDQQPAEDEMKVKFVSQSKKEKPQGFLQRSRNAIMGAADAVRRVA
TRGTGAFNEDTKKTEALLLTSDGTIWSGCSNGLILQWDWNGNRVQEFNHHPSAVLCFCTH
GPRLWVGYASGVVQLLDLEGNLIAGWVAHSSPVIKMAIGGGYVFSMAIHGGIRGWHLTSP
GPLDNVIRSALSAKELLYTRKESIKMLVGSWNVGQGKPNPEGLKSWLGSAVSDVGIVVVG
LQEVEMGAGFLAMSAAKETVGLEGSAIGQHWQDAIGRVLDEGMVFERVGSRQLAGLLIAI
WVRKNLRMHAGDLDVSAVACGFGRTIGNKGGVGLRLRVHDRIICFVNCHLAAHLEAVNRR
NADFDHIFRTMVYSRQSHLLNVAAAGASSASQVIRTANGANGNSDEGGRPDLSEADMVVF
LGDFNYRLFGISYDEARDFVSQRSFDWLREKDQLRAEMKAGKVFQGMREAMIKFPPTYKF
ERHVPGLGGYDSGEKKRIPAWCDRVIYRDCRTGPVSECSLNCPILASIQMYEACMDVIDS
DHKPVRCKFSVHLARVDRSIRRKEFGEAMNTSEEIKTIIRNISEIPETEVSTDNITLQNQ
DTSVLQITNNSQNEKAVFHIICEGVCIINVNGEPSELRPRASFGFPFWLEVTPSCGVIYP
EQSMEVTVRHTESHTLGDVVEGVPQNWWSEDTRDKEVVLAVQVRCNSTMELSSHRIRVRH
CYSARTSRTDSSRTNSSRRGNNGSHYRSESQRRDNNPDMVDRG
>Sgl05572 E3_adaptor/Cullin_RING/SCF/F-box 17.8 0.0
MMETSKHPNTNNGDKQDLLSSLPEEILIKILSYLPIEAAVTTGVLSRRWQHLWTLVKAFD
FNNLTVGKPIDQVPSIINHILPQLKSPQLQTFVIHLDDQSPPVTDNNAFYLGDQHDKHLK
LLSKFCSHIGSWIKLLCNKKVQVIEVLVFGRFIASCSATLPSCIFQCESLESLALNMPLR
VTLPKYISLPNLKVLYLSHLNEKHRQLLGKLLNSCPCLEDLSLAGYIDNPTVEGHEISVV
IASENLDALYIGFWKVSHGDMLVNVDAPKLKYLRVDDISRSRVKFIKEPSDLSEASLGTN
FMNPGLTLGMDLFGVIRNVRSLVIDSVTIDAFNRLYDDQANSSVVSQGFCSLTELVCYKM
SPACWKQLTCLVSCAPKLESLTYEIKVTGFYSDVNINDVFVHANDAPQFPLQHVKRVEIR
ECFGRTVDDTMMDFIKYCLSNASVLEQFDVKLPVTGTESSDSIELLKRNELELCEILCNI
PRSSVSCRIKVSSWCASSESIG
>Sgl05662 E3_adaptor/Cullin_RING/SCF/F-box 19.5 0.0
MAELPTDIIIKILSKLPVKSLLRFQCVSKSWKSLIKSPNFINSHLNQTLISFSNRHLLIS
AIHTSLHSSELDHLLINNQLALSFSQLHPPLKPFNFVGSYNGVVCISDISQNNFFLFNPL
TNSRHKVPTSKIQVPEFNLMVFGFGYDRINDDYKVLRIVQGVGMLDGSENNALVYSLKAN
SWRFIKSIQFYLYHGYCHGAFVNENLHYLVTKEPDYLSVFIAIFDVRTESFSVMDCPDYD
HHRFVSNSLNTAFMLVELGGCLCLLMSSYVGDGGGVGDEVMVAPAEYIDELDARVLDCVD
FWVMKEYGNNESWVRLFSIRHPESIGSYKLIKPLVYSNDGSRILLEIDNSRYIWYDPKSK
IVERISVHGVLSNGGLKAGIFIGSLVSLEDKVVPQKEGLLMKKSKNYELTEDATAGICLK
LCPFGVLFILYTWTKLVVRG
>Sgl05663 E3_adaptor/Cullin_RING/SCF/F-box 19.4 0.0
MAELPTDIIINILSKLPVKSLLRFQCVSKSWKSLIKSPNFIKIHLNQTLTSYSNRHLLVS
VEYSSLHSSEFDLTNNPPSLCFSALNPPHEKFHFVGTYNGIVCISSISKRENFLFNPLTN
SCHKLPSAEIPIPEFNMTLLGFGYDRNNDDYKVLKIIQGLGKLDDSKNKAQVYSLKNNSW
KCIQGIPYALYYGYYDGVLVNDYLHYVVTHEPSSEHLLIASFDLLTESFSHMECPDYDDQ
FTSFHSVFTLVELGGCLCLLINFYGNDEMLFDDDDDDLLDELDARVLKCVELWVMKEYGK
KESWVRLFAIRHPETMGSSRVIRPIVYSEDGRRILLEIDVLRYGWYDLESKNFDLINAHG
LPKGLINTKVFIGSLVSLEVEDKLLSQKEAVPMKNNKK
>Sgl05664 E3_adaptor/Cullin_RING/SCF/F-box 18.7 0.0
MATLPTEQITEILSRLPVKSLIKFTCVCKSWYSLIKSPKFIKLHLNQTLISNSNRFLLIS
YSSKQSSNNNLCRNHLVLSEFDTNPNDNQLKYSEIHHPLNHREITLLGDCNGVVCITDKP
KNNVFLYNPMTKSCRKLPRNRTSKNNFDNQSLVFGFGYDPETDDYKVLRLLQDSHYNDVN
YKEAELYSMRNNSWKYVEKIPYFLLFLDRHGVYLNGAIHFVVVTAELQMHRKFIASFDFK
TESYSLMECPDYGDKLGASLDMGEISGCLCLMVMDRIILPFDEIGFRMDSAELWVMKEYG
KSESWVRVFSIPATATSVGMYLHARPLAYSKDGKKVLIEYDYLGIGWLDLETQKFVMSEG
VPKPPIFSRVFQGSLVSVGDDKLKFEEAAAIPRKNTKKKNVDNFLSSGFKLKL
>Sgl05668 E3_adaptor/Cullin_RING/SCF/F-box 13.8 0.0
MEALPPVIIEKILSGFPAESLLCLKTVCKSWNSIIKTPAFIKRHLNQTLISNSHRRLLKS
LKDNSQNRKLSLYSAEIDSDSPTIDRRLSFSMLNYPLDEFVHATVFGSCNGVVSIREHSR
TNNVLLYNPFTKSRRILPPEGLPLSYKSERDRRLLYGFGYDSKTEDYKVLRIVQGYSFNE
VDGHVCSVYSLNNDCWKSVNWIVSKHFYFFPYPCSDGVLVNENLHYLVMSSTNESMIVCF
DLPTESLSLMDFPNNLMMSGCESSLAEFDGCLCVMCMYFTLNNILVRAD
>Sgl05702 E2/UBC 102.8 0.0
MTSLSGDTTNPDEKFPQFDAVPDASDHHFAGKHQNPSFSSSNSALHKKIMQEWKILSKDL
PETIFVRVYETRVDLLRAAIVGARGTPYHDGLFFFDIAFPSDYPSKPPLVHYHSFGLRIN
PNLYSSGKVCLSLLNTWSGKKSEKWDPNNSTILQVLVSIQALVLNERPYFNEPGYSAWSG
RTYWEKKSLAYSEDVFLLSCKTMLWVLRRPPKKFEPLVNQHFKERAQFLLTACDAYRKGC
VKIGSFETVSWRVKGVETSVKFKGLMNQLYGDLVIAMSKTGASVGQRVEQVREEKEKNAN
EKAVAAAKKKQGEINVSEVGKNVVKKLKKIVFHGLMIKNKNGKSKEIINKNEISKEISV
>Sgl05735 E3_adaptor/Cullin_RING/SCF/F-box 21.1 0.0
MEAFPSEIIEEILSRLPAESLLSLKTVCKSWNSIIKNPSFIKSHLNQTLISNSHRRLLKS
PKIMDYSKKRKLSLYSAEIDSDSATADRRLSFSMLNHSLDDYVEVFGSCNGVVSVCNYSR
TSVLLYNCFTKSRRILPAERLPPGYKSERGRFFYGFGYDSKTDDYKVLRIAQGYRSLVYP
FYETDHICSVYSLNNDCWKSIHGIVSKQYYYFPYPYSHGVLANETLHYLVTSNISYELDD
LKRPGRMIVCFDFRTESFSLMDCPNHEDENNNDNNNNNLMIRSCKSTYLAELDGCLCSMF
THFSMNYITRERPVFVRADLLVMKEYGNKESWSKVFSINGDQLNIVCRSFTGVKPVVYSK
DRRRILIDINGGIVTGWFDLETKKFEELEHHGLPDEYFDTRYFMGSLVSVGHSKLHSIGT
TEETKTEEKVKK
>Sgl05736 E3_adaptor/Cullin_RING/SCF/F-box 18.8 0.1
MEEFPPEIIEKILSQLSAESLLCLKTVCKSWNSIISTHEFIKTHLNQTLISNSHRRLLKS
SMDSKKRKLSFYSADLDSDSRTDRRRFSYSMLNHPLEVDYATVFGSCNGVVSILDFSKPD
NVLLYNPFTKSRRILPAPSYNNNNNKWELVDLLYGFGYDSKTEDYKVLRIVEKYRYLVNP
PKSFYEADHVCSVYSLNKNCWKSVSGTVLNRYAFSSPSSHCVLVNETLHYLVMSTANDYP
RRMIVCFDLQTDSSSLMDCPNHDDKNNNNLIGRRDSYLAELDGCLCVMFMYFSMNNYNVR
ADLLVMKEYGNKESWSKVFSIRNDQLTSVCTSFRRIKPITYSKDRRRILIDIDGGFVTGW
FDLESKKFKKHKHRGLPFRHFDTSSFMSSLVYINESLFYLKHVLGMYIYSLLFRLTVESG
IEFGNNWNVMGAWDDSLQHAAASLVGMGAALLQEAAACAS
>Sgl05743 UBD/UBC-like/UBD_UBC 62.5 0.0
MAAVDKYNLKNPAVKRILQEVKEMQSNPSDDFMSLPLEENIFEWQFAIRGPRETEFEGGV
YHGRIQLPADYPFKPPSFMLLTPNGRFETQTKICLSISNHHPEHWQPSWSVRTALVALIA
FMPTAPNGALGSLDYKKEERRDLAIKSREMPPKFGTAERQKVIDEIHAYMLSKAPPVPEN
LKQASAEHVGETEAEVETQTEGSENAGTSAATVEPENAGDERVVEEAQADGENVNPVIHR
EAIHRQVRTDIPNQQLQHRPAARVQKPGDDRLLTWAAVGLTIAIVFLLLKKLAKSSGYGA
LFLSES
>Sgl05763 E3_activity/RING/U-box 114.4 0.2
MRRHENSSKDRQTISQIIKIIKEISSSPECRNSSKRLYSNLVRRLKLLGPLFEELVDRQQ
QDDDDDVDDNDNEFVLSVDQVKGFDSLLNALISAQGLLKRVHESSKLFQAVQREKVSAEF
LHITGQIEEALSMISYDTLDLSEEVQEQIGLVHAQFLRAKARTESSDLQLEMDITKVQEE
AEPDAAVLQRLSHSLHLLTMDDLRKESRVFHEMVITSNSDLGDSFEKMSSLFKKLNDYLL
TLNPEIGMCDVDKGIIKHRSPVIPDDFRCAISLELMKDPVIVSTGQTYERSCIQKWLDAG
HKTCPKTQQTLLHTALTPNYVLKSLITLWCESNGVELPRLQGTSKTRRTGTSASSCDKAA
IGALLKKLAHGNIEEKRAAAGEFRLLGKRNADNRVCIAEAGAIPLLVELLSSSDSRTQEH
AVTALLNLSINDTNKGIIVSAGAIRDIVEVLNNGSMEARENAAATLFSLSVVDENKVAIG
AAGAIRALIALLVEGTPRGKKDAATAIFNLLIYQGNKIRAVRAGLVDPLMRFLKEVDGGM
VDETLAILAILASHPEGKTAIGQAKPIPLLVELIRTGSPRNRENASAILWTLCMGDVSNL
KMAKELKAEPVLKDLCENGTDRAKRKASSLIELLQRVEEPTD
>Sgl05775 UBD/UBC-like/UBD_UBC 112.8 0.0
MKLCPREVEKLALHNAGFLAQKRLASGLRLNYTEAVALIATQVVVHSEKFYNFRSSVFID
FEFCSCWKQECGGTDGHWKEASWKGPSETPYDGGVFQLAFAVPEQYPLQPPQVRFLTKIF
HPNVHFKTGEVCLDILKNAWSPAWTLQSVCRAIIALMAHPEPDSPLNCDSGNLLRSGDLR
GFQSMAKMYTRLAAMPKKG
>Sgl05807 E3_adaptor/Cullin_RING/DCX/DWD 86.9 19.1
MMFNKGNMALEKHFPASNLIANGKSLTFPLKIREKVALGDPEMSPETEADIDVDLREVYF
LIMHFLSGGPCQRTYGQFWNELLEHDLLPRRYHSWYSRSGVPSGDENDDGLSCPLSYNKL
VERYSHIDKDHLIKLLKQLLLSKVILPHGVATRNVPNAADVPTLLGAGSFSLLGYDENKG
DNAVHVQLQPVHMRWPHMRADQVRALRLREIGGGFARHHRAPSTRAACYTIAKPSTMVQK
MQNVKKMRGHRNAVYCAVFDRSGRFVITGSDDRLVKIWSMETAYCLASCRGHEGDITDLA
VTSNNAMVASSSNDCIIRTWRLPDGQPISVLRGHTGAVTAIAFSPRPSAVFQLLSSADDG
TCRLWDARYSQFKPRIYLPKPPDSVAGKSVTAPPIAGEQNYQIFCCAFNATGTVFVTGSS
DNLARVWNACKSGADDSEQPIHEMDVLSGHENDVNYVQFSGCAVTSRCSASDTFKEENFP
KFKNSWFGHDNIVTCSRDGSAIIWIPRSRKSHGRAGRWMRAYHLKVPPPPMPPQPPRGGP
RQRVPQTPRGVNMIVWSLDNRFVLAAIMDCRICVWNAADGSLVHCLTGHTESTYVLDVHP
FNPRIAMSAGYDGKTIIWDIWEGKPIRIYETGRFKLVDGKFSPDGTSIILSDDVGQLYIL
STGQGESQKDAKYDQFFLGDYRPLIRDTHGNVIDQETQIPPYRRNMQDLLCDSSMIPYPE
PYQSLYQQRRLGTLGIEWRPSSVRFAVGPDFSSDQDQILPLPDLDVLIDPLPDFMDVMEW
EPEVEVISDDTDSEFNVTESFGGDGRHISSTSSGNSECGEEDSEMECRNKDGVRRSRRKK
KRETEITTSSGRRVKRRNLDECEGSSHRVYQHKKSRAGRKRSRKKSSKASRPQRAAARNA
LTLFSKIKGTPDQDEYCSPDDSSESESELEDSNIESEESDRFALDERAKNLKGKEVVMDD
SVDVSGFKEFPENAWNKKRLILKFPVRDSSRALLSGSSIPTSGNLTDLAGSSSSASGGPV
EFDGKDSAQDRNGVLGNGNLCGYGRLGWLGGYGYNSMKWGGVRARTSKRTKFSEAQPLNA
SGSSCFSDNQVEADNVPCADLKPESEQSGGSGKLQEDAQLGHEHQGNSNGLTDANIELSA
LNRSVSSNEIEDEVHVAVENGALSSKSSDENNVSTWLSSATKKDTLDSDDPSEIKGECGE
GNERNGASSLEQRSGGEEVKEENQHQEADVDGGDCNGARKVDGTNANASFEISNSQVSHL
QKKDKMYSAVYKRSRSFKTRTSSDSNGGLIGENTSNVSCQNQNGNADTKGIMVDGIDQAH
PLEARDTTQDLVNPRRTAGRSRRTEKSSLKKFDRRSREEWGSSTTLGPRSTRNRRVNFVR
NASPVDRRKASQSQRKLSWLMLSVPDCSRYIPQQSDEVAYLRQGHQEYISSNNSYGRGPW
EQLRGEIRAVEFCKVIVLEYSIVPGSGESCCKMTLEFTDPNSSVYSKTFQLTLPEVSNFP
DFLVERTRYETAMERKWTRRDKCQVWWRNEGDGDGSWWEGRISEVKLQSLDFPDSPWEKY
VVRYKSDPTEEHSHSPWELHDPHDAQWEQPHLDDHTTKLLLSSLSKLLQSGNKPQDIYGV
QKLQQVSDKSNFLNRFPVPLSLEVIQLRLENNYYRSLEAVKHDINVMLSNAETYFLKQAE
FSKKIGRLSEWFEKKILSL
>Sgl05828 DUB/JAMM 31.8 2.2
MNVQPSTPAKPININTLTRKIDVDNRLSVGYYFRIADNLLKQAAVYREENNVVDLYVMLI
RFSSLVSETIPFHRDYQAYNPKERAHHKKKLMAVIDELETLKPEFQRLVDEHNKACTEMQ
QKQFHGREMTSYGSETSLVWPDVYDPSYESKQLQPANNKFQSSWKESYDFRAASTSTPIE
KKFSKLSFTVPLPNQETLSRHSFLGPNGLRRQWQGPSAEIKVSYPSHADLTPAEDLCLIQ
GIQNEARVQKDNSIGQDMEAVLSLDNGSWSRIQEDVPAEIIRQPVPPPVLAQIQPVSHPI
SPSRVADPRPGLAKPSEDGTQNPNSYQHLHIPVKMMEDFLRLAQQNTGRNLETCGVLAGS
LKNRVFHITTLIIPKQESTSDTCQTLNEEEIFEVQDSRSLFPLGWIHTHPTQTCFMSSVD
LHTHYSYQIMLPEAIAIVMAPTDSSSPHGIFHLSDPGGVSVIRNCQERGFHPHEEPSDGS
SLYEHCSHVYMNPKVRFDVVDLR
>Sgl05848 E3_adaptor/Cullin_RING/DCX/DWD 16.4 0.9
MQASKCTATIKYVTGLEFANFEVFITASGLSSMSLFMEDNERKIWDTVKGQLQTEFSDIV
SADETNLFAKQEKRGHLSIDYTCMKWVSFDRKKKRKLGTSLLVLGTGSGDVLALDVSAGQ
LKWKVNDCHPGGVSAISFASRGSCICTSGADGMVCELDPITGNLLRKFKASTKAVTSICV
SSVFCNGFNASWTHIYKGKPPLEQLTIPKSFFIRMEEIIVDSSTIRIFGIDAFVRRVLGL
VVVKKIVGVEFQLSSFRRVKVGWVLLERGRTDNVCGVVVLFKGDSEEEEMKNGVFKSHDG
KTIATAASQMKIFNSSDHKKIQKFTGHPGAVRCMIVSEDGKYVFSSAAGERYVAVWRVGG
SKMQSASCALAMEHPSVYLDCRYMNNSQADEAGLYVLAISEVGVCYFWYGKDTEELKKAK
PTRISLSAEDADSKNYKGVSAAIYAAKIQSAAEPATVSLFLAHGFLVKPSFEKVVVQYGE
DLQINVSRNGLLLPSSQPRKSKKQLELHAGATALDRANAEGALHPVPKVFDHDRIKQDQS
LKADYDQAVPIDTRADYNFPGVDATTCSMENRLKSLGIISDLKSTTPMKSSSLLKDIDLE
AMIPLKKMRAIIMSLSLVDALNILNVLVDKWLSRSCSGKYVLPWIYNILVHHGFQILSQE
PENATIYSLYKIAKSKGLASQSLLQISGRLQLVTAQIDKARQLKTQPSYMNNEMVESEDE
DEGVDEVHFGKEDESTTYNCGSTSKSTASPECVGGCEKEFGGMSTGKELLFVYGSGQWPV
GDILVS
>Sgl05860 E3_adaptor/Cullin_RING/DCX/DWD 85.8 5.9
MNCSISGEVPEEPVVSKKSGLLFEKRLIERHISDYGKCPVTGEPLTLDDVVAVKAGKIVK
PRPVQAASIPGMIGMFQNEWDSLMLSNFALEQQLHTARQELSHALYQHDAACRVIARIKK
ERDEARSLLAQIWAQNKKPMDMFEGEGNAAHATAISNGKRGAEEEDHGLVGKRARVGISN
DIIAELTDCNLELSQQRKKRTIPSTLAPIEDLERYTQISSYPLHKTNKPGILSVDIHFSK
DIVATGGIDTNAVLFDRSSGQIVSTLSGHSKKVTSIKIVPQDEGLVITGSADKTVRLWQG
SEDGNYDCRHVLKDHSAEVQAVTVHATNKYFVTASLDNSWCFYDLASGLCLSQVTDSSSS
EGYTSAAFHPDGLILGVGTTDAVVKIWDVKTQSNVAKFDGHTGPVTAMSFSENGYFLATA
AHDGVKLWDLRKLKNFRSFPSPDQDTPTNYVDFDHSGSYLTVASSDIRVYQVASVKSEWN
CLKTLPDLSGTGKATCAKFGPDAKYIAVGSLDRNLRIFGLPGDDGAQES
>Sgl05932 E3_activity/RING/RING 24 9.6
MGQQQSKDELLYQQVSYGNVEGIKTLHSEGVGLEYTDREGKTPLILACLNPALYDVAKTL
IELGANINAYRPGRNGGTPLHHAAKRGLENVVKLLLSHGANALLINDDCQTPLELARAKG
YSNVVRVIESHICLYSGWLRELYGPGFLELFAPQLLSRKVWVVVLPCGSRNLRKPFRLEL
AIYTNVQDAQPCTTIALWRATMEEPAFNQSNPSVTISEASIIRKHGKKRSCRPRRVSQTC
VKLVSLDENNKQQLQQFCSACKGIPQVMHPNFPFNHSTPFPPSTAPPAATEVPPVSKNTA
SPAADEDVELAMAIKASIQSAMEEGISVDHLRSPNDASSSSSTAAHSVSSNTQVDPPSKK
ASCSNQLVEEGETSVTSAITTNEPPTPMPAPSAPALTEEGFPEGPIHYPTIDSSMFATVE
TNHTNEDGSKRGESSSCVICFDAPVEGACVPCGHLAGCMSCLNEIKDKKWGCPVCRTNID
QVIKVFSV
>Sgl05934 E3_adaptor/Cullin_RING/DCX/DWD 84.4 12.9
MNVIALEVLMGCDVLCRYSHIDKDHLIKLLKQLLLSKVILPHGVATRNVPNAADVPTLLG
AGSFSLLGYDENKGDNAVHVQSQPVHMRWPHMRADQVRALRLREIGGGFARHNRAPSTRA
ACYTIAKPSTMVQKMQNVKKMRGHRNAVYCAVFDRSGRFVITGSDDRLVKIWSMETAYCL
ASCRGHEGDITDLAVTSNNAMVASSSNDCIIRTWRLPDGQPISVLRGHTGAVTAIAFSPR
PSAVFQLLSSADDGTCRLWDARYSQFKPRIYLPKPPDSVAGKSVTAPPIAGEQNYQIFCC
AFNATGTVFVTGSSDNLARVWNACKSGTDDSEQPIHEMDVLSGHENDVNYVQFSGCAVTS
RCSASDTFKEENFPKFKNSWFGHDNIVTCSRDGSAIIWIPRSRKSHGRAGRWMRAYHLKV
PPPPMPPQPPRGGPRQRVPQTPRGVNMIVWSLDNRFVLAAIMDSXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXAARRKFPSSISWAGRCLVKASSTFLPAMRRTIATGFDTSITE
DIWVTNERIKFKSDSSFHLDAMPMKVKDLMIDIGRWNSSLIWNIFDYKTAYSIIATQIDT
GRSVDGFSWRFSPIGQVTVKSAYFWFLNKSEHREEGSNFWKLLWNWNMPQKWKLLVWRIL
HRALPTGNDLIKRKVDVSGICHFCHSKRETLEHLFRDCEVTRKVWNCGPLGLIISSKDEF
RLDFWIKNIMVYGMKEDIASKQSNINNNFAATLWSIWLHRNSIIFNNAKCSPLCILQAQK
MYLGRWNIALQEINKGKRSKKLLDPKPHTCWEVGERDHSSPLWVLSTDGAWKTNEGKIKA
AAGWVIKKGDGSLHSKGHERVMANSALQAEALAMLLGIQNLQGFTTHVLVQTDCLQLVQA
ISNPDASPTCISVIVNSIIMLFSCFNYVKCVKVGRDAVSEPHCLAKNA
>Sgl05956 DUB/JAMM 31.4 2.2
MNVQPSTPAKPININTLTRKIDVDNRLSVGYYFRIADNLLKQAAVYREENNVVDLYVMLI
RFSSLVSETIPFHRDYQAYNPKERAHHKKKLMAVIDELETLKPEFQRLVDEHNKACTEMQ
QKQFHGREMTSYGSETSLVWPDVYDPSYESKQLQPANNKFQSSWKESYDFRAASTSTPIE
KKFSKLSFTVPLPNQETLSRHSFLGPNGLRRQWQGPSAEIKVSYPSHADLTPAEDLCLIQ
GIQNEARVQKDNSIGQDMEAVLSLDNGSWSRIQEDVPAEIIRQPVPPPVLAQIQPVSRPI
SPSRVADPRPGLAKPSEDGTQNPNSYQHLHIPVKMMEDFLRLAQQNTGRNLETCGVLAGS
LKNRVFHITTLIIPKQESTSDTCQTLNEEEIFEVQDSRSLFPLGWIHTHPTQTCFMSSVD
LHTHYSYQIMLPEAIAIVMAPTDSSSPHGIFHLSDPGGVSVIRNCQERGFHPHEEPSDGS
SLYEHCSHVYMNPKVRFDVVDLR
>Sgl05971 E3_adaptor/Cullin_RING/DCX/DWD 27.6 8.8
MGSSNIRDILTCFSPSLDFFAITSGDGRIKIWDTVKGQLQTEFSDIVSADETNLFAKPEK
RGHLSIDYTCMKWVSFDRKKKRKLGTSLLVLGTGSGDVLALDVSAGQLKWKVNDCHPGGV
SAISFASQGSCICTSGADGMVCELDPITGNLLRKFKASTKAVTSICVSSDGKTIATAASQ
MKIFNSSDHKKIQKFTGHPGAVRCMIVSEDGKYVFSSAAGERYVAVWRVGGSKMQSASCA
LAMEHPSVYLDCRYMNNSKADEAGLYVLAISEVGVCYFWYGKDTEELKKAKPTRISLSAE
DADSKNYKGVSAAIYAAKIQSAAEPATVSLFLAHGFLVKPSFEKVVVQYGEDLQINVSRN
GLLLPSSQPRKSKKQLELHAGATALDRANAEGALHPVPKVFDHDSIKQDQSLKADYDQAV
PIDTRADYNLPGVDATTCSMENRLKSLGIISDLKSTTPMKSSSLLKDIDLEAMIPLKKMR
AIIMSLSLVDALNILNVLVDKWLSRSCSGKYVLPWIYNILVHHGFQILSQEPENATIYSL
YKIAKSKGLASQSLLQISGRLQLVTAQIDKARQLKTQPSYMNNEMVESEDEEDEGVDEVH
FGKEDESTTYNCGSTSKSTASPECVCCWSSTAGVNDWTSSESYSSFVGPVAPVLQVGGFG
KEFGGMSTGQELLFVYGSGQWETFCSMLCQWTN
>Sgl05984 E3_adaptor/Cullin_RING/DCX/DWD 86.6 4.9
MNCSISGEVPEEPVVSKKSGLLFEKRLIERHISDYGKCPVTGEPLTLDDVVAVKAGKIVK
PRPVQAASIPGMIGMFQNEWDSLMLSNFALEQQLHTARQELSHALYQHDAACRVIARIKK
ERDEARSLLAQIWAQNKKPMDMFEGEGNAAHTTAISNGKRGAEEEDHGLVGKRARVGISN
DIIAELTDCNLELSQQRKKRTIPSTLAPIEDLERYTQISSYPLHKTNKPGILSVDIHFSK
DIVATGGIDTNAVLFDRPSGQIVSTLSGHSKKVTSIKIVPQDEGLVITGSADKTVRLWQG
SEDGNYDCRHVLKDHSAEVQAVTVHATNKYFVTASLDNSWCFYDLASGLCLSQVTDSSSS
EGYTSAAFHPDGLILGVGTTDAVVKIWDVKTQSNVAKFDGHTGPVTAMSFSENGYFLATA
AHDGVKLWDLRKLKNFRSFPSPDQDTPTNYVDFDHSGSYLTVASSDIRVYQVASVKSEWN
CLKTLPDLSGTGKATCAKFGPDAKYIAVGSLDRNLRIFGLPGDDGAQES
>Sgl06036 E3_activity/RING/RING 24.7 9.8
MKWGKYIYAQTKMVYSASLSTQKRLAGEIAESDAYVTMWKEFFKGRMTYLYRNEGQEMAP
TIPGQNETLLIRSFPCPSPEFRIKFNQVYVGDVVLLKNPMDSDKFVVRRLAALGGHKMES
TCEEDTPFVIDYDHCWVLADNQKLKVSEAKDSRTFGPVPIMDIMGRVIYRFQSMKDHGLV
KNSNKVLEEDSAVVRFELELNEMQKQQSKDELLYQQVSYGNVEGIKTLHSEGVGLEYTDR
EGKTPLILACLNPALYDVAKTLIELGANINAYRPGRNGGTPLHHAAKRGLENVVKLLLSH
GANALLINDDCQTPLELARAKGYSNVVRVIESHICLYSGWLRELYGPGFLELFAPQLLSR
KVWVVVLPCGSRNLRKPFRLELAIYTNVQDAQPCTTIALWRATMEEPAFNQSNPSVTISE
ASIIRKHGKKRSCRPRRVSQTCVKLASLDENNKQQLQQFCSACKGIPQVMHPNFPFNHST
PFPPSTAPPAATEVPPVSKNTASPAADEDVELAMAINASIQSAMEEGISVDHLRSPNDAS
SSSSTAAHSVSSNTQVDPPSKKASCSNQLVEEGETSVTSAITTNEPPTPMPAPSAPALTE
EGFPEGPIHYPTIDSSMFATVETNHTNEDGSKRGESSSCVICFDAPVEGACVPCGHMAGC
MSCLNEIKDKKWGCPVCRTNIDQVIKVFSV
>Sgl06044 E3_activity/RING/RING 24.7 9.8
MKWGKYIYAQTKMVYSASLSTQKRLAGEIAESDAYVTMWKEFFKGRMTYLYRNEGQEMAP
TIPGQNETLLIRSFPCPSPEFRIKFNQVYVGDVVLLKNPMDSDKFVVRRLAALGGHKMES
TCEEDTPFVIDYDHCWVLADNQKLKVSEAKDSRTFGPVPIMDIMGRVIYRFQSMKDHGLV
KNSNKVLEEDSAVVRFELELNEMQKQQSKDELLYQQVSYGNVEGIKTLHSEGVGLEYTDR
EGKTPLILACLNPALYDVAKTLIELGANINAYRPGRNGGTPLHHAAKRGLENVVKLLLSH
GANALLINDDCQTPLELARAKGYSNVVRVIESHICLYSGWLRELYGPGFLELFAPQLLSR
KVWVVVLPCGSRNLRKPFRLELAIYTNVQDAQPCTTIALWRATMEEPAFNQSNPSVTISE
ASIIRKHGKKRSCRPRRVSQTCVKLASLDENNKQQLQQFCSACKGIPQVMHPNFPFNHST
PFPPSTAPPAATEVPPVSKNTASPAADEDVELAMAINASIQSAMEEGISVDHLRSPNDAS
SSSSTAAHSVSSNTQVDPPSKKASCSNQLVEEGETSVTSAITTNEPPTPMPAPSAPALTE
EGFPEGPIHYPTIDSSMFATVETNHTNEDGSKRGESSSCVICFDAPVEGACVPCGHMAGC
MSCLNEIKDKKWGCPVCRTNIDQVIKVFSV
>Sgl06070 E3_activity/RING/RING 34.6 8.0
MDNSPPSPSPPPPFQLPLLHSPKTSNFPVIAIVVIGILATAFLLISYYIFVIKCCLTWHR
VDIFNRFFSRVRDPSDEDGVSIATNNLLVNIGVEKKGLDEALIRSIPVIQFRKLADGRNL
NDETLEAGGGSYECAVCLSEFEEGERLRVIPNCCHAFHIDCIDVWLQSNANCPLCRSAIS
PSSILYNHHHHLVQLPQKEEDNNGCGRDNNDNDNDNDDDDDYVVIEIEGNNLDEPTLVTR
ESSAEKKKLRHVWSIGDELIDMRRKKDEEFQNIQPIRRSISMDLSSDREFCLEIQRFSKS
KEIEVSCSSGSSCNYSTKVRRSIFSFGYGRGSRCSVHLDP
>Sgl06124 E3_activity/RING/RING 33.7 8.1
MDNSPPSPSPPPPFQLPLLHSPKTSNFPVIAIVVIGILATAFLLISYYIFVIKCCLTWHR
VDIFNRFFSRVRDPSDEDGVSIATNNLLNIGVEKKGLDEALIRSIPVIQFRKLADGRNLN
DETLEAGGGSYECAVCLSEFEEGERLRIIPNCCHAFHIDCIDVWLQSNANCPLCRSAISP
SSILYNHHHLVQLPQKEEDNNGCGRDNNDNDNDDDDDDDYVVIEIEGNNLDEPTLVRREQ
SAEKKKLRHVWSIGDELIDMRRKKDEEFQNIQPIRRSISMDLSSDREFCLEIQRFSKSKE
IEVSCSSGSSCNYSTKVRRSIFSFGYGRGSRCSVHLDP
>Sgl06185 E3_activity/RING/RING 36.5 8.6
MVRLKPYAGLSLFATIAVFYHAFHSRKQFYPAMVYLSTSKISLVILLNMGLVILCSLWQL
AKRLFLGRLREAEVERLNEQSWREVMEILFAITIFRQDFSVSFLAMVTTLLLIKSLHWLA
QKRVEFIETTPAVPTLSHVRIVSFMGFLLLLDSIFLYSSLKSLIETQQASVSIFFSFEYM
ILATTTVAMFMKYIFYVSDMLMEGQWEKKAVCTFYLELIRDLLHLSMYLCFFMVIFMNYG
VPLHLIRELYETFRNFKIRIADFIRYRKITSNMNDRFPDATPEELDSSDVTCIICREEMT
TAKKLRCGHLFHVHCLRSWLERQNTCPTCRALVLPPETGTTTAGGQPGVSQSGTHQPAST
STPGQGSNGGTESTLSGNQARLQAAAAAAAIYERSIVYPSANTLMWSPGYAVLPQVYGAV
PGANNATSDEVQGLVGQFQHQQVISSGQMSYPYAQSPPFAVSSIQVPGTDMLREGNSQSS
MDSERNALEQRIQILQNQLNGLRKQQLDKGASSSYSASTVSNVQTAESISDATSHTNTQE
AN
>Sgl06198 E3_adaptor/Cullin_RING/DCX/DWD 93 15.9
MDPRNAFQEISLTRKNSKENLDRFIPNRSAMDFDYAHYMLTEGKKGKENPAASSPSKEAY
QKQLREVFNMNRPRILAFKNKPPTPVEFMPQEYAAVQQSKPVKPRRHIPQTSERTLDAPD
LMDDYYLNLLDWGSSNVLAIALGTTVYLWDASTGSTSELVTVDDDKGPVTSVNWAPDGRH
IAVGLNNAEVQLWDSTANRQLRTLKGGHRARVGSLAWNNHILTTGSMDGKIMNNDVRIRD
HVVETYRGHQQEVCGLKWSASGQQLASGGNDNILHIWDRSQASSNSATQWLHRLEDHTAA
VKALAWCPFQGNLLASGGGGGDRCIKFWNTHTGACLNSVDTGSQVCSLLWSKNERELLSS
HGFTQNQLTLWKYPSMVKMAELTGHTSRVLFMAQSPDGCTVASAAGDETLRFWNVFGTPE
VAKPAPKAAPEPFAHVNRIR
>Sgl06260 E3_adaptor/Cullin_RING/SCF/F-box 16.3 0.0
MKKRKFSQKNKSPKNDCCLPELPPELISEILARTPVKPLLKFRCVCKSWRSLIDSNDFVS
LHRKLYSTSFSDTRILVFQQRQRSYDYILTVRHSDTFKKVGDEVGKFPFTFWIFESCNGL
LLIEHEDTFKIWNPFIRKCLTIPLCPIDKPGCLLWYRLGFAASTNDYKVVVIDIQTGKIA
VYSVNDHCWQVKTNGINFDEGGFGVPLFHDCPTPIVFPDARAFYLVLCNNQNESKVIFSY
DYDTEKSKFIQLPDAVSVNDGNKLWFLFRFGESIAIFIMSSNNDYEYDIWVMEDDHEESK
ETWKLKASRKMNLKADKLFKSVITGYENSSNFMVLFNYIQQNDSFVMVKSSRFKFTDKLM
SYNLTSQEIKQLGKSLCGKISFDKYVESLALHRGVEGQTLVSFP
>Sgl06286 E3_adaptor/Cullin_RING/DCX/DWD 59 5.2
MDNSSNKNLVTYDSPYPLYAMSFSHRSSDQLIAVGSFIEEFNNRVDVLTFDNETLSLNLS
PNLSFAHPYPPTKLMFQPPSSSSSSTSSLPILASSADCLRLYSFKNDSIELVSSLNNSKS
SEFCAPLTSFDWNDFAPQRIGTSSIDTTCTIWDIEKGVVETQLIAHDKEVYDIAWGEAGV
FASVSADGSVRIFDLRDKEHSTIVYESPEPDTPLLRLAWNKQDLSYMATTLMDSNKVVIL
DIRSPTMPVAELERHQLSVNAVAWAPQSGRHICSAGDDGQALIWELPAVVGPNGIDPLTV
YNAGSEINQLQWSSAQPEWIGVTFSNKLQLLRV
>Sgl06296 E3_adaptor/Cullin_RING/SCF/F-box 16.9 0.0
MQINNLPDGLLIEILGRLPCHVVLRCKTVCKHWLSLISDPFFIRTFIHLQETVNQSSTFT
LVHQFYYWHHHITESASRTVQAISEHPVVQSRGLLLDFVPCFQQFDPWPIRIVASNRDLV
VCHDNKMFSHQSMYYVCNLLTKQWRALPPIPSRHVEDDMATGLVTYGEDDLPVSKYKVVR
ILKIGSYSNHLIAEIYCSDTGEWTESLLWCPQNIRRFWQFRTSAVTVNNALHWIINGNNG
ETIIVLDPFRGSNGECRLIDPPLELKFEMAHVCLGMCRGKLRVSTIKGVHPNRMLKVWEL
QDYDNSKWLLKNRICLKEMVFVGDCEFDLLEFSTNLVLSFHPVDENVVYLRCHNHIMRCN
MKNGTLEVVSKCLGDPTFVIRTLTVFPLLHPCWPSSVHCQSPKRASLEPFSG
>Sgl06297 E3_adaptor/Cullin_RING/SCF/F-box 19.4 0.0
MGKLSTSHRPLSIPSSSTDACNNINNILVDSLLIEILQRLPCISVLQAKSVCKHWYLLLS
DSHFVQTFTRYHDHHTLPFTLVYEFHLWHRHLTNNLRHIIHIVSKHEVFKSRGFHLDFLP
CLQSWESHPIWLVGSYKDLLVCCHLKMSLLQGVYYVCNPLTKQWLGLPPAPGHHRLADTA
IGFITSEKLVCQNTFMLVQIPELDSCRCNGNCFKVNMFCSEVGEWRTYEVTSARSFARTW
QFRPDSVVFKNKFHWLVNSENIVVLDPSELTKGTCQVVDLPTELNPDIGICLGYCQDYLT
VCQITRGCFNCVLVVWKLRDYATGKWDLEGKINLKEMVLVKNIQLFEFRFSTMEVLAFHP
SDVGILYLRFDNQIVICNVGRRTLKVVSEYLQDSSFSVGTCGVFLLMHPCWPSQIPSLPN
>Sgl06301 E3_adaptor/Cullin_RING/DCX/DWD 34.1 16.8
MSTPFQVASLTNPPTFPNAVVWSDDNLIAVATADIVTILNPEHPQTPRGVITLTPSEPFQ
IGVIDRTDLLSGCLLPTCLSRDRQTVFARFHGHLLGSLLIMGIHKCLLAVCSAEGRVKVY
RQPYCEFQAEWIEAMDISVLLHEYYAKINYREPQAPSSAGFDDSSGQTRTKTYIAADKTN
TMTLRKHHKRKRDKDFNYLEEIDTSNAESLCVKAVAEPVYIQSSTMQEGSSVEVFKMDGG
QNVWIAGKLQRVEGSMALVHFCETDSSGEPKWRKMGFESDMHNQPKNTGVSTNDGDCGLP
EIRPSMELGRLSEQILLAELSEVDQFLKAGQLVEAWSRDRWVEGVFVSFSNGGLSVKFSG
DAEAVALNPTDVRLAPLWIAEKKSWKVTVVQCHVQDSPEVAVKKSDLGDLNYSSESDTEL
DILTRDGRNSSKRTTANSTKKKLTARQYSSRSSMLASLVVAWSSHLQLSATNSEKVLDCY
CLLAVGTKSGSISIWRFERPSYYSVERSDNSVSMSFIGVIQAHDTWVTALSWGFLTSDAR
TQVLLATGCCDGSVRIWHAHVCDLKNVSETDQNPFSLVSEVTAGDNVLVSVVSLCVPIQS
PQKILLAIGKGSGSFEVWTCDTKFKSSHNVGSYDAHVQAITGLVWAFDGRCLYSCSQDNS
IHGWMYHKGSLSEASVPPNNLGTRSFSDLPSVSDSCYGMALSPGNLALAVARRFDAGQLD
NMYQKRTQRAAVEFFWIGGQQVELPTTANLELDVEGYSSFSKEELGYWGSKLLWSLNQFE
CHNKHLVIWDIVAAMLAFKPCAPWFIKHLAFRWVELLLKNHLDPSIKDIFSDMPKHLSKI
SSRQLHLLNILCRRVIAPSGFEAVKVYAKAAALSKSCGEEEQQWMDIVLNSEKELRERLV
GLSLSTVLVCMSDEASKAESGLWNPVGVAQMVKWVILNKDHLSCQLSPLASKIEEFGTRL
QSACDYNTEEQCSFCSAAISFESAEIASCEGVKISGQEPAQQHKLTRCAVSMKVCPLTAI
WFCMCCRRRASNLPPLQLFTMNKYPSDFLSFTKSLTANLLPNPLCPFCGISLQRLQPDFL
LSLSPV
>Sgl06308 E3_adaptor/Cullin_RING/DCX/DWD 43.3 17.7
MSTPFQVASLTNPPTFPNAVVWSDDNLIAVATADIVTILNPEHPQTPRGVITLTPSEPFQ
IGVIDRTDLLSGCLLPTCLSRDRQPCVRSLSWSPAGFTSHNGCLLAVCSAEGRVKVYRQP
YCEFQAEWIEAMDISVLLHEYYAKINYREPQAPSSAGFDDSSGQTRTKTYIAADKTNTMT
LRKHHKRKRDKDFNYLEEIDTSNAESLCVKAVAEPVYIQSSTMQEGSSVEVFKMDGGQNV
WIAGKLQRVEGSMALVHFCETDSSGEPKWRKMDFESDMHNQPKNTGVSTNDGDCSLPEIR
PSMELGRLSEQILLAELSEVDQFLKAGQLVEAWSRDRWVEGVFVSFSNGGLSVKFSGDAE
AVALNPTDVRLAPLWIAEKKSWKVTVVQCLVQDSPEVAVKKSDLGDLNYSSESDTELDIL
TRDGRNSSKRTTANSTKKKLTARQYSSRSSMLASLVVAWSSHLQLSATNSEKVLDCYCLL
AVGTKSGSISIWRFERPSYYSVEHSDNSVSMSFIGVIQAHDTWVTALSWGFLTSDARTQV
LLATGCCDGSVRIWRAHVCDLKNVSETDQNPFSLVSEVTAGDNVLVSVVSLCVPIQSPQK
ILLAIGKGSGSFEVWMCDTKFKNSHNVGSYDAHVQAITGLVWAFDGRCLYSCSQDNSIHG
WMYHKGSLSKASVPPNNLGTRSFSDLPSVSDSCYGMALSPGNLALAVARRFDAGQLDNMY
QKRTQRAAVEFFWIGGQQVELPTTANLELDVEGYSSFSKEELGYWGSKLLWSLNQFECHN
KHLVIWDIVAAMLAFKPCAPWFIKHLAFRWVELLLKNHLDPSIKDIFSDMPKHLSKISSR
QLHLLNILCRRVIAPSGFEAVKVYAKAAALSKSCGEEELQWMDIVLNSEKELRERLVGLS
LSTVLVRMSDEASKAESGLWNPVGVAQMVKWVILKKDHLSCQLSPLASKIEEFGTRLQSA
CDYNTEEQCSFCSAAISFESAEIASCEGVKISGQEPAQQHKLTRCAVSMKVCPLTAIWFC
MCCRRRASNLPPLQLFIMNKYPSDFLSFTKPLTANLLPNPLCPFCGISLQRLQPDFLLSL
SPV
>Sgl06330 ULD/UDP/UBQ/UBQ_PIM 97 0.3
MQIFVKTLTGKTITLEVESSDTIDNVKTKIQDKEGIPPDQQRLIFAGKQLEDGRTLADYN
IQKESTLHLVLRLRGGIIEPSLMALARKFNQDKMICRKCYARLHPRAVNCRKKKCGHSNQ
LRPKKKIK
>Sgl06331 ULD/UDP/UBQ/UBQ_PIM 97 0.3
MQIFVKTLTGKTITLEVESSDTIDNVKTKIQDKEGIPPDQQRLIFAGKQLEDGRTLADYN
IQKESTLHLVLRLRGGIIEPSLMALARKFNQDKMICRKCYARLHPRAVNCRKKKCGHSNQ
LRPKKKIK
>Sgl06358 E3_adaptor/Cullin_RING/SCF/F-box 19.8 0.0
MEGLPAELCLKVFCLLDYQNLSIAQQVCRKWNNLGADNVLWAKLFKARWGEDRAVLHNAD
CSKSWKAAYEVQDRCDRVGLEYKIIREGVDYYLIYHGEIQRHLGSRIQKRKTEDTKSFSR
QSGENGVAMQEGSLIGGTSYGILERILFFIGDLEVASSEAKRSRLM
>Sgl06366 E3_adaptor/Cullin_RING/DCX/DWD 85.2 12.4
MLKQTMDTCSDPGEFQFFDALEEIADSGVECPDSICSNSARGLSDSVSSSAQFDVWIQNL
ESVEARRSKFFNWLGVDVSRTSGDDSEEGCDSELGRDRIATVNDSVLKKTRFECEFSSIR
SEHHVSFCSVDDTEFSGNLSPKENLSGGMKDNVGDENREPGANLRVRTEDSVRSSSSSSS
EGYSPVKNTARSCSVGPTKKVKKWWLNRLRSFNCVMEGGQSPCNCDSSARRKIQRVKVHQ
SKTQSKELSALYYGQNIQAHKGAILTMKFSPDGRFLASAGEDKVVRVWQVVEDDRSNEID
IPDMDPSCVYFTMNNSSELKPVSNDKEKNGKLRRNSDSACVVIPPKVFRISGKPVHEFQG
HTSEVLDLSWSKNDCLLSASVDKTVRLWQVGYGRCLQVFPHNNYVTCVQFNPVDDNCFIS
GSIDGKVRIWEISQKKVVNWTETKDIVTAVCYRPDGQGGIIGSIAGSCRFYSISDNQLEL
DAQIYLHNKKKSSGKRITGFQFFPQDPNKVMISCADSQVRILQGVNVIGKYKGLRRTGAY
CTAFFTADGKHIVGASEDSNVYIWKCNDQDFSNSSSSIKKIKSSERFLSNASVALPWPGL
QNESNRNQWHDGAFNGLPHGSRPFFSPPHFSCRQDFFLELYYPKGSALWPEEKLVSSSSP
SLTSSMHKSEYKFLKTCQNRSDSDAWGMVIVTAGWDGRIRSFHNYGLPVPH
>Sgl06414 ULD/UDP/UBQ/UBQ_PIM 100.5 0.5
MSMASVALSPLRKESLNIPTFLSDRHDCLMNESILIYLTVGGSVLPIPVLESDSVASVKL
RIQNHKGFFVKNQKLVFDGRELARNDSCVRDYGVANGTVLHLVLRLSNIQAITVRTVCGK
ELEFHVERSRNVGYLKQQIAEKGKGFFDRKDQELICDGEELQDQCQIQKYCKNSDAVIHL
LVQKSAKVRTKPVEKDFEVLIVASDQNEKEVDEIVKDGCEWGIEPVHPFGPLNKQFCRDI
VFEQLIINPKIELPLVIKQLINSTFSGLDRGNRPVRSSEGCGGAYLMLDPAGEEYISVFK
PVDEEPMAVNNPQGLPESKDGEGLKKGTQVGKGALREVAAYILDHPRTGPRSPYHAEIGF
AGVPPTALVKSLHEGFYHPNGYTGSLKNLKIGSLQMYMKNSGSCEDIGPGDFPVEEVHKI
SVLDIRLANADRHAGNILVSRDDEGQIMLIPIDHGYCLPSKFEDCTFDWLYWRQARKPYS
SETIKYIESLDAEEDISLLKLHGWDIPSECARVFRISTLLLKKGVARGLTPFAIGSIMCR
ETLKKESVIEQIVQEAEEALLPESSETAFLETVSTVMDRWLDELSA
>Sgl06427 E3_activity/RING/PHD 35.6 20.3
MIIKRSLKSTMPTLKRCRVIQSSNTEDEDSNDRKKRKYNSYNNGGTNSSNNSSSNYFPLS
LLGEVAAGVIPFSGFHRIFSANNNDNADFRGFASSWCSDVSCSPAEEEDDDDDEEEEEEE
EEEEGGRRGRMSKVKTRHVAEVAKESPRPPLVRTSRGRAQVLPSRFNDSILDDWKKEKTS
KMNNSNNFNGNNASSGECSDEYDDNGDYVSVRKNEKFGFKAMKGKVSGRCNVHRFEDETY
GVSTSTEEVGYENGFNDDNEEEEIGWKGRRSTNHDVRRYSSSRSTITSLRDRRHWLEYEK
TGDDWHGNNKRLMVNQRRNSREVGMDGFVPGDVVWVKSGKNDPLWPAIVINPASQAPRQI
LAFRVPRAVCVMFFGYSKSREQRDYAWVKHEKIFSFADNVDRFQEQTCLNGSSLSNFHKA
LEEAFLAENGFLETLMQEINKTARSASCTNSVSRRAHEATGSHQGQEFHHYSQNGIKKAK
DTTLCAGCGAGLPLKMKKTGKASGSEGHFYCTSCAKSLRLKQYCGICKKIGNHSDSGKWV
RCDGCKIWVHAECDRISSNLFKDLGATDYYCPDCRVKFNFELSDSETQPRIKCNQNSDQV
KLPDKVNVICSDMEGIYFPSLHLVVCKCGYCGTEKQQLSEWERHTGSNVKNWKKSIRVKG
SMLTLEQWMLQMAEFHAQAAASTKPPKKPTLKVRKQKLLSFLQEKYEPVYAKWTTERCAV
CRWVEDWDYNKIIICNRCQIAVHQECYGARNVRDLTSWVCRVCETPDIERECCLCPVKGG
ALKPTDIDTLWVHVTCAWFRPEVSFASDEEMEPAMGILSIPSSAFVKVCIICNRYMVPVP
SVVSAQLIIMLCVHQGLATVWSSVHLLIMIEFGDLWH
>Sgl06436 E3_adaptor/Cullin_RING/SCF/F-box 14.2 0.0
MIRSTKKHRKRKKQRLKNDNNELQNDNVLPLIIPSIPRDVELPEELIFSEILTRLPVNSL
TRFKSVSKRWNFLISTPHFIKSHIKCTNSNPFVPTNCVFIKSDYYFYILNYAAYDKTPDD
SFGEKGLTVVKSGKFSDNGVNTFLIGSCNGLVCFGRGSGFTSDYYFYVYNPLMGQFLHVF
DPLGNFQGKLIYGFGYVSCKDDYLMFVGGLQRRSCDNFVYVYSLKSDDWKKIGEFDVDGF
SIFLGGRGVLVDETLHWDTSQVRVSDSKYICGFDLVDETFKDVRMPRLFWDDDHNLDFKV
CEMGGSLCVWAEDVYGEVEMWSLRQYGVWDSWTKLFKIDMIFAVSNFYGCLENGKVLVQT
EDGSLLLVDPDQNPPEFTSLVKDLGDIEVLSYIRSPVSPFLHLHVPEMEGQTQVSYE
>Sgl06440 E3_adaptor/Cullin_RING/SCF/F-box 18.9 0.0
MISFKYEDDPFLGLPKELVLDILYRLPVKSLGRCKAVCKSWLSLISDPEFAISHLDYWNS
NYQPLTLISQKYNILSTLELCDPTDITDGVTLAKLNHQFLDDGDVSDSCYCFIVGSSDGL
ICIYVKQMEERRRGQDSMHLWNPCTTEEIEISLPVKWGSFYVYINSSWFGCVPSSDDYKI
FLVYSEWRPFQKSMYLYSLRSGRWRRVHVSDDDLLSISGVNSVFFEEALHYLISGKWIVI
FDLVTETFKKVPFSIKPDQVSEYNDLLLGVIGEYDRLCAMFIHYLSDEWVIELWTLEEYN
NWNSWIKLYQIELQEDIISNCNQFLGFTYSGYLCMQHENGLVLLDRDDDPPSHVVARNQS
FAKAYKVMDYVESLVSPISIP
>Sgl06451 E3_activity/RING/RING 35.1 4.8
MNYTRAHIQAQSLLCSRRNVNIEEILLKKPYPSVCPMLCSKIDKNISSSSSSQDTRSNPT
NHGVFRSRRLSRIRATTTTVEMPSSGDQMECHHNQKLLLNYVPVFVMLPLGVISTNNSFI
DEKGTRKQLEQLKLAEVDGIMVDVWWGIVESEGPMRYDWQAYRRLFKVVLEYDLKIQAIM
SFHQCGGNIGDIVNIPLPQWVLDTGKTNPDIFYTNQAGTRNVEYISLGVDNEPVFEGRTA
IQIYSDFMRSFRENMSDFLEDGVIIDIEVGTGPAGELRYPSYPQNQGWTFPGIGEFQCYD
KYMKEDFENAAKEAGYPNWELPSNAGQYNDSPEETEFFRKNGTYKTDQGIFFLTWYSNKL
IFHGDQILEEANKAFRGCSLKLAIKVSGTHWWYKYHCHAAELTAGYYNLDHRDGYRPIAR
MLTRHNAIFNFTCLEMKDTEQQSAEAYCGPQQLVQQVFSDAWKEKIKVAGENALPRYDNT
AYNQILLNARPNGVNETGEPTLKMFGFTYLRVSDDLLEKSNYKRFKKFVKRMHANQKYCP
KPEEYGNYIEPLAPSKPRIPIDDLLDATIPTEPFPFDEKTDTSVDDSLFSAFINFPCNKA
TSTNCSISKCGDSSGGNTPAIRFPFRIKSPGQEPSSCGRSGFDVWCDERSKHTLIELPRS
GNFKVKSIDYAAQEMWVNDPNKCLPKRLLTFNILDSSPFGEVYHQDFSFFNCSNTLNNTS
INNNDDDDTNFTHLKGLLIVGPIKCLSGSNHFVYAMPTNGTTFTNHTSNLLSPLNCSLVA
PLIKVPVQWPPSLHNDHTVLSLLADLHGDLRLSWYIPECRPCELNGQMCALETASNDSDV
IICSDIPNEGIAGKLPLTTFIAVILVICAPSIICIVGSIVIWIRHCYKHRRSNRNTQTGP
VDSNGPTVNEELGQLAEVNIEFARHIVRMGLNEEANLDRRPTVVISEMEEVGLGQGPNRE
NDNMCAICMGEYRRKDRIGTLPSCEHYFHANCINKWLLSRGRFGKTCPICRAPVDSS
>Sgl06452 E3_activity/RING/RING 38.7 6.4
MILLDILSLMPMACILCLLSCLNTACHHEADSEILITLRPALSYCSKTMPKGDDDQQCSI
CLDDYEDGDMVEFLDCFHLFHAHCIDQWLPLSQTCPICRLQC
>Sgl06454 E3_activity/RING/RING 32.8 4.6
MDSAGNNPPTPSDDGSHTAVKWLGIVGAIAIGLILIRLCWIWCKWWHLQSRRRNNNNNNV
VIDLTYDNSPSPTNEPREVSGLNQLIIDSYPTVLIGKSGSAIKPHEATCSICLGDYVPGD
TIKIVPECIHRFHAECLDLWLINNITCPVCRIPPQNISSVV
>Sgl06455 E3_activity/RING/RING 33.2 8.6
MISKATVEGLKERIGYSSAFGVSSVGKSGGLCLFWQEDIVDFSLVSFSQNHICGDMRMGE
EAWRFVGMYGWPDSSAKHKTWDLICDLTRNSPLPILLGGDFNEILSWDEKEGGVIGARRE
IDQFREALNVCELRDLGFEGQWWTWERGKTVETCVRERLDRFLASSAWCRLFPNARVEHL
LRYRSDHAPIVIRLKYKKKRGRGRSKSFKFETAWLLDDSCKAEVKASWDRASGCALEDKL
LRVGGSLSSWSKEKFKDIDGKIEKAERDLRDCQSQGINQERCELQAKIEEQLNDLYEKQE
ALWHLRSRVQEIREGDRNTSYFHHKASQRRKRNMISGLYDKEGILQEDEECMEALIADYY
TTIFSTSSPDASVTEEVLSLIPQCVTAVQNSNLLQPVSSSSTECCETMYCNNITSHGNKI
EFPYRLRGEQPESCGCHGFDLYCDDELGLLLELPHAGNFTVEYIYYSTRKIRISDPNECL
PQKLLTVDLSTTPFRGEEESVDYHVYNCSGVGDELDSYGEKIDCLSGSNYTIISDSSNKR
VDDLNILKCLFIKHVSIPFYLPSTYMANAKHPFRVTESCGCQGFDLYCDDEFGLLMEFPN
AGNFTVDYIFQYSEREIQLSDPNNCLPQRLLAGLNLSMTPFRLTRSVDFQLYNCSGVDYP
MDSDYVEKIDCLSDADFDYSFLSIYSTIDLTWDEHDECISCVLAKEKRSGGRDSYSKVAI
VVFIVGITVPVSFVILFVICLCCRRGETPRNQSAINTNADASTNTSATASSGLDQVTINS
FPTVILGEHGGLTNKSEHDTCPICLSEYSPKDVLKMLPHCLHRFHADCIDMWLKSQPTCP
VCRTSPTLRFTDCV
>Sgl06459 E3_activity/RING/RING 35.4 5.9
MVMFDGRILPFAVVFSIMLLIYILCKMGWRKRGEAQLPVYVTEAQDQTQGQAQAQAQSQS
QVQEEPKKGLDQETIDSYPTVVIGKNMLMKLDDNMCSICLSEYRQNDVLKVLPECLHRFH
SDCLVEWLKLNATCPVCRTHPPRLNPTAS
>Sgl06461 E3_activity/RING/RING 33.1 17.3
MNRHNHQASYVFDIAPSPRRGGATTSSQSHSPPPAAVGTIGLDEVTIDSFPSMIIGESGR
MIKKDDNSCPICLSDYTPKEKLKMLPLCLHRNNVFTFSPKMHFLKNYTIFFLLCVLLPTS
TKCNENGSKLSDFCITQVCSYREPVTRYVQFPFLIRNESLPQSCGYPGFDLLCDGDYRLL
INLPNSGVFSVEEIDYVNQELWLNDPDDCLPKKLISLNGSNYVSKSPFNPVLEQDYWFYN
CTNDFFNSSDDEISVIQCLSGENYRVFATTMENIVKGKNSSFCGKIGPIKVPVRKRSFEM
YSSLELENDILLTWTKLRECGECYQKNGKCRFKRGSGLEVGCFNLPRRGLSRSAMFAIAV
AFVTPLVLVTCCFAYFILKAIWYRRRTNRARLPSFAELALAVTPQPERVIQGLDQTTIES
YPKVVLGESRRLPKPDDKSCAICLGEYLAKETIKTIPDCGHCFHDHCIDEWLLLNATCPL
CRNSPSKTPQSNA
>Sgl06462 E3_activity/RING/RING 32.3 8.8
MSDHCSIQVCKSDDPISRYVQFPFLIKNESMPSFCGYPGFDLFCNEDDKLTIKLPNLGAF
LVEEIDYVNQELRLFNDLDHCLQKKLLSQNGSIFVGKSQFLPIIEQDYWFFNCSNDFFNY
SNVEPIECISSTSYGVFATNVEKISESNSSMCQKIGPIKVPKGVNERNPSSILSGDFRLN
WYHPRECVTCHEKKGRCRFKGNSNLDVECFFPGRGLTRNAMVAIGLAFTAPLALITFIIV
YFVIKSVTNGQGRAGNRGEGVTLTPQPQNAGHGLGLDHDVIESYPKVVLGESRRLPKADD
VHCPICLGEYVAKESLRTIPDCGHCFHAECVDEWLHLNASCPICRKYPSKPPQIDDT
>Sgl06504 E3_activity/RING/PHD 35.3 20.3
MKGKVSGRCNVHRFEDETYGVSTSTEEVGYGNGFNDDNEEEEIGWKGRRSTNHDVRRYSS
SRSTITSLRDRRHWLEFEKTGGDWHGNDKRLMVNQRRNSREVGMDGFVPGDVVWVKSGKN
DPLWPAIVINPASQAPRQILAFRVPRAVCVMFFGYSKSREQRDYAWVKHEKFQEQACLNG
SSLSNFHKALEEAFLAENGFLETLMQEINRQLEVLLALILSLEEHMRPLVHIRVKNSTII
NGIKKAKDTTLCAGCGAGLPLKMKKTGKASGSEGHFYCTSCAKSLRLKQYCGICKKIGNH
SDSGKWVRCDGCKIWVHAECDRISSNLFKDLGATDYYCPDCRVKFNFELSDSETQPRIKC
NQNSDQVKLPDKVNVICSDMEGIYFPSLHLVVCKCGYCGTEKQQLSEWERHTGSNVKNWK
KSIRVKGSMLTLEQWMLQMAEFHAQAAASTKPPKKPTLKVRKQKLLSFLQEKYEPVYAKW
TTERCAVCRWVEDWDYNKIIICNRCQIAVHQECYGARNVRDLTSWVCRVCETPDIERECC
LCPVKGGALKPTDIDTLWVHVTCAWFRPEVSFASDEEMEPAMGILSIPSSAFVKVCIICK
QIHGACTQCCKCSTYYHAMCASRAGYRMEVLFSFFSFGLLLLNFVSNLIVKVALLGKSGK
QITKMVSYCAFHRAPNPDTVLIVQTPSGVFSAKNLLQSKKRTGSRLISSTRSVPEEASTQ
EVSEADPDSAARCRIYIRPKNKNCKRKGEEAVAHHVRRPCHHSLREMERVNAFRIVEEPK
TFSTFRERLYHLQRTENDRVCFGRSGIHGWGLFARRDIQEGEMVLEYRGEQVRRSIADLR
EARYRIEGKDCYLFKISEEVVVDATDKGNIARLINHSCMPNCYARIMSVGDDESRIVLIA
KTTVPAGDELTYDYLFDPDEPDEFKVPCLCKAPSCRKFMN
>Sgl06516 E3_adaptor/Cullin_RING/SCF/F-box 14.2 0.0
MIRSTKKHRKRKKQRLKNDNNELQNDNVLPLIIPSIPRDVELPEELIFSEILTRLPVNSL
TRFKSVSKRWNFLISTPHFIKSHIKCTNSNPFVPTNCVFIKSDYYFYILNYAAYDKTPDD
SFGEKGLTVVKSGKFSDNGVNTFLIGSCNGLVCFGRGSGFTSDYYFYVYNPLMGQFLHVF
DPLGNFQGKLIYGFGYVSCKDDYLMFVGGLQRRSCDNFVYVYSLKSDDWKKIGEFDVDGF
SIFLGGRGVLVDETLHWDTSQVRVSDSKYICGFDLVDETFKDVRMPRLFWDDDHNLDFKV
CEMGGSLCVWAEDVYGEVEMWSLRQYGVWDSWTKLFKIDMIFAVSNFYGCLENGKVLVQT
EDGSLLLVDPDQNPPEFTSLVKDLGDIEVLSYIRSPVSPFLHLHVPEMEGQTQVSYE
>Sgl06520 E3_adaptor/Cullin_RING/SCF/F-box 18.9 0.0
MISFKYEDDPFLGLPKELVLDILYRLPVKSLGRCKAVCKSWLSLISDPEFAISHLDYWNS
NYQPLTLISQKYNILSTLELCDPTDITDGVTLAKLNHQFLDDGDVSDSCYCFIVGSSDGL
ICIYVKQMEERRRGQDSMHLWNPCTTEEIEISLPVKWGSFYVYINSSWFGCVPSSDDYKI
FLVYSEWRPFQKSMYLYSLRSGRWRRVHVSDDDLLSISGVNSVFFEEALHYLISGKWIVI
FDLVTETFKKVPFSIKPDQVSEYNDLLLGVIGEYDRLCAMFIHYLSDEWVIELWTLEEYN
NWNSWIKLYQIELQEDIISNCNQFLGFTYSGYLCMQHENGLVLLDRDDDPPSHVVARNQS
FAKAYKVMDYVESLVSPISIP
>Sgl06532 E3_activity/RING/RING 36.4 4.8
MDLNTLIIPFFLLIISNFPCNKATSTNCSISKCGDSSAGNTPAIRFPFRIKSPGQEPSSC
GRSGFDVWCDERSKHTLIELPRSGNFKVKSIDYAAQEMWVNDPNKCLPKRLLTFNILDSS
PFGEVYHQDFSFFNCSNTLNNTNFTHLKGLLIVGPIKCLSGSHHFVYAMRTNGTTFTNHT
SNLLSPLNCSLVAPSIKVPVQWPPSLHNDTVLSLLADLHGDLRLSWYIPECRPCELNGQM
CALETASNDSDVIICSDIPNEGIAGKLPLTTFIAVILVICAPSIICIVGSIVIWIRHCYK
HRRSNRNTQTGPVDSNGPVNEELGQLAEVNIEFARHIVRMGLNEEANLDRRPTVVISEIE
EVGLGQGPNRENDNMCAICMGEYRRKDRIGTLPSCEHYFHANCINKWLLSRGRFGKTCPI
CRAPVDSS
>Sgl06533 E3_activity/RING/RING 41.4 4.8
MAGILCLLNCLNSACREADSEILINLRPTLAYSSKSMLKGDDDSKRCSICLDDYEDGEMV
EFLDCFHLFHADCIDQWLPLSQTCPVCRLQC
>Sgl06534 E3_activity/RING/RING 38.7 6.4
MILLDILSLMPMACILCLLSCLNTACHHEADSEILITLRPALSYCSKTMPKGDDDQQCSI
CLDDYEDGDMVEFLDCFHLFHAHCIDQWLPLSQTCPICRLQC
>Sgl06536 E3_activity/RING/RING 32.8 4.6
MDSAGNNPPTPSDDGSHTAVKWLGIVGAIAIGLILIRLCWIWCKWWHLQSRRRNNNNNNV
VIDLTYDNSPSPTNEPREVSGLNQLIIDSYPTVLIGKSGSAIKPHEATCSICLGDYVPGD
TIKIVPECIHRFHAECLDLWLINNITCPVCRIPPQNISSVV
>Sgl06537 E3_activity/RING/RING 33.2 8.6
MISKATVEGLKERIGYSSAFGVSSVGKSGGLCLFWQEDIVDFSLVSFSQNHICGDMRMGE
EAWRFVGMYGWPDSSAKHKTWDLICDLTRNSPLPILLGGDFNEILSWDEKEGGVIGARRE
IDQFREALNVCELRDLGFEGQWWTWERGKTVETCVRERLDRFLASSAWCRLFPNARVEHL
LRYRSDHAPIVIRLKYKKKRGRGRSKSFKFETAWLLDDSCKAEVKASWDRASGCALEDKL
LRVGGSLSSWSKEKFKDIDGKIEKAERDLRDCQSQGINQERCELQAKIEEQLNDLYEKQE
ALWHLRSRVQEIREGDRNTSYFHHKASQRRKRNMISGLYDKEGILQEDEECMEALIADYY
TTIFSTSSPDASVTEEVLSLIPQCVTAVQNSNLLQPVSSSSTECCETMYCNNITSHGNKI
EFPYRLRGEQPESCGCHGFDLYCDDELGLLLELPHAGNFTVEYIYYSTRKIRISDPNECL
PQKLLTVDLSTTPFRGEEESVDYHVYNCSGVGDELDSYGEKIDCLSGSNYTIISDSSNKR
VDDLNILKCLFIKHVSIPFYLPSTYMANAKHPFRVTESCGCQGFDLYCDDEFGLLMEFPN
AGNFTVDYIFQYSEREIQLSDPNNCLPQRLLAGLNLSMTPFRLTRSVDFQLYNCSGVDYP
MDSDYVEKIDCLSDADFDYSFLSIYSTIDLTWDEHDECISCVLAKEKRSGGRDSYSKVAI
VVFIVGITVPVSFVILFVICLCCRRGETPRNQSAINTNADASTNTSATASSGLDQVTINS
FPTVILGEHGGLTNKSEHDTCPICLSEYSPKDVLKMLPHCLHRFHADCIDMWLKSQPTCP
VCRTSPTLRFTDCV
>Sgl06541 E3_activity/RING/RING 35.5 5.9
MVMFDGRILPFAVVFSIMLLIYILCKMGWRKRGEAQLPVYVTEAQDQTQGQAQAQPQSQS
QAQEEPKKGLDQETIDSYPTVVIGKKMLMKLDDNMCSICLSEYRQNDVLKVLPECLHRFH
SDCLVEWLKLNATCPVCRTHPPRLNPTAS
>Sgl06542 E3_activity/RING/RING 35.7 10.7
MVDYIFILITIFGITLFLSSLCWSCRTSVILVRFSIRLSMAQAQPQAHDQQVENKGLDQE
TINSYPTVVIEGNDGLLHHQDDDTCPICLSEYDHNDVLKVLPDCMHQFHCDCLDKWLRLN
ATCPVCRTRPPHLGTSIS
>Sgl06543 E3_activity/RING/RING 33.3 17.1
MNRHNHQPSYVFDIAPSPRRGGGTTSSQSHSPPPAAVGTIGLDEVTIDSFPSMIIGESGR
MIKKDDNSCPICLSDYTPKEKLKMLPLCLHRNNVFTTSPKMHFLKNYTIFFLLCVLLPKS
TKCKENGSKLSDFCITQVCSYREPVTRYVQFPFLIRNESLPQSCGYPGFDLLCDGDYRLL
INLPNSGVFSVEEIDYVNQELWLNDPDDCLPKKLISLNGSNYVSKSPFNPVLEQDYWFYN
CTNDFFNSSDDEISVIQCLSGENYSVFATTMEDIVKGKNSSLCGKIGPIKVPVRKRSFEV
YSSLELENDILLTWTILRECGECYQKNGKCRFKSGSGLEVGCFNLPRRGLSRSAMFAIAV
AFVTPLVLVTCCFAYFIVKAIWYRRRTNRARLPSFAELALAVTPQPERVIQGLDQTTIES
YPKVVLGESRRLPKPDDKSCAICLGEYLAKETIKTIPDCGHCFHDHCIDEWLLLNATCPL
CRNSPSKTPQSNA
>Sgl06544 E3_activity/RING/RING 32.3 8.8
MSDHCSIQVCKFDDPISRYVQFPFLIKNDSMPSFCGYPGFDLFCNEDDKLTIKLPNLGAF
LVEEIDYVNQELRLINDLDHCLPKKLLSQNGSSFVGKSQFLPIIEQDYWFFNCSNDFFNY
SNVEPIECISGTSYGVFATNVEKIRYSNSSMCQKIGPIKVPKGVNERNPSSILSGDFRLN
WYHPRECVTCHEKNGRCRFKGNSNLDVECFFPGRGLTRNAMVAIGLAFTAPLALITFIIV
YFVIKSVTNGQGRAGSRGEGVTLTPQPQNAGHGLGLDHDVIESYPKVVLGESRRLPKADD
VHCPICLGEYVAKESLRTIPDCGHCFHAECVDEWLHLNASCPICRKYPSKPPQIDDT
>Sgl06580 UBD/UBC-like/UBD_UBC 248.9 0.0
MASKRILKELKDLQKDPPTSCSAGPVGEDMFHWQATIMGPPDSPYAGGVFLVTIHFPPDY
PFKPPKVAFRTKVFHPNINSNGSICLDILKEQWSPALTISKVLLSICSLLTDPNPDDPLV
PEIAHMYKTDRAKYESTARSWTQNANCRALTSVRCTPVDKPLLLLHTLEHHSLLLNHLLV
EMPEIQLGAHTLRSHGVQVAKIHMHDWLILFLLVVIDIILNVIEPFHRFVGKGMMEDFMY
PLKGNTVPFWAVPMIAILLPFCVILIYYFIRKDVYDFHQATLGLLFSVLITSVITDAIKD
GVGRPRPDFYWRCFPDGKGVYNNVTGDVMCTGFKNVIKEGHKSFPSGHTSWSFAGLTFLA
WYLSGKIRCFDRRGHIAKLCLIFLPILLAAMVGVSRVDDYWHHWQDVFAGGLIGLVISSF
CYLQFFPPPYDPDGWGPHSYFHMLEESRNGVQHQRTSAGALSVRATEIEGIQIEPRHGSD
GSDFQHYQRNDREGGMS
>Sgl06589 UBD/UBC-like/UBD_UBC 252.7 0.0
MASKRILKELKDLQKDPPTSCSAGPVGEDMFHWQATIMGPPDSPYAGGVFLVTIHFPPDY
PFKPPKVAFRTKVFHPNINSNGSICLDILKEQWSPALTISKVLLSICSLLTDPNPDDPLV
PEIAHMYKTDRAKYESTARSWTQKYAMG
>Sgl06644 E3_adaptor/Cullin_RING/DCX/DWD 55.7 5.7
MLKERMENMKYAEELVREFLVFRGFTSTLQAFETELSTDVGKDFQVDKILDLIFSKYVPK
FEAEKLVGLFSFFKHCFSSSETVLYATLSKLEASVLRYYIVHAKRSGRNDKVREFFDMLG
DSLQQKGDDWTPWFAIPYLKSPGTDPQFCIYFSKEWLDALHLSLRNFLSQMFSSTRIPAL
LKISTEKNTVKHLRRDIKQLNLKLSQLQAVLEEREAQLQQLRRDDVILRREDDSARTSAF
SEDATLSNDSRENLVSTSRSGLETGFQSFGCSELPNRTARSANHTLRNSVNSPINNDQNG
AYNFSSEKVAVALGEEEFSEVKVQFQETFLGHTSPISRSRFSAAGDNIASASLDGTVRIW
TYDSSSPGSRNATIYCGAEILSLDWDCKSDRLLLIGTAEGGIKAWNVDAKRVVCDLSTGQ
TFRRVLDIKCSPVESIFVSAAASEGDVTAYGSTMGHASLTVWNMKTWKAMSVLPLGEEPP
AITSLCFNHNGKILAAAAVDGMIHMFDMSAGLQITGWPAHDTPISSILFGHDETSIFTLG
SDGKVFEWSLQKQGQVVWSANCSRFCSPDTLKHCRHEMALDFTGKRLLVTSDLVRSPIYQ
VGSLANGSKTLPHSAAITTVDWHPTLPIYLTGSADNSVRVTSIS
>Sgl06650 E3_adaptor/Cullin_RING/SCF/F-box 21.2 0.0
MNGALERYQNLKLRQSLSLSYRYSMACKELGVILRLSYSKSPKPLQSLLFDDTLFAFRLL
PKMQTQTDVSAANHLIQCAEAVLPKQKRSVATTEFKQSKVAYKRRAKTPKEDKDLIQLPQ
DVLVHLFSFLDLQSLACTSLVCWSWNAAANDNYLWQFHYNSHFGDLSTLKREDLQTEDRQ
HGASDGACKVAAYDWKDSYRRAYIGLPNRGYKYHRGYCGFCNSIVWLNSLKCPNKHAGQI
FGNKLLKPVSPAQIAIYI
>Sgl06705 E3_activity/RING/RING 23.4 12.8
MGILFSGRRNQNQNHHHHHHHHPPYYHHTPPPQPPPQPYYYHPTSTTTPPPAAIVEQTPL
PLPLPPPQPQPQPQTNSYVHLSPAYPSTQYQYQQQTPSVQSNCYYPGWSNNSNSYSNHGN
YYQNPIMGAPNFPYFPTNYGNGWHQMRPPLSQPQLQPPPYVGHQSAKVVKNDVNVHKDSI
KLVEDELYPEHFLVSFVFDAHFDGSITIYYFAKEEKETGTFTPAYSEAIKSVKVPFQKGA
GQRFQQASGTGVDFGFFDLESLGKPSEDDIFPLVIVAEVCSSEEGESSASSSPRAQVTQA
IIENTNEGSFHVKAIRQILWIDGVRYELRDLYGIGNSSSETFNDDEPGKECVICMTEPKN
TAVMPCRHLCMCSDCAQELRLQTNKCPICRQPITELIEIKINNTSQ
>Sgl06728 E3_adaptor/Cullin_RING/BCR/BTB 64.9 0.0
METVNGTHEFKIKGYSLSKGMGIGKYIASDTFMVGGYLWAIYFYPDGKSPEDNSNYVSLF
IALASDGTDVRALFELKLEDQSGRGRHKVHSHFGRTLESGPYTLKYRGSMWGYKRFYKRT
SLEQSDYLKDDCLLIRCIVGVVKTNTEGPKLYKISVPPSDMGQQFGQLLETKKGTDVNFE
VDGEFFDAHKLVLAARSPVFRAQLFGPMKEKSTQCIKVEDMEAPVFKALLHFIYWDDLPD
MQELAGLNSKGASTLMAQHLLAAADRYGLERLKLLCETTLCEDVAINNVATTLALAEQHH
CSHLKSVCLKFVASRENLRAVMQTEGFEYLKLSCPSVISELLAFVAKVSEHSTAVVAYGN
DPMLDCGDVNGRRVKPRIF
>Sgl06734 E3_adaptor/Cullin_RING/BCR/BTB 70.2 0.0
MGISRVSNDPSTSSAETCSSSIAIVETVNGSHEFKIKGYSLSKGMGIGKYIASDTFKVGE
HSWAIYFYPDGKSPEDNATYVSLFIALASEGTDVRALFELKLEDQSGKGVHKVHSHFGRP
LEDGPYTLKYQGSMWGYKRFYKRTSLESSDYLKDNCLVITGTVGVVKTRTEGPKQYIIPL
SPSDIGKNFGELFERRNITDVSFEVDGEIFSAHKLILAARSPVFRAQLFGPMKEKNMQCI
KVEDIEAPVFKALLHFIYWDELPDMEEATGLNYKGVSTLMAQHMLAAADRYGLERLKLLC
EVKLSKDVAINNVATTLALAQQHQCLQLKAQCLNFVALHENLRAVMQTEGFEYLKESCPT
VISELLGYVAKFSEHSKSFLTFGNETLDGGDVNGRRVKQRLF
>Sgl06737 ULD/UDP/UBQ/UBQ_PIM 88.2 0.4
MKLTIKTLKGSHFEIRVQPNDTVMAVKKNIEDVQGKDNYPCGQQLLIYNGKVLKDETTLS
ENSVSEDGFLVVMLSKSKSLGGGGTLSTQHPTPAPSTTTAEPTPIPAPSTTTTEPTPSPA
PSTTTAASPPEAQMASKGESASNALSSSAPADTYGQAASTLVAGNTLEQTIQQIMDIGGG
SWDRDTVIRALRAAYNNPERAIDYLYSGIPQTAEIVEPVPQFPANQANTVTESGTTPVAV
SGAPNSAPLNMFPQESMADAAAGGIGSLDFLRNNQQFQALRSMVQTNPQILQPMLQELGK
QNPELLRLIQDHHAEFLQLLNEPLDGSEGDIFDQPEQDMPHAISVTQEEQEAIERLEAMG
FERALVIEAFLACDRSEELAVNYLLEHADDHDD
>Sgl06742 E3_adaptor/Cullin_RING/DCX/DWD 71.6 7.3
MVLLAASGGDTVKLFDVSVGSGDPCSLNYTPSPGFQVNSVKWNHTNLVVASAGDDKKITL
WRKNGQSLGTIPLLGSESGDNIEEAISSLNFSNKTSRYLCSGGSGQVVRIWDLQRKRCIK
WLKGHTGSISSAMYNCKDEHLASISINGDLIVHNLASGAKAAELKDPHRQVLRALDYSRV
SRHLLATAGDDGSVHLWDTTGRSPKVSWLKQHSAPTAGLSFSPSNDKVIATVAFREDGLI
LAAGTSNGRVVFYDVRGKPQPFTVLRAYGTSEAVTSLCWQRSNPMVVNEKNCTSEVALVG
GAVEDSILMPDPLPSATSSSGPQSTTFSGPRRSSSAVESNFAATMTNSNISSEETPHRNS
LWAGGALPRLHAARNYNFKDDMDVFSPLVDVQPITPAHDRLWNEPAGSRKDQPGDKQTSP
LFPNRKFVTSEAITDVHPIFDWKPGPASKQDDMQSMLSGSTPSASSSRSDDSSSITPPEA
WGGERLSDKLAYHRQLGSLPSRFSIPTSTSTTSTSLFTGLQDPSASQSTMNFPTSTSLIS
GNLRAKDIASGQDNSLGPLGHVPFSALPNLGSKSAIGQANIEATTGPLSTMGLSRRYSTY
EERIRTLSLNEGVSASVGSPKTKKTGAETREDLHSSLLARSDITHASEPGLLSSINGAPN
LQQGTPQADLQQGSSNFTLQLFQHTLQETLSSFQKSIHEDVRNLHIEILRQFHMQETEVS
GFMTTVQDKLTSLTEEIQDLKKENERLRQLL
>Sgl06761 E3_activity/HECT 366.6 0.1
MFFSGDPSARKRVDLGGRSSKESDRQKVVEQTRLERNRRMFQRKQNSAAIKIQKCYRGWK
AVEAERHKVREQFFATYGKRCQNVSRDCFGPDSRFLGELLFFLNPRNADDLTALAETGRL
LQHFAQDTGGLVTLFAGMDYSTNHCLVSYRVKQLTYACIRAVHAKRSQLKKQSFLSESNS
HILSVFLEATVLLIDPKLPWACGIISYLLQRNAFTLLREITFAVKESLNPQNMIKVSSLE
QVLILIMSHVGEKPCVCQNADQRWIFSSQILTIPFLWQMFPCLKEVFARQQLFKHYVHQM
SLSVRNHINSLAKDVSAEYPSYACLLGNILEAATLAISETDSSFEMAVDFVSVATFLLDM
LPPLKSVSKETNESSSMEDDEMIDAEEYNGNALCENLESQISNAIDPRFLLQLIKVLLGG
VPPFTSGNCPGDKEVVAIGAACAFLHVTFNTLPLERIMTILAYRTSLVPVLWSFMKRCHE
TQKWSLVAEQSSYLPEGVPGWLLPLAVFCPVYKHMLMIVDNEEFYEKEKPLALKDIRYLI
VILRQALWELLWLNPVAPSNFVKSKSKSLAYKKQPLEFLQYRVSIVVAELLTQLQDWNNR
RQFAPSSDFHADGVNEFFISQAMQENTRAREIVKQAPFLVPFTSRVKIFASLLAEARKVD
NARAVFSRNRLKIRRDQILEDAFSQLSTLSEDDLRERIRVTFINELGVEEAGVDGGGIFK
DFMENVTRAAFDIQYGLFKETADHLLYPNPGSGLVHEQHLQFFRFLGTILAKAMFEGILV
DIPFATFFLSKLKQKHNYLNDLPSLDPELYRHLIFLKHYQGDVSDLELYFVIVNNEYGEQ
TEEELLPGGKNTRVTNDNVIPFIHLIANHRLNYQIRQQSSHFLRGFQQLIQKEWIDMFNE
HELQILISGSLDGLDIDDLRSHTQYSGGYHAEHYVIEMFWEVLKGFTQDNQRKFLKFVTG
CSRGPLLGFKSLEPQFCIQRAAGDASEESLDRLPTSATCMNLLKLPPYRSKEQLERKLLY
AISSEAGFDLS
>Sgl06781 E3_adaptor/Cullin_RING/DCX/DWD 43.2 15.0
MEGEFCIDCLKHRIQSDFSDKLFFSYAISDSVLPFSSKAVVQMPNSSGEVSEFVLVYLPQ
QQDECITKYVDDHILNDDECIENHGEIHQSTSEEVCDNSFSSPSPSQIQVSPLLSSKMKT
EVCDLYCDNSSFYYSGRLSCLRAITALAPCAFVGNCTFDAFGKIASSFSSGWLEDDTLCS
LSVMIEGKAICHSSRNFLSLLGIPSFCGNQVPGCLRHPNLVPVLGMLKVPGYNSVVFPKA
PYTLENVLHYSPAALNSEWHTRFLIYQLLSALSYIHSLGMAHGNIRPSMVMFPSSSWAWL
SICDRPYMQYISADKDEDPLVSPVTRKSCSSHDCLSKSLYADLNLSSSVDWPTDFYRWWR
GELSNFEYLLVLNKLAGRRWGDHTFHTVMPWVIDFSVKPDENNDLGWRELSKSKWRLAKG
DEQLDFTYSTSEIPHHVSDECLSELAVCSYKARRLPLSVLRMAVRSVYEPNEYPSTMQRL
YQWTPDECIPEFYCDYQVFLSLHSGMNDLAVPSWARSPQEFIELHRNALESERVSREIHN
WIDIIFGYKMSGQPAVAAKNVMLPSSQPTKPRPIGRRQLFTQPHPVRWGNTKRIRDLATV
GETNSLLHENIVDVETPSFQGTHYLKRIEDIATFCQHSRHLSPMYSENIAKSSSDDMESS
SQERECHATETTENRISFGMLPVIDSNSLLEFLEEDEGSEGYQELLLWAQQSSCQRKLST
CVAKDIFSLGCIIAELYLRKPLFDSVSLSTYMDSGALPGMLGELPPHVKIVVEACIQKDW
RRRPSAKSLLESPYFPTTVKSTYLFVAPLQLLAKDASRLRYAANFANKGAFRVMGTFAAE
ICTTFCLPLLENSLSDVEADWAYILFKEFLKCLKPEAVKRLVLPSIQKILQAIGYSHLKV
SLLQDSFVREVWNHVGKQIYLEILHPLVISNLLNSPHKSSASAASVLLIGSIEELGIPIA
IQQTILPLIYCFGKGLCADGTDALVRIGAVMGENFIVSQVLPLLKNVVHSCIDTSSTNKP
EPLQSWNSLALVDCLFVLDGLIAFLQTEVVVKELLEGQRCLFVMILMQSNLELPVLQAAA
ATLMTVCKQIGPDLTTVHIVPQLKELFNELAFSQELSGVPTSLGKSYKVSKLRPDKEAQI
ESRMDLVSLLYPSLANILGIEQLRQCFATWLLLEKYLFRCHNWKWECTGDSSRSSSGNFN
GKQAINKESVKSKYNPTNMLMNGVGWAVPQSQGSKGGNDMVIHRRFYEFRQNSVEGNSEA
SRVGKCDPWFWFPTPASNWEGPDFLARSGTSKDELPWKIKASVVHSVRAHHGALRSLAVD
QDECTVFTAGVGPGFKGMVQRWDLSTVDCVSGYYGHDEVVNDICILSSSGRVASCDGTIH
VWNSQTGKAISIIGESSANLVQPSISSSSSSSTRINNDQANLLNSYPHSGGIFTSIDGSL
YTCMHFLESVEKLVVGTGNGSLRFIDPAFGEKLHMWSSESKEYGFPSLVSAVCSCGSDKM
ESSSSHSWIAVGQGSGNCKLLDTRSGNVIASWRAHDGYVTKLAAPDDHILVSSSLDKTLR
IWDLRKSFPPQPTVYKGHTDSILDFSIWAQDVISISKNKIGLSSLAGALDEYGQHNIVRQ
ALHTEDRGARNISVLSSISILPFSRLFLVGTEDGQLKICC
>Sgl06795 ULD/UDP/UBQ/UBQ_Other 45.1 0.1
MQIFVKTLIGATITLDLEPKDTIKDLKSKIEEHEGIPKDEQSLIFGDKEVVEYGDDYENE
EGHTLTHYNINKGSTVPFTLHQDLPTRKTLRSKCVASAMLDCHQMPNATNCRKKKCGHSN
QLRPKKDRGWF
>Sgl06832 E3_adaptor/Cullin_RING/SCF/F-box 20.8 0.0
MNSLNSRNGVFPDEIILQILARLPIKSLFRLRSVCKYWYELLSDKYFVSLYNEMSVKSSM
ILVEITEVSESKSRLICVDYLRGVSEFPLDFLKDRVRVRASCNGLLCCSSIPDKGVFYVC
NPMTREFKTLPKSRERPVTRFYPDGEATLVGIACDVADSARFSVVLAGYHRPFGYSPTKT
FICMVYNSEMNKWRKFVSLQEEHFTQMNRNQVVFVNGMLHWLTVSYSCILVLDLEIDVWR
KIYLPVEMSYGTGNRMYLLESDGCLSVVQISDAWMDIWVMENYEKQEWRMVDRVSLRCIR
GLAPGIFPISQAGECVFLATLKQVLVYNRSTSVWKEMYSVKSNSTLPLWFSAYAFRSTLF
HFTK
>Sgl06846 E3_adaptor/Cullin_RING/SCF/F-box 39.1 0.1
MEVFPPELINEILLRLPAESLLRFKTVCKSWNSLIKTPSFIKSHLNQTLISNSHRLLVKS
SIMDYSKKRKFSFYSAEIDSDSPTPDRRLSYSMRNHPLDDFNNATVFGSCNGVVSIRDFS
RPNNVLLYNPFTDSRRILPAKGLPNHGRLRRILIDIDSLVTGWFDLETKKFEERKCHGQP
NEYFYDRRYFVGSLVSALPSEIIEEILSRLPAESLLCLKTVCKSWNSIIKTPSFIKSHLN
QTLISNSHRRLLKSPKIMDYSKKRKLILYSAEIDSDSPTADRRLSFSMSNHSLDDYVEVF
GSCNGVVSICDYSRTNVLLYNPLTKSRRILPAERLPPGYKSERSRLLYGFGYDSKTDDYK
VLRIAQGYRSLLYPFYETDHICSVYSLNNNCWKSIHGIVSKQYYYFPYPNSHGVLANETL
HYLVTSNISYESDDLTRPGRMIVCFDFRTESFSLMDCPNHQDENNNDNDNNLMNMMIRSC
KCSYLAELDGCLCFMLMYFSMNEYTRELPEFVRADISVMKEYGNKESWSKVYSISDDQLR
IVSYRSFTRVKLVVYSKDRRRILIDIDGGFVTGWFDLETKKFEELERHGLPDEYFDTRYF
MGSLVSVGHTN
>Sgl06847 E3_adaptor/Cullin_RING/SCF/F-box 18.4 0.1
MEEFPPEIIEKILSQLPVESLLCLKTVCKSWNSIINTHEFIKTHLNQTLISNSHRRLLRS
SMDSKKRKLSFYSADLDSDSRTDRRRLSYSMLNHSLEVDYATVFGSCNGVVSILDFSKPN
NVLLYNPFTKSRRILPAPSYNNSNNKWELVDLLYGFGYDSKTEDYKVLRIVEKYRYLVDQ
PKSFYEADHVCSVYSLNKNCWKSVSGTVLNRYAFSYPSSHGVLVNETLHYLVMSTANEYP
RRMIVCFDLRTDSSSLMDCPNHDDKNSNNLIGRIDSYLAELDGCLCVMFMYFSMNNHNVR
ADLLVMKEYGNKESWSKVFSIRNDQLTSVCTSFHRIKPITYSKDRRRILIDIDGGFVTGW
FDLESKKFKKHKHRGTSFRHFDTSSFTGSLVSFTRTK
>Sgl06857 E3_adaptor/Cullin_RING/SCF/F-box 11.9 0.0
MKQKRIKSPPKSLPIDVIHDEILTRLPAKSLLRCRCVSKLWCSLISTPSFMSTHFKKCQN
NQEKTRLLVLEPPDMCDSKQICAIRSGEKFRKMSKIGLDVTWFEQYQAVSYVNGLLCMKK
YVKETQLSEVFLWNPSIRKAIELPFPRFSKDTKARYDMDCALGYDHVNNDYKVVASVYVG
NELRIPKHIEVFTLSTFSWESASIGNGPCMWIKDGPKVFLNGIIYWGAIHVLKPTPKGRF
SQFVSFDVTNDAFEYIDLPDNGHVHEWEYERFPIILDQSVGLMKVFESYSQIWVMEDTTK
GNKAQSWIKRFTINLQLLEKFIYFKMDGELLFEGEKGGVNSYNIKTQETKVLAKSYKLSP
VFTSVYMESLALIEEVHERTSYTFPPEKTIKSDCDLGSSFLYLFPNAISSFY
>Sgl06867 E3_activity/RBR 150.4 29.7
MESDEDPLDAYDGDSAEDYYYSGGDSDMGDSIDGVGDYDDDDDDDDGAFAYASDDESFLQ
HEKNYTVLKVGDIQQREEESISHVSSVLSISRESASILLCHYKWNVSQLHDAWFADEERV
RRTVGLLSTPVVFSNAKELTCGICFDSYPRDQIHSAVCGHPYCTTCWKGYITTSINDGPG
CLLLRCPDPTCCAVVGQDMILHLVSDEDKEKFYRYLVRSYVEDKKKTKWCPAPDCGNAVE
FEVGSCVYDVKCLCSHAFCWNCSEEAHRPVDCPTVNKWILKNSAESENMNWILANSKPCP
KCKRPIEKNHGCMHMTCTPPCKFEFCWLCLGAWTDHGERTGGFYACNRYEAGKQEGLYDE
DEKRREMAKNSLERYTHYYERWASNQTSRLKAVTDLHQMQTIHLEKLSDKLKEPESQLKF
IIEAWQQIIECRRVLKWTYAYGYYLPDHETAKRQLFEYLQGDAEANLERLHQCAEKELLV
FLGNSDSDTDIQSDFKIFRPKLAGLTRVTRSYFENLVRALENGLSDVDSQAASSMSVTST
NVGAKGKGGKVKSSTSRTGRSVARNNIDDVNHWNCERCTFANPDSSASCQMCHNRR
>Sgl06913 E3_adaptor/Cullin_RING/SCF/F-box 18.3 0.1
MMKNEELNLIRSLSEEIPSSIMVDILLRLPIKACLNCKLVCKDWYQIIISSEFANLHSSQ
CSFSTILLYGKFNSKKKDFLMFDLDKSSKVDEMGNLSVDANALIRFKSKLNTSHDKLYVV
NECNGVVCLKSWEQWSPYIICNLLTGQQVIVEQLPNSCCSVEVYGLGCCPVSHQYKVLRI
LKLKGTDRCVTEIQTLGTNEWRTVGDAPQFQLRRSGAFLLFFMARFTGIRIGITVYGHFS
LEMSSFHMFQYLMI
>Sgl06914 E3_adaptor/Cullin_RING/SCF/F-box 20.1 0.1
MKSMKTVKTNRSPVEEIPPEVMLDILSRLVTKTCLNCKLVCKNWYRMIISQEFADLRSST
TRSCSTTILVHSPFQVGKKKRTDFLLIDLDKSCKVDEDGSLIVSNNDAVIRFKSKLNDLS
HSNLSVVNECDGVICLACHRRWKSYVICNLLTGEQVVVKQRWRKSCVGTYIYGIGCCPVS
RQYKVVRVLCMSTTTSENNKSVKYKVVTEIQTVGTGEWRRVIDVPNKGSLMYCDYSPKAF
LHGSLHVYYSPDKPKYIWSFNFETERFSRLPTPVQIRGWRAKQSSFVSVFDSCLCFNTYD
DESNQCVIWLMKKYGDKASWIRQFVIQPLDHWLNLPLLRMSTGEIPVSGWRTLQSYLEAP
SRGKNVKFHGGFPFRSLTPFNPKFSKINTATPVEVKLKRRCTLRTQWTSLTKKCNNRLH
>Sgl06916 E3_adaptor/Cullin_RING/SCF/F-box 19.9 0.0
MKTVKTNRPPVEEIPPEIMLDILSRLVTKTCLNCKLVCKDWYRMIISQEFADLRSSTRSC
STTILVHSQFQVGKKKSTDFFLIDLDKSCKVDEDGSPIDSNNDAMIRFKSKLNLPRRNLS
VVNECDGLICLACRRWKPYVICNLLTGEQVVVKQQWRESCVGTYIYGMGCCPVSRQYKVV
RVLCMRTTTSDKSTKYKFVGEIQTLGTGEWRMVIGDAPRCQFLQPKAFLHGSLHVYSIEE
NCIWSFNFETEQFSKLPTPVEIHGRRAKNSSFVSVFDSCLCFTSYDYENKRVIWLMKKFG
DKASWTRQFLIQPLDHWFNLPLLRMSTGEILVSGWRTLQSYLSSRGKNVNFHGRFPFRSL
THFNPKFSKINAAIPVEVNLKRRCTLRRYVLNELH
>Sgl06991 E3_activity/RING/RING 19.1 8.6
MVNDFMVCVDRIIASACLQSVETNSGFHHQIVDDDDSNKKNQKFKLETLNTTISSSSSSS
CLLQKECRICQEEDDDISLESPCACNGTLKFAHRKCIQKWCNKKGDITCEICNQVFTPNY
TLPPKPASDVMAVDISQAWGHHFTFRDHQLLALAAAERQLLESEYDDYAAANAGNVTYLR
SIAIILMFVLLIHQVLMITRDFGLMQGYLTVFHVEVSLLQLAGFLLPCYALLRSWYILYT
RRRRQG
>Sgl06997 ULD/UDP/UBQ/UBQ_Other 30.3 0.2
MDSEAASSSRNDQESDDDEEYEEAGGGNGLLGFMFGNVDNSGELEVDYLDEDAKEHLDAL
ADKLGPSLTVMDFSGKSRHTSVAVSAAEEDYDEKADDAVDYEDIDEQYEGPEIETATEED
HLLPRREYISADVSVATLEHRPSCFDDENYDEDVDDEKELDDVVHESEIKSAAETDFSLK
PQDADQIEPVDNSFGTQVIASPVKLGDDDMNFSQEIHSESLLAPVPVQSEVAAVFPELQK
QEEPIVSHNTADAKSLRPLPILCVEDGEAILRFSEIFGVNAPLKKAGRRGHRYSVPKDKY
ISLDASHMVEEDEESILRGSCNVFSNRNLLLHETQDRDEMSMDDDSKLDLAEGMHSVHDK
KKDFCLSAEPMRKDSAFDLSDEWKSCMSMEFYSLDQQDWEEKIMWGNSPSVSENSVESCE
LSGPDSEHVAHEEKELISRPQTLLSDSKTEQCEKDKCCHNGFVNFSVESFGTRDSATAAF
SESLFHPQLLRLESRLENDSSSLSDRRKENESEEHEQLDFMKRFKQLTLQNKELVEGSWV
ENIIWEAEKPIVKPKLIYDLQDEQMVFELLDNKDYEHLQVHAGAMITTRSGKAGAEAFEG
PSHGTFSGGRFNISSDKYYSNRKTSPQLKSLSKKRTAHSVKVLHSIPALKLQTIKLRLSN
KDITNFHRPKATWYPHDSRLAVKELEKLSMQGPMKVILKSLGGKGCKINVDGEETINSLK
VKASKKLDFRLTEAVKVFHMGNELDDQRTLVDQNVRPNSLLHLVRTKIHMLPIAQKLPSE
SKSLRPPGAFKKKSDLSVKDGHVFLMEYCEERPLLIGNVGMGARLCTYYQKTSSDDQNGE
MLRNAKNGLGTVLSLDPADKSPFLGDIKPGCNQSCLETNMYRAPVFPHKVASTDYLLVRS
AKGKLSIRRIDKIHAVGQQEPHVEVMSPGAKGLQTYMINRLLVYMYREFRAAEKRGMLPW
IRVDELSAHFPNIAEHFLRKKVKHCADVQRGPNGLSYYAMRRNFHIPPEEELRRMVTPET
VCTYESMLAGIYRLKRLGITRLAHLTGPTQLAALSSAMNQLPDEAIALAAASHIERELQI
TPWNLTSNFVACTSQDRENIERLEISGVGDPSGRGLGFSYVRVASKPPVSNALVKKKPAV
PRGTTVTGTDADLRRLSMEAAREVLLKFNVPDEQIAKLIRWHRIAMIRKLSSEQAASGVK
VDPTTISKYARGQRMSFLQLQQQAREKCQEIWDRQILSLSAVDADENESDTEANSDLDSF
AGDLENLLDAEEGEEADEGNLEMKNYKSDGVKGLKMRRHASQARLEEEIEDETAEAAELC
RILMDDDEAEWKKKKKPKPSGEARGPSRGPQLSFGFEKTEQVKKPNTMVKYADGHVDVPL
IGKQNADIDEVEKLHTKKLMSTKGKTAKKIDALPVDLLNKKVKIMTEGIYKGYKEKKSAR
ETFVCGACGQLGHMRTNKNCPKYREDSEAQENNPDLEKELVKPVSQDLPSQSQQKISSKK
LLTKNVNKVSQIEALEGEKSSSKTKVLKVRYAAPDKVPSGQLLSSEQPSTSEAEAGNKSA
PKVIKIVSNKMKPDDVQAESAKLNVIIRPPSEANKEHLHKKITIRQPKEVINLDQSSQEG
PDTEYRKTRKMIELTGFGVNREQEGKPLYEETFKKKKKEAKRMREEEERRRNAERIKEQE
ARRLYEEEMREQDRVAELRRYEEDIRREREEEEWRKANKKKKKTKRTIELKDDYVDDLSA
KRNNRLVLERERSAKRKTIVDLGRHGAESVPPTKRRRGGEVGLANILENIVEILKQRTEV
SLLFLKPVSKKEAPDYLDYVTRPMDLSTIRDKVRRLEYKDRLDFRHDVHQISYNAHLYND
GRNPGIPPLADQLLEICDYLLNINAKRLEEAESGIND
>Sgl07007 ULD/UDP/UBQ/UBQ_PIM 53.2 0.2
MQVIIVTNNFTNFSLEITPREPVLVIKQKIANILGIPVFFQTLSVLGIELINGLDMDDYP
IINEGTRIDLIVSSTDEEMIMPPMDDYYTEHTSSHTKIPVTIKFSTREINIEVDMITETV
RSLKEKIHIIDGTPIKRMLLYTSGVEMEDDYRLLSEYAIHEYSEIAVFLRSMNRLKAEPP
CRKLKMVVQTSKSLLNAASIPLEMKDSCTLNEVRQFMLSRRILPMDDYIFIHKQRIMRDN
CTLRWHGVENEDYLYVFKGTISKNGC
>Sgl07012 ULD/UDP/UBQ/UBQ_Other 57.1 0.0
MQVIIVTNNFTNFSLEITPREPVLVIKQKIANILGILVFFQTLSVLGIELINGLDMDDYP
IINEGTRIDLIVSSTDEEMIMPPMDDYYTEHTSSHTKIPVTIKFSTRKINIEVDMITETV
RSLKEKIHIIDGTPIKRMLLYTSGVEMEDDYRLLSEYAIHEYSEIAVFLRSMNRLKAEPP
CRKLKMVVQTSKSLLNAASIPLEMKDSCTLNEVRQFMLSRRILPMDDYIFIHKQRIMRDN
CTLRWHGVENGDYLYVFKGTISKNGC
>Sgl07023 ULD/UDP/UBQ/UBQ_PIM 54 0.1
MQVIIVTNNFTNFSLEITPREPVLVIKQKIANILGIPVFFQTLSVLGIELINGLDMDDYP
IINEGTRIDLIVSSTDEEMIMPPMDDYYTEHTSSHTKIPVTIKFSTREINIEVDMITETV
RSLKEKIHIIDGTPIKRMLLYTSGVEMEDDYRLLSEYAIHEYSEIAVFLRSMNRLKAEPP
CRKLKMVVQTSKSLLNAASIPLEMKDSCTLNEVRQFMLSRRILPMDDYIFIHKQRIMRDN
CTLRWHGVENGDYLYVFKGTISKNGC
>Sgl07054 E3_adaptor/Cullin_RING/BCR/BTB 23.7 0.0
MASALCDRSWTPLPNSHMSSSFGLSNTEESPVEILPVSEIPISSFSTQSIIPAPPPLPKS
GFLKRRYKEKSSECFCISKEARDLWDKLFEKGYEADVYLITENKENVPAHSCVLSVASPV
LGKYLQDSKIMNGVRYVKIPGVPHGAVCTFIRFLYSFCYEEDDMKKFALHLLVLSHSFVV
PLLKRVFVQYLEKSWLNTENVIDVLQLARKCDAPRLSLMCIRMVVKNFKLIASTEGWKVM
RRVNPALEQELLESVVEADSRTQEKQQKIEEKKVYLQLHKAIEALSHICKDGCSTIGPRD
KMLKGSEVSCSFPACKGVEMLFRHFFSCKTRVPGGCVQCKRMWQLLELHSRMCDVPGSCN
VPLCRHFKEKVRQQSKKDEAKWKLLVRKVMAAKNLSNSFATTHSGFS
>Sgl07063 ULD/UDP/UBQ/UBQ_PIM 177.8 1.9
MQIFVKTLTGKTITLDVESSDTIDNVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLADYN
IQKESTLHLVLRLRGGTMIKVKTLTGKEIEIDIEPNDTIDRIKERVEEKEGIPPVQQRLI
YAGKQLADDKTAKDYNIEGGSVLHLVLALRGGASSCFSA
>Sgl07073 E3_activity/RING/U-box 70 0.3
MSESKGTVQGQLIVGVALTGSRKSKFLLKWALEKFLPEGNVTFKLLHVYPKITIVPTPMG
TWMPVAQVREEVVTGYRQETEWKKQRKLIPYLKKLKAQKIKADLVLLESDDVPMAISLET
AKQSIRHLVIGVTTTSIFSMKNLSLARGGDLSHNISENVPSFCSVYLVGSDGKLQQLRPA
DAEPNVIAMDDRSNLSSTSTDSSSSPSSLTIGRLLKRTPSSPKYRGSANASDSSHPPSKS
KEPESLPTNGTGPKISARETIELKHFAFKETNFNSGNASVRSHSSSSGDSESWISDRTSP
GGSFVAAHSNIPSPIGTPPSRYFVSTAPTSSFVGTPANYAGTPSTGSFMATPPALSPMGT
PPTSSYMGTPPAHSRAGTPKGGSYVGTPPKVSFLGLSSGSDTGDSQSQITELDKLRIELR
HIEKMYELSQSSSIDERLDKISKERPEEALKLKEEKGKELARVETNKSNESQGEVTYTGE
GAERNKPRNKADTKDAQEAEEIKNKLKNLFASTAVQYQKFTWEEIMAATSSLSDEFKIGM
GAFGTVYKCKLHYTTVAVKVLHSKDSVTNKQFVQELEILSTIRHPHLLLLLGAVPEESCL
VYEYMDHGSLDDRLFKKNGKPPLPWYDRFRICYEVAGALAFLHSTTPRPIIHRDLKPANI
LLDHNLVSKIGDAGLGTMINVGPTNASLKTIYKETSPVGTLCYIDPEYQRTGRVSTKSDI
YALGVVILQLLTAKPAVGIAYVVEDAIDEGTLTEILDPEAGEWPDKETLELALLGLQCAE
LRGRDRPDLRSKMLPILERLNELADCARESISSSYTTTPPHYFCPILKQDVMEDPYVAAD
GYTYERRAIEQWLNENDTSPITNEPLPHKFIMPNTTLLEAIKQWKSRNQTK
>Sgl07075 E3_activity/RING/U-box 133.8 1.2
MNILKLLISSFERIGFCRKHLSLTRGSDISQVISEKAPCFCSVYVIGSDAKLQQLRPADS
EPDVITMDDTSNLSSTSTDSSSSSLLDPLLKSKPPSPRCKGSVTASETFLFTSKPKQPES
LPRNAVGPKIEIARETLELQHYAFKETNFNSASVRSQNSSSGDSESWISDRTSPGVSFVA
AHPNGPSPICTPPQRSFVSTTPTGSYVGTPISYPGTPSTRSFTATPPAGSYASTPAISCA
GTSKGGSYVGTPPLLSHLGTSKGGSYVGTPGVSCTRIPAGGSYVGTPPAVSYAEMPTGGS
YVGTPPLISRAETPTGGSYVGTPTPDSFLGIPSGSETGSSHCQKTELERLRMELNHIEKM
YALSQNHSIDERFLIPLDQLNEISKERLKEAKKLKEEKGKEIARMQKNKSTASQIGVKHI
GGSTEKIKHKNKVDIKASLDADENKNRLKNLLANPAIQFQKFSWNEIMEATSSLSDEFKI
GLGAFGTVYKCKFHYTTVAIKVLHCKNSVTNKQFVQELEILSTIRHPHLLLLLGAVPEES
CLVYEYMDHGSLDDRLFKKNGKPPLPWYDRFRICYEVAGALAFLHNTTPRPIIHRDLKPA
NILLDHNLVSKIGDAGLGTMINIDPTDQSVQTIYKDTSPVGTLCYIDPEYQRTGRVSTKS
DIYALGIVILQLLTAKTAVGIAYMVEDAIDEGTFAEILDTEAGEWPEKETLELALLGLQC
AELRGKDRPDLRDKVLPILERFNEVATSARESASSAHTAAPTHYFCPILKDMMEDPYVAA
DGYTYERRAIEQWLTENDISPTTNQPLSHKFVVPNNSLLEAIKQWNTLLAIHRLSMSNTS
NANQGRLVIGIALTGSRKAKHIIRWALDKFLPEGNVTFKIMNVYPKIVVAPTGPTPMGTW
LPVIRDPVEIENRYRQEIELKRQKKLLPYLHFVYEAQQIQADIVLLESDDIAMAISDEIT
KQSIRHLVIGGPSAGGIFSMKNYAQPTGDELGPIIAKSAPSFCSVYIIVDGKLQQLRPAD
SEQNVITLTIDDTNNSPNSSTDSASGSSSLTIGRLLKSKTSEPQYGGSVNTSDSSHSNSQ
PKQPESHSKNRPKFLTREVVELKHHDFKDSNISNGTGGSGSWASDRTSPTGSYIGNHSDA
RSSMGTTPPSSYVGIPPTQFKNTPPAVSPVGTPPTGSYANTPKAIYHSGTPPGGSYVNTP
PKAPHERTPRSVTFQGVSSGSETGASSNQISEIEKLRIELQHIAKLYEQSQNSSIDKRLN
GISKERLEEAIKDKELARKEKNKYKAGKGEAVDTRGKSEQSKTKNSKDAQEAEESRNRLK
ALFASPAVQYQKFTWDEIMEATSSLSDKYKIGMGAFGTVYKCKLHHTTVAVKVLHSKDSV
TNKQFVQELEILSTIRHPHLLLLLGAVPEESCLVYEYMDHGSLDDMLFQKNGKPPLPWYD
RFRICYEVAGALAFLHSTTPRPIIHRDLKPANILLDHNLVSKIGDAGLGTMINVEPTSAS
LKTIYKETSPVGTLCYIDPEYQRTGRVSTKSDIYALGVVILQLLAGKHAVGIAYLIEDAM
DEGNLTEILDPLAGEWPKKETFELAVFGLQCAELRGRDRPDLRDKILPTLERLKEMADSA
RESASSAQAATPPHFLCPILKEMMEDPYVAADGYTYERRAIEQWLTENDTSPITDVIIPH
KFIMPNTTLLEAIKQWKSRK
>Sgl07108 E3_activity/RING/U-box 135.2 1.4
MPEGVMAVVKPEMKSYVWLQTADGSIQQVEEEVAMFCPVICREILQRSMGSSKINAIALP
ERVNTATLGLILDYCRFHQMPGHSIKERKAFDDKGKDRPDLRDKVLPILERFNEVATSAR
ESASSAHTVAPTHYFCPILKDMMEDPYVAADGYTYERRAIEQWLTENDISPTTNQPLSHK
FVVPNNSLLEAIKQWNTLLALRRLSMSNTSNANQGRLVIGIALTGSRKAKHIIRWALDKF
LPEGNVTFKIMNVYPKIVVAPTGPTPMGTWLPVIRDPVEIENRYRQEIELKRQKKLLPYL
HFVYEAQQIQADIVLLESDDIAMAISNEITKQSIRHLVIGGPSAGGIFSMKNYAQPTGDE
LGPIIAKSAPSFCSVYIIVDGKLQQLRPADSEQNVITLTIDDTNNSPNSSTDSASGSSSL
TIGRLLKSKTSEPQYGGSANTSDLSHSNSQPKQPESHSKNRPKFLTREVVELKHYDFKDS
NISNGTGGSGSWASDRTSPQFRNTPPAVSPVGTPPTGSYVNTPKAIYHSGTPPGGSYVNT
PPKAPHERTPRSVTFQGVSSAKWYKQGAIRGSNRIKSWQERERDKYKAGKGEAVDTRGKS
EQSKTKNSKDAQEAEESRNRLKALFASPAVQYQKFTWDEIMEATSSLSDKFKIGMGAFGT
VYKCKLHHTTVAVKVLHSKDSVTNKQFVQELEILSTIRHPHLLLLLGAVPEESCLVYEYM
DHGSLDDMLFQKNGKPPLPWYDRFRICYEVAGALAFLHSTTPRPIIHRDLKPANILLDHN
LVSKIGDAGLGTMINVEPTSASLKTIYKETSPVGTLCYIDPEYQRTGRVSTKSDIYALGV
VILQLLAGKHAVGIAYLIEDAMDEGNLTEILDPLAGEWPKKETFELAVLGLQCAELRGRD
RPDLRDKILPTLERLKEIADSARESASSAHAATPPHFLCPILKEMMEDPYVAADGYTYER
RAIEQWLTENDTSPITDVIIPHKFIMPNTTLLEAIKQWKSRK
>Sgl07113 E3_activity/RING/U-box 85 0.1
MGSNEGECEELHNYYADGTVFVAVGKHVKESESVLSWAVQKFAGKKRICILHVHQPPQLV
SFFDNKLTISKFKQRAIKALQESDIQKLHKLISQYVLFVSQWGVRADRMWIEKENIEDGI
IKMIAQHGIKWLVMGGAADKHYAKEMTELKSQKAIFVCEQAPVSCHIWFTCRGKLIYTRE
GVNNYPAVDTSLVTGSQNLNMATKESDSRRLRGPSSEFSPKPEPLDSNVVTEEAEQVKVD
EAPAVDGLTLDSDISTEISESDSLESDEVSEEAELVRVIDSSADILSPESNRVIGESGPL
KVDQRVDESRSPPRLTYRERGSILRACSVDFSTDMEKQVVLSSSQNCSTSYGFVGSKNKD
HESEGNLQIKFSSSLKSVLSEGKLAGKSKLQAPRKICNKLEHAASDAENLKQLVFQESVK
RWKAEEDAMDAKKKADAAENKYLDEMKQRKGVEEALVKQKLECERMKEEHEKYTVEFPMV
RDQCLGLESQIRESEISGKELEEKIISAVELLKSFRAERDQKKLECDKAVLELENLNRSK
LKRTSALSGIQFSTFSLLEIGEATCSFDPSKRIGDGRYGSIYRGILRHIDVAMRMLPNDG
FLSQQMFEHGVEILSRIRHPNITTLIGICPEARCVVYEYLERGSLEDHLACRGKTPPLLW
QTRVMIVTELCSALIFFHKNNPPIFHGNLKPTKILLDANFRSKISDLGIFFLVAQKQAPN
ISQDCNSVYVDPEFLKTGALTRESDIYSFGIIVLQLLTGILASEIVKDVKHAMRKDKFEL
VLDFSAGDWPINQARTLARVALQCCERNPSKRPDLASDVWSVLEPLRKSCDVQTTCFQKK
ENSRPPSHFVCPIYQEVMKDPCTAADGYTYEGDAIRGWIDSGHTTSPMTNLKLSTCDLIP
NHALQYAIQEWLQHS
>Sgl07195 E3_activity/RING/RING 30.8 7.0
MASQLWEDHHVPPELKENLTELYPELTLEEALQHQESLYQSLTLGCVCQTARSSDNEPSS
SHGHSWAESSNSGSGGYDMALDEAVARSLQELDLEGEDDHVFIAEPFHTGSGNTETAAAD
TSASDAYQDDVDLDRMTYEELQSLGEAIGSESRGLSKTEISSLPCYTYKSSFFSKKVDIG
ECVICYTAYKNRDSLITLPCAHKYHKNCIEPWLVRSKICPICKMEVKLSFD
>Sgl07196 E3_adaptor/Cullin_RING/SCF/F-box 12.1 0.0
MGVGQSGLRSGLGELPESCVAEILGRLSPPEICQLAEVNKTFYGASLSDFVWETKLPSNY
EFLVQKLFHRRVDTLSKKDIFAMLCSPIRFDAATKEIWVDRRSGKMCMAISWKGMKITGI
DDRRYWNQIPTLESRFNVIAYLKQVWWLEVGGELEFNFPAGTYSLFFKLQIGKSSKSRFG
RRVCNTDGVHGWDRKPVRFQVCASNGQHAVSQCYLKEAGNWVCYHAGNFVVENHHLPMKV
KFSLTQIDCTHPKGGLCLDSVIICPSELADCLK
>Sgl07198 E3_activity/RING/RING 21.3 3.5
MEPVTEDSSNGVEENHSKNEYLMSDSGDDNKDDIDFEVEVLGDLENVETKPSFPVKEDSN
KVVDENHSENEYLISDSGDDSDFEVELLRDLEDVETKPSFLRFQEPHKGYKVMSEAEIRQ
CQERDINNISECLSITQAEAVLLLRHFHWNVDVIPEEWFNNEQELRIKLKLSDFPGFESF
DAKDMTCAICFGTFSQELIATALCGHIFCDTCWADYIRMAIEDGMASLMLRCPELSCTAP
VGRDMINMLAFDDDKDAYAGYFLRSYIEHNPKAKWCPFRCNCAVILEGDTSGSKVTCECS
NSFCFKCTKEPHQPISCAVLRNWQTESHVQSEIWSIGKTKSCPNCGTLVEVHDRHKRLEC
ASCNFQFCKLCLVSWLEQSEWEHVCSEGKFKQPDIEEEQVKEAQQRFNRYNIRLLQWETH
DMHMQADLEEIQILQNGQLKAIADKQGLTEADMSFVKDAWLQIIECKRFFEWACVYDYYL
KDGENEKQILFNYLTRRAEIILEHLYHRAFELITFLDIERPPEEFSTFRANLYSLTWVNK
NYFNNMAWAIENNLNMQTLCLVMESRMSRVNTSAPQKDGRKRPFSYSPSWDCAWCLFEND
ASAWSCVMCYHP
>Sgl07207 ULD/UDP/UBQ/UBQ_Other 36 0.1
MMRMRTKLTGLSPMNGNSNTANGDRHREVSNGDNRGVGGGGREAEGEGGPENWEMRPCGM
LVQKRVDGDQEPKPIPTIRVRVKYASIQHEIHINSHASFGELKKMLAGPTGLHHQDMKIF
YKQKERDSKEFLDIVGVKDKSKMSLVEDPLSQEKRYLEMRKNAKLEKAAKSISEISLEVD
RLAGQVAALESVILKGGRVAEKEVANLIELLMNELIKLDGIYADGDVKLQRKMQVTRVQK
YVETLDMLKIKNSTPATNGTHVPSENKQKISNGQVKSVRSKGYGQEKSSNSGKPPLPQQR
QRNSIGHSPLQPQAHKEQQSKNSTSGTVVTTQWETFENAPPLIPISTTSSGSATPKVVNP
NFPWDFE
>Sgl07222 E3_adaptor/Cullin_RING/DCX/DWD 93.1 3.8
MDFDANGGNKRVFHRLGNKQPQSHQFQQQKVCYHWQAGRCNRDPCAFLHTELPPQQRQNH
PSNQSFSSSTSTSYNGGSKRAHGLGGGGPQNDGFSSRKNPNFNNTWGRVGAGPPKKLERV
CNYWVQGKCSYGDNCKFLHSWSIGGSFSLLTTLEGHQKVVTGITLPSGDKLYTGSKDEHV
RIWDCASGQCVNAIPLGGEIGCMISEGPWVFIGLPNMVKAWNIETVTDMSLSGPVGQVYS
LVVGNDLLFAGTEDGAILAWKFNPATNCFEPAASLTGHTRAVVTMFVGANRLYSGSMDNS
IRVWNLETLQCIQILTEHTSVVMSVLCWEQFLLSASLDNTIKVWAATQSGNLEVTYTHTE
EHGILSLCGMFDSEAKPVILCSTNDNFVHIYDLPSFMERGKIISKQEIRAVQAGPSGLFF
TGDGNGQVRVWNWLTEPKKAM
>Sgl07336 E3_activity/RING/RING 37.3 6.7
MFIIVVASNSGIDLAIRSSSRIEVWRLAYLNRQNRWFWIKESKVVASNGWTLSSNLSENA
SRIVELLLRSHATITLLAVCVINAIVLFILSIKTIFFGVLYTPETQKLVERLVNYIIYKG
TFLPLIIPPTIFQAALWFTWLTVLCFLKMFQALARDRLERLNASPSATPWTYFRVYSALL
LVLTFDILWIWFCAAVSGPLVSSTFWLLFFEPLSIAFETLQAIVVHGFQLMDIWLHHSSE
EISDCERSKFLDTAAGSLWEWKSDVVRNLGFFLDMMTLLMALGHYVLIWWLHGMTFHLVD
AILFLNIRALLSAVVKRIKGFIKLKIALGALHDALPDATSEEIKTYDDECAICREPMAKA
KRLPCNHLFHLPCLRSWLDQGLSGIYSCPTCRKPLFVGRIESEASSHTRAVSSDEQLARQ
LSSGVDRVNTGDGGVFPNQNQNSAEVNAWRGAGADSSWLQPWPSQGLDGAGPSTATRSAG
LGRVQMMMRQIASVGETYAQNALEDTSWSLWPTNSSQATASNTAPAPVAHRFPAAAAAVH
RRSASQPANDSIANLLAMAETVREVLPHIPDEMIFQDLQQTNSVSVTVNNLLQM
>Sgl07364 E3_activity/RING/U-box 78.2 0.2
MEQKAAVENGKGSTSSRVIAVALNGGAKSKYIIRWVIDKFISEGNVSFKLLHVFPKITGV
PTPMGNLIPLPQVRDDVASAYKTEIEWQRNEMILPYRRMISQKKVPVELVLIEAEDVASG
ISTEIAQHGIKELVIGASSNGLFARRVKGQLLSSVISDCAPTFCTVYVVSKGKLEALRPS
KTETNGDVVECDSAATDSTNSSSRYTNSTFDPGSTYSDSPYSSPPGPVKQPEAISSAQNG
CSNSGTDSAESTSSQPSNTKIVDDLSSSVGTLTNQTSSLKTSNVDCEWITDQASTGLSYL
RPSDASSSKSQLASCESQENINEEIEKLKVELRHIRGMYNIAQNEAMDATRRLSDLGKLR
NEEALKLKQIGEKEEKAKELAKQQKERFEAAKREAVYARECAQRQVMQRRDAEQKAARDA
KERQKLKNVLGDPVYHYQKVTWDEIVSATCSFSDKLKIGEGSYGTVYKCKLHYSTVAIKV
LHSKEGANSKQFHQELEILSRIRHPHLLLLLGACPEQGCLVYEYMENGSLEDRLLRKNNT
PPIPWYERFRIAWEVASSIAFLHNNKPRPIIHRDLKPANILLDHNLVSKIGDAGLCTMLN
LDPSSISTLTLYKDTGPVGTLCYIDPEYQRTGLVSMKADVYALGMVILQLLTAKPAVGIT
NMVEDAIKEGRLMQILDTYAGRWPLKEAAEMALLGLQCAEIRRKDRPELKSILPILERMK
DVAEKARDSFAKNQVAPPSHFICPILKKVMEDPCVASDGYTYDRKAIELWLKDNDTSPTT
DFPLSNKNLIPNNTLSYAISEWKSKRRTQNGHYSY
>Sgl07403 E3_adaptor/Cullin_RING/DCX/DWD 33.1 0.0
MSYHDGGTLKSSSINGVKIYSLTGQQRSLATWLNPKKQRALRKDKDYMQRVELIQDLRFQ
TATTRIKASPDGAFLLASGIYPPQVKVFELRELSLKFERHLDAEIIDFQVLSDDYSKLAF
MCTDRSISLHAKYGAHYNVKIPRMGRDMAYDCWSCDLLCAASSPDLYRINLAQGRFLAPF
TTQSPALNVVSRSKLHGLVACGGEDGAVECFDTRTRSAVGRINAVSATDEDAEVTAIEFD
EEGGFQMAVGSSEGKVLIYDLRSSHPIRVKDHMYGSPILDIKWQRTLNSEHPKLISTDKH
IVRIWDPETGEGMTSIEPTGGAINDICVFRESGLILLALDSSQIPSYFVPALGPAPKWCS
YLENLTEELEENAQTSIYDDYKFLTKEELEKLNLTNLIGTNLLRAYMHGYFVDYRLYKKA
KAIADPFAYDAYIEQRKKEKLEKMHGERITIKRRLPKVNRRLASTLLEDEEAEKEIKDNT
DADAKKTSKKKKGLSSDILKDDRFADLFNNPVLPDCTLYTLS
>Sgl07416 E3_adaptor/Cullin_RING/SCF/F-box 13.5 0.1
MNSLCYVYLPENIIFEILLKLPPKTIIQCKTVCKQLRFLKEQFILPPYYLLCSYDWLFAL
HLNHSHHRQCITSKELENQALPLSSKSFELTSNKDVLLSTCNGIMCFYLKEKNNLCLWNP
TIDETRFVALPYESYWIRKFYFAGFGYASSIDDYKIVLAAKYARHTSNTSNDRRSLGVYS
LRRNEWRELDFDYYKSIAPEIYSGLGWRSGRQQSSNGIRMESIVVNDALHWVIDSYICNI
NMKFFLYKFDLVNECFEKVDVDLNKMISNIIVDGDNRLGPRQIEIGVIENRLVIYQLYSE
FRHSNPSNEFLVKRDVVKAWEMAEQYDYNSWKTKFRYVGDWDDIRDNHDLVRITGNGNVL
VIGGTYAEYESRLSFDQNSHKQRAQDVDFYAKHYVPSLVSPNNF
>Sgl07425 UBD/Alpha-Helix/UBA 36.2 0.1
MNGGPSGFNNAPVTRAVIISSAIFTIFFGLQGRSNKLGFSYLDIFQKPQLWKLIVSTYAF
TSTPEMMFGLYLLYYFRVFERQIGSHKYSVFILFSLAVSFFLGSIVLLLLKDPSALITAG
PYGLIFSSFVPFFFDIPVSTRFRVFGFHFSDKSFIYLAGLQLLLSSWSKSILPGICGIIA
GSLYRMNFFYIRRAKLPDFIVSLFSRLSWPSTGGTPSAPGTRTVSTAPPYAGRQVERNYP
APLAGTVEPSEDSVAMLVSMGFDLDSARQALVQARNDINVATNILLEAQSH
>Sgl07446 E3_activity/RING/U-box 27.5 1.7
MASSQNSEHETEPTQSTDPQLSISSSSSHVYMVGFVVAHIVGVQYYSGKISGREMVGLVR
EPLNIYDENAIKVLNTRGDQVGHIERNVAKVLAPLMDSNIVIAEGIVPKSPISSNKPRFK
ILVQIHLFARGEAFREIHSAILGGGLGFVSTREAVSFELSEAEVVKERRNCKDVKSVDEI
FENVGRKERVVVKLEPPKEVVITDLFDHQKEALGWLVGRENSDELPPFWEEKDGGFVNVL
TNFQMSNRPEPIRGGIFADDMGLGKTLSLLSLIAYDKYCCASVSVSGSGSASVGEISVNC
GGDGDNVEGSGGGKKSKGGRKGKRGGSSGSGNGSAARKKRKVGGVSEGVSVSLVSSNTTL
VVCSVSVMSVWMTQLEEHTRNNSLKVYMYHGVGRIRDVEELKKNDIVLTTYNTVSIDESQ
PDDPLHRMEWKRIILDEGHTIKTAEAKQSRAVTALNGKRRWVVTGTPVQNSSQDLFSLLA
FLKFEPFSNKIYWNSLVHRPLVQGDEKGLERLQVIMATVSLRRTKEQELFKLPLKSLQTC
YVELMPEERELYDRMEEEAKQFVKKYVNDGTVTHNYSTVLSIILRLRQICTDVALCPHDI
KSLLLPDNIQDVSNNPELLEKLLTLLQDTEDFDCPICISPPSDVVITCCAHIFCRACIIK
TLKLAKSKCPMCRHPLSESELYSAPPPAEPLDSTNTSSSPKPSSKVSVLVKLLSENRGVK
SVVFSQFRKMLLLLEEPLKAAGFKTLRLDGAMSAKKRKQVIHDFGVCGDDSPTVLLASLK
ASGTGISLTAASVVYLFEPWWNPATEEQAMDRVHRIGQKNNVKIVRIIARNTIEERVLEL
QEKKKELAKGAFGKKEKQETNVGDLCRLISLSA
>Sgl07450 E3_activity/RING/U-box 27.5 1.7
MASSQNSEHETEPTQSTDPQLSISSSSSHVYMVGFVVAHIVGVQYYSGKISGREMVGLVR
EPLNIYDENAIKVLNTRGDQVGHIERNVAKVLAPLMDSNIVIAEGIVPKSPISSNKPRFK
ILVQIHLFARGVAFREIHSAILGGGLGFVSTREAVSFELSEAEVVKERRNCKDVKSVDEI
FENVGRKEGLCVKLEPPKEVVITDLFDHQKEALGWLVGRENSDELPPFWEEKDGGFVNVL
TNFQMSNRPEPIRGGIFADDMGLGKTLSLLSLIAYDKYCCASVSVSGSGSASVGEISVNC
GGDGDNVEGSGGGKKSKGGRKGKRGGSSGSGNGSAARKKRKVGGVSEGVSVSLVSSNTTL
VVCSVSVMSVWMTQLEEHTRNNSLKVYVYHGVGRIRDVEKLKKNDIVLTTYNTVSIDESQ
PDDPLHRMEWKRIILDEGHTIKTAEAKQSRAVTALNGKRRWVVTGTPVQNSSQDLFSLLA
FLKFEPFSNKIYWNSLVHRPLVQGDEKGLDRLQVIMATVSLRRTKEQELFKLPLKSLQTC
YVELMPEERELYDRMEEEAKQFVKKYVNDGTVTHNYSTVLSIILRLRQICTDVALCPHDI
KSLLLPDNIQDVSNNPELLEKLLTLLQDTEDFDCPICISPPSDVVITCCAHIFCRACIIK
TLKLAKSKCPMCRHPLSESELYSAPPPAEPLDSTNTSSSPKPSSKVSVLVKLLSENRGVK
SVVFSQFRKMLLLLEEPLKAAGFKTLRLDGAMSAKKRKQVIHDFGVCGDDSPTVLLASLK
ASGTGISLTAASVVYLFEPWWNPATEEQAMDRVHRIGQKNNVKIVRIIARNTIEERVLEL
QEKKKELAKGVFGKKEKQETNVGDLCRLISLSA
>Sgl07479 E3_adaptor/Cullin_RING/SCF/F-box 13.9 0.0
MSDINPGFGPQLWSEILKFLPVKVLGQCMCVCKSWKTLIKSSTFVAAHIQNYAQSEANSC
LLYRQFTNAPENHEQYTVFLDSAQKESVPKPLHTFTCPFISHKYFRVVGSVLGLICLSDD
LFGYSYLVIIWNPLLHKYIRLPIPRVTYLTGVSHISAFGFGFDSKKCSHKVVRVNYMRDE
KALDTTPPFVEVYSVHEGSWRRVSANNVVDICICDYWWSQCFLNHAVHWVAWERDGKTRA
FYRNCLLLFDVEEEKFKKMKLPEALAKEFTMNLRVSECGAKLSVLHSVQKGGTLGNEMER
CEIWVKEEYNVGSSWCKMYCIEKNSSPRLGWIQCLRRNGDVLGFTKKGELMSYDPLMKQI
NGLGVRGCWRSWSTCSYTESLVLLDKKNDVGTYDVARGQRKKFEILVRSNGSLDMGEKNT
DNEDVEHEADKHGFIINHREKAFLLDQMRKFDAGRMTEDPSDFLAMAGLDFGDLKSMAES
YVADHR
>Sgl07538 E3_adaptor/Cullin_RING/DCX/DWD 33.9 1.9
MLRLRAFRPTNEKIVKIQVHPTHPWLVTSDASDHVSVWNWEHRQVIYELKAGGIDERRLV
GARLEKLAEGESDYIGRMSLIEKESEIAMGKPTEAIRGGSVKQVNFYDDDVRFWQLWRNR
AGAAEAPSAVSHVTSALNSLAPATKGRHFLVICCENKAIFLDLVTMRGRDVPKQELDNRS
LIMEFLYRSTAGEGPLVAFGGSDGVIRVLSMITWKLARRYTGGHKGAINCLMTFMASSGE
ALLVSGGSDGLLILWSAEHGHDSRELVPKLSLKAHDGGVVAVELSRVSGGAPQLITIGAD
KTLAIWDTISFKEMRRIKPVPKMSCHSVASWCHPRAPNLDILTCVKDSHIWAIEHPTYSV
LTRPLCELSSLVPPQALAPSKKLRVYCMVAHPLQPHLVATGTNIGVIISEFDFRALPPVV
ALPSPPGSREHSAVYIVERELKLLSFQLSNTANPSLGSNGSLTESARPKDSEALQVKQIK
KHISTPVPHDSYSVLSLSSSGKYLAVVWPDIPYFSIYKVSDWSIVDSGSARLLAWDTCRD
RFAILESTVAPRMPVIPKGGSSRKAKEAAAAAAAAAAAASAASSGSVQVRILLDDGTSNI
LMRSIGGYWFAWRCTSGIAYRTSRRVSAVAATAISTVQSMPLSGFGSGASSFNTFDDGSG
SGPSSTQNFQLYSWETFQPVGGLLHSQNGQLGMKQYLGDVAIPYATSAVWHRRQLFVATP
TTIEVVFVDAGVATLDIETMKMKEEMKLKEAQARAVAEHGELALISVDGPKSDTNDRIPL
RPPMLQVVRLASFQHAPSVPPYLTLPKQSKIDGDDSGLPEDRRANENAVGGGGVAVAVTR
FPMEQKRPIGPLVVVGVRDGVLWLIDRYMRAHVLSLSHPGIRCRCLAAYGDAVSAVKWAT
RLGREHHDDLAQFMLGMGYAVEALHLPGISKRLEFDLAIKGNDLKRALQCLLTMSNSRDI
GQETSGLDLTNLLNVAAKKENIVDTVQGIAKYAKQFLDLIDAADATAQSEIAREALKRLA
AAGSVKGALQSDELRGLALRLANHGELTRLSTLVNNLISLGLGREAAFSAAVLGDNALME
KAWHETGMLAEAVLHSHAHGRPTLKNLVETWNKMLQKDIEHTRTTKTDATAAFLASLEDP
KLPSLGDTGKKPPIEILPPGMSSLSLSISAPKKPLPATKALQQEPGKQLLLEAPPTAAPI
NGATPPAADSGESTVPPPVDSNQSGAPPAEPSQSGASPAEPSQPEATPPESSQPGATPLE
SSQPGATPPESSQPGAAPESSQPGATPPESSQPKEASSEAEAPSTEVSDQPKLEGTTSAD
KSEAGASNQVEYSQLEASKPVDSSQSGAPLPANLNQPEASPATIVSTQPILDSKAFELQL
LGSTGPEVTKPSSSRSVFADLEQLM
>Sgl07547 E3_activity/RING/RING 33 13.3
MEEEFQFHNHIPTNCLRNYFTSTFSRCFSLTPCINGGYSELRIEDDSDDGSLGDQAYCKP
FIVLDVIWNLGFVLVSCFMLICTISEKPSTPLRVWICGYALQCLFHVGFVYIELRRRNHG
RVPLPESQSHLSYSFVKRLESANTIISSFWWVFGFYWIVSGGQSLLQDSPRLYWLAVVFL
ALDVFFMIFCIGMACIVCLAVFCCIPIVAIAYAMTIREGASEDEIRQLPRYRFHQSYTPL
GSVNATDELTLHFDNSECCICLTRYVEGSELCNLPCNHNFHYGCISRWLRINATCPLCKF
NIKAKGDALV
>Sgl07553 E3_activity/RING/U-box 29.3 2.4
MAVYYKFKSAKDYDSIAIDGHFISVANLKERIFESKHLGRGTDFDLVVTNAQTNEEYLDE
AMLIPKNTSVLIRRVPGRPRMPIVTQPDEPKVENKIEDDSLVKSNFTAVDSSVYRDYDGT
EMDDEFGNDLYATIPEMTPGQSNNQMQDLVPPSKADEDSKIKAFIENSGFDWQRQGNDGF
GPGRGFGRGGRGGRGFGRGGGLEKKAPPQGYVCHRCKVPGHFIQHCPTNGDPNYDVRKVK
PPTGIPKSMLVATPDGSYALPSGTSAVLKPNEAAFEKEIEGLPSTRPVGDLPPELHCPLC
KEVMKDAVLTSKCCFKSFCDKCIRDYIISRSICICGASDVLADDLLPNKTLRDTINRILE
SGNSSADNGGSALHIQDMESARCPQPRNPSPTQSAASKGDQMLPPRTEGTSNLKESVDGI
KPSDASQQQVQQQISDKGKITKVPDVSEATHESASVKEPASQGSALPVEEEVQQKVATSE
AGKKKKKKKKMPLPVNAPDMQWMGGMPPGMDGYNNNNMGPSAFNPCWPGMQPGMDGFMNP
FGGNMPFNMGYGPGPMDMHFGNVMPPDPFGNVMHPDPFGPQGFMMHGMGMPPMRPPPPQR
DLAAEFGMGMNVRPPLMSREEFEARKAEVRRKREMEKRIESREPPKDRDYSREVNSSANL
HAMKSKPKPPPASRSPSQDRYDSFRDRERARERVSVDRDRDRDRDHDSHQRRTTTHSRHE
RVSPERTRRESRDPEVPRPTLKRKSEHHERDHSHEREREREHRDHRSHTKPSSSKPVPSS
DVVSPSSDKKKASVFSRISFPEDEPVKKRKVSAEPKPKPKAVSKDHEPHHHKAAASSSMA
NGHHETSRKSVAASDMDCESSDDERHFKRKPSRYEPSPPRREEWMSVADEEDGRRHRKHR
>Sgl07557 UBD/UBC-like/UBD_UBC 116 0.0
MATNENLPPNVIKQLAKELKNLDDTPPEGIKVNVNEDDFTTIFADIDGPAGTPYENGVFR
MKLILSSDFPHSPPKGYFVTKIFHPNIANNGEICVNTLKKDWNPTLGLRHVLLVIRCLLI
EPFPESALNEQAGKMLLENYEEYARLARLYTGIHAKPKSKPKQGAISESTTALNVDQKNN
SSAQTANQENTGASTKAKSLQDQPVAVGTVASALPLNENGAVGSSTAPTVAAAASVVQKK
DGVKAHAEKKKIDARKKSLKRL
>Sgl07593 E3_adaptor/Cullin_RING/SCF/F-box 19.9 0.0
MKTNLLDLPQECLSQIFSLTSPLYVLRCSLVCKLFNSVANSDLVWKNLLPSDLHPLVQDL
STTPTKHLVLLLCRSFILLGDRNMSVSLDECTGKKIYVLGARTLTFAQSDCWLWESPLPE
SRFLEVAELFGVTELHITGKISTKLLSLNTTYRIHFSFMLQPDSSGFGKHPVRVFVSKID
ASGACLGGSQDNSKTFYLKAPVKGKRGDIFDDDTCVDTFDKPDDVETEDTFRHCSDAPRW
LKIDMGKYFHKEDSDVAMLEMTLMGTEIGLRKSGLVVHAIELQPVD
>Sgl07598 E3_adaptor/Cullin_RING/DCX/DWD 29.7 0.0
MVVRAEKIVPDIEQDGEELDANVKKFLRGEGANLEALQDKKLKGQLADKEKLYKRSAKAA
ASVEKWLLPSEGGYLEPDPDSIEKTWRVKQVDIGKEVDILSLKNQFDMVLPELGPYNLDF
TANGRYMAIAGRKGHLGVLDVKNMSLIKEFQVRETVRDVVFLHNELFFAAAQKKYPYIYN
RDGIEVHCMKEHGAVSKLQFLKNHFLLASINKLGQLRYQDITIGEMIANFRTRLGRTSVM
QANPYNGVIGLGHSCGTATMWKPTNPNPIVKMLCHQGPITALAFHPNGHLMATAGMEKKI
KLWDLRKFEVLQTMPGHAKSLEFSQKGLLAASTGSFLQVMRDVSGSQNYSRYMTHSMAKG
YQIQKLSFRPYEDVLGIGHSMGWSSILIPGSGEPNFDSWVANPFETSKQRREKEVRSVLE
KLPPEAIMLDPKKIGTVKPQRKKKLTRKEREEEMEAAVEAAKGVELKYKMKGRSKAGKRA
KKRQELVEKVKKQFIEQNAKEDEEVSHKKRQRTSEEVVELPKSLQRFAKRKAD
>Sgl07608 E3_adaptor/Cullin_RING/DCX/DWD 31.1 2.4
MFRCRRIMSQQQVDEYDYMADENEVADFIDEVDGEFYARDDGNIGMEEYDLLTKVTDTSA
ANARRGKDIQGIPWDRLNITRDKYRLTRLEQYKNYENVPSSGDSIDKEWKSKEKGGNYFE
FFYNSRLVKPTILHFQLRNLVWATSKHDVYLMSNYQAMHWSSLTRNLSEVVNFAGHVSPS
EKHKGSLLEGFTQTQISTLAVKDNLMVAGGFQGELVCKRLDNQGISFCARTTYDDNAITN
AVEIYNSLSGCYHFMASNNDCGIRLYDMERFQLMNHFRFPWPVNHTSICPDRKLIAVVGD
HVNGLLCDSQSGKVVSTVQGHRDFSFATAWHPDGRVFATGNQDKTCRVWDIRKLSESVAV
LKGNLGATRSIRFSSDGNFMVAAEPADFVHVYSTKANYERRQEIDFFGEISGVSLSPDDE
CLYIGIWDRTYASLLQYNRKHAYQYLDSFV
>Sgl07719 E3_adaptor/Cullin_RING/SCF/F-box 17.7 0.6
MANSNKRTNSTPELAKAVVARVPGAGDDRRTLAGCVKRPRRSTEENDAASSRSNCFPRDI
AFSILQLLPATFLSNSGRLVCKQWNEIISDPLFVRAHTQLHLLLPSSLRIFVQDVDLRYA
KHMQAYYLRTHDADDNDTDTDIDIDIDTDTDSDSGSESDATKLMLPFPATILDSCNGLLL
LHHVTIRKELRVVNFATREIVTLPPLLEAGVRVLVRPYAALAYVPSSGQYKVVYVSLVSN
SKRAAYLRDAQDALAHSRIHKVKVLICTLGVDKTWRTIDFGKDITLMGKGEQSLLLCQPL
STTAGYIYWLNFDHYMFGLALDVDAETMHQFTAPKDYKLKGIHTFYSIKMDTGVALVGYR
RNYRNEDWKVWEMIDPKNGTWGTSISFNTDHMQLILLDQDYHMIRGKVPFSISLRTGDLW
LYSEVDGRYALVCYNLKTAKLRFIDFVPYVEWPNRHALPQLHVNSLISLKNL
>Sgl07727 E3_activity/RING/RING 35.6 5.9
MAPVRYCSREDLLSSLVCKDQGVAQGPFSDDDDDDSSSDGINYTRATIVFAIIAVVILVI
YFSYDFLYVHIYLRRIRNNIHGNNRPAKPKGLDPNVLKTFPVFVYNDEAEAEAARPGIAL
EDCAVCLATFEKDETLRMLPKCGHVFHVECLDPWLVGHSTCPVCRANLVPQPGDVARTMG
GGVEARRDEVVVDIREQYEVVEVNRPVEVNGTRVVCQIS
>Sgl07745 E3_activity/RING/U-box 32.4 0.1
MGDRTDDLMNLDLNLGPGAPPSPVLGPGIGPSSGESVNVDGWESSYVREALNLRQRTRHL
WRWRRQVHLPLEPHSLRLMVESDGNGGDPGGGSGAEGEDNGGTLQAGEGSVTAERRNYEA
VKTCENNVIAVENGSIAAKEDVEKPNSEEGSFFDCNICFDLAREPVVTCCGHLFCWPCIY
RWLHIHSDAKECPVCKGEVTLKNVTPIYGRGTYVHEPEEDAGIKVPLRPTARRVESLRQS
IQRTASSFRMEEMIQRLGARFELTRDFFQNPNGVDGDTDLSSRVSFLNRFMTTRALRREQ
NPPIPPEEVVVDLTQERPEVPARRLPPLTYRRGQLHRNAAAAAAAYSARANAPDRFELWT
SSARSQDPQPPSVDDRDSFSSIAAAIHGESQTVDTAVEIDSLVSLSTSSSRRRHEPSRAS
DVDSGDSRAPRRRRLN
>Sgl07817 E3_adaptor/Cullin_RING/DCX/DWD 112.9 13.5
MSQVNQSSPSVILATASYDHTIRFWEPQTGRCYRNIQYPDSQVNRFEITPDKRYLAVAGN
PHIRLFDINSSNPQPVMSYDSHTNNVMAVGFPSEGSWMYSGSEDGTVKIWDVRAPGCQRE
YESRAAVNTVVLHPNQTELISGDQNGNIRVWDLTANSCSCELVPEVDTAVRSLTVMFDGT
LVVAANNHGTCFVWRLLSGTQTMTNFEPLHRLQAHKGYILKCLLSPDIGGSNSPKRYLAT
ASSDHTVKIWNVDNRFTLEKTLSGHERWVWDCVFSVDGAYLITASSDGTAKLWSMISNEV
IQTYQGHHKAVVCCALNDGAEVSS
>Sgl07928 E3_adaptor/Cullin_RING/DCX/DWD 131.1 15.0
MEIEEENPSSASAAEPTASVVDTEMLATQAVPDPATAIAGPESLSLATTITSVAPPLVIP
GAVPPSVPPAVTLLSAPPSVHVPPIASLPVVPPVVPRPLAPLPVRPPVLKPPVVQNGEMK
ESESDDEDNDDQDSGKGEHGSTAEYEVTEESRQVRERQEKAMRDLLMKRRAAALAVPTND
MAVRARLRRLGEPITLFGEREMERRDRLRMLMVKLDDEGQLEKLMKAHEEEQEAAATKDE
VDEDMLQYPFYTEGTQELLEARKFIAQFSIVRASQRLQRAKRKRDDPDEDEDAEVDWALK
QAGTFVLDTSEIGDDRPLWGCSFSKDGNFLSTCSSTGVAKVWSMPQLKRVSALKGHTVHA
TDVAFSPVIDNVATASADRTARLWNTDGTLLRTFEGHLDRLARIGFHPSGKYLGTASFDK
TWRLWDVESGAELLLQEGHSRSVYGLAFHRDGSLVASCGLDSLTRVWDLRTGRSVLALEG
HVKPVFGVDFSPNGYHLATGSEDNTCRIWDLRKKKSLYIIPAHSKLVSQVKFEPQEGYYL
VTASYDTTAKVWSSRDFKLIKTLSGHESRVTSLDITGDGQSIATVAHDRTIKLWSSTVPV
EENSMDVG
>Sgl07933 E3_adaptor/Cullin_RING/DCX/DWD 99.4 9.7
MDHKISKLSNEEDEDQLSIDKSPSFHHFTLQSSPGFHHFTLPSSPLPPQSPESLWSQSPS
CTLHSSPFSRSHSRSPLYYSCISSLRHKDQLYSIAVCGDLVLTGSSSRRVHAWQLSSHDF
LAKGYIQASSGEVRAMVSLGNNMLFTSHKDHKIRVWEIGNGNNFRPRKVTTLPNIKNFIV
FRPIVTPQHRLIKSKTTSSQHKDTISCMAYSHVEGLLYTGSYDKTVKTWRLNEKKCIDSF
IAHNNNIHDIVINQKNGYIFTCSSDGTVKMWLRVIGEFSHALIKVLTFHKNPIYAMALSI
SPASQNQNSFLYYGSFDGSINFCELETLSCQCNNHERRVIQGHQFSVLCLVALENLVISG
SEDSTIRIWRRSSGERRVVSHECVAILEGHRGPVRCLGARLQDKSTTSLLVFSTSLDQTF
KVWRVKHNVQEINNNLVDRRSNADDGNIKEGSNSLEFEFVERSPVLSQEWVKKRGSISQC
S
>Sgl07942 E3_adaptor/Cullin_RING/SCF/F-box 17.3 0.0
MFSSYNNNGSMQNSDDNNNLIKSPTWEVLELISHHLDPQTLAIASCVSKTWSTCFSSDHL
WAPLCTTHFPSLTSSLSAVAATSLPRCRLYGLGYSAALRRRPKKPRKPRLDPNRLLFAVS
VHFPAGEVDVLKSCDAMRWDPHGLFRFDLEVAERREWTVEELKAVKVTWTVAEREWKAVF
TVAEDASGNLSSAVDGLFSKELPSPGCCSSSMSSGLVADIRFGLKDQDGHLFSWIKGSRV
SKIEKVSVGIMDVRNWRHISLDDGLLYLEHFLQV
>Sgl07969 UBD/UBC-like/UBD_UBC 126.6 0.1
MTLLSCLLSSFKRHKKHDSKRSSSGSSMGKSQTIGTITRNRVYSEMTRMSVQNVVVSHWS
YGLVDVHDPFNLQGIIIGPSDTPYDGGVFFLSINLPHDFPFKPPKIKFRTKVFHPNVTSD
GTVDIDILSNEWTPIYTIDNLLMLMCCFLSQPYNVLDSSNYVCHLYSNHRKLYNKIAREW
TFKYAMI
>Sgl07972 DUB/USP 269.1 0.4
MNLESSNSTSMDVDASCSVQSEGYSNLERGVNVTVEHEDDADIDQMPMVCASSKYEPPKP
FFTEDEREMNPLELREQACKNKEEEERRMEKEKGKPEGGRKVRLPPEDLATTSKPSAPPV
EEKKEIITGKRVSKKAARSALKEKDKKVSTSSSKTVSQEGNVNYVIANDGPVTKKEKKAC
VHLEKGVNLGIVCSKIESAESTGCEYCREGVNDRKAGKGKGKHGKKKGASDSRAKGKATW
ICLQCGHFSCGGVGLPTSPQSHALRHMRQNRHPLVIQMENPHLRWCFSCSTLLPVNKVED
NGEEIDVFLDIVKLLKKQSSKSAKAPSVDVEDVWFGSGSVLSEVKAENKAVTVANGKDSY
AVRGLVNLGNTCFFNSVMQNLLAMDSLRDYLLNFDGSMGPLTSALKKIFVETCSDAALKN
VVNPKSLFGCVCSKAPQFRGYQQQDSHELLRYLLDGLSTEDMSAKKKEITSAVTATFVDT
FFGGQTSSTVCCVTCGHSSVVYEPFLDLSLSLPTKKPPSKKAQPVFRAKKTKPPPKRGGR
TRPKLNKNGDLGPALSGCNTSANVEASSGIKDDMRPVANGCNTLITAESASSMKGGSLSC
ALSADLVDTNNGFQRNASVTQDDYTCAQVPQFAAQDDGMPWLAYLEPTSQGEGAQDVDSF
SWLDFIEPVSSLDGRNLAVEDEDLLGSLHGNHESDSMQLTAKSSVEDNLAKVSGMKFDNQ
DVSVPNTAKSGGEASVPPADMVPKVESIVDDWGDERPVMVQDNEVLLLTYKEDGPMEGEG
MGIDADMPSSSVVDGEDTLCFGGLGDLFDEPEAVESETGVSNTLVNESLGNGYIAGNNTE
SDPDEVDDTDSPVSVERCLVQYTKPELLSGEHAWHCENCSKLLKEERQKVRKNQKKAALI
QKNMHSDVCCSSKVLQAKSHLCIDSSASILAPCNNGNSDTDENLKKFEARDTNRLCPCLP
QEEEERLVRETAHLTASASGVCFGPCDESNLNGRSVDSHAVFNNHIPIECSGLSEENELV
EEEEDVDLKCVKVMRDATKRILISKTPPILTIHLKRFGQDTRGRLSKLNGHVVFKEFLDL
RPYIDRRSTEKDKCIYRLVGVVEHSGSMRGGHYVAYVRKGDRQSGRSEVQNRQGHSVWYH
ASDAYVREVTLEEVLRCEAYLLFYEEVKLC
>Sgl07978 UBD/Alpha-Helix/UBA 37.1 0.1
MSGVSLRCGDCGVLLKSVEEAQEHAELTSHSNFSESTEPVLNLVCSSCGKPCRTKTESDL
HTKRTGHTEFVDKTSEVTKPISLENPTSSTPMDVDASGSSQSEEMVVPDVDKQLLEELEG
MGFSKERATRALHCSGNSSLEGAVNWIVEHENDADIDQMPMVPASSKNDPPKPSLTEEEK
KVKLLELRERARKKKEEEERKMEREREKERVRIGKELLEAKRIEEENERKRLIAFRKAEK
EEEKRALEKVRQKLEEDKAERRRRLGLPAEAPAAAAKPSAPPVEEKKLGLPVKPVTKAEK
MRECLRSLKKNHMDEDARVKKAFQTLFTYAGNVVKNPDEEKYRRIRLSNQAFQDRVGGLK
GGIEFLELCGFEKIENGEFLFMPREKVDEAVLNSAGKELQSAINNPHFGIL
>Sgl08036 E3_activity/RING/RING 30.5 11.0
MMSSISFIVMLLIMIIIPTIIYTFFFLINCPPNPFHFLRRNRLNDNNNARRSKIANDEDD
EGDGSNKDKTNNNIELVVASSENLVKETECPVCLSVFVIGEELRQLKICKHLFHRSCIDK
WLSTHCNCPVCRAFVRNHAKNMKEDQRNSSNNNRVFASRNMDRDDFWQGLPDSAGLV
>Sgl08094 E3_activity/RING/PHD 37.6 5.3
MAIARTGVYVDDYLEYASTLPAELQRLLNTVRELDERSQGMINQTRQHTKFCLGISSQSS
RKGYNEENEEEEDDDDALERLRKEIDRTQDNALSLCTEKVLLARQAYDLIDSHIKRLDED
LNYFAEDLKQEGKLPLDEPTILPPLPMVTAPKPERQRGGYGMPQSRRFSYRDRYWDRERD
KDSELMPPPGSLKREFPVPVDVDLPIDPNEPIYCVCHQVSFGDMIACDNLGCQGGEWFHY
ACVGLSPETKFKRKWFCPTCRELPQFRP
>Sgl08095 E3_activity/RING/PHD 38.3 3.6
MAIARTGVYVDDYLEYASTLPAELQRLLNTIRELDDRSQGMINQTRQHTKYCLGISSHSS
KKGYNGEGDDAAIEKLRKEIEGVQDNALSLCTEKVLLARQAYDLIDSHIKRLDEDLNYFA
EDLKQEGKLPPDEPAILPPLPIVTAPKPERQRGVYGTPQSRRFSYRERDWDRERDKDSEL
MPPPGSHKKEFPVPVDIDQPIDPNEPIYCVCHQVSFGDMIACDNEGCQGGEWFHYACVGL
TPETRFKGKWYCPTCRDLLQCRS
>Sgl08131 E3_adaptor/Cullin_RING/SCF/F-box 17.9 0.1
MENEEETKKTKNSVCSTYLPQEVMFEILVRLPITMGSETLPRCKAVCKQWYSLITDPLFT
RTQYHFYKNQFHLPSWCLLSAHVSSFVVHLNRNEFRYNVTTKDFVDHPIPVSSSHFKLSY
GRDVLLSSCHGILCLFLEDKNKLCLWNPTIDEVRFVSLPYEINRFYYVGFGYASSIDDYK
ILFAVEYTAGHPGTNCKSVSVYSLRRNEWRELDFEYCNSILTELELYLGLGFQTSTDHRN
AMRVESTVLNDALHWILVPNIYNKNIKALLYKFDLVNECFEKVVDLNSIDILIDDDDDEL
TPIQTEIGVSENNRLMIYKLYYEEDISKTMAMKRDVVKAWEMVDQYDYKSWKTKFHYVGI
WDGMSDDHDLVQITGNGNVVIIGGKFAENDEISLQVLQNDDLDFFAAHYVPSRVSPNKF
>Sgl08231 E3_adaptor/Cullin_RING/SCF/F-box 18.2 0.0
MAKNGLMISEGGKKKISKMMMMKSRKRVKIEKRYKKEEENENENDPMEVLGEDIMMKIMG
NLDARSLARSLLVSHSWFFLSSSDSLWSPLCKQLWIGKAHIPRWSKARGLSKLASYSRAV
TDSKRIRIMKEDLCDHAWDFHFTKEAPEYWKNLDPYWGGLGPPMHRYFHSDGSQTADPED
KVWGGHECSYTIVTSVVGDGKIRDNYVRINRWPRLVVSRRDDWGWEMSNVIFAYSSIPDA
DKGGGTGPMLKIC
>Sgl08283 E3_adaptor/Cullin_RING/DCX/DWD 41 0.3
MRDPMWVDDANAPSTSNPLPRIHESCSTAKRSGNNVFNLLARREIAPRTKRSTKRLWGES
SERGFDAGCHIFEAGRDSRRSLISWVEAQSLRHLSAKYCPLVPPPRSTIAAAFSPDGKTL
ASTHGDHTVKIIDCQSGNCLKVLSGHRRTPWVVRFHPTCTGLLASGSLDHEVRLWDANTA
ECVGSRDFYRPIASIAFHAQGELLAVASGHKLYIWHYNERGDLSIPTVVLKTRRSLRAVH
FHPHAAPFLLTAEVNDLDSSDSSMTLATSQGYVQYPPPTVYVANVNASEELPVTSLPLLI
WPLLPRNDGRMSFQHSDGSEGPNIVQQRVGPSSSVRLLTYSTPSGQYELLLSPVESSDIS
SVPDVRPDGQSAEMEPSAPESVVDAMETSDVQPEERNTQLFPFGDPAYWDLPFLQGWLIG
QSQAGQRMIRPVNSNSHELSSQSEMLNQDPVAAPAMQMGTSYTRASSRSTARHRSSRLRA
AVSTSGAEGAAPQDQEDPQPVISRIQSELATSLAAAAAAELPCTVKLRIWPYDIKDPCAH
LQADKCRLTIPHAVLCSEMGAHFSPCGKFLAACVACMLPQVEGESEIQMQANHDASGAAT
SPTRHSIPAQPVMYELRIYSLEEATFGLVLASRAIRAAHCLTSIQFSPTSEHLLLAYGRR
HNSLLKSIVFDGETTVPIYTILEVYRVSDMELVRVLPSAEDEVNVACFHPSVGSGLVYGT
KEGKLRILHFDSSSNLNCTFSCFPDESPITCFRMLISRIVLTYRHTVKLIRTTMTDSKAI
GSSWDEFSFSSLKCVVIRFLLYHAYTEVVMWWMQFGGIGAALGPPPD
>Sgl08366 E3_activity/RING/RING 28.6 16.7
MEDDVGKHRDEVPQSPRMFVSDSKGYALSGRIMLSAIIILFGVVVIMVCLHIYARWYILR
ARQRQVRRARRRTHLVFYIEPDGSNVNSNGVPVQSRGLDASVLKSLPILTFADVESEGKV
EALECAVCLSEFEEAENCRLLPKCNHCFHVECIDMWFHSHDTCPLCRAPVDSGDVAAPAV
ENPPSEEVVVEVGELTQSQPAELTQEMGSSQGEVKEESLSTSSSSLSTRKGLDLAGVSAI
EVPRRSHSFCFSGSNLDESGPSRSPGFKSPTSRIMSLKRILSREKRSPLPSPSGVGSSCC
EIDIESGRVDTPSQWLTPR
>Sgl08511 DUB/ULP 158 0.1
MKTDLFLWGTVRQPWLRDEPDCYRCSTQIDTHIAKKRRILCVTSPSKVIATPPSVVSRLS
RYPKPEKLPREVHAPCRLNRVGFQSGRLKREDSGIREKKLIMGNVLYRGYEKAKTNVFGV
LRFVKVDKNTEVIDLDAEPKKDGISKDWGEVEIVEDGKEVRSPVLDDHKAVDSDGSVLKT
NELGRKVVQNDVIEETLVVSDLTNVEDAGKDLGLRSLGREAYEELLSKVNRKYTTNLSSL
GFQIGSYEAQLQSLRSLHKEKEKKKSEELKKPGEDLLREPFVPLTEEEDRDVMRALSNSN
RRKILVTHENSNIEITGEILQCLKPGSWLNDEVINLYLELLKEREKREPKKFLNCHFFNT
FFYKKLIGGRNGYDYKAVRRWTTQRKLGYGLTECDKIFVPIHKEVHWCLAIINVKEKTFQ
YLDSLGGVDSHVLRVLARYFMDEVKDKSGQEINVSSWKEEYVEDLPEQHNGFDCGVFMIK
YADFYSRGLGLHFSQEHMPYFRRRTAKEILRLRAD
>Sgl08517 E3_adaptor/Cullin_RING/BCR/BTB 26.6 0.0
MAEQQQQQNRCNSLVEQDHHHNYCMKMSVSMSQPQHQQSEDNDPSSVELRAVDCNLASLC
DHIQSQGFNNGVFSDIVVNAMGSTYHLHRLILSRSSYFRNMLHGPWKEASAPVLSLQIDD
NNVNSEAIAIALAYLYGHYPKLNDNNAFRVLAAASFLDLQELCAICTDFIITELWTSNFL
AYQVFAENQDYGMHGERVRNACWGYLCQSGFLELKEVLPSLSCQTLHALLTSNELWIPSE
EKRFELALYTLLKKSALNKAETEEKQSASLETGLTDHCHSSDNKGKTIIDACCTRNSEAD
MGRVHQLSSSEPNLGAAYPNNIEQSSLLTYYSDSDRSRPSSSYVRMPVSFMANGQGGDGA
LVEGPSEESICCQFSNSNWISGNDSRECSSSSINSSCNEIMPDEWGRNDLAFPWGGRTVG
RRQVKSYGKGNCGLKGEEYGTFISVFEGGSVLYCNMSFEALLDVRKQLEELGFPCKAVND
GLWLQV
>Sgl08680 E3_adaptor/Cullin_RING/DCX/DWD 20.3 1.1
MHSHHLLILFCKGPNPRPLSTTQVHSFLFQLLKGVAHCHSHGVLHRDLKPQNLFLDKSYT
HEVCNLNLCCDFCVILELCVIAEFWKLQIVTLWYRAPEVLLGSTHYSTGVDIWSVGCIFA
EMVRRQALFPGDSEFQQLLHIFSFGTPLLTVYFFSSFVLLPNESLLGTPTEDHFCLFQIV
VWKLIRQHGTLPITSAEQKPDVMSTLVDVHSQECLEYEAEIVSKLAGHQGSIFCLSWSDD
GSKLVSVSDDRR
>Sgl09020 E3_activity/RING/RING 10.1 5.2
MDTSWIDLRPSNPTFYNGCMEFLELAKETQIEGKTRCPCNKCKLSKWLPVNDVGGHILFH
GFYKNYRNWIFHRVGEESNIHQSLGEQSNVIGRDDMEGLLKSMFRANNPHSIHEPIEDPF
DESDFRKDGLHDIDVESGVAHEDDDCDEFQYENTNEEAKFRRLMDASQEALYEGCSTFSK
LSFLLHLFHLKCLYHWSAESFTKLLELLIDAFFQIKEFPSFYYEAMKWKAVKGKEGDASG
QGKESCKKGEAAKVMRYFPLIPRLKRLYMSTNTSQDMRWHKEDVHRLELRDDVLRHPADG
LAWKEFDKKYPDFAADPRSVRLGLASDGFNPYRLLNTTHSTWPVVLIPYNLPPWLCMKPT
SFILSTIIPGKLGPGLNIDVYLQQLIHELKMLWDGVDAFDVHSGKNFKMRAALHSTINDF
PAYAMLSGWSTKGFKACPTCTNFTPSYKFGGKICYVGTRKWLPLDHPYRREARLFDGTNE
YGVAPNRESGTEILRQQEQVEYVYGKSKKRGRRQADTWSIDLAKCRKKLKTDITGKMREH
FIIPNDGVYDKLALQRVDKYWRHYKYELKKTFFKPDRKTQEEHYDLVPSGHSRNDWIKLV
NYWFSEQGQKLSKFGKEARSLQCQLHIMGAGSYANLRADYEAEHGKSMGLIEASERSHMR
KDGSFVEGTATEDFLHDVKSKVDWLKLRGDSTCEEDLEEEAFQDVMNGGEIPERPQGFGF
GVKKRNVYGVPGLIRKQGYGKGKIKVVEDVNSNNSSPFNKSKEDLEKRNEELTMKYTENN
NLVKTVVTQFSDILDAMRNGKASSQLIDAAQFALVMATKQVGDSNAADATGGDGSRSETT
NVASKS
>Sgl09054 E3_adaptor/Cullin_RING/DCX/DWD 17.8 0.0
MRSKPITNPITAAIMLSIFLFFLIFFSGFFQNPSSASPSLRDPIANPTKPDPFTNLLGAF
RKWDSQMGCPKFREKFPTWGSSNGSNSLQVSGFDENGGIGCHKELKLKHVNILVKGWTWI
PDNLENLYNCKCGLSCFWTKSEVLADPPDALLFETATPPLQCNAVSFSRNCKLLASSSED
TTIALWELYPPRNTTGAV
>Sgl09104 E3_activity/RING/U-box 114.4 0.2
MRRHENSSKDRQTISQIIKIIKEISSSPECRNSSKRLYSNLVRRLKLLGPLFEELVDRQE
EDDDDVDDNDNEFVLSIDQVKGFDSLLNALISAQGLLKRVHESSKLFQAVQREKVSAEFL
HITGQIEEALSMISYDTLDLSEEVQEQIGLVHAQFLRAKARTESSDLQLEMDITKVQEEA
EPDAAVLQRLSHSLHLLTMDDLRKESRVFHEMVITSNSDLGDSFEKMSSLFKKLNDYLLT
LNPEIGMCDVDKGIIKHRSPVIPDDFRCAISLELMKDPVIVSTGQTYERSCIQKWLDAGH
KTCPKTQQTLLHTALTPNYVLKSLITLWCESNGVELPRLQGTSKTRRTGTSASSCDKAAI
GALLKKLAHGNIEEKRAATGEFRLLGKRNADNRVCIAEAGAIPLLVELLSSSDSRTQEHA
VTALLNLSINDTNKGIIVSAGAIRDIVEVLNNGSMEARENAAATLFSLSVVDENKVAIGA
AGAIRALIALLVEGTPRGKKDAATAIFNLLIYQGNKIRAVRAGLVDPLMRFLKEVDGGMV
DEALAILAILASHPEGKTAIGQAKPIPLLVELIRTGSPRNRENASAILWTLCMGDVSNLK
MAKELKAEPVLKDLCENGTDRAKRKASSLIELLQRVEEPTD
>Sgl09508 ULD/UDP/UBQ/UBQ_Other 32.7 0.1
MIKGELKKLLAQQTALEPEDQRLFFRGREKEDAETLLNAGLKDHSKLLLMERPASKEKKM
EEARKKEEISKACAAIAGVRAEVDKLSQRVFSSIPELCFFGRVVSCLLLEASVLSGTKVD
EKEFIIATELLMVQLLKLDSIEAEGEAKTQRKNEVSSFLFVNFKTCFVCYAHFC
>Sgl09595 E3_adaptor/Cullin_RING/DCX/DWD 30.9 0.2
MASGLCKGRFMNEVESLCGHTTPVESLAFDSAEVLVLGGASSGTVKLWDLEEAKSEFVYV
LHFIYPPFVRWVVSGGFDNVVKLQLQPSQVNYHSDLVSVRVTLSMSVILRETRLGKGKGN
AGGSSQKGGAEEEKYWDLSGLSLKGTLAPELGYLDNLKSLILHTNHLSGVIPAEFGRLTK
LEVLDLSDNNFTGVIPTDIAKIVSLKRLLLCGNNFEGIIPPEFEEYSSLSELQYDEYLAS
VTNMMN
>Sgl09699 E3_adaptor/Cullin_RING/DCX/DWD 16.2 0.1
MDNDNIHSLGESDEEDPPFDPQQEVDKGDPEDVAMHDLEGEKEVQLGACVRKLSIVVKWN
DVPQSLNNAFWDETVNLFHIEATVDKRNIFISAVAQRFRDFKANLVSGFITKKRKRSKKE
RDNKTPPDIWPNVSKDDWEAFVAQKTTPQAILRKEEQSNKQCKVEEETPCKLLLQDPKSA
EECLVIVANGHARPPREGFKVHGVPLPQGHYAVCVDHFQESRKLYQIPIPISSVDINTVE
EAHGTYVAWPFNLVLQKLAHKSNGLSKEKGKEHSIDNTIKLLGAGAFAFHPTLEWLFVGD
RRDTLLAWDVSTERPTMIGIIQVGSQLITSVAWLPALRLVATLSNDGALQVWKTWVVLNP
NRVPMAGGLVAHGGPRWLRRGSRWPTRDRQRQAVTTAAAGSGHGGYGGSGSGHGHGPRDD
EEEEEEEEEEEEEEEEEEERRRRRRRRRRRRRRRRRRRRRRRRRRRKRRRRRRRRRRRRR
RRRRRRRRRRRRRRRRKKKKKKKKKKKKKKKKKKKKKKKKKKKKRRRRRRRRRRRRKKKK
KKKKKKKKKKKKKKKKKKKKKKKKKEEEEEEEEEEEEEEKKKKKKKKKRRRRRRRRRRRR
RRRRRRRRRRRKKKKEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEKKKKKKK
KKKKKKKKKKKKEE
>Sgl09960 ULD/UDP/UBQ/UBQ_Other 33.5 0.3
MGAHTQQFCPSATSVDGQYLMIKGELKKLLAQQTALEPEDQRLFFRGREKEDAETLLNAG
LKDHSKLLLMERPASKEKKMEEARKKEEISKACATIAGVRAEVHKLSQRVFSSIHSELCF
FGRVVSCLLVSSLEASVLSGTKVDEKEFIIATELLMVQLMKLDSIEVEGEAKTQRKNEVS
LISQSLPTYNNVLCSSAQTGVEDGRHATSYAYACTDDSSVFEELRKEVVDQNLEETKPKV
VARFGKLLFHR
>Sgl10179 E3_activity/RING/RING 14 0.2
MDASQEALYEGCSTFSKLSFLLHLFHLKCLYHWSAKSFTKLLELLIDAFFQIKEFPSSYY
EAMKLLVNYWFSEQGQEAEHGKSMGLIEAWERSHMRKDGSFVEGTTTEDFLLRGDSTCEE
DLEEEAFHDVMNGGEIPERPKGFGFGVKKSDVYGVPGLIRKQGKEDLEKRNEELTMKYTE
NNNLLKTVVTQFSDILDAMRNGKALSQLIDAAQSALVMATKQVGDSNADATGGDGSRSET
TNVASKS
>Sgl10208 E3_activity/RING/U-box 107.8 0.3
MATKNETQLCVTIPAYFKCPISLELMKSPVSLSTGITYDRSSIQSWLDNGNTTCPATMQS
LSSPSFVPNLTLHRLIHLWSHSHSYTSSLSPSSPSLSSLLVANPKDITLPLKKIFDRVKK
SEANRRVLDESDEFLCSLVELMVKSDEVCDLELIFLILEVCDEQKIKKLMTMKLFDCLEK
FVFVLRNGSVESKIAVAKIVTKISTEKETKRLLIETKDLISEMFKLVESHFDHLIEAGLA
ALISVASTKSVKIELVKLGMVRRLREIIVERFNEKTIQCSMEMMEVMATCTEGRAAICKD
EDCVAEVVKRLMKVSEKVTEHGVTVLWSVCCYFRDEKVKEIVGRSNGLGKCLLLLQSNCK
PIVKQMCRELVKVLRSDYSKSCLGGYNTKTIHIMPY
>Sgl10255 E3_adaptor/Cullin_RING/DCX/DWD 28.7 1.0
MASGLCKGRFMNEVESLCGHTTPVESLAFDSAEVLVLGGASSGTVKLWDLEEAKSEFVYV
LHFIYPPFVRWVVSGGFDNVVKLQLQPSQVNYHSDLVSVRVTVSMSVILRETRLGKGKGN
AGGSSQKGGAEEEKYWKACHCDAEMRMEYKVLVLGSACCSSAATTCSSADEVSFASSGFM
FVYGLLQGPDDELFPAQEVLLHIQTRIVDLVPDKDNIVTIRLLVASSDIKCLDEGDGSLA
KLKKLTGADAEVLPKEKVPAFVSGSDELVQLGLMQSNAAESPAELYWKSKFGNIQMPKVL
KDSLELGSKDGIANINPQFRVHSDGEDKTFFYLYTRHPNVNASQLILHGRVIFFTQEKLL
TVGTTMKLHFKKIDNGAKFLPLHLAKSMAVKSNNLQSILNVLSINPKSSVAQYIEKMTGV
CEQTTSIRDEIRYCATSLEDMVDFILLNLNSKNKKLMVVSTKVDGDIVMKYTIQNAHKIG
NNDNQTMVCHKLGNPYAVFLCHNVKSTDVYGVSLVDAKGKQAKAVAVCHNDTSSWDPKYL
AFKLLKTIPGSKPICHFVSGDTIVWVGN
>Sgl10278 E3_activity/RING/RING 31.1 6.1
MATDPKVHIPCDHGSDNNLPSSSFSNRVNIRFKYDIFEQCTFHLSNGIKIAMPFCTYKHD
QETAPLSLNPYCHRCMDTLTEFFVPLGYTKDESTCVLDFIRGNFESRHTITSDLDLLYCA
DLYVRLQYDCSSNTDSFLEWAIRTSDEIFIEKVPTPTSFEAIDAMERLTASTPDLGATTT
TCAICLEEILKNNDEVGRRLPCMHDFHETCILEWLLKNHSCPLCRFELPPNMDSFIIMKY
K
>Sgl10400 ULD/UDP/UBQ/UBQ_Other 24.7 0.0
MVEFLEGHAVSLSSINTIHLKSHSSLISVSHSNSLPLASALNPAGVSPFRRHHLQEKRKK
IKMIEVVLNDRLGKKVRVKCNEDDTIGDLKKLVAAQTGTRHEKIRIQKWYNVYKEIHDGM
GLELYYN
>Sgl10429 E3_activity/RING/RING 26.8 5.4
MMAVSIDCPHDDDSYANNIDQRLVVRITTRSYQHIVYEDQNNSTHLVSREPQPCSRLNTY
TRSWNSLCPQCKQEFIEFLEQRGFDSDEAYEEYTCLDSVVQEKLHDYYFHDQRNHRRYNE
VVYHEVRLYAPHRVCSEEEYRALVGEGVVFESIVVDSPVPASESAIQGLELVSDVQESIK
EHNVCAICLDGLVSEEVEQESEDNKSKKLRDTVIVRLPCKHLYHRGCVVEWLGWNHICPC
CRFPLPIDYDQVSI
>Sgl10493 E3_activity/RING/RING 9.8 10.1
MWIGVCLSPLRSSLLIFVISVSFFQSTFSLSLSISSSSRFTLRSGLFMAKVSRVRRLKYR
CRNGKAERVSSCSHKIFKDIKKPSRLSEKKDWEDATCSVCMESPHNAVLLLCSSYHKGCR
PYMCATGHRFSNCLEQYKKAYSKGIPGEITPSLNHGWSEERMDEMSELLCPLCRGQVKGW
TLVEPARKHLNKKQRTCMEDNCSFVGNYKQLKKHVKTEHPWARPREVDPSLEEKWKSFER
ERELSDVMSTLPPGTIVFGDYVIDPNFNPFIRDYDLEVDDLLDDDDDLEPTVFGANRIRS
GGFQLHRTSGRNYDSFDDDDDDDVGIHRHSAFSRGDDRAPVSRNNRRMFILERSHRRRRR
E
>Sgl10513 E3_activity/RING/RING 28 8.6
MGRFLLTTHLTSSSSSFTTATTTTNDTTDLPCTDFCDPSCGDFDACYAFPAIPDDTLPPP
PPLLPPPPPTTTVATPSSSNFIHDLFNLSPIAIVIIIVLASAILLISYYAVVIKYCSLLT
RLITRRDLARMQPNQSSDPNNPRTTAANNQFVDHPIWLISTVGLPQSMINGITVIRYKED
GLIDCTDCSVCLSEFQQGETLRHLSKCRHAFHIECIDTWLRSHTTCPMCRASITVPNPNS
PTSGHSGRGELTQVVDSDSNDLELGNTQHGISTSNHNNNNNNNSNDSVTLLVGEDRGTQT
GEYVAATNILEILLRRSNSVDYQNSGMQPNVSSSNSSASSSSRPLHQRMSLKRSYSWSEK
VFCQNDRNSVMSP
>Sgl10516 E3_activity/RING/RING 47.3 24.5
MPWTFPSPTNVTLLGFLLLLLFAPLVTAQQPPPWPESNKNYNSPMATALIVMIIVFFSVG
FISVYLRHFIACLGFDAYGGLRRGGGGARARDPPNRGLDPTILNTFPTFLYSDVKIHRVG
KITPLECAVCISEFADNEILRLLPKCNHVFHPHCVDLWLASNVTCPVCRANLEIQPYNNN
SGTSDDDGESVGRRRPQAAASDNNNNDQVIIRVEETTTTTIPGTEGMVKSPTQELLHRLN
LSESGRIIRLPRSHSTGHSLVGDSDRFTLRLPEEVRNKLIINDNNYNYNYNYNAIVSPRV
GYRPTNMGCTDPPNKPDRWRFSMSPPFISRPNSPKLESPTPNNSNSNSNNTPGRLLRSPK
SLFRSLKSPNKSPLHRVVSCNDIGERSSNRLWDNRTPQDLDLEDQDQHIYHLSTCFLLIL
ITSISLYPSFTTAESSSSSSNDSYNGSPLPTTAIIIVAVVFVVGIATCYIRHLIVCFRGY
IFGTQSGGDGAGLRRRDAPRGLDPSVIATFPTISFSDVKLYLTAKTTPLECAICIFEFVD
QDLMRLLPTCSHVFHPHCIAPWFSSHSTCPVCRANLEILPDTQMTTSPESLAHVIQHQRS
VDVDQSEPSNQEQIVRPHDHDHHHSDVILQIRETSDHNKISSGEHKSNSNGVGERSRKFQ
RSHSTGHSLVENCERFTLRLPEEVRNKLVNVKDNNLNGLSNNPLVSPRCGYRAWSVTTTN
ATMSVKPDQQWRFTMSPPFISKSGSSPDIAGSSNNTSSSNNNNGTNNIVGMMRTPKSFFK
SMKSPSKSQLNRVVRCDDHDIGERSSDKLWPNRTSQELGLEHHQ
>Sgl10517 E3_activity/RING/RING 29.3 8.3
MGRIRNKHFLLLLHILLLLSTALAQADGKGKKSGKWWSTPLIMVVYIVFFLVAAGLAFCI
RHYRDRRSLMEHPRYQRRAAEGGLEAEEIESLPSLRYSEIKMNQIVKGKEQLECSVCLAD
FKDQEVVRILPDCLHVFHPHCIAPWLATHVTCPICRSSLEHRQGSSLSMSSIFDDGTSGH
PSQRFDYSGDQVYEANGDDHVITVDIEESSPTSHSSQLNVGAVVTNSRMKLQRSYSTGDL
TAHMIDRYSTTTRSSSISSLLMPKEITPKNEHRKIFNKENSWSCFSPKSDSFVDYS
>Sgl10518 E3_activity/RING/RING 32.3 7.2
MSLKMQNKSLIIILSYVVFLLQLSPAHVAAQESFKGNLGEPFAPSTIIIVIIAVIFLFTG
CLAVVLRRFSDGCFGLHVIPIDHPDFTSDGQLTTKGLEADVIKSLPTYFYADVKQHRKAE
VELECAVCLNEFQDPETLRLLPGCSHVFHPRCIDPWLAAHVTCPVCRQSLLEPPLTGKTT
NTPHSIIDIVPTTTQVDQSNGPAHAGAQNDNHDDEDDMVHDGVKKMIVGKFPRSHSTGHS
IKRHTLVLPEDVLVQNNLVNRTKSGLRLSGMISPRSGYKCGWFSMTPPITTINPRTKSLL
SSGLIKSSSSKNLTTIPHVKTTSDRCWNNV
>Sgl10548 E3_adaptor/Cullin_RING/DCX/DWD 81 10.7
MDSFPFHDANISSLIDSRTIDFRHDVKHSLHLHSSMIRRLSLERELKGHLGCVNTIAWNS
TGSLLVSGSDDTQIKIWRYSDRKLLNEINTGHSSNIFCTKFMPETSDEIVASGAGDAEVR
LFNISCLNEGSIDLTPFAHFHCHTRRVKKLAVEVGNPNVIWSASEDGTLRQHDLREGCSC
PPAGSSNQECRSVLLDLRGAAKRSLVEPPKQPLQLKSCDISVTRPHLLLVGGSDAFARLY
DRRMLPPLSSCQRKNSPPACVNYFCPMHLSERGRSSLHLTHVTFSPNGEEILISYSGEHV
YLMDLNQDCGKARQYTSGDVAQLSTFSPIPTEVEFTPLGAVASEKISSDKSYATVQHGKC
KKLLEIAKTCMEEGTEYYYGIEACNEVLDGGYTIDASLKLDCLCARAALLLKRKWKNDAH
MAARDLNQARKINSSSFKAHFCMSEALCQLGKHKEALDFALAAQCLDPSNTEVAEKVEYI
QKQLSAAEAEKNKKSNDVGSKSEPRAGRVISLSDILYRSEPNSDVSQDGPRSEREDSDFD
EELELDFETSMSGDEDHDAESNVLHGSVNLRIHRRADSTREAGGSNGSCGSPSSSYQNDY
SCYQPEAVIDMKQRYIGHCNVGTDIKQASFLGQNGDYIASGSDDGRWFIWEKKTGRLVKM
LLGDEAVVNCVQCHPFDSVVATSGIDNTIKIWTPCAPVASMVASGSAGPVADNVLEVIEG
NQRRLRQTREAILPYELLERASFHPLFSRIVWLLYIYLICLLAGQSNPSLKNFVKYSSCV
ATELAMTKLLEFQVSCLCNEGQQSSSVFNFYLVMHFALFNDCFFHLTGDLESAYRWMAAK
MQPM
>Sgl10579 DUB/USP 247.9 0.0
MLVPGDLGFRVAVFFIFLVFPVFAFVLRRKWRIAVARQQEINRLLVLASEEAARAEVEAT
FGYSSSVSLPSTHRLCAVCFTPTPNRCARCKSVNYCSGKCQIIHWRQGHKDECHPSVYHS
DSCDEEVSFVEDADKKFCSDGDISVSENGGFQHDEQAITSQEKTGFTASAYCPPELSVKD
VQNEVCHPSLADDPVSHGIAGASQLHPSSSSDGICIDDSGSEIDSIHDLNSDPYDSCSPM
FDNLETDSSDNNLEQPKPLVENSHPRVASNGNISGLSELKEEASGSITGSSGFSISRSDK
NLTKPLVATPGFWDGSLDYCRSKKTVQCTDVKPEIGNIGDPSSGMLSQGPEASPDVYPGT
FSAVKLVAEPASAKKDPKDPTQVKSSMDLGSREVVTSVKVTSSDKELKSGEVGAADEKLE
GGALPACISEKTNDQIRNTKDALHSRGSKKAGLSPKALNGSPSGLKEPTASTRKSVKASA
DASMPVHVARSAPNAAVGLKTSMLKVVEQLRAPKPMKQGDGVVRNREKPVFSYETFVKLY
HWSKVELRPFGLINCGNSCYANVILQCLAFTPPLTAYLLQGLHSKSCAKKEWCFTCEFER
LVLKGKEGGSSLSPIGILSQIQKIGSHLSNGREEDAHEFVRYAIDTMQSICLQEAGVNAS
GSLHEETTLMGLTFGGYLRSKIKCTRCRGKSEKQERMMDLTVEIGGDIETLEDALRQFTG
TEPLDGENKYHCGRCKSYEKAKKKLNILEAPNILTIALKRFQSGKFGKLNKAIRFPEIFN
LAPYMRGGSDKSPIYQLYGVVVHLDVMNAAFSGHYICYVRNVQNKWYKIDDSKVKAVEIE
RVLNKGAYMLFYSRISPRAPKSIRSALVSRDLPIKSKMPAADASRVNVRSTTSRQRDPFV
DANHNFDNLASLGYIHQSGTHPLPVRNFHDFDSSSDNSSLFSQSDEVSSSTTDSNRESIS
ADDFSEFIFGHNAFFPHSSDSDTSSSSSSSSPQYTRHSPLSNPERYASASPDSNARSDPS
EDPSCSKAPLSRVEESGSVGGVSFLHSNSSSKQGRKVVNISSREADAEKLGRTNPLENGK
PDVYQRQSGRKKSD
>Sgl10589 DUB/ULP 147.3 0.7
MKTRDTSVYDFKEEDELTDNCYPWSKLTNPKFGDDVALTKYQFLQHASTGSITQTKEFHS
LEKIHVVTIDDDDRVFGNDISTAAQDSTDEAASKQSEVSGAISDRINGSAEAEAGLLDDC
DSIQTNSPSTSGSEQEENYVPIYGQAHDQSISGWTMEETDAIYTDYVSYGDKYFPACFIY
FSKSSLKIVTSVSEEEADKSSFEWSVNDLHSIESQWSNKVSTAKVTVRILPKDAVPAENA
HSMTGIEMFEFLVHDPYWLDRQEAIMALDVRYKAVWSIGLNGRNCEGGPFPLESDDSSLD
PYIPIFQEPFEEVVYPKGEADAVSISKRDVDLLEPDTFLNDTIIDFYMMYLKNAIATTDR
HRFHFFNSFFFRKLADPDKNSSGVFDGKAAFQRVRKWTRKVNIFDKDFIFIPVNYNLHWS
LIVICHPGEVATFKDENVDDSVKVPCVLHMDSIRGSHAGLKDLVQSYLLEEWKEKQKETS
EDIASKFLNLRFLSLELPQQENCSDCGLFLLHYAELFIAEAPENFSPFQINEFDSFLKPD
WFMPAEASLKRVHIQRLIYELLEGPLSENASLRNNETQPSAFPESKEIDNGIKIISARRS
PRKTWNPLHSHPVQGMELGLLDMSLYRTSDCTNVSGLGMRDLLEQYQQYDQEASLGRPGS
LMPQIKEEVEAADHLASSSLGQIKLQTMDGVTPEACDMGYTPTEIHGGFHWDSGLPYQGD
LDKSLLPSSNSSDDDDDDPEDMVIIECEQDVEGATSGENKILDQPKENVDNFTESYESAS
SDMMETPAEDSQELAKIYGSNDLEDSPFCSRKEAKEESPQEEAEEASLKEEAMEASHQEE
AVESSHQEKAMESSHQEEAKEASHQEEAKEASHQEEAEKASQQEKAEEAFQQEEAEKAPH
QDFEKFDEVGNAAGIDVIVEDSSTDTDEEHSAKRRRLTAPGDGEIELVTSLSKEVQV
>Sgl10616 E3_adaptor/Cullin_RING/SCF/F-box 21.7 0.0
MASDLNSTIVAELEAAYRWRTAQYFVTQRPWLDLYGVRVSPVAAFGSVSNKPSLDPALIH
RALPDELLHEIFVRMSPYHLGVACCVCRKWRYTIRNPVFWRNACLKAWQLSGVVDNFKLL
HSKYEGSWRKMWHLRPRVRTDGIYVSRNTYIRAGIAEWKVTNPVHLVCYYRYIKFYPSGR
FLYKNSSEKLKDVAKFMNIRASKTDRIFRGQYTLSDDKVEAAILYPGMRPTVLRIRLRLR
GTTAGANNRMDLVSLVTSGVNDNEANHEEDMLDLVEGWQDDETHNPDVPAVSHKRGLTPF
IFVPIEEVETSILNLPVEKMDYFVPD
>Sgl10618 E3_adaptor/Cullin_RING/BCR/BTB 59.7 0.1
MYESVMGLSAQLQSDREREKMGGDTKVDTISRLAQWKIDNFGPCSYKKSDSFKLGLWNWH
LAIEKNRYLYIRLFPEPSRVSKDQPPIARFILRVSNAGVSRRPYVSPIHERMLRNSDDFV
WPVDTTFYGRFIIDVEFLDLKIGALSGGQPVSIWPAEGNMQSLSTQSALQTMSRMLYEGI
LSDVTINTSDGSMRAHKAVLSASSPVFQSMFLHDLKEKESSTIEIDDMSSESCMAFLSYV
YGTIKPIEFWKHRLALLAAANKYNMSDLKQACEESLLEDINSGNVLERLQEAWLYQLDKL
KKGCLTYLFEFGKIYDVKDHISSFFLTADRDLVAEMFQEVLTVWKPV
>Sgl10659 E3_adaptor/Cullin_RING/DCX/DWD 36.9 8.3
MNIVKGVANLIRGSSGSHHSGSSQGLQAERFALPAQNVQFSEVGNESILKDLWVKFEKAV
DKVEKRKMFYVFLKQFVDMHNKWEPIIAGESSDSTLSAVSHAEHSLPSGSKVVGCFAGHP
TEVIVALIDEITQLTCIVTELDAGFVKSTSDPLIVSTSLKISSEGITALEALMIVVRSVH
NCRVLGYNGGIQKLVALIKAAVVQLKAIAGAVAGEETLSDVVLDTLELLQKLLVHVVSIL
CSFIDLNSDAYEMANIYSNITFSLSSGGASLIDPSNTFKVRHGKMHPWKQTAIMSVMEAG
GLNWLVELLRVMRRLSIKEQWTNLSLWYLTLRALHSALSENSRAQNHFRSIGGLEVLLDG
LGLPSNSALASQKANTLGRQRFENILLALFQLHVLSLEVLREAVYGNLNNLQFLCENGRV
HKFANSFCSPAFALQDFQNRSKEFPVEGSLENLALTSKYGSDEKMRTKESAVIPITGEFI
KYWRTYALTLSQSFCSFILSLEDAKSDSTDGSTSRQNMPISSLFSELSIRWILRVLLIVF
PCIEACSNEDELPTYLRMFVCILQLQVLHALRQVLRSSPKLLEVFRAEKLWELVFSEHFF
FGATLKDSEVNCSATKLSFLSSSGNDNNMEVPAEKNLRIEVVSFAELAATLKETTHNLSE
CSALLDALEHSALDPEMANVLCNSLLRTLEHAREKTLASFKELNAMSRVLKVACIQAEEF
RSTDASCNEALTSVEDIVPEDFHNSDCSATSHHLNRSIAASVELFKAYFCAADDAKSLVL
HNEECINCLFNLFWDRDLRNLMLGYILDLMKAAPTSKDDQTANLLLCSRYLETFTQVKEK
EKDFGEVSIELLSGMRVMLQMDQELFRCLFPLTLDVYYLSYLDTMSVLITHIARNGCFQY
FQDLFRNGECFIHVVSLLTGVIDTKNAEKLVLDVLHTLISLLSNNDVSKAAFRDLVGKGY
QTLQSLLLDYCHRQASECLLNALLDMLVDGKFDAKGSPSIKNEDAIILYLCLLKESSISV
QQEGLNIFLQLLRDSISNRASCVSAGMLSFLLDWFSEEDNDSVILRIAQLIQVIGGHSIS
GRDIRKIFMLLRSEKVGKRQQYCSLLMNCILAMLNEKGPTAFFDFIGDDSGVILKTPLQW
PLNRGFTFSCWLRAENFPRCGTMGLFAFLTENGKGCFSLIAKDKLIYESVNQKRHCISLQ
VNLAKKKWHHLCITHSIGRAFSGGSLVKCYLDGHIVTSERCRYSKVNDPLTKCSIGAKIL
LPFSEEENLVYSIKDISPFLGQIGPVYLFNDALTPEQVMGICSLGPSYMYSFLDNEYVLS
SDNPLPGGIFDAKDGLAAKMIFGLNAQASTKRALFNVAPLMEHAIEKNIFEATILPGTQL
CSRRLLQQIIYCVGGISVFFPLFTQSHWYENEEQSDSRNPLLMPISKERLTAEVIELIAS
VIDENVENQQQMHLVSGISILGFLLQSVPPEQLNLETLSALKHLFNVISNCGLSELLIKD
AISTIFLNPLVWVFTAYKVQRELYMFLIQQFDNDPRLLKSLCRLPRVLDIVRQFYWDNAK
CRSSGAGRPYLHPLTKKAVGERPSKEEIHKIRLLLLSLGEMSLRQNIDDSDIKALIAFFE
ISQDMACVEDVLHMVIRAISQKSLMASFVEQVNYIGGCHVFINLLQRGHEPIRLLSLQFI
GRLLVGIPSEKKGLKIFNLAVGRSKSLSETNRRTHSRIQPIFNAISERLFSFPLTEHLCA
TLFDVLLGGASPKQVLQKQTLPERQKSKGNSSQFFVPQVLVLIFKYLSDCKEVSARVKII
SDLLDLLDSSPSNIEALMEYGWTAWLTASMELDVVKHYKLESVGQTEDEIIEQNSVRTLF
CVVLCYFLSSVKGGWQHLEETVNFILMHFEKAGVSYHYLLRDIYEDLLQKMIEFSHEENV
LASQPCRDNVLYFMRLIDELLLSEIDHKLPFPATTSEFSPDLLEVEGFNDLGTALYDALQ
GESVERMSRNPQATNQLTHNEDVIADENWWTLYDCLWVVVSEMNGKGPSKTLPKSSSFAG
PSLGQRARGLVESLNIPAAEMAAVVVSGGLGNALGGRSSKNVDKAMLLRGEKCPRVVFRL
VVLYLCRASLQRASRSVQQVIPLLPSLLLSDDEQSRNRLQLFIWSLLTVRYQYGMLDDGN
RYHVISHLIRETVSCGKSLLATSIVNGNDSSDPGSAPADIGAVHNLIQKDRVLIAASDEA
KFIEASKADRMRQLVDLQTRIDENILTDSGQKKAFENELQSSLTETLASDDSRRAAFQLA
CDEEQQVVAEKWMHVFRSLIDERGPWSANPFPNCAARHWKLDKTEDTWRRRPKLRQNYHF
DEKLCYPSSGASENEVTAVPCENKSGAGIPIPEQMKRFLLKGIHRITEEIDPEASESEEE
SSDSKGMNSEEVPDGQSSELLKDGDQMDAVHERKESSSPAFETDNGQVLVTVPCIMITPK
RKLAGQLAVLKNVLHFFGEFLVEGTAGSSVFRTFDSLKNSESEKVDQLNEVEKVKFLKLP
VDTSLFSEKHNAIGTLEKQLKSIKRHRRWEVSKIKAVHWTRYLLQYTAIEIFFSNSVAPV
FFNFASQKIAKDVGSLIVTSRNDLLFPKGSAKDKTGAISFVDRRLAQEMAEIARESWRRR
EITNFEYLMILNTLAGRSYNDLTQYPVFPWVLADYSSETLDYNKSSTFRDLSKPVGALDP
KRFEAFEDRYQSFTDPDIPSFYYGSHYSSMGIVLYYLIRLEPFTALHRNLQGGKFDHADR
LFQSIEGTFRNCLSNTSDVKELIPEFFYMPEFLVNSNSYHLGVKQDGEPLGDVCLPPWAK
GSPEEFIYRNREALESEFVSSNLHLWIDLMFGYKQRGKPAVEAANIFYYLTYEGAVDLES
MEDELQRSAIEDQIANFGQTPIQIFRKQHPRRGPPIPITQPLRFAPGSISLTSLVSSFSY
TPSALLYVNVFDSNVILVNQSLTMSVKLWLTTQLQSGGNFTFSGAQDPFFEIGSDVLSPR
KIGSALAETVELGSQCFATLQMPSENFLISCGNWDNSFQVVSLSDGRVVQSIRRHKDVVS
SVAVSSEGSILATGSYDTTVMVWEVCRSRALEKRVRNSQSEIVRKDYVISETPFHILCGH
DDIITCLHVSMELDIVISGSKDGTCVFHTLREGRYVRSLRHPSGCALTKLAVSQHGRFVL
YSDDDLTLHLYSINGKHIASSESFGRLSCVELSACGDFLVCAGDQGQIVLRSMNSLEVVK
KYHGIGKVITSLTVTPEECFLAGTKEGNLLVYSIENPQLRKTSLARNTKYKPSIVG
>Sgl10712 E3_activity/RING/RING 34.5 5.3
MGFGVSIKKLFFGLCLILIFSLSSASVVLEGKNITYVFEDIEANFAPPLDSSGVCGKLYI
AEPLDACSSLKKAVDDSRICNSPFALIVRGGCSFEDKVRRAQIAGFHAAIIYDNEDGGAL
VAMAGNSVGIKIPAVFVSRATGRKLKNYVKPGMKVWLFASYESSAWSIMAISFISLLAMS
AVLATCFFVRRHHVRRERPHVRVREFHGMSSRLVKAMPSLIFTAVTEENCTASTCAICLE
DYIVGDRLRVLPCKHKFHTVCVDAWLTAWRTFCPVCKRDARTSNGVPPASESTPLLSSNP
SSVASTPFSSFRSSSVRSSAIQIASPSHQSRPSSQNPSVASSPQIPRPLHSHQNQPSPYM
SMSRSSLDLRNMSSQRSYTSQYMSPGSVGYPSVSPLNTRYMSPYIPSPGNASSSYLRSSS
MRYPNPLHYSESAASFSPYNSAQSLPGC
>Sgl10764 E3_activity/RING/RING 15 17.6
MEVDEPPTNDYCSICHGEFNIPCQANCSHWFCGRCILQLWDHGSALQPCRCPLCRRPINL
LIPTDTYRRQRDNPEISSILSRLEVYNRQFGERSNDLVQRLRDLPFLLRRLSRDMLDPQR
SLPIVIKTRVYLAVILSAIYLVSPVDIIPEGILGVFGLLDDLILLLICLLYVAAIYRSVL
VSRHGG
>Sgl10781 E3_adaptor/Cullin_RING/SCF/F-box 20.7 0.0
MTTKRKCLIEERYNEMKKKHMIFIKMVEERAAKMQTSWVSFLPNDVMFKIFLLLPVKSLL
SFTSVCKAWYKLIYSAEFVEAYNAQAQTTPIVFRLKGVEEQRLNTYHVETQIKQSENFNF
FPCGSKKRRSKFIHYLEMENGNCKVIDLNISLSGAVLATCNGLILINSVNKLLGTHVCFP
REKPLVHSQENLGRLIVMNPMTRKLIGFPPGTLPSELHRESYGLAFSQTKGVYKVVHLFM
DSSAHIACEVLSLQTRLWKAVDGPSRLLFNNFGQPPISTAGALHWLPGSPSNDYIISMGA
DDEQFSSTDLPTSMGKYDRLVEMGGFLSFVKTLDKCIIEVWLLKALEGSEWVKQYTICCI
DFVYMLEYMVDDYGAQSEHYFVPAFALNAKEMVFRRGNQLYSYNFELEQFREFNMDHGKL
KGYDSIMPHSNNLATWETLESLS
>Sgl10812 E3_adaptor/Cullin_RING/DCX/DWD 19.8 0.8
MTKNITSSNSPISDELDLDSFLRRHNATFSDEDEEEDDQKPQISDTLHRTIDDILNDSSS
DSDHDVVSVSSSTPYSKTLISGEKVVNSTQTKFNLIQRLKSDEFASRKPPIGSQNSRNSS
IFGSGVSRKPGAALAAAAAASRNVRTPRSAVMMSRRALSESLEGKVSDDELLGFVKDDVK
FEGDNLNEVVGEVVCERENDEKDEVMMDSFDKCGVRGCEGSNIKEGIEVKQKGDDVEVNG
RGDEKGGGELENGEDFGRKMEAVASDEKVEILDVERVDSGGFAEEEAGCMLDVEEKGMGE
GRDVDENFVEGFGLSLEVKNEEEEEDSGFVPRQVQEAGMSDESGTGRDELNFTSDDDEER
IAQLEDEMDSESAEDTLRSVKKPLELAEELEIKQASTGQDWEEGAAAQPMRLEGVRRGST
VLGYFDLNAENILSRAIKSQAFIRDYGTPQVIAVHQNYIALGMSKGVVVVVPSKYSAQHP
DDMDPKMLLLVAQADRSQVPVTSICFNQQGDLLLAGYGDGHITLWNLPRGTVAKVITAEH
KAPVVHTLFLGQDSQATRQFKAVTGDSKGLVLLHEFSSGLLVGVTVKTQCLLDGQRTGTV
LCASPLLPDDFTCPGNTTGSSSSSSSSIGSVMGGASPWKFFNEGSPLSEEGVVIFVTHQT
ALVVRLTPNLEVYTQLSKPEGVREGSMPYTAWKCTTQPRASSSENVNPEALERISLLAIA
WDRKVQVTKLVKSEIKESEKVEPKESGKWTLKVCGSWTLESAAVGLAWLDDQLLVVLTLA
GQLCLFTKDGTLIHQTSYATNETGEDEFMSCHTYFTNVFGNPEKAYHNSLAVRGASVYIL
APRHVVVSRLLLWRERIEVLRNAGDWMGAFNMAITLYDGQAHGVVDLPRDLHTVQEAIMP
YLVELLFSYVDEVFSYISVACFNQTGKVEEVDDSLNKSISASSEIKEQFTRVGGVAVEFC
VHIKRTDILFNDIYSKFVAVLHRDTFLELLEPYILKDMLGSLPPEIMQALVEHYNDKGWL
QRVEQCILHMDISSLDFNQVVRLCRENGLYGALMYLFNKGLDDFKTPLEELLSVLRNHER
DATVGYRMLVYLKYCFSGLAFPPGHGKLPLERLPSLRMELLLFLLQDSGGPKSQTGASLT
STGAYLNLHYLLELDTKATLDVLRIAFVEDERFKLDQSLHDASDTNVDNLKNNDSVAGDQ
DLLVQKIVDALVIVLDIDISQSVRSTGSDDTGMVIWPTKKDIGQLIEFIASYVASKRANV
SKSVLSQIIEYLTLENHLEVNDCVQMSESKKKREKKVLALLDVVPQTEWNASYVLHLCEK
AQFHQVCGLIHTIRNNFFAALESYMKDAEEPVLAFSFIDGILLQLSESEYVAFQSVVTSR
ISELVTLSRECTLCLVSYHLNKEREHVLSKLRSTPRSLFLYLKTLFEVYFSGNLDFSSIR
VDNALDGPWGRKNVTKNSLDAYMKRIAEFPKFIRNNPIEVTDDIIELYLELLCQYEPDSA
LKFLGTCENYRVDRCLLLCQKYGIIDAAAFLLERVGDVGTALSLILSGLNDKFVMLDMAV
GSKISDMDVGKHASMENFAAASELKEAADIKKILHACIGICQRNSPRLDPEESESLWFHL
LDSFCKLYLYLQSTLKIIYQLSLQAMKVTQKSMPSHGGFIRLRKVLPF
>Sgl10813 E3_activity/RING/RING 12.2 10.4
MIGYVRLPSIMAKLLSDNGSQEFGDFKLTILGMLGTYSFELKILDTAKCLIEDDTFYTMS
LLKKGASKGYAPRSLQCCICNCTFKTSSSSGIRLFNCGHASHLQCDVQENTSTQSFSGGC
PICVQKKKIHKAKGKMVEQGLVGASPSSSQRAQGTSILHPHEFDAFENSTTPQISRFEIL
SSLQKNQRLIPTDTMPQLRLAPPAVYHEKVNKRTHFPSGASREGQVDAEKPSRNKQLRDV
KVKGSQIRFPLKSKIFGKEKTRVI
>Sgl10871 E3_adaptor/Cullin_RING/DCX/DWD 21.3 0.8
MGSLSEEDDRYFDSKDYITPVDSGSDGVENSDSESRCVEDVVRNFGYDVWIRSPGTIGER
RQKLLKLMGIGSNQGVEESEYADSSSSFEGEVVDNARILENSGTVLRSSFKDLCSSSHSS
VSWCSNDTQELLDIALEENLVRRIKNLDDGSEFIVDELGQDGLFRRLREVGSNRTLSGEE
FEKILGLSPLVQRAMRRDVGWAQKNVAEGKRRTKKGWLRKLGVVACVADTQSGINRVDSL
PIQRRRAHNVRVRTCRKRSKEFSGLYMGQDIVGHEGAILTMKFSPDGQLLASAGEDGIVR
IWQVIESEKSEIVHVPDVTGSHVYFTVNQFGELVPLNVGKEKRGKLKSLRKSTESACVIF
PQKVFQLEEKPLHEFHGHHGEVLDLSWSLYLPCILHLYQYTTSTI
>Sgl10872 E3_adaptor/Cullin_RING/DCX/DWD 92 13.1
MRRDVGWAQKNVAEGKRRTKKGWLRKLGVVACVADTQSGINRGQDIVGHEGAILTMKFSP
DGQLLASAGEDGIVRIWQVIEPEKSEIVHVPDVTGSHVYFTVNQFGELVPLNVGKEKRGK
LKSLRKSTESACVIFPQKVFQLEEKPLHEFHGHHGEVLDLSWSNNKCLLSSSVDRTVRLW
KVGFDDCLKVFSHNDFVTCIQFNPIDENYFISGSVDGKVRLWSIPGFRVVDWTDLREIVT
AVCYQPNGKGAVAGSISGDCYFFDTSENRLQLTNQTSIHSKKKAPLRRITGFEFSPGDPN
KLMVTTADSQVRILKGIEVICKYKGLRNAGSQISASFTSDGKHIVSASEDSFVYVWDCTN
SDRAISSHFRSKSSCERFFSNNASVAVPWHGTTCGNVLPSLSGSSTNYSGIMVRYTTESG
FEHHRTSTDSPQLRTSLFSTDAISLGFSDPFSRGIATWPEEKLTNSNSLTVSSDTSKSEY
KFLKTTCQNMAGSTHAWGLVIVSAGWDGRIRVFQNYGLPVRL
>Sgl10874 E3_adaptor/Cullin_RING/Cullin 494.7 5.8
MADRKPPIELEEGWSFMEKGIKKLKNILEGLDEPPFNSEQHITLYTTIYDMCTQKAPHDY
SQQLYDNYKQAFVDYIMSTILPALMEKHDEYMLIELVKRWSNHKVMVRWLSRFFHYLDRY
FITRRSLPSLNDVGVHCFRDLVYQEIHGKVKDAVLALIHVEREGGHIDRALLKNVLGIYV
EIGMGLMDQYEKDFEQHMLDDTAAYYSRKASSWIVEDSCPEYMLKSEECLRKEKERVAHY
LHASSEEKLLEKVQNELLLVFENQLLEKENSGCRVLLKDDKVDDLTRMFRLYSKVPHGLE
PIGSIFKQHMTEEGTALVQQAEDAAISKAENAGGGSHEQVFVRKVIELHDKFMVYVIDCF
SSHTIFHKALKEAFEVFLNKGVAGSSSAELLATFCDNILKKGGSEKLSDEAIEDSLEKVV
KLLAYVSDKDMFAEFYRKKLSRRLLFDKSANDDHERSILTKLKQQCGAQFTSKMEGMVTD
LTLGRENQTHFEEYLGQNPNANPGLDLTVTVLTTGFWPSYKSSDLNLPSEMVRCVEVFKE
FYQTKTKHRKLSWVYSLGTCNINGKFGPKTIELIVGTYQAAALLLFNTADSLSYTEIAGQ
LNLADEDLMRVLQSLSCAKYKILLKEPSTRTISQTDHFSFNSGFTDRMRRIRIPLPPMDE
RKKIVEDVDKDRRYAIDASIVRIMKSRKVLGYQQLITECVEQLSRMFKPDFKAIKKRIED
LITRDYIERDKENPQLFKYLA
>Sgl10879 E3_adaptor/Cullin_RING/DCX/DWD 46.9 23.6
MATPSSSSSSSSSVDLTDHLPLQLLKSETIPPSPNHSNSIDWLPDFAGYSWVAYGASSLL
VISHFPSPLSPHQSHIGPIFRQVFQLLPSYDVVSVVWSPVMPSSGDLAVASHNRIFLYHY
DSSPGSFCWSQTTLLVQSIEVEVITWTGSGDGIISGGSEVILWKRSGKSWEIAWKFRTKV
PQTLVSTTWSLEGPSASGACANKINAKELATVPCNSNDHVSVFQYDGKCGYVATELRHPQ
PVLAMQWRPCGERQLNRDVLYAPRNVLLTSCLDGVVRLWGEIDGSKMRKGNKDNREMSTS
RRSFCVVAVIEINQSFGGILGKDIFLQWALDMEGIICVRDGVNEVFNAGRSQTDEVGSCE
WLIGAGPGRMLTFWAVHCLDDISTMRSPRVTLWKSQEVMKPDLGSSSKNNGLRNSEGSYF
NKVVVWRNRRFGPPSVCSLIQLFPCNNLIWSVLYAQSLQKEYGESSNLCEMDSKLSCQSR
GVLDTLGHTGKVLQVAVHPSLHEVKLAVSLDSNGLLIFWSIFTSSNSFSGLPSLTPLWQL
RGKFILQNTVAQDMSLCWAPSWLEEEQILLIGYAQGIDCFIIKTCVTEENKILCHKFCTI
PFNKRDHFYGPDQVVSLPLPSCCKKDSNFNYYLLLGIWMKNFQAESWKVTLHSYELSESE
HSYESDTGSNGEYGVFKSKTDFAGKTYCMVASPCSTYIPDGLDEVTSFSVVSPRLSMYSL
QPKLVNDFCPSNFPYHMATGHSDGRSRIWRINLSDLSVGSTLFELVGIFSSLQCPITAIS
IADWGQKIATVCSDDINNVNMLYIWEPLHLAGAGTLVLEDKISLSGKVVAFNWFLMDNIL
FLGVCFQNELHIYSQRIRGAQTSLYLDKMQKESIWVCIGVVHTSSTICDFALGPRCTLIV
IHEKYFTLYSHWSLLTSDKHLTDGQLSADDAFDFKSQMDRNIPALSASKIQIFEELSVER
SSEDITIGSPLTKAHGDNIDTKPLIASPKKNHFSKMTVLAEILRGPLPFYHPEALLNNIY
SGNWARAYAAVCHLVQCLTPNTTANQSETPPISSLKLSKYFEGKLSNGEARGVQWSNDLD
TSTWSPPSEGGKMQFVESANNAINRMPTATAVSFGSYEFDEFLGKAQVRQAVTNAQKMQM
FAIVDLLYEISNIESTSAYESLDDPGKRFWCAIRLQQLEFRKRYSRAPSIAELVVNSRLF
VWAFHSDCQAILFSTILPAEPAWEDMRKLGVGFWFTNMTDLRSKMEKLARCQYLKNKDPK
ACALLYIALNRLQVLAGLFKISKNEKDKPLVAFLSRNFQEEKHRAAASKNAYVLMGKHQY
ELAIAFFLLGGDIISAITVCAKTLGDEQLAVVICRLIEGEGGASERHLISNILLPAAIEK
GDYWLASVLEWKLGSCLQSFLIVLGLQRDSYANESEINHAAFFDPSIGQYCQMLGAKNSL
RNAVGELNAAFLCRWTTMMTASAFNKCGLPLEALECLSSSVSIAGVLDKKQNGEDSEVLP
RILRPSLANSSRWLADEVACHLVSHVKLDLAMQYAVKLIKEHQCGLKTNVVLSRAGATAT
SWNSLEHEISQYGALLKNFKQELDSELAYLETKFSVVRDILLDKIFISLDNDGLLLKSYH
GSVSEVHSPASKNSDFTSFQLHHFENVTAYLSYSLPRFVVACIIARGWALASSELKWPVF
KPYWGFQSLEFYIPGFESSVLSLRTALMALSDDNSRNLVEQCFFALDLCKYCVYFALAML
QHNLKALDAMLQPVLVLCADGNYGEIDIISLREILNAVEAFSLKSSEINDLLGTQELLQE
NEGDMVFMTPEDEKWLVFRLCLWQHLSKFIKYQLNHLSSKLSCDATETSVVRSSVFPTPE
GKCSMNNVRQVLMNFIKTIGNTFTHVTSHTARQLAIFLWQKVEDGTSMPILTWLEEFSQS
TPSVFNDHQDQSCGTSEILDKETGFSCSKLLAKISHHPKLISEMLVQSPVKLSEVVHYKI
VKGWNHLHMCVLAEHEKLESYKQEGIFDNSPRGNKGKIHVGSEQNHNLLGPDFDGAALTK
KVVRFNNPKEIYRRSGELFEAFCINPIEQQQAALASNKKGISFFSWGDGLPSTDLSDYIW
QQSDWPQNGWAGTESTPVPTCVSPGVGLGSDKGSQLGLGGTTVGVGFQSKIGKDLTGGRA
FGIPGYAGIGSTGLSWGIQDEFDKCVDPPATLNNVNGSALAAHPSRPFFLVGSSNTHIYL
WEFGKEKAVATYGVLPAANIPPPYALASVTGLQFDRCGHRFASSASDGTVSAWQLEVGGR
SNVKPTESSLCFSGHVSDVCYVATSGSIIAAAGYSSTGVNVVIWDTLAPPSSSRASVMCH
EGGASSIAVFDNDMGTGSISPLIVTGGKSGDVGLHDFRYIATGKTKRHRHLNSVDRVMDT
AAIDIRSELSSSVGDQNRHGMLWYIPKAHSGCVTKIATIPNTSFFLTGSKDGDVKLWDAK
KASLVFHWPKLHERHTFLNRSSQGFGGVTRVGLTDIQVISDGFLTCGGDGTVKLVQLNNF
PS
>Sgl10903 ULD/UDP/UBQ/UBQ_PIM 85.9 0.1
MSSAGIAVSRIRAEEPLVSPRFFHNALDLNLAESIVVFLSVSGNMIPLRVFGSDSIESVK
LKIQCFKGFVAKSQKLVCGGRELSRSNSLVRDYGVANGNVLHLVIRLSDLQTVKVKTTCG
KELTFDVGRYRDVGYLKKQIAQRADEFDDVDDQELVYEGKPLNDQQLVDDICKNFDPVLH
LLVRKPFKFRVQRVEKNLDEWSLEAPELGRNREYDESADESVLVSSNVCEKDFILEPVVA
NPKAEIPSAILDVMERTCEGLESGNAPIRSNEGSGGVYFMQDSTGLEHVSVFKPVDEEPK
AMNNPHGLPLTSDGEGLKRGTIVGQGALREVAAYLLDHPSSGRRGVTGEVMGFAGVPPTG
LVSCLHQGFNHSNEVTHKMGSLQKFVKNDGSCEDIGPGSFPVEEVHKISVLDIRLANADR
HAGNILFRKDNETGQTVLIPIDHGYCLPECFEDCTFEWLYWPQARQPYSAETVEYIRSLD
AEEDIALLNFYGWDLPIQSARTLRISTMLLKKGVERGLTPYEIGSIMCRENIKVESVIEE
IVQEATDSVLPCSSEAAFLETVSQIMDRRLDEFSG
>Sgl10914 E3_adaptor/Cullin_RING/SCF/F-box 14 0.1
MRKRLKRNNVICSCNSPRSSFLSLRTSFCWYEDDVWFEIAKYLEGKSLVMLATTCKWFYK
TLSEECVWKFACLRDLGVLDPGNVSFKWKDLYASAFDGSHSYLFRQQEKHIDWIRIGAFS
LESSAAILTEKLTCPPRRIPQKETLEEMLQTCGFCVLTNIKTGIWIADLQLVRCPVCDLD
TCDGTMQTLDARHFELFMTGGYQDGSWDYTQIGVHETKKHVDGAAGAIFDMKHLKDSSTA
EIFNSKSWIGKKNDWQPKAKLTLHAVAVNTNLQDNEGINVKFHVMRAGTDGQIVAIRVSQ
QLL
>Sgl10915 E3_activity/RING/RING 31.3 12.0
MGFQTFSPFLTFLFSFILSSSAYSFCPTTTCKNDTLLPIRFPFHLEEQQPDNCSYPGFNL
HCSNQGRTVITLPHAGDFLVRHINYETQHILIDAENNCLPQKLLEGFDPSGTPFQADFYF
NYTFFSCPKHFSNGRSDVIDCLSNSTRSVFAVSATDVSAEMTESCQVIRSLLLPAISSEN
GGSPSSLSDDVWLSWFLPDCKECESRGGICGFHSNGNQQIGCFTDLRHSGDPAQTENSTG
LKIFRIIAFSIAIPAITCAVGVGIFLCIMDRRDRRSGAQVNRALQEVSATGQPLDTAMGL
DQATIDSYTKVVLGESRRVPGVNDGSCPICLSEYSAKETLRCIPDCKHCFHADCIDEWLK
LKGTCPLCRTSPADHAEV
>Sgl10916 ULD/UDP/UBQ/UBQ_Other 24.4 0.1
MAESNFIQFFVKIFDNKTLTLQFPSHQTLTPQSIKHQIESLTRIPIDSQNLTLNGKNLTN
SKQIAPKSLSFSTINLNFSLLGGKGGFGSLLRGAATKAGQKKTNNFDACRDMSGRRLRHV
NAEKRMEEWRAEEEERKMEKMAEEYLKKMEKKGKGGKKDEGAEKYVEKYRQQSRRCVEEV
ERSVRESVGELMSDRKKKRKLEKSKGGSENVDAKKLKIWMGKRKVGESDSDDSDSDRESD
DSDAENEKSVVTENGNQSDSSKDASSVSISALPLERENHSGGSSDSGSEVEKEMVNGGST
RLSATQSGNNGEVNGGSPVQTSSGEKMSASTEVLSTSAKTLVEQTPREYDSLASMISEQL
LSTITSVEPESHQLPTVDPELDQAPECKAVSSNEGVTGSSNASEALQPLTFDNINSATEL
EVLGMERLKSELQARGLKCGGTLQERAARLFLLKTTPLEKLPKKLLAKK
>Sgl10941 E3_adaptor/Cullin_RING/Cullin 452.3 6.6
MNDRKVIELQQGWEFMEKGITKLKKILEGLPEPPFNSEDYMMLYTQVLPSLREKHDEFML
RELVKRWSNHKVMVRWLSRFFHYLDRYFIARRSLPSLHEVGLTCFRDLVYQEISCKAKDA
VIALIDVEREGGQIDRGLLKNVLDIYVEIGMGQMDHYEKDFEVHMLDDTAAYYSRKASSW
ILEDSCPETLIYFWVLQSEECLKKEKDRVAHYLHSSSEPKLLEKVQNELLLVYENQLLEK
ENSGCRALLKDDKVDDLSRMYRLYSKVTKGLEPIGSIFKQHITDEGTALVQQAEDAAISK
AENAGGSHEQVFVRKVIELHDKFMTYVTECFNSHTIFHKALKEAFEVFLNKGVAGSSSAE
LLATFCDNILKKGGSEKLSDEAIEDSLEKVVKLLAYVSDKDLFAEFYRKKLSRRLLFDKS
ANDDHERSILTKLKQQCGGQFTSKMEGMVTDLTLARENQTNFEEYLGQNPDANPGLDLTV
TVLTTGFWPSYKSSDLNLPAEMVRCVEVFKQFYQTKTKHRKLTWVYSLGSCNINGKFGQK
TIELVVGTYQAAALMLFNTSDRLSYSEIAIQLNLADEDLVRVLQSLSCAKYKILLKEPSS
RTVSPTDYFSFNASFTDRMRRIRIPLPPMDERKKVVEDVDKDRRYAIDASIVRIMKSRKV
LGYQQLITECVEQLSRMFKPDFKAIKKRIEDLITRDYIERDKENPQLFRYLA
>Sgl10942 ULD/UDP/UBQ/UBQ_PIM 442.9 23.2
MQIFVKTLTGKTITLEVETSDTIENVKTKIQDKEGIPPDQQRLIFAGKQLEDGRTLADYN
IQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVETSDTIENVKTKIQDKEGIAPDQQRLI
FAGKQLEDGRTLADYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVETSDTIENVKT
KIQDKEGIPPDQQRLIFAGKQLEDGRTLADYNIQKESTLHLVLRLRGGMQIFVKTLTGKT
ITLEVETSDTIDNVKSKIQDKEGIPPDQQRLIFAGKQLEEGRTLADYNIQKESTLHLVLR
LRGGMQIFVKTLTGKTITLEVESSDTIENVKTKIQDKEGIPPDQQRIIFAGKQLEDGRTL
ADYNIQKESTLHLVLRLRGGDA
>Sgl10943 ULD/UDP/UBQ/UBQ_PIM 96.8 0.3
MSGQIYVETVTGETIRLDEESLDIVKAKVRNKEGIPQEHQRLVFPANRQIKTNSGTSSVV
ETHGNSSKSHDDTNRVMQIFVKTLTGKTITIEVKSSDTIFLVKARIWNKTGMPAEEQRLI
FNGKQLEDERTLADYKVCKEATFHLVIRLRGA
>Sgl10963 E3_adaptor/Cullin_RING/DCX/DWD 89.9 12.2
MPGNNNVQEIKMGGSELPSKQEDFPKMASPVIYDSMRGQLHGTSGHNCTDELENNSLEHC
GITFSGLEPPCVSTQSPEHTGRMVKTFKMEKHKDHGLDISNKDVHLRKGHWPHFYQMVGG
PKHTDFQGDPPSRVNDKLTINVGEDSKRSDIDAWNLRHLITKQDETGRVSVDAMHGKNMN
CESALLPQDARLKILSTSSFSQYFGKKTAKGKGVVSGQLGDKADFDSAGNLESNTRMFSN
ASMASDFCGGTLSQSVVNLREWLKPGNCVKDKVVSLSFFRQIVELVNLAHSQGAILEQLR
PSYFNIMSSNKLKYIGSSTQIDLPVPKSLTGCKKRSPEEDINVLCTSDVKQQRVLNHPSS
VTSKTRVSSAMHHELKCDAGSSSGSYNFANGSLSMPSCQATRLEKSPLTELHLEEKWYAC
PEELDARASKLSSNIYSLGVLLFELLCSFESLETHSSAMFDMHHRILPPFFLSENPKEAG
FCLWLIHPIPSSRPTIRDILLSDLLCGSHELKPSSESALSTNDFDSSESELLLDFLVSVK
DKKQDRAMKLVEDIRCIETDIKGLHGKSSLLTSQVHVKKDYNLQDFIKSIAKSGRNGDRL
KNDMSQLEKAYFLMRGQASATTGASRADRDLLKKREIWSQVQSQNNIVSKNQKSASGLDT
FFEGLCKFTCYSKLEVRGTLRNGDLLNSNNVICSLSFDRDEEYVAVAGASKKIKIFEYSA
LVNDAIDIHYPVIEIGNKSKLSCISWNSYIRNYLASTDYDGAVQVWDASTGMGYSHHTEH
QKRAWSIDFSRADPTKFASGSDDCSVKLWSTNEKKSTCTIWSPANVCSVQFSPYSSHLLM
FGSADHKIYGYDLRHMRIPWCTLSGHEKTVSYVKFTDSETLVSASTDNTLKLWDLSKTSL
SGMSSDACHTTFSGHTNKKHFVGLSVSDGYIACGSESNEVFTYYRSLPMPITSYKLSSIH
PVSQQDVREDDGLFVSSVCWRSKSNTILAANSGGSVRLLQLV
>Sgl10974 UBD/UBC-like/UBD_UBC 246.9 0.0
MASKRILKELKDLQKDPPTSCSAGPVAEDMFHWQATIMGPVESPYTGGVFLVTIHFPPDY
PFKPPKVAFRTKVFHPNINSNGSICLDILKEQWSPALTISKVLLSICSLLTDPNPDDPLV
PEIAHMYKTDRSKYETTARSWTQKYAMG
>Sgl10986 E3_adaptor/Cullin_RING/BCR/BTB 34.1 0.0
MRNMNRDLFDPRSVMDSEIDRSPKEGNFGFAFNDSNFSDRVLRIEIMAGPSDSKLDDACC
SLLDWARNRKRRREDLKKDVSNDINVNNNNNTNIDGTEVAVCPEEQVLNQSDGDDLLGCD
NDDEEAVAMVEEIPSGDDGENSNDSSWSMECSTVVRVQTLHISSPILAAKSPFFYKLFSN
GMRESEQRHVTLRINASEEAALMELLNFMYSNTLSGNTAPALLDVLMAADKFEVASCMRY
CSRLLRNMPMTPESALLYLDLPSSVLMAEAVQPLTDAAKQYLADRYKDITKFHEEVMSLP
IAGIEAILASDDLQVASEDAVYDFVLKWARSQFPKLEERRDILASRLARYIRFPYMTCRK
LRKVLSCPDFDHEASSKLVLEALFFKSEVPHRQRILAAEESASTNRRFLERAYKYRPVKV
VEFDTPRQQCVVYLDLKREECANLFPSGRVYSQAFHLGGQGFFLSAHCNMDQQSSFHCFG
LFLGMQEKGSVTFAVDYEFAARSKPTEEFQSKYKGNYTFMGGKAVGYRNLFGIPWTSFMA
EDSLYFINGILHLRAELTIRH
>Sgl10991 E3_adaptor/Cullin_RING/SCF/F-box 22.3 0.0
MDGDTWASHYQYRYVINPAKFDSFSDVTDEENKDIVSVDSALPDDLLERILAYLPVASIF
RAGCVCKRWNDIVSSKRFLWNFSANILSHKPWYFMFTSTDDSFGHSYDPALKKWYGIELP
YYVTSNWFIASSFGLICLMNNDNSTEVHVYNPITKCNKTLIEPSGLKSSDYSALAISVDK
LSHNYNVSIVKSKQVPDNFYQWDLSIHVYNSGTMVWVTTLTEVLNGWRAGDESVICGNAL
YFLLYSTGGGTPDNRHGLIKYNLSSQSSQGKLMRNFIPAPCSLTCGRLMNLKEKLVMVGG
IGKQDRSDIIKGIGIWVLNGTEWQEVARMPHKYFQGFGEFDDVFASSGTDDLIYIQSYGA
PALLLFDINYKQWRWSQKCPVTKRFPLQLFTGFCYEPRLEVSP
>Sgl11009 E3_activity/RING/RING 33.9 9.1
MSSTTTPPPPLSSHFSLSLQNLGLGYAIALAFGFLVLFSALLLSSYLCCRRRHHHHTRNH
RHHSSADSNTTIVPRIFFVAEDDDDDLENNNNSSSSNGVVGLDRDVINSYPKFHFYKKNL
ESYTSSMTDNLMMCSICLCDYKDGEMLRMMPDCKHFFHLNCLDAWLKLNGSCPVCRNSPL
PTPVSTPLAEVVPLSHYPDNRRSSSVVSSSS
>Sgl11018 E3_activity/RING/RING 33.2 7.6
MVAQNTFSKTICSICYEDLKPIVEDLQAISICGHVFHELCLQQWFGYCTNTKKQSCPVCK
QGCKDKDVGRLYFQSIGDPALSQSQTEVQKLSQSRDDESPELLRFEVKRLEVKVSGLNSA
LDLRQKDLKQVNDELQICKEQLSKEIVLKNEALSQRQCIQAMLQTKSNDLAKSNLECSKL
KERNLALVKEIATLKLVSDCNLEEEEIVKLATVGNESNSQDAIDVLKKSLVIRNKSYKEL
MAKCNSLGRGVARSLKKLEKAKDKIVKLKTRVRELETTIEEKDNEVLRSLKASKKRNCDD
VNLPSVHMQTNPSSVFKNSPVEDKGQSPTSVIDLDDEGNDEHLVVKENKKDATVGFKSDS
RTFQHKETRDYDCLIDDGDEPQKLRTGNPHSKAGDSKEGSSKKYKSFVSVDFDDKVDLVQ
QSNHQCGLSGFRNEVPVDHSATKEASGLVLQDIRQVQPSFMSTAEIPASIPLAEPGNRCF
SGGLLGPDGANRYLGKWCKRTQNKSPLGSNSDADALIAVGADGRGGRVKVLRSPNQILMV
GLLPFCLDTLRLMIPGINTCQDAKDSMVSAKRFKPGAKSSGLQSQGCRQIDHFFRKANN
>Sgl11040 E3_activity/RING/RING 34.6 6.1
MGFPVGYTEVFIPTLFLHTLTLFTFIRKFLFNFFHCFGLSDFLEPGPMAPIEPLPARITS
TPSPSLGPPPLSAILTRELLPLVHVSKEQEENESCAVCLYEFVSGEEIRWLGNCKHIFHK
DCLDRWMDLDHRTCPLCRTPFLLDDLLDQFNQRFLAADADDSCDLLQYVDHFNYTGF
>Sgl11047 E3_activity/RING/RING 35.8 5.3
MGGCCCSSRKSQLQGTPVYYYCPPTLEGQENLRACRGTASGLSTGLLVGPNLDTSSPDTF
RPPPAPIPFNVLFGRPQTPLRALGSLGPKCDAVKESKPSSIGVNTGADGSDLLIPVDRVG
KSEGRTLADILLASPTKSDVEISKPTEAYELAPEDEDACPICFEEYDSDNPKMVTNCDHD
FHLSCLLEWMERSDSCPVCDKEMIFDHPDDQN
>Sgl11051 UBD/UBC-like/UBD_UBC 107.8 0.0
MSSPSKRREMDLMKLMMSDYKVEMINDGMQEFYVEFHGPNESPYHGGVWRIRVELPDAYP
YKSPSIGFINKIYHPNVDEMSGSVCLDVINQTWSPMFDLVNVFEVFLPQLLLYPNPSDPL
NGEAAALMMRDRAAYDQRVKEYCEKYAKAEDAGAVPEEKSSDEELSEDEYASSDEAMVGQ
ADP
>Sgl11066 E3_activity/RING/U-box 88.4 0.0
MDLIILEDGNTSDIETGFKKLMKEDKLYVAVGKDVKENESLLSWAIQNSGGRIISIIHVH
QPDYFIPILGEKFHWSSLKEQQVTAYRGIEKQFMHKNLDEYLHYCRQFGVQAEKLYIEMD
SIEKGILQLIAEHNVEKLVMGAAADDCYYNKMTEVMSKKADYVQLHAPTKCHIWFICKGH
LIHQRKCSPRTKIHTQEMSIDSNSLSLMDQSTNRCAVRHEEVILGDGSSSHFGSSNGRVV
RSPSTNDIETTNGFGPAVDLEANCHNWSEILQLLRSEVNEFSAGSSSHTSRELTAEQLEQ
LADLFFEQNHHCHTSTAQRKLLQSVQREAVKKSKEFEEDLEKVKNDRDKLREELQDAMEQ
NLILESKVSNYDQVVKQLEEGFISNVELLQVCENERDDLKIQRDNVLKIAEELLNLSAEA
SSKTEVLKFLTTFTFAEIKEATNDFDPALQIWEGENGSIYKGVVSCTQVTIKIWRPEGLQ
GPRAFHQEVEILSKFRHPNMVVLVGVCPEAWAVVYEYLPNGNLQERLNSTSDTNLSWKNR
IKIATELCSALVFLHSRSPRRVIHGALQPTSIFLDSDFTCKIGGFDFSHMIPHHEEEESH
SPSREPLHCSLYTDFEYCTTGVATPAMDVYSFGLILLELLTGKPAFGLRDELEDALDGDS
FVSLLDTSAGEWPFVQAKQLARLALRCCMENGSDRPDLESDVWRVLEPMRISSGGSTSYR
LGDGPDGHRQAPPYFLCPIFQEVMKDPHVAADGYTYEVEALRGWLDSGHDTSPMTNLTLE
HFNLVPNHSLRSAIQEWRQRH
>Sgl11067 E3_activity/RING/U-box 77.2 0.0
MEQIQQERIYVAVGEDAEESESALNWALKLSEGDTICVIHVVVPAQKFPQPSSASQTSSN
AVGKVDVKEFQEWPRKEVVELVDEWLKMCDLNQVPYENFYVEKEVITEGILELISQLGIR
KLVMGAGVNNKKLRIKRPTSRKSNYVLQFAPVSCYIWFVSKDRLIYARNGMKQMNPNLEE
SSLYTPSAVSVVSLSPLSQKSRFKSENNENHQHNHNEQTLGEVERSRQETHEESETQKAF
NKVKSTKKELKHVIKGLKKIQIKLHTDSKKLLQEAGASSSLLERQVIDSILKGNETTEEK
LNTKMLQKYKKRCEEVKLECDNAIEAAQVLQKQVSQEPSSFPKFSCEFSQLDIQEATKCF
HPSLKIVERESYSVYKGFLYYTEVAIKTRKHDWCILNFDKEIDVLSKLRHPNLVTLIGTC
PDSLSLIYEYLPNGNLEDRLSCKDNTPPLPWATRIRIVTELCTVLNFLHSMKPCSIIHGQ
LYLRKILLDVNFRCKLGGFGLCHVISDDSSFLTGLLLEAGHLSTKSDVYSFGIILLQLLT
GRPTLKVVEEIQDALENDRLHSMLDTSAGDWPIIRAKQLAYIALKCCDVNPKDRPELGSE
VWSVLKPVITPSESLASPLQLLTEDRVPSHFLCPIFQEIMREPHFAADGFTYEGDGIRGW
FEGGNDTSPMTNLKLDNLNLIPNRSLRSAIQEFLLQHQRA
>Sgl11069 E3_activity/RING/U-box 87 0.0
MEDRNSPCSLSEAMELYDRLEKTMVELENSKLEASEESRRRHKAEKEALEASRHVNYVQR
LYLDELKKRTETCAELIEMKKDFEFTNSLLEKVTQELHEASEQKLSLESQLEKTYLSEKE
LEKKILSAVDLLQKWKNYHNELEEERDRALQEAEELRYQLAQHSQRPLRSHASNFDFSFA
ELHEATNNFDSALIIEEGEKGTTYKGVLHHIDVAITMLNPNTISGPREFEQEYLSRGSLE
DRLMRKDNTPPLPWKTRIEIAKQLCSILTFLHSRSPSSIIHGNLKPENILLNEKFVCKLH
GFCLDLKFPETEELTPAANVYSFGIILLRLLTGKIAFGLAYDVKDALDSDDLSVILDKSA
GNLPNVQAKRLASMALRCCDMDPNVHPDLNSEVWNVLESIKASSQPLSRLPLESEEEVPH
HFICPISLDIMEDPRVAADGFTYEAKAIEEWLKNYKNSSPMTSEKVANKILIHNHALRSA
IQDWLERCRSA
>Sgl11070 E3_activity/RING/U-box 92.8 0.0
MGSSRGFEGDARKIMVVDNKIFVAVCKELKESKSKLKWALENSNGKKICIIYVHVPAKVI
PMPMGGKFPVSQVGEKELQSFRKQENSEMLKKLDDYLQLCAQFGVRAEKIHITMDSIEEG
IVEIISQHKIGRLVMGAAADSRFSRRMVEPKSKKANYVCQHAPDFCHISFVCKGRLICTR
EGVRQPSLEVEGILSNSSSGDQLNASFLSQEFSGYDGSSDGFDKSSRISFSKSIHSAHSA
EADSVLSSPCSSISREEFREPGMELLALSPATNKRQDSSPPSVLQESSMNDDLYDQLVQA
TAEAESSRREAFDEAMRRQKAENEAMEAIRKAKAAERLYFKEIKLRKEKQEELEKRKEEL
EITKREWEKAMHELHEALDRKSLLETQYEKSKVSEKEMEEKILSAVDLLQKYRTEREELQ
VQRDHALQEAEKLRKQFAQEPSSSYVPFYFSEFSFSDLQKATNNFDPSLKIGEGGYGSIY
KGFLRHTEVAIKILNPNSMQGPNEFEQEVDVLSKLRHPNLVALIGACPESWALVYEYLSG
GSLEDRLVCKDNTPPLPWQTRIQIATELCSVLIFLHSSRPSSVIHGDLKPSNILLDDNFV
CKLGDFGICCVVSNSEQTTKFCTTQPKGTFTYMDPEMFTTGELTPKSDTYSFGVILLRLL
TGKPAMGIQKEVEYALDKGNLNCLLDPSAGDWPFVQAEQLARMALRCCHKTGKNRPELGS
DIWRVLEPMKASSRSLSMLRLASDDRAPHYFICPIFQELMEDPQIASDGFTYEAEAIRGW
LDSGHDTSPMTNAKLSNHDFVPNHTLRSAIQEWLQLHRCV
>Sgl11076 E3_adaptor/Cullin_RING/SCF/F-box 19.2 0.0
MATLPTEIITEILSRLPVNSLLRFKCVSKSWHSLIKNPIFIKLHLNQTLISSSDNFLLKW
NDFSSKIHLASLHFPHYHPFTFLELHHPLETQEFYFLGSCNGVICICNASKDDVVLFNPL
TRTQRKLPKDRIPLIFPSVSVFGFGYDSKSDDYKVLKIVQWFKLDQRFFKAQVYSVNNDS
WKSVEGIKHNLNLLYSDSHGVLINQALHYMVIEYGVALWSASASELLSKCKFIACFDLET
ETFSLIDCPNYDEELSASTSLKFHLMELGGYLSVCVNYRTSDHAHTLPPESADTGLSNHM
LFRADLWVMKVYGEKESWVRLFSICDVKSFRSVTCLKPVVYSKDGRSVLIVVDYMDVVWY
DLESKKVVRLESNGLQKESYDTVLFTGSLVSFQDKVHPKRSSLAMKNNKRQDLNNFLSTG
FKLKL
>Sgl11157 E3_activity/RING/RING 37.1 8.9
MSTNDADTTAPLLAPLSPTTGNQSFQSRSRRLSGRAGLRGAARFLRRTNSRRMMSEHSMT
VRESAAQQIEERQSDWAYSTPIVVLDLLWNTVFVLVSIVMMIISGDEKTEVPLRLWLIGY
GFQCILHMVCVCVEYKRRREVVRPRFGSSNGWGAGVVAAQGFGSSSNLNVNANPGSNRSS
YANSRSNSSSSASLEEDAMDFAAEAYQDDDNTSVAKHLESANTMFSFIWWIIGFYWVSSG
GPTLSDDAPKLYWLTITFLAFDVFFVVICVVVACIIGIAVCCCLPCIIAILYAVADQEGA
NREDIERLPKYKFRRLGQIEDKSGEIQGLGGIMTQCDTDTLIEHAISEEDSECVICLTSF
EDGSELRALPCRHNFHCACIDKWLQINATCPLCKYNILKNGNQSSEEV
>Sgl11176 E3_activity/RING/RING 40 6.2
MMYDINLITTVIGFGMSSIFIVFVCTRLICKRLQLTDSRGAVDTEPETDVEQPEQRTRTD
GLEPVVVAAIPTMKFHQDAFSSGEDSQCSICLGEYQEKEVLRIMPKCGHSFHLSCIDPWL
MKQSTCPVCRLPLKHSYDPKLGWLDDHVEPPMENTNQSFLPDARNSADNFGNQQHHQSTT
SSSNQELDLLGGSEHREGLT
>Sgl11227 UBD/UBC-like/UBD_UBC 115.7 0.0
MATNENLPPNVIKQLAKELKNLDETPPEGIKVGVNDDDFATIFADIDGPAGTPYENGVFR
MKLILSSDFPHSPPKGYFLTKIFHPNIANNGEICVNTLKKDWNPTLGLRHVLLVIRCLLI
EPFPESALNEQAGKMLLENYEEYAKLARLYTGIHAKPKSKLKYGAVSESTTALNVDNRNN
TSAQNADQKNNTLANTLAAPQSITASSKATSLHDQCASTTASTPSSNDNSRAVESSTAPS
VSVAPPAQKKDGVLKAQQAEKKKIDARKKSLKRL
>Sgl11230 E3_adaptor/Cullin_RING/DCX/DWD 30.2 11.7
MGTAWMECLQPVDTKSVYSKDFNALSYKFIAVLVASLALARNIQRSEIDRRTQVDMLTRH
RQATGSRAWRKLVHYLTEMNCLFGPFHDQLCNPERVFWKLDFMESSSRMKMFLRRNYKGS
AHIGAAADYEDDAAAPHDQQREISASNASVLAVEAISADALNEDDENVVVNNRTSIDFDV
EQHAGHHSRHAVGAESQTQVSSHSHDAPTTSGQDLSEDPSAVAPGYVPSERDERIMLELP
CSMVRPLRVVRGTFQITTKRINFIADYSEASSLGSELDHSLELRDQEKNRSWLISSLHQI
YSRRYLLRRSALELFMLDRLNYFFDFGTSEGRRNAYRAIVHARPPHLNNIYLATQRPDQL
LERTQLMERWARREISNFEYLMQLNTLAGRSYNDITQYPIFPWILSDYTSQQLDLSNPSS
YRDLSKPVGALNPERLKKFQERYSTFDDPVIPKFHYGSHYSSAGTVLYYLVRLEPFTTLS
IQLQGGKFDHADRMFADIAATWEGVLEEMSDVKELVPELFYLPEMLSNANAIDFGTTQLG
QKLDLVKLPPWAENPVEFIHKHRMALESDYVSSHLHEWIDLIFGYKQRGKEAIAANNVFF
YITYEGTVDIDKISDPVQQRATQDQIAYFGQTPSQLLTVPHIKRMPLAEVLQLQTIFRNP
KELKPYAVPMPERLNLPASAMHASSDSVIIVDINAPAACVAQHKWQPNTPDGKGAPFLFH
HGKATTSTSGGGFMRMFKGPAGAVSEDWHFPLALAFPTSGIRSSAIVAITNNKEIITGGH
VDNSIRIISADGAKTLETAIGHCAPVTCLSLSSDGNYLVTGSRDTTVLLWRIHSISTNNS
EPSTSTSTHTSNTGNASTSILVDKNRKRRIEGPILVLRGHLAEVVSCCVSSDLGVVVSCS
HSPDILLHSIRRGRLLRRLASVQAHSVCLSSDGILMAWNQTQHLLSTFTLNGIVVARVQL
PSSGSISCMEISFDGQTALIGYNCSEGEHSLDRSRSWNSKQQGLGSLSTVLDLKQEDSIL
DMVSPSICFLDLYTLKVLHRLNLQAGQDITAIALNKDNTNLLVSTVDRQLIVFTDPALSV
KVVDQMLKLGWEGDGLSPLIK
>Sgl11276 E3_adaptor/Cullin_RING/DCX/DWD 53.1 9.7
MNPLLPIILLTTILAAIIAFLIFGNYFKKQKSEVESLAKAQPNNNNNATSKKPSKSTVSS
KKSQFKHHSHASDKEQNKKHHPLDLNTLKGHGDLVGGLCFSSDGRNLVTACVDGVVRVFR
LDDISNKSFKFLRINMPAGNHPVAVAFLEDDSSIVVATQTLSGSSLYMYAEDKANSSNGN
KQQAKLPLPEIKWEHHKVHQKNAILNLFGTTARYGSADGSTIIASCSEATEIKLWHGKTG
KLLGTVDTNQLKNHMASISPDGRFMAAAAFTADVKIWEIVYTKDGSVKEVVKAMQLKGHK
SAVTCLGFAPNSDKMITASKDGTLKVWNINVRYHMDEDPKILRGFPIPLQDSNGATLHYD
HLSVSPDGKILAVTHGSTLQWLCAETGKVLDTAEKAHDGDITWITWAPKSLPAGNSESFI
LGSSGVDKKVKLWMAPSIHPS
>Sgl11329 UBD/Alpha-Helix/UIM 15.3 0.1
MLALKPKFCNLQACNGRFLICSLLSLCQVRNRKLKSDKQKSLQKQLHKTEFTDEDDALKQ
AIALSLNDYGQTSDLQHAGLSRCSKNQSDTMSRNEKRKTKIFKSRVQMTEDDLVINFCQF
DEVGKGNITLRDLQRMANSHDFIWTDKELADMVRCFDSDRDGKLSLDDFRHIVLRCNMLL
VPENP
>Sgl11377 E3_activity/RING/RING 25.4 8.2
MASTGEADRKRRQVSSISPTAAGGMAKKQPFAPVSEDKKLDIAVLKFQNQKMSEKVEVQN
LEIMALKKRVAQQIEKQQSFEKMYTAFNNCSNKLLDGMEARSVHIRNLVCGEGNSHHPGV
MEDGSSSSDADPFLKRLKESYAPEPCLASNTVDQMLDDGDKASQKARNIVRNILAAVDVL
CRNKDDLYAAVLTALPEDGSCNRKAYEDMVAEVKNLQLAISDLLLKHRSLTRELRKHQVI
DMKNKAELKYLREMLECTIADLEESNQKLSAIKAEKDATEGAFFPVLNMGIKHGSNDRTT
DKQKDLQDMEVTLKESMDQSSSRLQELKQLHEERIEILKKLSDLQGTLKNVKSISCAPAF
KLLKEELEKSKADVIKYQALFEKLQVEKDKVTWKEKEVVVRTDTGDVFRRSLTTTSSRID
ELETEIERQNVERKRIERKLEEASREPGRKEVISKFRELVSSFPEDMSSMQSQLHKYKEA
AADVHSLRAEVQSLSNVLARKAKDLETLSSKSAEQDCEMGRLQALVQDLKESDMELNLIV
EMYRRESSVTRNLQAARDREYRAWARVHKLKSSLDEHNMEIRVKSAIEEEALSQRRLAAA
EAEIADLREKCESSERNKSTLSNALNSKKEENEAYLSEIETIGQAYDDMQNQNQHLLQQI
TERDDYNIKLVLEGQRSKQTHDLLLMEKQSLQKKIQHASVLRDFFEMKTSKIEDQVKGCS
DQVHRLAEDRCQNSVSLENIQRRLLEGRKASHQGKESLDELQNKVKDSRANLSGLQIELE
KERFEKKRVEEELEAMKRKAERLREQNESSVAGKLRQELQQYKEILKCSVCRDRPKEVVI
TKCYHLVCDPCVQKVIESRNRKCPICAASFGPNDVKPIYI
>Sgl11401 E3_adaptor/Cullin_RING/SCF/F-box 12.5 0.0
MSRRVRRKVAKKGKEKLLIPSYPELIIDENDEEEDDDDLLHSNFPINPTSNSQKPQKNNS
INPRNDFVDWTRLPDDTVIQLFSLLNYRDRASLSSSCKTWRNLGFTPCLWESLDLRAHRC
DFNTAFSLSSRCWNLRRVRFLGADSADAIIHLKARNLTDISGDFCRKITDATLSVIAARH
EMLESLQLGPDFCERITSDAIRAVAMCCPRLRKLRLSGVREIHSDAINALAKHCVHLSDI
GFMDCLKVDETAMGNLSSLRFLSVAGTSNLKWGLVSHLWSKLPNLIGLDVSRTDVSPTAV
SRMLLSCQTLRVLCVLNCVHVEEDANFLTSRSVGSKGKLLLSLFTDIFKGVGSLFADNSM
KGRNVFLDWRDTKRDEKNVDDIMSWLEWMLSYSLLRIAEGNPQGLDNFWVSQGATLLLSL
MQSSQEDVQERAATGLATFVVIDDENTSIDGQRAEAVMRGGGVQLLLNLASSWREGLQAE
SAKAIANLSVNTNVAKAVADEGGITILANLARSMNRLVAEEAAGGLWNLSVGEEHKGAIA
EAGGVKALVDLIFKWSTGGDGVLERAAGALANLAADEKCSMEVALSGGVHALVMLARNCK
FEGVQEQAARALANLAAHGDSNSNNSAVGQEAGALEALVQLTHSAHEGVRQEAAGALWNL
SFNDLNREAIALAGGVEALVALAQSCSNASPGLQERAAGALWGLSVSEANSIAIGREGGV
APLIALARSEAEDVHETAAGALWNLAFNPGNALRIVEEGGVPALVHLCSSSVSKMARFMA
ALALAYMFDGRIDEVALAGTSSDGMSKCVSLDGARRMALKHIEAFVLTFSDPHAFAAAAA
SSAPAALAQVTEAARIQEAGHLRCSGAEIGRFVAMLRNPSSILKACAAFALLQFTIPGGR
HAIHHANLLQNAGAPRVLRAAAAAATAPLEAKIFARIVLRNLEHHLVEISI
>Sgl11419 E3_activity/RING/RING 26.2 8.4
MAEEDEILMEVEAVEAVYGDDCIILNRFPPHLHLHIKPRTADVDSQQFVEATIELRAGPQ
YPSDPPYIAIIGSKGLNEERQMHLSNSLHDKAHELTSCLMLVGLCEDAVEILNSMNHPEG
DCPLCLYPLVLEDIHSEAQPFMKLMSCFHCFHCECIVRWLTWIQKQNEASCGTSSTLLSD
VNEENDLVSDLHKLMGGSTGNCPVCRKVFLAKDIEHVLNSVGSYDADSDVYEKELVEKVL
QCDLETGRRQEFEAILKLQQQCGGLIEPPKDNVLYSRICIQDLVREDNEVMNREASEQHT
NQIVVEEPASSSSSNQASRRAGETRKQHRRGHRAVVEPASNAPPTGSGTGHRRHSGTRKH
GRDNSRWQVKPCSKE
>Sgl11459 E3_activity/RING/RING 34.4 9.6
MVRRRLLDDAHQSGNDVSPNILITVLVLAIAVILSASLYLLLRFFRRNNNNHSHSHSRHR
PHSLSSTNRHVISRRVTPENKAHNSLMEALPLFTSESLKTTGDCAVCLSKFEQKDLLRLL
PICCHVFHADCIDTWLNSNQSCPLCRSPVFLPDSELLSKLVPQQQDTSSVSSGSFRVEIG
NVSRRNENSGEFPVRRSYSLGGNFDYIVDDDVVSEVHSGSFRRTSSTTEFKTDTENNNNN
LQQQSALAAEVGTRGGGGGGGWLKDYLTHSLSSSFRSSGRWFFTGSSRRETTTTNEFGES
EMDLEASRLGDEIGELFRWLSGV
>Sgl11463 E3_activity/RING/RING 24.7 14.2
MEILHELMGKFVIFISTMVAIFPVLRRFLRHKGCLPATTYRGRSNEEGVFCMVCYDWVSR
GERVRVMPKCKHCYHVECIDAWLDSHCTCPICRDQVIHALHQQQRVKRRNVIVSLLIIVE
DLSTKFGYPLDFGMSLLMSSCV
>Sgl11470 E3_adaptor/Cullin_RING/DCX/DWD 136.1 24.1
MEEEEIEKAVIAYLKKKGFKQTELAFQEEQLQQQPQQSKNSSSNSQTDPDVAKLILTFSS
ESESLPAQYHDGYSKLRSWAYNSLDLYKHELLRVLYPVYIHCFMDLVAKGHLQEARTFFN
TFREDHETMHQRDLLKLEGVLSPSHLEEMEFAHTLRQSKVNIKICQYSYDLLIQYLHKDQ
SMTMLGVINEHINFEVFPGQGGSIFDDAEAVMLVDGGQDAANLINQKEIQWGMLEDSIED
RLEKNGGLLLDSEKVDGDNKEGENEENKKRSADGGKPGALVKKTKKDKVGGAGGKSARPE
ANTPTMAPRVKPELSLPVVPTEVEHSILEDLRNRVQLSSVALPSVSFYTFINTHNGLNCA
SISHDGSLVAGGFSDSSLKVWDMSKLGQQMGSSAHQGESAAGNEQMLGANGGKRPYTLFQ
GHSGPVYSASFSPLGDFILSSSADSTVRLWSTKLNANLVCYKGHNYPVWDVQFSPYGHYF
ASCSHDRTARIWSMDRIQPLRIMAGHLSDVDCVQWHVNCNYIATGSSDKTVRLWDIQSGE
CVRIFIGHRSMILSLAMSPDGRYMASGDEDGAIMMWDLASGRCITPLVGHTSCVWTLAFS
GEGSLLASGSADCTVKLWDVNASTKMLRSEEKSGSSNRLRSLKTLPTKATPVYSLMFSRR
NLLFGAGALSKPS
>Sgl11473 E3_activity/RING/RING 36.9 5.8
MASTTPISIGAPQPWLSPSPSSSPPPSSSKAYNYGYDCSVALCSINCPQFCSVFPPPPPL
FLNNSSDGDDSSSSRISPLMAALIAVLAAAFLLLFYFTVISRFCRNRRRRHNNNRLLNSN
RVDSLIHDPTRPETATTSGLDDSFIRQITVFKFRRSDKLIEATECAVCLSEFNEEENLRL
MPNCEHAFHLPCIDEWLKSNSNCPLCRSSMNPAPPPPPVRSTASVAALRVQRSNDAVLVI
REYPLQLVVDPTPQPPSTQNDDRHHQVGSRECRNNHVDESETKLEINNNNSR
>Sgl11480 E3_adaptor/Cullin_RING/DCX/DWD 33.4 2.6
MEDGNTRQYGVPLYGASWVPYNAIRSINPNSDDVDADNSAVTSPEILVVAGGGGEGNSGI
PNAILLSQYDSSTNSLSPQPIFRLGTDSELPYRIAVHPRGDGIICAFPNGCRWFDWEMTN
SNGDRDLSLRSTDKVHTRLEGVCQQLALTFSEDGSLLAVGGEDGKIRVFKWPSMDVLVDE
NEAYIEVKDLHFSIDGKHLVSVGNGGPCKIWDVASSKVVASLRKENDENFRFCRFSQSSE
RDQVLYTLATGGKGVSIISWNTKSWKRIAAKHITRDPVSAFNVSIDGKLLAIGTVEGGIL
IINSSKMQVQMTVKTAHMGLVTALTFSHDSRALGSTSMDSSVTVTLVQDNSANGTKNWII
MFVILLAIAVYFLKSQGFLPAGLPFSLSD
>Sgl11507 UBD/UBC-like/UBD_UBC 83.2 0.0
MTSSSTQSPKALSKIAQLRLQKELVEWHDPPVGFKHKVTDNLQRWVIEFSGAPGTLYANE
TYNLQVDFPEHYPMEAPQVIFVPPAPLHPHIYSNGHICLDILYDSWSPAMTISSICISIL
SMLSSSTSKERPADNDRYVNNCRNGRSPKETRWWFHDDKV
>Sgl11512 E2/UBC 73 0.1
MTSSSTQSPKALSKIAQLRLQKELVEWHDPPVGFKHKVTDNLQRWVIEVSGAPGTLYANE
TYNLQVDFPEHYPMEAPQVIFVPPAPLHPHIYSNGHICLGTYLFESGEKKVA
>Sgl11581 E3_activity/RING/RING 21.7 1.8
MGSACCVPARDATLSNRRRIGESQRPVRYSPTWSFRWDNYRRVAGEIENPCQSSERTSVD
VRMALKDSVGSDREIVSDGGSPLDNLGTPISQKSPSYEGVSTNYMSPSETSTTSNHFSKV
KNSIEVPEIGAVPATLQYSMPSCSSFSTPGEPLCLQRQLLPASSTPSRRARRSPGHQLFR
QISDSRILGLKSPNSNSVSEGRQSFVLSTYSNDLVGGSSDGWSLRTFSELVASSQRERWS
FDSERFGSGRHKISESSSRFSYSPSLDLQTCGACLKVMAELSVIAVLACGHVYHAECLET
MTTEGEKYDPVCPICTVGQKQASKMSRKASKAEADLRMKFQKISRNRVIDSYLDGEVDNP
GRQKIIAKGKFPKMESSSSSRISFAKPFLKRHFTLGSKLGKSNSEHQSGKKKGFWARYRR
D
>Sgl11594 UBD/UBC-like/UBD_UBC 84.7 0.0
MTSSSTQSPKALSKIAQLRLQKELVEWHDPPVGFKHKVTDNLQRWVIEVSGAPGTLYANE
TYNLQVDFPEHYPMEAPQVIFVPPAPLHPHIYSNGHICLDILYDSWSPAMTISSICISIL
SMLSSSTSKERPADNDRYVNNCRNGRSPKETRWWFHDDKV
>Sgl11621 E3_adaptor/Cullin_RING/DCX/DWD 126 14.0
MLTKFETKSNRVKGLSFHPKRPWILASLHSGVIQLWDYRMGTLIDRFDEHDGPVRGVDFH
KTQPLFVSGGDDYKIKVWNYKLHRCLFTLLGHLDYIRTVQFHHESPWIVSASDDQTIRVW
NWQSRTCISVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKSVSPADDLLR
LSQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKIWRMNDTKAWE
VDTLRGHMNNVSCVLFHSRQDIIVSNSEDKSIRVWDATKRTGLQTFRREHDRFWILTAHP
EMNLLAAGHDSGMIVFKLERERPAFAVSGDFVYYVRDRFLRVYEFSTQKDTQVIPIRRPG
STILNQSPRTLSYSPTENAIMIASDVDGGSYELYIIPKDGLGRGDMVQEAKRGLGASAIF
VARNKFAVLERSTNQVLVKNLKNEIVKKVALPAIIDAIFYAGAGNLLCRAEDKVLVFDPQ
QRIVLAELQTSFVRYVVWSNDMESVALLSKHSIIIATKKLEHRCTLHETIRVKSGAWDDN
GVFIYTTLNHIKYCLPNGDNGIIRTLDVPLYITRVSGNTIFCLDRDGKNRVISIDATEYF
FKLSLLRKRFDQVMGMIKRSELCGQAMIAYLQQKGFPEVALHFVKDEKTRFNLALESGNI
EVAVASANVIDDKTHWYKLGVEALRQGNADIVEYAYQKTKNFERLSFLYLITGNMEKSYK
MLKIAEVKNNVMGQFHNALYLGDIQERVKILEAAGQLPLAYITAKSHGLDDVTERLAAEL
GDEIPEIPQGKSQSLLMPPSPISCGANWPLLTVMKGMFDGLGYEKDAQEDEDEEVVDTWS
EALEIIDDDMVNGVVSADDGEEVDDEDEDAGWDLNLELPPEVETPKMSNGRSSVFNAPSP
GMPVSEIWKQRSSLAAEFVAAGSFDTAMRLLTRQLGIKNFAPLKPLFIDIFSASHSYMLA
FPSAPVISVALERGWSEASSPNVRGPPSLVFSFSQLEEKLRAGYKLTTAGKLSEALKTFT
NILNTIPLIVVETRREVDEVKELVIIVKEYVLGLKMELKRRELQDNPVRQQELAAYFTHC
NLQVPHVRLALLTAMKNCYKAGNLSTAANFARRLLETNPSVENQAKTARQVLQAAERNMK
DSTEINYDFRNPFVVCGATYVPIYRGQKEVSCPYCSSHFVPDQEGQICAVCDLAVIGADA
SGLLCSAAQKR
>Sgl11652 E3_adaptor/Cullin_RING/DCX/DWD 73.5 9.8
MSQKRPPPDPIAVLRGHRASVMDVCFHWCKPLLFSGSSDGELRIWDTVQHRTLSSAWVHS
AAHGIMCVASDPCIGDDKILSQGRDGTIKLWEIGNGGICRTPSVTFGTNSYHFCKLSMVK
KPINQKQKHVAGSGDVAADLVRDSTVNTLENQSEHSNDVQIEGAQYVVVAGEQPSQVEIW
DLNTAERCARLPEVSSDGLANGSEKARGMCMAVQAFIPPQCQGSLHILAGYEDGTMAWWD
VRNTMKPLTSVKYHSEPVTSLSVDQSCNGGISGAADDKIVLFNMDYDRGTCVVRKEISLG
RPGIAGTSIRSDGKIAATAGWDRRVRIYNYRKGNDLAILKYHSAMCNAVSFSRNCKLLAS
SSEDTTIALWELYPPRNTTGAACTHLRGREY
>Sgl11682 E3_adaptor/Cullin_RING/BCR/BTB 29.7 0.0
MLEIEMEESRSGTINISDVSYDALRAFVNYLYTADASLDEQMACDLLILAEKYEVKHLKT
YCENFLVSKLNWDNSLTTYSFAHRHNAKRLLESALSMVIDKMENLTKSEEYAHLVQKDPR
LIVEIYEAYMSKQLNTVARIG
>Sgl11684 E3_activity/RING/PHD 57.7 43.9
MVIEENGNGNGNDTGTVNGSSNSSSGKTVNVFLHGSSSGSDGFAADGSSLRTYKRRKCGL
SSSNTKIIDLEKPPCSTSAPLDDNNKMVKELVDIGLQKNSCEQVSDSKINCPSLLNGSDD
GSYQHWRNALESIFQSVCPTENGGGGVLDCITEALLRNPTNTDKETLYHCHSQSHMQSTG
MSNGFFSASEGISSVISNGASSESGHSSVSRQCQLVFYRLLMSGKFALLCKMLSENFHGL
KIEKLLEFGPINSRIKEGAYESKPMLFSSDIQQVWTKLRLIGSEMVSLSNNMSQLSRAFC
HDLAGGAAFDTSSEKRRKLSCRKYDVRVKQEEQDPSVFCTCRKCGERSDGRDCLVCDFCE
GMFHVSCIKPAVKEIPLKSWYCANCFASGNGSPHEDCAVCEQLIATCGVNGVDAVPVSEA
VLIDDHDEESSDGVIETGVQIFKGSKQLFCKLCGSTLNEGEEYRMCEHPFCMYKYYHTRC
LTNKEMTTYGPHWYCPSCLCRGCLTDKDDNNLVMCDGCDHGYHIYCMNPPRTSIPKGKWF
CSKCNVGIKAIRKVKKLYDNLEKKQIKDEGKCVGSPSNKSKEGFENAGGGSGGVDMLLSA
ARKLNDETDGNR
>Sgl11686 E3_adaptor/Cullin_RING/SCF/F-box 19.4 0.0
MARQQGLRTEDLDSFKKLMVFGAALDEMGGETTAEWKDIPMELLLRIMNLLDDQTVIKAS
EVCSGWREAIGLGLTHLSLSWCKNNMNNLVPSLVPKFANLQSLILRQDKPQLEDNAVETI
ASFCHDLQELDLSKSFKLTDRSLYALAHGCPNLRKLNISGCSAFSDAALAYLTSYCKKLK
SLNLCGCSGAATDKALQSIAYNCKELQTLNLGWCENVGDLGVTSLAYGCPNLRALDLCGC
VLITDESVIALANGCPHLRSLGLYYCQNITDRAMYSLAQSRVRNKHGVWPSIKNRYEDDG
LMSLNISQCTALTPPAVQAVCDSFPSLHTCPGRHSLIISGCLNLTSVHCACAIYGHRAAS
TIAH
>Sgl11724 E3_activity/RING/RING 34.5 7.3
MSNAAYGGRRASRRIAETNQIEGGASILTSKNGGGSNTEAMKLYEAIIFSGPIVFTLIIL
FLFYFFYLRRSVDWSSLRMRPTNSAAATADSDDLEVAELGLKKEFREMLPIIVYKESFSV
RDTRCSVCLGDYQAEDKLQQIPGCGHTFHRSCIDHWLATHTTCPLCRLSLVSPSKTPPTS
ERDSQESQDQADNNNDSTENVDDVLQQNRVQVLSVHTVV
>Sgl11746 E3_adaptor/Cullin_RING/DCX/DWD 26.1 8.1
MAQFLFQNDELEFIDDIYQMTNFEDELLGFSDSSTPRTNRSNNDDDDDDSFDSDVDDDFD
FCEGQGKLKSDTTSMEARNGIDIQGIPWERLNFTRDRYRETRLKQYKNFESLPSSSRQQE
LAKECKQVKKGYTFYDFQFNTRLIKSTIVHFQLRNLLWATSKHDVYLMQNSSVMHWSALC
KRSKEVLNVARPIVPTTKCLQSLPQPLSRVQISTMCVKDNMLVAGGFQGELICKYINQQE
VAFSTKVTTEENAITNAVDICNSSSGSKWVIVGNNDAHVRVFDSANFVCFNQFRFPWSVN
STSVSPDGKLMAVLGDSTECLVSDSHTGKVIGTLKGHSDYSFASAWHPDGQILATGNQDT
TCRLWDIRNMSQSLEVLKGRMGSIRALKFSSDGRFMAMAEPADFVHIFDTKSGYEKAQEI
DLFGEIAGISFSPDTEALFVGVADRMYGSVLEFNQRHCNGYLEAIF
>Sgl11808 E3_adaptor/Cullin_RING/SCF/F-box 15.9 0.0
MVKCYPFEKDIIFGGGRKVKMNEEEGNEIRQWDELIPDALGLIFKKLSLEDILTVIPRVC
KSWGKAAQGPYCWQEIDIDEWSTDCQRDKLDRMLRLLITRSSGSLRKLHVSCVNNDQIFS
FIAENAGSLQSLMLRRSEISDSIVEQLAGKFSKITSLDLSYCCRISTSGLEAIGKNCKLL
SSLSWNMHPLASAYNKPSHVDEARAIAQTMPKLKQLEIAYLQINKESVYDILLGCPNLEF
LDLRGCWNVHLDKKALEKRHPKLAVLGPQVVMGAFEKQAFFDDYYSDSDFSDYGYMDYSD
DESFDGMWDDEELEFRVYEGADYMYEFGWPPSP
>Sgl11828 E3_activity/RING/RING 22.3 8.9
MARNSTLSPDSNSVDAALLQYQNQKLAQKIEVQKQEVHDLEAKLQELKDRQSSYDDLLTN
VKQVWNQTIDDLVLLGIKAGGGLDVLQTSDSEDCIQGSTTSFRAEDFFLSRLLKVESMEG
EGGESCFKFDEEFLEQHLFSFLKLLKCVEDFVEDQQRTTNCVTQESKEILSVEGPGDAIK
SNKFEDLMTECAKFLHILVDDLRQKHSDYVDRIQRYVQSQSEDDAEIKHITGDIEESVAE
AEESRRKLGHLRMRKNLASGNYNPATAVNGTLSSYKVPDRSMGLQELKDSIEEAEILAID
RLAELEDGREDNAIMLKQLQEIENEIKDDKYVSSSRLYTLINDQLHHWKAEITCYKALTD
TLQSERSYIIRREKELELKTESADHAKATAGNAETRVEELELKLRDSVIEKNELEGKMEE
AVQDSGMTDIKTEFNVMASALTKEMGMVEAQLNRWKDIAQEAFSLREEAESQKTLLNRKT
SEVKSLGDKCAQQMAESKSLKELTEKLQKEKFELQIFVDMLGQGCYDNRDLSEIEESERR
ACAQAEVLKHALDEHNLELRIKAANEAEAACQLRLSAAEAEIADLRARLDMAERDVYELT
EAIKIKDAEAEAYISEIETIGQAYEDMQTQNQHLLQQMAERDDYNIKLVSESVKTKHAVN
SLLSEKQTLGHQFQLINTALESLREHILRSEEQMKTTMSEALSHCQEDRHLSVSLERAKW
ELSDLEKELKWVKSVMTSSEKEREQVQRKTVEIQRDLDIDRHDRKKLEEELKEWKDKVAE
LTAETGEAAILKLQEEIKECKSILKCGVCFDRAKEVLIVKCYHLFCNQCIQRNLEIRHRK
CPGCGTAFGQNDVRFVKI
>Sgl11833 UBD/Alpha-Helix/UIM 14.4 0.1
MATLRSTLPSRLRQLFGSEGSFGPSIQLDSETPPKIKAFIDKVIQSPLQDLAIPLSGFRW
EYNKGNFHHWRPLFHHFDTYFKEYIAKRNDLLLSDTITEDDASFPKHAVLQILRVMQIIL
ENCHNKSSFDGLEHFKLLLASTDPEVLVATLETLSALVKIPPSKLHVSGKMIGLGSINSC
LLSLAQGWGSKEEGLGLYSCVVANEKSQEEGLSLFPSDAPDRDEKSQTRLGSTLYFELHG
VSPQRSGESSSDVKPSSSTMIHMPDLHLRKEDDLLLLKQCIDQNNVPPEQRFSLLTRIRY
AHAFRSPKSGRLYSRICLLAFIVLVQSNDANDELVSFFANEPEYTNELIKIVRSEETISG
TVRTLAMLALGAQLAAYSSSHDRARMLSGSSINFAGANRMILLNVLQKAISSLKNSNDPS
SLAFVEALLQFYLLHVISTSSSGSIIRGSGMVPTFLPLLEDSEPAHMHLVCYAVKTLQKL
MDYSNAAVTLLKDSGGVELLAQRLQIEVQRVIGTGKSDDNLMVIADVSTEDYLYGQKRLI
RALLKALGSATYAPLNASSSQSSHDSTLPSTLSLIFGNVEKFGGDIYCSAVTVMSEILHK
DPTCFAILHEMGLPDAFLSSVVAGVLPSSKALTCVPSGLGAICLNTKGLEAVKEASALRF
LLEIFTSKKYVVAMNEAIVPLANGVEELLRHVSSLRSTGVDIIIEIINKISAFGEGSSSG
SSEKVNEGKIMELESGDKGSGSESSSSVVPSSDSAGEGITDEHFINLSVFHVMVLVHRTM
ENSETCRLFVEKSGIDALLKLLLRPSITQSSEGMAIALHSTMVFKGFTQHHSAPLARAFC
SFLRDHLKKALTGFSLVTGSFLLDSKTKLDHEVFSSLFLVEFLLFLAAAKESRWISALLT
EFGGESKDVLEDIGKVHREILWQIALLEDAKVEVQEGAGPASASEPQQVSSSSGAEEQRV
TSFRQLLDPLFRRRMSGWSVESQFFDLINLYRDLGRASGVQRSTSDGLNLRLGSSQQSRE
SGGLDTDSVSRKEEDKQRSHYTSCCEMVKSLASHIMHLLQELGKSMLLPSRRRDDAINIS
PSSKTVVSSFASICLGHMNFGGHMSPSGSEASVSSKCRYFGKVVDFVDGILMDRHDSCNP
VLLNCLYGQGVIQSILTTFEATSQLLFTVPSSPMETDDGNLKHDKKEEPEHSWLYGPLAS
YGKLMDHLVTSSYILAPFTKHLLVQPLPNNNTPFPPDAETFVKVLQSMVLKAVLPVWTDP
QFVDCSYAFITSIISIIRHIYSGVEVKNVSRSTTSSSRLPGPPPNEAAISTIVEMGFSRA
RAEEALRQVGANSVELAMEWLFTHQEEVPEDDELARALAMSLGSSGSDSKEEAASENSQQ
FEEEMAKLPPIDELLLTCVKLLQSKESLAFPVRDLLMTMCSQNDGQYRPNVITFIIEQIK
HCNSVTDRGNGSMLSALFHVLALILHEDAASRETCLKNGLVELVSDVLWQWDAGSSSGTD
ALVPKWVTAAFLAVDRLLQVEQKLNPEVVEVLKRNTETSQQASIVIDEDKQNKALEPSQQ
NVDVDQQKRLVEIACNCIRKQFPSETMHAVLQLCSTLTRTHTVAVSFLDSGGLPLLLNLP
TSSLFSGFDNIAANIIRHILEDPQTLQQAMESEIRHNIVTATNRQSSGRLTVRNFLVNLS
PVISRDPVVFMRAAQSVCQVEMVGDRPYIVLLKDRDKDKSKDKEKEKSLGTDVKPATGAV
APMALGGGQGKLQESKSFKAHKKPPHSFVNVIELLLDTVIMFEPPKKDDSLPEASGSLST
TNMDIDVAASKGKGKAVASESEEKEGQNQDVSASLAKIVFILKLLTEILVTYAASVHVLL
RKDVELSSCRGLPQRGTSGHNSGGLFHHLLHKFVPYCKKAKKEKKLDGDWKQKFASRANQ
FLVAACVRSAEARRRIFTEVNSVFSDFVESAEGFISPGNDIVAFVDLLNEVLGARSPTGS
YVASEASATFIDVGLVKSLTRTLQVLDLDSADSLNVVTGLVKALELVTKEHIHSADANAG
RHDNSAKPSDLERTDNSGDGVQAMEAASQENDNSATDVRGDSFNDGHAFGFSEAVTDDME
HDQDLDGGFAPNEDDYMHDTPVDGRGLENGVESVGIRFEIQADGQENLDDDDEMSGDDAD
DGDDDEDDEDDEDEDEQNDLEEDEDHHLPHPDTDQDDHEMDEDEFDEEVLEEEDDDDEDD
EDGLILRLEEGINGINVLDHIEVFGREHSFANETLQVMPVELFGSRRQGRSTSIYNLLGR
SDNTVPSQHPLLVESHPSSVPATSRASENTSDLLFSDRNAEGASSRLDTIFRSARNGRQG
HRFNMWLDDNEQSGGSNSSTIPQGLEELLVSQLRRLDAEQPSDQKAGVDSERNIEPDQLQ
VSETSMGIETPVGSNANNQSLYPPIPSSVAMDSLNPENRLGPASPRQGTDASSMHSQSVE
MQFEHNDVTVRDVEAVSQESGGSGATLGESLRSLDVEIGSADGHDDGGDRHGSAERTPLG
DSMGTRTRRNTVSFGVTPPVGGRETSLHSVSEVAENPNQEAEESGPADGQQMTGDGESGP
IDPTFLDALPEELRAEVLSAQQGQVTQPAGAEQQNSGDIDPEFLAALPPDIRAEVLAQQQ
AQRLHQSQELEGQPVEMDTVSIIATFPSDLREEVLLTSSDAVLANLTPALVAEANMLRER
FAHRYHSRTLFGMYPRSRRGESSRRGEGSGLDRAVGSIASRRSVVGKLLEADGAPLVDTD
ALKGMIRLLRVVQQVYKGSFQRLLLNLCAHSETRTALVKILMQMLMLDEHKLGNQQNDAE
PPYRLYACQSHVMYSRPQFVDGVPPLVSRRVLETLTYLARNHPYVAKILLELTFPQQAHI
PSESGDKVRGKALMVVENQSSDIHEEHCHSVALLLGLLNQPLYLRSNAHLEQLLSLLDVV
IDNAASKSSSSKLESSAPEQQSVSESPTTTTDVEMHATESGTNSSEAVTGPKVEESVVPS
VSGASDSYDARTVLLGLPQADLRLLCSLLATEGLSDNAYSLVADVLKKLVAFTPTHCHLF
ITELANSVRKLSQSAMVELHSFGEAEGALLHSTSSDGAAILRVLQALSSLVSSANEKQED
QVNVDGKDYNVAASLVREINSVLEPLWLELSSCINRIEVYSDAGIELPSSSLSVKSKPST
ASPPLPAGSQNVLPYIESFFVTCEKIDPAQPGTNQDIAVAAVPEVDDASTSASKQQASSP
VSKVDEKRAAFVKFTDKHRKLLNAFIRQNPGLLEKSFSLMIKVPRFIDFDNKRAHFRSKI
KHQHDHHHSPLRISVRRAYILEDSYNQLRMRSTQELKGRLTVHFQGEEGIDAGGLTREWY
QSLSRVIFDKGALLFTTVGNDSTFQPNPNSVYQTEHLSYFKFVGRVVGKALFDGQLLDVH
FTRSFYKHILGVKVTYHDIEAIDPDYYKNLKWMLEHDISDLLDLTFSIDADEEKLILYER
TQVTDYELIPGGRNIKVTEENKHQYVDLVAEHRLTTAIRPQINAFLEGFNELIARELISI
FNDKELELLISGLPDIDLEDMRANTDYSGYSPASPVIQWFWEVVQGFSKEDKARLLQFVT
GTSKVPLEGFSALQGISGSQKFQIHKAYGSQDHLPSAHTCFNQLDLPEYPSKDHLQERLL
LAIHEASEGFGFG
>Sgl11845 DUB/USP 210 0.0
MIVFGSFTEDEIRSLQGNQPEKSEVPVSKNKLQFGSLPCVPDDLLSAANGESGKKLASFV
KSPLQSAKKDVSTVTSKDVVPGSGKVLKENGSISGSELSRPLANGNKQINDGGPQLASPC
TTESVRTVVSQQLSSQPQDGQDIRSKERYSNGVHDGSVASLKIVPLNDLKKVSNGSIVTT
GDLLPRGLINAGNLCFLNATLQALLSCSPFLKLLQELRARDIPKVDYPTLIAFVDFVSEF
DIPLGLSSKMKDSNVVETGMPFSPAMFEGVVKNFTPDVPSGFSGRTRQEDAQEFLSFVMD
QMHDELLKLGGQGSGMALGKLSLVSSSEDDEWETVGPKNKSAVTRTQSFVPSELSAIFGG
QLRSVVKAKGNKASATVQPYLLLHLDIFADAVHTIEDALRLYCASETLEGYRASNTGKAG
VVRASKYVKIQTLPKIMIIHLMRFSYGSQGSTKLHKPVYFPLELVLNSSLLVTPINEGRK
YELVATITHHGRDPSKGHYTADARYSDEQWLRFDDASVTPVPTSKVLHDQAYVLFYKQV
>Sgl11883 E3_activity/RING/RING 34.6 7.4
MSNAAYGGRRASRRIAETNPVEGGASILTSKNGGGSNTEAMKLYEAIIFSGPIVFTLIIL
FLFYFFYLRRSVDWSSLRMRPTNSAAATADSDDLEVAELGLKKEFREMLPIIVYKESFSV
RDTRCSVCLGDYQAEEKLQQIPGCGHTFHRNCIDHWLATHTTCPLCRLSLVSPSKTPPTS
EPDSQESQDQADINNDGTENVDDVLQQNRVQVLSVHTEV
>Sgl11909 E3_adaptor/Cullin_RING/DCX/DWD 26.8 7.8
MAQFLFQNDELEFIDDIYQMTNFEDELLGFSDSSTPRTNRSNNDDDDDDSFDSDVDDDFD
FCEGQGKLKSDTTSMEARNGKDIQGIPWERLNFTRDRYRETRLKQYKNFESLPSSSRQQE
LAKLRNLLWATSKHDVYLMQNSSVMHWSALCKRSKEVLNVARPIVPTTKCLQSLPQPLSR
VQISTMCVKDNMLVAGGFQGELICKYINQQEVAFSTKVTTEENAITNAVDICNSSSGSKW
VIVGNNDAHVRVFDSANFVCFNQFRFPWSVNSTSVSPDGKLMAVLGDSTECLVSDSHTGK
VIGTLKGHSDYSFASAWHPDGQILATGNQDTTCRLWDIRNMSQSLEVLKGRMGSIRALKF
SSDGRFMAMAEPADFVHIFDTKSGYEKAQEIDLFGEIAGISFSPDTEALFVGVADRMYGS
VLEFNQRHCNGYLEAIF
>Sgl11969 E3_adaptor/Cullin_RING/SCF/F-box 15.8 0.0
MNEEEGNEIRQWDELIPDALGLIFKKLSLEDILTVIPRVCKSWGKAAQGPYCWQEIDIDE
WSTDCQRDKLDRMLRLLITRSSGSLRKLHVSCVNNDQIFSFIAENAGSLQSLMLRRSEIS
DSIVEQLAGKFSKVTSLDLSYCCRISTSGLEAIGKNCKLLSSLSWNMHPLASAYNKPSHV
DEAHAIAQTMPKLKQLEIAYLQINKESVYDILLGCPNLEFLDLRGCWNVHLDKKALEKRH
PKLAVLGPQVVMGAFEKQAFFDDYYSDSDFSDYGYMDYSDDESFDGMWDDEELEFRVYEG
ADYMYEFGWPPSP
>Sgl11985 E3_activity/RING/RING 22.2 8.9
MENVDSEEPEKKRPHLSSVSSPMARNSTLSPDSNSVDAALLQYQNQKLAQKIEVQKQEVH
DLEAKLQELKDRQSSYDDLLTNVKQVWNQTIDDLVLLGIKAGGGLDVLQTSDSEDCIQGS
TTSFRAEDFFLSRLLKVESMEGEGGESCFKFDEEFLEQHLFSFLKLLKCVEDFVEDQQRT
NNCVTQESKEILSVEGPGDAIKSNKFEDLMTECAKFLHILVDDLRQKHSDYVDRIQRYVQ
NQSEDDAEIKHITGDIEESVAEAEESRRKLGHLRMRKNLASGNYNPATAVNGTLSSYKVP
DRSMGLQELKDSIEEAEILAIDRLAELEDGREDNAIMLKQLQEIENEIKDDKYVSSSRLY
TLINDQLHHWKAEITRYKALTDTLQSERSYIIRREKELELKTESADHAKATAGNAETRVE
ELELKLRDSVIEKNELEGKMEEAVQDSGMTDIKTEFNVMASALTKEMGMVEAQLNRWKDI
AQEAFSLREEAESQKTLLNRKTSEVKSLGDKCAQQMAESKSLKELIEKLKKEKFELQIFV
DMLGQGCYDNRDLSEIEESERRACAQAEVLKHALDEHNLELRIKAANEAEAACQLRLSAA
EAEIADLRARLDMAERDVYELTEAIKIKDAEAEAYISEIETIGQAYEDMQTQNQHLLQQM
AERDDYNIKLVSESVKTKHAVNSLLSEKQTLGHQFQLINTALESLREHILRSEEQMKTTM
SEALSHCQEDRHLSVSLERAKWELSDLEKELKWVKSVMTSSEKEREQVQRKTVEIQRDLD
IDRHDRKKLEEELKEWKDKVAELTAETGEAAILKLQEEIKECKSILKCGVCFDRAKEVLI
VKCYHLFCNQCIQRNLEIRHRKCPGCGTAFGQNDVRFVKI
>Sgl12017 E3_adaptor/Cullin_RING/SCF/F-box 16.3 0.0
MEHNCIFPHDLVEDILSRLPVRDLLRLRCVCKEWCAVIDDASFIKKHYQVQYSICKVGSN
MPYFITEDREYKIKRTEEAYLLSIHQGDIITLNLTDDLERDSNGVFPNVTDQFYMQCCGC
VNGIICLSFINRIKTPFIDNCFLALWNPATREFKTVAYPNAPGLTYGHGFPILGFGFDLS
SNDFKIFGVFTDDRENDDELVFYHKLYSLNTNSWKTIPNPPPKALGLLPWAMNDGYFDGV
YYMTTDDRQYNCRPSYYEIVSFNFASEVFTVSDLPQEAISLVARSKIHQVMITLYKEKLG
LFVSHEVEEFGLCSIDIWVVTQLNDCGVPLSWQHLFTIEGTLDKLDMQVRSTLMNGDLLL
TYLIPTEDMPSFEDLIKTPTFYHSIYNQSRGDYKKFEIDLVAFFRYVESLFSISSMLV
>Sgl12033 E3_adaptor/Cullin_RING/SCF/F-box 14.4 0.0
MRKKNKNSWNNYFPLELEKEILARLPVKSLLQFRCVSKSWCSIIDSPDFKLHNNNNNSEN
PKFISIIEYRHNLSIALRRSDTFRKIGAEIANFDHWYVICQFCKGLVYISRLFTRKLWNP
SIKKCFNYSHCPVLGEEKLWVCFELGFAPSTLQRSEIKRVVFSGGAKYRVMFDDQSGGPV
ICVFDFDIEELSLVQPPDAVKGSMVWFIFRFGESIGVFTMSHERSCIWIMERNGGLSKTG
CNWRLWFTGEPNLDACSLFKSIEKEIFFVQKTCTFLMVKRTGSNPNLRRDRLMSYNLIKN
EIKHLAKSLRSYILFDTYVESLVLHKGIEGQTISSLP
>Sgl12037 E3_adaptor/Cullin_RING/DCX/DWD 37.5 9.5
MQGGSTGIGYGLKYQARCIADVKADTDHTSFIAGTLSLKEENEVHLIRLSNGGTELVCEG
LFSHPNEIWDLASCPFDQRIFSTVYFNGESYGAAIWQIPELYGQLNSPQLERIAALDSHS
GKIRSVLWWPTGRHDKLISIDEQNLLLWSLDSSKKTAQVHSQESAGMLHYLTGGAWDPHD
VNAVALYSESAIQLWDLRTMKMSSAIEQVHARSVDYDAKKSHILVTAEDESGIRIWDLRM
LKAPIAELPGHAHWTWTVKSNPEFDGLILSAGTDSSVSLWLASTSSSADATPESLVESPT
MCADPLLNTYSDYEESVYGLAWSSREPWIFASLSYDGRVVVESIKPHLSKK
>Sgl12070 ULD/UDP/UBQ/UBQ_PIM 51 0.2
MAEQQSAEGASTSDGSAAVADSMVEINIKTLDSRMEIADQIGVPVGQQRLIFRGKVLKDE
HLLSEYHVENGDTLHLVERQTTQPQTSTDSSGAIGGQGTDGGVGAPRNRIGQISHSVVLG
TLNVGDQGEGGTTDLNRVIGAVLNSLGVGNQTASAAFGAPSTAPANPSGLGPQGNDAERG
RGGNGSLNQAGNQAPFGQPFLSQAFQVPLAGVSIPSPPLSMPISDSLNTLSDFMSRMEGV
LSQNGYQPSSSPSGTADQPATELPLNARGLPTPEALSIVLRHAQRLLSGPAVAALSHIAG
RMEQEAGSTDASVRSQIQSESVQVGLAMQHLGALFLELGRTILMLRMGQSPAEAVVNAGH
AVYISSSGPNPIMVQVSSRIFQSVGFAVSHQTSPLFNTPAVSAANTGTSVPVGIIGSAPP
RHINIHIHAGTSLASMGSAVGARAAGGESAQGQSTGVASSAIAVSPVPNMSQPIGVVSTS
QPPDAASLSSVISQVNSRIRSFLENMNTDNQTPSVSGQQENPVVPSSSAGSGGGVR
>Sgl12087 E3_adaptor/Cullin_RING/SCF/F-box 16.8 0.0
MSINPELPEDIILIEILPRLAAKSLVKFKSVCRQWNTFISSVEFAKTHLHHPSFLSSTKR
SILTIGFSGDNRVFEAVDYYDADRNADSNNLYLTNFGKQFTALFKHLDLSASCNGLAFLI
ASPALKKYPLPYDYDDQSYEFSYVIYNPVLGVGDYVEIPHPRRFPLGSVEIGFIDMLISR
HYNFGFGYDSKSDDYYIVAVDLPGDFEIVFYVYSLRSHQWEPYITTLVVKDNGSPLFFES
CWQMHVGTLMKETLHWAMSLGHEKFILSYALATRNEAKTMNLPRPRFCNARECGGGIDFK
LCCLGDCLGAWANYKGCVADLWCVADLWMMKEYGVWESWTNLFRILLQDPVSCHNFFGFS
KSGMVLVFTNLHEIFLVDFTSDAPNISGPVLQKIKRGAVDYNPSLVSVLAIISGL
>Sgl12088 E3_adaptor/Cullin_RING/SCF/F-box 17.7 0.0
MNPNPELPEDIILAEILPRLPAKSLVRFKSVCRQWKTFISSVEFSKTHLHHPSFLSSTRR
SILTHGYSGDSTVFEAVDFYDADRNADSNNLYLTNLGKQFTALFKHLDLSASCNGLAFLI
ASPAIKKHRLLNDYDRSYEFGYVIYNPVLGVGDYVEIPHPRWFPLGSADKGFIDDYVISR
HYNFGFGYDSKSDDYYIVAVDLPGDFKIVFYVYSLRSHRWEPKITRLGVKNNVSPLSFES
IWKFHGGTLVKETLHWGMSLGHDYNFILAYSLATRNEAKKMYLPQPKFGNARECGGGCGI
DFSLCCLGGCLCAWANYNDSNEGIIADMWMMKEYGVRKSWTKLFRIKLDDTAGCEKIFGF
TKSGKVLVFTSSHETFLVDFTCDLLPNISGHVFENENWWPDWAVDYNPSLVSVLAIISGL
>Sgl12091 E3_adaptor/Cullin_RING/SCF/F-box 17 0.0
MNPDPELPEDIILNEILPRLPAKSLVRFKSVCRQWKTFISSVEFAKIHLHHPSFLSSTRR
SILTLGNSGGNRHLEAVDLEAVEYYDADPNADSNNLYLTNFGEKFRALFSFLELSASCNG
LAFLIIASPALKKRPLPNDYDQSYEFSYVIYNPVLGVGDYVEIPHPLRLSLGSVERAQRG
LLGMFFSRHLNFGFGYDSKSDDYYIVAVDLRHFPGDVKIVLYVYSLRSQHWETYVETLVV
KDNGSLLLFESIWKMEVGTLVKETLHWAMSQGYDNHFILAYDLATRNEVKKMNYPRPRLF
CNTRECGGGIDFKLCCLGDCLGAWANYRGLGYVADYLCVADLWMMKEYGVWESWTNLFRI
HLYDSVGCLNFFGFTKSGMVLVFTSRDQFFLVDFTSGLPNISGPVLENKRHGAVDYNPSL
VSVLAIVSGLG
>Sgl12141 E3_activity/RING/RING 37 4.7
MLLSIFLALFLPCAGMSVVFVVYICLLWYAASNAPPEPPVKPTVKKGLSAAELEKLPKVT
GNQLIHGNECAVCLDDIEDDQPARMVPGCNHGFHLYCADTWLSKQPVCPVCRTKLGPEFF
ESSTTQNPC
>Sgl12191 E3_activity/RING/RING 29.6 7.1
MSAESPSTPPSSPPPLPPVTAAAQHWCYHCDKRVSVESQSGQPDEVICSDCKFGFVESLP
PTNSSSSLLSPPPESVVFSDEPTLGDQFIQVLRLLAHVAREDEPPLHAPPPPPSSAPEDP
PPDESETDVFGFGITLDNWHRELEDHNNHININVDGGDDDDDAQEEEDDDDDDDEEVRSV
EIEGHTDEDEDEEEREEDIRRRRRDVLRLRLRDFANRARSEGRNRILDWAEILMGLEDNS
VEFRFELPESNDRYVGNPGDYVDAAEYEALLQNLADAEGRRGAPPASKTAVEGLKVVEIK
TVEESYACAICKDMVNVGECVKEMPCGHGYHGDCIVPWLAARNSCPVCRFELPTDDADYE
EERKKKKFPGSSSGSSGGTSV
>Sgl12194 E3_adaptor/Cullin_RING/SCF/F-box 15.3 0.0
MNPNPELPEHIILNEILPRIPATSLVKFKSVCRQWKTFISSAEFVKTHFDHPSYLSSTRS
ILTLGFDDERRLTLFEAVDYYHADSNNNLDLTNFGAHFKALFQYLSGSCNGLAFLIASPK
REKYEFSNDDDYDDSYEFSYVVYNPVLGVGDYVEIPHPRRFPLGDGVRGYFGRIYSRYYS
FGFGYDSKSDDYYIVAIDLPGNFKIVVYVYSLRSHQWEDYIGTLVVKHNDYDLPLIFECM
WYCHIGTLVKETLHWGMSQGHDNKFILAYALATRNQAKKMHLPRPRFGNARQGGGATDFN
LCCLDDCLCAWANYEGSVADMWMMKEYGVWESWTNLFCIQLDHPVHCRNFFGFTRSGMVL
LFTNLDEFYLVDFTYDPPNIFGPVLENEKRSAVNYSPSLISVLAIISGPG
>Sgl12232 E3_adaptor/Cullin_RING/SCF/F-box 14.1 0.0
MRKKNKNSWNNYFPLELEKEILARLPVKSLLQFRCVSKSWCSIIDSPDFKLHDNNNNSEN
PKFISIIEYRHNLSIALRRSDTFRKIGAEIANFDHWYVICQFCKGLVYISRLFTRKLWNP
SIKKCLTIPNCPVLGEEKLWVCYELGFAPSSNDYKVLAIDWVGYIGVYSVNDHRWRVKNI
QLPRLSALQRSEIKRVVFSGGAKYRVMFDDQSGGPVICVFDFDIEELSLVQPPDAVKGSM
VWFIFRFGESIGVFTMSHERSCIWIMEENGGLSKTGCNWRLWFTGEPNLDACSLFKSIEK
EIFFVEKTCTFLMVKRTGSNPNLRRDRLMSYNLIKNEIKHLAKSLRSYTRIFFDTYVESL
VLHKGIEGQTISSLP
>Sgl12239 E3_adaptor/Cullin_RING/DCX/DWD 31.4 8.8
MQGGSTGIGYGLKYQARCIADVKADTDHTSFIAGTLSLKEENEVHLIRLSNGGTELVCEG
LFSHPNEIWDLASCPFDQRIFSTVYFNGESYGAAIWQIPELYGQLNSPQLERIAALDSHS
GKIRSTVAAFYGSAMVCNFAMSETERGIGLTFAQIFVACTGLTSEIVLWWPTGRHDKLIS
IDEQNLLLWSLDSSKKTAQVHSQESAGMLHYLTGGAWDPHDVNAVALYSESAIQLWDLRT
MKMSSAIEQVHARSVDYDAKKSHILVTAEDESGIRIWDLRMLKAPIAELPGHAHWTWTVK
SNPEFDGLILSAGTDSSVSLWLASTSSSADATPESLVESPTMCADPLLNTYSDYEESVYG
LAWSSREPWIFASLSYDGRVVVESIKPHLSKK
>Sgl12266 ULD/UDP/UBQ/UBQ_PIM 67.9 0.2
MAEQQSAEGATTSDGSAAVADSMVEINIKTLDSRMYNFRVEKNIPVSLFKGKIADQIGVP
VGQQRLIFRGKVLKDEHLLSEYHVENGDTLHLVERQTTQPQTSTDSSGAIGGQGTDGGVG
APRNRIGQISHSVVLGTLNVGDQGEGGTTDLNRVIGAVLNSLGVGNQTASAAFGAPSTAP
ANPSGLGPQGNDAERGRGGNGSLNQAGNQAPFGQPFLSQAFQVPLAGVSIPSPPLSMPIS
DSLNTLSDFMSRMEGVLSQNGYQPSSSPSGTADQPATELPLNARGLPTPEALSIVLRHAQ
RLLSGPAVAALSHIAGRMEQEAGSTDASVRSQIQSESVQVGLAMQHLGALFLELGRTILM
LRMGQSPAEAVVNAGHAVYISSSGPNPIMVQPFPHQTSPLFNTPAVSAANTGTSVPVGII
GSAPPRHINIHIHAGTSLASMGSAVGARAAGGESAQGQSTGVASSGETGVTPVFPGRNVI
ATAAPSRTAAIAVSPVPNMSQPIGVVSTSQPPDAASLSSVISQVNSRIRSFLENMNTDNQ
TPSVSGQQENPVVPSSSAGSGGGNFDATNVSKSMHAESSGEANESLKDSVPGQQTQEDAT
EMRDNTQSDLLKSTEESGSLAVSTSRGGSGELADKATGAREIPLGLGGGLQPKRRNRQSQ
MQPGNGEGGSSSSPDQSQQARISGQQILQSLASRSTAARSSTDSGSGQAEQGQGQSMEGT
QASLDTDGQLDVTGTMSQLLQSPALDGLLSGVAQQTGVGSPDVLRNMLQQFTQNPAMRNT
VNQLAQQVDRDEFRNMFTGTGTGEDGSIDFSSMFQQMMPVVSQFLGGGSAQNEQLQNMMP
QLLPQIDRGSLEDNSFGQAFQEVVQMIANHSPSQDIFQAMVQNAALSTGVAEGELTDGLC
SNQDLVDGFVEMLRRDLLHRLQENSASGGNS
>Sgl12280 E3_adaptor/Cullin_RING/SCF/F-box 14.1 0.0
MRKKNKNSWNNYFPLELEKEILARLPVKSLLQFRCVSKSWCSIIDSPDFKLHDNNNNSEN
PKFISIIEYRHDNYSIALRRSDTFRKIGAEIANFDHWYVICQFCKGLVYISRLFTRKLWN
PSIKKCLTIPNCPVLGEEKLWVCYELGFAPSSNDYKVLAIDWVGYIGVYSVNDHRWRVKN
IQLPRLSALQRSEIKRVVFSGGAKYRVMFDDQSGGPVICVFDFDIEELSLVQPPDAVKGS
MVWFIFRFGESIGVFTMSHERSCIWIMEENGGLSKTGCNWRLWFTGEPNLDACSLFKSIE
KEIFFVEKTCTFLMVKRTGSNPNLRRDRLMSYNLIKNEIKHLAKSLRSYTRIFFDTYVES
LVLHKGIEGQTISSLP
>Sgl12284 E3_adaptor/Cullin_RING/SCF/F-box 17.6 0.0
MNPNPELPEDIILAEILPRLPAKSLVRFKSVCRQWKTFISSVEFSKTHLHHPSFLSSTRR
SILTHGYSGDSRVFEAVDFYDADRNADSNNLYLTNLGKQFTALFKHLDLSASCNGLAFLI
ASPAIKKHRLLNDYDRSYEFSYVIYNPVLGVGDYVEIPHPRWFPLGSADKGFIDDYVISG
HYNFGFGYDSKSDDYYIVAVDLPGDFKIVFYVYSLRSHQWEPYITTLVVKDNGSPLFFES
GWKMHGGTLVKETLHWGMSLGHDYNFILAYSLATRNEAKKMYLPQPKFGNAREFGGGCGI
DFSLCCLGGCLCAWANYNDSNEGIIADMWMMKEYGVRKSWTKLFRIKLDDTAGCEKFFGF
TKSGKVLVFTSSHDTFLVDFTCDLLPNISGHVFENENWWPDWAVDYNPSLVSVLAIISGL
>Sgl12345 E3_adaptor/Cullin_RING/BCR/BTB 63.8 1.3
MLEKKQQKFLTVAPFECAWQKEFKFKEAGRGCVVFEAFARNDVTVVFRENVGSQHYHYKT
DSSPHYTVVFGSHRNRRLKIEVDGKAVVDVEGVGLCSSAAFQSYWISVYDGLICIGNGRY
PFQNVVFQWLDSNPNCNVQYVGLSSWDKHVGYRNVNVLPLTQNHISLWKQLDSRVYNEDE
EDEGGYEEPMSNDKWGLVNFLESWELSDVLFIVGVEERSVPAHKVILAAAGNFKFAPGED
IIQLQEVGYPILHAFLQYIYAGQSKILESQLGPLREIGVQFEVMPLVKQCEEIIERFKTN
KKLFDSGKNVEIFYPNCQSLRPTVFPYGLPINVSRLQQFYSTGEYSDLEVYVEDFGFVAA
AHKVVISLWSVPFLKMFTNGMRESSSTKVYLKEISSEAMKAMLDYMYHGELMLEDIEENN
TLLLHVLLLADQFGITHLQQECCKILLECLYEGWRLSNGSRSYIKRDSVCQVLQVISSVP
SCKVIEESCKRKMSMQFDYCTSASLDFTLLDEAIFRSILQHPDVTVTSEERVLNAIFLWS
LQAKELHGWEAVDAFLIHSAPEVLFGQRLDSLNRLLPLVRFPLMPYDLLEKLEKSSIMKS
VPAFANLVKEAINYAKFGVTWTEVEPNPRFHHRRSSYKELQYICDGDSNGVLYYAGTSYG
EHRWVNPVLSKRITITASSPLSRFTDPKVLASRTYQGTSFTGPRVEDGRICSWWMVDIGE
DHQLMCNYYTLRQDGSRTFIRHWNLQGSLDGKHWTDLREHKNDQKICKPGQFASWPVTGP
QALLPFRFFRVISTVQTEPLKFCICFLELYGYFR
>Sgl12349 E3_activity/RING/U-box 118.4 0.2
MLTTKFRKSSSNLSLNCPIPYVTGDTKNGSPEGIIMVEDDNFSLITPKEGKDIIHDLEVL
IESIELIGEYRITQKKECQNLVRRIKILHLLLEEIKEVNANPPPNSAHATFCNLRKALLC
AKKLLKTCAEGSKIYVAVEREKFTSMFQLVNSKISQAMDDIPYDDLNISDEVKEQTELMG
QQLKRTKRRTDTQDLELAMDLMVVFSKEDERNADIAIIERLAKKLDLRTNEELKEETKAI
KRLENDKRVEEQLEIIMDVLHKFKQSAGIVEDNNLMLEDDADQIIMNNPEEQQQQIIRSP
SNKDIPQEFLCPITLEIMTDPVIVATGQTYERESIQKWLDSNHKTCPKTGQVLEHLSLAP
NYALKNLILQWCEKNKIQVPRKKITTTKTSLHPLSIMVTMRYHQQQQQQH
>Sgl12356 E3_adaptor/Cullin_RING/SCF/F-box 14.9 0.0
MKKKKNQISWNNYLPSELESEILARLPVKTLLRFRCVSKSWCSLIDSPDFNSLHFNLYNN
NNNNSENSKFIAIHEFRYNYSITLRRSDTFRKIGAEIANFDHPFSIRQFYKGLLLIRHNL
MMKLWNPSIGKCLIIPDCPVSELDFHMYYTLGFAAYSNDYKVVAINSKLGYTAVYSVNDH
CWRVKSIHRRGLPLSRLGYMNWVVVSGGVLYWRLYDDQSKSPVICVYDLDIEEFRLVQPP
GAVKGSMVWFIFRFGESLALFIMSDERSCIWVMEKNDGSDEDCNWIVWFTGEPNPDACSL
FKLIETEILFVQKTNTFVLVQKIPATVRHRVMSYNIISHEIKHLAKSLNREISFSTYMES
LALHKAIEGQTLSSFP
>Sgl12373 E3_activity/RING/RING 30.6 7.2
MSSLLVQIPCHHNYSNMADESNKILRVKFLSNNGCTLEVNPFCSDCKSDIVNEETRNVQY
QCPVYYNLMHRLLEQQVSSKITHQLESDDNNHNNNNNDDDEEFVFSAQDYRTEHLDNCGY
CLYFHLRSQVLDRWVELQRQSTQMYEESMAEVRIITPASEEAIDALERFSPATTSQQETT
TTTATTTTTCAICIDELITRDDDEVEDKVCARMPCKHEFHENCIIDWLHRSNSCPLCRFE
LPTNDDTMEF
>Sgl12374 E3_activity/RING/RING 37.1 5.2
MSSSLVYIPCNHDYQTVNMEARQKFLQVHFISDLRYVFEANPNCPSCKSDMLTATISRVQ
CPIYCLQLQRDFEHRVENKITELLLRDDDHSNTLHDDLFVYNALHYDIDHRCEFCSLVDT
IAEIFMENTMIDRVLVESLLDDGMTNITTLAPASNNAIDELERFNIIIPSQQEKATTTTT
ATCAICLDELIRNNNNKDDELGVRMPCKHEFHEDCILVWLRKSHSCPLCRFNLPAGTHYS
SRD
>Sgl12418 E3_activity/RING/RING 39.3 5.4
MRFRFLRSLNTSSSSSSSQSPPSDDGVDTVDSDFVVILAALLCALICVLGLVAVARCAWL
RRFSGGAASTPANKGLKKKVLKSLPKFSYSADQHAGKLSDDCAICLSEFISGEEIRVLPQ
CGHGFHLSCIDTWLGSHSSCPSCRQILAVRCHKCGGGLPENSNTSSSSTSAAAATATTTS
DEHHIHNHIHSSNNNTNQNRIGNDNANALPFLP
>Sgl12430 E3_adaptor/Cullin_RING/SCF/F-box 20.1 0.1
MFADTNIVEDGLRRDFESLSVSKKLVRSVSQKLRKKRVHRSAGDEEETANGFSVRFMSLY
GRGGGCKVGADTSEESGDSSTRRRSSASEEGKGYKPRCGAEETGVDCFSYGRKDRFWKRS
SRKDLEFEESQRNYRMNLSLPDDVLEMCLMRLPLSSLMNARLVCKKWNHLTSTPQFMQMR
RESLYQTPWLFVLGSVKDGYCSGEVHVLDVSLNRWLTIHAEVLRGRFMYSVASMRDEIFV
VGGCSSLTSFGRVDRSSFKTHKSMLVFSPSTKSWRKVSSMKYARSSPILGISEVSLDCPI
IHSQSNRQDRRFPRSRLGGVSDIYEDPHRLSVRRQLRSLSDDNAGFLAPIKKQCRPSRHR
SETSSLRDCKRFVLIAIGGLGSWDEPLDSGELYDSISNRWIEIQKLPLDFGIVCSGVVCS
GTFIVYSESDKLAGYDIERGYWTLIQTTPSPPRVHEYYPKLVSCNNRLFMLSVSWCEGDG
QIGRRNKAIRKMWELDLTYLAWTEVSIHPDAPMDWNAAFVADKNLIFGVEMFKIFGQVLD
FFTVCDVSDKVMKWSHISRNRVAQELDASSCVTKTIVAVHL
>Sgl12431 E3_activity/RING/U-box 84.1 0.1
MAGSSGGSTDLDSQSDDSSQVEKLHVEPIFSPFVCPLTKKVMRDPVAIENGNTFEREAIE
KWFRECKESGRKPTCPLTDENLKSTALNPSIALRNTIEEWTARNEAAQLDMTRRSLSTGT
SERDILQALRYVEYISEGSRSNKGAVHNPEILDLILRMLRNNSRKVRCKALETLRVITEQ
DSDLKEIMGEGDTVRIIVKFLSSDKFSEKEKEEAISLLYELSKSPNLSEKICSINGAVLI
LIGMISSNSANVLVVDKADKTLDNLSQSENNVRLMAESGRLQPLLRLILEGNLVTKLSMA
SFLGDLGLNNEVKLHVAKTVGSSLVNLMRNDDIQSREASLKALNQISSYDASAKVLIQAG
ILPPLVNDLFGVGGKQLPMRLKEVSATILSHVVNSGYDIDSVIIGPGNQTLVSEDIIHNL
LRLISNTGPSIECKLLQVLVGLTSSKTVHNVVSAIKSSGATISLVQFIEERDLRLAAVKL
LHNLSRYIAQELADALLAAGQLGALIRIISENNGITEEQAEAVGLLAELPKSDLALTHEM
LKEDAFRLIISRIKRIRQGEARGGRFMNPFLEGLVNSLARLTYVLAEDHEILAFCRDQNL
GSLFIDLLQVNGIDNVQIASARALKNLSSNSKNLTRKPEIPPPSYIESLFACFSKPPEIL
GLCPVHRGRCSVTETFCLVEGQAIEKLISLLDHTNENVVEASLAALSTLLDDGVDIEEGV
VILYKADGTKPILDVLVEKRTEDLRNRAVWVAERLLRVEKIAYEISNDQNVGTALVDAFQ
HGDYRTRQIAERALKHVDRIPNFSGIFPNNG
>Sgl12492 E3_adaptor/Cullin_RING/DCX/DWD 173.8 21.6
MVSITSTEINYLIFRYLHESGFTHSAFAFGYEAGINNSKIDGNLVPPGALVRFVQKGLQY
MELESNFSCSDADKDDDFSLLQPLDLITKDIDELQKIIKEKKESLCDHKHKEKEKEKEKD
HESENVRDRDKVKEKQTKEKAEQEKMRAQKDKEESKRKEKEKPQHNQVDVKPEDKSGIQN
EVNETPGAEPMDISMDTASLPLEIPSSDVKVLEGHTSEVFACAWSPAGSLLASGSGDSTA
RIWEIADGPSTSSMQNGLRNVVVLKHLKGRTNEKSKDVTTLDWNWDGTLLATGSYDGQAR
IWSKDGDLKSTLNKHKGPVFSLKWNKKGDYLLSGSVDKTAIVWDVKTGEWKQQFEFHTAP
TLDVDWRNNASFATCSTDNMIYVCNVGENRPVKSFSGHQGEVNAIKWDPAGALLASCSDD
CTAKVWSMKQDMYVHDLRGHEKEIYTIKWSPTGPGSSNPNQKPTLASASFDSTIKLWDVE
LGSLLCSLNGHRDPVYAVAFSPDGEYLASGSLDKCVNIWSVKEGKIVKTYTGNGGVFEVC
WNKEGDKIAACFANNVVCVLDVRM
>Sgl12493 E3_adaptor/Cullin_RING/DCX/DWD 158.8 20.1
MVLRLGTQELRNRGAEAVDISKDIASLHLKIPSSDVKILEGHKSEVCMCAWSPAGSLLAS
GSGDSTARIWDIADGPSTSSVNNGLLKVVVLKHLESRTKRNDVTALDWNLDGTLLATGSF
DGHASLWSKDGSLKSTLDKHQGPIFSLKWNKVGSYLLSGSVDKTAIVWDIRTREWKQRFE
FHTGPILDVDWRNSVSFATCSIDSMIYVCNIGEKRPLKSFCGHQGDVNAIKWDPNGTLLA
SCSDDCTAKVWSMKQNKYLHNLRGHEKEVYAIKWSPTGPGSSNPNKKLILASASFDSTIK
LWNAKSGGAVYTVAFSHDGEYLANGSSDNCVNIWSVKDGQLVKTYTGKGCVFEVCWNREG
NKVAACFANNVVCVLDIRM
>Sgl12513 E3_adaptor/Cullin_RING/SCF/F-box 11.8 0.0
MDKSIEMDSLIWSNLPEELLDRILCFLPFTTILNLRPTCKRFKSLLFSPFFLSNFYPSSS
SSSLVSSPFSCFLLLSHPHFNRHFPVYNSVSGVWRESSVSRSLLNPCSSSSSLLSSSNGL
LCFHLPRSSSFLVSNLLSRSSTLVKYPKLPFTFEFLNLVSYPNGFKIFIFSSKHVFLYDS
KHRSWKTFDGYEPILNDNIHHQGVYRDGRLYFTTSHPFSIVSFDLEKGIWGNFLDEMPFN
ELAFARLVMADNEGGNENKVYVIGGVGRNGISRCLKLWELAENLGSATESKSENAGKNTN
YSSWIEIESLPDLMYKKLVSVCYHNYEHIYCFWHNGLICICCYTWPEVLYYKVSRKTWHW
LPKCPSLPEKWSCGFRWFSFVPKLYASF
>Sgl12515 E3_adaptor/Cullin_RING/DCX/DWD 46.2 6.5
MADGVMAVEWSTSSEWILMTGGCDGAIRFWDIRRAGCFLVLDQSKSQLGRRPPLLERSVA
EKDGQGSSAMNRGQQRKPSSSNGTKLAVSSRMSSQLKGGYAKQRRHPGLMSSQDHATAHY
GAVTGLKATEDGMYLLSTGSDSRLRLWDIKSGCNTLVNFETVRLQNSKATQLAVAQDSSL
VFVPCMTSVKAFDLWSGETSLTCRAHFECVNCCWFSAQDQELYTGGNDRQILVWSSSKLS
PDDVDERSVKGNLLMKDEDNWSD
>Sgl12516 E3_adaptor/Cullin_RING/DCX/DWD 44.7 0.2
MFSREIARREEGTLHPNTFSRRIRSRRISSLHLSNSKELISPHRGAINSLQVDLTEGRYL
LSAASDASAAIFDVQRASEFDAEGHVSRHKSLFVIDKQHQQGHKYAISSATWYPIDTGLF
ITGSYDNHINVWDTNTTQVVMNFKMPGKVYKTAMSPVATSHMLIASGTEDVQVRLCDIAS
GAFAHTLSGHRGMLIN
>Sgl12536 E3_adaptor/Cullin_RING/DCX/DWD 53.1 18.0
MLQQHTISSIDWKPSPITALATSVDDSQVAAAREDGSLEIWLVSPGSIGWHCQLTIHGDA
NSRISSLVWCRTSLKGSSSGRLFSASIDGSVHEWDLYQLKQKTVLESVGVSIWQMALEPM
KIILESVENVPHSNGNGVVVDYNSESSDDDSDDSVELCEDSSLENRRLALACDDGCVRLY
TIPDANQLTYHKSLPRVSGRALSVAWSSDGNSIYSGSSDGFVRCWDAKRMQELYRITVGL
GGLGSGSDLCVWSLLVLRCGVLVSADSTGSVQFWDSKHGTLLQAHSLHKGDAYALAAAPS
HNKVFSGGSDGKVILYKLSVDAADSSLNNMKSSEVRKRWVYVDSRSAHTHDVRALTLAVP
ISQEDLLPDEKVKKVRRKLKPVEFSYHKWANMGVPMLLSAGDDTRMFAYSANEFTKFAPH
DVCPAPQRVPLHFVQNSVFNKMPLLLVQTTNGVDIMSLKLKNGAILDKAPGGQASTSLLA
RVNNKGSGKITCSTISPSGSLFCFSNHVKPRLFELKRGEGSKTAWVIDKRQLPGKVPYAH
AMTFTSDSSRLIVAGSDRRIYIVDVESIAVLHVFTPCRKTQDEFSPPSEPPITKLFTSSD
GQWLAAVNCFGDIYVFNMEIQRQHWFLSRLDGASVTAGGFSPQSNNVFIITTSSNQVYAF
DVEAKQLGEWSRKNTPALPRRFQEFPGEVIGLSFPPSASSSTVVVYSSRAMCTIDFGLPV
EHDDSSDMVTTDMLNGLDSVSKKLLNSNGRLKRKLQQPDMYIKLYGRKNFEFCQFKHPVL
FVGHLSKSSLIVVDKPWLEVVKSFDSQPIHRHIYGT
>Sgl12549 E3_activity/RING/U-box 98.5 0.9
MPMYEPNKVEVSGGGQVIDLETAVKDGILGCGGVEEGGGGGFSYLSEKIELKKMVEELES
IEVPTVFICPISLEPMQDPVTLCTGQTYERSNIMKWLSLGRLTCPTTMQELWDESVTPNK
TLQQLIYTWFSQKYLVMKKKSEDVQGRVLEILENLKKVKGQTRVQALKLLKQIVGTHFSA
KKTMVDNGGVLFLSSLLGPFTSHAVGSEVVGILVNLGLGLEAKSNLTQPAKISLMVDMLN
EGSIETKINCTRLIQGLMEIKDFDPGLVSSLSLLVGLLKLVKDKRNSNGVQPGLSLLNMI
SSHECVRGSIISIGAIPQLVDVLPSLNAECLELALSVLDNLGSVEEGRLGLKDYPKTIPN
LVKLLMRTSEICTQLALSILWAVCKLCPEECAPIAVEAGLAAKLLLVIQSGCNPALKQQS
AELLKLCSLNYTATIFISKCKLTRTLQ
>Sgl12725 E3_adaptor/Cullin_RING/SCF/F-box 15 0.0
MAANGQGRNVSSKRPIKLNRFLTIDEHIIGEILKKLPAKDFAFAACVCRSWKRVSDETLS
ISKLVTGVSLKPKPLDAIKEAMQEVLSKPIRPQFVIANFTMGYNLPIVHDYMKRKFGRSI
PIITNSVKGVIGQHVKSQELIEVTKKEVSNEYMDDYSSSDDSILPIFGLVLIVGWFPDMK
IDAIPLISSTRAQGTNEAENTRLVTRIDEEFTNETAIVGHFSKYIDFRASSQRPQFRRSR
YRSLDVVALVFAKDRFKAPEIGNTQFHVPCMKSVSQIGSTYNVASINQIDLRKNITYFNG
RRDSNGELLNGSSLCSLDGMDERIYMDDYYIGIEKKSAPKIINKDDASTSATPQMSSTSI
SLYSLQLDEDDGLESLVVKGKDIKVGDSFEFYRADFERSLTMEGVVKPPNVQAHHPDAKV
IGGLIFANMCETVEWMTRDPLAYSTPFIDQFGEDIPLGGLFTKHIVKRGSILSAWKDVEE
QQIGDCSTGPKATQFLVMSFTPPIPAPPPIIIED
>Sgl12782 ULD/UDP/UBQ/UBQ_PIM 82.9 0.3
MKVFVKSLKGNHFQIEVQPQHTVSDVKKNIESVQGANVFPASQQMLIYQGRALSDGTTLE
ENKVTENSFIVVMLCKSKNSSRESSVAAAAIPTPKTKSLSGEGATVAVAVAATPTYKNTG
ESSVAAAAVPTSKSESSPKGSSVAESSMPTSKSKSSHGKGPVGEPTMPIVKSKVVQWKQP
LCTSMAPATRESPSVKASSAPPTPVTNASVPASMPIPVSVPVNASISETDVNYQTASNFG
AGNGLESTIQHILDMGGGIWDRSTVERALHAASNDPDKAVEFLYAGVPEQAEAGKPMDPS
AASQQPTRSTTIPPSISNADPLNSFPRGLSNLESDASPLDFLRHSEQFQALRAMVQANPQ
TMQPVIQEFGKQNPNLMRLIQEYQADFQRLLNEPVQGEEGNILEQFASAVPQAVQVTPKE
HASIERLEAMGFDRSTVLEAYFACNKNEELTANYLLDHMHEF
>Sgl12846 E3_activity/RING/RING 28.3 5.8
MAEVSFLQFPEEDHDLFAENDLLIEEITTLNSIHCWSNIPTSDCFSSHQHAIDDVEDEFF
ATNLVSNPSIGSDSTDNTILLEDRKNQVNFVMDLFQQRVEQSNYVGRNEIVLESGNDLSF
GVIEENIDVGVDDLDLELRLGLGLGLELDEEAKDDEEDSNCGGFVVTDCGDEFYIARREN
GSEIVSNDNEINPISSSRVGGLMFVGIDSGSEAADEGGNDGSFRFHVHSDEEEYGVDYDN
YDDYDVDDDNVSIPLCWDSFQLDEVEDHNRGYGNDFEWEEVDDRVVDAEAMSSSELGLII
SGPDENGVGERERGEFGHLSWEVLLDVNNMGRNSEMIENVIDIDDQEHDIFNAAEYEFMF
GQFAESENAFLGRPPASKSVVEKLPTVITTDEDVLNEKALCAVCKDQIEVGNEGKLLPCS
HRYHGDCIIPWLGIRNTCPVCRYELPTDDPDYEQRRVRRLARGA
>Sgl12847 E3_adaptor/Cullin_RING/DCX/DWD 69.4 9.9
MKAKAVKLREAHKSCINGKPSFCSVLWDNKSTNIVTSSSSDSSISIYESLLLSTPMKNLR
HHRDGVTALALSPNSTCLASGSIDRTVKLYKFPSGEFQNNITRFTLSIRALAFNNSGSLL
AAAGDDEGIKLINTVDATIARVLKGHKGPITSLAFDPLNEYLASLDTKGTVIYWELQSGN
LLHTLKGVAPDTSHDMSIMNVISWTPDGDFLSVPGLKNDVIMYDRDTAELQYYIRGDHVK
PISALSWSPNGRYLATSDSDNQVLIWDVDKRLDIDRQQFDERICSMAWKPTGNALAIIDV
MGKYGVWESVIPSSMKSPTEDVLQSKYSNGLLLFDEEEQEQSISASFSDMGEDNFVESVP
HTKKRLRKSSLYEESLEEDIISEELDSHPRIKSHRKPAKNHKECLDGGDGKPKSMSVQNF
SKLQEPFQPGATPVQPGTKCFLCYNMLGSITIMQHDGNSHIEIDFHDTSQGPRVPAMTDY
FGFTMASLNENGSVLANPRNGEKNSTLMYRPFSSWANNSEWSMRFEHEEVKAVALGTGWV
AAVTSAQLLRIFTEGGLQRHVISLDGPVVTAAGFKDELAVVIHTSQPLPSNDQMLEFRVY
NIGNGTQPRKGRLPLSPGSCLTWFGFSEEGQLASYDSKGELRVYSDQFGGSWLPLFSASK
VKKPDENHWVVGLNAETLFCIVCKSPDLYPKVSSKPVLSLLDLSFPLASSDLGADTLENE
FIYRNTRLLQIQKTIDEREAAGIDCTMLDDEAFNMETALDRCILRLIASCCNGDKLVRAT
ELVKLLSLEKSVRGAIKLVTTLKLPNLAERFNSILEERLLNDAAKNVPLSHSNSHVDTGT
RTNITKSYTSPNTFTEKSINSNNTFSNNFSPNLSNEPSEPITPSPTPKFTAHVFPKKAKI
QDGSSFRPVNIEQNKSSALNNAPKSIDITKAAVNESLVKQGNAAEPTKKARFPGASNPFA
KPTNDTDTRPKNPFAKSSNAQDKSSLLDSIKKMKTLS
>Sgl12850 E3_activity/RING/RING 24.3 6.5
METLDPNSISNPNFNLESPSKRLKTETLTLDSSIEKGKAPIIVEDVEESEDDGEESPTPE
NCGICLSEEGKTVRGLIDSCDHYFCFLCIIEWSKIESRCPLCRGRFSSIRRMRKDGSFIG
NSSVRVPVRDQFYDPFGEPADPYLQAKCSVCNGTSDECLLLLCDLCDVASHTFCVGLGAT
VPEGDWYCRDCTLLRAEQCESEMGDDAVTSTHVDESSLASVSIFDIVRNTNDSGVHNSGT
DRLLRFVTTNFSSSAAASDRSNIASARSVPVTRGNLHPSVAASESSARTLRNCRNVHKHI
NVLRENWDSFRAGSLSFSHASSKSSAKLNEKKIAAGTSAQKSGTLQSCSSSSSSQSKAVD
SVCQATQDKEPYNVNKAWKLMTIAKKVQLIDKSMSASKVAQNKAHSVKKDKSVTHKCVAS
GRKDLMPSKLEKQKLGDKASESLAPSSGKHHSTSFGASVLGSKHQKFCANKLSIPRVIQT
TSKPNGYPDRLGLSSSSKYPKGTCSTVLDASSSLSSSSFGPIAEASDVPFASLQRDISAH
PVKKVMHLNISSSSKGELETSLQAGIGHEAYNKNGLSSTDLGRGLSNNSDKISGFACSTS
SFERVVGGSDTSHVNLKGKMRSAYPEEVGKITSKSSKDDEAKSEIQSLVKLNLKLIGKDK
RLGVDDFKEIARVSTHTILASCGFEHRKIVRSLHTLVCPHADQTQPLSRSTIMPNSCREC
FYVFVKNVVNSIMFEKLNSAEVAC
>Sgl12875 E3_activity/RING/RING 22.2 0.1
MDSGNKVFTVDLLERHAAKGHGVVTCMAAGNDVTMWGTSKGWIIRHDFGIGDSYGIDLSG
GRTGDQSIHKVFVDQGGSHCIATMVGDGGPETFYIHAKWNKPRVLSKLKGLVVNAVAWNR
QHITEASTKEIILGTDNGQLHEMAVDEKDKREKYIKLLYELTELPEAFMGLQMETASIST
GTRYYVMAVTPRRLYSFTGIGSLESVFVSYHDRAVRFMELPGENVNSELHFFIKQKRAVH
FAWLSGAGIYHGDLNFGASHSSQDGDENFVENKALLDYPKLFDGAEVVKPSSLAISEFHF
LLLVGNKVKVVNRISEQIVEELHFDLSSESSSKGILGLCSDASAGLFYAYDQNSIFQVSV
NDEGRDMWKVYLDMKEYAAALANSRDALQRDQVYLAQAEAAVSTKDFLRAASFFAKINYI
LSFEEITLKFITANEQDALRVFLLWKLDSLSKDDKCQITMITTWTTELYLDKINRLLLED
NSTSADHNSEYRSLINEFRAFLSDSKDVLDEATTLKLLESYGRVDELVFFASLKGQYEIV
IHHYIQQGEVKKALEVLEKPRVSAHLLYKFASDLIMLDAYETIESWITKKDLNPRKLIPA
MLRYSSEPLAKNETHQVIRYLEHCVHGLNNEDPGIHNLLLSLYAKQEDESALLRFLQSKF
SNARQNWPEIFYDPKYALRLCLKEKKMCACVHIYSMMSMHEEAVALALLVDPDLAMAEAD
KVEDDEELRKKLWLMIAKHVVGQEKGTKRENIRKAIAFLKETDGLLKIEDILPFFPNFAL
IDDFREAICSSLEDYNKQIEHLKEEMNDATRGADNIRNDIGALAQRYAIIEHEEECGVCL
RRILNTYAAFGISRGYASVGPMAPFYVFPCGHAFHAQCLITHITRCTDPENGRHILDLQK
QLTLMSSETRRDSDGSLANEPVASTNQVDKISSQLDEAIASECPFCGELMIKEISLPFIL
SEEEEVNSWDIKPPNQKNISLSV
>Sgl12979 E3_activity/RING/U-box 31.3 0.3
MAMERSTEESPDAHTYLMLQPKFKLNLWKTIFHGVPWLDIFFFFKKKKLKYCQNFKDMDL
IQNFQNFTAECRSEDDATVKQDCKSGLSPTTEPESSQGSFDCNICFDLAHEPVVTLCGHL
YCWACIFKWLHVQSSSSQSTPHKACPVCKANISQSSLIPLYCHSPPRAQDGSGKSHYDVI
PPRPTAVNSSSNRHLSPNPFESRYPEFHYGNYASISSLNHVSPTMAGIINPTIELLGELV
YTGRLGSTDAGSFAFPHPNSYAAVGNNSNPRMRRQELQL
>Sgl12989 E3_adaptor/Cullin_RING/SCF/F-box 16.7 0.0
MKHSKHEESHLAELPVEVIKKILLRLPLKSLGKCKLVSKLWHSLISNPEFATFHLQFSNH
IGNSPSILALDRNKLISIATPKIDSSMDMITDGAPCLITLDREFNPPRRGHDCVFLVGSC
HGLVCLYLKKIRKPEDLMYLWNPTIDKHKHIPLPIEQGLTYVYARPSWFGFISSLNTYKI
FLVYKVHKQEYKYVCSLRDLKWREIREVGGKVGIPDLWKFKSVVMNEALHFLIGRECILR
FDLVAETFEKIPLSIKPDVLPRSCRMLLGVLRENTCLCALVIHWPQEWIFDLWILEEYNK
WDSWKKMYKIDLETNIGNDFGFIESGYYCVEGEKELVLIDPSHNPPLFVNVEKNGKTLYK
LTYHVESLVSSLCLP
>Sgl13021 E3_adaptor/Cullin_RING/SCF/F-box 16.8 0.0
MKHSKHEESHLAELPVEVIKKILLRLPLKSLGKCKLVSKLWHSLISNPEFATVHLQFSNH
IGNSPSILALDRNKLILIATPKIDSSMDMITDGAPCLITLDREFNPPRRGHDCVFLVGSC
HGLVCLYLKKIRKPEDLMYLWNPTIDKHKHIPLPIEQGLTYVYDRPSWFGFISSLNTYKI
FLVYKVHKQEYKYVCSLRNLKWREIREVGGKVGIPDLWKFKSVVMNEALHFLIGRECILR
FDLVAETFEKIPLSIKPDVLPRSCRMLLGVLRENTCLCALVIHWPQEWIFDLWILEEYNK
WDSWKKMYKIDLETNIGNDFGFIESGYYCVEGEKELVLIDPSHNPPLFVNVEKNGKTLYK
LTYHVESLVSSLCLP
>Sgl13147 E3_activity/RING/U-box 29.6 0.1
MAIGYRQSMSSVPSPNASCSSNNGSSGGGDASTFECNICFDLAQDPVVTLCGHLYCWPCL
YKWLHFHSMARDCPTCKASVQEEKLVPLYGRGKNSMDPRSKSIPGMNIPNRPTGQRPETA
RPHENNQFNQHGFGFMGGGVGVGGWGGFPPVATARVGNFALSTSFGGLIPYLFNFRMQGF
PDTPAYGAGVGYHPYGYANAFQGQDPHVHHIRRIQRQQEHILRMLFVVIILFLLFTFLSA
NN
>Sgl13200 E3_adaptor/Cullin_RING/DCX/DWD 20.6 0.3
MMTSVYGVTYIGARDQIKKRLKERALFSDDAELYGAACYTAREMVVLVSTCNNDGKIRVF
KWPSMDVLVDENEAYIEVKDLHISIDGEHLVSVGNGGPCKIWDVASSKVVASLQKENDEN
FRFCRFSQSSERDQVLYTLTTRGKGVSIISWNTKSWNIIAAKHITRDPVSAFNVSIDGKL
LAIGTVEGGILIINSSKMQVQMTVKTAHMGLTGTQVGIVNFEFLSYKLLPIVGKSSWFLH
CFALSCWFALSCLCEQLEFSVRVPELFLLRDLSFNSITGSIPDSVFSLSSLSHLFLGNNR
LTGALPAQKSSSLTTIDVSYNRLSGNFPSWISQRNLQVNLVANNFSVSSSNSRSLPSGLN
CLQNEFPCNSGAGRYSDFATNCGGPQIRASNQIVYESDNEALGPANYLVRSSDKWAVSNV
GLPASSNNVTYTYNSQRQFVSLDSELFQTVRMSAGSLRYYGLGLQNGNYSVLLRFAEIQI
ESSTQRTWRSLGRRVFDIYIQGNRVEKDFDIRKEAGGQSYRPIQRNYTARVMANFLEIHL
FWAGKGTCCIPVQGAYGPSISALSVTPLFEPRAIASTTSHTAAIVVGIVVPIVVIALLSL
GACWFIQRRKKLRAAEEELLGIDAKAYSYAELKSATKDFDSSNKLGEGGFGSVHKGTLSD
GRVVAIKQLSITSNQGKSQFIAEIATISAVQHRNLVKLYGCCIDGKKRLLVYEYLENKSL
DKVLFGDNKLEFNWDKRFEVCLGVARGLTYLHQESRLRIVHRDVKSSNILLDSDLNPKIS
DFGLAKLYDDKKTHMSTGVAGTVGYLAPEYAMRGHLTEKVDVFAFGVVALEIVSGRANHV
PSLGKEEMYLLDWAWHMYENGLDTELVDKRLKAYNKGEVKRVIEIAFLCTQTSPGQRPTM
SRVLAMLTGDVEVGTIPSKPTYLTDWAFDDDTSFMTSEASDYSKTGYSSTSNYTSSQGPN
SHADNVSLVVK
>Sgl13206 E3_adaptor/Cullin_RING/DCX/DWD 20 0.2
MMTSVYGVTYIGARDQIKKRLKERALFSDDAELYGAACYTARDGKIRVFKWPSMDVLVDE
NEAYIEVKDLHISIDGEHLVSVGNGGPCKIWDVASSKVVASLQKENDENFRFCRFSQSSE
RDQVLYTLTTRGKVVSIISWNTKSWNIIAAKHITRDPVSAFNVSIDGKLLAIGTIEGGIL
IINSSKMQVQMTVKTAHMGLLWRWGANEQCSKALFNWFVERIFESSFVGRRSIIKERFSK
KYRHPTLDAKLTLKCLIYEITQDYKVNFYFLIIFNSYSLFNLLK
>Sgl13219 UBD/UBC-like/UBD_UBC 91.8 0.0
MVFLRASRARLFKEYKEVQREKTADPDIQLACDDSNIFKWTALIKVSCISRNFELPYYLS
WSYLGIPYLQGPSETPYEGGVFQLAFAVPEQYPLQPPQVRFLTKIVHPNVHFKVRALRLV
RFAWSHAWTLQSVCRAIIALMAHPEPDSPLNCDSGNLLRSRDLRGFQSMAKMYTRLAATP
KKG
>Sgl13480 E3_adaptor/Cullin_RING/SCF/F-box 21.2 0.0
MGGAFRFSAATMVKKGRNSVSVGWCSRGFSRLFWVFWTIFCSNFVLVAESWLLHQIAMAL
SLQRYTLHDSDPTTSFNRLLKERVTKEKERSMLIAIEKLEHLPDNLIVEILSWLPVKDLL
QFKTVCKSWYSIISSPDFASKHLQNYCYNNNDTWRGCLLVQFSVPYAEHEVYELLVDETP
RVLGDEVLAYMPKFNSYVCGPCDGIYYMFHCCRRERALWNPAINEFRPLPTIISRPDLPA
NLTYENYEVYGFGLDPVTRDYKVVVVKGYWNTSNEEESHLNLPISVLVYSLRTNSWKYCG
DLRRYYNLEVNTSYICVNGCCYWFGSHDFGDEVVISFDLANDTFKEMDVPDHAQPSSKCL
GMYDDFLAFMSLHESEKNFDLWTLKEGYWTKKLSVGPFPDVWRLLGHSMDKKLILQCHDG
SLGFLDPDTQQIKDLAFQQRRRCEGAFAYMESLVSIKDKNAEEVEA
>Sgl13602 E3_adaptor/Cullin_RING/DCX/DWD 14.5 1.5
MTTVKSFFAKVYPHSVAWCLEMIVVWKLIRQHGTLPITSAEQEPDVMRTLVDVHSQECLE
YEAEIVFKLAGHQGSIFFLSWSDDGSKLVSVSDDRRKSPNLYSAGPVLFGHGARVWDCCI
SESQRKKEKSYLNWGDIPAATAEDVELAVAAARRAFKRNKGADWASASGAHRAKYLRAIA
AKAVFAGTLVNLVTLLSLHSIRVRVHRAKVTGQEVIIKVQRPGLKDLFDIDLKNLRLSGA
PSQLVKKASKKRPARPAIPSSQKGKRPKSGELKEEKKEEQREELSDQAFA
>Sgl14206 E3_activity/RING/RING 20.7 4.8
MECLHRFCRECIDKSMRMGNNECPACRTHCASRRFLRDDQRFDQLIAVLYPDIRKFEEEL
MYELEDVDLQKICYEVPSKRKKKVLLICLHISIIRIVLNDYFFAQIQESITQVLIKLSEA
LGKKRSSNKDAAGPSVTRSQQ
>Sgl14343 E3_adaptor/Cullin_RING/DCX/DWD 29.9 1.5
MTKDEEDARREIVEKVRMWQRDARDRTTLQPTPGAAVDLLPPAAYSDNPSTSFAAKFVHT
SLNKNRCSINRVLWTPKGRRLITGSQSGEFTLWNGQSFNFEMILQAHEQAVRSMVWSHNE
NWMVTGDDGGSIKYWQNNMNNVKANKVAHKESIRDLSFCRTDLKFCS
>Sgl14574 E3_adaptor/Cullin_RING/SCF/F-box 17.9 0.0
MSMNPELPEDIILIEILPRVPAKSLVKFKSVCRQWNTFISSVEFAKTHLHLHLHLHHPSF
LSSTKRSILTLGFSGDNRVFEAVDYSDADLNADSNNLYLTNFGKQFTALFKHLDLSASCN
GLAFLIASPAIKKHRLVNDYDRSYEFSYVIYNPVLGVGDYVEIRPPRRFPLGSVERGFID
MLISRHYNFGFGYDSKSDDYYIVAVSLVKDNGSPLFFESGWKLHVGTLVKETLHWAMSLG
HEKLILSYALATRNEAKTMYLPRPRFCNAI
>Sgl14625 E3_adaptor/Cullin_RING/SCF/F-box 21.2 0.0
MREGGEDGRSTVGRSHGRRSEGLVWGFSRLFWVFWTIFCSNFVLVAESWLLHQIAMALSL
QRYTLHDSDPTTNFNRLLKERVTKEKERSMLIAIEKLEHLPDNLIVEILSWLPVKDLLQF
KTVCKSWYSIISSPDFASKHLQNYCYNNNDTWRGCLLVQFSVPYAEHEVYELLVDETPRV
LGDEVLAYMPKFNSYVCGPCDGIYYMFHCCRRERALWNPAINEFRPLPTIISRPDLPANL
TYENYEVYGFGLDPVTRDYKVVVVKGYWNTSNEEESHLNLPISVLVYSLRTNSWKYCGDL
RRYYNLEVNTSYICVNGCCYWFGSHDFGDEVVISFDLANDTFKEMDVPDHAQPSSKCLGM
YDDFLAFMSLHESEKNFDLWTLKEGYWTKKLSVGPFPDVWRLLGHSMDKKLILQCHDGSL
GFLDPDTQQIKDLAFQQRRRCEGAFAYMESLVSIKDKNAEEVEA
>Sgl14640 E3_activity/RING/RING 19.9 4.6
MDQENPSSASVVEISLSDSDFSSDEEISEVIPAPGNLNASKNRLPSRAGSGGSGFHMQPG
PSFREGHHPRVLPHTLVHGELGSSGDNTTTSDPYQTYQTVGFGEENVLGNERIIFQAALQ
DLSQPRAELDVPQGILSVSLLRHQKIALAWMVEKETRTMHCMGGILADDQGLGKTISTIA
LIIKQLLAQLKSQLEKHDNDFAEALNLDDDDDDSTGDKKEDPNAGKCKSAEVCNSEPMLY
NLADDDDTGSGSTETVKKMENVDGLKSDSSSRSSSSLPKVQGKRPSAGTLIVCPATVLRQ
WARELSEKVAKKANLSVLLHHGSFRTKDPKILARYDVVLTTYAIVSNEVPEQPIIDEDDG
EQKTVDRFGLSSDFSVSKKRKHASTNKNGKKGKKAGPLARVNWFRVVLDEARIIQNHRTQ
TARACCRLRAKRRWCLSGAPIQNSVDEIYSYFKFLQHDLYSRYENFYYGIKNPISRDPTI
GYRKLQAVLKTLLLRRTKETLLDGEPIICLPPKTIEMKTINFSVEERSFYAQLEAESRSQ
FKAYAAAGTVNQNYANILLMILRLRQACDHPLLVKGFSSGPARKTNLESARNHPRHLLMG
LLNHLDTASAICQICSDSAEDAVVTICGHVYCYQCVADYLNGGDTLCPALRCKEKLSDDV
MFSESTLKCCLYGDVDVDGKSVNDNGCSKTPSILSNEYSSSKIKAALEILLAHHELNRKI
LEHDEFGSTSAGNSISAQVRIEKTENSSSKGPLKTIIFSQWTRMLDLFEYHLNHYCIPYR
RLDGSMSLAARDRAVREFNTIPEFTCILMSLKAGNLGLNMVAACHVILLDPLWNPAAEDQ
ALDQAHRIGQTQPLTVSRITIKDTVEDRILALQKEKRKMVASALGENHDASFGARLTMDD
LKYLFLGSLGI
>Sgl15114 E3_adaptor/Cullin_RING/DCX/DWD 159.6 32.3
MAMACDASGGLLATAGADRKVIVWDIDGGFATHHFKGHKGVVTCIMFHLDHNRLLLFSGS
DDATVRVWDLVAKKCAATMEKHFSAVVSLAMSEDKIFLLSAGRDKVVNMWDLKSYGCKTT
VPTYEVLEAVCVVSPGTAFYDSLSSQKSKKSKSAGQDVYFLTVGERGIVRIWNSEGAVCV
LEQKSSDVAFSPDENDLRRGFTAARMLPSDQGLLCVTADQQFLFYSFIKHSEEDLELGLS
KRLIGYNEEIVDMKFLGDDENFLAVATNLEQLRVYDLASMSCSYVLAGHTGTILCLDTCV
TSSGVTLIVTGSKDNSVRLWNPETRRCVGVGVGHTGAVGAVVCSKKWRNFFVSGSSDHTI
KVWSFEGLDSDTEEPISLKAKAIVAAHDKDINSLAIAPFDSYVCSGSQDRTACIWKLPDL
VSVAKLKGHKRGIWSVEFSPVDKCVLTASGDKTIKMWALDGSCLKTFEGHTSSVLRAFFI
TRGTQFVSSGADGLLKLWTVTSNECIATYDEHEDKVWALAIGKKTEVLATGGGDAVINVW
NDSTAADKEEAFRKEEEEVLRGQELANAVSDADYAQAIQIAFELRKPHKLYELLSELCRK
KDAVDHLRKAVMPLGKEEIQQLIEYIREWNTKPRLCHIAQFVLFQVFSMLSPTELVEVKG
IRELLEGLIPYSQRHFSRIDRLERSTFLLDYTLIGMSVIEPEPVRSDDAMQKKGSKKRKS
KKSSDTERDASIMRLFVQVGCGENVLGLGTWGSGVFMGEQGLIMRMGSGVFMGSGASKSQ
KIVKLLMNECIISICTGGSNCLQNFFLCRAAYNENGSWCKELYNSS
>Sgl15245 E3_adaptor/Cullin_RING/SCF/F-box 19.5 2.6
MSFRSIVRDVRDGFGSLSRRSFEVRLSGHLRGKSHGSVHELHDPPIVIQNSKWASLPPEL
LRDVIKRLEASESTWPARKHVVACAAVCRSWRDMCKEIVRCPELSGKLTFPVSLKQPGPR
DGTIQCFIKRDKSNLTYHLFLCLSPALLVENGKFLLSAKRTRRTTCTEYVISMDADNISR
SSNTYIGKLRSNFLGTKFIIFDTQPPYNSSQSSPPGRSSRRFYSKKVSPKVPTGSYNIAQ
VTYELNVLGTRGPRRMHCIMQSIPNASLEPGGNVPGQPELLPRNLEDSFRSMSFSKSIDT
STEFSSSRFSDIAGPRDDDEEGGKEKPLVLRNKAPRWHEQLQCWCLNFRGRVTVASVKNF
QLIAATQPPPAGAPTPSQPAPSSSDHDKIILQFGKVGKDMFTMDYRYPLSAFQAFAICLS
SFDTKLACE
>Sgl15267 UBD/Alpha-Helix/UIM 16.1 0.8
MADQEDEELQMALKMSMQPSNSPPEPKRSKPRDSVNNAASIDGAPPASEESPELKSRRLQ
RELMAAAAERRRMANAPIASAMEGVSVSKGHGADVVIERECGVGGGGGSGSGSESKSVKK
REDFGVELSVAEANQLFFMVFGGSVSKEVIAQWTNQGIRFSPDAETSMGLVQHEGGPCGV
LATIQGFVLKYLLFDPEGSSNNASRTPQRSWKHESVTPENFASLSEETKKRALVRSMVEI
LFRCGNNKSAVIATLDVLDQNDERTSDEPQDEIILKALEGLSVESASDLQKTLRVTSYTS
SASAIQRVEMMLPVFESRMGAMLFLISALLSRGLDSIQADRDDPSLPLVTAPFGHASQEI
VNLLLCGQAVANVFDERIDLGGGMFLKGVSTNVEVGFLTLLESLNFCKVGQNLKKPKWPI
WVVGSESHYTVLFSFHPSVQDENEMEERESRVRRAFDAQDQSGGGGFVSVEGFHQFLKET
NIKLPSDKLDSLCSAGIIVWSEFWQILLDLDKNLGGFKDSSGLMGKKVFDLYHFNGIAKS
VSNGNQSDTPLQRPRLTKLSVSVPPKWTPEEYMAERAPSSSSSGNDTGGSNATKADVPKP
PQHAPLVDCIRTRWARANCNWTGDPPSIV
>Sgl15339 UBD/Alpha-Helix/UIM 14.5 4.7
MADQEDEELQMALKMSMQPSNSPPEPKRSKPRDSVNNAASIDGAPPASEESPELKSRRLQ
RELMAAAAERRRMANAPIASAMEGVSVSKGHGADVVIERECGVGGGGGSGSGSESKSVKK
REDFGVELSVAEANQLFFMVFGGSVSKEVIAQWTNQGIRFSPDAETSMGLVQHEGGPCGV
LATIQGFVLKYLLFDPEGSSNNASRTPQRSWKHESVTPENFASLSEETKKRALVRSMVEI
LFRCGNNKSAVIATLDVLDQNDERTSDEPQDEIILKALEGLSVESASDLQKTLRVTSYTS
SASAIQRVEMMLPVFESRMGAMLFLISALLSRGLKTPAPPSKKKRPAPPKKGGPPLKKPK
KEPQAVGSSGSQDKPIVPLPASQEPISLFIRCKGMKTWKRGLTKQYEQLRKENDSNKEFY
HHEREQLQVKMQLTIVSQQSELFLNERLVPTNVENSDNDLEVDAD
>Sgl15382 E3_activity/RING/RING 14 0.2
MDASQEALYEGCSTFSKLSFLLHLFHLKCLYHWSAKSFTKLLELLIDAFFQIKEFPSSYY
EAMKLLVNYWFSEQGQEAEHGKSMGLIEAWERSHMRKDGSFVEGTTTEDFLLRGDSTCEE
DLEEEAFHDVMNGGEIPERPKGFGFGVKKSDVYGVPGLIRKQGKEDLEKRNEELTMKYTE
NNNLLKTVVTQFSDILDAMRNGKALSQLIDAAQSALVMATKQVGDSNADATGGDGSRSET
TNVASKS
>Sgl15410 E3_activity/RING/U-box 107.8 0.3
MATKNETQLCVTIPAYFKCPISLELMKSPVSLSTGITYDRSSIQSWLDNGNTTCPATMQS
LSSPSFVPNLTLHRLIHLWSHSHSYTSSLSPSSPSLSSLLVANPKDITLPLKKIFDRVKK
SEANRRVLDESDEFLCSLVELMVKSDEVCDLELIFLILEVCDEQKIKKLMTMKLFDCLEK
FVFVLRNGSVESKIAVAKIVTKISTEKETKRLLIETKDLISEMFKLVESHFDHLIEAGLA
ALISVASTKSVKIELVKLGMVRRLREIIVERFNEKTIQCSMEMMEVMATCTEGRAAICKD
EDCVAEVVKRLMKVSEKVTEHGVTVLWSVCCYFRDEKVKEIVGRSNGLGKCLLLLQSNCK
PIVKQMCRELVKVLRSDYSKSCLGGYNTKTIHIMPY
>Sgl15444 E3_activity/RING/U-box 106.8 0.2
MATKNETQLCVTIPAYFKCPISLELMKSPVSLSTGITYDRSSIQSWLDNGNTTCPATMQS
LSSPSFVPNLTLHRLIHLWSRSHSYTSSLSPSSPSLSSLLVANPKDITLPLKKIFDRVKK
SEANRRVLDGSDEFLCSLVELMVKSDEVCDLELIFLILEVCDEQKIKKLMTMKLFDCLEK
FVFVLRNGSVESKIAVAKIVTKISTEKETKRLLIETKDLISEMFKLVESHFDHLIEAGLA
ALISVASTKSVKIELVKLGMVRRLREIIVERFNEKTIQCSMEMMEVMATCTEGRAAICKD
EDCVAEVVKRLMKVSEKVTEHGVTVLWSVCCYFRDEKVKEIVGRSNGLGKCLLLLQSNCK
PIVKQMCRELVKVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXEKRL
>Sgl15470 E3_adaptor/Cullin_RING/DCX/DWD 29.8 5.5
MASGLCKGRFMNEVESLCGHTTPVESLAFDSAEVLVLGGASSGTVKLWDLEEAKSEFVYV
LHFIYPPFVRWVVSGGFDNVVKLQLQPSQVNYHSDLVSVRVTVSMSVILRETRLGKGKGN
AGGSSQKGGAEEEKYWKACHCDAEMRMEYKVLVLGSACCSSAATTCSSADEVSFASSGFM
FVYGLLQGPDDELFPAQEVLLHIQTRIVDLVPDKDNIVTIRLLVASSDIKCLDEGDGSLA
KLKKLTGADAEVLPKEKVPAFVSGSDELVQCWCWGLHAALRLRLPALRLMSCLMIIVSCD
CQGPDDELFPAQEVLLHIQTRIVDLVPDKDNIVTIRLLIASSDIKCLDEGDGSLAKLKKL
TGADAEVLPKEKVPAFVSGSDELVHVLKCFLNYVKLFDDLSVRFLLFSLLL
>Sgl15511 E3_activity/RING/RING 30.1 6.6
MATDPKVHIPCDHGSDNNLPSSSFCNRVNIRFKYDIFEQCTFHLSNGIKIAMPFCTYKHD
QETAPLSLNPYCHRCMDTLTEFFVPLGYTKDESTCVLDFIRGNFESRHTITSDDLDLLYC
ADLYVRVQYDCSSNTDSLLEWAIRTSNEIFIEKVPTPTSFEAIDAMERLTASTPDVGATT
TTCAICLEEILKNNDQVGRRLPCMHDFHETCILEWLLKNHSCPLCRFQLPPNMDSFIIMK
YK
>Sgl15679 ULD/UDP/UBQ/UBQ_Other 24.7 0.0
MVEFLEGHAVSLSSINTIHLKSHSSLISVSHSNSLPLASALNPAGVSPFRRHHLQEKRKK
IKMIEVVLNDRLGKKVRVKCNEDDTIGDLKKLVAAQTGTRHEKIRIQKWYNVYKEIHDGM
GLELYYN
>Sgl15693 E3_activity/RING/RING 29.5 5.1
MMAVSIDCPHDDDSYANNIDQRLVVRITTRSYQHIVYEDQNNSTHLVSREPQPCSRLNTY
TRSWNSLCPLCKQEFIEFLEQRGFNSDEAYEEYTCLDSVVQEKLHDYYFHDQRNHRRYNE
VVYHEVCLYAPHRVCSEEEYRALVGEGVVFESIVVDSPVPASESAIQGLELVSDVQESIK
EHNVCAICLDGLVSEEVEQESEDNKSKKLRDTVIVRLPCKHLYHRGCVVEWLGRNHICPC
CRFPLPIDYDQVSI
>Sgl15740 E3_activity/RING/RING 10.2 10.2
MAKVSRVRRLKYRCRNGKAERVSSCSHKIFKDIKKPSRLSEKKDWEDATCSVCMESPHNA
VLLLCSSYHKGCRPYMCATGHRFSNCLEQYKKAYSKGIPGEITPSLNHGWSEERMDEMSE
LLCPLCRGQVKGWTLVEPARKHLNKKQRTCMEDNCSFVGNYKQLKKHVKTEHPWARPREV
DPSLEEKWKSFERERELSDVMSTLPPGTIVFGDYVIDPNFNPFIRDYDLEVDDLLDDDDD
LEPTVFGANRIRSGGFQLHRTSGRNYDSFDDDDDDDVGIHRHSAFSRGDDRAPVSRNNRR
MFILERSHRRRRRE
>Sgl15763 E3_activity/RING/RING 28 8.6
MGRFLLTTHLTSSSSSFTTATTTTNDTTDLPCTDFCDPSCGDFDACYAFPAIPDDTLPPP
PPLLPPPPPTTTVATPSSSNFIHDLFNLSPIAIVIIIVLASAILLISYYAVVIKYCSLLT
RLITRRDLARMQPNQSSDPNNPRTTAANNQFVDHPIWLISTVGLPQSMINGITVIRYKED
GLIDCTDCSVCLSEFQQGETLRHLSKCRHAFHIECIDTWLRSHTTCPMCRASITVPNPNS
PTSGHSGRGELTQVVDSDSNDLELGNTQHGISTSNHNNNNNNNSNDSVTLLVGEDRGTQT
GEYVAATNILEILLRRSNSVDYQNSGMQPNVSSSNSSASSSSRPLHQRMSLKRSYSWSEK
VFCQNDRNSVMSP
>Sgl15766 E3_activity/RING/RING 31.2 6.8
MPWTFPSPTNVTLLGFLLLLLFAPLVTAQQPPPWPESNKNYNSPMATALIVMIIVFFSVG
FISVYLRHFIACLGFDAYGGLRRGGGGARARDPPNRGLDPTILNTFPTFLYSDVKIHRVG
KITPLECAVCISEFADNEILRLLPKCNHVFHPHCVDLWLASNVTCPVCRANLEIQPYNNN
SGTSDDDGESVGRRRPQAAASDNNNNDQVIIRVEETTTTTTTIPGTEGMVKSPTQELLHR
LNLSESGRIIRLPRSHSTGHSLVGDSDRFTLRLPEEVRNKLIINDNNYNYNYNYNAIVSP
RVGYRPTNMGCTDPPNKPDRWRFSMSPPFISRPNSPKLESPTPNNNNSNSNNTPGRLLRS
PKSLFRSLKSPNKSPLHRVVSCNDIGERSSNRLWDNRTPQDLDLEDQDQHSHKQQFG
>Sgl15767 E3_activity/RING/RING 26 9.7
MPYLIQVYHLSTCFLLILITSISLYPSFTTAESSSSSSNDSYNGSPLPTTAIIIVAVVFV
VGIATCYIRHLIVCFRGYIFGTQSGGDGAGLRRRDAPRGLDPSVIATFPTISFSDVKLYL
TAKTTPLECAICIFEFVDQDLMRLLPTCSHVFHPHCIAPWFSSHSTCPVCRANLEILPDT
QMTTSPESLAHVIQHQRSVDVDQSEPSNQEQIVRPHDHDHHHSDVILQIRETSDHNKISS
GEHKSNSNGVGERSRKFQRSHSTGHSLVENCERFTLRLPEEVRNKLVNVKDNNLNGLSNN
PLVSPRCGYRAWSVTTTNATMSVKPDQQWRFTMSPPFISKSGSSPDIAGSSNNTSSSNNN
NGTNNIVGMMRTPKSFFKSMKSPSKSQLNRVVRCDDHDIGERSSDKLWPNRTSQELGLEH
HQ
>Sgl15768 E3_activity/RING/RING 29.3 8.3
MGRIRNKHFLLLLHILLLLSTALAQADGKGKKSGKWWSTPLIMVVYIVFFLVAAGLAFCI
RHYRDRRSLMEHPRYQRRAAEGGLEAEEIESLPSLRYSEIKMNQIVKGKEQLECSVCLAD
FKDQEVVRILPDCLHVFHPHCIAPWLATHVTCPICRSSLEHRQGSSLSMSSIFDDGTSGH
PSQRFDYSGDQVYEANGDDHVITVDIEESSPTSHSSQLNVGAVVTNSRMKLQRSYSTGDL
TAHMIDRYSTTTRSSSISSLLMPKEITPKNEHRKIFNKENSWSCFSPKSDSFVDYS
>Sgl15769 E3_activity/RING/RING 32.3 7.2
MQNKSLIIILSYVVFLLQLSPAHVAAQESFKGNLGEPFAPSTIIIVIIAVIFLFTGCLAV
VLRRFSDGCFGLHVIPIDHPDFTSDGQLTTKGLEADVIKSLPTYFYADVKQHRKAEVELE
CAVCLNEFQDPETLRLLPGCSHVFHPRCIDPWLAAHVTCPVCRQSLLEPPLTGKTTNTPH
SIIDIVPTTTQVDQSNGPAHAGAQNDNHDDEDDMVHDGVKKMIVGKFPRSHSTGHSIKRH
TLVLPEDVLVQNNLVNRTKSGLRLSGMISPRSGYKCGWFSMTPPITTINPRTKSLLSSGL
IKSSSSKNLTTIPHVKTTSDRCWNNV
>Sgl15830 DUB/USP 249.5 0.0
MLVPGDLGFRVAVFFIFLVFPVFAFVLRRKWRIAVARQQEINRLLVLASEEAARAEVEAT
FGYSSSVSLPSTHRLCAVCFTPTPNRCARCKSVNYCSGKCQIIHWRQGHKDECHPSVYHS
DSCDEEVSFVEDADKKFYSDGDISVSENGGFQHDEQAITSQEKTGFTASAYCPPELSVKD
VQNEVSHPSLADDPVSHGIAGASQLHPSSSSDGICIDDSGSEIDSIHDLNSDPYDSCSPM
FDNLETDSSDSNLEQPKPLVENSHPRVASNGNISGLSELKEEASGSITGSSGLSISRFDK
NLTKPLVATPGFWDGSLDYCRSKKTVQCTDVKPEIGNIGDPSSGMPSQGPEASPDVYPGT
FSAVKLVAEPASAKKDPKDPTQVKSSMDLGSREVVTTVKVTSSDKELKSGEVGAADENLE
GGALPACISEKTNDQIRNTKDALHSRGSKKAGLSPKALNGSPSGLKEPTASTRKSVKASA
DASMPVHVARSAPNAAVGLKTSMLKVVEQLRAPKPMKQGDDVVRNREKPVFSYETFVKLY
HWSKVELRPFGLINCGNSCYANVILQCLAFTPPLTAYLLQGLHSKSCAKKEWCFTCEFER
LVLKGKEGGSSLSPIGILSQIQKIGSHLSNGREEDAHEFVRYAIDTMQSICLQEAGVNAS
GSLHEETTLMGLTFGGYLRSKIKCTRCRGKSEKQERMMDLTVEIGGDIETLEDALRQFTG
TEPLDGENKYHCGRCKSYEKAKKKLNILEAPNILTIALKRFQSGKFGKLNKAIRFPEILN
LAPYMRGGSDKSPIYQLYGVVVHLDVMNAAFSGHYICYVRNVQNKWYKIDDSKVKAVEIE
RVLNKGAYMLFYSRISPRAPKSIRSALVSRDLPIKSKMPAADASRVNVRSTTSRQRDPFV
DANHNFDNLASLGYIHQSETHPLPVRNIHDFDSSSDNSSLFSQSDEVSSSTTDSNRESIS
ADDFSEFIFGHNAFFPHSSDSDTSSSSSSSSPQYTRHSPLSNPERYASAFPDSNARSDPS
EDPSCSKAPLSRGEESGSVGGVSFLHSNSSSKQGRKVVNISSRETDAEKLGRTNPLENGK
PDVYQRQSGRKKSD
>Sgl15840 DUB/ULP 147.2 0.7
MKTRDTSVYDFKEEDELTDNCYPWSKLTNPKFGDDVALTKYQFLQHASTGSITQTKEFHS
LEKIHVVTIDDDDRVFGNDISTAAQDSTDEAASKQSEVSGAISDRIVQEHCHINGDSVEP
KNSLLNMEIRISCSHGFPPGTSHTSSSIPESPCSNGSAEAEAGFLDDCDSMQTNSPSTSG
SEQEENYVPLDGQAHDQSISGWTMEETDAIYTDYVSYGDKYFPACFIYFSKSSLKIVTSV
SEEEADKSSFEWSVNDLHSIESQWCNKVSTAKVTVRILPKDAVPAENAHSMTGIEMFEFL
VHDPYWLDRQEAIMALDVRYKAVWSIGLNGRNCEGGPFPLESDDSSLDPYIPIFQEPFEE
VVYPKGEADAVSISKRDVDLLEPDTFLNDTIIDFYMMYLKNAIATTDRHRFHFFNSFFFR
KLADPDKNSSGVFDGKAAFQRVRKWTRKVNIFDKDFIFIPVNYNLHWSLIVICHPGEVAT
FKDENVDDSVKVPCVLHMDSIRGSHAGLKDLVQSYLLEEWKEKQKETSEDIASKFLNLRF
LSLELPQQENCSDCGLFLLHYAELFIAEAPENFSPFQINEFDSFLKPDWFMPAEASLKRV
HIQRLIYELLEGPLSENASLRNNETQPSAFPESKEIDNGIKIISARRSPRKTWNPLHSHP
VQGMELGLLDMSLYRTSDCTNVSGLGMRDLLEQYQQYDQEASLGRPGSLMPQIKEEVEAA
DHLASSSLGQIKLQTMDGVTPEACDMGYTPTEIHGGFHWDSGLPYQGDLDKSLLPSSNSS
DDDDDDPEDMVIIECEQDVEGATSGENKILDQPKENVDNFTESYESASSDMMETPAEDSQ
ELAKIYGSNDLEDSPFCSRKEAKEESPQEEAEEASLKEEAMEASHQEEAVESSHQEKAME
SSHQEEAKEASHQEEAKEASHQEEAEKASQQEKAEEAFQQEEAEKAPHQDFEKFDEVGNA
AGIDVIVEDSSTDTDEEHSAKRRRLTAPGDGEIELVTSLSKEVQV
>Sgl15869 E3_adaptor/Cullin_RING/SCF/F-box 21.7 0.0
MASDLNSTIVAELEAAYRWRTAQYFVTQRPWLDLYGVRVSPVAAFGSVSNKPSLDPALIH
RALPDELLHEIFVRMSPYHLGVACCVCRKWRYTIRNPVFWRNACLKAWQLSGVVDNFKLL
HSKYEGSWRKMWHLRPRVRTDGIYVSRNTYIRAGIAEWKVTNPVHLVCYYRYIKFYPSGR
FLYKNSSEKLKDVAKFMNIRASKTDRVFRGQYTLSDDKVEAAILYPGMRPTVLRIRLRLR
GTTAGANNRMDLVSLVTSGVNDNEANHEEDMLDLVEGWQDDETHNPDVPAVSHKRGLTPF
IFVPIEEVETSILNLPVEKMDYFVPD
>Sgl15871 E3_adaptor/Cullin_RING/BCR/BTB 59.7 0.1
MYESVMGLSAQLQSDREREKMGGDTKVDTISRLAQWKIDNFGPCSYKKSDSFKLGLWNWH
LAIEKNRYLYIRLFPEPSRVSKDQPPIARFILRVSNAGVSRRPYVSPIHERMLRNSDDFV
WPVDTTFYGRFIIDVEFLDLKIGALSGGQPVSIWPAEGNMQSLSTQSALQTMSRMLYEGI
LSDVTINTSDGSMRAHKAVLSASSPVFQSMFLHDLKEKESSTIEIDDMSSESCMAFLSYV
YGTIKPIEFWKHRLALLAAANKYNMSDLKQACEESLLEDINSGNVLERLQEAWLYQLDKL
KKGCLTYLFEFGKIYDVKDHISSFFLTADRDLVAEMFQEVLTVWKPV
>Sgl15913 E3_adaptor/Cullin_RING/DCX/DWD 37 8.3
MKLELCKTDPDHVGLRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSGSKVVGCFA
GHPTEVIVALIDEITQLTCIVTELDAGFVKSTSDPLIVSTSLKISSEGITALEALMIVVR
SVHNCRVLGYNGGIQKLVALIKAAVVQLKAIAGAVAGEETLSDVVLDTLELLQKLLVHVV
SILCSFIDLNSDAYEMANIYSNITFSLSSGGASLIDPSNTFKVRHGKMHPWKQTAIMSVM
EAGGLNWLVELLRVMRRLSIKEQWTNLSLWYLTLRALHSALSENSRAQNHFRSIGGLEVL
LDGLGLPSNSALASQKANTLGRQRFENILLALFQLHVLSLEVLREAVYGNLNNLQFLCEN
GRVHKFANSFCSPAFALQDFQNRSKEFPVEGSLENLALTSKYGSDEKMRTKELAVIPITG
EFIKYWRTYALTLSQSFCSFILSLEDAKSDSTDGSTSRQNMPISSLFSELSIRWILRVLL
IVFPCIEACSNEDELPTYLRMFVCILQLQVLHALRQVLRSSPKLLEVFRAEKLWELVFSE
HFFFGATLKDSEVNCSATKLSFLSSSGNDNNTEVPAEKNLRIEVVSFAELAATLKETTHN
LSECSALLDALEHSALDPEMANVLCNSLLRTLEHAREKTLASFKELNAMSRVLKVACIQA
EEFRSTDASCNEALTSVEDIVPEDFHNSDCSATSHHLNRSIAASVELFKAYFCAADDAKS
LVLHNEECINCLFNLFWDRDLRNLMLGYILDLMKAAPTSKEDQTANLLLCSRYLETFTQV
KEKEKDFGEVSIELLSGMRAMLQMDQEYFQDLFRNGECFIHVVSLLTGVIDTKNAEKLVL
DVLHTLISLLSNNDVSKAAFRDLVGKGYQTLQSLLLDYCHRQASECLLNALLDMLVDGKF
DAKGSPSIKNEDAIILYLCLLKESSISVQQEGLNIFLQLLRDSISNRASCVSAGMLSFLL
DWFSEEDNDSVILRIAQLIQVIGGHSISGRDIRKIFMLLRSEKVGKRQQYCSLLMNCILA
MLNEKGPTAFFDFIGDDSGIILKTPLQWPLNRGFTFSCWLRAENFPRCGTMGLFAFLTEN
GKGCFSLIAKDKLIYESVNQKRHCISLQVNLAKKKWHHLCITHSIGRAFSGGSLVKCYLD
GHIVTSERCRYSKVNDPLTKCSIGAKILLPFSEEENLVYSIKDISPFLGQIGPVYLFNDA
LTPEQVMGICSLGPSYMYSFLDNEYVLSSDNPLPGGIFDAKDGLAAKMIFGLNAQASTKR
ALFNVAPLMEHAIEKNIFEATILPGTQLCSRRLLQQIIYCVGGISVFFPLFTQSHWYENE
EQSDSRNPLLMPISKERLTAEVIELIASVIDENVENQQQMHLVSGISILGFLLQSVPPEQ
LNLETLSALKHLFNVISNCGLSELLIKDAISTIFLNPLVWVFTAYKVQRELYMFLIQQFD
NDPRLLKSLCRLPRVLDIVRQFYWDNAKCRSSGAGRPYLHPLTKKAVGERPSKEEIHKIR
LLLLSLGEMSLRQNIDDSDIKALIAFFEISQDMACVEDVLHMVIRAISQKSLMASFVEQV
NYIGGCHVFINLLQRGHEPIRLLSLQFIGRLLVGIPSEKKGLKIFNLAVGRSKSLSETNR
RTHSRIQPIFNAISERLFSFPLTEHLCATLFDVLLGGASPKQVLQKQTLPERQKSKGNSS
QFFVPQVLVLIFKYLSDCKEVSARVKIISDLLDLLDSSPSNIEALMEYGWTAWLTASMEL
DVVKHYKLESVGQTEDEIIEQNSVRTLFCVVLCYFLSSVKGGWQHLEETVNFILMHFEKA
GVSYHYLLRDIYEDLLQKMIEFSHEENVLASQPCRDNVLYFMRLIDELLLSEIDHKLPFP
ATTSEFSPDLLEVEGFNDLGTALYDALQGESVERMSRNPQATNQLTHNEDVIADENWWTL
YDCLWVVVSEMNGKGPSKTLPKSSSFAGPSLGQRARGLVESLNIPAAEMAAVVVSGGLGN
ALGGRSSKNVDKAMLLRGEKCPRVVFRLVVLYLCRASLQRASRSVQQVIPLLPSLLLSDD
EQSRNRLQLFIWSLLTVRYQYGMLDDGNRYHVISHLIRETVSCGKSLLATSIVNGNDSSD
PGSAPADIGAVHNLIQKDRVLIAASDEAKFIEASKADRMRQLVDLQTRIDENILTDSGQK
KAFENELQSSLTETLASDDSRRAAFQLACDEEQQVVAEKWMHVFRSLIDERGPWSANPFP
NCAARHWKLDKTEDTWRRRPKLRQNYHFDEKLCYPSSGASENEVTAVPCENKSGAGIPIP
EQMKRFLLKGIHRITEEIDPEASESEEESSDSKGMNSEEVPDGQSSELLKDGDQMDAVHE
RKESSSPAFETDNGQVLVTVPCIMITPKRKLAGQLAVLKNVLHFFGEFLVEGTAGSSVFR
TFDSLKNSESEKVDQLNEVEKVKFLKLPVDTSLFSEKHNAIGTLEKQLKSIKRHRRWEVS
KIKAVHWTRYLLQYTAIEIFFSNSVAPVFFNFASQKIAKDVGSLIVTSRNDLLFPKGSAK
DKTGAISFVDRRLAQEMAEIARESWRRREITNFEYLMILNTLAGRSYNDLTQYPVFPWVL
ADYSSETLDYNKSSTFRDLSKPVGALDPKRFEAFEDRYQSFTDPDIPSFYYGSHYSSMGI
VLYYLIRLEPFTALHRNLQGGKFDHADRLFQSIEGTFRNCLSNTSDVKELIPEFFYMPEF
LVNSNSYHLGVKQDGEPLGDVCLPPWAKGSPEEFIYRNREALESEFVSSNLHLWIDLMFG
YKQRGKPAVEAANIFYYLTYEGAVDLESMEDELQRSAIEDQIANFGQTPIQIFRKQHPRR
GPPIPITQPLRFAPGSISLTSLVSSFSYTPSALLYVNVFDSNVILVNQSLTMSVKLWLTT
QLQSGGNFTFSGAQDPFFEIGSDVLSPRKIGSALAETVELGSQCFATLQMPSENFLISCG
NWDNSFQVVSLSDGRVVQSIRRHKDVVSSVAVSSEGSILATGSYDTTVMVWEVCRSRALE
KRVRNSQSEIVRKDYVISETPFHILCGHDDIITCLHVSMELDIVISGSKDGTCVFHTLRE
GRYVRSLRHPSGCALTKLAVSQHGRFVLYSDDDLTLHLYSINGKHIASSESFGRLSCVEL
SACGDFLVCAGDQGQIVLRSMNSLEVVKKYHGIGKVITSLTVTPEECFLAGTKEGNLLVY
SIENPQLRKTSLARNTKYKPSIVG
>Sgl15930 UBD/Alpha-Helix/UIM 14.4 0.1
MATLRSTLPSRLRQLFGSEGSFGPSIQLDSETPPKIKAFIDKVIQSPLQDLAIPLSGFRW
EYNKGNFHHWRPLFHHFDTYFKEYIAKRNDLLLSDTITEDDASFPKHAVLQILRVMQIIL
ENCHNKSSFDGLEHFKLLLASTDPEVLVATLETLSALVKIPPSKLHVSGKMIGLGSINSC
LLSLAQGWGSKEEGLGLYSCVVANEKSQEEGLSLFPSDAPDRDEKSQTRLGSTLYFELHG
VSPQRSGESSSDVKPSSSTMIHMPDLHLRKEDDLLLLKQCIDQNNVPPEQRFSLLTRIRY
AHAFRSPKSGRLYSRICLLAFIVLVQSNDANDELVSFFANEPEYTNELIKIVRSEETISG
TVRTLAMLALGAQLAAYSSSHDRARMLSGSSINFAGANRMILLNVLQKAISSLKNSNDPS
SLAFVEALLQFYLLHVISTSSSGSIIRGSGMVPTFLPLLEDSEPAHMHLVCYAVKTLQKL
MDYSNAAVTLLKDSGGVELLAQRLQIEVQRVIGTGKSDDNLMVIADVSTEDYLYGQKRLI
RALLKALGSATYAPLNASSSQSSHDSTLPSTLSLIFGNVEKFGGDIYCSAVTVMSEILHK
DPTCFAILHEMGLPDAFLSSVVAGVLPSSKALTCVPSGLGAICLNTKGLEAVKEASALRF
LLEIFTSKKYVVAMNEAIVPLANGVEELLRHVSSLRSTGVDIIIEIINKISAFGEGSSSG
SSEKVNEGKIMELESGDKGSGSESSSSVVPSSDSAGEGITDEHFINLSVFHVMVLVHRTM
ENSETCRLFVEKSGIDALLKLLLRPSITQSSEGMAIALHSTMVFKGFTQHHSAPLARAFC
SFLRDHLKKALTGFSLVTGSFLLDSKTKLDHEVFSSLFLVEFLLFLAAAKESRWISALLT
EFGGESKDVLEDIGKVHREILWQIALLEDAKVEVQEGAGPASASEPQQVSSSSGAEEQRV
TSFRQLLDPLFRRRMSGWSVESQFFDLINLYRDLGRASGVQRSTSDGLNLRLGSSQQSRE
SGGLDTDSVSRKEEDKQRSHYTSCCEMVKSLASHIMHLLQELGKSMLLPSRRRDDAINIS
PSSKTVVSSFASICLGHMNFGGHMSPSGSEASVSSKCRYFGKVVDFVDGILMDRHDSCNP
VLLNCLYGQGVIQSILTTFEATSQLLFTVPSSPMETDDGNLKHDKKEEPEHSWLYGPLAS
YGKLMDHLVTSSYILAPFTKHLLVQPLPNNNTPFPPDAETFVKVLQSMVLKAVLPVWTDP
QFVDCSYAFITSIISIIRHIYSGVEVKNVSRSTTSSSRLPGPPPNEAAISTIVEMGFSRA
RAEEALRQVGANSVELAMEWLFTHQEEVPEDDELARALAMSLGSSGSDSKEEAASENSQQ
FEEEMAKLPPIDELLLTCVKLLQSKESLAFPVRDLLMTMCSQNDGQYRPNVITFIIEQIK
HCNSVTDRGNGSMLSALFHVLALILHEDAASRETCLKNGLVELVSDVLWQWDAGSSSGTD
ALVPKWVTAAFLAVDRLLQVEQKLNPEVVEVLKRNTETSQQASIVIDEDKQNKALEPSQQ
NVDVDQQKRLVEIACNCIRKQFPSETMHAVLQLCSTLTRTHTVAVSFLDSGGLPLLLNLP
TSSLFSGFDNIAANIIRHILEDPQTLQQAMESEIRHNIVTATNRQSSGRLTVRNFLVNLS
PVISRDPVVFMRAAQSVCQVEMVGDRPYIVLLKDRDKDKSKDKEKEKSLGTDVKPATGAV
APMALGGGQGKLQESKSFKAHKKPPHSFVNVIELLLDTVIMFEPPKKDDSLPEASGSLST
TNMDIDVAASKGKGKAVASESEEKEGQNQDVSASLAKIVFILKLLTEILVTYAASVHVLL
RKDVELSSCRGLPQRGTSGHNSGGLFHHLLHKFVPYCKKAKKEKKLDGDWKQKFASRANQ
FLVAACVRSAEARRRIFTEVNSVFSDFVESAECFISPGNDIVAFVDLLNEVLGARSPTGS
YVASEASATFIDVGLVKSLTRTLQVLDLDLADSLNVVTGLVKALELVTKEHIHSADANAG
RHDNSAKPSDLERTDNSGDGVQAMEAASQENDNSATDVRGDSFNDGHAYGFSEAVTDDME
HDQDLDGGFAPNEDDYMHDTPVDGRGLENGVESVGIRFEIQADGQENLDDDDEMSGDDAD
DGDDDEDDEDDEDEDEQNDLEEDEDHHLPHPDTDQDDHEMDEDEFDEEVLEEEDDDDEDD
EDGLILRLEEGINGINVLDHIEVFGREHSFANETLQVMPVELFGSRRQGRSTSIYNLLGR
SDNTVPSQHPLLVESHPSSVPATSRASENTSDLLFSDRNAEGASSRLDTIFRSARNGRQG
HRFNMWLDDNEQSGGSNSSTIPQGLEELLVSQLRRLDAEQPSDQKAGVDSERNIEPDQLQ
VSETSMGIETPVGSNANNQSLYPPIPSSVAMDSLNPENRLGPASPRQGTDASSMHSQSVE
MQFEHNDVTVRDVEAVSQESGGSGATLGESLRSLDVEIGSADGHDDGGDRHGSAERTPLG
DSMGTRTRRNTVSFGVTPPVGGRETSLHSVSEVAENPNQEAEESGPADGQQMTGDGESGP
IDPTFLDALPEELRAEVLSAQQGQVTQPAGAEQQNSGDIDPEFLAALPPDIRAEVLAQQQ
AQRLHQSQELEGQPVEMDTVSIIATFPSDLREEVLLTSSDAVLANLTPALVAEANMLRER
FAHRYHSRTLFGMYPRSRRGESSRRGEGSGLDRAVGSIASRRSVVGKLLEADGAPLVDTD
ALKGMIRLLRVVQQVYKGSFQRLLLNLCAHSETRTALVKILMQMLMLDEHKLGNQQNDAE
PPYRLYACQSHVMYSRPQFVDGVPPLVSRRVLETLTYLARNHPYVAKILLELTFPQQAHI
PSESGDKVRGKALMVVENQSSDIHEEHCHSVALLLGLLNQPLYLRSNAHLEQLLSLLDVV
IDNAASKSSSSKLESSAPEQQSVSESPTTTTDVEMHATESGTNSSEAVTGPKVEESVVPS
VSGASDSYDARTVLLGLPQADLRLLCSLLATEGLSDNAYSLVADVLKKLVAFTPTHCHLF
ITELANSVRKLSQSAMVELHSFGEAEGALLHSTSSDGAAILRVLQALSSLVSSANEKQED
QVNVDGKDYNVAASLVREINSVLEPLWLELSSCISRIEVYSDAGIELPSSSLSVKSKPST
ASPPLPAGSQNVLPYIESFFVTCEKIDPAQPGTNQDIAVAAVPEVDDASTSASKQQASSP
VSKVDEKRAAFVKFTDKHRKLLNAFIRQNPGLLEKSFSLMIKVPRFIDFDNKRAHFRSKI
KHQHDHHHSPLRISVRRAYILEDSYNQLRMRSTQELKGRLTVHFQGEEGIDAGGLTREWY
QSLSRVIFDKGALLFTTVGNDSTFQPNPNSVYQTEHLSYFKFVGRVVGKALFDGQLLDVH
FTRSFYKHILGVKVTYHDIEAIDPDYYKNLKWMLEHDISDLLDLTFSIDADEEKLILYER
TQVTDYELIPGGRNIKVTEENKHQYVDLVAEHRLTTAIRPQINAFLEGFNELIARELISI
FNDKELELLISGLPDIDLEDMRANTDYSGYSPASPVIQWFWEVVQGFSKEDKARLLQFVT
GTSKVPLEGFSALQGISGSQKFQIHKAYGSQDHLPSAHTCFNQLDLPEYPSKDHLQERLL
LAIHEASEGFGFG
>Sgl15946 DUB/USP 101 0.1
MIIHLMRFSYGSQGSTKLHKPVYFPLELVLNSSLLVTPINEGRKYELVATITHHGRDPSK
GHYTADARYSDEQWLRFDDASVTPVPTSKVLHDQAYVLFYKQV
>Sgl15960 E3_activity/RING/RING 22.3 8.9
MENVDSEEPEKKRPHLSSVSSPMARNSTLSPDSNSVDAALLQYQNQKLAQKIEVQKQEVH
DLEAKLQELKDRQSSYDDLLTNVKQVWNQTIDDLVLLGIKAGGGLDVLQTSDSEDCIQGS
TTSFRAEDFFLSRLLKVESMEGEGGESCFKFDEEFLEQHLFSFLKLLKCVEDFVEDQQRT
TNCVTQESKEILSVEGPGDAIKSNKFEDLMTECAKFLHILVDDLRQKHSDYVDRIQRYVQ
SQSEDDAEIKHITGDIEESVAEAEESRRKLGHLRMRKNLASGNYNPATAVNGTLSSYKVP
DRSMGLQELKDSIEEAEILAIDRLAELEDGREDNAIMLKQLQEIENEIKDDKYVSSSRLY
TLINDQLHHWKAEITCYKALTDTLQSERSYIIRREKELELKTESADHAKATAGNAETRVE
ELELKLRDSVIEKNELEGKMEEAVQDSGMTDIKTEFNVMASALTKEMGMVEAQLNRWKDI
AQEAFSLREEAESQKTLLNRKTSEVKSLGDKCAQQMAESKSLKELTEKLQKEKFELQIFV
DMLGQGCYDNRDLSEIEESERRACAQAEVLKHALDEHNLELRIKAANEAEAACQLRLSAA
EAEIADLRARLDMAERDVYELTEAIKIKDAEAEAYISEIETIGQAYEDMQTQNQHLLQQM
AERDDYNIKLVSESVKTKHAVNSLLSEKQTLGHQFQLINTALESLREHILRSEEQMKTTM
SEALSHCQEDRHLSVSLERAKWELSDLEKELKWVKSVMTSSEKEREQVQRKTVEIQRDLD
IDRHDRKKLEEELKEWKDKVAELTAETGEAAILKLQEEIKECKSILKCGVCFDRAKEVLI
VKCYHLFCNQCIQRNLEIRHRKCPGCGTAFGQNDVRFVKI
>Sgl15992 E3_adaptor/Cullin_RING/SCF/F-box 16.3 0.0
MEHNCIFPHDLVEDILSRLPVRDLLRLRCVCKEWCAVIDDASFIKKHYQVQYSICKVGSN
MPYFITEDREYKIKRTEEAYLLSIHQGDIITLNLTDDLERDSNGVFPNVTDQFYMQCCGC
VNGIICLSFINRIKTPFIDNCFLALWNPATREFKTVAYPNAPGLTYGHGFPILGFGFDLS
SNDFKIFGVFTDDRENDDELVFYHKLYSLNTNSWKTIPNPPPKALGLLPWAMNDGYFDGV
YYMTTDDRQYNCRPSYYEIVSFNFASEVFTVSDLPQEAISLVARSKIHQVMITLYKEKLG
LFVSHEVEEFGLCSIDIWVVTQLNDCGVPLSWQHLFTIEGTLDKLDMQVRSTLMNGDLLL
TYLIPTEDMPSFEDLIKTPTFYHSIYNQSRGDYKKFEIDLVAFFRYVESLFSISSMLV
>Sgl16047 E3_activity/RING/RING 34.5 5.3
MGFGVSIKKLFFGLCLILIFSLSSASVVLEGKNITYVFEDIEANFAPPLDSSGVCGKLYI
AEPLDACSSLKKAVDDSRICNSPFALIVRGGCSFEDKVRRAQIAGFHAAIIYDNEDGGAL
VAMAGNSVGIKIPAVFVSRATGRKLKNYVKPGMKVWLFASYESSAWSIMAISFISLLAMS
AVLATCFFVRRHHVRRERPHVRVREFHGMSSRLVKAMPSLIFTAVTEENCTASTCAICLE
DYIVGDRLRVLPCKHKFHTVCVDAWLTAWRTFCPVCKRDARTSNGVPPASESTPLLSSNP
SSVASTPFSSFRSSSVRSSAIQIASPSHQSRPSSQNPSVASSPQIPRPLHSHQNQPSPYM
SMSRSSLDLRNMSSQRSYTSQYMSPGSVGYPSVSPLNTRYMSPYIPSPGNASSSYLRSSS
MRYPNPLHYSESAASFSPYNSAQSLPGC
>Sgl16067 E3_activity/RING/RING 34.5 5.3
MGFGVSIKNLFFGLCLILIFSLSSASVVLEGKNITYVFEDIEANFAPPLDSSGVCGKLYI
AEPLDACSSLKKAVDDSRICNSPFALMVRGGCSFEDKVRRAQIAGFHAAIIHDNEDGGAL
VAMAGNSVGIKIPAVFVSRATGRKLKNYVKPGMKVWLFASYESSAWSIMAISFISLLAMS
AVLATCFFVRRHHVRRERPHVRVREFHGMSSRLVKAMPSLIFTAVTEENCTASTCAICLE
DYIVGDRLRVLPCKHKFHTVCVDAWLTAWRTFCPVCKRDARTSNGVPPASESTPLLSSNP
SSVASTPFSSFRSSSVRSSAIQIASPSHQSHASSQNPSVASSPQIPRPLHSHHNQPSPYM
SMSRSSLDLRNMSSQRSYTSQYMSPGSVGYPSVSPLNTRYMSPYIPSPGNASSSYLRSSS
MRYPNPLHYSESAASFSPYNSAQSLPGC
>Sgl16119 E3_activity/RING/RING 15 17.6
MEVDEPPTNDYCSICHGEFNIPCQANCSHWFCGRCILQLWDHGSALQPCRCPLCRRPINL
LIPTDTYRRQRDNPEISSILSRLEVYNRQFGERSNDLVQRLRDLPFLLRRLSRDMLDPQR
SLPIVIKTRVYLAVILSAIYLVSPVDIIPEGILGVFGLLDDLILLLICLLYVAAIYRSVL
VSRHGG
>Sgl16134 E3_adaptor/Cullin_RING/SCF/F-box 20.7 0.0
MTTKRKCLIEERYNEMKKKHMIFIKMVEERAAKMQTSWVSFLPNDVMFKIFLLLPVKSLL
SFTSVCKAWYKLIYSAEFVEAYNAQAQTTPIVFRLKGVEEQRLNTYHVETQIKQSENFNF
FPCGSKKRRSKFIHYLEMENGNCKVIDLNISLSGAVLATCNGLILINSVNKLLGTHVCFP
REKPLVHSQENLGRLIVMNPMTRKLIGFPPGTLPSELHRESYGLAFSQTKGVYKVVHLFM
DSSAHIACEVLSLQTRLWKAVDGPSRLLFNNFGQPPISTAGALHWLPGSPSNDYIISMGA
DDEQFSSTDLPTSMGKYDRLVEMGGFLSFVKTLDKCIIEVWLLKALEGSEWVKQYTICCI
DFVYMLEYMVDDYGAQSEHYFVPAFALNAKEMVFRRGNQLYSYNFELEQFREFNMDHGKL
KGYDSIMPHSNNLATWETLESLS
>Sgl16165 E3_adaptor/Cullin_RING/DCX/DWD 19.8 0.8
MTKNITSSNSPISDELDLDSFLRRHNATFSDEDEEEDDQKPQISDTLHRTIDDILNDSSS
DSDHDVVSVSSSTPYSKTLISGEKVVNSTQTKFNLIQRLKSDEFASRKPPIGSQNSRNSS
IFGSGVSRKPGAALAAAAAASRNVRTPRSAVMMSRRALSESLEGKVSDDELLGFVKDDVK
FEGDNLNEVVGEVVCERENDEKDEVMMDSFDKCGVRGCEGSNIKEGIEVKQKGDDVEVNG
RGDEKGGGELENGEDFGRKMEAVASDEKVEILDVERVDSGGFAEEEAGCMLDVEEKGMGE
GRDVDENFVEGFGLSLEVKNEEEEEDSGFVPRQVQEAGMSDESGTGRDELNFTSDDDEER
IAQLEDEMDSESAEDTLRSVKKPLELAEELEIKQASTGQDWEEGAAAQPMRLEGVRRGST
VLGYFDLNAENILSRAIKSQAFIRDYGTPQVIAVHQNYIALGMSKGVVVVVPSKYSAQHP
DDMDPKMLLLVAQADRSQVPVTSICFNQQGDLLLAGYGDGHITLWNLPRGTVAKVITAEH
KAPVVHTLFLGQDSQATRQFKAVTGDSKGLVLLHEFSSGLLVGVTVKTQCLLDGQRTGTV
LCASPLLPDDFTCPGNTTGSSSSSSSSIGSVMGGASPWKFFNEGSPLSEEGVVIFVTHQT
ALVVRLTPNLEVYTQLSKPEGVREGSMPYTAWKCTTQPRASSSENVNPEALERISLLAIA
WDRKVQVTKLVKSEIKESEKVEPKESGKWTLKVCGSWTLESAAVGLAWLDDQLLVVLTLA
GQLCLFTKDGTLIHQTSYATNETGEDEFMSCHTYFTNVFGNPEKAYHNSLAVRGASVYIL
APRHVVVSRLLLWRERIEVLRNAGDWMGAFNMAITLYDGQAHGVVDLPRDLHTVQEAIMP
YLVELLFSYVDEVFSYISVACFNQTGKVEEVDDSLNKSISASSEIKEQFTRVGGVAVEFC
VHIKRTDILFNDIYSKFVAVLHRDTFLELLEPYILKDMLGSLPPEIMQALVEHYNDKGWL
QRVEQCILHMDISSLDFNQVVRLCRENGLYGALMYLFNKGLDDFKTPLEELLSVLRNHER
DATVGYRMLVYLKYCFSGLAFPPGHGKLPLERLPSLRMELLLFLLQDSGGPKSQTGASLT
STGAYLNLHYLLELDTKATLDVLRIAFVEDERFKLDQSLHDASDTNVDNLKNNDSVAGDQ
DLLVQKIVDALVIVLDIDISQSVRSTGSDDTGMVIWPTKKDIGQLIEFIASYVASKRANV
SKSVLSQIIEYLTLENHLEVNDCVQMSESKKKREKKVLALLDVVPQTEWNASYVLHLCEK
AQFHQVCGLIHTIRNNFFAALESYMKDAEEPVLAFSFIDGILLQLSESEYVAFQSVVTSR
ISELVTLSRECTLCLVSYHLNKEREHVLSKLRSTPRSLFLYLKTLFEVYFSGNLDFSSIR
VDNALDGPWGRKNVTKNSLDAYMKRIAEFPKFIRNNPIEVTDDIIELYLELLCQYEPDSA
LKFLGTCENYRVDRCLLLCQKYGIIDAAAFLLERVGDVGTALSLILSGLNDKFVMLDMAV
GSKISDMDVGKHASMENFAAASELKEAADIKKILHACIGICQRNSPRLDPEESESLWFHL
LDSFCKLYLYLQSTLKIIYQLSLQAMKVTQKSMPSHGGFIRLRKVLPF
>Sgl16166 E3_activity/RING/RING 12.2 10.4
MIGYVRLPSIMAKLLSDNGSQEFGDFKLTILGMLGTYSFELKILDTAKCLIEDDTFYTMS
LLKKGASKGYAPRSLQCCICNCTFKTSSSSGIRLFNCGHASHLQCDVQENTSTQSFSGGC
PICVQKKKIHKAKGKMVEQGLVGASPSSSQRAQGTSILHPHEFDAFENSTTPQISRFEIL
SSLQKNQRLIPTDTMPQLRLAPPAVYHEKVNKRTHFPSGASREGQVDAEKPSRNKQLRDV
KVKGSQIRFPLKSKIFGKEKTRVI
>Sgl16224 E3_adaptor/Cullin_RING/DCX/DWD 21.3 0.8
MGSLSEEDDRYFDSKDYITPVDSGSDGVENSDSESRCVEDVVRNFGYDVWIRSPGTIGER
RQKLLKLMGIGSNQGVEESEYADSSSSFEGEVVDNARILENSGTVLRSSFKDLCSSSHSS
VSWCSNDTQELLDIALEENLVRRIKNLDDGSEFIVDELGQDGLFRRLREVGSNRTLSGEE
FEKILGLSPLVQRAMRRDVGWAQKNVAEGKRRTKKGWLRKLGVVACVADTQSGINRVDSL
PIQRRRAHNVRVRTCRKRSKEFSGLYMGQDIVGHEGAILTMKFSPDGQLLASAGEDGIVR
IWQVIESEKSEIVHVPDVTGSHVYFTVNQFGELVPLNVGKEKRGKLKSLRKSTESACVIF
PQKVFQLEEKPLHEFHGHHGEVLDLSWSLYLPCILHLYQYTTSTI
>Sgl16225 E3_adaptor/Cullin_RING/DCX/DWD 92 13.1
MRRDVGWAQKNVAEGKRRTKKGWLRKLGVVACVADTQSGINRGQDIVGHEGAILTMKFSP
DGQLLASAGEDGIVRIWQVIEPEKSEIVHVPDVTGSHVYFTVNQFGELVPLNVGKEKRGK
LKSLRKSTESACVIFPQKVFQLEEKPLHEFHGHHGEVLDLSWSNNKCLLSSSVDRTVRLW
KVGFDDCLKVFSHNDFVTCIQFNPIDENYFISGSVDGKVRLWSIPGFRVVDWTDLREIVT
AVCYQPNGKGAVAGSISGDCYFFDTSENRLQLTNQTSIHSKKKAPLRRITGFEFSPGDPN
KLMVTTADSQVRILKGIEVICKYKGLRNAGSQISASFTSDGKHIVSASEDSFVYVWDCTN
SDRAISSHFRSKSSCERFFSNNASVAVPWHGTTCGNVLPSLSGSSTNYSGIMVRYTTESG
FEHHRTSTDSPQLRTSLFSTDAISLGFSDPFSRGIATWPEEKLTNSNSLTVSSDTSKSEY
KFLKTTCQNMAGSTHAWGLVIVSAGWDGRIRVFQNYGLPVRL
>Sgl16227 E3_adaptor/Cullin_RING/Cullin 468.2 2.5
MMAIGLKSPKILPALMEKHDEYMLIELVKRWSNHKVMVRWLSRFFHYLDRYFITRRSLPS
LNDVGVHCFRDLVYQEIHGKVKDAVLALIHVEREGGHIDRALLKNVLGIYVEIGMGLMDQ
YEKDFEQHMLDDTAAYYSRKASSWIVEDSCPEYMLKSEECLRKEKERVAHYLHASSEEKL
LEKVQNELLLVFENQLLEKENSGCRVLLKDDKVDDLTRMFRLYSKVPHGLEPIGSIFKQH
MTEEGTALVQQAEDAAISKAENAGGGSHEQVFVRKVIELHDKFMVYVIDCFSSHTIFHKA
LKEAFEVFLNKGVAGSSSAELLATFCDNILKKGGSEKLSDEAIEDSLEKVVKLLAYVSDK
DMFAEFYRKKLSRRLLFDKSANDDHERSILTKLKQQCGAQFTSKMEGMVTDLTLGRENQT
HFEEYLGQNPNANPGLDLTVTVLTTGFWPSYKSSDLNLPSEMVRCVEVFKEFYQTKTKHR
KLSWVYSLGTCNINGKFGPKTIELIVGTYQAAALLLFNTADSLSYTEIAGQLNLADEDLM
RVLQSLSCAKYKILLKEPSTRTISQTDHFSFNSGFTDRMRRIRIPLPPMDERKKIVEDVD
KDRRYAIDASIVRIMKSRKVLGYQQLITECVEQLSRMFKPDFKAIKKRIEDLITRDYIER
DKENPQLFKYLA
>Sgl16234 E3_adaptor/Cullin_RING/DCX/DWD 46.9 23.6
MATPSSSSSSSSSVDLTDHLPLQLLKSETIPPSPNHSNSIDWLPDFAGYSWVAYGASSLL
VISHFPSPLSPHQSHIGPIFRQVFQLLPSYDVVSVVWSPVMPSSGDLAVASHNRIFLYHY
DSSPGSFCWSQTTLLVQSIEVEVITWTGSGDGIISGGSEVILWKRSGKSWEIAWKFRTKV
PQTLVSTTWSLEGPSASGACANKINAKELATVPCNSNDHVSVFQYDGKCGYVATELRHPQ
PVLAMQWRPCGERQLNRDVLYAPRNVLLTSCLDGVVRLWGEIDGSKMRKGNKDNREMSTS
RRSFCVVAVIEINQSFGGILGKDIFLQWALDMEGIICVRDGVNEVFNAGRSQTDEVGSCE
WLIGAGPGRMLTFWAVHCLDDISTMRSPRVTLWKSQEVMKPDLGSSSKNNGLRNSEGSYF
NKVVVWRNRRFGPPSVCSLIQLFPCNNLIWSVLYAQSLQKEYGESSNLCEMDSKLSCQSR
GVLDTLGHTGKVLQVAVHPSLHEVKLAVSLDSNGLLIFWSIFTSSNSFSGLPSLTPLWQL
RGKFILQNTVAQDMSLCWAPSWLEEEQILLIGYAQGIDCFIIKTCVTEENKILCHKFCTI
PFNKRDHFYGPDQVVSLPLPSCCKKDSNFNYYLLLGIWMKNFQAESWKVTLHSYELSESE
HSYESDTGSNGEYGVFKSKTDFAGKTYCMVASPCSTYIPDGLDEVTSFSVVSPRLSMYSL
QPKLVNDFCPSNFPYHMATGHSDGRSRIWRINLSDLSVGSTLFELVGIFSSLQCPITAIS
IADWGQKIATVCSDDINNVNMLYIWEPLHLAGAGTLVLEDKISLSGKVVAFNWFLMDNIL
FLGVCFQNELHIYSQRIRGAQTSLYLDKMQKESIWVCIGVVHTSSTICDFALGPRCTLIV
IHEKYFTLYSHWSLLTSDKHLTDGQLSADDAFDFKSQMDRNIPALSASKIQIFEELSVER
SSEDITIGSPLTKAHGDNIDTKPLIASPKKNHFSKMTVLAEILRGPLPFYHPEALLNNIY
SGNWARAYAAVCHLVQCLTPNTTANQSETPPISSLKLSKYFEGKLSNGEARGVQWSNDLD
TSTWSPPSEGGKMQFVESANNAINRMPTATAVSFGSYEFDEFLGKAQVRQAVTNAQKMQM
FAIVDLLYEISNIESTSAYESLDDPGKRFWCAIRLQQLEFRKRYSRAPSIAELVVNSRLF
VWAFHSDCQAILFSTILPAEPAWEDMRKLGVGFWFTNMTDLRSKMEKLARCQYLKNKDPK
ACALLYIALNRLQVLAGLFKISKNEKDKPLVAFLSRNFQEEKHRAAASKNAYVLMGKHQY
ELAIAFFLLGGDIISAITVCAKTLGDEQLAVVICRLIEGEGGASERHLISNILLPAAIEK
GDYWLASVLEWKLGSCLQSFLIVLGLQRDSYANESEINHAAFFDPSIGQYCQMLGAKNSL
RNAVGELNAAFLCRWTTMMTASAFNKCGLPLEALECLSSSVSIAGVLDKKQNGEDSEVLP
RILRPSLANSSRWLADEVACHLVSHVKLDLAMQYAVKLIKEHQCGLKTNVVLSRAGATAT
SWNSLEHEISQYGALLKNFKQELDSELAYLETKFSVVRDILLDKIFISLDNDGLLLKSYH
GSVSEVHSPASKNSDFTSFQLHHFENVTAYLSYSLPRFVVACIIARGWALASSELKWPVF
KPYWGFQSLEFYIPGFESSVLSLRTALMALSDDNSRNLVEQCFFALDLCKYCVYFALAML
QHNLKALDAMLQPVLVLCADGNYGEIDIISLREILNAVEAFSLKSSEINDLLGTQELLQE
NEGDMVFMTPEDEKWLVFRLCLWQHLSKFIKYQLNHLSSKLSCDATETSVVRSSVFPTPE
GKCSMNNVRQVLMNFIKTIGNTFTHVTSHTARQLAIFLWQKVEDGTSMPILTWLEEFSQS
TPSVFNDHQDQSCGTSEILDKETGFSCSKLLAKISHHPKLISEMLVQSPVKLSEVVHYKI
VKGWNHLHMCVLAEHEKLESYKQEGIFDNSPRGNKGKIHVGSEQNHNLLGPDFDGAALTK
KVVRFNNPKEIYRRSGELFEAFCINPIEQQQAALASNKKGISFFSWGDGLPSTDLSDYIW
QQSDWPQNGWAGTESTPVPTCVSPGVGLGSDKGSQLGLGGTTVGVGFQSKIGKDLTGGRA
FGIPGYAGIGSTGLSWGIQDEFDKCVDPPATLNNVNGSALAAHPSRPFFLVGSSNTHIYL
WEFGKEKAVATYGVLPAANIPPPYALASVTGLQFDRCGHRFASSASDGTVSAWQLEVGGR
SNVKPTESSLCFSGHVSDVCYVATSGSIIAAAGYSSTGVNVVIWDTLAPPSSSRASVMCH
EGGASSIAVFDNDMGTGSISPLIVTGGKSGDVGLHDFRYIATGKTKRHRHLNSVDRVMDT
AAIDIRSELSSSVGDQNRHGMLWYIPKAHSGCVTKIATIPNTSFFLTGSKDGDVKLWDAK
KASLVFHWPKLHERHTFLNRSSQGFGGVTRVGLTDIQVISDGFLTCGGDGTVKLVQLNNF
PS
>Sgl16257 ULD/UDP/UBQ/UBQ_PIM 85.9 0.1
MSSAGIAVSRIRAEEPLVSPRFFHNALDLNLAESIVVFLSVSGNMIPLRVFGSDSIESVK
LKIQCFKGFVAKSQKLVCGGRELSRSNSLVRDYGVANGNVLHLVIRLSDLQTVKVKTTCG
KELTFDVGRYRDVGYLKKQIAQRADEFDDVDDQELVYEGKPLNDQQLVDDICKNFDPVLH
LLVRKPFKFRVQRVEKNLDEWSLEAPELGRNREYDESADESVLVSSNVCEKDFILEPVVA
NPKAEIPSAILDVMERTCEGLESGNAPIRSNEGSGGVYFMQDSTGLEHVSVFKPVDEEPK
AMNNPHGLPLTSDGEGLKRGTIVGQGALREVAAYLLDHPSSGRRGVTGEVMGFAGVPPTG
LVSCLHQGFNHSNEVTHKMGSLQKFVKNDGSCEDIGPGSFPVEEVHKISVLDIRLANADR
HAGNILFRKDNETGQTVLIPIDHGYCLPECFEDCTFEWLYWPQARQPYSAETVEYIRSLD
AEEDIALLNFYGWDLPIQSARTLRISTMLLKKGVERGLTPYEIGSIMCRENIKVESVIEE
IVQEATDSVLPCSSEAAFLETVSQIMDRRLDEFSG
>Sgl16268 E3_adaptor/Cullin_RING/SCF/F-box 14 0.1
MRKRLKRNNVICSCNSPRSSFLSLRTSFCWYEDDVWFEIAKYLEGKSLVMLATTCKWFYK
TLSEECVWKFACLRDLGVLDPGNVSFKWKDLYASAFDGSHSYLFRQQEKHIDWIRIGAFS
LESSAAILTEKLTCPPRRIPQKETLEEMLQTCGFCVLTNIKTGIWIADLQLVRCPVCDLD
TCDGTMQTLDARHFELFMTGGYQDGSWDYTQIGVHETKKHVDGAAGAIFDMKHLKDSSTA
EIFNSKSWIGKKNDWQPKAKLTLHAVAVNTNLQDNEGINVKFHVMRAGTDGQIVAIRVSQ
QLL
>Sgl16269 E3_activity/RING/RING 31.3 12.0
MGFQTFSPFLTFLLSFILSSSAYSFCPTTTCKNDTLLPIRFPFHLEEQQPDNCSYPGFNL
HCSNQGRTVITLPHAGDFLVRHINYETQHILIDAENSCLPQKLLEGFDPSGTPFQADFYF
NYTFFSCPKHFSNGRSDVIDCLSNSTRSVFAVSATDVSAEMTESCQVIRSLLLPAISSEN
GGSPSSLSDDVWLSWFLPDCKECESRGGICGFHSNGNQQIGCFTDLRHSGDPAQTENSTG
LKIFRIIAFSIAIPAITCAVGVGIFLCIMDRRDRRSGAQVNRELQEVSATGQPLDTAMGL
DQATIDSYTKVVLGESRRVPGVNDGSCPICLSEYSAKETLRCIPDCKHCFHADCIDEWLK
LKGTCPLCRTSPADHAEV
>Sgl16270 ULD/UDP/UBQ/UBQ_Other 24.2 0.2
MAESNFIQFFVKIFDNKTLTLQFPSHQTLTPQSIKHQIESLTKIPIDSQNLTLNGKNLTN
STQITPKSLSFSTINLNFSLLGGKGGFGSLLRGAATKAGQKKTNNFDACRDMSGRRLRHV
NAEKRMEEWRAEEEERKMEKMAEEYLKKMEKKGKGGKKDEGAEKYVEKYRQQSRRCVEEV
ERSVRESVGQLMSDRKKKRKLEKSKGGSENVDAKKLKIWMGKRKVGESDSDDSDSDRESD
DSDAENEKSVVTENGNQSDSSKDASSVSISDLPLERENHSGGSSDSGSEVEKEMVNGGST
RLSATRSGSNGEVNGGSPVQTSSGEKMSASTEVLSTSAKTLVEQTPREYDSLASMISEQL
LSTTTSVEPESHQLPTVDPELDQAPECKAVSSNEGVTGSSNASEALQPLTFDNINSATEL
EVLGMERLKSELQARGLKCGGTLQERAARLFLLKTTPLEKLPKKLLAKK
>Sgl16295 ULD/UDP/UBQ/UBQ_Other 23.6 0.1
MIFDVGRYRDVGYLKKQIAQRADEFDDVDDQELVYEGKPLNDQQLVDDICKNFDPVLHLL
VRKPFKFRVQRVEKNLDEWSLEAPELGRNLEYDESADESVLVSSNVCEKDFILEPVVANP
KAEIPSAILDVMERTCEGLESGNAPIRSNEGSGGVTLCRIRQDWNTYRVEEGHNSWARGV
TGGSSLPFGSSIEWRRGVTGEVMGFAGVPPTGLVSCLHQGFNHSNEVTHKMGSLQKFVKN
DGSCEDIGPGSFPVEEVHKISVLDIRLANADRHAGNILFRKDNETGQTVLIPIDHGYCLP
ECFEDCTFEWLYWPQARQPYSAETVEYIRSLDAEEDIALLNFYGWDLPIQSARTLRISTM
LLKKGVERGLTPYEIGSIMCRENIKVESVIEEISKKLQTRCSRAQVKRLS
>Sgl16315 E3_adaptor/Cullin_RING/Cullin 502.5 7.0
MNDRKVIELQQGWEFMEKGITKLKKILEGLPEPPFNSEDYMMLYTTIYNMCTQKPPHDYS
QQLYDNYKQAFVDYINSTVLPSLREKHDEFMLRELVKRWSNHKVMVRWLSRFFHYLDRYF
IARRSLPSLHEVGLTCFRDLVYQEISCKAKDAVIALIDVEREGGQIDRGLLKNVLDIYVE
IGMGQMDHYEKDFEVHMLDDTAAYYSRKASSWILEDSCPEYMLKSEECLKKEKDRVAHYL
HSSSEPKLLEKVQNELLLVYENQLLEKENSGCRALLKDDKVDDLSRMYRLYSKVTKGLEP
IGSIFKQHITDEGTALVQQAEDAAISKAENAGGSHEQVFVRKVIELHDKFMTYVTECFNS
HTIFHKALKEAFEVFLNKGVAGSSSAELLATFCDNILKKGGSEKLSDEAIEDSLEKVVKL
LAYVSDKDLFAEFYRKKLSRRLLFDKSANDDHERSILTKLKQQCGGQFTSKMEGMVTDLT
LARENQTNFEEYLGQNPDANPGLDLTVTVLTTGFWPSYKSSDLNLPAEMVRCVEVFKQFY
QTKTKHRKLTWVYSLGSCNINGKFGQKTIELVVGTYQAAALMLFNTSDRLSYSEIAIQLN
LADEDLVRVLQSLSCAKYKILLKEPSSRTVSPTDYFSFNASFTDRMRRIRIPLPPMDERK
KVVEDVDKDRRYAIDASIVRIMKSRKVLGYQQLITECVEQLSRMFKPDFKAIKKRIEDLI
TRDYIERDKENPQLFRYLA
>Sgl16316 ULD/UDP/UBQ/UBQ_PIM 442.9 23.2
MQIFVKTLTGKTITLEVETSDTIENVKTKIQDKEGIPPDQQRLIFAGKQLEDGRTLADYN
IQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVETSDTIENVKTKIQDKEGIAPDQQRLI
FAGKQLEDGRTLADYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVETSDTIENVKT
KIQDKEGIPPDQQRLIFAGKQLEDGRTLADYNIQKESTLHLVLRLRGGMQIFVKTLTGKT
ITLEVETSDTIDNVKSKIQDKEGIPPDQQRLIFAGKQLEEGRTLADYNIQKESTLHLVLR
LRGGMQIFVKTLTGKTITLEVESSDTIENVKTKIQDKEGIPPDQQRIIFAGKQLEDGRTL
ADYNIQKESTLHLVLRLRGGDA
>Sgl16317 ULD/UDP/UBQ/UBQ_PIM 98.6 0.8
MSGQIYVETVTGETIRLDEESLDIVKAKVRNKEGIPQEHQRLVFPANRQININSGRSHDD
TNRVMQIFVKTLTGKTITIEVKSSDTVFLVKARIWKKTGMPVEEQRLIFNGKQLEDERTL
ADYKVCKEATFHLVIRLRGA
>Sgl16337 E3_adaptor/Cullin_RING/DCX/DWD 89.9 12.2
MPGNNNVQEIKMGGSELPSKQEDFPKMASPVIYDLMRGQLHGTSGHNCTDELENNSLEHC
GITFSGLEPPCVSTQSPEHAGRMVKTFKMEKHKDHGLDVSNKDVHLRKGHWPHFYQMVGG
PKHTDFQGDPPSRVNDKLTINVGEDSKRSDIDAWNLRHLITKQDETGRVSVDAMHGKNMN
CESALLPQDARLKILSTSSFSQYFGKKTAKGKGVVSGQLGDKADFDSAGNLESNTRMFSN
ASMASDFCGRTLSQSVVNLREWLKPGNCVKDKVVSLNFFRQIVELVNLAHSQGAILEQLR
PSYFNIMSSNKLKYIGSSTQIDLPVPKSLTGCKKRSPEEDINVLCTSDVKQQRVLNHPSS
VTSKTRVSSAMHHELKCDAGSSSGSYNFANGSLSMPSCQATRLEKSPLTELHLEEKWYAC
PEELDARASKLSSNIYSLGVLLFELLCSFESLETHSSAMFDMHHRILPPFFLSENPKEAG
FCLWLIHPIPSSRPTIRDILLSDLLCGSHELKPSSESALSTNDFDSSESELLLDFLVSVK
DKKQDCAMKLVEDIRCIETDIKGLHGKSSLLTSQVHVKKDYNLQDFIKSIAKSGRNGDRL
KNDMSQLEKAYFLMRGQASATTGASRADRDLLKKREIWSQVQSQNDIVSKNQKSASGLDK
FFEGLCKFTCYSKLELRGTLRNGDLLNSNNVICSLSFDRDEEYVAVAGASKKIKIFEYSA
LVNDAIDIHYPVIEIGNKSKLSCISWNSYIRNYLASTDYDGAVQVWDASTGMGYSHHTEH
QKRAWSIDFSRADPTKFASGSDDCSVKLWSTNEKKSTCTIWSPANVCSVQFSPYSSHLLM
FGSADHKIYGYDLRHMRIPWCTLSGHEKTVSYVKFTDSETLVSASTDNTLKLWDLSKTSL
SGMSSDACHTTFSGHTNKKHFVGLSVSDGYIACGSESNEVFTYYRSLPMPITSYKLSSIH
PVSQQDVREDDGLFVSSVCWRSKSNTILAANSGGSVRLLQLV
>Sgl16348 E3_adaptor/Cullin_RING/Cullin 501.2 7.1
MNDRKVIELQQGWEFMEKGITKLKKILEGLPEPPFNSEDYMMLYTTIYNMCTQKPPHDYS
QQLYDNYKQAFVDYINSTVLPSLREKHDEFMLRELVKRWSNHKVMVRWLSRFFHYLDRYF
IARRSLPSLHEVGLTCFRDLVYQEISCKAKDAVIALIDVEREGGQIDRGLLKNVLDIYVE
IGMGQMDHYEKDFEVHMLDDTAAYYSRKASSWILEDSCPEYMLKSEECLKKEKDRVAHYL
HSSSEPKLLEKVQNELLLVYENQLLEKENSGCRALLKDDKVDDLSRMYRLYSKVTKGLEP
IGSIFKQHITDEGTALVQQAEDAAISKAENAGGSHEQVFVRKVIELHDKFMTYVTECFNS
HTIFHKSLKEAFEVFLNKGVAGSSSAELLATFCDNILKKGGSEKLSDEAIEDSLEKVVKL
LAYVSDKDLFAEFYRKKLSRRLLFDKSANDDHERSILTKLKQQCGGQFTSKMEGMVTDLT
LARENQTNFEEYLGQNPDANPGLDLTVTVLTTGFWPSYKSSDLNLPAEMVRCVEVFKQFY
QTKTKHRKLTWVYSLGSCNINGKFGQKTIELVVGTYQAAALMLFNTSDRLSYSEIAIQLN
LADEDLVRVLQSLSCAKYKILLKEPSSRTVSPTDYFSFNASFTDRMRRIRIPLPPMDERK
KVVEDVDKDRRYAIDASIVRIMKSRKVLGYQQLITECVEQLSRMFKPDFKAIKKRIEDLI
TRDYIERDKENPQLFRYLA
>Sgl16349 ULD/UDP/UBQ/UBQ_PIM 529.6 29.4
MQIFVKTLTGKTITLEVETSDTIENVKTKIQDKEGIPPDQQRLIFAGKQLEDGRTLADYN
IQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVETSDTIENVKTKIQDKEGIAPDQQRLI
FAGKQLEDGRTLADYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVETSDTIENVKT
KIQDKEGIPPDQQRLIFAGKQLEDGRTLADYNIQKESTLHLVLRLRGGMQIFVKTLTGKT
ITLEVETSDTIENVKTKIQDKEGIPPDQQRLIFAGKQLEDGRTLADYNIQKESTLHLVLR
LRGGMQIFVKTLTGKTITLEVETSDTIDNVKSKIQDKEGIPPDQQRLIFAGKQLEEGRTL
ADYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVESSDTIENVKTKIQDKEGIPPDQ
QRIIFAGKQLEDGRTLADYNIQKESTLHLVLRLRGGDA
>Sgl16350 ULD/UDP/UBQ/UBQ_PIM 98.6 0.8
MSGQIYVETVTGETIRLDEESLDIVKAKVRNKEGIPQEHQRLVFPANRQININSGRSHDD
TNRVMQIFVKTLTGKTITIEVKSSDTVFLVKARIWKKTGMPVEEQRLIFNGKQLEDERTL
ADYKVCKEATFHLVIRLRGA
>Sgl16365 E3_adaptor/Cullin_RING/DCX/DWD 89.9 12.2
MPGNNNVQEIKMGGSELPSKQEDFPKMASPVIYDLMRGQLHGTSGHNCTDELENNSLEHC
GITFSGLEPPCVSTQSPEHAGRMVKTFKMEKHKDHGLDVSNKDVHLRKGHWPHFYQMVGG
PKHTDFQGDPPSRVNDKLTINVGEDSKRSDIDAWNLRHLITKQDETGRVSVDAMHGKNMN
CESALLPQDARLKILSTSSFSQYFGKKTAKGKGVVSGQLGDKADFDSAGNLESNTRMFSN
ASMASDFCGRTLSQSVVNLREWLKPGNCVKDKVVSLNFFRQIVELVNLAHSQGAILEQLR
PSYFNIMSSNKLKYIGSSTQIDLPVPKSLSGCKKRSPEEDINVFCTSDVKQQRVRNHPSS
VMSKTRVSSAMHHELKCDAGSSSGSYNFANGSLSMPSCQATRLEKSPLTELHLEEKWYAC
PEELDARASKLSSNIYSLGVLLFELLCSFESLETHSSAMFDMHHRILPPFFLSENPKEAG
FCLWLIHPIPSSRPTIRDILLSDLLCGSHELKPSSESALSTNDFDSSESELLLDFLVSVK
DKKQDCAMKLVEDIRCIETDIKGLHGKSSLLTSQVHVKKDYNLQDFIKSIAKSGRNGDRL
KNDMSQLEKAYFLMRGQASATTGASRADRDLLKKREIWSQVQSQNDIVSKNQKSASGLDK
FFEGLCKFTCYSKLELRGTLRNGDLLNSNNVICSLSFDRDEEYVAVAGASKKIKIFEYSA
LVNDAIDIHYPVIEIGNKSKLSCISWNSYIRNYLASTDYDGAVQVWDASTGMGYSHHTEH
QKRAWSIDFSRADPTKFASGSDDCSVKLWSTNEKKSTCTIWSPANVCSVQFSPYSSHLLM
FGSADHKIYGYDLRHMRIPWCTLSGHEKTVSYVKFTDSETLVSASTDNTLKLWDLSKTSL
SGMSSDACHTTFSGHTNKKHFVGLSVSDGYIACGSESNEVFTYYRSLPMPITSYKLSSIH
PVSQQDVREDDGLFVSSVCWRSKSNTILAANSGGSVRLLQLV
>Sgl16373 UBD/UBC-like/UBD_UBC 247.8 0.0
MASKRILKELKDLQKDPPTSCSAGPVAEDMFHWQATIMGPTESPYTGGVFLVTIHFPPDY
PFKPPKVAFRTKVFHPNINSNGSICLDILKEQWSPALTISKVLLSICSLLTDPNPDDPLV
PEIAHMYKTDRSKYETTARSWTQKYAMG
>Sgl16387 UBD/UBC-like/UBD_UBC 294.5 1.4
MGSSEDVKSAKAEKSSPPPTEQSGVHVYPDWAAMQAYYGPRVALPPYFNSAVAPGHPPPP
YMWGPPQAMVPPYGTPYAAMYPPGVYAHPAVPLGSQAHGQGVASPAVTEPLVATPLSMDT
PAKSPKKSDSGLIKKLKGFDGLAMSIGNGNSEKPEGETENRLSSQSAETEGSSNGSAGST
DKDDENKRKRSREGTPTSVEDDKTKLKPVLPPADKVLGVSITPANGAAVSSGVATTLELK
NPGVSVKCNSSSVSPPNAVVSSEPWLQNERELKRERRKQSNRESARRSRLRKQAETEELA
KRVESLNAENMALKVSFLLLPMASKRILKELKDLQKDPPTSCSAGPVAEDMFHWQATIMG
PTESPYTGGVFLVTIHFPPDYPFKPPKDKSFPTINSNGSICLDILKEQWSPALTISKVLL
SICSLLTDPNPDDPLVPEIAHMYKTDRSKYETTARSWTQKRVDGHLLHGNRKGLNLPVAV
FDSRLINDVLVAFRTKVFHPNINSNGSICLDILKEQWSPALTISKVLLSICSLLTDPNLM
TPCARDRPHVQD
>Sgl16396 E3_adaptor/Cullin_RING/BCR/BTB 34.1 0.0
MRNMNRDLFDPRSVMDSEIDRSPKEGNFGFAFNDSNFSDRVLRIEIMAGPSDSKLDDACC
SLLDWARNRKRRREDLKKDVSNDINVNNNNNTNIDGTEVAVCPEEQVLNQSDGDDLLGCD
NDDEEAVAMVEEIPSGDDGENSNDSSWSMECSTVVRVQTLHISSPILAAKSPFFYKLFSN
GMRESEQRHVTLRINASEEAALMELLNFMYSNTLSGNTAPALLDVLMAADKFEVASCMRY
CSRLLRNMPMTPESALLYLDLPSSVLMAEAVQPLTDAAKQYLADRYKDITKFHEEVMSLP
IAGIEAILASDDLQVASEDAVYDFVLKWARSQFPKLEERRDILASRLARYIRFPYMTCRK
LRKVLSCPDFDHEASSKLVLEALFFKSEVPHRQRILAAEESASTNRRFLERAYKYRPVKV
VEFDTPRQQCVVYLDLKREECANLFPSGRVYSQAFHLGGQGFFLSAHCNMDQQSSFHCFG
LFLGMQEKGSVTFAVDYEFAARSKPTEEFQSKYKGNYTFMGGKAVGYRNLFGIPWTSFMA
EDSLYFINGILHLRAELTIRH
>Sgl16401 E3_adaptor/Cullin_RING/SCF/F-box 22.4 0.0
MDGDTWASHYQYRYVINPAKFDSFSDVTDEENKDIVSVDSALPDDLLERILAYLPVASIF
RAGCVCKRWNDIVSSKRFLWNFSANILSHKPWYFMFTSTDDSFGHSYDPALKKWYGIELP
YYVTSNWFIASSFGLICLMNNDNSTEVHVYNPITKCNKMLIEPSGLKSSDYSALAISVDK
LSHNYNVSIVKSKQVPDNFYQWDLSIHVYNSGTMMWVTTLTEVLNGWRAGDESVICGNAL
YFLLYSTGGGTPDNRHGLIKYNLSSQSSQGKLMRNFIPAPCSLTCGRLMNLKEKLVMVGG
IGKQDRSDIIKGIGIWVLNGTEWQEVARMPHKYFQGFGEFDDVFASSGTDDLIYIQSYGA
PALLLFDINYKQWRWSQKCPVTKRFPLQLFTGFCYEPRLEVSP
>Sgl16417 E3_activity/RING/RING 33.3 9.0
MSSTTTPPPPLSSHFSLSLQNLGLGYAIALAFGFLVLFSALLLSSYLCCRRRHHHHNRNH
RHHSSADSNTIIVPRIFFVAEDDDDDLENNHNSSSSNGVVGLDRAVINSYPKFHFYKKNL
ESYTSSMTDNLMMCSICLCDYKDGEMLRMMPDCKHFFHLTCLDAWLKLNGSCPVCRNSPL
PTPVSTPLAEVVPLSHYPDNRRSSTVVSSSS
>Sgl16426 E3_activity/RING/RING 33.3 7.6
MVAQNTFSKTICSICYEDLKPIVEDLQAISICGHVFHELCLQQWFGYCTNTKKQSCPVCK
QGCKDKDVGRLYFQSIGDPALSQSQTEVQKLSQNRDDESPELLRFEVKRLEVKVSGLNSA
LDLRQKDLKQVNDELQICKEQLSKEIVLKNEALSQRQCIQAMLQTKSNDLAKSNLECSKL
KERNLALVKEIAALKLVSDCNLEEEEIVKLATVGNESNSQDAIDVLKKSLVIRNKSYKEL
MAKCNSLGRGEARSLKKLEKAKDKIVKLKTRVQELETTIEEKENEVLRSLKASKKRNCDD
VNLPSVHMQTNPLSVFKNSPVEDKGQSPTSVIDLDDEGNDEHLVVKENKKDATVGFKSDS
RTFQHKETRDYDCLIDDGDEPQKLRTGNPHSKADDNKEGSSKKYKSFVSVDFDDKVDLVQ
QSNHQCGLSGFRNEVPVDHSATKEASGLVLQDIRQVQPSFMSTAETPASIPLAEPGNRCF
SGGLLGPDGANRYLGKWCKRTQNKSPLGSNSDADALITVGADGRGGRVKVLRSPNQISMD
AKDSMVSAKRFKAGAKSSGLQSQGCRQIDHFFRKANN
>Sgl16449 E3_activity/RING/RING 34.3 6.1
MGFPVGYTEVFIPTLFLHTLTFFTFIRKFLFNFFQYFGLSDFLEPGPMAPIEPLPARITS
TPSPSLGPPPLSAILTRELLPLVHVSKEQEENESCAVCLYEFVSGEEIRWLGNCKHIFHK
DCLDRWMDLDHRTCPLCRTPFLLDDLLDQFNQRFLAADADDSCDLLQYVDHFNYTGF
>Sgl16456 E3_activity/RING/RING 35.8 5.3
MGGCCCSSRKSQLQGTPVYYYCPPTLEGQENLRACRGTASGLSTGLLVGPNLDTSSPDTF
RPPPAPIPFNVLFGRPQTPLRALGSLGPKCDAVKESKPSSIGVNTGADGSDLLIPVDRVG
KSEGRTLADILLASPTKSDVEISKPTEAYELAPEDEDACPICFEEYDSDNPKMVTNCDHD
FHLSCLLEWMERSDSCPVCDKEMIFDHPDDQN
>Sgl16460 UBD/UBC-like/UBD_UBC 107.8 0.0
MSSPSKRREMDLMKLMMSDYKVEMINDGMQEFYVEFHGPNESPYHGGVWRIRVELPDAYP
YKSPSIGFINKIYHPNVDEMSGSVCLDVINQTWSPMFDLVNVFEVFLPQLLLYPNPSDPL
NGEAAALMMRDRAAYDQRVKEYCEKYAKAEDAGAVPEEKSSDEELSEDEYASSDEAMVGQ
ADP
>Sgl16474 E3_activity/RING/U-box 89.1 0.0
MDLIILEDGNTSDIETGFKKLMKEDKLYVAVGKDVKENESLLSWAIQNSGGRIISIIHVH
QPDYFIPILGEKFHWSSLKEQQVTAYRGIEKQFMHKNLDEYLHYCRQFGVQAEKLYIEMD
SIEKGILQLIAEHNVEKLVMGAAADDCYYNKMTEVMSKKADYVQLHAPTKCHIWFICKGH
LIHQRKCSPQTKIHTQEMSIDSNSLSLMDQSTNRCAVRHEEVVLGDGSSSHFGSSNGRVV
RSPSTNDIETSNGFGPAVDLEANCHNWSEILQLLRSEVNEFSAGSSSHTSRELTAEQLEQ
LADLFFEQNHHCHTSAAQRKLLQSVQREAVKKSKEFEEDLEKVKNDRDKLREELQDAMEQ
NLILESKVSNYDQVVKQLEEGFISNVELLQVCENERDDLKIQRDNVLKTAEELLNLSAEA
SSKTEVLKFLTTFTFAEIKEATNDFDPALQIWEGENGSIYKGVVSCTQVTIKIWRPEGLQ
GPRAFHQEVEILSKFRHPNMVVLVGVCPEAWAVVYEYLPNGNLQERLNSTSDTNLSWKNR
IKIATELCSALVFLHSRSPRRVIHGALQPTSIFLDSDFTCKIGGFDFSHMIPQHEEEESH
SPSREPLHCSLYTDFEYCTTGVATPAMDVYSFGLILLELLTGKPAFGLRDELEDALDGDS
FVSLLDTSAGEWPFVQAKQLARLALRCCMENGSDRPDLESDVWRVLEPMRISSGGSTSYR
LGDGPDGHRQAPPYFLCPIFQEVMKDPHVAADGYTYEVEALRGWLDSGHNTSPMTNLTLE
HFNLVPNHSLRSAIQEWRQRH
>Sgl16475 E3_activity/RING/U-box 77.3 0.0
MEQIQQERIYVAVGEDAEESESALNWALKLSEGDTICVIHVVVPAQKFPQPSSASQTSSN
AVGKVDVKEFQEWPRKEVVELVDEWLKMCDLNQVPYENFYVEKEVITEGILELISQLGIR
KLVMGAGVNNKKLRIKRPTSRKSNYVLQFAPVSCYIWFVSKDRLIYSRNGMKQMNPNLEE
SSLYTPSAVSVQTLGEVERSRQETHEESETQKAFNKVKSTKKELKHVIKGLKKIQIKLHT
DSKKLLQEAGASSSLLERQVIDSILKGNETTEEKLNTKMLQKYKKRCEEVKLECDNAIEA
AQVLQKQVSEEPSSFPKFSCEFSQLDIQEATKCFHPSLKIVERESYSVYKGFLYYTEVAI
KTRKHDWCILNFDKEIDVLSKLRHPNLVTLIGTCPDSLSLIYEYLPNGNLEDRLSCKDNT
PPLPWATRIRIVTELCTVLNFLHSMKPCSIIHGQLNLRKILLDVNFRCKLGGFGLCHVIS
DDSSFLTGLLLEAGHLSTKSDVYSFGIILLQLLTGRPTLKVVEETQDALENDRLHSMLDT
SAGDWPIIRAKQLAYIALKCCDVNPKDRPELGSEVWSVLKPVITPSETLSSPLQLLTEDR
VPSHFLCPIFQEIMREPHFAADGFTYEGDGIRGWFEGGNDTSPMTNLKLDNLNLIPNRSL
RSAIQEFLLQHQRA
>Sgl16481 E3_activity/RING/U-box 87.6 0.0
MKKDLEFTNSLLEKVTQELHEASEQKLSLESQLEKTYLSEKELEKKILSAVDLLQKWKNY
QNELEEERDHALQEAEELRYQLAQHSQRSLRSNDSNFDFSFAELHEATNNFDSALIIEEG
EKGTTYKGVLHHIDVAITMLNPNTISGPREFEQEVYMLSKLRHPNIVTLIGICSDPLALV
FEYLSRGSLEDRLMRKDNTPPLPWKTRIEIAKQLCSILTFLHSRSPSSIIHGNLKPENIL
LNEKFVCKLHGFCLDLKFPGTEELTPAANVYSFGIILLRLLTGKLAFGLANDVKDALDSD
DLSVILDKSAGNLPNVQAKRLASMALRCCDMDPNVRPDLSSEVWNVLESIKASSQPLSRL
PLESEEEVPHHFICPISLDIMEDPRVAADGFTYEAKSIEEWLKNYKNSSPMTSEKVANKV
LIHNHALRSAIQDWLERCRSA
>Sgl16483 E3_activity/RING/U-box 92.9 0.0
MGSSRGFEGDARKIMVVDNKIFVAVCKELKESKSKLKWALENSNGKKICIIYVHVPAKVI
PMPMGGKFPVSQVGEKELQSFRKQENSEMLKNLDDYLQLCAQFGVRAEKIHITMDSIEEG
IVEIISQHKIGRLVMGAAADSRFSRRMVEPKSKKANYVCQHAPDFCHISFVCKGRLICTR
EGVRQPSLEVEGILSNSSSGDQLNASFLSQEFSGYDGSSDGFDKSSRISFSKSIHSAHSA
EADSVLSSPCSSISREEFREPGMELLALSPATNKRQDSSPPSVLQESSMNDDLYDQLVQA
TAEAESSRREAFDEAMRRQKAENEAMEAIRKAKAAERLYFKEIKLRKEKQEELEKRKEEL
EITKREWEKAMHELHEALDRKSLLETQYEKSKVSEKEMEEKILSAVDLLQKYRTEREELQ
VQRDHALQEAEKLRKQFAQEPSSSYVPFYFSEFSFSDLQKATNNFDPSLKIGEGGYGSIY
KGFLRHTEVAIKILNPNSMQGPNEFEQEVDVLSKLRHPNLVALIGACPESWALVYEYLSG
GSLEDRLVCKDNTPPLPWQTRIQIATELCSVLIFLHSSRPSSVIHGDLKPSNILLDDNFV
CKLGDFGICCVVSNSEQTTKFCTTQPKGTFTYMDPEMFTTGELTPKSDTYSFGVILLRLL
TGKPAMGIQKEVEYALDKGNLNCLLDPSAGDWPFVQAEQLARMALRCCHKTGKNRPELGS
DIWRVLEPMKASSRSLSMLRLASDDRAPHYFICPIFQELMEDPQIASDGFTYEAEAIRGW
LDSGHDTSPMTNAKLSNHDFVPNHTLRSAIQEWLQLHRSLTAIESTLLYEA
>Sgl16489 E3_adaptor/Cullin_RING/SCF/F-box 19.6 0.0
MATLPTEIITEILSRLPVNSLLRFKCVSKSWYSLIKNPIFIKLHLNQTLISNSDNFLLKW
NDFSSKIHLASLHFPHYHPFTFLELHHPLETQGFYFLGSCNGVICICNASKDDVVLFNPL
TRTQRKLPKDRIPLIFPSVSVFGFGYDSKSDDYKVLKIVQWFKLDQRFFKAQVYSVNNDS
WKSVEGIKHNLNLLYSDSHGVLINQALHYMVIEYGVALWSASASELLSKCKFIACFDLET
ETFSLIDCPNYDEELSASTSLKFHLMELGGYLSVCVNYRTSDHAHTLPPESADTGLSNHM
LFRADLWVMKVYGEKESWVRLFSICDVKSFRSVTCLKPVVYSKDGRSVLIVVDYMDVVWY
DLESKKVVRLESNGLQKESYDTVLFTGSLVSFQDKVHPKRSSLAMKNNKRQDLNNFLSTG
FKLKL
>Sgl16560 E3_activity/RING/RING 37.1 8.9
MSTNDADTTAPLLAPLSPTTGNQSFQSRSRRLSGRAGLRGAARFLRRTNSRRMMSEHSMT
VRESAAQQIEERQSDWAYSTPIVVLDLLWNTVFVLVSIVMMIISGDEKTEVPLRLWLIGY
GFQCILHMVCVCVEYKRRREVVRPRFGSSNGWGAGVVAAQGFGSSSNLNVNANPGSNRSS
YANSRSNSSSSASLEEDAMDFAAEAYQDDDNTSVAKHLESANTMFSFIWWIIGFYWVSSG
GPTLSDDAPKLYWLTITFLAFDVFFVVICVVVACIIGIAVCCCLPCIIAILYAVADQEGA
TREDIERLPKYKFRRLGQIEDKSGEIQGLGGIMTQCDTDTLIEHAISEEDSECVICLTSF
EDGSELRALPCRHNFHCACIDKWLQINATCPLCKYNILKNGNQSSEEV
>Sgl16567 E3_adaptor/Cullin_RING/SCF/F-box 16 0.0
MGAGISSACPNSGVKVDRKMEDIPESCIAMVLAHLDPLEICQLARLNRAFNGASSADFIW
EHKLPTTYSFIIDRITKGDDHGRGGGDEDYAKGSISSSSNSRSSNEFVGLTKKEIYARLS
RPYLFDSGTKEVWLDKSTGGVCLSISSKALSIIGINDRRHWNRIPTEESRFHTIAYLIQV
WWFEVCGELEFKFPAGEYSLFFRIQLGKTSKRFGRRTCNAEHIHGWSTKPARLQVTTADG
QHDFSDHYLENPGSWTLYRAGDFVVKDPNKLTKLKFSVRQIDCTHAKGCIMVSIYLVETQ
DGCFSRASLALLVVSSGQRKCSPMFWPEAPNNNGLMVTYTKNLVALQRQTYLQVYLSANA
SARRWEIVSFDFLSPRVLNFDFSTVGDSSKVLGAGNNLELCCFKVLLYSKMEHHWDIFES
LDPDVSSKILMSLDDPADIVRASSVSRAWRDFVIANGICKHLCLRLFPQLSGIITRVVDT
SSQQDKCSDVGCSQVAEMDHLKKEHRAFVSLVRGLTTSEVGECLSNAISASSTDNYPEEG
VHNTLESRDRIGRRASYWSSSGQSNPDVPERLTYKLISDLCIITEVNIQPFQAFFQADSP
IYSAKAVRFRMGHRKLPDGEKDLTLHEGQECAEEKYVWTYTSEEFPMVQENRLQNFKLRE
PVLCVGGFIRIELIGRVQRQEMDGLFYICVSHVEVMGRSMSPVFGVDTLDQNGRFALLFN
PHAQFSSPRSLNEEGDEITVTPEMVRRHVRGWEQILNMLRGTLGVEVYDSEDENPDSDDE
IAEEYAL
>Sgl16574 E3_activity/RING/RING 40.7 5.8
MMYDINLITTVIGFGMSSIFIVFVCTRLICKRLQLTDSRGAVDTEPETDVEQPEQRTRTD
GLEPVVVAAIPTMKFHQDAFSSGEDSQCSICLGEYEEKEVLRIMPKCGHSFHLSCIDPWL
MKQSTCPVCRLPLKHSYDPKLGWLDGHVEPPMENTSQLFLPDARNSADNFGNQQHHQSTT
SSSNQELDLHGVSEHRQGLT
>Sgl16622 UBD/UBC-like/UBD_UBC 115.7 0.0
MATNENLPPNVIKQLAKELKNLDETPPEGIKVGVNDDDFATIFADIDGPAGTPYENGVFR
MKLILSSDFPHSPPKGYFLTKIFHPNIANNGEICVNTLKKDWNPTLGLRHVLLVIRCLLI
EPFPESALNEQAGKMLLENYEEYAKLARLYTGIHAKPKSKLKYGAVSESTTALNVDNRNN
TSAQNADQKNNTLANTLAAPQSITASSKATSLHDQCASTTASTPSSNDNSRAVESSTAPS
VSVAPPAQKKDGVLKAQQAEKKKIDARKKSLKRL
>Sgl16625 E3_adaptor/Cullin_RING/DCX/DWD 29.2 6.6
MGTAWMECLQPVDTKSVYSKDFNALSYKFIAVLVASLALARNIQRSEIDRRTQVDMLTRH
RQATGSRAWRKLVHYLTEMNCLFGPFHDQLCNPERVFWKLDFMESSSRMKMFLRRRNYKG
SAHIGAAADYEDDAAAPHDQQREISASNASVLAVEAISADALNEDDENVVVNNRTSIDFD
VEQHAEHHSRHTVGAESQTQVSSHSHDAPTTSGQDLSEDPSAVAPGYVPSERDERIMLEL
PCSMVRPLRVVRGTFQITTKRINFIADYSEASSSGSELDHSLELRDQEKNRSWLISSLHQ
IYSRRYLLRRSALELFMLDRLNYFLILGEGRRNAYRAIVHARPPHLNNIYLATQRPDQLL
ERTQLMERWARREISNFEYLMQLNTLAGRSYNDITQYPIFPWILSDYTSQQLDLSNPSSY
RDLSKPVGALNPERLKKFQERYSTFDDPVIPKFHYGSHYSSAGTVLYYLVRLEPFTTLSI
QLQGGKFDHADRMFADIAATWEGVLEEMSDVKELVPELFYLPEMLSNANAIDFGTTQLGQ
KLDLVKLPPWAENPVDFIHKHRMALESDYVSSHLHEWIDLIFGYKQRGKEAIAANNVFFY
ITYEGTVDIDKISDPVQQRATQDQIAYFGQTPSQLLTVPHIKRMPLAEVLQLQIDNRYYF
GLYCVLDNISEPKELKPYAVPMPERLNLPASAMHASSDSVIIVDINAPAACVAQHKWQPN
TPDGKGAPFLFHHGKATTSTSGGGFMRMFKGPAGAVSEDWHFPLALAFPTSGIRSSAIVA
ITNNKEIITGGHVDNSIRIISADGAKTLETAIGHCAPVTCLSLSSDGNYLVTGSRDTTVL
LWRIHSISTNNSEPSTSTSTHTSNTGNASTSILVDKKRKRRIEGPIHVLRGHLAEVVSCC
VRGRLLRRIASVQAHSVCLSSDGILMAWNQTQHLLSTFTLNGIVVARVQLPSSGSISCME
ISFDGQTALIGYNCSEGEHSLDRSRSWNSKQQGLGSLSTVLDLKQEDSILDMVSPSICFL
DLYTLKVLHRLNLQAGQDITAIALNKDNTNLLVSTVDRQLIVFTDPALSVKVVDQMLKLE
TLGAYKLQLREERRWRESQKEREKNFLAAHGGNNRLPPPPKTSSIDALPSKLRRIMAFTS
PSSPTLQGSSLDSGNVAATNNRKNKKEGSTQIKPQSESEVNFKSNETRDKKASKSTVSQG
VSSSDANDDKKKKKRKRKQAGDDCGLKRSWKS
>Sgl16670 E3_adaptor/Cullin_RING/DCX/DWD 56.2 8.9
MNPLLPIILLTTILAAIIAFLIFGNYFKKQKSEVESLAKAQPNNNNNATSKKPSKSTVSS
KKSQFKHHSHASDKEQNKKHHPLDLNTLKGHGDLVGGLCFSSDGRNLVTACADGVVRVFR
LDDISNKSFKFLRINMPAGNHPVAVVFLEDDSSIVVATQTLSGSSLYMYAEDKANSSNGN
KQQAKLPLPEIKWEHHKVHQKNAILNLFGTTARYGSADGSTIIASCSEATEIKLWHGKTG
KLLGTVDTNQLKNHMASISPDGRFMAAAAFTADVKIWEIVYTKDGSVKEVVKAMQLKGHK
SAVTCLGFAPNSDKMITASKDGTLKVWNINVRYHMDEDPKILRGFPIPLQDSNGATLHYD
HLSVSPDGKILAVTHGSTLQWLCAETGKVLDTAEKAHDGDITWITWAPKSLPAGNSESFI
LGSSGVDKKVKLWMAPSIRPS
>Sgl16719 UBD/Alpha-Helix/UIM 13.3 0.1
MRKNPRTTKIEKVTLKEVSSDSEASENSISDEPNSPENEAIDYEKQRKLRIAENNARMEA
MGLQTIANSLMKLGGKRKKDVKNGKEDDEYEPTDDDDDDEVKDDDSDSSSSDECGKKKKM
KKKQKQKQKEKANATTSVSQRVEHPPGVFIPDSSLHAIGHCGEKIYLVFPKASKEKVKDL
VDRYPEGFNGFNREQGERALRRIADLKAECWKLRRSYMWWYPEFREEGVEGLPFPEGFNG
FNLEQSKEISRVLLTLENVYTRLKKCFQPNMHEVAKGVQRPEVAPGFYPMGTSYPPPTHA
SCPQQQASTFIPGPVQANAPMFPVILECLGSDALTWAIHEIVGMLDQPLSHRQITVRNRK
LKSDKQKSLQKQLHKTELTDEDDALKQAIALSLNDYGQTSDLQHAGLSRCSKNQSDTMSR
NEKRKTKIFKSRVQMTEDDLVINFCQFDEVGKGNITLRDVQRMANSHDFIWTDKELADMV
RCFDSDRDGKLSLDDFRHIVLRCNMLLVPENP
>Sgl16757 E3_activity/RING/RING 25.3 8.2
MASTGEADRKRRQVSSISPTAAGGMAKKQPFAPVSEDKKLDIAVLKFQNQKMSEKVEVQN
LEIMALKKRVAQQIEKQQSFEKMYTAFNNCSNKLLDGMEARSVHIRNLVCGEGNSHHPGV
MEDGSSSSDADPFLKRLKESYAPEPCLASNTLDQMLDDGDKASQKARNIVRNILAAVDVL
CRNKDDLYAAVLTALPEDGSCNRKAYEDMVAEVKNLQSALSDLLLKHRSLTRELRKHQVI
DMKNKAELKYLREMLECTIADLEESNQKLSAIKAEKDATEGAFFPVLNMGIKHGSNDRTT
DKQKDLQDMEVTLKESMDQSSSRLQELKQLHEERIEILKKLSDLQGTLKNVKSISCAPAF
KLLKEELEKSKADVIKYQALFEKLQVEKDKVTWKEKEVVIERQNVERKRIERKLEEASRE
PGRKEVISKFRELVSSFPEDMSSMQSQLHKYKEAAADVHSLRAEVQSLSNVLARKAKDLE
TLSSKSAEQDCEMGRLQAVVQDLKESDMELNLIVEMYRRESSVTRNLQAARDREYRAWAR
VHHLKSSLDEHNMEIRVKSAIEEEALSQRRLAAAEAEIADLREKCESSERNKSTLSNALN
SKKEENEAYLSEIETIGQAYDDMQNQNQHLLQQITERDDYNIKLVLEGQRSKQTHDLLLM
EKQSLQKKIQHASVLRDFFEMKASKIEDQVKGCSDQVHRLAEDRCQNSVSLENIQRRLLE
GRKASHQGKESLDELQNKVKDSRANLSGLQIELEKERFEKKRVEEELEAMKRKAERLREQ
NESSVAGKLRQELQQYKEILKCSVCRDRPKEVVITKCYHLVCDPCVQKVIESRNRKCPIC
AASFGPNDIMATSAEVVKKFVIASVFMWVLPIAIIHGFQNNLFPGVANISPYYQTLLVGF
LAVISVNVVIVFYICMALKEPSDKHEPDPKFVAEAKASINQSKSASGDKEE
>Sgl16777 E3_adaptor/Cullin_RING/SCF/F-box 12.5 0.0
MSRRVRRKVAKKGKEKLLLPSYPELIIDENDEEEDDDDLLHSNFPINPTSNSQKPQKNNS
INPRNDFVDWTRLPDDTVIQLFSLLNYRDRASLSSSCKTWRNLGFTPCLWESLDLRAHRC
DFNTAFSLSSRCSNLRRVRFLGADSADAIIHLKARNLTDISGDFCRKITDATLSVIAARH
EMLESLQLGPDFCERITSDAIRAVAMCCPRLRKLRLSGVREIHSDAINALAKHCVHLSDI
GFMDCLKVDETAMGNLSSLRFLSVAGTSNLKWGLVSHLWSKLPNLIGLDVSRTDVSPTAV
SRMLLSCQTLRVLCALNCVHVEEDANFLTSRSVGSKGKLLLSLFTDIFKGVGSLFADNSM
KGRNVFLDWRDTKRNEKNVDDIMSWLEWMLSYSLLRIAEGNPQGLDNFWVSQGATLLLSL
MQSSQEDVQERAATGLATFVVIDDENTSIDGQRAEAVMRGGGVQLLLNLASSWREGLQAE
SAKAIANLSVNTNVAKAVADEGGITILANLARSMNRLVAEEAAGGLWNLSVGEEHKGAIA
EAGGVKALVDLIFKWSTGGDGVLERAAGALANLAADEKCSMEVALSGGVHALVMLARNCK
FEGVQEQAARALANLAAHGDSNSNNSAVGQEAGALEALVQLTHSAHEGVRQEAAGALWNL
SFNDLNREAIALAGGVEALVALAQSCSNASPGLQERAAGALWGLSVSEANSIAIGREGGV
APLIALARSEAEDVHETAAGALWNLAFNPGNALRIVEEGGVPALVHLCSSSVSKMARFMA
ALALAYMFDGRIDEVALAGTSSDGMSKCVSLDGARRMALKHIEAFVLTFSDPHAFAAAAA
SSAPAALAQVTEAARIQEAGHLRCSGAEIGRFVAMLRNPSSILKACAAFALLQFTIPGGR
HAIHHANLLQNAGAPRVLRAAAAAATAPLEAKIFARIVLRNLEHHLVEISI
>Sgl16799 E3_activity/RING/RING 26.2 8.4
MAEEDEILMEVEAVEAVYGDDCIILNRFPPHLHLHIKPRTADVDSQQFVEATIELRAGPQ
YPSDPPYIAIIGSKGLNEERQTHLSNSLHDKAHELTSCLMLVALCEDAVEILNSMNHPEG
DCPLCLYPLVLEDIHSEAQPFMKLMSCFHCFHCECIVRWLTWIQKQNEASCGTSSTLLSD
VNEENDLVSDLHKLMGGSTGNCPVCRKVFLAKDIEHVLNSVGSYDADSDVYEKELVEKVL
QCDLETGRREEFEAILKLQQQCGGLIEPPKDNVLYSRICIQDLVREGNEVMNGEASEQQH
TNQIVVEEPASSSSSNQVSRRAVETRKQHRRGHRAVVEPASNAPPTGSGTGHRRHSGTRK
HGRDNSRWQVKPCSKE
>Sgl16837 E3_activity/RING/RING 34.4 9.6
MVRRRLLDDAHQSGNDVSPNILITVLVLAIAVILSASLYLLLRFFRRNNNNNTHNHSHSH
SHSRHRPHSLSSTNRHVISRRVTPENKAHNSLMEALPLFTSESLKTTGDCAVCLSKFEQK
DLLRLLPICCHVFHADCIDTWLNSNQSCPLCRSPVFLPDSELLSKLVPQQQDTSSVSSGS
FRVEIGNVSRRNENSGEFPVRRSYSLGGNFDYIVDDDVVSEVHSGSFRRTSSTTEFKTDT
ENNNNNLQQQSALAAEVGTRGGGGGGGWLKDYLTHSLSSSFRSSGRWFFTGSSRRETTTT
NEFGESEMDLEASRLGDEIGELFRWLSGV
>Sgl16842 E3_activity/RING/RING 25.6 13.6
MEIFHELMGKLVIFISTIVAIFPVLRRFMRHKGRLPATTYRGKPNEEGVFCMVCYDWVSR
GERVRVMPKCKHCYHVDCIDAWLGSHCTCPICRDQVIHALHQQQRIKRRNVIVSLLIIVE
DLSTKFGYPLDFGMSLLMSSCV
>Sgl16852 E3_activity/RING/RING 34.3 9.6
MVRRRLLDDAHQSGNDVSPNILITVLVLAIAVILSASLYLLLRFFRRHNNNHSHSHSRHR
PHSLSSTNRHVISSRVTPENKAHNSLMEALPLFTSESLKTTGDCAVCLSKFEQKDLLRLL
PICCHVFHADCIDTWLNSNQSCPLCRSPVFLPDSELLSKLVPQQQDTSSVSSESFRVEIG
NVSRRNENSGEFPVRRSYSLGGNFDYIVDDDVVSEVHSGSFRRTSSTTEFKTDTENNNNN
NLQQQSALAAEVGTRGGGGGGGWLKDYLTHSLSSSFRSSGRWFFTGSSRRETTTTTSTNE
FGESEMDLEASRLGDEIGELFRWLSGV
>Sgl16859 E3_activity/RING/RING 24.7 14.2
MEILHELMGKFVIFISTMVAIFPVLRRFLRHKGCLPATTYRGRSNEEGVFCMVCYDWVSR
GERVRVMPKCKHCYHVECIDAWLDSHCTCPICRDQVIHALHQQQRVKRRNVIVSLLIIVE
DLSTKFGYPLDFGMSLLMSSCV
>Sgl16870 E3_adaptor/Cullin_RING/DCX/DWD 136.1 24.1
MEEEEIEKAVIAYLKKKGFKQTELAFQEEQLQQQPQQSKNSSSNSQTDPDVAKLILTFSS
ESESLPAQYHDGYSKLRSWAYNSLDLYKHELLRVLYPVYIHCFMDLVAKGHLQEARTFFN
TFREDHETMHQRDLLKLEGVLSPSHLEEMEFAHTLRQSKVNIKICQYSYDLLIQYLHKDQ
SMTMLGVINEHINFEVFPGQGGSIFDDAEAVMLVDGGQDAANLINQKEIQWGMLEDSIED
RLEKNGGLLLDSEKVDGDNKEGENEENKKRSADGGKPGALVKKTKKDKVGGAGGKSARPE
ANTPTMAPRVKPELSLPVVPTEVEHSILEDLRNRVQLSSVALPSVSFYTFINTHNGLNCA
SISHDGSLVAGGFSDSSLKVWDMSKLGQQMGSSAHQGESAAGNEQMLGANGGKRPYTLFQ
GHSGPVYSASFSPLGDFILSSSADSTVRLWSTKLNANLVCYKGHNYPVWDVQFSPYGHYF
ASCSHDRTARIWSMDRIQPLRIMAGHLSDVDCVQWHVNCNYIATGSSDKTVRLWDIQSGE
CVRIFIGHRSMILSLAMSPDGRYMASGDEDGAIMMWDLASGRCITPLVGHTSCVWTLAFS
GEGSLLASGSADCTVKLWDVNASTKMLRSEEKSGSSNRLRSLKTLPTKATPVYSLMFSRR
NLLFGAGALSKPS
>Sgl16873 E3_activity/RING/RING 36.9 5.8
MASTTPISIGAPQPWLSPSPSSSPPPSSSKAYNYGYDCSVALCSINCPQFCSVFPPPPPL
FLNNSSDGDDSSSSRISPLMAALIAVLAAAFLLLFYFTVISRFCRNRRRRHNNNRLLNSN
RVDSLIHDPTRPETATTSGLDDSFIRQITVFKFRRSDKLIEATECAVCLSEFNEEENLRL
MPNCEHAFHLPCIDEWLKSNSNCPLCRSSMNPAPPPPPVRSTASVAALRVQRSNDAVLVI
REYPLQLVVDPTPQPPSTQNDDRHHQVGSRECRNNHVDESETKLEINNNNSR
>Sgl16880 E3_adaptor/Cullin_RING/DCX/DWD 33.4 2.6
MEDGNTRQYGVPLYGASWVPYNAIRSINPNSDDVDADNSAVTSPEILVVAGGGGEGNSGI
PNAILLSQYDSSTNSLSPQPIFRLGTDSELPYRIAVHPRGDGIICAFPNGCRWFDWEMTN
SNGDRDLSLRSTDKVHTRLEGVCQQLALTFSEDGSLLAVGGEDGKIRVFKWPSMDVLVDE
NEAYIEVKDLHFSIDGKHLVSVGNGGPCKIWDVASSKVVASLRKENDENFRFCRFSQSSE
RDQVLYTLATGGKGVSIISWNTKSWKRIAAKHITRDPVSAFNVSIDGKLLAIGTVEGGIL
IINSSKMQVQMTVKTAHMGLVTALTFSHDSRALGSTSMDSSVTVTLVQDNSANGTKNWII
MFVILLAIAVYFLKSQGFLPAGLPFSLSD
>Sgl16896 DUB/USP 211.4 0.0
MIVFGSFTEDEIRSLQGNQPEKSEVPVSKNELQFGSLPCVPDDLLSAANGESGKKLASFV
KSPLQSAKKDVGTVTSKDVVPGSGKVLKENGSISGSELSCPLANGNKQINDGGPQLASPC
TTESVRTVVSQQLSSQPQDGQDIRSKERYSNGVHDGSVASLKIVPLNDLKKVSNGSVVTT
GDLLPRGLINAGNLCFLNATLQALLSCSPFLKLLQELRARDIPKVDYPTLIAFVDFVSEF
DIPLGLSSKMKDSNVVETGMPFSPAMFEGVVKKFTPDVPSGFSGRTRQEDAQEFLSFVMD
QMHDELLKLGGQGSGMALGKLSLVSSSEDDEWETVGPKNKSAVTRTQSFVPSELSAIFGG
QLRSVVKAKGNKASATVQPYLLLHLDIFADAVHTIEDALRLYCASETLEGYRASNTGKAG
VVRASKYVKIQTLPKIMIIHLMRFSYGSQGSTKLHKPVYFPLELVLNSSLLVTPINEGRK
YELVATITHHGRDPSKGHYTADARYSDEQWLRFDDASVTPVPTSKVLHDQAYVLFYKQV
>Sgl16951 E3_activity/RING/RING 21.5 1.8
MGSACCVPARDATLSNRRRIGESQRPVRYSPTWSFRWDNYRRVAGEIENPCQSSERTSVD
VRMALKDSVGSDREIVSDGGSPLDNLGTPISQKSPSYEGVSTNYMSPSETSTTSNHFSKV
KNNIEVPEIGAVPPTLQYSMPSCSSFSTPGEPLCSQRQLLPASSTPSRRARRSPGHQLFR
QISDSRILGLKSPNSNSVSEGRQSFVLSTYSNDLVGGSSDGWSLRTFSELVASSQRERWS
FDSERFGSGRHKISESSSRFSYSPSLDLQTCGACLKVMAELSVIAVLACGHVYHAECLET
MTTEGEKYDPVCPICTVGQKQASKMSRKASKAEADLRMKFQKISRNRVIDSYLDGEVDNP
GRQKIIAKGKFPKMESSSSSRISFAKPFLKRHFTLGSKLGKSNSEHQSGKKKGFWARYRR
D
>Sgl16963 UBD/UBC-like/UBD_UBC 84.7 0.0
MTSSSTQSPKALSKIAQLRLQKELVEWHDPPVGFKHKVTDNLQRWVIEVSGAPGTLYANE
TYNLQVDFPEHYPMEAPQVIFVPPAPLHPHIYSNGHICLDILYDSWSPAMTISSICISIL
SMLSSSTSKERPADNDRYVNNCRNGRSPKETRWWFHDDKV
>Sgl17078 E3_activity/RING/RING 21.7 1.8
MGSACCVPARDATLSNRRRIGESQRPVRYSPTWSFRWDNYRRVAGEIENPCQSSERTSVD
VRMALKDSVGSDREIVSDGGSPLDNLGTPISQKSPSYEGVSTNYMSPSETSTTSNHFSKV
KNSIEVPEIGAVPATLQYSMPSCSSFSTPGEPLCLQRQLLPASSTPSRRARRSPGHQLFR
QISDSRILGLKSPNSNSVSEGRQSFVLSTYSNDLVGGSSDGWSLRTFSELVASSQRERWS
FDSERFGSGRHKISESSSRFSYSPSLDLQTCGACLKVMAELSVIAVLACGHVYHAECLET
MTTEGEKYDPVCPICTVGQKQASKMSRKASKAEADLRMKFQKISRNRVIDSYLDGEVDNP
GRQKIIAKGKFPKMESSSSSRISFAKPFLKRHFTLGSKLGKSNSEHQSGKKKGFWARYRR
D
>Sgl17091 UBD/UBC-like/UBD_UBC 84.7 0.0
MTSSSTQSPKALSKIAQLRLQKELVEWHDPPVGFKHKVTDNLQRWVIEVSGAPGTLYANE
TYNLQVDFPEHYPMEAPQVIFVPPAPLHPHIYSNGHICLDILYDSWSPAMTISSICISIL
SMLSSSTSKERPADNDRYVNNCRNGRSPKETRWWFHDDKV
>Sgl17119 E3_adaptor/Cullin_RING/DCX/DWD 126 14.0
MLTKFETKSNRVKGLSFHPKRPWILASLHSGVIQLWDYRMGTLIDRFDEHDGPVRGVDFH
KTQPLFVSGGDDYKIKVWNYKLHRCLFTLLGHLDYIRTVQFHHESPWIVSASDDQTIRVW
NWQSRTCISVLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIGALRKKSVSPADDLLR
LSQMNTDLFGGVDAVVKYVLEGHDRGVNWASFHPTLPLIVSGADDRQVKIWRMNDTKAWE
VDTLRGHMNNVSCVLFHSRQDIIVSNSEDKSIRVWDATKRTGLQTFRREHDRFWILTAHP
EMNLLAAGHDSGMIVFKLERERPAFAVSGDFVYYVRDRFLRVYEFSTQKDTQVIPIRRPG
STILNQSPRTLSYSPTENAIMIASDVDGGSYELYIIPKDGLGRGDMVQEAKRGLGASAIF
VARNKFAVLERSTNQVLVKNLKNEIVKKVALPAIIDAIFYAGAGNLLCRAEDKVLVFDPQ
QRIVLAELQTSFVRYVVWSNDMESVALLSKHSIIIATKKLEHRCTLHETIRVKSGAWDDN
GVFIYTTLNHIKYCLPNGDNGIIRTLDVPLYITRVSGNTIFCLDRDGKNRVISIDATEYF
FKLSLLRKRFDQVMGMIKRSELCGQAMIAYLQQKGFPEVALHFVKDEKTRFNLALESGNI
EVAVASANVIDDKTHWYKLGVEALRQGNADIVEYAYQKTKNFERLSFLYLITGNMEKSYK
MLKIAEVKNNVMGQFHNALYLGDIQERVKILEAAGQLPLAYITAKSHGLDDVTERLAAEL
GDEIPEIPQGKSQSLLMPPSPISCGANWPLLTVMKGMFDGLGYEKDAQEDEDEEVVDTWS
EALEIIDDDMVNGVVSADDGEEVDDEDEDAGWDLNLELPPEVETPKMSNGRSSVFNAPSP
GMPVSEIWKQRSSLAAEFVAAGSFDTAMRLLTRQLGIKNFAPLKPLFIDIFSASHSYMLA
FPSAPVISVALERGWSEASSPNVRGPPSLVFSFSQLEEKLRAGYKLTTAGKLSEALKTFT
NILNTIPLIVVETRREVDEVKELVIIVKEYVLGLKMELKRRELQDNPVRQQELAAYFTHC
NLQVPHVRLALLTAMKNCYKAGNLSTAANFARRLLETNPSVENQAKTARQVLQAAERNMK
DSTEINYDFRNPFVVCGATYVPIYRGQKEVSCPYCSSHFVPDQEGQICAVCDLAVIGADA
SGLLCSAAQKR
>Sgl17150 E3_adaptor/Cullin_RING/DCX/DWD 73.8 9.8
MSQKRPPPDPIAVLRGHRASVMDVCFHWCKPLLFSGSSDGELRIWDTVQHRTLSSAWVHS
AAHGIMCVASDPCIGDDKILSQGRDGTIKLWEIGNGGICRTPSVTFGTNSYHFCKLSMVK
KPINQKQKHVAGSGDVAADLVRDSTVNTLENQSEHSNDVQIEGAQYVVVAGEQPSQVEIW
DLNTAERCARLPEVSSDGLANGSEKARGMCMAVQAFIPPQCQGSLHILAGYEDGTMAWWD
VRNTMKPLTSVKYHSEPVTSLSVDQSCNGGISGAADDKIVLFNMDYDRGTCVVRKEISLG
RPGIAGTSIRSDGKIAATAGWDRRVRIYNYRKGNDLAILKYHSAMCNAVSFSRNCKLLAS
SSEDTTIALWELYPPRNTTGAV
>Sgl17182 E3_adaptor/Cullin_RING/BCR/BTB 29.7 0.0
MLEIEMEESRSGTINISDVSYDALRAFVNYLYTADASLDEQMACDLLILAEKYEVKHLKT
YCENFLVSKLNWDNSLTTYSFAHRHNAKRLLESALSMVIDKMENLTKSEEYAHLVQKDPR
LIVEIYEAYMSKQLNTVARIG
>Sgl17184 E3_activity/RING/PHD 57.7 43.9
MVIEENGNGNGNDTGTVNGSSNSSSGKTVNVFLHGSSSGSDGFAADGSSLRTYKRRKCGL
SSSNTKIIDLEKPPCSTSAPLDDNNKMVKELVDIGLQKNSCEQVSDSKINCPSLLNGSDD
GSYQHWRNALESIFQSVCPTENGGGGVLDCITEALLRNPTNTDKETLYHCHSQSHMQSTG
MSNGFFSASEGISSVISNGASSESGHSSVSRQCQLVFYRLLMSGKFALLCKMLSENFHGL
KIEKLLEFGPINSRIKEGAYESKPMLFSSDIQQVWTKLRLIGSEMVSLSNNMSQLSRAFC
HDLAGGAAFDTSSEKRRKLSCRKYDVRVKQEEQDPSVFCTCRKCGERSDGRDCLVCDFCE
GMFHVSCIKPAVKEIPLKSWYCANCFASGNGSPHEDCAVCEQLIATCGVNGVDAVPVSEA
VLIDDHDEESSDGVIETGVQIFKGSKQLFCKLCGSTLNEGEEYRMCEHPFCMYKYYHTRC
LTNKEMTTYGPHWYCPSCLCRGCLTDKDDNNLVMCDGCDHGYHIYCMNPPRTSIPKGKWF
CSKCNVGIKAIRKVKKLYDNLEKKQIKDEGKCVGSPSNKSKEGFENAGGGSGGVDMLLSA
ARKLNDETDGNR
>Sgl17186 E3_adaptor/Cullin_RING/SCF/F-box 19.4 0.0
MARQQGLRTEDLDSFKKLMVFGAALDEMGGETTAEWKDIPMELLLRIMNLLDDQTVIKAS
EVCSGWREAIGLGLTHLSLSWCKNNMNNLVPSLVPKFANLQSLILRQDKPQLEDNAVETI
ASFCHDLQELDLSKSFKLTDRSLYALAHGCPNLRKLNISGCSAFSDAALAYLTSYCKKLK
SLNLCGCSGAATDKALQSIAYNCKELQTLNLGWCENVGDLGVTSLAYGCPNLRALDLCGC
VLITDESVIALANGCPHLRSLGLYYCQNITDRAMYSLAQSRVRNKHGVWPSIKNRYEDDG
LMSLNISQCTALTPPAVQAVCDSFPSLHTCPGRHSLIISGCLNLTSVHCACAIYGHRAAS
TIAH
>Sgl17196 E3_adaptor/Cullin_RING/BCR/BTB 63.5 0.0
MSRNHQQQQQQQQQHVSLYCLSCKEEYCTNDVGTCKECYEEASETEEELKKEIEYLKSKV
AFLRLGSSPIDSNKRSSSLGFTDVVLVATDEFQDNPLSLPAHKAVLASRSPVFKAMLEIE
MEESRSGTINISDVSYDALRAFVNYLYTADASLDEQMACDLLILAEKYEVKHLKTYCENF
LVSKLNWDNSLTTYSFAHRHNAKRLLESALSMVIDKMENLTKSEEYAHLVQKDPRLIVEI
YEAYMSKHLNTVARIG
>Sgl17197 E3_activity/RING/PHD 58.8 44.4
MVIEENGNGNGNDTGTVNGSSNSSSGKTVNGFLHGSSSGSDGFAADGSSLRTYKRRKCGL
SSSNTKIIDLEKPPCSTSAPLDDNNKMVKELVDIGLQKNSCEQVSDSKINCPSLLNGSDD
GSYQHWRNALESIFQSVCPTENGGGGVLDCITEALLRNPTNTDKETLYHCHSQSHMQSTG
MSNGFFSASEGISSVISNGASSESGHSSVSRQCQLAFYRLLMSGKFALLCKMLSENFHGL
KIEKLLEFGPINSRIKEGAYESKPMLFSSDIQQVWTKLRLIGSEMVSLSNNMSQLSRAFC
HDLAGGAAFDTSSEKRRKLSCRKYDVRVKQEEQDPSVFCTCRKCGERSDGRDCLVCDSCE
GMFHVSCIKPAVKEIPLKSWYCANCFASGNGSPHEDCAVCEQLIATCGVNGVDAVPVSEA
VLIDDHDEESSDGVIETGVQIFKGSKQLFCKLCGSTLNEGEEYRMCEHPFCMYKYYHTRC
LTNKEMTTYGPHWYCPSCLCRGCLTDKDDNNLVMCDGCDHGYHIYCMNPPRTSIPKGKWF
CSKCNVGLKAIRKVKKLYDNLEKKQIKDEGKCVGSPSNKSKEGFENAGGGSGGVDMLLSA
ARKLNDETDGNR
>Sgl17199 E3_adaptor/Cullin_RING/SCF/F-box 19.4 0.0
MARQQGLRTEDLDSFKKLMVFGAALDEMGGETTAEWKDIPMELLLRIMNLLDDQTVIKAS
EVCSGWREAIGLGLTHLSLSWCKNNMNNLVPSLVPKFANLQSLILRQDKPQLEDNAVETI
ASFCHDLQELDLSKSFKLTDRSLYALAHGCPNLRKLNISGCSAFSDAALAYLTSYCKKLK
SLNLCGCSGAATDKALQSIAYNCKELQTLNLGWCENVGDLGVTRLAYGCPNLRALDLCGC
VLITDESVIALANGCPHLRSLGLYYCQNITDRAMYSLAQSRVRNKHGVWPSIKNRYEDDG
LMSLNISQCTALTPPAVQAVCDSFPSLHTCPGRHSLIISGCLNLTSVHCACAIYGHRAAS
TIAH
>Sgl17212 E3_activity/RING/RING 34.5 7.3
MSNAAYGGRRASRRIAETNQIEGGASILTSKNGGGSNTEAMKLYEAIIFSGPIVFTLIIL
FLFYFFYLRRSVDWSSLRMRPTNSAAATADSDDLEVAELGLKKEFREMLPIIVYKESFSV
RDTRCSVCLGDYQAEDKLQQIPGCGHTFHRSCIDHWLATHTTCPLCRLSLVSPSKTPPTS
ERDSQESQDQADNNNDSTENVDDVLQQNRVQVLSVHTVV
>Sgl17235 E3_adaptor/Cullin_RING/DCX/DWD 26.1 8.1
MAQFLFQNDELEFIDDIYQMTNFEDELLGFSDSSTPRTNRSNNDDDDDDSFDSDVDDDFD
FCEGQGKLKSDTTSMEARNGIDIQGIPWERLNFTRDRYRETRLKQYKNFESLPSSSRQQE
LAKECKQVKKGYTFYDFQFNTRLIKSTIVHFQLRNLLWATSKHDVYLMQNSSVMHWSALC
KRSKEVLNVARPIVPTTKCLQSLPQPLSRVQISTMCVKDNMLVAGGFQGELICKYINQQE
VAFSTKVTTEENAITNAVDICNSSSGSKWVIVGNNDAHVRVFDSANFVCFNQFRFPWSVN
STSVSPDGKLMAVLGDSTECLVSDSHTGKVIGTLKGHSDYSFASAWHPDGQILATGNQDT
TCRLWDIRNMSQSLEVLKGRMGSIRALKFSSDGRFMAMAEPADFVHIFDTKSGYEKAQEI
DLFGEIAGISFSPDTEALFVGVADRMYGSVLEFNQRHCNGYLEAIF
>Sgl17298 E3_adaptor/Cullin_RING/SCF/F-box 15.9 0.0
MVKCYPFEKDIIFGGGRKVKMNEEEGNEIRQWDELIPDALGLIFKKLSLEDILTVIPRVC
KSWGKAAQGPYCWQEIDIDEWSTDCQRDKLDRMLRLLITRSSGSLRKLHVSCVNNDQIFS
FIAENAGSLQSLMLRRSEISDSIVEQLAGKFSKITSLDLSYCCRISTSGLEAIGKNCKLL
SSLSWNMHPLASAYNKPSHVDEARAIAQTMPKLKQLEIAYLQINKESVYDILLGCPNLEF
LDLRGCWNVHLDKKALEKRHPKLAVLGPQVVMGAFEKQAFFDDYYSDSDFSDYGYMDYSD
DESFDGMWDDEELEFRVYEGADYMYEFGWPPSP
>Sgl17313 E3_adaptor/Cullin_RING/DCX/DWD 29.4 7.2
MLRNLLWATSKHDVYLMQNSSVMHWSALCKRSKEVLNVARPIVPTTKCLQSLPQPLSRVQ
ISTMCVKDNMLVAGGFQGELICKYINQQEVAFSTKVTTEENAITNAVDICNSSSGSKWVI
VGNNDAHVRVFDSANFVCFNQFRFPWSVNSTSVSPDGKLMAVLGDSTECLVSDSHTGKVI
GTLKGHSDYSFASAWHPDGQILATGNQDTTCRLWDIRNMSQSLEVLKGRMGSIRALKFSS
DGQFMAMAEPADFVHIFDTKSGYEKAQEIDLFGEIAGISFSPDTEALFVGVADRMYGSVL
EFNQRHCNGYLEAIF
>Sgl17326 E3_adaptor/Cullin_RING/SCF/F-box 14.3 0.0
MRKKNKNSWNNYFPLELEKEILARLPVKSLLQFRCVSKSWCSIIDSPDFKLHNNNNNSEN
PKFISIIEYRHNLSIALRRSDTFRKIGAEIANFDHWYVICQFCKGLVYISRLFTRKLWNP
SIKKCLTIPNCPVLGEEKLWVCFELGFAPSSNDYKVLAIDWVGYIGVYSVNDHRWRVKNI
QLPRLSALQRSEIKRVVFSGGAKYRVMFDDQSGGPVICVFDFDIEELSLVQPPDAVKGSM
VWFIFRFGESIGVFTMSHERSCIWIMERNGGLSKTGCNWRLWFTGEPNLDACSLFKSIEK
EIFFVQKTCTFLMVKRTGSNPNLRRDRLMSYNLIKNEIKHLAKSLRSYILFDTYVESLVL
HKGIEGQTISSLP
>Sgl17330 E3_adaptor/Cullin_RING/DCX/DWD 31.4 8.8
MQGGSTGIGYGLKYQARCIADVKADTDHTSFIAGTLSLKEENEVHLIRLSNGGTELVCEG
LFSHPNEIWDLASCPFDQRIFSTVYFNGESYGAAIWQIPELYGQLNSPQLERIAALDSHS
GKIRSTVAAFYGSAMVCNFAMSETERGIGLTFAQIFVACTGLTSEIVLWWPTGRHDKLIS
IDEQNLLLWSLDSSKKTAQVHSQESAGMLHYLTGGAWDPHDVNAVALYSESAIQLWDLRT
MKMSSAIEQVHARSVDYDAKKSHILVTAEDESGIRIWDLRMLKAPIAELPGHAHWTWTVK
SNPEFDGLILSAGTDSSVSLWLASTSSSADATPESLVVSPTMCADPLLNTYSDYEESVYG
LAWSSREPWIFASLSYDGRVVVESIKPHLSKK
>Sgl17365 ULD/UDP/UBQ/UBQ_PIM 51 0.2
MAEQQSAEGASTSDGSAAVADSMVEINIKTLDSRMEIADQIGVPVGQQRLIFRGKVLKDE
HLLSEYHVENGDTLHLVERQTTQPQTSTDSSGAIGGQGTDGGVGAPRNRIGQISHSVVLG
TLNVGDQGEGGTTDLNRVIGAVLNSLGVGNQTASAAFGAPSTAPANPSGLGPQGNDAERG
RGGNGSLNQAGNQAPFGQPFLSQAFQVPLAGVSIPSPPLSMPISDSLNTLSDFMSRMEGV
LSQNGYQPSSSPSGTADQPATELPLNARGLPTPEALSIVLRHAQRLLSGPAVAALSHIAG
RMEQEAGSTDASVRSQIQSESVQVGLAMQHLGALFLELGRTILMLRMGQSPAEAVVNAGH
AVYISSSGPNPIMVQVSSRIFQSVGFAVSHQTSPLFNTPAVSAANTGTSVPVGIIGSAPP
RHINIHIHAGTSLASMGSAVGARAAGGESAQGQSTGVASSAIAVSPVPNMSQPIGVVSTS
QPPDAASLSSVISQVNSRIRSFLENMNTDNQTPSVSGQQENPVVPSSSAGSGGGVR
>Sgl17381 E3_adaptor/Cullin_RING/SCF/F-box 17.7 0.0
MNPNPELPEDIILAEILPRLPAKSLVRFKSVCRQWKTFISSVEFSKTHLHHPSFLSSTRR
SILTHGYSGDSTVFEAVDFYDADRNADSNNLYLTNLGKQFTALFKHLDLSASCNGLAFLI
ASPAIKKHRLLNDYDRSYEFGYVIYNPVLGVGDYVEIPHPRWFPLGSADKGFIDDYVISR
HYNFGFGYDSKSDDYYIVAVDLPGDFKIVFYVYSLRSHRWEPKITRLGVKNNVSPLSFES
IWKFHGGTLVKETLHWGMSLGHDYNFILAYSLATRNEAKKMYLPQPKFGNARECGGGCGI
DFSLCCLGGCLCAWANYNDSNEGIIADMWMMKEYGVRKSWTKLFRIKLDDTAGCEKIFGF
TKSGKVLVFTSSHETFLVDFTCDLLPNISGHVFENENWWPDWAVDYNPSLVSVLAIISGL
>Sgl17384 E3_adaptor/Cullin_RING/SCF/F-box 17 0.0
MNPDPELPEDIILNEILPRLPAKSLVRFKSVCRQWKTFISSVEFAKIHLHHPSFLSSTRR
SILTLGNSGGNRHLEAVDLEAVEYYDADPNADSNNLYLTNFGEKFRALFSFLELSASCNG
LAFLIIASPALKKRPLPNDYDQSYEFSYVIYNPVLGVGDYVEIPHPLRLSLGSVERAQRG
LLGMFFSRHLNFGFGYDSKSDDYYIVAVDLRHFPGDVKIVLYVYSLRSQHWETYVETLVV
KDNGSLLLFESIWKMEVGTLVKETLHWAMSQGYDNHFILAYDLATRNEVKKMNYPRPRLF
CNTRECGGGIDFKLCCLGDCLGAWANYRGLGYVADYLCVADLWMMKEYGVWESWTNLFRI
HLYDSVGCLNFFGFTKSGMVLVFTSRDQFFLVDFTSGLPNISGPVLENKRHGAVDYNPSL
VSVLAIVSGLG
>Sgl17429 E3_activity/RING/RING 37 4.7
MLLSIFLALFLPCAGMSVVFVVYICLLWYAASNAPPEPPVKPTVKKGLSAAELEKLPKVT
GNQLIHGNECAVCLDDIEDDQPARMVPGCNHGFHLYCADTWLSKQPVCPVCRTKLGPEFF
ESSTTQNPC
>Sgl17464 E3_adaptor/Cullin_RING/SCF/F-box 14.1 0.0
MRKKNKNSWNNYFPLELEKEILARLPVKSLLQFRCVSKSWCSIIDSPDFKLHDNNNNSEN
PKFISIIEYRHNLSIALRRSDTFRKIGAEIANFDHWYVICQFCKGLVYISRLFTRKLWNP
SIKKCLTIPNCPVLGEEKLWVCYELGFAPSSNDYKVLAIDWVGYIGVYSVNDHRWRVKNI
QLPRLSALQRSEIKRVVFSGGAKYRVMFDDQSGGPVICVFDFDIEELSLVQPPDAVKGSM
VWFIFRFGESIGVFTMSHERSCIWIMEENGGLSKTGCNWRLWFTGEPNLDACSLFKSIEK
EIFFVEKTCTFLMVKRTGSNPNLRRDRLMSYNLIKNEIKHLAKSLRSYTRIFFDTYVESL
VLHKGIEGQTISSLP
>Sgl17468 E3_adaptor/Cullin_RING/DCX/DWD 31.4 8.8
MQGGSTGIGYGLKYQARCIADVKADTDHTSFIAGTLSLKEENEVHLIRLSNGGTELVCEG
LFSHPNEIWDLASCPFDQRIFSTVYFNGESYGAAIWQIPELYGQLNSPQLERIAALDSHS
GKIRSTVAAFYGSAMVCNFAMSETERGIGLTFAQIFVACTGLTSEIVLWWPTGRHDKLIS
IDEQNLLLWSLDSSKKTAQVHSQESAGMLHYLTGGAWDPHDVNAVALYSESAIQLWDLRT
MKMSSAIEQVHARSVDYDAKKSHILVTAEDESGIRIWDLRMLKAPIAELPGHAHWTWTVK
SNPEFDGLILSAGTDSSVSLWLASTSSSADATPESLVESPTMCADPLLNTYSDYEESVYG
LAWSSREPWIFASLSYDGRVVVESIKPHLSKK
>Sgl17496 ULD/UDP/UBQ/UBQ_PIM 67.8 0.2
MIIVGPNDQYVDPYAREVMPDYGALFLPSIFTWCVSNFVTNMAEQQSAEGATTSDGSAAV
ADSMVEINIKTLDSRMYNFRVEKNIPVSLFKGKIADQIGVPVGQQRLIFRGKVLKDEHLL
SEYHVENGDTLHLVERQTTQPQTSTDSSGAIGGQGTDGGVGAPRNRIGQISHSVVLGTLN
VGDQGEGGTTDLNRVIGAVLNSLGVGNQTASAAFGAPSTAPANPSGLGPQGNDAERGRGG
NGSLNQAGNQAPFGQPFLSQAFQVPLAGVSIPSPPLSMPISDSLNTLSDFMSRMEGVLSQ
NGYQPSSSPSGTADQPATELPLNARGLPTPEALSIVLRHAQRLLSGPAVAALSHIAGRME
QEAGSTDASVRSQIQSESVQVGLAMQHLGALFLELGRTILMLRMGQSPAEAVVNAGHAVY
ISSSGPNPIMVQPFPHQTSPLFNTPAVSAANTGTSVPVGIIGSAPPRHINIHIHAGTSLA
SMGSAVGARAAGGESAQGQSTGVASSGETGVTPVFPGRNVIATAAPSRTAAIAVSPVPNM
SQPIGVVSTSQPPDAASLSSVISQVNSRIRSFLENMNTDNQTPSVSGQQENPVVPSSSAG
SGGGNFDATNVSKSMHAESSGEANESLKDSVPGQQTQEDATEMRDNTQSDLLKSTEESGS
LAVSTSRGGSGELADKATGAREIPLGLGGGLQPKRRNRQSQMQPGNGEGGSSSSPDQSQQ
ARISGQQILQSLASRSTAARSSTDSGSGQAEQGQGQSMEGTQASLDTDGQLDVTGTMSQL
LQSPALDGLLSGVAQQTGVGSPDVLRNMLQQFTQNPAMRNTVNQLAQQVDRDEFRNMFTG
TGTGEDGSIDFSSMFQQMMPVVSQFLGGGSAQNEQLQNMMPQLLPQIDRGSLEDNSFGQA
FQEVVQMIANHSPSQDIFQAMVQNAALSTGVAEGELTDGLCSNQDLVDGFVEMLRRDLLH
RLQENSASGGNS
>Sgl17510 E3_adaptor/Cullin_RING/SCF/F-box 14.1 0.0
MRKKNKNSWNNYFPLELEKEILARLPVKSLLQFRCVSKSWCSIIDSPDFKLHDNNNNSEN
PKFISIIEYRHDNYSIALRRSDTFRKIGAEIANFDHWYVICQFCKGLVYISRLFTRKLWN
PSIKKCLTIPNCPVLGEEKLWVCYELGFAPSSNDYKVLAIDWVGYIGVYSVNDHRWRVKN
IQLPRLSALQRSEIKRVVFSGGAKYRVMFDDQSGGPVICVFDFDIEELSLVQPPDAVKGS
MVWFIFRFGESIGVFTMSHERSCIWIMEENGGLSKTGCNWRLWFTGEPNLDACSLFKSIE
KEIFFVEKTCTFLMVKRTGSNPNLRRDRLMSYNLIKNEIKHLAKSLRSYTRIFFDTYVES
LVLHKGIEGQTISSLP
>Sgl17514 E3_adaptor/Cullin_RING/SCF/F-box 17.6 0.0
MNPNPELPEDIILAEILPRLPAKSLVRFKSVCRQWKTFISSVEFSKTHLHHPSFLSSTRR
SILTHGYSGDSRVFEAVDFYDADRNADSNNLYLTNLGKQFTALFKHLDLSASCNGLAFLI
ASPAIKKHRLLNDYDRSYEFSYVIYNPVLGVGDYVEIPHPRWFPLGSADKGFIDDYVISG
HYNFGFGYDSKSDDYYIVAVDLPGDFKIVFYVYSLRSHQWEPYITTLVVKDNGSPLFFES
GWKMHGGTLVKETLHWGMSLGHDYNFILAYSLATRNEAKKMYLPQPKFGNAREFGGGCGI
DFSLCCLGGCLCAWANYNDSNEGIIADMWMMKEYGVRKSWTKLFRIKLDDTAGCEKFFGF
TKSGKVLVFTSSHDTFLVDFTCDLLPNISGHVFENENWWPDWAVDYNPSLVSVLAIISGL
>Sgl17563 E3_activity/RING/RING 29.6 7.1
MSAESPSTPPSSPPPLPPVTAAAQHWCYHCDKRVSVESQSGQPDEVICSDCKFGFVESLP
PTNSSSSLLSPPPESVVFSDEPTLGDQFIQVLRLLAHVAREDEPPLHAPPPPPSSAPEDP
PPDESETDVFGFGITLDNWHRELEDHNNHININVDGGDDDDDDAQEEEDDDDDDEEEVRS
VEIEGHTDEDEDEEEREEDIRRRRRDVLRLRLRDFANRARSEGRNRILDWAEILMGLEDN
SVEFRFELPESNDRYVGNPGDYVDAAEYEALLQNLADAEGRRGAPPASKTAVEGLKVVEI
KTVEESYACAICKDMVNVGECVKEMPCGHGYHGDCIVPWLAARNSCPVCRFELPTDDADY
EEERKKKKFPGSSSGSSGGTSV
>Sgl17566 E3_adaptor/Cullin_RING/SCF/F-box 15.3 0.0
MNPNPELPEHIILNEILPRIPATSLVKFKSVCRQWKTFISSAEFVKTHFDHPSYLSSTRS
ILTLGFDDERRLTLFEAVDYYHADSNNNLDLTNFGAHFKALFQYLSGSCNGLAFLIASPK
RKKYEFPNDDDGDDDDYDDSYEFSYVVYNPVLGVGDYVEIPHPRRFPLGDGVRGYFGRIY
SRYYSFGFGYDSKSDDYYIVAIDLPGNFKIVVYVYSLRSHQWEDYIGTLVVKHNDYDLPL
IFECMWYCHIGTLVKETLHWGMSQGHDNKFILAYALATRNQAKKMHLPRPRFGNARQGGG
ATDFNLCCLDDCLCAWANYEGSVADMWMMKEYGVWESWTNLFCIQLDHPVHCRNFFGFTR
SGMVLLFTNLDEFYLVDFTYDPPNIFGPVLENEKRSAVNYSPSLISVLAIISGPG
>Sgl17629 E3_adaptor/Cullin_RING/BCR/BTB 60.1 1.2
MLEKKQQKFLTVAPFECAWQKEFKFKEAGRGCVVFEAFARNDVTVVFRENVGSQHYHYKT
DSSPHYTVVFGSHRNRRLKIEVDGKAVVDVEGVGLCSSAAFQSYWISVYDGLICIGNGRY
PFQNVVFQWLDSNPNCNVQYVGLSSWDKHVGYRNVNVLPLTQNHISLWKQLDSRVYNEDE
EDEGGYEEPMSNDKWGLVNFLESWELSDVLFIVGVEERSVPAHKVILAAAGNFKFAPGED
IIQLQEVGYPILHAFLQYIYAGQSKILESQLGPLREIGVQFEVMPLVKQCEEIIERFKTN
KKLFDSGKNVEIFYPNCQSLRPTVFPYGLPINVSRLQQFYSTGEYSDLEVYVEDFGFVAA
AHKVVISLWSVPFLKMFTNGMRESSSTKVYLKEISSEAMKAMLDYMYHGELMLEDIEENN
TLLLHVLLLADQFGITHLQQECCKILLECLYEGWRLSNGSRSYIKRDSVCQVLQVISSVP
SCKVIEESCKRKMSMQFDYCTSASLDFTLLDEAIFRSILQHPDVTVTSEERVLNAIFLWS
LQAKELHGWEAVDAFLIHSAPEVLFGQRLDSLNRLLPLVRFPLMPYDLLEKLEKSSIMKS
VPAFANLVKEAINYAKFGVTWTEVEPNPRFHHRRSSYKELQYICDGDSNGVLYYAGTSYG
EHRWVNPVLSKRITITASSPLSRFTDPKVLASRTYQGTSFTGPRVEDGRICSWWMVDIGE
DHQLMCNYYTLRQDGSRTFIRHWNLQGSLDGKHWTDLREHKNDQKICKPGQFASWPVTGP
QALLPFRFFREKKSEMKVSVGFPSTIALGSVPLSAKRGSANFESFYVQQLGLNRSCNYLL
GSNFLHSKSKVHISHNAKHCHTISATVSESSQMMENAEEDTENLGILGVDSSLEPYKDHF
RYRMKRYVDQAQLIEKHEGGLEEFAQGYLKFGFNREEGSIVYREWAPAAQEAQLIGDFNG
WDGLKHSMEKNQFGVWSIRIPDYDGKPAIPHNSRVKFRFKHGNGVWVDRIPAWIKYATVD
PTRFGAPYDGVHWEPPLEERYLFKHPRPPAPKAPRIYEAHVGMSSSEPRVNSYREFADDI
LPHIKANNYNTVQLMAVMEHSYYASFGYHVTNFFAVSSRSGTPEDLKYLIDKAHGLGLRV
LMDVVHSHASNNVTDGLNGFDVGQSSQDSYFHAGDRGYHKQWDSRLFNYANWEVLRFLLS
NVRWWLEEYKFDGFRFDGVTSMLYHHHGINMGFSGNYNEYFSEATDVDAVVYLMLANHLV
CNLLPDAMMIAEDVSGMPGLCRPVSEGGVGFDYRLAMAIPDRWIDYLKNKKDEEWSMYEI
MSSLTNRRYTEKCIAYAESHDQSIVGDKTIAFLLMDQEMYTGMSCLTEASPIVDRGIALH
KMIHSITMALGGEGYLNFMGNEFGHPEWIDFPREGNGWSYAMCRRQWNLRDTDHLRYKFL
NAFNRAMNLSDDKFSFLSSSKQIVSSTNEEDKVIVFERGDLVFVFNFHPVNTYEGYKIGC
DLPGKYRVALDSDALEYGGRGRVGHDVDHFTNPEGIPGVPETNFNNRPNSFKVLSPPRTC
VAYYRVEDYPEESVSTSTVVADLLDDKADDQAEDDSPTPKEPTPAKESASLSKEDILPKD
VVVESSPANDVKFNPFKSCDYELSMPLLSSMHFPLVRAYLFSV
>Sgl17631 E3_activity/RING/U-box 117 0.3
MLTSKFRKSSSNLSLNCPIPYGTGDTKNGSPEGIIMVEDDNFSLITPKEGKDIIHDLEVL
IESIELIGEYRITQKKECQNLVRRIKILHLLLEEIKEINANPPPNSAHATFCNLRKALLC
AKKLLKTCAEGSKIYLAVEREKFTSMFQLVNSKISQAMDDIPYDDLNISDEVKEQTELMG
QQLKRTKRRTDTQDLELAMDLMVVFSKEDERNADIAIIERLAKKLDLRTNEELKEETKAI
KRLENDKRVEEHLEIIMDVLHKFKQSAGIVEDNNLMLEDDADQIIMNNPEEQQQQIIRSP
SNKDIPQEFLCPITLEIMTDPVIVATGQTYERESIQKWLDSNHKTCPKTGQVLQHLSLAP
NYALKNLILQWCEKNKIQVPRKQAHNNENESSPSFHYGNNEVSSTTTTTTLTTNENDESS
HPSSSPENKSTIITLVEDLSSSHLDVQREAAHKIRLLSKESPENRVLIAESSGIPPLIQL
LSCTDSKIKEHAVTSLLNLSIDGTNKRLITEEGAIPSIIHVLHNGNVGSKENAAATLFSL
SMLDENKVTIGLSDGIPPLVNLLANGTIRGKRDAATALFNLILNSMNKGRAIEAGIVKPL
LSLLEDEELGMIDEALSILLLLVSHPQGRQEIGQLGFIQALVDFMAGDGTPKNKEGAAAI
LLELGLNGGSSFLLAALQFGVYECLVDMSQSGTNRAQRKACTILQLMRQYEQIP
>Sgl17636 E3_adaptor/Cullin_RING/SCF/F-box 15 0.0
MKKKKNQISWNNYLPSELESEILARLPVKTLLRFRCVSKSWCSLIDSPDFNSLHFNLYNN
NNNNSENSKFIAIHEFRYNYSITLRRSDTFRKIGAEIANFDHPFSIRQFYKGLLLIRHNL
MMKLWNPSIGKCLIIPDCPVSELDFHMYYTLGFAPYSNDYKVVAINSKLGYTAVYSVNDH
CWRVKSIHRRGLPLSRLGYMNWVVVSGGVLYWRLYDDQSKSPVICVYDLDIEEFRLVQPP
GAVKGSMVWFIFRFGESLALFTMSDERSCIWVMEKNGGSDEDCNWMVWFTGEPNPDACSL
FKLIETEILFVQKTNTFVLVQKIPATVRHRVMSYNIISHEIKHLAKSLNREISFSTYMES
LALHKAIEGQTLSSFP
>Sgl17654 E3_activity/RING/RING 37.1 5.2
MSSSLVYIPCNHDYQTVNMEARQKFLQVHFISDLRYVFEANPNCPSCKSDMLTATISRVQ
CPIYCLQLQRDFEHRVENKITELLLRDDDHSNTLHDDLFVYNALHYDIDHRCEFCSLVDT
IAEIFMENTMIDRVLVESLLDDGMTNITTLAPASNNAIDELERFNIIIPSQQEKATTTTT
ATCAICLDELIRNNNNKDDELGVRMPCKHEFHEDCILVWLRKSHSCPLCRFNLPAGTHYS
SRD
>Sgl17681 E3_activity/RING/RING 39.1 5.4
MRFRFLRSLNTSSSSSSSSQSPPSDDGVDTVDSDFVVILAALLCALICVLGLVAVARCAW
LRRFSGGAASTPANKGLKKKVLKSLPKFSYSADQHAGKLSDDCAICLSEFISGEEIRVLP
QCGHGFHLSCIDTWLGSHSSCPSCRQILAVRCHKCGGGLPENSNTSSSSTTTAAAATATT
TSDEHHSHNHIHSSNNSTNQNRIGNDNANALPFLP
>Sgl17697 E3_adaptor/Cullin_RING/SCF/F-box 20.9 0.1
MFADTNIVEDGLRRDFESLSVSKKLVRSVSQKLRKKRVHRSAGDEEETANGFSLRCMSLY
GRGGGCKVGADTSEESGDSSTRRRSSASEEGKGYKPRCGAEETGVDCFSYGRKDRFWKRS
SRKDLEFEESQRNNRMNLSLPDDVLEMCLMRLPLSSLMNARLVCKKWNHLTSTPQFMQMR
RESLYQTPWLFVLGSVKDGYCSGEVHVLDVALNRWLTIHAEVLRGRFMYSVASMRDEIFV
VGGCSSLTSFGRVDRSSFKTHKSMLVFSPSTKSWRKVSSMKYARSSPILGISEVSLDCPI
IHSQSNRQDRRFPRSRLGGVSDIYEDPHRLSVRRQLRSLSDDNAGFLAPIKKQCRPSRHR
SETSSLRDCKRFVLIAIGGLGSWDEPLDSGELYDSISNRWIEIQKLPLDFGIVCSGVVCS
GTFIVYSESDKLAGYDIERGYWTLIQTTPSPPRVHEYYPKLVSCNNRLFMLSVSWCEGDG
QIGRRNKAIRKMWELDLTYLAWTEVSIHPDAPMDWNAAFVADKNLIFGVEMFKIFGQVLD
FFTVCDISDKVMKWSHISRNRVAQELDASSCVTKTIVAVHL
>Sgl17698 E3_activity/RING/U-box 84.1 0.1
MAGSSGGSTDLDSQSDDSSQVEKLHVEPIFSPFVCPLTKKVMRDPVAIENGNTFEREAIE
KWFRECKESGRKPTCPLTDENLKSTALNPSIALRNTIEEWTARNEAAQLDMTRRSLSTGT
SERDILQALRYVEYISEGSRSNKGAVHNPEILDLILRMLRNNSRKVRCKALETLRVITEQ
DSDLKEIMGEGDTVRIIVKFLSSDKFSEKEKEEAISLLYELSKSPNLSEKICSINGAVLI
LIGMTSSNSANVLVVDKADKTLDNLSQSENNVRLMAESGRLQPLLRLILEGTLETKLSMA
SFLGDLGLNNEVKFHVAKTVGSSLVNLMRNDDIQSREASLKALNQISSYDASAKVLIEAG
ILPPLVNDLFGVGGKQLPMRLKEVSATILSHVVNSGYDIDSVIIGPGNQTLVSEDIIHNL
LRLISNTGPSIECKLLQVLVGLTSSKTVHNVVSAIKSSGATISLVQFIEERDLRLAAVKL
LHNLSRYIAQELADALLAAGQLGALIRIISENNGITEEQAEAVGLLAELPKSDLALTHEM
LKEDAFRLIISRIKRIRQGEARGGRFMNPFLEGLVNSLARLTYVLAEDHEILAFCRDQNL
GSLFIDLLQVNGIDNVQIASARALKNLSSNSKNLTRKPEIPPPSYIESLFACFSKPPEIL
GLCPVHRGRCSVTETFCLVEGQAIEKLISLLDHTNENVVEASLAALSTLLDDGVDIEEGV
VILYKADGTKPILDVLVEKRTEDLRNRAVWVAERLLRVEKIAYEISNDQNVGTALVDAFQ
HGDYRTRQIAERALKHVDRIPNFSGIFPNNG
>Sgl17769 E3_adaptor/Cullin_RING/DCX/DWD 173.8 21.6
MVSITSTEINYLIFRYLHESGFTHSAFAFGYEAGINNSKIDGNLVPPGALVRFVQKGLQY
MELESNFSCSDADKDDDFSLLQPLDLITKDIDELQKIIKEKKESLCDHKHKEKEKEKEKD
HESENVRDRDKVKEKQTKEKAEQEKMRAQKDKEESKRKEKEKPQHNQVDVKPEDKSGIQN
EVNETPGAEPMDISMDTASLPLEIPSSDVKVLEGHTSEVFACAWSPAGSLLASGSGDSTA
RIWEIADGPSTSSMQNGLRNVVVLKHLKGRTNEKSKDVTTLDWNWDGTLLATGSYDGQAR
IWSKDGDLKSTLNKHKGPVFSLKWNKKGDYLLSGSVDKTAIVWDVKTGEWKQQFEFHTAP
TLDVDWRNNASFATCSTDNMIYVCNVGENRPVKSFSGHQGEVNAIKWDPAGALLASCSDD
CTAKVWSMKQDMYVHDLRGHEKEIYTIKWSPTGPGSSNPNQKPTLASASFDSTIKLWDVE
LGSLLCSLNGHRDPVYAVAFSPDGEYLASGSLDKCVNIWSVKEGKIVKTYTGNGGVFEVC
WNKEGDKIAACFANNVVCVLDVRM
>Sgl17770 E3_adaptor/Cullin_RING/DCX/DWD 158.8 20.1
MVLRLGTQELRNRGAEAVDISKDIASLHLKIPSSDVKILEGHKSEVCMCAWSPAGSLLAS
GSGDSTARIWDIADGPSTSSVNNGLLKVVVLKHLESRTKRNDVTALDWNLDGTLLATGSF
DGHASLWSKDGSLKSTLDKHQGPIFSLKWNKVGSYLLSGSVDKTAIVWDIRTREWKQRFE
FHTGPILDVDWRNSVSFATCSIDSMIYVCNIGEKRPLKSFCGHQGDVNAIKWDPNGTLLA
SCSDDCTAKVWSMKQNKYLHNLRGHEKEVYAIKWSPTGPGSSNPNKKLILASASFDSTIK
LWNAKSGGAVYTVAFSHDGEYLANGSSDNCVNIWSVKDGQLVKTYTGKGCVFEVCWNREG
NKVAACFANNVVCVLDIRM
>Sgl17788 E3_adaptor/Cullin_RING/SCF/F-box 11.8 0.0
MDKSIEMDSLIWSNLPEELLDRILCFLPFTTILNLRPTCKRFKSLLFSPFFLSNFYPSSS
SSSLVSSPFSCFLLLSHPHFNRHFPVYNSVSGVWRESSVSRSLLNPCSSSSSLLSSSNGL
LCFHLPRSSSFLVSNLLSRSSTLVKYPKLPFTFEFLNLVSYPNGFKIFIFSSKHVFLYDS
KHRSWKTFDGYEPILNDNIHHQGVYRDGRLYFTTSHPFSIVSFDLEKGIWGNFLDEMPFN
ELAFARLVMADNEGGNENKVYVIGGVGRNGISRCLKLWELAENLGSATESKSENAGKNTN
YSSWIEIESLPDLMYKKLVSVCYHNYEHIYCFWHNGLICICCYTWPEVLYYKVSRKTWHW
LPKCPSLPEKWSCGFRWFSFVPKLYASF
>Sgl17809 E3_adaptor/Cullin_RING/DCX/DWD 53.1 18.0
MLQQHTISSIDWKPSPITALATSVDDSQVAAAREDGSLEIWLVSPGSIGWHCQLTIHGDA
NSRISSLVWCRTSLKGSSSGRLFSASIDGSVHEWDLYQLKQKTVLESVGVSIWQMALEPM
KIILESVENVPHSNGNGVVVDYNSESSDDDSDDSVELCEDSSLENRRLALACDDGCVRLY
TIPDANQLTYHKSLPRVSGRALSVAWSSDGNSIYSGSSDGFVRCWDAKRMQELYRITVGL
GGLGSGSDLCVWSLLVLRCGVLVSADSTGSVQFWDSKHGTLLQAHSLHKGDAYALAAAPS
HNKVFSGGSDGKVILYKLSVDAADSSLNNMKSSEVRKRWVYVDSRSAHTHDVRALTLAVP
ISQEDLLPDEKVKKVRRKLKPVEFSYHKWANMGVPMLLSAGDDTRMFAYSANEFTKFAPH
DVCPAPQRVPLHFVQNSVFNKMPLLLVQTTNGVDIMSLKLKNGAILDKAPGGQASTSLLA
RVNNKGSGKITCSTISPSGSLFCFSNHVKPRLFELKRGEGSKTAWVIDKRQLPGKVPYAH
AMTFTSDSSRLIVAGSDRRIYIVDVESIAVLHVFTPCRKTQDEFSPPSEPPITKLFTSSD
GQWLAAVNCFGDIYVFNMEIQRQHWFLSRLDGASVTAGGFSPQSNNVFIITTSSNQVYAF
DVEAKQLGEWSRKNTPALPRRFQEFPGEVIGLSFPPSASSSTVVVYSSRAMCTIDFGLPV
EHDDSSDMVTTDMLNGLDSVSKKLLNSNGRLKRKLQQPDMYIKLYGRKNFEFCQFKHPVL
FVGHLSKSSLIVVDKPWLEVVKSFDSQPIHRHIYGT
>Sgl17822 E3_activity/RING/U-box 98.5 0.9
MPMYEPNKVEVSGGGQVIDLETAVKDGILGCGGVEEGGGGGFSYLSEKIELKKMVEELES
IEVPTVFICPISLEPMQDPVTLCTGQTYERSNIMKWLSLGRLTCPTTMQELWDESVTPNK
TLQQLIYTWFSQKYLVMKKKSEDVQGRVLEILENLKKVKGQTRVQALKLLKQIVGTHFSA
KKTMVDNGGVLFLSSLLGPFTSHAVGSEVVGILVNLGLGLEAKSNLTQPAKISLMVDMLN
EGSIETKINCTRLIQGLMEIKDFDPGLVSSLSLLVGLLKLVKDKRNSNGVQPGLSLLNMI
SSHECVRGSIISIGAIPQLVDVLPSLNAECLELALSVLDNLGSVEEGRLGLKDYPKTIPN
LVKLLMRTSEICTQLALSILWAVCKLCPEECAPIAVEAGLAAKLLLVIQSGCNPALKQQS
AELLKLCSLNYTATIFISKCKLTRTLQ
>Sgl17967 E3_adaptor/Cullin_RING/SCF/F-box 15.6 0.0
MAANGQGRNVSSKRPIKLNRFLTIDEHIIGEILKKLPAKDFAFAACVCRSWKRVSDETLS
ISKLVTGVSLKPKPLDAIKEAMQEVLSKPIRPQFVIANFTMGYNLPIVHDYVTKKEVSNE
YMDDYSSSDDSILPIFGLVLIKLSQVDGVDKFIDDVKTYSMEVSDSQSPAAILIFGMDER
IYMDDYYIGIEKKSAPKIINKDDASTSATPQMSSTSISLYSLQLDEDDGLESLVVKGKDI
KVGDSFEFYRADFERSLTMEGVVKPPNVQAHHPDAKVIGGLIFANMCETVEWMTRDPLAY
STPFIDQFGEDIPLGGLFTKHIVKRGSILSAWKDVEEQQIGDCSTGPKATQFLVMSFTPP
IPAPPPIIIED
>Sgl18117 E3_activity/RING/RING 22.2 0.1
MDSGNKVFTVDLLERHAAKGHGVVTCMAAGNDVTMWGTSKGWIIRHDFGIGDSYGIDLSG
GRTGDQSIHKVFVDQGGSHCIATMVGDGGPETFYIHAKWNKPRVLSKLKGLVVNAVAWNR
QHITEASTKEIILGTDNGQLHEMAVDEKDKREKYIKLLYELTELPEAFMGLQMETASIST
GTRYYVMAVTPRRLYSFTGIGSLESVFVSYHDRAVRFMELPGENVNSELHFFIKQKRAVH
FAWLSGAGIYHGDLNFGASHSSQDGDENFVENKALLDYPKLFDGAEVVKPSSLAISEFHF
LLLVGNKVKVVNRISEQIVEELHFDLSSESSSKGILGLCSDASAGLFYAYDQNSIFQVSV
NDEGRDMWKVYLDMKEYAAALANSRDALQRDQVYLAQAEAAVSTKDFLRAASFFAKINYI
LSFEEITLKFITANEQDALRVFLLWKLDSLSKDDKCQITMITTWTTELYLDKINRLLLED
NSTSADHNSEYRSLINEFRAFLSDSKDVLDEATTLKLLESYGRVDELVFFASLKGQYEIV
IHHYIQQGEVKKALEVLEKPRVSAHLLYKFASDLIMLDAYETIESWITKKDLNPRKLIPA
MLRYSSEPLAKNETHQVIRYLEHCVHGLNNEDPGIHNLLLSLYAKQEDESALLRFLQSKF
SNARQNWPEIFYDPKYALRLCLKEKKMCACVHIYSMMSMHEEAVALALLVDPDLAMAEAD
KVEDDEELRKKLWLMIAKHVVGQEKGTKRENIRKAIAFLKETDGLLKIEDILPFFPNFAL
IDDFREAICSSLEDYNKQIEHLKEEMNDATRGADNIRNDIGALAQRYAIIEHEEECGVCL
RRILNTYAAFGISRGYASVGPMAPFYVFPCGHAFHAQCLITHITRCTDPENGRHILDLQK
QLTLMSSETRRDSDGSLANEPVASTNQVDKISSQLDEAIASECPFCGELMIKEISLPFIL
SEEEEVNSWDIKPPNQKNISLSV
>Sgl18247 E3_adaptor/Cullin_RING/SCF/F-box 16.7 0.0
MKHSKHEESHLAELPVEVIKKILLRLPLKSLGKCKLVSKLWHSLISNPEFATFHLQFSNH
IGNSPSILALDRNKLISIATPKIDSSMDMITDGAPCLITLDREFNPPRRGHDCVFLVGSC
HGLVCLYLKKIRKPEDLMYLWNPTIDKHKHIPLPIEQGLTYVYARPSWFGFISSLNTYKI
FLVYKVHKQEYKYVCSLRDLKWREIREVGGKVGIPDLWKFKSVVMNEALHFLIGRECILR
FDLVAETFEKIPLSIKPDVLPRSCRMLLGVLRENTCLCALVIHWPQEWIFDLWILEEYNK
WDSWKKMYKIDLETNIGNDFGFIESGYYCVEGEKELVLIDPSHNPPLFVNVEKNGKTLYK
LTYHVESLVSSLCLP
>Sgl18363 E3_activity/RING/U-box 29.6 0.1
MAIGYRQSMSSVPSPNASCSSNNGSSGGGDASTFECNICFDLAQDPVVTLCGHLYCWPCL
YKWLHFHSMARDCPTCKASVQEEKLVPLYGRGKNSMDPRSKSIPGMNIPNRPTGQRPETA
RPHENNQFNQHGFGFMGGGVGVGGWGGFPPVATARVGNFALSTSFGGLIPYLFNFRMQGF
PDTPAYGAGVGYHPYGYANAFQGQDPHVHHIRRIQRQQEHILRMLFVVIILFLLFTFLSA
NN
>Sgl18419 E3_adaptor/Cullin_RING/DCX/DWD 20.8 0.5
MMTSVYGVTYIGARDQIKKRLKERALFSDDAELYGAACYTARDEKIRVFKWPSMDVLVDE
NEAYIEVKDLHSDGEHLVSVGNGGPCVNFIDGEHLVSVGNGGPCKIWDVASSKVVASLQK
ENDENFRFCRFSQSSERDQVLYTLTTRGKGVSIISWNTKSWNIIAAKHITRDPVSAFNVS
IDGKLLAMGHPDYKFIKDASPNDCEDGPYGTGVYPVMPEPPAIGGYEGVGEVYAVGSGVK
GLSPGD
>Sgl18434 UBD/UBC-like/UBD_UBC 91.8 0.0
MVFLRASRARLFKEYKEVQREKTADPDIQLACDDSNIFKWTALIKVSCISRNFELPYYLS
WSYLGIPYLQGPSETPYEGGVFQLAFAVPEQYPLQPPQVRFLTKIVHPNVHFKVRALRLV
RFAWSHAWTLQSVCRAIIALMAHPEPDSPLNCDSGNLLRSRDLRGFQSMAKMYTRLAATP
KKG
>Sgl18686 E3_adaptor/Cullin_RING/SCF/F-box 21.2 0.0
MGGAFRFSAATMVKKGRNSVSVGWCSRGFSRLFWVFWTIFCSNFVLVAESWLLHQIAMAL
SLQRYTLHDSDPTTSFNRLLKERVTKEKERSMLIAIEKLEHLPDNLIVEILSWLPVKDLL
QFKTVCKSWYSIISSPDFASKHLQNYCYNNNDTWRGCLLVQFSVPYAEHEVYELLVDETP
RVLGDEVLAYMPKFNSYVCGPCDGIYYMFHCCRRERALWNPAINEFRPLPTIISRPDLPA
NLTYENYEVYGFGLDPVTRDYKVVVVKGYWNTSNEEESHLNLPISVLVYSLRTNSWKYCG
DLRRYYNLEVNTSYICVNGCCYWFGSHDFGDEVVISFDLANDTFKEMDVPDHAQPSSKCL
GMYDDFLAFMSLHESEKNFDLWTLKEGYWTKKLSVGPFPDVWRLLGHSMDKKLILQCHDG
SLGFLDPDTQQIKDLAFQQRRRCEGAFAYMESLVSIKDKNAEEVEA
>Sgl18789 E3_adaptor/Cullin_RING/DCX/DWD 14.5 1.5
MTTVKSFFAKVYPHSVAWCLEMIVVWKLIRQHGTLPITSAEQEPDVMRTLVDVHSQECLE
YEAEIVFKLAGHQGSIFFLSWSDDGSKLVSVSDDRRKSPNLYSAGPVLFGHGARVWDCCI
SESQRKKEKSYLNWGDIPAATAEDVELAVAAARRAFKRNKGADWASASGAHRAKYLRAIA
AKAVFAGTLVNLVTLLSLHSIRVRVHRAKVTGQEVIIKVQRPGLKDLFDIDLKNLRLSGA
PSQLVKKASKKRPARPAIPSSQKGKRPKSGELKEEKKEEQREELSDQAFA
>Sgl19334 E3_activity/RING/RING 16.3 7.8
MECLHRFCRECIDKSMRMGNNECPACRTHCASRRFLRDDQRFDQLIAVLYPDIRKFEEEL
MYELEDVDLQKICYEVPSKRKKKVLLICLHISIIRIVLNDYFFAQIQESITQVLIKLSEA
LGKKRSSNKDAAGPSVTRSQQWCIPKDEGLKKKILEEAHNTPYSIHPGGDKLYKDLKQSF
WWPNMKREVAEFVAKCLTCQKVKIEHMRPGGKLQPLEIPSWKWESISMDFVMGLPNTKTS
KNAIWVVVDRLTKSARFIAMKDTWSLQQLADAYVKEVVRVAEGYSF
>Sgl19745 E3_adaptor/Cullin_RING/SCF/F-box 17.9 0.0
MSMNPELPEDIILIEILPRVPAKSLVKFKSVCRQWNTFISSVEFAKTHLHLHLHLHHPSF
LSSTKRSILTLGFSGDNRVFEAVDYSDADLNADSNNLYLTNFGKQFTALFKHLDLSASCN
GLAFLIASPAIKKHRLVNDYDRSYEFSYVIYNPVLGVGDYVEIRPPRRFPLGSVERGFID
MLISRHYNFGFGYDSKSDDYYIVAVSLVKDNGSPLFFESGWKLHVGTLVKETLHWAMSLG
HEKLILSYALATRNEAKTMYLPRPRFCNAI
>Sgl19798 E3_adaptor/Cullin_RING/SCF/F-box 21.5 0.0
MIKQGSRKRSLILLPPEEPPKNGLQEQVWLLHQIAMALSLQRYTLHDSDPTTNFNRLLKE
RVTKEKERSMLIAIEKLEHLPDNLIVEILSWLPVKDLLQFKTVCKSWYSIISSPDFASKH
LQNYCYNNNDTWRGCLLVQFSVPYAEHEVYELLVDETPRVLGDEVLAYMPKFNSYVCGPC
DGIYYMFHCCRRERALWNPAINEFRPLPTIISRPDLPANLTYENYEVYGFGLDPVTRDYK
VVVVKGYWNTSNEEESHLNLPISVLVYSLRTNSWKYCGDLRRYYNLEVNTSYICVNGCCY
WFGSHDFGDEVVISFDLANDTFKEMDVPDHAQPSSKCLGMYDDFLAFMSLHESEKNFDLW
TLKEGYWTKKLSVGPFPDVWRLLGHSMDKKLILQCHDGSLGFLDPDTQQIKDLAFQQRRR
CEGAFAYMESLVSIKDKNAEEVEA
>Sgl19821 E3_activity/RING/RING 19.9 4.6
MDQENPSSASVVEISLSDSDFSSDEEISEVIPAPGNLNASKNRLPSRAGSGGSGFHMQPG
PSFREGHHPRVLPHTLVHGELGSSGDNTTTSDPYQTYQTVGFGEENVLGNERIIFQAALQ
DLSQPRAELDVPQGILSVSLLRHQKIALAWMVEKETRTMHCMGGILADDQGLGKTISTIA
LIIKQLLAQLKSQLEKHDNDFAEALNLDDDDDDSTGDKKEDPNAGKCKSAEVCNSEPMLY
NLADDDDTGSGSTETVKKMENVDGLKSDSSSRSSSSLPKVQGKRPSAGTLIVCPATVLRQ
WARELSEKVAKKANLSVLLHHGSFRTKDPKILARYDVVLTTYAIVSNEVPEQPIIDEDDG
EQKTVDRFGLSSDFSVSKKRKHASTNKNGKKGKKAGPLARVNWFRVVLDEARIIQNHRTQ
TARACCRLRAKRRWCLSGAPIQNSVDEIYSYFKFLQHDLYSRYENFYYGIKNPISRDPTI
GYRKLQAVLKTLLLRRTKETLLDGEPIICLPPKTIEMKTINFSVEERSFYAQLEAESRSQ
FKAYAAAGTVNQNYANILLMILRLRQACDHPLLVKGFSSGPARKTNLESARNHPRHLLMG
LLNHLDTASAICQICSDSAEDAVVTICGHVYCYQCVADYLNGGDTLCPALRCKEKLSDDV
MFSESTLKCCLYGDVDVDGKSVNDNGCSKTPSILSNEYSSSKIKAALEILLAHHELNRKI
LEHDEFGSTSAGNSISAQVRIEKTENSSSKGPLKTIIFSQWTRMLDLFEYHLNHYCIPYR
RLDGSMSLAARDRAVREFNTIPEFTCILMSLKAGNLGLNMVAACHVILLDPLWNPAAEDQ
ALDQAHRIGQTQPLTVSRITIKDTVEDRILALQKEKRKMVASALGENHDASFGARLTMDD
LKYLFLGSLGI
>Sgl20242 E3_adaptor/Cullin_RING/DCX/DWD 187.1 38.8
MASLSYKKSYRRNQSLQQFYTGGPFAVSSDGTFLVCTCDDSIKIVDPSNASIKSTIEGDS
EPITALALSPDDKFLFSSSHSRQIRVWDLSTLECIRSMKGHDGPVMAMACDASGGLLATA
GADRKVIVWDIDGGFATHHFKGHKGVVTCIMFHLDHNRLLLFSGSDDATVRVWDLVAKKC
AATMEKHFSAVVSLAMSEDKNFLLSAGRDKVVNMWDLKSYGCKTTVPTYEVLEAVCVVSP
GTAFYDSLSSQKSKKSKSAGQDVYFLTVGERGIVRIWNSEGAVCVLEQKSSDVAFSPDEN
DLRRGFTAARMLPSDQGLLCVTADQQFLFYSFIKHSEEDLELGLSKRLIGYNEEIVDMKF
LGDDENFLAVATNLEQLRVYDLASMSCSYVLAGHTGTILCLDTCVTSSGVTLIVTGSKDN
SVRLWNPETRRCVGVGVGHTGAVGAVVCSKKWRNFFVSGSSDRTIKVWSFEGLDSDTEEP
ISLKAKAIVAAHDKDINSLAIAPFDSYVCSGSQDRTACIWKLPDLVSVAKLKGHKRGIWS
VEFSPVDKCVLTASGDKTIKMWALDGSCLKTFEGHTSSVLRAFFITRGTQFVSSGADGLL
KLWTVTSNECIATYDEHEDKVWALAIGKKTEVLATGGGDAVINVWNDSTAADKEEAFRKE
EEEVLRGQELANAVSDADYAQAIQIAFELRKPHKLYELLSELCRKKDAVDHLRKAVMPLG
KEEIQQLIEYIREWNTKPRLCHIAQFVLFQVFSMLSPTELVEVKGIRELLEGLIPYSQRH
FSRIDRLERSTFLLDYTLIGMSVIEPEPVRSDDAMQKKGSKKRKSKKSSDTERDASIMRL
FVQVGCEENVLGLGTWGSGVFMGERGLIMRMGSGVFMGSGASKSQKIVKLLMNECIISIC
TGGSNCLQNFFLCRAAYNENGSWCKELYNSS
>Sgl20255 E3_adaptor/Cullin_RING/DCX/DWD 55 6.9
MASLSYKKSYRRNQSLQQFYTGGPFAVSSDGTFLVCTCDDSIKIVDSSNASIKSTIEGDS
EPITALALSPDDKFLFSSSHSRQIRVWDLSTLECIRSMKGHDGPVMAMACDASGGLLATA
GADRKVIVWDIDGGFATHHFKGHKGVVTCIMFHLDHNRLLVSNKTNSFLTLNLFFISLLK
CLLL
>Sgl20396 E3_adaptor/Cullin_RING/SCF/F-box 19.5 2.6
MSFRSIVRDVRDGFGSLSRRSFEVRLSGHLRGKSHGSVHELHDPPIVIQNSKWASLPPEL
LRDVIKRLEASESTWPARKHVVACAAVCRSWRDMCKEIVRCPELSGKLTFPVSLKQPGPR
DGTIQCFIKRDKSNLTYHLFLCLSPALLVENGKFLLSAKRTRRTTCTEYVISMDADNISR
SSNTYIGKLRSNFLGTKFIIFDTQPPYNSSQSSPPGRSSRRFYSKKVSPKVPTGSYNIAQ
VTYELNVLGTRGPRRMHCIMQSIPNASLEPGGNVPGQPELLPRNLEDSFRSMSFSKSIDT
STEFSSSRFSDIAGPRDDDEEGGKEKPLVLRNKAPRWHEQLQCWCLNFRGRVTVASVKNF
QLIAATQPPPAGAPTPSQPAPSSSDHDKIILQFGKVGKDMFTMDYRYPLSAFQAFAICLS
SFDTKLACE
>Sgl20643 DUB/USP 118.6 3.4
MSECAASQHDDDGNSLIMLESYDPEETITIYEKSLSSNTFLLPLHCSSSKCQIIHWRQGH
KHECHPQDHSASEKDDFDENADSHRHDDVLDLPVPCLSTVTVASFDTGRSSCGENETLSS
HIDATKMGHREDKINSMEMNASTGLTPNGAVNSVRKLKKKSRQDDRRKFRPSNSEHSPGS
QQDKSNRTFGNVPSSKAEEVLLVDNDEQKHSSYSVPPRRSVSNELSRNGLASSFQKVVHH
FKASNQKKPSPHDNLLGISANRNLIARYAVDTMQSVCAELAGVVGPKRDESTLVGMTFGG
FLHSKIRCLKCNNKSEKYERMMDLTVEIDGDVRTLEQALRRFTASEMLEGDKKYYCNRCK
SYKKAKKKLTIFQAPNILTIVLKRFQAGSFAKLKKPVQFPEILNMTPYMSDSSDKDKHPQ
YNLYTVDP
>Sgl20764 E3_activity/RING/RING 16.1 16.7
MMDVRSLQQKPESGTDDATAEFERGLEELMRGHLDDCMSFTSCSSTRNTLDEDEDQEGDQ
LMRRRRRSDLAESSAARRRHSRILSRWAARQAQEMITTLERRNRESELMALAGLHPVSML
DYSFLRESQSQSQTLRRQGGTVERPSSRASAILQMWRELEDDHMLLNRARERVRERLSHG
SVVDSSTDVSTITTSEDREGENLGSVDDASESEHDFREWSHDQMQTRNDHVVSSSGEQSP
DLGEVERERVRQIARGWMESGTNERSSDITPRSNNNPREEWLGETERERVRVVREWVHMA
SQQRTRGGHDEDQRAVDSQADRVQGDVINSEEVEVQPEHVRRDILRLRGRQALIDLLMRI
EGERQRELQGLLEHRAVSDFAHRNRIQSFLRGRFLRTERITEDGRPPSVAASELLQLRQR
NTVSGLREGFHSRVETNIQGQERSDYVVSTGDRESGFPGDQAQQGNPDQLHPRIQGDGVT
ELANFVVNVPHEASANAITVEQSSIQRGNWQQQVAGDERRDLPQSNFAELDHSRSNPQEN
MVGDWQETPGNVMQRSTHLIDGEEESHLPGQQIWNDNGSRATQASWPGGWSNPPRIRRGI
PIRQINRFNRPDDDNVYSMELRELLSRRSVSTLLHSGFRESLDQLIQSYVERQGRASIDW
DLHRNLPVAAASLHDQDSQPVESNVSDTVNRRPLVIPSPPMPPLQPLWQQGLHQANWSRH
GMHRSELEWEMMNDLRADVARLQQGMNHMQKMLEACMDMQVELQRSVRQEVSAALNRSTG
GKGAETSEDGSRWGHVSKGTCCVCCDDYIDSLLYRCGHMCTCLKCANELVRGGGKCPLCR
APIVEVVRAYSIL
>Sgl20943 E3_adaptor/Cullin_RING/SCF/F-box 15.8 0.5
MDITPWISMLTQESKEGRYLNWQSSATYRPVILRIGNAHFIPASHSHAHQLSFSMLKRFP
PIFIEVEPAAITGLASSESENMSEHPTADSSPLVDAPRLSLPPGEKQVDHPTAVITTDEM
NFNPIDLITPVRVPGLKRWNFFPFPRPPGERTSDDLPPSDDPFDKSITSMPLDILHKIWS
HFTDETLSVGVVVCREWGQEIPEFIHHSPLMDPERRAALVDGWFPDFPLPSQYPPPYTLP
VQEGVSFCESSSDEEDEPETKYGPMRLPGHLPATWVEVNGVWGSDDEDVYIDQVAPTPVD
QACQEVAIDPNWYMNSDDGKEVQVLTRSGRLQNPDSQPPAPGNPQPPPQPPKEENPLIKQ
LQKVQTDISIWDLLTSSFEHRNKLLDALSQMNVAPDTTPDELVGLLTADHSRTTISFSED
DLPPEAINVCPLRTAETLGIDVSNITGTSQGVKAYDNTRRSSLGTVSLSIATGPVERRMT
FHVLDIKANFNLLLGRPWIHDLRAVPSSLHQKVKLIVGGKPITLEATPMSIYVNAIQVEH
DENDEDLWGFDAETAMVELAPSSALFTNPVKG
>Sgl21016 E3_adaptor/Cullin_RING/DCX/DWD 35.8 3.2
MGHRDKLKESSFRYKLPSLKFSCCNWLNQWLPPFRWLIAYRLLNLTEATIASGDDAGCVW
DTRQQSCCNTFQVHEEYISDMTFAPDLMKLLATSGDGTLSVCSLRSNKVHAQSEFCEDEP
LSVLIMKNGRKVVCGTQTRTLLLYSWGLFIDCSLVGILPNQIIQPIAEHSEYPVERLAFS
HEKKLLGSISHDNILKLWDMDGLLQGSNTVTRNDTTALDNDSNSDWMDVDSDLPKASKVC
IS
>Sgl21084 E3_adaptor/Cullin_RING/DCX/DWD 65 3.8
MGTMSLNHLDDDTVRSMSIGAVFSDFGGQINSIDFHRTSDLLVTASADDSVRLYDIVNAK
LLKTTYHKKHGADRICFTHHPSSVICSSKYNIDSTGESLRYLSMYDNRCLRYFKGHKERI
VSLSMSPINDSFMSGSLDHSVRMWDLRVNACQGILRLRGRPAVAYDQQGLVFAVAMEGGA
VKLFDSRSYDKGPFDTFLVGGDTAEVCDIKFSNDGKSMLLTTTNNHVYILDAYAGEKRCG
YSLEPSPNTTIEATFTPDGQYVVTGSGDGSMHAWNINMQSEVGRWSSHIGVASCLKWAPR
RVMFVAASSVLTFWIPYNGKNTGESNAKDADATDKMEVLPH
>Sgl21201 E3_activity/RING/RING 41.9 13.5
MLFLNRPLVGINATRRRRTYHFFWCRQCNKTIRIVSTISSTFICPFCYDLLFQELCPLRS
SIFPSHNFLLFLSSSSASHAQLIDTISRINNISSSQPRPTSIPPQESMLSIQHEPQTIEN
KTCLGITKFRIMSSDILCFEQTCPICKEDFVVDEQITKLGCNHLYHSVCISPWLQINMTC
PLCRYKLPTHQGCSQHDHNNRARRSSNNFRVLTQLFSFLWPFRLGSYLDRLFPS
>Sgl21341 DUB/USP 44.7 0.1
MASTSWDHSQPLPKTDDEERLWGTSFLMLPEFFNLTVLTLESRAWPWQEQAIPHPTSFHP
SSVAFLDSWILRVRRSRRSTLMLFAGGGGTSTSGNPNVQRSIREECVMSQNSTLFNGASR
FQNLCELVDCSNGICEHDPIRLCCNNGSKKADFCDYDYNLIYLQDIYVSHGKKSSVELEK
ALVLEDAISDLPEVSTYEKQDERPYEGAPLSEFQRYIRLNKKEQAKVELDPSMERVFLPS
NKPLTTTKKKITSAFSFPEELDMGFRLAEPSESALVYGLSAVLVHKGTAVNSGHYVAHIK
DESSGH
>Sgl21372 E3_activity/RING/RING 17.1 16.7
MLITFLLSICWFVNDVSIDHVLLSFLRGRFLRTERITEDGRPPSVAASELLQLRQRNTVS
GLREGFHSRVETNIQGQERSDYVVSTGDRESGFPGDQAQQGNPDQLHPRIQGDGVTELAN
FVVNVPHEASANAITVEQSSIQRGNWQQQVAGDERRDLPQSNFAELDHSRSNPQENMVGD
WQETPGNVMQRSTHLIDGEEESHLPGQQIWNDNGSRATQASWPGGWSNPPRIRRGIPIRQ
INRFNRPDDDNVYSMELRELLSRRSVSTLLHSGFRESLDQLIQSYVERQGRASIDWDLHR
NLPVAAASLHDQDSQPVESNVSDTVNRRPLVIPSPPMPPPQPLWQQGLHQANWSRHGMHR
SELEWEMMNDLRADVARLQQGMNHMQKMLEACMDMQVELQRSVRQEVSAALNRSTGGKGA
ETSEDGSRWGHVSKGTCCVCCDDYIDSLLYRCGHMCTCLKCANELVRGGGKCPLCRAPIV
EVVRPYSIL
>Sgl22275 DUB/USP 277.1 2.1
MAFLQMNWQPNHHHHKRKYAAPLGLKNLGNSCYLNSVLQCLTYTPPLANFCLDYRHSSFC
DLASDPERKRDCPFCIIEKRIVRSLSIDLTLDTPSRLVNCLRIFAEHFKCGRQEDAHEFL
RYVIDACHNTCLRLKKLQLQRAKKITNGSGGETSGGNTIVKEIFGGSLQSQVKCLSCGTE
SNKVDDIMDICLEISNCSSLKDAMKKFFQSEILDGNNKYKCDRCKKLVEAKKQMSILQAP
NVLVVQLKRFEGIFGGKIDRVIAFEEILVLSSFMCKASQDPHPEYSLFATIVHSGYSPES
GHYYAYIKDATGRWYCCNDSFVTLSTLQEVLSEKAYILFFTRTGQRPVSADTEVMSNGIK
PSETNGSNMSKSPMKTMNLKSSNAPSLVKGISVASKNSDAVILQNKFSGIANSLAKRVSG
SDNGITDILKRESAGVNGNSKNSLAKQLNVEKTHSSQDNNGNCRNGEHSDNENHRNGEHS
DNGNHRNGEHKENGNHRNGEHKENGNRRNEEHNDNKNCRNGESNAVASSQVIVNGGTHLK
NGTLGLVKGRIHENNGLENKDTTGMLLDNGTIHNGHSADCVDASGPKRKLENRETADKIL
ENGQSHKSSDVSSSKRRFEDRDTCILLAKDAQSRSRVEEFKEFLKKEAALLLQTCGWSDD
VYKYMRSKKRARNDACSSIDNSEQKKMLIADAKTTFISQVPGSLKGSLIEHIRSFSNQK
>Sgl22314 DUB/USP 276.8 2.0
MAFLQMNWQPNHHHHKRKYAAPLGLKNLGNSCYLNSVLQCLTYTPPLANFCLDYRHSSFC
DLASDPERKRDCPFCIIEKRIVRSLSIDLTLDTPSRLVNCLRIFAEHFKCGRQEDAHEFL
RYVIDACHNTCLRLKKLQLQRAKKITNGSGGETSGGNTIVKEIFGGSLQSQVKCLSCGTE
SNKVDDIMDICLEISNCSSLKDAMKKFFQSEILDGNNKYKCERCKKLVEAKKQMSILQAP
NVLVVQLKRFEGIFGGKIDRVIAFEEILVLSSFLCKASQDPHPEYSLFATIVHSGYSPES
GHYYAYIKDAAGRWYCCNDSFVTLSTLQEVLSEKAYILFFTRTGQRPVSADTEVMSNGIK
PSETNGSNMSKSPMKTMNLKSSNAPSLVKGISVASKNSDAVILQNKFSGITNSLAKRVSG
SDNGITDILKRESAGVDGNSKNSVAKRLNVEKTHSSEDSNGNCRNGEHSDNENHRNGEHS
DNGNRRNGEHKENGNHRNGEHKENGNRRNEEHNDNKNCRNGESNAVASSQVIVNGGTHLK
NGTLGLVKGSIHENNGTGMLLDNGTIHNGHSADCVDASGPKRKLENRETADKILENGQSH
KSSDVSSSKRRFEDRGTCILLAKDAQSQSRVEEFKEFLKKEAALLLQTCGWSDDVYKYMR
SKKRVHNDACSSIDNSEQK
>Sgl22341 E3_adaptor/Cullin_RING/DCX/DWD 31.1 0.2
MASGLCKGRFMNEVESLCGHTTPVESLAFDSAEVLVLGGASSGTVKLWDLEEAKSEFVYV
LHFIYPPFVRWVVSGGFDNVVKLQLQPSQVNYHSDLVSVRVTLSMSVILRETRLGKGKGN
AGGSSQKGGAEEEKYWDLSGLSLKGTLAPELGILHTNHLSGVIPAEFGRLTKLEVLDLSD
NNFTGVIPTDIAKIVSLKRLLLCGNNFEGIIPPEFEEYSSLIAVSLKFDLKT
>Sgl22375 DUB/USP 258.9 0.0
MLEPRQADIPALFLVLVVLPVVLYILLGKWSEASNKKERINLVVEEAFVESFRPDVMAAV
SVIPPVVPPLSTSFRECARCHGPATTRCARCKSIRYCSGRCQIIHWRQGHKEQCQPPDDI
YSSSNSASVEEADSETDFNQKGVYHQFNGCPSQFPGANSTGASPADTSAFVDACQMLKHE
RTISEKRVSRKAKELLDTENEAYSRPKLRVGNSTNTEDGLSEIDCISGSVTCDKYTGRRG
ALQQSPGVISQTKHSPPSAESGMNVKEIASSYREANCNAKVSKRSNLSQMVSNCEDIGSR
SPIASDSAKSMPRASREQIKLEKARKGNGLGKSVHGMGNFTSTHETNSIASVGLVKAAGV
KKSSKITKNAASDMVINNWKKVKVLFPFEEFTKFFEIEVFNLVPKGLLNCGNSCYANAVL
QCLTCTKPLVVYLLGQTHSRTCSLNTWCLMCELEQHVHMLRDTAGPLSPSRILSHIRSIN
CQIGDGSQEDAHEFLRLLVASMQSICLEEAGGENLIHPILQETTFVQQTFGGRLRSMVVC
LRCHHESERYENILDLTLEIFGWVESLEDALTQFTTPEDLDGENMYRCGRCTTYVRARKQ
LSIDEAPNILTIVLKRFQEGSYGKLNKCITFPEMLDMIPFMTGINDSPPLYMLYGVVVHV
DTLNASFSGHYVSYVKDLQGNWFRIDDTVVQPVPMSQVMSEGAYILFYMRSFPRPPRAFI
KNARKQQQTVKSSRSCVSKTQSSSKKGLDIHRSDSRFNQAMETRTYPDFMEFSDATTSDW
SLFTSSDEASFTSESTRDSFSTTDYIENGNVDPFSSMFGTHSTRDHQSSQRMVSCSMFSG
SKPVTRYVSEQTGYVLDSDHAVYPLDEMQMGDIMSQVSVPFNEAYLPNSEYQNFVNYEST
ASDSFIQTFTNVHL
>Sgl22378 E3_activity/RING/RING 10.5 13.6
MGNKLGRRKQVVDEKYTRPQGLYQIKDVDYKKLRKLILESKLAPCFPGGDDCDTGILEEC
PICFLYYPTLNRSRCCTKSICTECFLQMKNPNSTRPTQCPFCKTSNYAVEYRGEKSKEEK
GMEQIEEQKFIEAKIRMRQQQQLQLEEESNHRTEDTLSHMDPRTENIGCSTIGGIECEES
APSLDSSGAQMFRQPQNTRHGRDDEFDLDLEDIMVMEAIWLSVKENERGGHLPYGDALPE
PYTVEDHYMSSAAAPVTRSSTSPSGGLACAIAALAERQQLTGESSSNNYSGPISPLDMLP
SSSSRSSKRMKKTQRKPTEISSTEEICSSRVLADACEVGPASEIAEVGPSYVDSDDSDSE
AVILAPPPPPYRGRWNSKRGKNIQRKLSKNMHGRRMVAEEWEYDRVAEAGTTRANSDDSD
EDLQAAILPPPPPPLPPYEMIGSSSGSCGAQDHGDYLLPPPPLPYVSDCGFQSSVPGPIV
PENFEEQMMLAMAVSLADSRTRTTAQGVTWH
>Sgl22588 E3_adaptor/Cullin_RING/SCF/F-box 17.4 0.0
MKKVRRSSRLERRGVTMKSEDMQNYCPFENIASDVIMKVFSFLPTKACLKCKLVCKAWYD
IITNREFANQRRAHGCYRSLLLQGRFSGSRKEFVLLDLDRSSKVVEEGNLTVGYLATLTI
KPNFGIPMGKLHLINECNGLICLKVSARWSPFIICNLLTGQQWTVKQTYKPNAFIYSCGL
GHFLRSDDSGQFKDYFKVLRILVSRKERCYVAEIQTLGTNEWRSVGKVPKVELGKAFLHG
SLHGYSNEDNCIWSFDCGEEKFSPVPLSDELKRKKVTGVSTLDSFLCCKTTTSGKEDLCE
IWIMKEYGNKDSWVKQFSFSLVKHSSDDGMPFLRMDSGEVMFRNPVVGCNYRSFLTVRDL
ESKTHMCVRFISDNPSEYCTSFGKYILNS
>Sgl22686 E3_adaptor/Cullin_RING/DCX/DWD 111 6.9
MFDTRNMMHSDPSMPKMTDESDYSDRPSSFSAMGNSFIDEPTRMSAEMSPMMMSPWNQVS
PFAKSHWSQTSDNPSFGDSGQLNSLIGSLVREEGHIYSLATKGDLLYTGSDSKNIRVWKN
LKEFSGFKSASGLVKAIVIAGGKIFTGHQDGKIRVWKVSPKNPSIHKRSGSLPTLKDLFK
ASIKPSSYVEVKRHRSSLWIKHSDAISCLSMSGEQGILYSSSWDRTFKVWRISDSKCLES
VSAHEDAVNSVVASSEGMVFTGSADGSVKVWRREMQGKVTKHFFVQTLLKQECAVTALAV
DPTGSIVYCGSSDGMVNFWEREKNLAHGGVLRGHKLAVLCLAARARLVFTGSADKTICVW
RREGTIHTCLSVLTGHSGPVKCLAVEDDKDAVGQRYVVYSGSLDKSVKVWNVADQEAMGM
GIGMGMGMGMMPQQQQVMEVDSASESLRSDRSSQYT
>Sgl22711 E3_adaptor/Cullin_RING/SCF/F-box 18.7 0.0
MKKVRRASRLERRGVTMKNEDMQNYCPFENIASDVIMKIFSFLPTKACLKCKLVCKAWYD
IITNREFANQRRAHGCYRSLLLQGRFSGSRKEFVLLDLDRSSKVVEEGNLSVGYLATLTI
KPNFGIPMGKLHLINECNGLICLKVSARWSPFIICNLLTGQQWTVKQTYKPNAFIYSCGL
GHFLRSDDSGQFKDYFKVLRILVSRKERCYVAEIQTLGTNEWRSVGKVPKVELGKAFLHG
SLHGYSNEDNCIWSFDCGEEKFSPVPLSDELKRKKVTGVSTLDSFLCCKTTTSGKEDLCE
IWIMKEYGNKDSWVKQFSFSLVKHSSDDGMPFLRMDSGEVMFRNPVVGCNYRSFLIVRDL
ESKTHMCVRFISDNPSEYCTSFGKYILNS
>Sgl22749 E3_adaptor/Cullin_RING/SCF/F-box 16 0.1
MSSLGEKERKLIMIEDLDDYMLIEILIRLPSRSVYQCKSVCNRWLSLISCPYFKQRYDSL
YDRKNIIHVLATVTGGSNDHPQYQKDGIIVTNKSTKEVDNQMLLQFSWKTGSQTQQLESK
HVLFVSDDLFLYRSNPGELMICSLLTRQSRTLPSPPPFHCNYFMGCLRSNVDPSQYKVVL
VQQRDDFNAQDEIYKFLDLAVFPCNDGNWSMFSVLAPQNIGFRVMKWVDISQYATSCNGM
LYWATNNMIVGYDPFNNANECEFIEFPDQSIISCACITNVQGCIRLYDSEVTSSSTITLW
DLNDHKGRIWSKKHIDLSGVNWHQISSLQPVRLSIKGFNPIDGDVMFILLSNSVIFAINL
TSKTEHVLQDYKPSSTQIIFDFRPCTEILSRLFLIGLLPWPVPLP
>Sgl22751 E3_adaptor/Cullin_RING/DCX/DWD 133 14.4
MLGPYPKEKLGLTRNFCNFLLTPIFCNFSLPGADIVHLYYSGAGKMLAMPNNNESALSVA
GPRPMEWSTVPYSGSQAPGTNGRQRTSSLESPIMLLTGHQSAVYTMKFNPEGTVIASGSH
DREIFLWNVHGDCKNFMVMKGHKNAVLDLHWTTDGTQVVSASPDKTVRAWDAETGKQIKK
MAEHSSFVNSCCPARRGPPLVVSGSDDGTAKLWDMRHRGAIQTFPDKYQITAVCFSDASD
KVYTGGIDNDVKVWDVRKNEVTMTLQGHQDMITGMSLSADGSYLLTNGMDCKLCIWDMRP
YAPQNRCVKVLEGHQHNFEKNLLKCAWAPDGSKVSAGSADRMVYIWDTTSRRILYKLPGH
TGSVNECVFHPREPILGSCSSDKQIYLGEL
>Sgl22753 E3_adaptor/Cullin_RING/DCX/DWD 132.8 14.8
MIKLMRMDWALDEVSRAAVLLSCIVVPYSGSQAPGTNGRQRTSSLESPIMLLTGHQSAVY
TMKFNPEGTVIASGSHDREIFLWNVHGDCKNFMVMKGHKNAVLDLHWTTDGTQVVSASPD
KTVRAWDAETGKQIKKMAEHSSFVNSCCPARRGPPLVVSGSDDGTAKLWDMRHRGAIQTF
PDKYQITAVCFSDASDKVYTGGIDNDVKVWDVRKNEVTMTLQGHQDMITGMSLSADGSYL
LTNGMDCKLCIWDMRPYAPQNRCVKVLEGHQHNFEKNLLKCAWAPDGSKVSAGSADRMVY
IWDTTSRRILYKLPGHTGSVNECVFHPREPIVGSCSSDKQIYLGEL
>Sgl22810 ULD/UDP/UBQ/UBQ_PIM 540.4 23.4
MQIFVKTLTGKTITLEVESSDTIDNVKTKIQDKEGIPPDQQRLIFAGKQLEDGRTLADYN
IQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVESSDTIDNVKAKIQDKEGIPPDQQRLI
FAGKQLEDGRTLADYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVESSDTIDNVKA
KIQDKEGIPQTSRGQGRYPPDQQRLIFAGKQLEDGRTLADYNIQKESTLHLVLRLRGGMQ
IFVKTLTGKTITLEVESSDTIDNVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLADYNIQ
KESTLHLVLRLRGGMQIFVKTLTGKTITLEVESSDTIDNVKAKIQDKEGIPPDQQRLIFA
GKQLEDGRTLADYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVESSDTIDNVKAKI
QDKEGIPPDQQRLIFAGKQLEDGRTLADYNIQKESTLHLVLRLRGGL
>Sgl22862 E3_adaptor/Cullin_RING/DCX/DWD 15.5 1.1
MAMFKQGGWYGHGAIFSSIIIGSIFLCFFLQSSTAEQVNLTVEKFTVFGIAEKSNDNNTV
HFDLKMRNYNIRPIYYDALNITFYFKSNLSNSPIGNATFASFRLRKNRQDHLVGSFKAIG
MKWENATAPLAMFRVQVASAMRFGLKNNFFKSKRFRYVIKADLKVDNQGNLVNKGVELKS
SVGRNVKGPFEMIGILLGLKVNHSLFWVGSLELSDVLLQACLHVMWITDHYMVYLFYQSV
DSEIVLWEPIIKEHSPGEGSVDILQKYPVPDCDIWFIKFSCDFHYKAGNREGRIYVWELQ
SCPPVLITKLSHPYSKSPIRQTAMSFDGSTILACCEDGTIWRWM
>Sgl22945 E3_adaptor/Cullin_RING/DCX/DWD 96.9 8.4
MDLLCKSYSNNSDNDEEDDRPSQNIQPPLKRQKPLYPKPYFQVSDSQIRVSNSRIGAPDS
QMGAPVSGNGRYISKREKALMASSSSSSTNDVNYPTSFPPSTEMGSISRAHVRQDILLSL
RKQTTTFARKDKLPCKLSTDLHGHLKPVNSVQWSTNHAHLLASAGMDNCVYIWNVWSEQQ
KKVRAFRHHNAAVKDVKWSPEGKFILSCGYDCSSRLIDVEKGSETQSFTENQAVTAIKFH
PHNSNLFLSGGSKGFLKLWDIRAGKVVHEYVRRLGPILDVEFMSDGKQFISSSDVSQSNL
SENSLIVWDVSREVPLSNQVYVEAFTCPCVRCHPFETSFVAQSNGNYIAIFSTKHPFRLD
KYRRYESHGVFGFPIKCCFNMDGEILASGSSDGEIHLYSVRSSSLLKKIKVYSQPCIDVA
FHPVIPNVIACCSWSGNVSVIE
>Sgl22969 DUB/USP 149.3 0.0
MRCVMKWRAPPVGWIKLNVDAYVMENVGVGLGVVARDEEGKFVFLAVKRLRVKWEASWAE
AAAVRYGIEVAQRMGIHKVIMESDSLEVVTAVKQRNGGMALFFTFVEDIIELSSGFTSLD
FNHVKREGNTVAHLMARTKLGHGMLSGRYSIPSSEKQEGIPPRMFKTVIAASHPEFSTMR
QQDALEFFLHLLEQVERVNVGNPKLDPSRNFKFGIEDRIQCPSGKVNYNRRCDYILSLNI
PLSEATNKDQLEAFQKLKSQAELDGKDIDTSEVVRPRVPLEACLASFSAPEEVMDFYSTA
LKAKTTAKKTTGLTSFPDYLVLHMRKFVMEDGWVPKKLDVYIDVPDIIDISHMRSSGLQF
GEELLPESADDEAEATKILANQEIVSQLLSMGFGQIPCEKAAINTGNVGVEEAMNWMLSH
MDDPDINDPISSHTSQNAAASVDQSKVDTLISFGFQDEVARKALMASGGDIEKATDWIFS
NPNALSTSDMDTSSSSAVAADAELPDGSGKYRLLGFVSHMGTSTHCGHYVAHVYKDGKWV
LYNDEKVGASVNPPKDMGYLYFFERVTG
>Sgl23056 E3_adaptor/Cullin_RING/DCX/DWD 84.7 16.8
MSKNTEQEQEEEEEEEEKEDYTNHHRNEIDTIATSPRRHRTYHSHYHRSHCNSSSSSNEK
GKHNSGVPKFPMSAQNYDVWVSSESFSLSSLEQRRDRLLKALGLSSDTGLARRRSGAVRS
VSFDHHFGGCSTELPTKFEDDGFINRSKSDQCNSSAYSSSCSSILSIRSVCDTVNRDSKS
YNKYNVDVGVNYIDSKNNKNNNYDDKCSNGVVVVDNLVSNGCIGPVSVSGLGGLDKSEAV
RSGSSDGIGAVEGGCGGGEKICKSGGQVDEFESDKVCTIKNLDTGKEFVVKEVREDGMWN
KLKEVGTGRHLTMEEFEMCVGHSPIVQELMRRQNVEDQLNNGKDNGDCNGNGDNGSKSKK
KLSWFKSIKNVASSVAGYKDRRSSDDRDTSSEKGGRRSSSATDDSQDTTFHGPERVRVRQ
YGKSVKDLTALFKSQEIQAHNGSIWTIKFSLDGRFLASAGEDCVIHVWQVVESERKGELL
MDKPDDASLSLFLMPSGSPEPNSVSSSLDNPLEKKRRGRPSISRKSVSLDPVRVPEIIFG
LSEKPICSFQGHSDDVLDLSWSKSQLLLSSSMDKTVRLWNLSSKTCLKIFSHSDYVTCIQ
FNPVDDRYFISGSLDAKVRIWSIPDRQVVDWSDLHEMVTAACYTPDGQGALVGSYKGSCR
LYNTSENKLQQKCQINLQNKKKKSHLKKITGFQFAPGSSSEVLITSADSRVRVVDGSDLV
HKFKGFRNTNSQISASLTTNGKYVVCASEDSHVYVWKHEAESRPSRSKGVTVTRSYEHFH
CQDVSVAIPWPGIGELLGPQELCSEEQTEVHHPLDEVLTVNHPPTPVEEFNGNDSSPSAS
GRSNSPFRGTISSAPNSYFFDRISSTWPEEKLLAAKNRSPRVSLDLSNGMLQNRAAWRMV
IITAGLRGEIRTFQNFGLPVRI
>Sgl23132 E3_activity/RING/RING 39.2 6.4
MAFIGAPQPWLSPSPSSTPPPPFNAFDDKNEDCSLPLCSNKCPQFCLVLPPPPPFVFNNN
PSYDYDDDDSPYRISPLMVALISVLSAAFLILFYYTVISRLCRNHRRRHNNNRLLNPNHV
DSLIPDQTQPETAATSGLDDSFIQKIPVFNFRKSDKLIDATECAICLSEFDEEENLRLMP
NCEHAFHIHCIDEWLKSNSNCPLCRSSMNPPPVSSISVLYSI
>Sgl23160 E3_activity/RING/RING 32.8 8.2
MDKSYNGELFYIAGIGLFLNLFLFATTLIIYLCKPRNENTDLESFDHVQYYYEDDHLSVP
LLDEEEEEKGLRLINCIPSMKFIQVSKGEDEESSRANGCSICLIEGYEDDEMIKVLPECN
HVFHSCCIDQWLKKKQSCPVCRKVFRVVLPKV
>Sgl23162 E2/UBC 79.4 0.0
MKTDANIIGDSEETLFAASYSYYSIPLLAILESKHSKKIRKSFLDESSSSSYNKPNIVAI
HSESELSEQISVGGHEIILVDEEQHDNVVIVDEKDASFGSNTIVGHEVVAVDEDDAVVFD
EKDAFNDKGKKLLVNKFAGQEVDTPDEVIPSPQASEIVEAEAMAPKLSASASTSAAREKH
AVPETSCFKEDHPKAMKSKSFFKSLFSKRCFMPKFACFGSKLRSFNRRASASHVEMHASP
STFAAVQTPPIAEAGDVHFHLDQGLKLDDFHPNSAEFPPPSTDGQSNSSQDSILKKLELF
KNFDISEDHFGHSFEVINECSNPSNEWVKYIADEWKMLQIGLPDAIYVRVYEARMDLLRA
VIIGANGTPYHDGLFCFDIQFPSSYPKVPPAVKYHSHGLKINPILRPSGDVCLSLLLSTS
DVVENEYWRPYQSNMLQVLVSIQGLVLNAEPFSDDPDVPSNQTSHKTRSENTYIDSLKSM
LYTLRSPPKGFEDLVQGHFYMHAHDILEACRAYLDGVEVGSYVKGNPQATASENIENCSE
YLNMMLPHYINLLVKAFTKIGVKDCEKYSIPEEFF
>Sgl23163 E2/UBC 93 0.0
MEDPTIQLHPLPNSRKRKFASSGSSSNSSMVEPDLIEIPPPATWKSKPQKQKSVAGCELI
VLDDAEDTDDVIVIDEKIAPKSKGKKPMHNYLSGDSIPANNGPLSASVKDSMNGASSSGV
SFIDDSFDFAGMDLAGSHYDSECALLQAHFDSIDIPSGVEATVPWWAFSPEIIEPPVIPS
SSAAITNQSNSFVDTSEVDGFQSWAYSPGIVEHSVIPSSSVGISNHSNSVVETSEVDRFQ
PLGKVKPVSFKKKTASKKFLHGSKHPFSGHATYPMPYAQTSGMFPPHNGWPSVPGQGPNF
AFDHDPFGSKGFPGWQNASHVYPSPVPFLSSVASSNSISKLSNGNMHVPQFLDPVRLDDG
ISSQISPPFSQEQGDGSENSIVKKLEVFKKFDTLEDHSDHFFLKNKESGSQAKNSWLRKL
ADEWKMLERDLPGTIYVRVYEARMDLLRAVIVGADGTPYHDGLFFFDVHFPPTYPHKAPS
VNYHAHGLRLNPNLYNCGKVCLSLLGTWSGSGVENWLPGKSNMLQVLLSIQGLILNAEPY
YNEPGFANSKGNQHGRQQSKNYSENTFLLSLKTMLYTMRNPPKHFEDLVFGHFYTRAHDI
LGACRAYLCGVEVGSYEKSKPAARSKGSNCSQLLLKNLPTYIKSLVEAFTKIGVKDCEKF
LVPVENVANQPARGSSASRAKGRKFLASYVPPWNHV
>Sgl23184 E3_adaptor/Cullin_RING/DCX/DWD 97.3 14.3
MEGSSNTGWRKSASSRGLETSVSSERNLRLLHASRRSLSTDASRNAFGSGRSTKDAAIGQ
SPSDYLRNRLGSSGVSEDEVAMDPVVRSIEWGDVSLRQWLDNPERSVDTIESLHIFRQIV
EIVSTAHSQGIVLNNVRPSCFIMSSFNHISFIESASCSDSGSDSLEDGMDGQNTETKQPC
SSLCHDLPEQRSRSAHKDTHLMTETSGSKSHSLLATNVASTEERGWCEAKDSRCSRKAGE
KQSFPMKELLLMETSWYTSPEEIAGAPCSCASDIYRLGVLLFELFCTFSSFEEKSGTMSS
LRHRVLPPQILLKCPKEASFCLWLLHPDPCSRPKMSDLLQSEFFNEPRDDIVEREAAIEL
REKLEEHELLLEFLVLMRQAKQDAANKLHNTISFLSTDIEEIVNKQKAIKQKGGTFSGPE
RSHQSELDLPPINTSEHEMDHTDTGQGTQIHGVSKFSFDQSESQSQESLLSKNSRLIKNF
KKLESAYLLTRHRPARMSGKPVGGHSHLSSNSRGSVVLNEKSSSVSLSKECKNNSGESGW
ISPFLDGLCKYLQYTKLDAKADLKQGDLLNSSNLVCSVSFDRDGEFFATAGVNKKIKVFE
CDTLLSGDHDIHYPVVEMACRSKLSSICWNSYIKSQIASSNFDGVVQVWDAARGQVFMEL
KEHERRVWSVDFSSADPTLLASGSDDGSVKLWSINQGASIGTIKTKANVCCVQFPSDSGR
TLAFGSADHKIYYYDLRNPRVPLCTLIGHNKTVSYIKFVDSSTLVSASTDSTLKLWDLTN
CASRVVEGPLQSFTGHANVKNFVGLSVSDGYIATGSETNEVFIYHKAFPMPALSYKFNTV
DPLSGNETDDGAQFISSVCWRAQSPMVVAANSTGDIKLLEMV
>Sgl23194 E3_adaptor/Cullin_RING/SCF/F-box 14.4 0.0
MWADLPRDILFDIVRYIDMKVDLPRVRGVCRSWRTALNLDELPRRDPHTIEVPNLEGIEI
ECYLRINSSPLFLLESRFYFISPVISSESAGTSNCNRGGWIARMCEAKTETGTGINNRWH
LLNPLRNNGTYYHENIEYLYVEPPITGTINMLDFRVLELARSYSLVNDKDNYNATDLSKK
VVGGWDYTSSYRFAALVQPDFKGHLLLLWRLGDQQWLKVVGKDVLRILDIAFLKGKFYVL
EQLFDQQRRVRVLNPQNPLVLLESTISVPDILLPSPKHMSGVDNGVSPFRNTFNLLPSKS
KGCLYLVLEDFLNEGNTEGGRPRFGSKIMFLVLMMENERKWKEMENIGDEIFFIGLDVAF
ALPSSSQNLPHWKQNSICFAVDQEYYSLDVYTRRTEVPGAECLDYVIYQTYNNCWSLFSL
EEKEKGDVPFDEMPKEEQELYLGLFFPPPAWVKWRCPTLDNVEVRLDGLRFPFQKRKKDG
LSFHEEEQQQEENSDD
>Sgl23197 E3_adaptor/Cullin_RING/DCX/DWD 97.3 14.3
MEGSSNSGWRKSASSRGLETSVSSERNLRLLHASRRSLSTDASRNAFGSGRSTKDAAIGQ
SPSDYLRNRLGSSGVSEDEVAMDPVVRSIEWGDVSLRQWLDNPERSVDTIESLHIFRQIV
EIVSTAHSQGIVLNNVRPSCFIMSSFNHISFIESASCSDSGSDSLEDGMDGQNTETKQPC
SSLCHDLPEQRSRSAHKDTQLMTETSGSKSHSLLATNVASTEERGWCEAKDSRCSRKAGE
KQSFPMKELLLMETSWYTSPEEIAGAPCSCASDIYRLGVLLFELFCTFSSFEEKSGTMSS
LRHRVLPPQILLKCPKEASFCLWLLHPDPCSRPKMSDLLQSEFFNEPRDDIVEREAAIEL
REKLEEHELLLEFLVLMRQAKQDAANKLHNTISFLSTDIEEIVNKQKAIKQKGGTFSGPE
RSHQSELDLPPINTSEHEMDHTDTGQRTQIHGVSKFSFDQSESQSQESLLSKNSRLIKNF
KKLESAYLLTRHRPARMSGKPVGGHSHLSSNSRGSVVLNEKSSSVSLSKECKNNSGESGW
ISPFLDGLCKYLQYTKLDAKADLKQGDLLNSSNLVCSVSFDRDGEFFATAGVNKKIKVFE
CDTLLSGDRDIHYPVVEMACRSKLSSICWNSYIKSQIASSNFDGVVQVWDAARGQVFMEL
KEHERRVWSVDFSSADPTLLASGSDDGSVKLWSINQGASIGTIKTKANVCCVQFPSDSGR
TLAFGSADHKIYYYDLRNPRVPLCTLIGHNKTVSYIKFVDSSTLVSASTDSTLKLWDLTN
CASRVVEGPLQSFTGHANVKNFVGLSVSDGYIATGSETNEVFIYHKAFPMPALSYKFNTV
DPLSGNETDDGAQFISSVCWRAQSPMVVAANSTGDIKLLEMV
>Sgl23242 E3_adaptor/Cullin_RING/SCF/F-box 22 0.0
MEAAFNPSIALPFPYSNYGITNVPTFNPSFPHHHQTTTITSLLPPFFTTTTTPTTTSTTT
TINWMDPRIWSRLPQPLLDRILAFLPLPAFFRARSVCKRWYALLYSNSFLQLYLQVSPTH
NWFIFFTHKTPNTSIIYRNNTTTNNNDNEGECCNGVSSSTSTRAYVFDPYELKWYTISFP
LIPLGFSPTTSSGGLVCWASDQPGLKNLFLHNPLVGSVAQLPPTRKPRLFPSVGLSVTKS
SIDLILAGDDMISPYAVKNLTSEMFHIDSDGFYTLWDPTSALPRLCSLESGRMVSSLGPR
YYCMNYSPYSVLAYEVASNMWWKIQAPMRRFLRSPCLVEINNGHKKVVLVAAVEKSKLNV
PRSLRMWVLQECGTQWVEIERMPQQLYAQFEEVEGGRGFDCVGSGEFVAIIIKGVNDSTN
NKGLLFDLNNKRWVWMPCCPRNHEISSNYVEGDLHGYGYQPTLVAPVTSLVQQLGALHHQ
SFTG
>Sgl23250 E3_activity/RING/RING 14.5 0.2
MASTSTARAIAGAATRIKDATSSLSSDNQPLISDIRKALNSMKEIAVEMEKLNRSQEVRE
LEDAFMQLLETFDESMNFSNVMQSVGNTYQPGPELTDFKKLFQSEVSKLKGGSTSNRQTN
ALLRQFKEAVWNVHHAGQPMPGEEQEDIVMTSTQIGVSNTVCPITGKSITELAEPVRSMD
CKHIYDKEAILHVIKNSTKRCPVAGCPKSLHATRVVCDPLLLVEIEELRSQNTNTVQLES
IIEDCTALEDED
>Sgl23271 E3_activity/RING/RING 30.8 4.1
MNERDMMCSTQRVLDLTSGQQVQSHLHPEPCIIMGSTSNIPRSHVNQVLPPSGSVNNFDF
HRLPEHVGRPAFYAMPQYNQHNHPATNHSNFMNLHLDPASGARVFPVPISHGFADHLPSS
SNYGANAVPFNEHVRSNYPAEGVRDLCKRKNTDGIPGNIQHLGASAGPSSSSGAAMANCH
FDSGSAYMDALPMTDYRGNGAPPMMEVGARNRSGGVGLHMDSGVHNYNNYLLQANYGGQS
FQPSSCTWVDQQSISNAGSLPWSGPHPMMSYFQGSNVHGGSSELANSSRSGYLERSSNHG
SANFLPTPPVVPQHHSLHPSQNIQGMGGYGVACYPPFLAAPTRVPPSDGMQHDVLSLSQE
SAEQANRPTGLRIYRSQGRNVVPDLASRRRDLPRLRTLQADSVALLEFSNYYEVDYNVEN
FIDHHSDMRLDIDDMSYEELLALSERIGTVNTGLTEKDIICHLKTKLYNSTGATFNLEEL
PSIDQDSDSCIICQDEYEDNDKLGTLDCGHDYHVDCLKKWLLLKNVCPICKSRALAVNQG
NK
>Sgl23278 UBD/UBC-like/UBD_UBC 169.3 0.0
MANSNLPRRIIKETQRLLSEPAPGISASPSEDNMRYFNVMILGPSQSPYEGGVFKLELFL
PEEYPMAAPKVRFLTKIYHPNIDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPD
DPLSENIAKHWKTDEAEAVETAKEWTRLYASGA
>Sgl23322 E3_adaptor/Cullin_RING/SCF/F-box 13 1.1
MSLSRSFLSRNRSSIRCFSLSSKSHKDHHHQTSSSSSSFSLPTSDFLHHHSSDATVNRNN
EFVVEDDDDGGRWSSLLPELLTDIISRVESSEDKWPLRRNVVVCACVCKRWRDITRQIVK
SPLATAKITFPSCLKQPGPRDVPLQCLIKRDKKNSTFFLYLSVSPSSFADKGKFLLAARR
YRRGAHSEYIISLDADDLSQGSQAYIGKLSSDFLGTNFMIYDSQPPHNGAKPSSSRSTRR
FASKQISPQVPAGNFEVGQVSYKFNLLKSRGPRRMICSLKCPPSPGEANLDQPEEAKIKL
SELDSIYTVLRNKAPRWHEHLQCWCLNFHGRVTVASVKNFQLIATVDQSQPGGKGDEEVV
LLQFGKVGDDTFTMDYRQPLSAFQAFAICLTSFGTKLACE
>Sgl23371 ULD/UBL/ATG8 165.4 0.3
MSKSSFKVQHPLERRQAEAARIREKYPDRIPVIVEKAEKSDIPDIDKKKYLVPADLTVGQ
FVYVVRKRIKLSAEKAIFIFVKNILPPTAAMMSAIYEEHKDEDGFLYMTYSGENTFGAL
>Sgl23374 ULD/UDP/UBQ/UBQ_PIM 105.2 6.5
MDVIFVAPKESFTIEIGYFDTVLEIKEKIQKYRKIPISQQILIFNGKILEDNGNVDSCVI
LHKSIIHLRISTPKSQSVEIHKQPQENLRLKNHSSNYHNNKNNKKIKYNNFNDFNFIHHS
SNNNNPDVISSKKVEILIHLPTSQNGINTDLVIDVDLNDSVEQLKRRIHHSEGYPAHLQA
LYINKRNVELQDNRKLYECELKNGSEIDMLIRLPQIPAPAPPSMMNEVSTVNSKKLKVIV
VTKCGTMKLPVEVNPFDKVQVLRKKLEKLQQKVKFELPEEGYFFIYKQRVMEEKETFRGY
RVRQDDTIDIFNGSVTGGQ
>Sgl23397 E3_adaptor/Cullin_RING/SCF/F-box 14.3 0.0
MWADLPRDILFYIVRYVDMKVDLPRVRGVCRSWRTALNLDELPRRDPHTIEVPNLEGIEI
ECYLRINSSPLFLLESRFYFISPVISSESAGTSNCNRGGWIARMCEAKTETGTGINNRWH
LLNPLRNNGTYYHENIKYLYVEPPITGTINMLDFRVLELARSYSLVNDKDNYNATDLSKK
VVGGWDYTSSYRFAALVQPDFKGHLLLLWRLGDQQWLKVVGKDVLRILDIAFLKGKFYVL
EQLFDQQRRVRVLNPQNPLVLLESTISVPDILLPSPKHMSGVDNGVSPFRNTFNLLPSKS
KGCLYLVLEDFLNEGNTEGGRPRFGSKIMFLVLMMENERKWKEMENIGDEIFFIGLDVAF
ALPSSSQNLPHWKQNSICFAVDQEYYSLDVYTRRTEVPGAECLDYVIYQTYNNCWSLFSL
EEKEKGDVPFDEMPKEEQELYLGLFFPPPAWVKWRCPTLDNVEVRLDGLRFPFQKRKKDG
LSFHEEEQQQEENSDD
>Sgl23398 E3_adaptor/Cullin_RING/SCF/F-box 14.5 0.0
MWADLPRDILFDIVRYIDMKVDLPRVRGVCRSWRTALNLDELPRRDPHTIEVPNFEGIKI
KGFHLTHSGPLFLLESRFYFISPVISSESAGTSNCNRGGWIARMCEAKTESGTGTGINNR
WHLLNPLRNNHAYYHGNIDYLYVEPPITGTINMLDFRVLELARSYSLVNDKDNFNAIDLS
KKVVGGWDYTSCYRFAVLVQLKIDGHVCKNLLLWRLGDQKWLKVVGKKVVWIFDIAFLNG
KFYIFEQLFDQRRVRVLNPRNPLVLESTISAPDILLPGPKLLSGVHGVVSAFWRVFNLLP
SKSKGCLYLLLEGFLDDGKMEGGRRRFGTNIMCVVLMKENERKWKEMENLCDEIFFIGHD
VAFALPSSSQNLPQWKQNSVCTFFDVDTFYYFDGYSHKTEMPEGAEYLDSVMYQSYNRYL
SLFNLEEKEKGNVPFDQMPKEEQELYLGLLFPPPSWVKWHCPTLDVEVRLDGLRFHEEEE
VEEGEGEEDSDEEGEEEGGGEEEEEEEEEDSDD
>Sgl23444 ULD/UBL/SUMO 108.6 0.1
MSGTTHEEDKKPGDQSAHINLKVKGQDGNEVFFRIKRSTQLKKLMNAYCDRQSVELNSIA
FLFDGRRLRAEQTPEELEMEDGDEIDAMLHQTGGAMI
>Sgl23445 E3_adaptor/Cullin_RING/DCX/DWD 136.2 27.4
MEIYNTKSIIHHINSRELHGFKGRKRPLFSYGTSIDEQNDEPSCSRGVSSSHFNGSTPPL
AVSFAKYCSVNLILEDIRNAHILGVTDEEGYVSLINTRSKLDPSATYEENAAKAIVSSWV
AHDNSVYDICWIKEDTNVLTASADHSIKLWDVEHKKCHGILRGHVGSVKSISCHPTNSDL
VVSGSRDGSFMLWDLRCSPQRGRDWIMQTDQVNGAHTSVKRKRFTRKKAASMTVTPFFNT
KSQTLSSNPPSRRKRPLFSYGISIDEQNDEPSCSRGVSSSHFNGPTPPLAVSFAKTIRNA
HILGVTDEEGYVSLINTRSKLDPSATYEENAAKAIVSSWVAHDNSVYDICWIKEDTNVLT
ASADHSIKLWDVEHKKCHGILRGHVGSVKSISCHPTNSDLVVSGSRDGSFMLWDLRCSPQ
RGRDWIMQTDQVNGAHTSVKRKRFTRKKAASMTVTSVLYLKDDVSIVTAGAVDSVVKLWD
TRNLRAPAAQASPLQETTSEMNGRLHGITSLSQDSNGVLLSASCTDNRIYLYNVLQLEKG
PISSFSGSQIGSFFIKSTISPDASHILSGSADGNAYIWQVDRPHHDPISLTRHEKEVTAV
IGKIATASDDYTVRFWDVQNRNYLLPRATTTRQKRVVKAPRTEYIEEKELSPQRDSPCNL
SDKEAVLQDQDQDQILVQLMKTPETEQDRFRRNLLLQGVSLKDAFNATYESPVWSPSSVL
SPPSSIKKRTIRDYFVVY
>Sgl23471 E3_activity/RING/RING 9.9 7.4
MEVDVGDSPKRKAEIVVPKVDCGGGGEGEGMEVGDGDGDGDGDGEVVKRRKKEVKNGKGD
NIDVDEDEMMMKRVAEIVLVLSAMGRMRAGRDPTVAEKAMMAEARLKVVALCEELTPKDV
VPLDAFGAIMEDLGLNRLKESLGVRHSKISISDKIANSKRRMEEAKAFAAQPVSSTSQRV
QTANGAAVDNRGTPPTVNVLPSDKAGHVPVSTGGFQPPTPVANVSSAASTPMQLHPPGFD
VRPAGHSPVLLNNIGRNSSSVPPPRNDRAHIKPEGRPNGQSMSHIPASSAASQHMSRTTP
VHARPQLPMQANVGTKSLVPDQMPVRAEGNLSLSAPQMTSQPAVAQMSGRAIGQTASGAL
PNVHHPVQGLPFVHGPVVNHHLEVSRLVQKLLTPKHPSRTVWTPPSRDYMNRALQCLYCK
FIINEVENMVVCDACEKGFHLGCLQSHNAKSIRGEWHCPRCLTASNGKQFPPKYGRVTRN
MNVPKVLSNTAGVQLQSDRKVITMSGKVNQPNATINRIQDVKRHSQANQPTNGTQDFKTH
SQAGKVIGSSTESILPRGSDNNAGNNLSVGEKEDRLKSEKCPNSTTGCVVETSSLTSIKP
SNDKTSQQVKTEILSEDLSETEPKPETTSQTNNKFNNLVTSSNDNNSEQKVVVSAEISVR
QQSDSNGIIESRQCKNDEKDVQKNLAEIKRDLDQAEELADASESPSGLHDVEWIGDADSI
MDKKKFYGSCRINGMVYQVQEYALLRSRSGKLIPMKLQAMWEDSQTNSKWLLVHKCYFPD
DLPGEVGRPGAPQSNEVYESTRDSYVLAGYVQGPCEVLPFKKFGEETEKSEQGSLAKDEK
QPIFIRNWFYDDTRQAFCPGAS
>Sgl23492 E3_activity/RING/PHD 34.4 26.3
MATSDDEMEDLPESVTNYYFVDDAEEPISFSVLHINWNTSEAVQGSGKQIYVRGNADAGL
DKIFKPVRAWKFDISGVKPEISVLSKDNNWIKLQKPRQSFEEYIRTVLITVNFLHLVKRN
PDFPGNRIWKKLSEIFGLYDVIPSSKDLRSHRVLIEQAVKQDESLKKSKYLLTVLERNQQ
KRHQAEEDDLVKGKGEFVVNDDELSDEFEEDSGDGVDGSGGEDGSADEEDDDEEPFDSVC
SICDEGGPLLCCDGNCLRSFHATVKAGKPSQCSSLGFTEAEVKAMPYFKCQNCQYKLHQC
YACGQLGSSDKQTGAKVFQCVNATCGFFYHPHCVAKRLIRNNEDSCKALAEKIQAGESFT
CPLHTCIVCKQAEDKTDPDLQMAVCRRCPKAYHKKCLPKEISFGEDEDEDEDMVQRAWEG
LLVDRILIYCLKHEIDDDLGTPARNHIKFPRDVKEKESSARVLKESKIAPKNKPSSLKRS
QAPLVLESKKKNIEDSDPDKKNDRRVPKLQTKVPLEKKSGLTKIGGTSGAEERKCLQQLD
VTKPSQIEKHDESESAGTNKAAVKKFVPQLDSDSERRILDLMKEASSIITLDDIIGKHEK
LIPSRAYKQKMDPCKNITEGKVQNLCVAISDVLKKIDRGSSFEEAKGACGPSDLNQLVKW
KSKLRVYLAPFLYGMRYTSFGRHFTKIDRLKEIADTLHWYVNDDDTIVDFCCGSNDFSLL
MKENLESRGKKCNYKNYDLFPPKNDFCFETRDWMTVQPSELPTGSKLIMGLNPPFGVRAC
KANQFIDKALQFKPKLIILIVPPETERLDKKKKSPYDLVWEYKDKLSGKSFYLPGSVDTN
DKQMEDWNVVTPVLYLWSRPDWTTKHMEIAKKHNHLLDEQRQKHNTSRLSRDLSFKDHGR
SSIAMKTDDASPQTQLPEGPEEKAVGGNEILEKQSAHKDHSIGKQANAAPAKGKKKKNSK
KKRRNEGIHKEDFKRRRFSPGNPQTEVSYRSPHNSRDGRETGNLRHHVGSPNFEPSPYAE
RRFSVENRPPRYHKSPSNGDLIHDQHLPGATGYGTANYDSPYYNDGTVNIHPSEQKIWPM
DQGPVADYGPHRNPVDSRMGYMRPDLHNYGFNHSYSTVEQPYETEAYAIETSGYDRRVNH
NPMSAMDKYKLRLDGPSSVRPGVGGYIPDVPHPPGVVFYDHHQAQAQRQVYPGGPMRFAP
GPPNHYYHHHHHTSSGGWIDD
>Sgl23563 E3_adaptor/Cullin_RING/DCX/DWD 97.6 8.2
MASSSSLNMCSNGAIGACNVSQSQTAFTSFCPDLFGKKLVNCMPIRSSADFAPLRNLFGA
KPLKWDSNGELSNKFGVPCHVVGVRNTNSFNVGQKFELNDVLEAQQFDRETLSAIFEVAR
EMEKVEKNSPGSQILKGYLMATLFYEPSTRTRLSFESAMKRLGGEVLTTENAREFSSAAK
GETLEDSIRTVEGYSDIIVMRHFESGAAKRAAAIAEIPIINAGDGPGQHPTQTIRNAHIL
GVTDEEGYVSLINTRSKLDPSATYEKMQEDTNVLTASADHSIKLWDVEHKKCHGILRGHV
GSVKSISCHPTNSDLVVSGSRDGSFMLWDLRCSPQRGRDWIMQTDQVNGAHTSVKRKRFT
RKKAASMTVTSVLYLKDDVSIVTAGAVDSVVKLWDTRNLRAPAAQASPLQETTSEMNGRL
HGITSLSQDSNGVLLSASCTDNRIYLYNVLQLEKGPISSFSGSQIGSFFIKSTISPDASH
ILSGSADGNAYIWQVDRPHQDPISLTRHEKEVTAVDWCLHEPGKIATASDDYTVRFWDVQ
NRNYLLPRATTTRQKRVVKAPRTEYIEEKELSPQRTALVI
>Sgl23580 E3_activity/HECT 406.4 0.0
MESEEGSIPIILLLKLLNRPLFQRSIAHVEQVMSLLQVVVYTAVSRLESPSLPEQVTDDP
QALSVKASDEIQRDVTLLETETSNQVKKVETEKPSISERKEGHKIFDVFTQLPRSDLRNL
SRILGCEGLSDKVYMLSGEVVKKLASVTASHREFFIQELSVLAQDLSSDAVEELATLHNT
KMMGLGVGAMAGATILRVLQALSSLVSQGVDNAVCQGSNDEEEQAILLKLNSALEPLWLE
LSYCISTTESELGQSTLSPTMASINAGDGAAGSSISSPPLPPGTQRLLPFIESFFVLCEK
LQSSNSFLQQEQTNVTAQEVKESADSSSSVPTKCGGDSQRRSDSAFLFSKFADKHRRLLN
AFIRQNPGLLEKSLSMMLKAPRLIDFDNKRAYFRSRIRQQHEQHLAGPLRISVRRAYVLE
DSYNQLRMRSNQDLKGRLNVQFQGEEGIDAGGLTREWYQLLSRVIFDKGALLFTTVGNNA
TFQPNPNSVYQTEHLSYFKFVGRVVAKALFDGQLLDVYFTRSFYKHILGVKVTYHDIEAV
DPDYYKNLKWLLENDVNDILGLTFSMDADEEKLILYEKTQVTDYELKPGGRNIRVTEETK
HEYVDLVADHILTNAIRPQINSFLEGFNELVPRELISIFNDKELELLISGLPEIDLDDLK
ANTEYTGYTVASNVIQWFWEVASNFSKEDMARFLQFVTGTSKVPLEGFKALQGISGPQRF
QIHKAYGAPERLPSAHTCFNQLDLPEYSTKEQLCERLLLAIHEASEGFGFG
>Sgl23581 UBD/Alpha-Helix/UIM 14.3 0.7
MYVFNVITLDFFTSLLLQPPKIRSFINSVTSTPLENIQEPLKCFVWDFDKGDFYHWVDLF
NHFDSYFEKHIKPRKDLRFEDDFLERDPPFPKEDVLQILRVMRIVLENCTNKHFLSCYEH
LSSLLASSDADVVEVSLQTLATFLKKTIGKYSIRDASLSSRLLAFAQGWGCKEEGLGLTA
CALNSGCDSVPYELGSTLHFEFYRVAESSSEYEATGGLQIIHLPHVNSRKESDLELLNTL
VKEYGVPLNLRYSLFTRLRFARSFGSLTSREQYTCIRLYAFVVVVQANTDADDLVSFFNT
EPEFTNELVSLLSFEYSVSEKIRILSLRSLVALSQDRSRQPTVLAAVTSGGQRGILSSLM
QKAIDSVSNGSSKWSVLFAEALLSLVTVLVSSSSGCSAMREAGFIPTLLPLLKDTDPQHL
HLVGTAVHVLEAFMDYSNPAAALFRDLGGLDDTINRLKVEVSVIENGLQQPSGSSDGSMS
TDGTVGNLGTSSVLDDILPLYSESLLAYHRRLLMKALLRAISLGTYAPGSTDRIYGSEES
LLPQCLCIIFQRAKDFGGGVFSLAATVMSDLIHKDPTCFSVLDAAGLPTAFIDAIMDGVL
CSADAITCIPQCLDALCLNNTGLQAVKDRNALSCFVKIFTSKGYLRALAGDTPGSLSSGL
DELMRHATSLRGLGVDMLIEILNTISKLGSADEASASPVESLTCPAPVPMETDLDAKNLS
SVESELPKSEITDPTDLPSDPTLVESYLPDCISNACRLLETILQNSDACRLFIEKRGIET
ILQMFSLPLLPVSVSVGQSVSSAFKNFSAQHSASLARAVCSFLKEHLDTTIEVLDSIEGT
PVANLESAKQIKVMRCLSTLEGILSLSNSLLKGTTTVISELGTGDADVLKDIGKIYREIL
WQISLSCDSKVEPKQNAEVETENVDAASSSAIGRESDDDTGIPMVRYMNPVSIRSSSQSQ
WAGERDFLTVIRSGEGLSRRNRHGLTRIRGGRTGRHLDSFNIDSEVSANVHEPSAALLEH
KKKSPDVLASDILFKLSGTMRSFYTALVKGFSSPNRRRADSGSMSSVAKNIGTALAKIFL
EALNFSGYSSPAGLEMSLSVKCRYLGKVVHDMAALTFDSRRRICYTAMVNNFYVSGAFKE
LLTTFEATSQLLWSLPCPFPTFGVDSGKAGEGSKLEHSSWLLETLQSYCRLVEYFVNSSL
LLSPTSPSQAQLLVQPVAVGLSIGLFPVPRDPEVFVRMLQSQVLDVILPVWNHPMFPQCS
ASFITSILSLVTHIYSGVGDMKRNRSGVTGSSNQRIAPPPDEATIATIVEMGFSRERAEE
ALRRVESNSVEMAMDWLCTHAEDPVQEDDELARALALSLGSSTETSKADNSEKSADVIGE
EGQMKAPPVDDILGASMKLFHSGDSLAFPLTDLLATLCNRNKGEDRLKVASYLIQQLKLC
SSDMSKDGSAVSSISHILALLLSEDTDAREIAAQNGIVSVAIDILKNLIGNQLGSDILIT
KSTSALLLILDNLLQSRPRISADKAGVASTEPLSDLSVEVAPVEASGPDMEKKLTSDVCE
EKWVSSFQKIFGKSTGYLSMDECHAVLQIACDMLKQQVPAVIMQAVLQLCARLTKTHVLA
LEYLASGGMAALFDLPRSCFFPGYDTLASAIIRHLLEDPQTLQTAMELEIRQTLSGGRHA
GRIPTRMFLTSMAPVISRDPVIFTKAAAAVCQVESSAGRTVVVLSKEKEKEKDRSKVSGA
EVGLSSEAVRIPEMKSQDGPGKGSKGHRKIPANLYQVIDPLLDIILQYPCTNSQEDHFSC
QAVMDVDEPSTNVKGKSKIDEANKGDADILPERSAALAKVIFVLKLLSDILLMYAHAIGV
VLRRDSETCQLRGSSQPDASGQGGVVYHVLNKLLPLSSDKSSGLGDLRTKLSEKASWFLV
VLCGRSSEGRRRVISELVKALSLYSNMGSNSHQSSLLPDRKVLAVVDLVYSVLSKNTSST
SLSMPCYSPDMARGMIDGGIVPCLSNILQVIDLDHPDAPKIANLILKALESLTRAANASE
QSYRSDVQNKKKSNCSQERPDDQTINASTNDTIHNDVSQISEQETRNVGVVEPNPCEGAG
RESNHVTDMDGSANLDGRPEGEGVPDANPAVELGMDFTGDDLEEGDIMHNNNRISMEFHV
ENRADEDVGDDDDDMGGDGEEEDEDEDGEDEDEDIAEDGTALMSLADTDVDDHEDAGFGD
EFNDEMIDDEDDDYHENRVVEVRWREALDGFHHLQVGPGSGLIDVPSEPFEGVNVDDLFG
LRRTLGIERRRQTTRSFERNSTDGGLQHPLLLRPPQSGEAPLLSSGGNVARDSESLSGAG
ADVSHFYMFDTPPFLYDFGPGSLFGDRSGGTAPPPLTDYSVGMDSSQLGGRRGPGDGRWA
DDGQPQAANQAPAIAQAVEEVFVSVLRGANVTDTAVGRQSPSMGLPEQQLDAGQNSDHLG
LEEDLSHGQSEEVQLGNGEPEPQQTNSQNTVSAQDHVITHTVTEVSAALERELLASNPVH
DSIESANGNDPPSDLMRTERDPSLSSVGLEHNILHEGDLGQLHNQQDAQRLARLADVSSG
SDFQPNNDVNNPGVALFNQVEHHPSSCASPDIEMNGADAEPVQTNELQAASESNEPVSDQ
NISINGSSMDADQVGANVEPSRSNAIDPTFLEALPEELRAEVLASQQSQSVQPPTYTPPS
VEDIDPEFLAALPPDIQAEVLAQQRVQRMAQQSEGQPVDMDNASIIATLPADLREEVLLT
SSEAVLSALPSPLLAEAQMLRDRAMSHYQARSLFGSSHRLTHRRNGLGFDRQSVMDRGVG
VSIGRRTGPSLSNAFKVKEVEGEPLLDGNALKALIRLLRLAQPLGKGLLQRLLLNLCAHS
LTRATLVHHLLEMIKPEAEGIAGSLSMVNPQRLYGCPTNVVYGQSQLLDGLPPLVLRRVL
EILNYLATNHSAVAKYCSTVSHHLYLNPRRSLQKRKRAKKK
>Sgl23594 E3_activity/RING/RING 23.5 13.9
MGFLNHVQISSSRFVHGETRAVEEEEELGEDAPRILTSDQIRPTREIPASILVRTAMRVS
RSKWFTFLRRVFHYQNGSRSHLGANPFNSCSWMMLELLALLVQICVTMITLFVSKAEKPV
WPMKIWVVGYDFGCVTSLFILYWRYRHYHLRQQRDNNGISFPDLEQQSSINEESSRELHL
VNKCKASLDLFFAMWFVMGNVWTFDSRFGSFSRAPKLNSLCITILAWNALTYSFPFILFL
LLCICVPLLSSFIGYDMSLGSAEKGASDDQISSLHCWKYKLVEGNTIDPGNSSPAKDNPE
CCICLTKYKDKEEIRQMPCSHIFHKICVDQWLKIISCCPLCKQGLHV
>Sgl23630 E3_adaptor/Cullin_RING/BCR/BTB 56.1 0.0
MKSSAYHVHTTSRLAQWRIHNLSSCTFRRSDPFPLGLWNWHLALEKNKVLMLKLYPEISN
FTRDNPPIASFVILVRVLFSDSDSDSDATTHPNRNPLVIVHPEISDQLLKTNNDFVWPID
VPVPLTGKLIIDLEFFDLKTSSPQGGEPCSIWAAEGSTSIRRSNGAALTSLRRMLMDGIY
TDITINTSNGRVGAHRAVLAARSPVFQTMFSHNLQEKELSTINISDMTIESCQALLDYLY
GCVQHNDFLHHRLSLLRAADKYDITDLKEACHVSLLEDIDANNVLERLQNAALYQLPELK
SSCMRYLVLFGKIFDLREDFNVFLQCADRELIADIFQEILATWKGF
>Sgl23631 ULD/UDP/UBQ/UBQ_PIM 65.5 0.9
MKITVMTGDEQIISLDVDRDEAVENVKALLEVESGVTLQQQQLLYNGKEMNNHEKLSALG
VCDGDLIMLMHSSDGSSNNANNLALNPDGSAVNPAAFQNQLLSDSTLMAQLFQSDPELAQ
TLSGNDLNSLQEILRQRHRQRAQMKQKENEELALHYADPFDVEAQRKIEASIRQKGIDEN
WAAALEHNPEAFARVVMLYVDMEVNGVPIKAFVDSGAQSTIISKSCAERCGLLRLLDERY
KGIAHGVGQTEILGRIHVAPIKIGNMFYPSSFTVLDSDNMEFLFGLDMLRKHQCIIDLKD
NVLRVGGGEISVPFLPEKDIPPRFLDEERFSKQASGSGAQVSSGSKGTRDATTGSHSSGG
AGGNPGQGSDFEAKVAKLVELGFQRNDVIQALKLFNGDEEQAAGFLFGG
>Sgl23632 E3_adaptor/Cullin_RING/DCX/DWD 42.1 0.0
MASTGNPNQNQQQQQQQQQQQQQQGVGVGVGGQFDMNKFFKPTNITSPTHTQAQNPNNIN
MNMNIGATAAAASYPPPTTGSAPYSYPPQNPGPPYYHHMPPFPPPQDHMHHQRSVSFPTP
PLQPAPQNSNPGARLMAMLSTPPPDFNYSHQNPTPVPVPVPLPSAPLPSSSSDFSTVPSL
HPQPTPIRMPSSKLPRGRHLLRDHMQYDIDVRFQGEEQPQLEVTPITKYVSDPALILGHQ
IAVNKTYICYGLKMGNIRVLNINTALRSLLRGHTQRVTDMAFFAEDVHLLASASIEGRVY
VWKISEGPDEEEKPQISGNVVLAIHFTGDEGSVHPRVCWHCHKQEILVVAIGKSVLKIDT
TKVRKGVEFSAEEPLVCPLDKLIDGVQLVGKHDGEVTDLSMCQWMTTRLVSASKDGTIMI
WEDRKALPLLVLRPHDGLPVDAAKFLAAPHRPDHIMLITAGPLNREMKLWASSDEEGWLL
PSDAESWRCIQTLELKSSAEPRNEEAFFNQVVALSQGGLLLLANAKKNAIYAIHLEYGAN
PAATRMDYLAEFTVTMPILSFTGTSDVLPHGENLVQVYCVQTQAIQQYALDLSQCLPPPL
ENLGIEKSEATITRDAAECVPPLEPSGSKSFEAPFSAAKPSNSSGLASSSDIKSPVSTAS
DTILVQESSTSNVDPNPTSLLSASSNANLAPVTSPSLPLSPRLSKKLSDLRGDQAVTDYP
IDRQIDTAQTSSSALAASNDDNLTVQGTSDIVNPPVMFKHPTHLVTPFEIMATSSADATR
VSEKGENEAKVQDVAVSNETENVEVEVKVVGEAGLANSDECTRSVDPQIMTDRKEKSFFS
QASDLGADMSRECCALPSETSITEEARNSIMEALAQPSNSGEEEGDEANNDVSVKGADFA
APVAVPQSPTPGAKGKRQKGKNSQASGSLSPSPSVSNSAEMLQGTVGGSTVPFMEPSTSQ
MLAMHETLNQILTMQKEMQKQMSTVVSTPVTKEGRRLESAIGRSMEKASKANTDALWARI
QEEITKLDKSVRDRMQQIPGLISNIVNKDLAAVFEKTLKKELTAVGTSVARTISPAIEKT
ISSSIADSFQRGVGDKAVNQLEKSVTSKLEATVARQIQAQFQTSGKQALQDGLRSCLEAS
IIPAFEMSCKAMFEQVDSAFQKGMAEHTTAAQHQMESSNSQLAHTLRDALNSASSLTQTL
SGELADNQRKLIALAAAGTNSKAGNSLVPQLSNGPLASLHEKVEQPFDLTKELSRLVSEH
KYEEAFTAALQRSDVFIVSWLCSQVDLQRLLSTIPLPLSQGVLLSLLQQLSCDITKDTSR
KLAWMTDVAACIIPHDPVIAVHVRPILEQVYQILNHQRNLPTTSAAELSSIRVVMHVINS
MLLTCK
>Sgl23718 E3_adaptor/Cullin_RING/DCX/DWD 70.4 13.4
MAKIAVGCEPVVGCLTAPKKKDYKVTNRLQEGKRPIYAVVFNFIDSRFYNVFATVGGNRV
TVYRCLEGGTIAVLQSYIDEDKEESFYTVSWACDIESNPLLVAGGSNGVIRVIDASNEKI
HKDESVRLWNVHTGICILIFSGAGGHRNEVLSVDFHPSDIYRIASCGMDNTIKIWSMKEF
WTYVEKSFTWTDLPSKFPTKFVQFPIFIASVHTNYVDCTRWLGDFVLSKSVDSEIVLWEP
IIKEHSPGEGSVDILQKYPVPDCDIWFIKFSCDFHYKAAAAGNREGRIYVWELQSCPPVL
ITKLSHPYSKSPIRQTAMSFDGSTILACCEDGTIWRWDVVS
>Sgl23730 ULD/UDP/UBQ/UBQ_PIM 634 30.6
MQIFVKTLTGKTITLEVESSDTIDNVKTKIQDKEGIPPDQQRLIFAGKQLEDGRTLADYN
IQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVESSDTIDNVKAKIQDKEGIPPDQQRLI
FAGKQLEDGRTLADYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVESSDTIDNVKA
KIQDKEGIPPDQQRLIFAGKQLEDGRTLADYNIQKESTLHLVLRLRGGMQIFVKTLTGKT
ITLEVESSDTIDNVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLADYNIQKESTLHLVLR
LRGGMQIFVKTLTGKTITLEVESSDTIDNVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTL
ADYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVESSDTIDNVKAKIQDKEGIPPDQ
QRLIFAGKQLEDGRTLADYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVESSDTID
NVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLADYNIQKESTLHLVLRLRGGL
>Sgl23799 UBD/UBC-like/UBD_UBC 154.2 0.0
MNSGGGGGGVGGTGTGSSGGGRMSASRSSWRSTSVSGSGKRIQKELKDLDSHPPPLSSAG
PIADNLYHWLATFIGPPGTPYEGGIFFLHILFPVDYPFKPPKVVFKTRIYHCNVDSSGNL
NLDILKDAWSPALTISKLLLAIKSIFLTPLLNPYYVVPSIAHLYHVDRKTHDQLAAQWTH
LGLPLCSVNVNVNVNVNGGIMHSSNTMSKTKQPPPATGHRPPPPQVEQWRRFYSRISSIS
SQLILMARSSTKSDKFDAYILLDVNIDVYRFNKDNRYTIGFATTFDLDGTPDTGYYNQTS
RETLADRYEYVMHGRTYRIADVDHEGQEKGEIYVSFGGLLMMLKVDKSVSKNFELDQRLF
LLMKRIE
>Sgl23876 E3_activity/RING/RING 28.5 6.6
MSWNQHMDSHYHYVGSNAPYNSAGSFMDFFAGLTYDHVNFIFSGSQIQDCSYSPISPGYY
KFGYPDPGATQYYSNSPAYEVYDHIVSGIDDYTRRPSDFPSSDQTAAANHQSQRMSNTSN
RDCPRSHHSSQDYQTIWQDNIDPDNMTYEELLELGETVGTHSRGLSPQQIALLPVTKYKC
CFLLRKTYRSERCVICQMEYKRRERLITLPCKHKYHLGCGTKWLSINKACPICYTEVFAD
ANKKSK
>Sgl23910 E3_adaptor/Cullin_RING/DCX/DWD 24.6 2.4
MDRYVVPTEPLSSNPNPIRRHRWKRTAIELDGCIESKYKRELSGLLVQSYAEIGVFSHLY
HIDGRPCSTHRNRVMSFAGLDHQGSFRRHGVSALEFDNQVACTSLKSSEIHIFDIGYVSS
DPVEVLRKKPSVTINGSNIVTGLSDVAFTSSDDSRVFASDTSGSINIWDRRQGVFPCLEL
TTNSQNALNSIQLNVENQIVFGAGKQGMIYMWDLRGGRTAAAFQSHKEAYHPPMTSVKVS
SLLEKIESLKAQSDVVPKDIHSINLDPSSLFRLAFHLDDGWSAILDIHSLEVTHIHCPPP
AWLTGSEMSNLSYLTKPTWLSTNSIYAVGSSSDKGLHLLDFYPDSSSPCHVEFSEDMVNT
SRRNRFVPLSEDVSACAAHPLNGFIVAGTKQGSLLMIGQRKKAVRGDDGF
>Sgl23929 E3_adaptor/Cullin_RING/SCF/F-box 12.6 0.2
MIFFLVTGISFFFFLNSLSLKPLPPWANDVRLLPLCFWKELSFSPICKGFKKGVFGDFWG
LPSIMAMKQGSSSSKFENSQESGQLSVLDLPELALDCILEKLPPSGLCSMAAVCSSLKER
CISDHLWKTHMEHKWGKVLGPAASREWQWFIACKRNSSASVGKKSQSFIKFIWNVWPLTW
FTSKYDKTNNINKDSTSPSPSPMVDSVMSWYLALESGKFWFPAQVYNRENGHVGFMLSCY
DAELSYDPQSDTFQARYPPHGRRAVAIESGIQWERLRAAPVDTPPHDLHPSDCLNDLHPG
DHIEIQWRRNKEFPYGWWYGVVGHLESCDGNENYCRCHSSDTVLLEFNQYTPGSRWRRTI
VSRKDHREEGNESDGFYGGIRKLHKRDEIATWKSLWPKEILD
>Sgl23988 UBD/Alpha-Helix/UBA 16.6 0.4
MDGQGVRGGSSVDSFLQNYNLGKTLGIGSFGKVKIAEHKLTGHKVAIKILNRRKIKNMEM
EEKVRREIKILRLFMHPHIIRLYEVIETPSDIYVVMEYVKSGELFDYIVEKGRLQEDEAR
MFFQQIISGVEYCHRNMVVHRDLKPENLLLDSHHNVKIADFGLSNIMRDGHFLKTSCGSP
NYAAPEVISGKLYAGPEVDVWSCGVILYALLCGTLPFDDENIPNLFKKIKGGIYTLPSHL
SPGARDLIPRMLVVDPMKRITIPEIRQHTWFQAHLPRYLAVPPPDTMQQAKKIDEEILQE
VVRMGFDRIQLIESLRNRLQNEGTVAYYLLFDNRFRASSGYLGAEFQETLDNKYSRMHPN
EPASPAAGHQYHGYVDYQGIGLRPQFPVERKWALGLQSRAHPREIMTEVLKALQELNVVW
KKIGHYNMKCRWLPGIPGHHEGMVNNPVHNYLGEESSIIENDGVLRSPNVVKFEVQLYKT
REEKYLLDLQRVQGPQMLFLDLCAAFLAQLRVL
>Sgl23991 E3_adaptor/Cullin_RING/DCX/DWD 102.2 11.5
MSTLEIEARDVIKIVLQFCKENSLNQTFQTLQNECQVSLNTVDSHETFIADINSGRWDAV
LPQVSQLKVSRKKLEDLYEQIVLEMIELRELDTARAILRQTQVMGVMKQEQPERYLRLEH
LLVRTYFDPHEAYQDSTKEKRRAQIAQALSTEVSVVPPSRLMALIGQALKWQQHQGLLPP
GTQFDLFRGTAAMKQDVEDMYPTTLMHTIKFGKKSHPECARFSPDGQFLVSCSVDGFIEV
WDHISGKLKKDLQYQADETFMMHEEAVLCADFSRDSEMLASGSTDGKIKVWRVRTGQCLR
RLERAHSMGVTSLCFSRDGSQILSTSFDSTARVHGLKSGKLLKEFRGHNSYANHAMFTHD
GSRVITASSDCTVKVWDVKTTECLQTFKPPPPLRGGDASVNSVHLFPKNMDHIVVCNKTS
SIYIMTLQGQVVKSFSSGKREGGDFAAASVSPKGEWIYCVGEDRNLYCFSVQSGKLEHLM
KVHDKDVIGVTHHPHINLVATYGEDCSMKLWKP
>Sgl24028 E3_activity/RING/PHD 35.7 18.1
MNARKLLLREEVEVRQLEEGLKGSWHSGVVVGVSDSCREVKYDELLCESGKSMLIESIPV
TGAIEGLYQRPCVKFNYRGRIRPIPPLAQPSAAETHLAFGVCVDVWYNEAWWEGVIFDCN
EDAKERRVFFPDELDERVYKLNDLRVTWEWDEFTGQWRERGVWMLVNLAKEHKKSGYLFH
FIRRVWSCLKVHYGFKKMISEWTCGAYCVWKEYFREVIYEMTTKPVGKGLAFPTQVHAAK
KRKRRSKRAQVRFLNASVLTRSMQKTVEKEIRLAVRTRRMCMSEAEDSLIAASKKNSHFT
DSYFQQSRSVTADACINTDIDVSRSDDNTEREQVPRQCCDQIGAKVVDDGCCHSRMPQND
SLPSMDSRMPENCIKTSNNRLRRKWQLAEANLPPKKLMASPLCENNLDINRSHGFRITRQ
MQGRVPLQFQDNDPVYKSRELLLLKQKKVGVAMRYPVHRKGKRIRICRRSIGKKRSPKRR
IKKILPRKTQEATIKASKPMLQRELKESESQQKVGDSFAGHCDEIQPVTTSLQEDETQDP
VETAPKQKGKRSRCRDSVCLVCQYGGELLHCDRCMSSYHLACLDVKEFPVGESFCPSCEC
GLCGLEHSSSDDQLFTQVCYQCSRRYHVACLNEVEAKVSEDSFSDKFCSRSCFKICARLH
ELLQISNPTTMEGLTWTITRSRRNDCNVHNERVHPLIQVSQVLNVFHECFEPIAEPHTGR
DLVADIVYNSGSKFRRLDFHGFYVIALVDGEEVVCVATIRIHGQKVAEMPLVATRFKYRR
KGMCRILVDELEKMLVEMGVERLVLPAIAQLSDTWVSSFGFADMPAPLRRELLGYPFVLF
QGTTMFQKILRRPAPPDSLLAGPELAQGKHTERDCNRRFSLQYKRRGKSEASGKKKTVMD
GSDRNQSSYKLVYKRRRIQASRDSIDIQ
>Sgl24032 E3_activity/RING/RING 16.7 10.0
MGNQNSTDEEREVPNPISIPIPIQSPSVAGTSMSYTQIQKGKQLPKYIADNFNSLDEVTE
ALRRAGLESSNLILGIDFTKSNEWSGKYSFNRRSLHAVGGDPNPYEKAISIIGRTLSPFD
EDNLIPCYGFGDATTHDRNVFSFYPDYRSCYGFEEVLARYKEIIPYIKLSGPTSFAPIIN
AAIDIVQSSNMQYHVLVIIADGQVTKAPDLQPGKLSPQEQSTIASIVDASYYPLSIVLVG
VGDGPWDAMQKFDDNIPQRAFDNFQFVNFTKIMSENKDISKKEAAFALAALMEVPIQYRA
TQQLVFNDKKIGGGPRCSPLPPPREVIDHDNSVKQASHSRSSSSVESTIPMDSNIPLEQA
CPICLEKPRNMAFGCGHLTCKDCGETLSTCPLCRKAITTRFGLNRVQSGHRIYCYEAFET
GYLAEKLVIIGE
>Sgl24045 E3_adaptor/Cullin_RING/SCF/SKP1 100.4 0.2
MASSSSTPKKITLKSSDGELYDVDEIVALESQTLKHIIEDDCGDTAIPLPNVTSKILGKV
IEYCKKHVNSRSISSDDVKDAEELKKWDNEFVKVDQETLFDIILAANYLDIKSLLDLTCQ
TVAEMMKGKSPEEIRKTFHIVNDYSPEEEAEVRRENAWAFE
>Sgl24060 E3_activity/RING/RING 29.1 16.2
MKVNILQWHAVASWTWDAQDETCGICRMAFDGCCPDCKLPGDDCPLIWGQCNHAFHLHCI
LKWVNSQTSQAHCPMCRREWHFKD
>Sgl24233 E3_adaptor/Cullin_RING/SCF/F-box 20.4 0.0
MKKVKAATGNKYFSLLPTELCSEILSWLPVTSVGRCKCVCKSWRDMINDPNFNKLHFGRR
SVETHYYSNTTRLIMFTPYRKPPLKRISSFNVNDYKLSNFTQLYYPTQLPTTLLYLIGCC
NGLICFSSYHKTCDHRFFLYNPITGAYKHVPSTSTSTLISKDLWINSFGYDHISDDFKIL
LISHTEIVKYTTLLYSLKLNAWEVIENPPSSWEVDEFSKSNTPILINNSFHWLGLTTSLS
SARVFKTIKGFEISSRRYFEMQLPKGVYTNLPKLTVLQGQLCVVTCCLDIWILKEYGDHK
SWTQILFGKVYDGLLNNFDVLQDWGRYKCISCFQNGPNNIILVITRMAPDFSTTQLEHYL
ICCNYESRTLEKIDISDCLKHDSCDSNLPIHAIQPWVDSLVDPDALSSLS
>Sgl24261 E3_activity/RBR 147.9 26.1
MDSEDDMHDANDVESVEDFYSGDTAIDSDDAADGDYEFIDNDSEEDYDDFTSHRNQQNYT
ILSEADIRQWQEDDILKISTVLSISKVEASILLRHYNWSVSKVNDEWFADEEKVRKTVGL
LDRPVVEFPNTREMTCGICFEAFPSAMMSAAMCGHPFCNSCWSGYLGTSINDGPGCLMLR
CPDPSCGAAVGQDMINKLACEEDKRKYARYFLRSYIEDNRKAKWCPAPGCDYAVDFVVGS
GNYDVNCRCSHGFCWNCTEEAHRPVDCGTVCKWIMKNSAESENMNWILANSKPCPKCKRP
IEKNQGCMHITCTPPCKFEFCWLCLGAWSEHGERTGGFYACNRYETAKQEGVYDECEKRR
EMAKNSLERYTHYYERWASNQSSRQKALQDLQQMQNVHLEKLSDIQCQPESQLKFIIEAW
LQIVECRRVLKWTYAYGYYLPEHEHARRQFFEYLQGEAEAGLERLHQCAEKELQVYLNAE
GPSKEFNEFRTKLAGLTSVTRNYFENLVRALENGLADVDTHGACSRTATSKSLGGSKSRN
GRGKGASAKSSSSTRNIDDSSHWSCEHCTFANVRSATICQMCHNRR
>Sgl24276 E3_adaptor/Cullin_RING/DCX/DWD 181.7 22.4
MSSSTLDPSHSFKPYTLKQTLTPHKRAISSVKFSSDGHLLATCSADKSAAVFSLSTTTSS
DDSPFSNLQHFTGHDQGISDTAFSSDSRLLATASDDKTIKLWDITTGQCIKTLLGHTNYV
FCLTFNPQSNMLVSGSYDETVRVWDVKSGKCLRVLPAHSDPITAVDVNREGSMIVSSSYD
GLCRVWDVSTGHCTKTLIDDENPPVSFVKFSPNGKFILVGTLDNTLRLWNFQTGKFLKTY
SGHVNSKYCVSAGFSITNGKYIVSGSEDNCVYMWELQSRKVVQKLEGHTDTVISVCCHPT
ENMIASGALGNDKSVKIWTQGKA
>Sgl24281 E3_adaptor/Cullin_RING/SCF/F-box 14.2 0.0
MSSSISTDYYLSLELWEDISARLPIKTLLRMRSVCKAWRSMIDSPSFTDMHYRIYNESNP
SKAKLLLCAAESQNLYRYGSCKFTTRHSTTFRKVDEVCEISNLSKEIILLGSCNGLWLIE
HDDGDDYRSVGRVAIRRVLNPFVRKSFRLPDDQIGLFTVNCVLGFAPSTNDYKVVRFMQD
IRTSDFSISVCSLSGEGDHKWRTKSDKISVPIWNLSKRLRATDVLFIKNAGYWLNENASL
LMWFDFDREELSFSALPDAAEDTQTLPSKFIFNFLDSIAVLSISYSSTRVWTFDKNSSSS
SGGGGNNKDHHPWRLWLSTDTHPNAVKFLANFQILPKAILYQHATSTFFMPVRCPASRKL
VSYNVSNHKVRYLSKQGFWSSVDNYVENLVSHNHPQWKRCDIFSPKKAKLVHSPLPYPYP
FPFLFPTELISRAFRRKRRVL
>Sgl24282 E3_adaptor/Cullin_RING/DCX/DWD 23.9 1.5
MEDHFEEEDNDLDLFPSTSSYPRTPKIFDRFGSSSSSDEDISPSSTSSAIHQNPNSTTNS
SNGVVKAAGKKLDYMIQFLDRKLSKVGSANSSSNGGSGAQNFPLPEFVGSGGGTGIFRLP
IRSAVRPDRPPCVEVRPRPRRETQVGRGLRTMASTDKQLWCGGENSVRCWELSDIFSCND
EDDDGNGGDCGCEVGNCVCMSEAKRSGDEMTARFKESIEVVSEVVCMVEDEGERVIWSGH
KDGSIRCWRMDDAKKNGFKECLSWQAHRGPVLSMVMTSYGEFNLCFNLRKYELIHFRKLM
MKALVM
>Sgl24306 E3_activity/RING/RING 34.5 18.3
MSSGGHTHWCYQCRQPIRLRNRGMVCPYCDGGFVQELEELSGGPVGGITPHGLRDGPDQL
YGIMEALDSLMLRSNPEHRLGLIEALDAFMGQRRRHGIDAERSPWLIFQGQVPGRVPMPR
NGGFEMFFNGNPGVGFSRGNNGDVFVGPGLQDLIEQLMVDRQGPPPAPRTAIDALPIIKI
TRAHIQADSHCPVCKDEFELGAEARQMPCNHVYHSDCIVPWLVQHNSCPVCRHELGSSTS
SCRQNPNSSSRRSATSSSSRERGSSEQNTSRRNPFSFLWPFRSNNSSSREYVPPSANNPP
PTRGENHEMNYSGWPFDY
>Sgl24309 UBD/Alpha-Helix/UBA 24.8 0.2
MSSVSKSKSKDKKAVKEQKTPSKSSAPPNGGSGLPASAYNPLLGTFHTIEPSSTAPTLHV
NGRFRNIDDSDDHSGSTHGSGGDYDSASNNDSRSVESEEHNKDKLNGPLKQEVVPGADND
KREKIRQKNERKHQRQKERRAQELHERCSGYLMSRKLEALAQQLVAMGFSHERATMALIF
NEGRVEEAVAWLFEGGEDADKHKEQNLDTGSNLKIDISDELARIAELESKYKCSKQDVER
AIVTCEGDLEKAEDNLRSLKQDQFAVLPKSDETGDPPTLSNGRVSIAPSLSNVRLLQSKP
NAATLIPQRRDEKDFNYTKAAVTGGLASKLVPKTVQPVQRVQPKLEWPRPQQINTPADKR
WPVGAGSSPSVSYSLAPPLQVSPPPSKAELRYATVGNDYKNLQPGSVREPVVMMQRPQSV
NVKPAPATSISSSPPGSVAGWYPTSSEILKPNGLLPHIPSTRSLSPNNLTSNQFYHPAQY
QQQQQQQQHQQQHQHHHQHQHQHQPYMPGSSPMDNPGNARGSTSWSRMGGSSTIAPASSL
GLFSGLGSNCSSGSNSPVDWNTSGSMPSCDYTNIDWSLDRSFLPSKQNGLWMGVAPYSRS
SGSHIYDSGASAMGIPIPMRPSSSSSGNGVPIVGLQEGGAGMADTSGSSSREWTSPFEGK
DLFSLPRQFVSSPSL
>Sgl24323 E3_adaptor/Cullin_RING/SCF/F-box 18.9 0.0
MAIGREKDNCNSRHFSLLMKSCCPNPTDPSHSVIPFPPNTNNHKTPKKVISSFSKTSISS
LPDDLLYEILTRVPLSSLPSISAVCRRWAHLLHSPSFSLLRRNHRLIHPTIFAFSPSSTS
TLRVFLDDAWKMPACENDVVFGGSLQFQLHTEFSHARVVGIGRKAYVVTREGTLVYDPWT
GVVKPRAGPLFSRKRFAAASICGRIYVAGGSLRASAIEEYDPHADEWRVVAHAPRRRYGC
IGVGVDGVFYIVGGLMIGGASESRAAEARVCASSMDLYDVAGRGWLRSRAVPGGGCVVAA
CGAEGCVYVLASHAVELSFWRFNGRRKGEGGGGVFGEWCRMRSPPLPAQIRLDGTVRFSC
VGVEDKVVLIQVMGSIDDLLRRSGRNVRGYKEGLVLIFDCVTEEWTRGPDLPELVQRAAC
VCVEC
>Sgl24341 E3_adaptor/Cullin_RING/SCF/F-box 19.4 0.0
MADHNKFHNIQSNEDLLVEILARLPVKSLIRFTCVCRYWQSLITSPSFSKTHYATRLRLL
RNRTQGDDDHDSLLSTFTNGCSISIFSYEDLSYKTAFKFRPYVHVPKPLRFGVCHCHVIS
DCKISGPCNGLFLVTLSKGLHELVLLIWNPATRRAFKVPYVEGIGHCNGFGFDSNSNDFK
VVSFNGTRNKGGVVLVYSLTANAWRQVDAGFRFGNFDMSMGGDTCTTNNGGMHHWTICDV
RYLREYLVSFDMVHEVFVETPMPSSYLSLMKKGSNHMYPLVYESDNRNNPTGINIWMVKE
YGRTGSWVKLQYIALPREVMGFGSSLLMWRNNEGIIYVSYTEGQGGLCCFNLTTKEVKVL
GVPSELWSFIGYTESLFSVTNFAQHQQPPFVYQNEAECSTLGTEDHVDAAADDDDGDDDD
SSTDSAFITPEGALNSPYDEIYVDCDEDAESCLRKENECQRLSKLPYCFREVNQPISYNT
CLF
>Sgl24416 E3_activity/RING/RING 19.1 10.2
MRTSGGAVSKRSVSGNRHVRVKGMESEDSDEDYVAELEEVDDQSDELNSLVGDASEEDSC
FEAGEEEEEEEEEVGWRRVVKTRARKEEEEDEGGWRRVVKTRAMKESTVRRKNGMKMPNR
KRRVKSDDDEDSDDDDEEFTPEEEYLEEEEEEEDEEEEEEEEEYCLRETTSRKRGRRTAL
KKNDSAKSQRKRSVKAARKASTKKRKKPSILRRQAKSDGDEDFVGKGPSLRGRNRKKTLR
RKKRMTAGSESEFCSDSSDYEFTISEEEREQIREANMICGSLRPNLRSSRRIQEDEIFYE
PKKAPPRKGKEKAEVKKNDVVKPVCGICLTEEGKSTVRGTLNCCTHYFCFACIFEWSKVE
TRCPLCKQRFVSISKPARCGRGFDLRDTVIPVPERDQVYQPSEEELRDFLNPYENVICTE
CHHGGDDALMLLCDLCDSPAHTYCVGLGREVPAGNWYCDGCRPAAVMSSQSQTPDITLDQ
RSSTGFSDGTSTYENMAEIDLNVTIPETPISQGVLSSPRFSGGSLQAPSPASGLGVSTVS
GRRMIHEQIRHILSNRLSQLSPGADISALRNRINRGVNSTQQLSRTTDVGPSHHAQYVDS
LQENPSISVQNRNSFPGRMGRMVRQVGQPSTSANSSFHSQTHWTGLDGIDLGEGQNQISA
GEHLRPCTGRPSMGHEIATSPSHNRFEENASFVKQQVHTMVRSQLKSLSRDMNLGHNDYV
EILRRSAHTIMATYGLEPRRHDTYNAQPPICLHFNSRLANVEASPINGCCLACFEAFAKD
VVKMILDIVMQPPHWFGFNINT
>Sgl24430 E3_adaptor/Cullin_RING/DCX/DWD 95.1 4.9
MSSLSRELVFLILQFLEEEKFKESVHRLEQESGFFFNMKYFEEKVQAGEWEEVEKYLSGF
TKVDDNRYSMKIFFEIRKQKYLEALDRQEKSKAVEILVGDLKVFSTFNEELYKEITQLLT
LTNFRENEQLSKYGDTKTARSIMLVELKKLIEANPLFRDKLVFPTLRSSRLRTLINQSLN
WQHQLCKNPRPNPDIKTLFTDHTCNPPNGAVAPAPVTLPVAAVAKPTAYPQLGAHGPFQP
TAAAANANALAGWMANAAASSSVQAAVVTASSIPVPQNQVPIIKRPRSPPATLGMVDYQT
PDHEQLMKRLRPAQSVDEVTYPTSRHQPSWSLDDLPRNVAFTLHQGSPVTSMDFHPTHST
LLLVGSSNAEITLWEVGSREKLASKPFKTWDMSSCSLQFQTALVKDVISINRVAWSPDGN
YLGAAFTKHLIHLYAYSGSNDLRQHLEIDAHVGGVNDLAFAYPNKQLCILTCGDDKLIKV
WDLTGRKLFNLEGHEAPVYSIRPHHKETIQFIFSTAFDGKIKAWLYDNTGSKVDYDAPGN
WCTTMLYSADGTRLFSCGTSKEGESYLVEWNESEGAIKRTYTGFRRKSNGVVQFDTTQNH
FLAVGEDHQIKFWDMDNVNLLTQTDAEGGLSSLPRLKFNKEGNLLAVSTAADGIKILATA
TGLRLLRTVEAPPFEGLRTPIEAAAIKNGSMEKPRLVEDATETKIKPWQLAEIVEPAQCR
FVTLPESMDSFSKVARLLYTNNGVGILALGSNGTQKLWKWSRSEQNPNGKATASVIPQHW
QPNSGLLMSNDVSGVNLEDAVPCIALSKNDSYVMSAAGGKVSLFNMMTFKVMTTFMPAPP
ASTFLAFHPQDNNIIAIGMEDSTIHIYNVRVDEVKSKLKGHSKRISGLAFSTNLGILVSS
GADAQLCVWSIDTWDKRKSVTLQLPASKAATGDTRVQFHSDQTRLLVFHETQLAVYDASK
MECIRQWVPQDALSAPVSYAAYSCNSSLIYASFCDGNIGVFDADTLKLRCRIAPSAYLSQ
AQMNGSQAVYPLVVAAHPQEPFQFAVGLSDGTVKVVEPTELEGKWGVSPPADNGMLNGRT
ASSSATSSHTPDQIQR
>Sgl24460 E3_activity/RING/RING 26.7 3.4
MGLDESDLIDDGDGRGKSLSSSNVSCSICLELVTDNGARSWAKLQCGHEFHLDCIGSAFN
IKGVMQCPNCRKIEKGQWLYATGCRSFTDIMDDWPHDEDLYDFSYSEMFGVQWCPLPAFS
RLPTFEEGEFPSTAYHDFLGQHAVFAEHTAVSSSTHQCPYVAYYGPMHSSSSSSVGSVSD
GSSFNSSWGVPSRPSEMPASYAFPAMDPHYHGWEHQSLSFSANNNRLGGSDQPSAPSLTP
RSSRSNSDLPRSGSYVHPFVVSNSSGGRVGSSVTSSMIPPYPGSAARSRDRVQALQAYFQ
PPSTSPPMRAPIMPSARRSSSHRGLSQGAPLPSSSDQTAGGFFMFPSGTSNRSFPEADNP
VSSRFHGWERDHLASFPVTPGDRDSSWLPHHAAGGSSSIRQRHGSERPPSYNWS
>Sgl24510 E3_adaptor/Cullin_RING/DCX/DWD 20.7 4.0
MPTSEQQQQQLKSISFNQDSTCFSATTTSTFHIFNTHPFSPAFHRTFPFSLSSIHMLFRC
NIFALVDSHSHKLFLWDDHRSSFISELSFRSTVLSVRLRNDRIIVVLLHKIFVYNFIDLK
LLHQFHTVSNPNGLCEVSSLPNSFVLACPGLQNGQIRVEHFGPNKTDFISAHHSAVASMA
LTLDGALLATASTRGTLVRVFSTSDCSLLQEVRRGTDRAEIQSLAFSSNARWLAASSDRG
TVHVFNLKLDSGSPGNSGLPSPTEQPTSPRSPISSISFVKGVLPKYFSSEWSMAKFHLQE
GTRYIVTFGQQENTVVIVGMDGSFYRCTFDPVSGGEMTRVEYHNFLKPENSKEPAES
>Sgl24523 E3_adaptor/Cullin_RING/DCX/DWD 20.7 4.0
MPTSEQQQQQLKSISFNQDSTCFSATTTSTFHIFNTHPFSPAFHRTFPFSLSSIHMLFRC
NIFALVDSHSHKLFLWDDHRSSFISELSFRSTVLSVRLRNDRIIVVLLHKIFVYNFIDLK
LLHQFHTVSNPNGLCEVSSLPNSFVLACPGLQNGQIRVEHFGPNKTDFISAHHSAVASMA
LTLDGALLATASTRGTLVRVFSTSDCSLLQEVRRGTDRAEIQSLAFSSNARWLAASSDRG
TVHVFNLKLDSGSPGNSGLPSPTEQPTSPRSPISSISFVKGVLPKYFSSEWSMAKFHLQE
GTRYIVTFGQQENTVVIVGMDGSFYRCTFDPVSGGEMTRVEYHNFLKPENSKEPAES
>Sgl24555 E3_adaptor/Cullin_RING/SCF/F-box 19.8 0.0
MRCSCCGDEEDEQDNFLHKPLLSPSPPQSIIFSKESTISPMNSNFSALTCRDILRIIFQK
LPITDLARASCVCRNWNSVASDREIQTASFMAPWKLKQIVGNPSSGSFWKDNSLSKFAIS
HRIVRGDSVASLAVKYSVQILDTCG
>Sgl24570 E3_activity/RING/RING 27.8 8.3
MTSLDLYLSMMKQEQQPNKDDQQLITSPNNSNPNPCPICLGFISQESYLDHCYHRFCYQC
IIRWIRVVSSRSSALQQASSIKCPLCKTENISIIHGYDGITFQRHFIDQINGNSKFFTKD
HKYRLLCYYTEPEQSMLSDAFKVERYWKSYKYLQQNIWLEKWLRRELQALMQEEDVEIIM
HHILGVIESFSRSHHPKGKLHLPQLKQEEFKVLVTNAATPFLTARTNRFFVELELFLASG
LNVEAFDRAYRRCLGWKKPEETSEDIEETNTERQPIAPNMYFFDDDEVD
>Sgl24613 E3_activity/RING/RING 27.8 10.9
MCHNKTCCNHTHHAIIFFLILSLLLLPNAPNLNFLLHKFTNSPSRPSSKGGDGDAGFLSP
PCTTTKMVTAFLYGAVFTFVLMFVSNYCNHNNNDHYQQDPSASAGGSQSIPIPFHRTTSI
GLASGRPTDDQGGAEGGGVGVGYALLRTFPTFAYSVRRPPTKLGKGTSVCVICQYKFKDE
ELVRWLPDCDHLFHLSCIDEWLTSHKTCPCCRADLDVITNNHGSTTTTSNGINTTPNYIY
DYFNEYSYNVFSR
>Sgl24616 E3_activity/RING/RING 60.7 18.2
MKFFHNDSTITIITTPIFLILLLGQTVAAQPSTTWPDSEQHEANFSPSMGVIIIALVAAL
FFMGFFSIYIRHCSNDTSTNGRTGRGIGSLRRSRRAPRGLDPEVIESFPTFDYAAVKSEK
IGKGALECAVCLTEFEDDDTLRLIPQCDHVFHPECIDAWLVGHTTCPVCRCNLNDASTTV
VGEEPPHEASIHSVDVELGVVEAESSNNEEERNDNNNESMEQPLHGRTISRNRTIRNLSF
GRPRWLGKHARSMSTGHVSVKQWDDMERFTLRVPQEIRKQIMSRKLERTTSLLVLPRETS
SRRGYRTGLGFGEGSSRGRFGSTRSGTSQSDRWVFSLAPPFITRAPSVKSPKVVETTTTS
RGGSLRAFLFLVGLLLSQQVRAQVHLIAPGLEPNSSTADHSSRRPPREVIIVAILSVLLF
VAFYFIYLCCCIDDNFNQIGNWSGWRHPWGALAASLRRHSFKSTENELDPEVVKSFPTFE
YGTIKSSMIGKDTLDCAICLTEFNDKDVLRLIPKCDHVFHADCVDDWLVGHATCPICRLN
LTNVDFWDDHDHHDYAVLEEGNESETLRMRSLSSSPQPTGLFEGLSRSLSTGHVSVKQWE
DKERYTLRLPWEVRKQIMSRSRSSGRFGSVNVDLRRGKSDSWVFNLTPSFRKQLNKVENV
SATSTSTSIKEESSINVSVDDEPTQLPV
>Sgl24617 E3_activity/RING/RING 39 5.5
MEATMSPEAFILYVSFYIVLSILSILWVCSIVCRSHWFFQGIRDHFIDDEPSIPLYLEHP
SLQTVVIEDLPKFSYSSQGIVDPRIDTSLRINTECVVCLGEFEENETIRMLPRCGHIFHK
DCIDIWLRLRFTCPLCRATLLDIVDMNPPQNRPSRAEV
>Sgl24618 E3_activity/RING/RING 36 5.0
MNDKSPLISYIMNIVFYIVLSILLVLWLLTIICRRHRALQTTSSQHRRQAVGPDHVIAFS
VNHELPPGLDTSAIETFPKFTYSGSDPVPGKMKMTGECAVCLGAFEEKETLRLLPKCGHV
FHAECVDIWLGIHATCPFCRAILLPPEDAASSGDRPTQFEVVINVNDGRER
>Sgl24619 E3_activity/RING/RING 31.9 11.2
MPSSSSSKQTVLYWITFSLLVAMATSIFAFLVFFLVTRLCLKRRRIGADVDPGSTVMEDP
YTGGPRGVDQTVIDTFPVITYTAVQGKKVCRGMNVCVICLAVFKEGETLRSLPKCGHVFH
SHCVDSWLKTHSTCPCCRASLVTRSGGFFSRVCWPSW
>Sgl24620 E3_activity/RING/RING 11.9 7.8
MKSHPKAIALGVVIIEIILCFLIYITCAIIRRRRRWRQQRQEQQRQYNEQQITRAISGDT
TSDSESVLVFIPYSIAKVSIEKIKVGLRCANCLNEFKDGEDETLRLFPKCRHVFHPLCLV
DPCSVTCQCCKTRSTKDDDDEAIKAEAKTDKEDEDEDENEDEDLARAEKVEDNNDKMVII
KLPEDVMQKIIVHAKLISQTGRPCSPTIFFRKKNNVELGEVVQD
>Sgl24628 E3_activity/RING/RING 34.2 13.2
MFRTSSERLVIGFALVIATVFLAVIFVILKLWRKSRLGRQVRADNSTGYSTSVGLDPSVI
ESFPVFKYSEVASNGAHTGPLECAVCLSPYEPDEKLCFLPKCNHVFHVECLHPWLKNHST
CPLCRINLVPVTSELNQV
>Sgl24629 E3_activity/RING/RING 40 6.9
MGIVLAIVTISVVVMFVVLNLCCQSQVGHEARASDGPSHRARKGLDPSVIETFPVFKYWE
VAARAHHTHSGPLECAVCLSQFEDDDQLRLLPKCNHVFHVECLDPWLKGHSTCPLCRVDL
VPEASDLDELDRIELGLASNGPGGEVNQGNNNNNVDCVSRDDIEEGYMGKYRRWKSMGHV
QVAEMVEGECWKRFTLMLPMKEMMSFGEVTNKFKRTKSSI
>Sgl24630 E3_activity/RING/RING 34.8 9.4
MFGASSDRLVIGFALVIATVFVAAIFVVINLWCKSQSGHQPRAHDSPGYRASDGLDPCVV
ESFPVYKYSEVAARSGPLECAVCLSPYEPDEKIRVLPKCNHVFHMECLHPWLKDHSTCPL
CRIDLVPKTSEFSQMESGQVNGLEDEVNKGGNEDNDAPLEARVDIEEGQGHFRKYRRCKS
TGHLAEIGRVEIECWNRFTLLLPEDEEAMKFGGVTNKFRRSRSSI
>Sgl24633 E3_activity/RING/RING 60.5 24.7
MVLSINHLQKLSLFLYFTSIFVTPLTVSAQYEDGHNNFQTASGRFVTAVVLLITTMIVAV
IFVVLSLCCKSQDGRRVRAENGRPGYRPNKGLDPSVIESFPVFKYSDVEARRQTHSDPLE
CAVCLSPFEPDEKLRLLPKCNHVFHVECLDPWLKDHSTCPLCRIDLVPETDEMDRVEPGN
GPAGETYQGRNDVDDMHEVRVDIEEGHIRKYKRWNSTGHVAEADRAEGECWKRFTLMLPE
KEIMKFVSAQDLNNNILGSNPVVSGVIFTIVAVFVFATLIVVNFCFQFQGGNQARADDGP
GQRARKGLDPSVIESFPVFKYSEVAAHQTQSDSLECAVCLSQFEHDEQLRMLPKCNHVFH
VECLDPWLKDHSTCPLCRIDLVPETIELDRADDMGLANGPDGVVINEGENDGNNNNVNEV
RVDIEEGGLGKFKRWKSMGHVAEGKMVEGECWKKFTLMLPEKEEMKFGDEVTSKFTRSRS
SI
>Sgl24634 E3_activity/RING/RING 46.7 14.9
MFHVDCVDPWLAGHSTCPLCRASLVPQPGETNDVESGRVVGLDCGPMEVNAADANNNVVE
AATHQEIGGTQSTKIWRWNSTGHVARFENRKEKSTEVTKVYRYLDRYYQQGWWAHETPNQ
AQLGLDPSTLETFPVFLYSDVSGLGDDKGPLECSVCLGTFEKDEKVRQLPKCKHMFHLEC
VNRWLASHTTCPLCRAELAHRPDDSTKTRLNSSDGSMNVSSAQAVTATVDDVV
>Sgl24635 E3_activity/RING/RING 33.2 9.7
MGLLAISVIIVLTILYYIANICYNSFLEQPSPELGPCDQVGLNPTILNDFPIFTYPNVAG
HIEPMLGPLECAVCLSPYKEEQFLRLLPNCDHLFHLYCVDRWLEANTTCPVCRADLIGEL
SQSSFGLIRSESSQVESTCTEELGNGLGIGYDNTPNENIVEMTQEILDWEATKIWRSNST
GHTTNSYEPEEDTERFRPTS
>Sgl24643 E3_activity/RING/U-box 23.9 1.2
MKLFHNDSTITIITTPIFLILLLGQTVAAQPSTTWPDSEQHEANFSPSMGVIIIVLVAAL
FFMGFFSIYIRHCSNDTSTNGRTGRGIGSLRRSRRAPRGLDQEVIESFPTFDYAAVKSEK
IGKGALECAVCLTEFEDDDTLRLIPQCDHVFHPECIDAWLVGHTTCPVCRCNLNDASTTV
LGEEPPHEASIHSVDVELGVVEAESSNNEEERNDNNNESMEQPLHGRTISRNRTIRNLSF
GRPRWLGKHARSMSTGHVSVKQWDDMERFTLRVPQEVRKQIMSRKLERTTSLLVLPRETS
SRRGYRTGPVFGEGSSRGRFGSTQSGTSQSDRWVFSLAPPFITRAPSVKSPKVVETTTTS
RGGSLRAFLFLLGLLLSQQVRAQVHSIAPGLEPNSSTADHSSRRPPREVIIVAILSVLLF
VTFYFIYLCCCIDDNFNQIGNWSGWRHPWGALAASLRRHSFKSTENELDPEVVKSFPTFE
YGTIKSSMIGKDTLDCAICLTEFNDKDMLRLIPKCDHVFHADCVDDWLVGHATCPICRLN
LTNVDLWHDHDHHNIPPFWRGQ
>Sgl24646 E3_activity/RING/RING 12.1 7.5
MATTATRDKQNKEYNEQQITRAISGDTTSDSESVLVFIPYSIAKVSIEKIKVGLRCANCL
NEFKDGEDETLRLFPKCRHVFHPLCLVDPCSVTCQCCKTGSTKDDDDEAIKAEAKTDKED
EDEDEDEDEDEDEDLARAEKVEDNNDKMVIIKLPEDVMQKIIVHAKLISQTGRPCSPTIF
FRKKNNVELGEVVQD
>Sgl24693 E3_adaptor/Cullin_RING/DCX/DWD 15.2 0.0
MKLQQTKGINKTNGFTRNSFKFISSCIKTVSTGVRSASASVASSITSDSNGVKDQVLWAC
FDKIELSPSIFKRVLLLGYTNGFQVLDVDDASVVTELVSKRDGPCTFLQIQPFPAESEGS
EGFKASHPLLLVAAGDETKGPDPTQRRRDGLVRDGYVESQTGNVVNSPTAVLFYSLRSHN
YVHVLRFRSAVLTVKCSPRIVAVGLASQIYCFDALTLENKFSVLTYPVPQMAGMGMVGIN
VGHGPMDVGPRWLAYASNNPLLTNTGRLSPQNLTPSPGVSPSTSPSGGSMVARYAMESSK
HLASGLISLGDMGYKTFSKYCHELLPDGSSSPVTSSSGWRVNKTLANSSDTDIAGMVVVK
DFVSRAVIAQFRAHTSPISALCFDPSGTLLVTASIHGNNINIFRIMPSSSKNGAGSHNYN
WTSSHVHLYKLHRGITSAVIQDICFSQYSQWVAIITSKGTCHIYVLSPFGGECGLQVDNS
HVDGPTFVPVLSLPWWSTSSYTVNQQSFSAPPPSPVTLSVVSRVRTGNSGWLNTVSSAAS
SAAGMGSVQPSAVSAVFHCSMPKGLPPRRSNALEHLLVYSPCGHLIQYGLIPSMGMETTD
TVSRNGSGVQDEDLKVKSEVVHWWDVCRRADWPEREECIKEMSFGSKDPSGTVLETSDSE
DGNSHGKGEELHEQSTLYLSKAEVQMNYGRIPTWQNSKIHFFSMNSMIPDRQKYSVDDDF
GGEIEIEKVPNFEIEIKRKDLLPVVEHFHKLKPDWSNRGAIGERYPNSTSEAHLAEDKYP
SPAVVHPQPVQNSQFGPFGQATEMDKVKSYLGIAQNQIIKNGAIAPSTFPKPILTQNSLK
TDNISAMEISPPENSCIVNSPSPVNNESLSAERANRKEVQSSSSVGGSEDSNVSSNRSDF
SMNVADESSVQDPLEFGGYFQEEYCKAAPLDENHELSEVVTDVDSSSSPRDKEKSEEDGE
SDELLGCVFAFSEEG
>Sgl24694 E3_adaptor/Cullin_RING/DCX/DWD 14.7 0.0
MKNQQTKGINKTNGFTRNSFKFISSCIKTVSTGVRSASASVAASISSDSNDVKDQVIWAC
FDKIELSPYNSKRVLLLGYTNGFQVLDVDDASFVTELVSKRDGPCTFLQIQPFPAESEGS
EGFKASHPLLLVAAGDETKSPDLTERRDGVVRDGFIESETENVINSPTAVHFYSLKSHNY
VHSLRFRSAVLTVRCSSRIVALGLASQIFCFDALTLENKFSVLTYPVPQMACVGMVGINI
GYGPMDVGPRWLAYASNNPLSTNTGRLSPRSLTPSPGVSPSTSPSSGNVVARYAMESSKH
LATGLLSLGDMGYKKFSKYYHDLLPDGSNSPVTSSSGRRVNKTSANSPESDNAGMVIVKD
FVSRAVIANFRAHTSPISALCFDPSGTLLVTASIHGNNINIFRIMPSCSKNGAGTQNYNW
TSSHVHLYKLHRGITSAVIQDICFSQYSQWVAIISSKGTCHIYILSPFGGECGLQFENSH
VDGPTFVPVLSLPWWSTSSYTINQQSFSASPPPPVTLSVVSRIRTGNSGWLNTVSSAASS
VAGMGSVQPSAVSAVFHCSRPNGLPLRRSNFLEHLLVYSPCGHLIQYGLIPSMGVETTDT
ASKTGSASLLQVQDEDLKVKSEVVHWWDVCRRADWPEREECLKDVSFGTNDPSKMVLQTS
ESEVTDNHGKVEGLHEQSTLYLSNAEVQMNYGRIPTWQNSKIHFFAMDHAVPNKQKYSID
DFGGEIEIEKVPDFEIEINRKDLLPVVEHFHKVKPDWSNRGAIGETNPTTTSDARVAEDK
YPSPAVIHPQLTQNSQFASFEQAAERDMVESYLGIAQNQLIKNGAIVSSTFPKPIPTQNS
LKIDNTSPMEISPPENSCVVNSPSPVNNKSLLAERSHRKEAHSSGSVVGSEASNVSSNRS
DFSMNVVDESSVPDPLEFGGYFQEGYCKAAPLDVSHELSEVVTDVDSSSSPREKKSEEDG
ENDEMFGCVFAFSEEG
>Sgl24709 E3_adaptor/Cullin_RING/DCX/DWD 56.3 2.2
MATEQMTDYERKRLENIKRNSEMMASLKIHSHISDLSSTTKHLREEKSYKQRSVKKPKVE
TPVVIRRSLRIQELPPDSIGLPEDCNDLPVTSSKPKALKMSSSPELRPLPREDLSMEITY
EGQKGSHLALVEKLARFTRKTKSDDEVKHLNSSKKLKFEKVDVVEPTNPCSLKLDNDNVA
NITPRRSTRNTKSDGLNNHSNSPLKPERVKLEEPFDPCNGLLNSPTMFERVKLEEPIDLR
SMELEHYNIARVVPGRIFSIRLFPTTEMTMVVVGNKNGHLGFWDAKPQSGEEEDVIHLYK
PHSAPISGISVHPFTLSKVYSSCYDGLLRLMNIERENFELIYSSSSGFFSLAQKADDVSS
LYFGTGSGELNMIDARTRDISSSWPLHEGRINTIDFSPQNTNFMATSSTDGSACIWDLRN
MNVKIRDKHPDLNVVSSVRHARAVHSAYFSPTGSFLATTSLDDKIGVLGGANFEETFMIP
HDNWTNRWVSSFRAVWGWDDTHLYVGNMKRRIDVLSVTQKKLVYKLESSNMTAIPCRYDA
HPCNAGMLATATSGGQVYLWTASS
>Sgl24752 E3_adaptor/Cullin_RING/SCF/F-box 35.7 0.5
MKRTMTSPPNLPPKKSKFNQPLKINDPNSNPNPIPISDSDSPESQFTKLDENLLYEVFKH
ADAKTLATASCVSKQWRLTAQDERLWELICTHHWSNSVNCGTQQLRSVVLALGGFRRLHA
RYLSKTAVTSPTSPPTPSVFPTLSTTAASSSSSSSSIQRQVVKRNGSKRWGKDEVNLSLS
LLSISFYEKMNSAYKKQ
>Sgl24764 E3_adaptor/Cullin_RING/SCF/F-box 14.6 0.0
MELESPQKTHLKSSLKTPSSLSLSSSFPEEVLEHVLSFIDSHSHLNSVSLVCKAWYEIER
WCRRRIFIGNCYAVSPSIVIRRFRDLRSVTIKGKPHFADFNLVPDGWGAHALPWIAAFSE
AYPSMEELRLKRMVVTDEALELIGKKWRSFKVLVLCSCEGFSTEGLASIAANCRNLKTLD
LCESEVDDLSGNWISHFPDSYTSLESLNVACLVSELRFTSLERLVSRCPNLKSLRLNRSV
PLEKLPILLEKAPQLIDFGTGSFLTELNTEAHEKLSRAFAGSKGLKSLSGLYDVIPTYLP
ALYPVCSGLTSLNLSYATIHSPDLIKLLSHCQSLQRLWVLDYIEDSGLEVIAESCKDLRE
LRVFPSEPYVQEPNVCLTEQGLVSVAMGCPNLQSVLYFCRQMSNEALFTIAKNRPNLTRF
RLCIIEPQVPDYLTNQPLDEGFGAIVEHCKDLRRLSLSGLLTDRVFELIGAHAKKLEMLS
LAFAGDSDLGLHHVLSGCNLRKLEIRDCPFGGSALLVNAAKLETMRSLWMSSCQVSYGEC
KLLGRKMPRLNVEVMDERGHPNSRTDDCSVEKLYIYRSIVGPRADSPDFVCTMSEDLASP
LRCTE
>Sgl24776 E3_adaptor/Cullin_RING/DCX/DWD 109.3 26.5
MYAIKFSSAGVTIAYNLRDPVQLVKIEELKFANLSKISVRWNLLAMHRVGSAGNTSGSNR
PRKEKRLTYVINASDDTKHCAGVNCLAVLKSNGSDRSECLFTGSRDGTLKRWTIDEETAT
CAATFESHVDWVNDTVLVGDHTLVSCSSDTTLKTWNCLSDGLCTKTLRQHSDYVTCLAAA
GKNSNAVASGGLGGEVFVWDIEAALAPVSKSNDSTEEDASNGVSGGGSNLPITSLRTINS
SNSISLHSPPNHGYTPTAAKGHKESVYALAMNDSGTLLVSGGTEKVVRVWDPRSGSKTMK
LRGHTDNVRALLLDPTGRYCLSGSSDSMIRLWDLGQQRCVHSYAVHTDSVWALASTTSFS
HVYSGGRDQSLYLTDLSTRESILLCTEDYPILQLALDDESIWTASTDSSVHCWPAEGHNP
QKMFQRGGSFLAGNLSFSRARASLEGSTPVPVYREATLKVPGIPAIVQHEILNNRRHILT
KDTASSVKLWEITRGAVIEDYGEVSFEEKKKELFEMVSIPAWFTVDTRLGSLSIHLDTPQ
CFSAEMYSADLNISGKPEDDKVNLARETLKGLLAHWLAKRKQRSGSQSSANGDVQSVKDV
SARNMTHSRSEVDGSVENDTMIYPPFEFSTVSAPSIITEGSQGGAWRKKITDLDGTEDDK
DLPWWVMDCVLNNRLPPRENTKCSFYLHPCEGSTIQILTQGKLSAPRILRIHKVINYVVE
KMIQDKSDTPGDGTFAPSLAGGPLQLSTTGDGSLRSGLRSWQRSRPAIEILCNNQVLAPD
MSLATVRAYVWKKPEDLVLHYRVMQGK
>Sgl24779 E3_adaptor/Cullin_RING/DCX/DWD 109.6 26.5
MYVEELKFANLSKISVRWNLLAMHRVGSAGNTSGSNRPRKEKRLTYVINASDDTKHCAGV
NCLAVLKSNGSDRSECLFTGSRDGTLKRWTIDEETATCAATFESHVDWVNDTVLVGDHTL
VSCSSDTTLKTWNCLSDGLCTKTLRQHSDYVTCLAAAGKNSNAVASGGLGGEVFVWDIEA
ALAPVSKSNDSTEEDASNGVSGGGSNLPITSLRTINSSNSISLHSPPNHGYTPTAAKGHK
ESVYALAMNDSGTLLVSGGTEKVVRVWDPRSGSKTMKLRGHTDNVRALLLDPTGRYCLSG
SSDSMIRLWDLGQQRCVHSYAVHTDSVWALASTTSFSHVYSGGRDQSLYLTDLSTRESIL
LCTEDYPILQLALDDESIWTASTDSSVHCWPAEGHNPQKMFQRGGSFLAGNLSFSRARAS
LEGSTPVPVYREATLKVPGIPAIVQHEILNNRRHILTKDTASSVKLWEITRGAVIEDYGE
VSFEEKKKELFEMVSIPAWFTVDTRLGSLSIHLDTPQCFSAEMYSADLNISGKPEDDKVN
LARETLKGLLAHWLAKRKQRSGSQSSANGDVQSVKDVSARNMTHSRSEVDGSVENDTMIY
PPFEFSTVSAPSIITEGSQGGAWRKKITDLDGTEDDKDLPWWVMDCVLNNRLPPRENTKC
SFYLHPCEGSTIQILTQGKLSAPRILRIHKVINYVVEKMIQDKSDTPGDGTFAPSLAGGP
LQLSTTGDGSLRSGLRSWQRSRPAIEILCNNQVLAPDMSLATVRAYVWKKPEDLVLHYRV
MQGK
>Sgl24787 UBD/Alpha-Helix/UIM 13.3 0.9
MKHIFKKLHKSHDLNRTNNETLTSSSSSSSSQSQPSTSNSSSSSSSSSATAASTTAAAGV
TAASTATATATATTQSQSQSVEVGYGGVGNSANVKNDHHNLRQGDYFSSEEEFQMQLALA
ISASNSEFRDDSESDQIRAATLLSLGGANSVDNARDKELSGETLSRRFWVSSSILLCLFV
CLCMMN
>Sgl24831 E3_adaptor/Cullin_RING/SCF/F-box 15.8 0.0
MKMVSCKSSASNTTPIIPNDVIVCEILPRLPVKSLLRSKAVCKDWYDLISTPQFIKSHLQ
LSLFSSPRFFTMNDQGHWRKFYTFTYNEGRSNRKEWVHLDSSAWTDELVHRNKYGIIGCC
NGLVCLSVQHNKKHEDGTTTLSFIVWNPATQECREISPPTEDGRLLCWSGFGYTLAHDDY
KIVCILSDCVWIFSLREGQWKQIMGFPSYDKPMFKGVFVGDVLYCKVVSSLEETDANIIS
LNLVKEQFEEIPLTNLPIANVVSISLYVIKGCLSVHSEVEPQDVWMLKRQDDWKSWEKVF
RFPSNIIVNHKGITWDGKILADHWGKLVLVDPNCNSLTDYMESADCYCPDDFWGWPYGAE
TPQHVESLVSPFGVAQDVNGSKAYV
>Sgl24833 E3_activity/RING/RING 20.1 10.2
MSTQVVKVRRDKVAACMKCPICNKLLKEATTISLCLHTFCRKCIYDKLSDEDVDCCPVCD
VHLGCIPVEKLRPDHNLQDIRAKIFPLKGRKVEAPEIAPAVSAPVKRKERSLSSLVVNTP
RVSMQGVVTGKRTRAGRKGSVPRSASPATEETNKKEEDSVEDHLDGSSSPETLNKIIQNK
KQSSSTKSSNDQTRGEGMENNNEGREGKVDLWKPLNTLVEAANRSKFSKSNVQGASHSKA
DASNSGDADIGVNKTRTDEIGQGDESEGDKSGNPPVSGPVKRNRLRPSNKNRSSVPAESL
SSQVVVNEARQNWKDGPIWFSLVASEEQEGGEPLPQVSAAFLRVKDGSMPVSSIQKYIMK
KLELASEAEVQIMCEGLPVMPHLKLSSLLEAWLRTSATQKKIQTTVGDSAKEFVMVLSYS
RKVVAPNS
>Sgl24837 ULD/UDP/UFD/PB1 59 0.0
MLSSERDKYTIDFEETELRLGLGLGLGLAGSGSCEVDQLAKNNNGKRGFSETEGDSSVDL
KLNLSTSTTTTATNTTTTTTNTTTTSNIVKDVKVEQSVTSSVADQKLKDKVTPADPAKPT
PAKTQVVGWPPVRAFRKNIVSVQKKSSEEQSDQKASNNAVTHAAAFVKVSMDGAPYLRKV
DLKLYKSYQDLSDALGKMFSSFTIGNCGSQGMKDFMNESKLIDLLNGSDYVPTYEDKDGD
WMLVGDVPWEMFVGSCKRLRIMKGSEAIGLAPRAVEKCKNRC
>Sgl24838 ULD/UDP/UFD/PB1 63 0.0
MEMNKKDSTQHEDTELRLGLPGTEFKTTQIISNNKRSFSEINKEESTSNDDDKSTKITAP
PPKAQVMGWPPVRNYRKNCLQAIKKEAENNGGVYVKVSMDGAPYLRKIDMKVYKGYPELL
KSLEDMFKVKVGEYTEREGYNGTEFVPTYEDKDGDWMLLGDVPWEMFTNSCKRLRIMKGS
DARGLGCLA
>Sgl24839 ULD/UDP/UFD/PB1 63.4 0.1
MEKSNINLSYHHEDTELRLGLPGTTNNGSEKKRSFSEINEESTSGVEDCHDDHLLSQQKV
QAIGWPPIRSYRKNCLEVTKSREESTRMYVKVSMDGAPYLRKIDLKLYKDYNELIKTLED
MFKFKTGKLCNKEAINNGSEYEATYEDKDGDWMLVGDVPWEMFTSSCKRLRIMKGSEARG
LGCCLA
>Sgl24939 E3_adaptor/Cullin_RING/SCF/F-box 17 0.0
MKMVSRKSSSSTTTPTIPNDVIFCEILPRLPVKSLLRSKAVCKDWYDIISTPQFIKTHLQ
LSLFSSPRFFTMNDQGHWCKFYTFTYNEGRSNRTEWVHLDSSAWTDELVHRNKYGIIGCC
NGLVCLSVQHNKKHEDGTTTLSFIVWNPATQECREISPPTKDGRLLCWGGFGYTLAHDDY
KIVCILSDCVWIFSLREGQWKQIMGFPSYDSPMFKGVFVGDVLYCKVVSSLEETTDANLI
SLNLVNEQFEEIPLTNLPTANVVSISLYVIRGCLSIHSEDEPQDVWMLKKQDDWKSWEKV
FRFPSEIIVNHEGITWDGKILADHWGKLVLVDPNCNSLRDYMDSADCYCPDDFWGWSYRS
EIPQHVESLVSPFGAAQDDNGNKAFV
>Sgl24970 E3_activity/RING/RING 18.3 1.8
MLFQVGGQGTRPTFFEMAAAQQLPSSLRSALTYSLGVMALRRPILHRVLDYEDEFFALLM
LVLETHSIRTTDASFSESLYGLRRRAVNIALKKDTLHSDSTNGVQHSGMEKHQKILSVVF
LVVLPYFKSKLHSIYRRERETAVQESLWGPGGEGFDGVDYLDVAENPVDQTASDLELSSR
ARILQGVTKVITACYPLIHAGHEGLAFAYQTLYLLDATGFYSLGLHALGIHVCRATGQEL
MDASSRISRMRSRERERLRGPPWLKKLQGALLSCMYAVLDYSQTGLIAAVFVFKMMEWWY
QSAEERMSAPTIYPPPPPPPAPKVAKEGIQLPSDRTICPLCSERRANPSVVTVSGFVFCY
GCIFKYVSQYKRCPVTLIPAEVEDIRRLFHDM
>Sgl24974 E3_activity/RING/RING 18.2 14.3
MEIGQSSSSKSSDEVWAKLVPSDSSYASIEISSDDATVCSQISSTSDKLEWCQIIRNSDR
CSATIRNKRTSLILVDGTTLMGDDVVGLKCGSEIVPASTREGQLSYKFEVMPVQEQCPEK
YLKISLDAENTKCGICLNVWHDVVTVAPCLHNFCNGCFSEWLRRCQEKHSSVLCPHCRAA
VHFAGRNHFLHGIEENILQADASLRRSAEELAVLDSYASIKSNLVVTNGKKNRRKRAHSP
TPIHEETDGVDLPCPQCGTQTGDFRCNASTVHLQCHDCGGMMPLRSDINIPQHCLGCDRA
FCGAYWRTQGVNRTDLRPICSSESFRPITNSCISQTGKTLQEIISEWTIKFNNREIDRSR
LLVRHGEMIAAGTHVCNECFDKLVSFFLYWFRISLPVHLLPPEASNRDDCWYGYACRTQH
HSVDHARKRNHVCRPTRGSHT
>Sgl25003 E3_activity/RING/RING 31.7 8.0
MENNDQVRQPQEQQQQSQEQQQQSQEQQQQSQEQQQQAPKQISLDQLEQVESDHVFALAL
QQQESTTTFTMLETIESDSTDDDVLDDEDEEEEEEDEEIGSSSSHDFDTQEFYGELEYLE
EDEEGSYIDDEFEEDEIDPDEMSYEELMALGEVVGEESRGLSTEEITSSLSSYVHKMVQC
KTIIDRCVICQSEYEEGEHLAALHCQHPFHEDCINQWLQIKKVCPICSIEITPTVPPSSN
PDIPDKI
>Sgl25026 E3_activity/RING/PHD 38.2 5.7
MAESPIKAKKRLDLKSPTKPSNSPISFLPPQTPNTDFNSSPIESTPLRRSSRRLSQNAND
FKLTPEKSVKQSLIKTLEKSPKTPKSSKRSKLSSPHNQKVLNEDPIHPKSPALTEERKRK
RGNELGDVAKTRAQVRARAQNVPKKRVYYKKVVYDKAEFAVGDDVYVKRRENASSDDEDP
EVEECRVCFRAGQTVMIECDDCLGGFHLECLKPPLKEVPEDDWTCEFCEAKKLGKKVQLP
VPPKGMKRARTLKEKLLSSDLWAARIESIWKEVDRTYWFRAHWYMIPEETEAGRQPHNLR
RELYRTNDYADVEMESVFRHCYVMSPKEFAKAGNAGDDVFFCEYEYDIRWHSFKRLAEIN
DVEEDGDNDDDDSASDEDWKSTKDPESESEEDMDFEDENDKRKSFGPPSQELAANSRKGH
IFGLQKIGTKSIPKHVRCHKQTELERAKQTLLLATLPKSLPCRDKEMEEITKIIKDAISD
DQCLGRCMYIHGVPGTGKTMSVLSVMRSLKSELDSGNIKPYSFIEINGLKLATAENIYRV
IYEALSGHRVSWKKALNFLNERFSEGKQVGKGKNKPCILLIDELDLLVTRNQSVLYNILD
WPTKPNSKLIVIGIANTMDLPEKLLPRISSRMGIHRLCFGPYTYQQLQEIIMSRLKGIDA
FDKQAIEFASRKVAAISGDARRALEICRRAAEIADYRIKSHISLANPPSVGKTHVVMADV
EAAIQEMFQAPHIQVIRSSSKMAKIFLAGMVRELYTTGMAETTFEQLAVVVSCFCTSNGE
QFPGFDTLLKVGCKLGECRIIICEPGYRHRLQKLQLNFPSDDIAFALKGCPELPWLAKYL
>Sgl25057 E3_adaptor/Cullin_RING/SCF/F-box 12.4 0.0
MTTKRIIKPYNNFSTNNNPPPWDEHELPMDLLTSHILPKLPPKSLLRFKSVSKSFKTLIS
TPQFINNHCKNQNNNNNSDDDHMLIFLRRDDKCLHLSNLHSLKSWYIDLPWQYHHLKVIG
SCNGLLCLKLCNYSSHTYCLMFLNPTTLDYKQIPDCGYKYLDYDLTCGLGFECLHDDYKI
VVLIKGYYNGHRSINSFVYSLLSNSWRCIEGTPKDIVGCITNVFGPSVLIDHHLLHWRLY
IQDTNEHRIICFNICTQEWEAHIPTPRTNNNNEPVNGAKLIGLGVLDGCLSLVIETMESN
SSWVMKKYGIKESWVKIFDASHSSKVVASFLVFAPFDLLRGSKEEIWLRELDGSLIRYNV
IKNTFEKIDIQGIPICTCKSSLATTATGIEASNRSSNGVKRVRDGMIKLYHDQA
>Sgl25350 E3_adaptor/Cullin_RING/DCX/DWD 52.5 0.9
MASEQMTEYERQRLENIKRNADMLASLNVHSHLSNLRFREEKRRKYEKKPIQEASRTSLR
TQGIPPHFEGLPEEYNESLRPSKPENKAPEAVSFAGPLYMRDAYKGAGSHRTLVDKFTCF
KSVGPSFDHAGIVEAHFDFNSLKLEPRNVARVVAENTLAVRFLPTTSMTMVVVGNRDGEL
GFWDVGKGNEGDEAIHLYHPHAAAVSGISVHPFALSKVYTTSYDGFLRLMDIEREKFDLV
YSNTFGYCLYSISQPPNDPNSIYVGEGLGGLKVFDERARENVFSWCLHEQRINTIDFNLA
NPNIIATGSTDGLACLWDLRKMDVTQGNCKALHTVDLGKAVLSAYFSPSGSNLALSVDGY
ISVVCGANYEDLFTICERYRCHGSKVGHWATCPRAVWGWDDNHIFAGDSKRSINIVSVSE
RKIVYSLESPLMSAISSRYHAHPYTVGMMAAATGGGSVYIWTADL
>Sgl25741 E3_activity/RING/RING 28.1 10.5
MTSGKTNLVMTVIGFVVSTLFIVFICTRLICARIQLRTSRRNFRRHTASRSNLTTLEGGL
NGIQPPISANFPAKKYGDDYFSSAESGQCSICLADYQTEDVLRIIPYCGHYFHIKCIDLW
LLQHCTCPVCRLSLREANERKRSMQFMSSSRSHPNTDVPAVSPRHCRLMLRTPETHVIGP
IQEDQLLSNVIMNSTGDNNSQLPEENDPVKDPKKKNVESPSFA
>Sgl26042 DUB/USP 118.6 3.4
MSECAASQHDDDGNSLIMLESYDPEETITIYEKSLSSNTFLLPLHCSSSKCQIIHWRQGH
KHECHPQDHSASEKDDFDENADSHRHDDVLDLPVPCLSTVTVASFDTGRSSCGENETLSS
HIDATKMGHREDKINSMEMNASTGLTPNGAVNSVRKLKKKSRQDDRRKFRPSNSEHSPGS
QQDKSNRTFGNVPSSKAEEVLLVDNDEQKHSSYSVPPRRSVSNELSRNGLASSFQKVVHH
FKASNQKKPSPHDNLLGISANRNLIARYAVDTMQSVCAELAGVVGPKRDESTLVGMTFGG
FLHSKIRCLKCNNKSEKYERMMDLTVEIDGDVRTLEQALRRFTASEMLEGDKKYYCNRCK
SYKKAKKKLTIFQAPNILTIVLKRFQAGSFAKLKKPVQFPEILNMTPYMSDSSDKDKHPQ
YNLYTVDP
>Sgl26148 E3_activity/RING/RING 16.1 16.7
MMDVRSLQQKPESGTDDATAEFERGLEELMRGHLDDCMSFTSCSSTRNTLDEDEDQEGDQ
LMRRRRRSDLAESSAARRRHSRILSRWAARQAQEMITTLERRNRESELMALAGLHPVSML
DYSFLRESQSQSQTLRRQGGTVERPSSRASAILQMWRELEDDHMLLNRARERVRERLSHG
SVVDSSTDVSTITTSEDREGENLGSVDDASESEHDFREWSHDQMQTRNDHVVSSSGEQSP
DLGEVERERVRQIARGWMESGTNERSSDITPRSNNNPREEWLGETERERVRVVREWVHMA
SQQRTRGGHDEDQRAVDSQADRVQGDVINSEEVEVQPEHVRRDILRLRGRQALIDLLMRI
EGERQRELQGLLEHRAVSDFAHRNRIQSFLRGRFLRTERITEDGRPPSVAASELLQLRQR
NTVSGLREGFHSRVETNIQGQERSDYVVSTGDRESGFPGDQAQQGNPDQLHPRIQGDGVT
ELANFVVNVPHEASANAITVEQSSIQRGNWQQQVAGDERRDLPQSNFAELDHSRSNPQEN
MVGDWQETPGNVMQRSTHLIDGEEESHLPGQQIWNDNGSRATQASWPGGWSNPPRIRRGI
PIRQINRFNRPDDDNVYSMELRELLSRRSVSTLLHSGFRESLDQLIQSYVERQGRASIDW
DLHRNLPVAAASLHDQDSQPVESNVSDTVNRRPLVIPSPPMPPLQPLWQQGLHQANWSRH
GMHRSELEWEMMNDLRADVARLQQGMNHMQKMLEACMDMQVELQRSVRQEVSAALNRSTG
GKGAETSEDGSRWGHVSKGTCCVCCDDYIDSLLYRCGHMCTCLKCANELVRGGGKCPLCR
APIVEVVRAYSIL
>Sgl26188 E3_activity/RING/U-box 41.7 0.0
MASENLGLVPSQRMENNNLNSQLLFQNSNNPLRFGRGPENPVSKSGYVDDKLFSMDHRER
GYFSPELRRADDGVGGVYEEGPTSERRGRGDRDRTWNHREPASTPSSEEEEDDDDDDDDD
DDEEEDDEEGKNSHSSSGVGGANSKDHAPFGSSTRKMMIKDGVILQPASDANRVSTSENE
QQGRLGNFQKMVTVAEHDGDMYYLQLLHGTEGSSQGQKDLAVDNGSGLNGRKDSYVSSDP
GESLRAIFSDPITGALMDDAMILPCGHSFGSVGVQQVIKMKACYTCSHSVAEDSVAPNLS
LRAAVQAFRREEDLQMYKASKRRRERFEQEKGNYGDSCFSDLPRGKGVQFPFSVTDRVII
KGNKRTPPRFVGRQAIVTTQCLNGWYVVKTLDNAESVKLQYRSLEKVQNISSSTPISDKV
IPNWL
>Sgl26308 E3_adaptor/Cullin_RING/SCF/F-box 15.8 0.5
MDITPWISMLTQESKEGRYLNWQSSATYRPVILRIGNAHFIPASHSHAHQLSFSMLKRFP
PIFIEVEPAAITGLASSESENMSEHPTADSSPLVDAPRLSLPPGEKQVDHPTAVITTDEM
NFNPIDLITPVRVPGLKRWNFFPFPRPPGERTSDDLPPSDDPFDKSITSMPLDILHKIWS
HFTDETLSVGVVVCREWGQEIPEFIHHSPLMDPERRAALVDGWFPDFPLPSQYPPPYTLP
VQEGVSFCESSSDEEDEPETKYGPMRLPGHLPATWVEVNGVWGSDDEDVYIDQVAPTPVD
QACQEVAIDPNWYMNSDDGKEVQVLTRSGRLQNPDSQPPAPGNPQPPPQPPKEENPLIKQ
LQKVQTDISIWDLLTSSFEHRNKLLDALSQMNVAPDTTPDELVGLLTADHSRTTISFSED
DLPPEAINVCPLRTAETLGIDVSNITGTSQGVKAYDNTRRSSLGTVSLSIATGPVERRMT
FHVLDIKANFNLLLGRPWIHDLRAVPSSLHQKVKLIVGGKPITLEATPMSIYVNAIQVEH
DENDEDLWGFDAETAMVELAPSSALFTNPVKG
>Sgl26439 E3_adaptor/Cullin_RING/DCX/DWD 64 3.5
MGTMSLNHLDDDTVRSMSIGAVFSDFGGQINSIDFHRTSDLLVTAGADDSVRLYDIVNAK
LLKTTYHKKHGADRICFTHHPSSVICSSKYNIDSTGESLRYLSMYDNRCLRYFKGHKERI
VSLSMSPINDSFMSGSLDHSVRMWDLRVNACQGILRLRGRPAVAYDQQGLVFAVAMEGGA
VKLFDSRSYDKGPFDTFLVGGDTAEVCDIKFSNDGKSMLLTTTNNHVYILDAYAGEKRCG
YSLEPSPNTTIEATFTPDGQYVVTGSGDGSMHAWNINMQSEVGRWSSHIGVASCLKWAPR
RVMFVAASSVLTFWIPYNGKNTGESNAKDADATDKMEVLPH
>Sgl26540 E3_activity/RING/RING 41.9 13.5
MLFLNRPLVGINATRRRRTYHFFWCRQCNKTIRIVSTISSTFICPFCYDLLFQELCPLRS
SIFPSHNFLLFLSSSSASHAQLIDTISRINNISSSQPRPTSIPPQESMLSIQHEPQTIEN
KTCLGITKFRIMSSDILCFEQTCPICKEDFVVDEQITKLGCNHLYHSVCISPWLQINMTC
PLCRYKLPTHQGCSQHDHNNRARRSSNNFRVLTQLFSFLWPFRLGSYLDRLFPS
>Sgl27280 E3_activity/RBR 143.3 40.5
MRKNHHQRIKQTGEESDWIVKPLSEGNKEKAAHIDFDIDVDVDDHDVEVEHSQTCSPSNS
NSKSYDGIKFRWVSRNVEKSAKNEVGVSSAAEYEVGQSSSDIGQKNEVGESSFDERETGI
RERKCGVDEEKIVVGSQVGWTEEEGGGDGIVRRLDELQFGVELELSEEQIQINDQAQQDE
LLAMESIYGKNVSVLEKRQGLRSVQIHIHIVLPSAYTVSAKFNSDTNADSKFSDGDEFLY
SFKVQYLSPIILTCLLPRSYPSHCPPSFTVSVQWLHENKISELCTMLDLSWNEQSGKEIL
YHWVEWLHSSSLPYLGFDEELVLGPCHMLTAPDRRALSGSISSDIDIPSMKSYDEDRQHE
NFLSGFHQCYICFSEYAGTEFLRFPCHHFFCIKCMKTYADVHVKEGTVNKLQCPNTKCGS
MIPPGLLKRLLSEEEFERWESLMLQNTLDSMPDVTYCPRCETACLEDEDQHALCSKCFFS
FCTLCRERRHVGIACITPELKLQILKDRQNSPLLKDEQRRKVLDMINELQSVKEILRDAK
QCPSCKMAISRTDGCNKMECSQCGQYFCYRCSKAISGYEHFREGKCELFPEDDLFPPEQQ
WEERINARQVMAQIQAQVFNGNARPCPNCRQLNAKVGNNNHVFCWACQNHYCYLCRKTVR
RSSEHYGPKGCKQHSVD
>Sgl27555 DUB/USP 276.8 2.0
MAFLQMNWQPNHHHHKRKYAAPLGLKNLGNSCYLNSVLQCLTYTPPLANFCLDYRHSSFC
DLASDPERKRDCPFCIIEKRIVRSLSIDLTLDTPSRLVNCLRIFAEHFKCGRQEDAHEFL
RYVIDACHNTCLRLKKLQLQRAKKITNGSGGETSGGNTIVKEIFGGSLQSQVKCLSCGTE
SNKVDDIMDICLEISNCSSLKDAMKKFFQSEILDGNNKYKCERCKKLVEAKKQMSILQAP
NVLVVQLKRFEGIFGGKIDRVIAFEEILVLSSFLCKASQDPHPEYSLFATIVHSGYSPES
GHYYAYIKDAAGRWYCCNDSFVTLSTLQEVLSEKAYILFFTRTGQRPVSADTEVMSNGIK
PSETNGSNMSKSPMKTMNLKSSNAPSLVKGISVASKNSDAVILQNKFSGITNSLAKRVSG
SDNGITDILKRESAGVDGNSKNSVAKRLNVEKTHSSEDSNGNCRNGEHSDNENHRNGEHS
DNGNRRNGEHKENGNHRNGEHKENGNRRNEEHNDNKNCRNGESNAVASSQVIVNGGTHLK
NGTLGLVKGSIHENNGTGMLLDNGTIHNGHSADCVDASGPKRKLENRETADKILENGQSH
KSSDVSSSKRRFEDRGTCILLAKDAQSQSRVEEFKEFLKKEAALLLQTCGWSDDVYKYMR
SKKRVHNDACSSIDNSEQK
>Sgl27592 E3_adaptor/Cullin_RING/DCX/DWD 31.1 0.2
MASGLCKGRFMNEVESLCGHTTPVESLAFDSAEVLVLGGASSGTVKLWDLEEAKSEFVYV
LHFIYPPFVRWVVSGGFDNVVKLQLQPSQVNYHSDLVSVRVTLSMSVILRETRLGKGKGN
AGGSSQKGGAEEEKYWDLSGLSLKGTLAPELGILHTNHLSGVIPAEFGRLTKLEVLDLSD
NNFTGVIPTDIAKIVSLKRLLLCGNNFEGIIPPEFEEYSSLIAVSLKFDLKT
>Sgl27623 E3_activity/RING/RING 10.5 13.6
MGNKLGRRKQVVDEKYTRPQGLYQIKDVDYKKLRKLILESKLAPCFPGGDDCDTGILEEC
PICFLYYPTLNRSRCCTKSICTECFLQMKNPNSTRPTQCPFCKTSNYAVEYRGEKSKEEK
GMEQIEEQKFIEAKIRMRQQQQLQLEEESNHRTEDTLSHMDPRTENIGCSTIGGIECEES
APSLDSSGAQMFRQPQNTRHGRDDEFDLDLEDIMVMEAIWLSVKENERGGHLPYDDALPE
PYTVEDHYMSSAAAPVTGSSTSPSGGLACAIAALAERQQLTGESSSNNYSGSISPLDMLP
SSSSRSSKRMKKTQRKPTEISSTEEICSSRVLADACEVGPASEIAEVGPSYVDSDDSDSE
AVIPSYRGRWNSKRGKNIQRKLSKNMHGRRMVAEEWEYDRVAEAGTTRANSDDSDEDLQA
AILPPPPPPLPPYEMIGSSSGSCGAQDHGDYLLPPPPLPYVSDCGFQSSVPGPIVPENFE
EQMMLAMAVSLADSRTRTTAQGVTWH
>Sgl27627 DUB/USP 258.9 0.0
MLEPRQADIPALFLVLVVLPVVLYILLGKWSEASNKKERINLVVEEAFVESFRPDVMAAV
SVIPPVVPPLSTSFRECARCHGPATTRCARCKSIRYCSGRCQIIHWRQGHKEQCQPPDDI
YSSSNSASVEEADSETDFNQKGVYHQFNGCPSQFPGANSTDASPADTSASVDACQMLKHE
RTISEKRVSRKAKELLDTENEAYSRPKLRVGNSTNTEDGLSEIDCISGSVTCDKYTGRRG
ALQQSPGVISQTKHSPPSAESGMNVKEIASPYREANCNAKVSKRSNLSQMVSNCEDIGSR
SPIASDSAKSMPRASREQLKLEKVRKGNGLVKSVHGMGNFTSTHETNSIASVGLVKAAGV
KKSSKITKNAASDMVINNWKKVKVLFPFEEFTKFFEIEVFNLVPKGLLNCGNSCYANAVL
QCLTCTKPLVVYLLGQTHSRTCSLNTWCLMCELEQHVHMLRDTAGPLSPSRILSHIRSIN
CQIGDGSQEDAHEFLRLLVASMQSICLEEAGGENLIHPILQETTFVQQTFGGRLRSMVVC
LRCHHESERYENILDLTLEIFGWVESLEDALTQFTTPEDLDGENMYRCGRCTTYVRARKQ
LSIDEAPNILTIVLKRFQEGNYGKLNKCITFPEMLDMIPFMTGINDSPPLYMLYGVVVHV
DTLNASFSGHYVSYVKDLQGNWFRIDDTVVQPVPMSQVMSEGAYILFYMRSFPRPPRAFI
KNARKQQQTVKSSRSCVSKTQSSSKKGLDIHRSDSRFNQAMETRTYPDFMEFSDATTSDW
SLFTSSDEASFTSESTRDSFSTTDYIENGNVDPFSSMFGTHSTRDHQSSQRMVSCSMFSG
SKPVTRYVSEQTGYVLDSDHAVYPLDEMQMGDIMSQVSVPFNEAYLPNSEYQNFVNYEST
ASDSFIQTFTNVHL
>Sgl27809 E3_adaptor/Cullin_RING/DCX/DWD 110.1 8.2
MFDTRNMMHSDPSMPKMTDESDYSDRPSSFSAMGNSFIDEPTRMSAEMSPMMMSPWNQVS
PFAKSHWSQTSDNPSFGDSGQLNSLIGSLVREEGHIYSLATKGDLLYTGSDSKNIRVWKN
LKEFSGFKSASGLVKAIVIAGGKIFTGHQDGKIRVWKVSPKNPSIHKRSGSLPTLKDLFK
ASIKPSSYVEVKRHRSSLWIKHSDAISCLSMSGEQGILYSSSWDRTFKVWRISDSKCLES
VSAHEDAVNSVVASSEGMVFTGSADGSVKVWRREMQGKVTKHFFVQTLLKQECAVTALAV
DPTGSIVYCGSSDGMVNFWEREKNLAHGGVLRGHKLAVLCLAARARLVFTGSADKTICVW
RREGTIHTCLSVLTGHSGPVKCLAVEDDKDAVGQRYVVYSGSLDKSVKVWNVADQDAMGM
GIGMGMGMEMMPQQQQVMEVDSASESLRSDRSSQYT
>Sgl27825 E3_adaptor/Cullin_RING/SCF/F-box 17.4 0.0
MKKVRRSSRLERRGVTMKSEDMQNYCPFENIASDVIMKVFSFLPTKACLKCKLVCKAWYD
IITNREFANQRRAHGCYRSLLLQGRFSGSRKEFVLLDLDRSSKVVEEGNLTVGYLATLTI
KPNFGIPMGKLHLINECNGLICLKVSARWSPFIICNLLTGQQWTVKQTYKPNAFIYSCGL
GHFLRSDDSGQFKDYFKVLRILVSRKERCYVAEIQTLGTNEWRSVGKVPKVELGKAFLHG
SLHGYSNEDNCIWSFDCGEEKFSPVPLSDELKRKKVTGVSTLDSFLCCKTTTSGKEDLCE
IWIMKEYGNKDSWVKQFSFSLVKHSSDDGMPFLRMDSGEVMFRNPVVGCNYRSFLTVRDL
ESKTHMCVRFISDNPSEYCTSFGKYILNS
>Sgl27883 E3_adaptor/Cullin_RING/DCX/DWD 132.8 14.8
MLAMPNNNESALSVAGPRPMEWSTVPYSGSQAPGTNGRQRTSSLESPIMLLTGHQSAVYT
MKFNPEGTVIASGSHDREIFLWNVHGDCKNFMVMKGHKNAVLDLHWTTDGTQVVSASPDK
TVRAWDAETGKQIKKMAEHSSFVNSCCPARRGPPLVVSGSDDGTAKLWDMRHRGAIQTFP
DKYQITAVCFSDASDKVYTGGIDNDVKVWDVRKNEVTMTLQGHQDMITGMSLSADGSYLL
TNGMDCKLCIWDMRPYAPQNRCVKVLEGHQHNFEKNLLKCAWAPDGSKVSAGSADRMVYI
WDTTSRRILYKLPGHTGSVNECVFHPREPIVGSCSSDKQIYLGEL
>Sgl27889 E3_adaptor/Cullin_RING/DCX/DWD 125.5 13.5
MLAMPNNNESALYVAGPRPMEWSTVPYSRSQAPGTNGRQRTSSLESPIMLLTGHQSAVYT
MKFNPEGTVIASGSHDRENFMVMKGHKNAVLDLHWTTDGTQVVSASPDKTVRAWDAETGK
QIKKMAEHSSFVNSCCPARRGPPLVVSGSDDGTAKLWDMRHRGAIQTFPDKYQITAVCFS
DASDKVYTGGIDNDVKVWDVRKNEVTMTLQGHQDMITGMSLSADGSYLLTNGMDCKLCIW
DMRPYAPQNRCVKVLEGHQHNFEKNLLKCAWAPDGSKVSAGSADRMVYIWDTTSRRILYK
LPGHTGSVNECVFHPSEPIVGSCSSDKQIYLGEL
>Sgl27901 E3_adaptor/Cullin_RING/DCX/DWD 133.5 14.7
MLAMPNNNESALSVAGPRPMEWSTVPYSGSQAPGTNGRQRTSSLESPIMLLTGHQSAVYT
MKFNPEGTVIASGSHDREIFLWNVHGDCKNFMVMKGHKNAVLDLHWTTDGTQVVSASPDK
TVRAWDAETGKQIKKMAEHSSFVNSCCPARRGPPLVVSGSDDGTAKLWDMRHRGAIQTFP
DKYQITAVCFSDASDKVYTGGIDNDVKVWDVRKNEVTMTLQGHQDMITGMSLSADGSYLL
TNGMDCKLCIWDMRPYAPQNRCVKVLEGHQHNFEKNLLKCAWAPDGSKVSAGSADRMVYI
WDTTSRRILYKLPGHTGSVNECVFHPRERILGSCSSDKQIYLGEL
>Sgl27903 E3_adaptor/Cullin_RING/DCX/DWD 89.3 5.0
MLCLTFTGPLMEPRGPPLVVSGSDDGTAKLWDMRHRGAIQTFPDKYQITAVCFSDASDKV
YTGGIDNDVKVWDVRKNEVTMTLQGHQDMITGMSLSADGSYLLTNGMDCKLCIWDMRPYA
PQNRCVKVLEGHQHNFEKNLLKCAWAPDGSKVSAGSADRMVYIWDTTSRRILYKLPGHTG
SVNECVFHPREPIVGSCSSDKQIYLGEL
>Sgl27904 E3_adaptor/Cullin_RING/DCX/DWD 132.8 14.8
MIKLMRMDWALDEVSRAAVLLSCIVVPYSGSQAPGTNGRQRTSSLESPIMLLTGHQSAVY
TMKFNPEGTVIASGSHDREIFLWNVHGDCKNFMVMKGHKNAVLDLHWTTDGTQVVSASPD
KTVRAWDAETGKQIKKMAEHSSFVNSCCPARRGPPLVVSGSDDGTAKLWDMRHRGAIQTF
PDKYQITAVCFSDASDKVYTGGIDNDVKVWDVRKNEVTMTLQGHQDMITGMSLSADGSYL
LTNGMDCKLCIWDMRPYAPQNRCVKVLEGHQHNFEKNLLKCAWAPDGSKVSAGSADRMVY
IWDTTSRRILYKLPGHTGSVNECVFHPREPIVGSCSSDKQIYLGEL
>Sgl27937 ULD/UDP/UBQ/UBQ_PIM 540.4 23.4
MQIFVKTLTGKTITLEVESSDTIDNVKTKIQDKEGIPPDQQRLIFAGKQLEDGRTLADYN
IQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVESSDTIDNVKAKIQDKEGIPPDQQRLI
FAGKQLEDGRTLADYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVESSDTIDNVKA
KIQDKEGIPQTSRGQGRYPPDQQRLIFAGKQLEDGRTLADYNIQKESTLHLVLRLRGGMQ
IFVKTLTGKTITLEVESSDTIDNVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLADYNIQ
KESTLHLVLRLRGGMQIFVKTLTGKTITLEVESSDTIDNVKAKIQDKEGIPPDQQRLIFA
GKQLEDGRTLADYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVESSDTIDNVKAKI
QDKEGIPPDQQRLIFAGKQLEDGRTLADYNIQKESTLHLVLRLRGGL
>Sgl27980 E3_adaptor/Cullin_RING/DCX/DWD 15.5 1.1
MAMFKQGGWYGHGAIFSSIIIGSIFLCFFLQSSTAEQVNLTVEKFTVFGIAEKSNDNNTV
HFDLKMRNYNIRPIYYDALNITFYFKSNLSNSPIGNATFASFRLRKNRQDHLVGSFKAIG
MKWENATAPLAMFRVQVASAMRFGLKNNFFKSKRFRYVIKADLKVDNQGNLVNKGVELKS
SVGRNVKGPFEMIGILLGLKVNHSLFWVGSLELSDVLLQACLHVMWITDHYMVYLFYQSV
DSEIVLWEPIIKEHSPGEGSVDILQKYPVPDCDIWFIKFSCDFHYKAGNREGRIYVWELQ
SCPPVLITKLSHPYSKSPIRQTAMSFDGSTILACCEDGTIWRWM
>Sgl28065 E3_adaptor/Cullin_RING/DCX/DWD 95.8 8.1
MDLLCKTYSNNSDDDEEDDKPSQNIQPPLKRQKPLYPKPYFQVSDSQIRVSNSRIGAPDS
QIGAPVSGNGRYISKREKALMASSSSSSTNDVNYPTSFPPSTEMGSISRAHVRQDILLSL
RKQTTTFARKDKLPCKLSTDLHGHLKPVNSVQWSTNHAHLLASAGMDNCVYIWNVWSEQQ
KKVRAFRHHNAAVKDVKWSPEGKFILSCGYDCSSRLIDIEKGSETQSFTENQAVTAIKFH
PHNSNLFLSGGSKGFLKLWDIRAGKVVHEYVRRLGPILDVEFMSDGKQFISSSDVSQSNL
SENSLIVWDVSREVPLSNQVYVEAFTCPCVRCHPFETSFVAQSNGNYIAIFSTKHPFRLD
KYRRYESHGVFGFPIKCCFNMDGEILASGSSDGEIHLYSVRSSSLLKKIKVYSQPCIDVA
FHPVIPNVIACCSWSGNVSVIE
>Sgl28082 DUB/USP 187 0.0
MVETMELLRANLSRVRIPEPTNRIFKHECCVSFDTPKSEGGLYVDMSSFLAFGKDFVYWN
YEKTRNPVYLHIKQTKKVVPEDRPSKKPTILAIGVDGGFGSGEPEYEETYGIVILPDYAT
LPFPSVELPEKVRLAVDAILLAEGAERKEQIATWVAEKQVSAYAMNLQQIDNGIVVSPSG
WKCSKCDKTDNLWLNLTDGSILCGRKNWDGTGGNNHAVEYYNETKYPLAVKLGTITADLE
AADVFSYPEDDSVIDPLLSQHLAHFGIDFSSLEKTEMTTAERELDQNTNFDWNRIQESTE
ALQPLFGPGYTGLVNLGNSCYLAATMQLAYTTHAFSSRYYENQDLKSAFNAAPADPTVDL
NMQLTKLGHGMLSGRYSIPSSEKQEGIPPRMFKTVIAASHPEFSTMRQQDALEFFLHLLE
QVERVNVGNPKLDPSRNFKFGIEDRIQCPSGKVNYNRRCDYILSLNIPLSEATNKDQLEA
FQKLKSQAELDGKDIDTSEVVRPRVPLEACLASFSAPEEVMDFYSTALKAKTTAKKTTGL
TSFPDYLVLHMRKFVMEDGWVPKKLDVYIDVPDIIDISHMRSSGLQFGEELLPESADDEA
EATKILANQEIVSQLLSMGFGQIPCEKAAINTGNVGVEEAMNWMLSHMDDPDINDPISSH
TSQNAAASVDQSKVDTLISFGFQDEVARKALMASGGDIEKATDWIFSNPNASSTSDMDTS
SSSAVAADAELPDGSGKYRLLGFVSHMGTSTHCGHYVAHVYKDGKWVLYNDEKVGASVNP
PKDMGYLYFFERVTG
>Sgl28170 E3_adaptor/Cullin_RING/DCX/DWD 67 9.3
MSKNTEQEQEEEEEEEKEDYTNHHRSINHFDYNSSIAPQQQQQAVVVVEEEQEEERFFES
LDRILSSSNSSTSNSEDEIDTIATSLAVIGRITVIITAAISFSLSSLEQRRDRLLKALGL
SSDTGLARRRSGAVRSVSFDHHFGGCSTELPTKFEDDGFINRSKSDQCNSSAYSSSPCSS
ILSIRSVCDTVNRDSKSYIIISGLGGLDKSEAVRSGSSDGIGAVEGGCGGGEKICKSGGQ
VDEFESDKVCTIKNLDTGKEFVVKEVREDGMWNKLKEVGTGRHLTMEEFEMCVGHSPIVQ
ELMRRQNVEDQLNNGKDNGDCNGNGDNGSKSKKKLSWRSSDDRDTSSEKVVVGQALLRMI
VRIPHSMDQRGLGFGNMEIQLRWKVLGKCWRGLCDTCWQVVESERKGELLMDKPDDASLS
LFLMPSGSPEPNSVSSSLDNPLEKKRRGRPSISRKSVSLDPVRVPEIIFGLSEKPICSFQ
GHSDDVLDLSWSKSQLLLSSSMDKTVRLWNLSSKTCLKIFSHSDYVTCIQFNPVDDRYFI
SGSLDAKVRIWSIPDRQVVDWSDLHEMVTAACYTPDGQGALVGSYKGSCRLYNTSENKLQ
QKCQINLQNKKKKSHLKKLLVSRLELGTTPIYSVGLEIQSVSFVSSFRVVDGSDLVHKFK
GFRNTNSQISASLTTNGKYVVCASEDSHVYVWKHEAESRPSRSKGVTVTRSYEHFHCQDV
SVAIPWPGIGELLGPQELCSEEQTEVHHPLDEVLTVNHPPTPVEEFNGNDSSPSASGRSN
SPFRGTISSAPNSYFFDRIS
>Sgl28212 E3_activity/RING/U-box 30.4 0.3
MAIALDSLTIPLASSFSSSPFSTSSSSSLSSLSISLKFPEFKGLKASSTVAVRSVSSHSK
IVRRSTRIACENSDTAFQLPSVTDETWKSLVLESDLPVMVEFWAPWCGPCRIVQPVIDEL
SKEFAGKLKVFKVNTDESPTIASDYGVRSIPTVIIFKKDILFFFKKKKLKYCQNFKDMDL
IQNFQNFTAECRSEDDATVKQDCKSGLSPTTEPESSQGSFDCNICFDLAHEPVVTLCGHL
YCWACIFKWLHVQSSSSQSTPHKACPVCKANISQSSLIPLYCHSPPRAQDGSGKSHYDVI
PPRPTAVNSSSNRHLSPNPFESRYPEFHYGNYASISSLNHVSPTMAGIINPTIELLGELV
YTGRLGSTDAGSFAFPHPNSYAAVGNNSNPRMRRQELQVAESLNRVSIFLFACVFLCLLL
F
>Sgl28242 E3_activity/RING/RING 39.2 6.4
MAFIGAPQPWLSPSPSSTPPPPFNAFDDKNEDCSLPLCSNKCPQFCLVLPPPPPFVFNNN
PSYDYDDDDSPYRISPLMVALISVLSAAFLILFYYTVISRLCRNHRRRHNNNRLLNPNHV
DSLIPDQTQPETAATSGLDDSFIQKIPVFNFRKSDKLIDATECAICLSEFDEEENLRLMP
NCEHAFHIHCIDEWLKSNSNCPLCRSSMNPPPVSSISVLYSI
>Sgl28254 E3_activity/RING/RING 32.9 8.2
MDKSYNGELFYIAGIGLFLNLFLFATTLIIYLCKPRNENTDLESFDHVQYYYEDDHLSVP
LLDEEEEEEKGLRLINCIPSMKFIQKVSNKGEDEESSRANGCSICLIEGYEDDEMIKVLP
ECNHVFHSCCIDQWLKKKQSCPVCRKVFRVVLPKV
>Sgl28256 E2/UBC 79.8 0.0
MESGLIRNSKKSFLDESSSSSYNKPNIVAIHSESELSEQISVGGHEVILVDEEQHDNVVI
VDEKDASFGSNTIVGHEVVAVDEDDAVVFDEKDAFNDKGKKLLVNKFAGQEVDTPDEVIP
SPQASEIVEAEAMAPKLSASASASASAAREKHAVPESSCFKEDHPKAMKSKSFFKSLFSK
RCFMPKFACFGSKLRSFNRRASASHVEMHASPSTFAAVQTPPIAEAGDVHFHLDQGLKLD
DFHPNSAEFPPPSTDGQSNSSQDSILKKLELFKNFDISEDHFGHSFEVINECSNPSNEWV
KYIADEWKMLEIGLPEAIYVRVYEARMDLLRAVIIGANGTPYHDGLFCFDIQFPSSYPKV
PPAVKYHSHGLKINPILRPSGDVCLSLLLGTSDVVENEYWRPYQSNMLQVLVSIQGLVLN
AEPFSDDPDVPSNQTSHKTRSENTYIDSLKSMLYTLRSPPKGFEDLVQGHFYMHAHDILE
ACRAYLDGVEVGSYVKGNPQATASENIENCSEYLNMMLPHYINLLVKAFTKIGVKDCEKY
SIPEEFF
>Sgl28257 E2/UBC 93 0.0
MALSFASIMEDPTIQLHPLQNSRKRKFASSGSSSNSSMVEPDLIEIPPPATWKSKPQKQK
SVAGCELIVLDDTEDTDDVIVIDEKIAPKSKGKKPMHNYLSGDSIPANNGPLSASVKDSM
KGASSSGVSFIDDSFDFAGMDLAGSHYDSECALLQAHFDSIDIPSGVEATVPWWAFSPEI
IEPPVIPSSSAAITNQSNSFVDTSEVDGFQSWAYSPGIVEHSVIPSSSVGISNHSNSVVE
TSEVDRFQPLGKVKPVSFKKKTASKKFLHGSKHPFSGHATYPMPYAQTSGMFPPHNGWPS
VPGQGPNFAFDHDPFGSKGFPGWQNASHVYPSPVPFLSSVASSNSISKLSNGNMHVPQFL
DPVRLDDGISSQISPPFSQEQGDGSENSIVKKLEVFKKFDTLEDHSDHFFLKNKESGSQA
KNSWLRKLADEWKMLERDLPGTIYVRVYEARMDLLRAVIVGADGTPYHDGLFFFDVHFPP
TYPHKAPSVNYHAHGLRLNPNLYNCGKVCLSLLGTWSGSGVENWLPGKSNMLQVLLSIQG
LILNAEPYYNEPGFANSKGNQHGRQQSKNYSENTFLLSLKTMLYTMRNPPKHFEDLVFGH
FYTRAHDILGACRAYLCGVEVGSYEKSKPAARSKGSNCSQLLLKNLPTYIKSLVEAFTKI
GVKDCEKFLVPVENVANQPARGSSASRAKGRKFLASYVPPWNHV
>Sgl28266 E3_adaptor/Cullin_RING/DCX/DWD 97.3 14.3
MEGSSNTGWRKSASSRGLETSVSSERNLRLLHASRRSLSTDASRNAFGSGRSTKDAAIGQ
SPSDYLRNRLGSSGVSEDEVAMDPVVRSIEWGDVSLRQWLDNPERSVDTIESLHIFRQIV
EIVSTAHSQGIVLNNVRPSCFIMSSFNHISFIESASCSDSGSDSLEDGMDGQNTETKQPC
SSLCHDLPEQRSRSAHKDTHLMTETSGSKSHSLLATNVASTEERGWCEAKDSRCSRKAGE
KQSFPMKELLLMETSWYTSPEEIAGAPCSCASDIYRLGVLLFELFCTFSSFEEKSGTMSS
LRHRVLPPQILLKCPKEASFCLWLLHPDPCSRPKMSDLLQSEFFNEPRDDIVEREAAIEL
REKLEEHELLLEFLVLMRQAKQDAANKLHNTISFLSTDIEEIVNKQKAIKQKGGTFSGPE
RSHQSELDLPPINTSEHEMDHTDTGQGTQIHGVSKFSFDQSESQSQESLLSKNSRLIKNF
KKLESAYLLTRHRPARMSGKPVGGHSHLSSNSRGSVVLNEKSSSVSLSKECKNNSGESGW
ISPFLDGLCKYLQYTKLDAKADLKQGDLLNSSNLVCSVSFDRDGEFFATAGVNKKIKVFE
CDTLLSGDHDIHYPVVEMACRSKLSSICWNSYIKSQIASSNFDGVVQVWDAARGQVFMEL
KEHERRVWSVDFSSADPTLLASGSDDGSVKLWSINQGASIGTIKTKANVCCVQFPSDSGR
TLAFGSADHKIYYYDLRNPRVPLCTLIGHNKTVSYIKFVDSSTLVSASTDSTLKLWDLTN
CASRVVEGPLQSFTGHANVKNFVGLSVSDGYIATGSETNEVFIYHKAFPMPALSYKFNTV
DPLSGNETDDGAQFISSVCWRAQSPMVVAANSTGDIKLLEMV
>Sgl28312 E3_adaptor/Cullin_RING/SCF/F-box 22 0.0
MEAAFNPSIALPFPYSNYGITNVPTFNPSFPHPPHHHQTTTITSLLPPFFTTTTTPTTTS
TTTTINWMDPRIWSRLPQPLLDRILAFLPLPAFFRARSVCKRWYALLYSNSFLQLYLQVS
PTHNWFIFFTHKTPNTSIIYRNNTTTNNNDNEGECCNGVSSSTSTRAYVFDPYELKWYTI
SFPLIPLGFSPTTSSGGLVCWASDQPGLKNLFLHNPLVGSVAQLPPTRKPRLFPSVGLSV
TKSSIDLILAGDDMISPYAVKNLTSEMFHIDSDGFYTLWDPTSALPRLCSLESGRMVSSL
GPRYYCMNYSPYSVLAYEVASNMWWKIQAPMRRFLRSPCLVEINNGHKKVVLVAAVEKSK
LNVPRSLRMWVLQECGTQWVEIERMPQQLYAQFEEVEGGRGFDCVGSGEFVAIIIKGVND
STNNKGLLFDLNNKRWVWMPCCPRNHEISSNYVEGDLHGYGYQPTLVAPVTSLVQQLGAL
HHQSFTG
>Sgl28320 E3_activity/RING/RING 14.5 0.2
MASTSTARAIAGAATRIKDATSSLSSDNQPLISDIRKALNSMKEIAVEMEKLNRSQEVRE
LEDAFMQLLETFDESMNFSNVMQSVGNTYQPGPELTDFKKLFQSEVSKLKGGSTSNRQTN
ALLRQFKEAVWNVHHAGQPMPGEEQEDIVMTSTQIGVSNTVCPITGKSITELAEPVRSMD
CKHIYDKEAILHVIKNSTKRCPVAGCPKSLHATRVVCDPLLLVEIEELRSQNTNTVQLES
IIEDCTALEDED
>Sgl28342 E3_activity/RING/RING 30.8 4.1
MNERDMMCSTQRVLDLTSGQQVQSHLHPEPCIIMGSTSNIPRLHVNQVLPPSGSVNNFDF
HRLPEHVGRPAFYAMPQYNQHNHPATNHSNFMNLHLDPAPGARVFPVPISHGFADHLPSS
SNYGANAVPFNEHVRSNYPAEGVRDLCKRKNTDGIPGNIQHLGASAGPSSSSGAAMTNCH
FDSGSAYMDALPMTDYRGNGAPPMMEVGARNRSGGVGLHMDSGVHNYNNYLLQANYGGQS
FEPSSCTWVDQQSISNAGSLPWSGPHPMMSYFQGSNVHGGSSELANSSRSGYLERSSNHG
SANFLPTPPVVPQHHSLHPSQNIQGMGGYGVACYPPFLAAPTRVPPSDGMQHDVLSLSQE
SAEQANRPTGLRIYRSQGRNVVPDLASRRRDLPRLRTLQADSVALLEFSNYYEVDYNVEN
FIDHHSDMRLDIDDMSYEELLALSERIGTVNTGLTEKDIICHLKTKLYNSTGATFNLEEL
PSIDQDSDSCIICQDEYEDNDKLGTLDCGHDYHVDCLKKWLLLKNVCPICKSRALAVNQG
NK
>Sgl28348 UBD/UBC-like/UBD_UBC 164.6 0.0
MTNDGEKSASPKSSIPPSNDYHPANAVSNIKNEVPEILDREKANYSNWVELFQIHCHSCN
VLDHIDPKLSRPTDITEAQWNRLDSIVKKWIYNTITPDLRSTVLYPNATAQETWDRLKNL
FQDNKEMRAIYIENQFNNLFVKNFPDVASYCQKLKELKDQLANVDQCVSERQLVLRLVAG
LIDSPYDGVAQSIAQVKPLPSFDEARSRVLLEESRQQAKENSAQSFLAQSPATNTPAIST
PPLPSPSPQQQGRGGGGRNNRGRGGRFGRGRGRGRGNYQQQHTGQQNPSWASQSPPQLWA
PYNHMPQQQHWTTPPCPYPTSPAGPRGILAAAPRHTGPPPQAYFSGPSHYPSLMHPTEFA
QAYSSPGFANTDDGWYMDSGATSHMTNNSGTLLPLFKLGTPNYILVGNGHRIPISGYGHT
TLSNNNLALRDVLYAPHIIKNLISVRKFTSDNHVSIEFDPYGFSVKDLRTGTIITRCNSL
GNLYPVTTSSPSPSPPSALTALSSSTWHDRLGHPGAASLGLLRSKNLISCTKEHASTFCN
SCPLGKHVRLPFYNSNTKTLSAFDIIHADLWTSPIRSSQNHKYYLVLLDDFTHYVWTFPL
VSKAQAFQTFLHFRQYVHTQFERPIKSFQSDHGREFDNDPFKLFCVKNGLVFRFSCPHTS
SQNGKAERMIRTINNIKRTLLFHASLPPNFWNHALETATYLLNILPTKTLNNLTPHQALF
RKTPYYDHLRVFGCLCYPNLSSTAPHKLAPRSTPCVFLGYPPNHRGYRCLDLSTNKVIIS
RHVQFNEQNFPYANIGKYTLKEYDFLDDGAGLNLLTHLIMRYPPNPHKTSTHAIAQSDHA
TSSHVAHVPSHDLAQPTHSPILTTGPPQQLTTSSAHSTSPSSHAQFTSSSHRPTANHTYT
PPPKRGFTPITPTRPPPLSPQMQTRAKHAMANSNLPRRIIKETQRLLSEPAPGISASPSE
DNMRYFNVMILGPSQSPYEGGVFKLELFLPEEYPMAAPKVRFLTKIYHPNIDKLGRICLD
ILKDKWSPALQIRTVLLSIQALLSAPNPDDPLSENIAKHWKTDEAEAVETAKEWTRLYAS
GA
>Sgl28391 E3_adaptor/Cullin_RING/SCF/F-box 13 1.1
MSLSRSFLSRNRSSIRCFSLSSKSHKDHHHQTSSSSSSFSLPTSDFLHHHSSDATVNRNN
EFVVEDDDDGGRWSSLLPELLTDIISRVESSEDKWPLRRNVVVCACVCKRWRDITRQIVK
SPLATAKITFPSCLKQPGPRDVPLQCLIKRDKKNSTFFLYLSVSPSSFADKGKFLLAARR
YRRGAHSEYIISLDADDLSQGSQAYIGKLSSDFLGTNFMIYDSQPPHNGAKPSSSRSTRR
FASKQISPQVPAGNFEVGQVSYKFNLLKSRGPRRMICSLKCPPSPGEANLDQPEEAKIKL
SELDSIYTVLRNKAPRWHEHLQCWCLNFHGRVTVASVKNFQLIATVDQSQPGGKGDEEVV
LLQFGKVGDDTFTMDYRQPLSAFQAFAICLTSFGTKLACE
>Sgl28408 E3_activity/RING/RING 14.4 0.3
MQVRELEDAFMQLLETFDESMNFSNVMQSVGNTYQPGPELTDFKKLFQSEVSKLKGGSTS
NRQTNALLRQFKEAVWNVHHAGQPMPGEEQEDIVMTSTQIGVSNTVCPITGKSITELAEP
VRSMDCKHIYDKEAILHFIKNSTKRCPVAGCPKSLHATRVVCDPLLLVEIEELRSQNTNT
VQLESIIEDCTALEDED
>Sgl28431 E3_adaptor/Cullin_RING/SCF/F-box 12.9 1.1
MSLSRSFLSRNRSSIRCFSLSSKSHKDHHHQTSSSSSSFSLPTSDFLHHHSSDATVNKNN
EFVVEDDDDGGRWSSLLPELLTDIISRVESSEDKWPLRRNVVVCACVCKRWRDITRQIVK
SPLATAKITFPSCLKQPGPRDVPLQCLIKRDKKNSTFFLYLSVSPSSFAEKGKFLLAARR
YRRGAHSEYIISLDADDLSQGSQAYIGKLSSDFLGTNFMIYDSQPPHNGAKPSSSRSTRR
FASKQISPQVPAGNFEVGQVSYKFNLLKSRGPRRMICSLKCPPSPGEANLDQAEEAKIKL
SELDSIYTVLRNKAPRWHEHLQCWCLNFHGRVTVASVKNFQLIATVDQSQPGGKGDEEVV
LLQFGKVGDDTFTMDYRQPLSAFQAFAICLTSFGTKLACE
>Sgl28486 ULD/UBL/ATG8 165.4 0.3
MSKSSFKVQHPLERRQAEAARIREKYPDRIPVIVEKAEKSDIPDIDKKKYLVPADLTVGQ
FVYVVRKRIKLSAEKAIFIFVKNILPPTAAMMSAIYEEHKDEDGFLYMTYSGENTFGAL
>Sgl28490 ULD/UDP/UBQ/UBQ_PIM 104.1 6.6
MDVIFVAPKESFTIEIGYFDTVLEIKEKIQKYRKIPISQQILIFNGKILEDNGDVDSCVI
LHKSIIHLRISTPKSQSVEIHKQPQENLRLKNHSSSYNYNKNNKKIKYNNFNDFNFIHHS
SNNNNPDVISSKKVEILIHLPTSQNGINTDLVIDVDLNDSVEQLKRRIHHSEGYPAHLQA
LYINKRNVELQDNRKLYECELKNGSEIDMLIRLPQIPAPPPPSMMNEVSTVNSKKLKVIV
VTKCGTMKLPVEVNPFDKVQVLRKKLEKLQQKVKFELPEEGYFFIYKQRVMEEKETFRGY
RVRQDDTIDIFNGSVTGGQ
>Sgl28498 E3_adaptor/Cullin_RING/SCF/F-box 13.4 1.3
MPAFMNLFGFAAKQEAHTTTDTTHTATAEVEREIVCDGEVCKALDRRSSVKTSSIPPELR
SSKKNEKPLLESEEHEKPDVEPSPAEKPESPAAETTAQKSCTTNGSQPIFCRILALLRLR
KFSTRCSLPTPTIAELTISAPTVQTA
>Sgl28512 E3_adaptor/Cullin_RING/SCF/F-box 17.2 0.0
MWADLPRDILFYIVRYVDMKVDLPRVRGVCRSWRTALNLDELPRRDPHTIEVPNLEGIEI
ECYLRINSSPLFLLESRFYFISPVISSESAGTSNCNRGGWIARMCEAKTETGTGINNRWH
LLNP
>Sgl28513 E3_adaptor/Cullin_RING/SCF/F-box 14.9 0.0
MWADLHKDILFCIVRYVDMKVDLPRVRGVCRSWRYALNLDELPPRDPHTIEVPSLQGIEV
DGYHLTSSTLSSSWKVDSTSFHL
>Sgl28515 E3_adaptor/Cullin_RING/SCF/F-box 17.2 0.0
MWADLPRDILFYIVRYVDMKVDLPRVRGVCRSWRTALNLDELPRRDPHTIEVPNLEGIEI
ECYLRINSSPLFLLESRFYFISPVISSESAGTSNCNRGGWIARMCEAKTETGTGINNRWH
LLNP
>Sgl28516 E3_adaptor/Cullin_RING/SCF/F-box 15.5 0.0
MLDFRVLELARSYSLVNDKDNYNATDLSKKVVGGWDYTSSYRFAALVQPDFKGHLLLLWR
LGDQQWLKVVESTISVPDILLPSPKHMSGVDNGVSPFRNTFNLLPSKSKGCLYLVLEDFL
NEGNTEGGRPSLEEKEKGDVPFDEMPKEEQELYLGLFFPPPAWVKWRCPTLDNVEVRLLH
KTVEMWADLPRDILFDIVRYIDMKVDLPRVRGVCRSWRTALNLDELPRRDPHTIEVPNFE
GIKIKGFHLTHSGPLFLLESRFYFISPVISSESAGTSNCNRGGWIARMCEAKTESGTGTG
INNRWHLLNPLRNNHAYYHGNIDYLYVEPPITGTINMLDFRVLELARSYSLVNDKDNFNA
IDLSKKVVGGWDYTSCYRFAVLVQLKIDGHVCKNLLLWRLGDQKWLKVVGKKVVWIFDIA
FLNGKFYIFEQLFDQRRVRVLNPRNPLVLESTISAPDILLPGPKLLSGVHGVENERKWKE
MENLCDEIFFIGHDVAFALPSSSQNLPQWKQNSVCTFFDVDTFYYFDGYSHKTEMPEGAE
YLDSVMYQSYNRYLSLFNLEEKEKGNVPFDQMPKEEQELYLGLLFPPPSWVKWHCPTLDV
EVRLDGLRFHEEEEVEEGEGEEDSDEEGEEEGGGEEEEEEEEEDSDD
>Sgl28518 E3_adaptor/Cullin_RING/SCF/F-box 14.4 0.0
MWADLPRDILFDIVRYIDMKVDLPRVRGVCRSWRTALNLDELPRRDPHTIEVPNLEGIEI
ECYLRINSSPLFLLESRFYFISPVISSESAGTSNCNRGGWIARMCEAKTETGTGINNRWH
LLNPLRNNGTYYHENIEYLYVEPPITGTINMLDFRVLELARSYSLVNDKDNYNATDLSKK
VVGGWDYTSSYRFAALVQPDFKGHLLLLWRLGDQQWLKVVGKDVLRILDIAFLKGKFYVL
EQLFDQQRRVRVLNPQNPLVLLESTISVPDILLPSPKHMSGVDNGVSPFRNTFNLLPSKS
KGCLYLVLEDFLNEGNTEGGRPRFGSKIMFLVLMMENERKWKEMENIGDEIFFIGLDVAF
ALPSSSQNLPHWKQNSICFAVDQEYYSLDVYTRRTEVPGAECLDYVIYQTYNNCWSLFSL
EEKEKGDVPFDEMPKEEQELYLGLFFPPPAWVKWRCPTLDNVEVRLDGLRFPFQKRKKDG
LSFHEEEQQQEENSDD
>Sgl28570 ULD/UBL/SUMO 108.6 0.1
MSGTTHEEDKKPGDQSAHINLKVKGQDGNEVFFRIKRSTQLKKLMNAYCDRQSVELNSIA
FLFDGRRLRAEQTPEELEMEDGDEIDAMLHQTGGAMI
>Sgl28571 E3_adaptor/Cullin_RING/DCX/DWD 136.2 27.4
MEIYNTKSIIHHINSRELHGFKGRKRPLFSYGTSIDEQNDEPSCSRGVSSSHFNGSTPPL
AVSFAKYCSVNLILEDIRNAHILGVTDEEGYVSLINTRSKLDPSATYEENAAKAIVSSWV
AHDNSVYDICWIKEDTNVLTASADHSIKLWDVEHKKCHGILRGHVGSVKSISCHPTNSDL
VVSGSRDGSFMLWDLRCSPQRGRDWIMQTDQVNGAHTSVKRKRFTRKKAASMTVTPFFNT
KSQTLSSNPPSRRKRPLFSYGISIDEQNDEPSCSRGVSSSHFNGPTPPLAVSFAKTIRNA
HILGVTDEEGYVSLINTRSKLDPSATYEENAAKAIVSSWVAHDNSVYDICWIKEDTNVLT
ASADHSIKLWDVEHKKCHGILRGHVGSVKSISCHPTNSDLVVSGSRDGSFMLWDLRCSPQ
RGRDWIMQTDQVNGAHTSVKRKRFTRKKAASMTVTSVLYLKDDVSIVTAGAVDSVVKLWD
TRNLRAPAAQASPLQETTSEMNGRLHGITSLSQDSNGVLLSASCTDNRIYLYNVLQLEKG
PISSFSGSQIGSFFIKSTISPDASHILSGSADGNAYIWQVDRPHHDPISLTRHEKEVTAV
IGKIATASDDYTVRFWDVQNRNYLLPRATTTRQKRVVKAPRTEYIEEKELSPQRDSPCNL
SDKEAVLQDQDQDQILVQLMKTPETEQDRFRRNLLLQGVSLKDAFNATYESPVWSPSSVL
SPPSSIKKRTIRDYFVVY
>Sgl28598 E3_activity/RING/RING 9.9 7.4
MEVDVGDSPKRKAEIVVPKVDCGGGGEGEGMEVGDGDGDGDGDGEVVKRRKKEVKNGKGD
NIDVDEDEMMMKRVAEIVLVLSAMGRMRAGRDPTVAEKAMMAEARLKVVALCEELTPKDV
VPLDAFGAIMEDLGLNRLKESLGVRHSKISISDKIANSKRRMEEAKAFAAQPVSSTSQRV
QTANGAAVDNRGTPPTVNVLPSDKAGHVPVSTGGFQPPTPVANVSSAASTPMQLHPPGFD
VRPAGHSPVLLNNIGRNSSSVPPPRNDRAHIKPEGRPNGQSMSHIPASSAASQHMSRTTP
VHARPQLPMQANVGTKSLVPDQMPVRAEGNLSLSAPQMTSQPAVAQMSGRAIGQTASGAL
PNVHHPVQGLPFVHGPVVNHHLEVSRLVQKLLTPKHPSRTVWTPPSRDYMNRALQCLYCK
FIINEVENMVVCDACEKGFHLGCLQSHNAKSIRGEWHCPRCLTASNGKQFPPKYGRVTRN
MNVPKVLSNTAGVQLQSDRKVITMSGKVNQPNATINRIQDVKRHSQANQPTNGTQDFKTH
SQAGKVIGSSTESILPRGSDNNAGNNLSVGEKEDRLKSEKCPNSTTGCVVETSSLTSIKP
SNDKTSQQVKTEILSEDLSETEPKPETTSQTNNKFNNLVTSSNDNNSEQKVVVSAEISVR
QQSDSNGIIESRQCKNDEKDVQKNLAEIKRDLDQAEELADASESPSGLHDVEWIGDADSI
MDKKKFYGSCRINGMVYQVQEYALLRSRSGKLIPMKLQAMWEDSQTNSKWLLVHKCYFPD
DLPGEVGRPGAPQSNEVYESTRDSYVLAGYVQGPCEVLPFKKFGEETEKSEQGSLAKDEK
QPIFIRNWFYDDTRQAFCPGAS
>Sgl28621 E3_activity/RING/PHD 34.6 26.3
MATSDDEMEDLPESVTNYYFVDDAEEPISFSVLPINWNTSEAVQGSGKQIYVRGNADAGL
DKIFKPVRAWKFDISGVKPEISVLSKDNNWIKLQKPRQSFEEYIRTVLITVNFLHLVKRN
PDFPGNRIWKKLSEIFGLYDVIPSSKDLRSHRVLIEQAVKQDESLKKSKYLLTVLERNQQ
KRHQAEEDDLVKGKGEFVVNDDELSDEFEEDSGDGVDGSGGEYGSADEEDDDEEPFDSVC
SICDEGGPLLCCDGNCLRSFHATVKAGKPSQCSSLGFTEAEVKAMPYFKCQNCQYKLHQC
YACGQLGSSDKQTGAKVFQCVNATCGFFYHPHCVAKRLIRNNEDSCKALAEKIQAGESFT
CPLHTCIVCKQAEDKTDPDLQMAVCRRCPKAYHKKCLPKEISFGEDEDEDEDMVQRAWEG
LLVDRILIYCLKHEIDDDLGTPARNHIKFPRDVKEKESSARVLKESKIAPKNKPSSLKRS
QAPLVLESKKKNIEDSDPDKKNDRRVPKLQTKVPLEKKSGLTKIGGTSGAEERKCLQQLD
VTKPSQIEKHDESESAGTNKAAVKKFVPQLDSDSERRILDLMKEASSIITLDDIIGKHEK
LIPSRAYKQKMDPCKNITEGKVQNLCVAISDVLKKIDRGSSFEEAKGACGPSDLNQLVKW
KSKLRVYLAPFLYGMRYTSFGRHFTKIDRLKEIADTLHWYVNDDDTIVDFCCGSNDFSLL
MKENLESRGKKCNYKNYDLFPPKNDFCFETRDWMTVQPSELPTGSKLIMGLNPPFGVRAC
KANQFIDKALQFKPKLIILIVPPETERLDKKKKSPYDLVWEYKDKLSGKSFYLPGSVDTN
DKQMEDWNVVTPVLYLWSRPDWTTKHMEIAKKHNHLLDEQRQKHNTSRLSRDLSFKDHGQ
SSIAMKTDDASPQTQLPEGPEEKAVGKCCPSKGKKKKNSKKKRRNEGIHIEDFKRRRFSP
GNPQTEVSYRSPHNSRDGRETGNLRHHVGSPNFEPSPYAERRFSVENRPPRYHKSPSNGD
LIHDQHLPGATGYGTANYDSPYYNDGTVNFHPSEQKIWPMDQGPVADYGPHRNPVDSRMG
YMRPDLHNYGFNHSYSTVEQPYETEAYAIETSCYDRRVNHNPMSAMDKYKLRLDGPSSVR
PGVGGYIPDVPHPPGVVFYDHHQAQAQRQVYPGGPMSFAPGPPNHYYHHHHHTSSGGWID
D
>Sgl28693 E3_adaptor/Cullin_RING/SCF/F-box 14.4 0.0
MWADLPRDILFDIVRYIDMKVDLPRVRGVCRSWRTALNLDELPRRDPHTIEVPNLEGIEI
ECYLRINSSPLFLLESRFYFISPVISSESAGTSNCNRGGWIARMCEAKTETGTGINNRWH
LLNPLRNNGTYYHENIEYLYVEPPITGTINMLDFRVLELARSYSLVNDKDNYNATDLSKK
VVGGWDYTSSYRFAALVQPDFKGHLLLLWRLGDQQWLKVVGKDVLRILDIAFLKGKFYVL
EQLFDQQRRVRVLNPQNPLVLLESTISVPDILLPSPKHMSGVDNGVSPFRNTFNLLPSKS
KGCLYLVLEDFLNEGNTEGGRPRFGSKIMFLVLMMENERKWKEMENIGDEIFFIGLDVAF
ALPSSSQNLPHWKQNSICFAVDQEYYSLDVYTRRTEVPGAECLDYVIYQTYNNCWSLFSL
EEKEKGDVPFDEMPKEEQELYLGLFFPPPAWVKWRCPTLDNVEVRLDGLRFPFQKRKKDG
LSFHEEEQQQEENSDD
>Sgl28745 ULD/UBL/SUMO 108.6 0.1
MSGTTHEEDKKPGDQSAHINLKVKGQDGNEVFFRIKRSTQLKKLMNAYCDRQSVELNSIA
FLFDGRRLRAEQTPEELEMEDGDEIDAMLHQTGGAMI
>Sgl28746 E3_adaptor/Cullin_RING/DCX/DWD 103.7 15.2
MEIYNTKSIIHHINSRELHGFKGRKRPLFSYGISIDEQNDEPSCSRGVSSSHFNGPTPPL
AVSFAKTIRNAHILGVTDEEGYVSLINTRSKLDPSATYEENAAKAIVSSWVAHDNSVYDI
CWIKEDTNVLTASADHSIKLWDVEHKKCHGILRGHVGSVKSISCHPTNSDLVVSGSRDGS
FMLWDLRCSPQRGRDWIMQTDQVNGAHTSVKRKRFTRKKAASMTVTSVLYLKDDVSIVTA
GAVDSVVKLWDTRNLRAPAAQASPLQETTSEMNGRLHGITSLSQDSNGVLLSASCTDNRI
YLYNVLQLEKGPISSFSGSQIGSFFIKSTISPDASHILSGSADGNAYIWQVDRPHHDPIS
LTRHEKEVTAVDWCLHEPGKIATASDDYTVRFWDVQNRNYLLPRATTTRQKRVVKAPRTE
YIEEKELSPQRDSPCNLSDKEAVLQDQDQDQILVQLMKTPETEQDRFRRNLLLQGVSLKD
AFNATYESPVWSPSSVLSPPSSIKKRTIRDYFVVY
>Sgl28781 UBD/Alpha-Helix/UIM 14 0.7
MKLKRRRASEVPPKIRSFINSVTSTPLENIQEPLKCFVWDFDKGDFYHWVDLFNHFDSYF
EKHIKPRKDLRFEDDFLERDPPFPKEDVLQILRVMRIVLENCTNKHFLSCYEHLSSLLAS
SDADVVEVSLQTLATFLKKTIGKYSIRDASLSSRLLAFAQGWGCKEEGLGLTACALNSGC
DSVPYELGSTLHFEFYRVAESSSEYEATGGLQIIHLPHVNSRKESDLELLNTLVKEYGVP
LNLRYSLFTRLRFARSFGSLTSREQYTCIRLYAFMVVVQANTDADDLVSFFNTEPEFTNE
LVSLLSFEHSVSEKIRILSLRSLVALSQDRPRQPTVLAAVTSGGQRGILSSLMQKAIDSV
SNGSSKWSVLFAEALLSLVTVLVSSSSGCSAMREAGFIPTLLPLLKDTDPQHLHLVGTAV
HVLEAFMDYSNPAAALFRDLGGLDDTINRLKVEVSVIENGLQQPSGSSDGSMSTDGTVGN
LGTSSVLDDILPLYSESLLAYHRRLLMKALLRAISLGTYAPGSTDRIYGSEESLLPQCLC
IIFQRAKDFGGGVFSLAATVMSDLIHKDPTCFSVLDAAGLPTAFIDAIMDGVLCSADAIT
CIPQCLDALCLNNTGLQAVKDRNALSCFVKIFTSKGYLRALAGDTPGSLSSGLDELMRHA
TSLRGLGVDMLIEILNTISKLGSADEASASPVESLTCPAPVPMETDLDAKNLSSVESELP
KSEITDPTDLPSDPTLVESYLPDCISNACRLLETILQNSDACRLFIEKRGIETILQMFSL
PLLPVSVSVGQSVSSAFKNFSAQHSASLARAVCSFLKEHLDTTIEVLDSIEGTPVANLES
AKQIKVMRCLSTLEGILSLSNSLLKGTTTVISELGTGDADVLKDIGKIYREILWQISLSC
DSKVEPKQNAEVETENVDAASSSAIGRESDDDTGIPMVRYMNPVSIRSSSQSQWAGERDF
LTVIRSGEGLSRRNRHGLTRIRGGRTGRHLDSFNIDSEVSANVHEPSAALLEHKKKSPDV
LASDILFKLSGTMRSFYTALVKGFSSPNRRRADSGSMSSVAKNIGTALAKIFLEALNFSG
YSSPAGLEMSLSVKCRYLGKVVHDMAALTFDSRRRICYTAMVNNFYVSGAFKELLTTFEA
TSQLLWSLPCPFPTFGVDSGKAGEGSKLEHSSWLLETLQSYCRLVEYFVNSSLLLSPTSP
SQAQLLVQPVAVGLSIGLFPVPRDPEVFVRMLQSQVLDVILPVWNHPMFPQCSASFITSI
LSLVTHIYSGVGDMKRNRSGVTGSSNQRIAPPPDEATIATIVEMGFSRERAEEALRRVES
NSVEMAMDWLCTHAEDPVQEDDELARALALSLGSSTETSKADNSEKSADVIGEEGQMKAP
PVDDILGASMKLFHSGDSLAFPLTDLLATLCNRNKGEDRLKVASYLIQQLKLCSSDMSKD
GSAVSSISHILALLLSEDTDAREIAAQSGIVSVAIDILKNLIGNQLGSDILITKSTSALL
LILDNLLQSRPRISADKAGVASTEPLSDLSVEVAPVEASGPDMEKKLTSDVCEEKWVSSF
QKIFGKSTGYLSMDECHAVLQIACDMLKQQVPAVIMQAVLQLCARLTKTHVLALEYLASG
GMAALFDLPRSCFFPGYDTLASAIIRHLLEDPQTLQTAMELEIRQTLSGGRHAGRIPTRM
FLTSMAPVISRDPVIFTKAAAAVCQVESSAGRTVVVLSKEKEKEKDRSKVSGAEVGLSSE
AVRIPEMKSQDGPGKGSKGHRKIPANLYQVIDPLLDIILQYPCTNSQEDHFSCQAVMDVD
EPSTNVKGKSKIDEANKGDADILPERSAALAKVIFVLKLLSDILLMYAHAIGVVLRRDSE
TCQLRGSSQPDASGQGGVVYHVLNKLLPLSSDKSSGLGDLRTKLSEKASWFLVVLCGRSS
EGRRRVISELVKALSLYSNMGSNSHQSSLLPDRKVLAVVDLVYSVLSKNTSSTSLSMPCY
SPDMARGMIDGGIVPCLSNILQVIDLDHPDAPKIANLILKALESLTRAANASEQSYRSDV
QNKKKSNCSQERPDDQTINASTNDTIHNDVSQISEQETRNVGVVEPNPCEGAGRESNHVT
DMDGSANLDGRPEGEGVPDANPAVELGMDFTGDDLEEGDIMHNNNRISMEFHVENRADED
VGDDDDDMGGDGEEEDEDEDGEDEDEDIAEDGTALMSLADTDVDDHEDAGFGDEFNDEMI
DDEDDDYHENRVVEVRWREALDGFHHLQVGPGSGLIDVPSEPFEGVNVDDLFGLRRTLGI
ERRRQTTRSFERNSTDGGLQHPLLLRPPQSGEAPLLSSGGNVARDSESLSGAGADVSHFY
MFDTPPFLYDFGPGSLFGDRSGGTAPPPLTDYSVGMDSSQLGGRRGPGDGRWADDGQPQA
ANQAPAIAQAVEEVFVSVLRGANVTDTAVGRQSPSMGLPEQQLDAGQNSDHLGLEEDLSH
GQSEEVQLGNGEPEPQQTNSQNTVSAQDHVITHTVTEVSAALERELLASNPVHDSIESAN
GNDPPSDLMRTERDPSLSSVGLEHNILHEGDLGQLHNQQDAQRLARLADVSSGSDFQPNN
DVNNPGVALFNQVEHHPSSCASPDIEMNGADAEPVQTNELQAASESNEPVSDQNISTNGS
SMDADQVGANVEPSRSNAIDPTFLEALPEELRAEVLASQQSQSVQPPTYTPPSVEDIDPE
FLAALPPDIQAEVLAQQRVQRMAQQSEGQPVDMDNASIIATLPADLREEVLLTSSEAVLS
ALPSPLLAEAQMLRDRAMSHYQARSLFGSSHRLTHRRNGLGFDRQSVMDRGVGVSIGRRT
GPSLSNAFKVKEVEGEPLLDGNALKALIRLLRLAQPLGKGLLQRLLLNLCAHSLTRATLV
HHLLEMIKPEAEGIAGSLSMVNPQRLYGCPTNVVYGQSQLLDGLPPLVLRRVLEILNYLA
TNHSAVANILFYCEPSPLPESSQKFAETKKGKEKVGENEVPPNSLMESEEGSIPIILLLK
LLNRPLFQRSIAHVEQVMSLLQVVVYTAVSRLESPSLPEQVTDDPQALSVKASDEIQRDV
TLLETETSNQVKKVETEKPSISERKEGHKIFDVFTQLPRSDLRNLSRILGCEGLSDKVYM
LSGEVVKKLASVTASHREFFIQELSVLAQDLSSDAVEELATLHNTKMMGLGVGAMAGATI
LRVLQALSSLVSQGVDNAVCQGSNDEEEQAILLKLNSALEPLWLELSYCISTTESELGQS
TLSPTMASINAGDGAAGSSISSPPLPPGTQRLLPFIESFFVLCEKLQSSNSFLQQEQTNV
TAQEVKESADSSSSVPTKCGGDSQRRSDSAFLFSKFADKHRRLLNAFIRQNPGLLEKSLS
MMLKAPRLIDFDNKRAYFRSRIRQQHEQHLAGPLRISVRRAYVLEDSYNQLRMRSNQDLK
GRLNVQFQGEEGIDAGGLTREWYQLLSRVIFDKGALLFTTVGNNATFQPNPNSVYQTEHL
SYFKFVGRVVAKALFDGQLLDVYFTRSFYKHILGVKVTYHDIEAVDPDYYKNLKWLLEND
VNDILGLTFSMDADEEKLILYEKTQVTDYELKPGGRNIRVTEETKHEYVDLVADHILTNA
IRPQINSFLEGFNELVPRELISIFNDKELELLISGLPEIDLDDLKANTEYTGYTVASNVI
QWFWEVASNFSKEDMARFLQFVTGTSKVPLEGFKALQGISGPQRFQIHKAYGAPERLPSA
HTCFNQLDLPEYSTKEQLRERLLLAIHEASEGFGFG
>Sgl28794 E3_activity/RING/RING 25.3 13.9
MSLGSAEKGASDDQISSLHCWKYKLVEGNNIDPGNSSPAKDNPECCICLTKYKDKEEIRQ
MPCSHIFHKICVDQWLKIISCCPLCKQGLHV
>Sgl28802 E3_activity/RING/RING 23.5 13.9
MGFLNHVQISSSRFVHGETRAVEEEEELGEDAPRILTSDQIRPTREIPASILVRTAMRVS
RSKWFTFLRRVFHYQNGSRSHLGANPFNSCSWMMLELLALLVQICVTMITLFVSKAEKPV
WPMKIWVVGYDFGCVTSLFILYWRYRHYHLRQQRDNNGISFPDLEQQSSINEESSRELHL
VNKCKASLDLFFAMWFVMGNVWTFDSRFGSFSRAPKLNSLCITILAWNALTYSFPFILFL
LLCICVPLLSSFIGYDMSLGSAEKGASDDQISSLHCWKYKLVEGNNIDPGNSSPAKDNPE
CCICLTKYKDKEEIRQMPCSHIFHKICVDQWLKIISCCPLCKQGLHV
>Sgl28830 E3_adaptor/Cullin_RING/BCR/BTB 56.1 0.0
MKSSAYHVHTTSRLAQWRIHNLSSCTFRRSDPFPLGLWNWHLALEKNKVLMLKLYPEISN
YTRDNPPIASFVIRVLFSDSDSDATTHPNRYPLVIVHPEISDQLLKTNHDFVWPIDVPVP
LTGKLIIDLQFLDLKTSSPQGGEPCSIWAAEGSTSIRRSNSAALTSLRRMLMDGIYTDIT
INTSNGRVGAHRAVLAARSPVFQTMFSHNLQEKELSTINISDMTIESCQALLDYLYGCVQ
HNDFLHHRLSLLRAADKYGITDLKEACHVSLLEDIDANNVLERLQNAALYQLPQLKSSCM
RYLVLFGKIFDLRDDFNVFLQCADRELIADIFQEILATWKGF
>Sgl28831 ULD/UDP/UBQ/UBQ_PIM 65.5 0.9
MKITVMTGDEQIISLDVDRDEAVENVKALLEVESGVTLQQQQLLYNGKEMNNHEKLSALG
VCDGDLIMMMHSSDGSSNNANNLALNPDGSAVNPAAFQNQLLSDSTLMAQLFQSDPELAQ
TLSGNDLNSLQEILRQRHRQRAQMKQKENEELALHYADPFDVEAQRKIEASIRQKGIDEN
WAAALEHNPEAFARVVMLYVDMEVNGVPIKAFVDSGAQSTIISKSCAERCGLLRLLDERY
KGIAHGVGQTEILGRIHVAPIKIGNMFYPSSFTVLDSDNMEFLFGLDMLRKHQCIIDLKD
NVLRVGGGEISVPFLPEKDIPPRFLDEERFSKQASGSGAQVSSGSKGTRDATGSHSSGGA
GGNPGQGSDFEAKVAKLVELGFQRNDVIQALKLFNGDEEQAAGFLFGG
>Sgl28833 E3_adaptor/Cullin_RING/DCX/DWD 41.9 0.0
MASTGNPNQNQNQQQQQQQQQQGVGVGGQFDMNKFFKPTNITSPTHTQAQNPNNINMNMN
IGATAAAASYPPPTTGSAPYSYPPQNPGPPYYHHMPPFPPPQDHIHHQRSVSFPTPPLQP
APQNSNPGARLMAMLSTPPPDFNYSHQNPTPVPVPVPLPSAPLPSSSSDFSTVPSLHPQP
TPIRMPSSKLPRGRHLLRDHMQYDIDVRFQGEEQPQLEVTPITKYVSDPALILGHQIAVN
KTYICYGLKMGNIRVLNINTALRSLLRGHTQRVTDMAFFAEDVHLLASASIEGRVYVWKI
SEGPDEEEKPQISGNVVLAIHFTGDEGSVHPRVCWHCHKQEILVVAIGKSVLKIDTTKVR
KGVEFSAEEPLVCPLDKLIDGVQLVGKHDGEVTDLSMCQWMTTRLVSASKDGTIMIWEDR
KAIPLLVLRPHDGLPVDAAKFLAAPHRPDHIMLITAGPLNREMKLWASSDEEGWLLPSDA
ESWRCIQTLELKSSAEPRNEEAFFNQVVALSQGGLLLLANAKKNAIYAIHLEYGANPAAT
RMDYLAEFTVTMPILSFTGTSDVLPHGENLVQVYCVQTQAIQQYALDLSQCLPPPLENLG
IEKSEATITRDAAECVPPLEPSGSKSFEAPFSAAKPSNSSGLASSSDIKNPVSTASDTIL
VQESSTSNVDPNPTSLLSASSNANLAPVTSPSLPLSPRLSKKLSDLRGDQAVTDYPIDRQ
IDTTQTSSSALAASNDDNLTVQGTSDIVNPPVMFKHPTHLVTPFEIMATSSADATRVSEK
GENEAKVQDVAVSNETENVEVEVKVVGEAGLANSDECTRSVDPQIMTDRKEKSFFSQASD
LGADMTRECCALPSETSITEEARNSIMEALAQPSNSGEEEGDEANNDVSVKGADFAAPVA
VPQSPTPGAKGKRQKGKNSQASGSLSPSPSVSNSAEMLQGTVGGSTVPFMEPSTSQMLAM
HETLNQILTMQKEMQKQMSTVVSTPVTKEGRRLESAIGRSMEKASKANTDALWARIQEEI
TKLDKSVRDRMQQIPGLISNIVNKDLAAVFEKTLKKELTAVGTSVARTISPAIEKTISSS
IADSFQRGVGDKAVNQLEKSVTSKLEATVARQIQVQFQTSGKQALQDGLRSCLEASIIPA
FEMSCKAMFEQVDSAFQKGMAEHTTAAQHQMESSNSQLAHTLRDALNSASSLTQTLSGEL
ADNQRKLIALAAAGTNSKAGNSLVPQLSNGPLASLHEKVEQPFDLTKELSRLVSEHKYEE
AFTAALQRSDVFIVSWLCSQVDLQRLLSTIPLPLSQGVLLSLLQQLSCDITKDTSRKLAW
MTDVAACIIPHDPVIAVHVRPILEQVYQILNHQRNLPTTSAAELSSIRVVMHVINSMLLT
CK
>Sgl28913 E3_adaptor/Cullin_RING/DCX/DWD 81.7 14.3
MAKIAVGCEPVVGCLTAPKKKDYKVTNRLQEGKRPIYAVVFNFIDSRFYNVFATVGGNRV
TVYRCLEGGTIAVLQSYIDEDKEESFYTVSWACDIESNPLLVAGGSNGVIRVIDASNEKI
HKSFVGHGDSINEIKTQSLKPSLIVSACKDESVRLWNVHTGICILIFSGAGGHRNEVLSV
DFHPSDIYRIASCGMDNTIKIWSMKEFWTYVEKSFTWTDLPSKFPTKFVQFPIFIASVHT
NYVDCTRWLGDFVLSKSVDSEIVLWEPIIKEHSPGEGSVDILQKYPVPDCDIWFIKFSCD
FHYKAAAAGNREGRIYVWELQSCPPVLITKLSHPYSKSPIRQTAMSFDGSTILACCEDGT
IWRWDVVS
>Sgl28926 ULD/UDP/UBQ/UBQ_PIM 634 30.6
MQIFVKTLTGKTITLEVESSDTIDNVKTKIQDKEGIPPDQQRLIFAGKQLEDGRTLADYN
IQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVESSDTIDNVKAKIQDKEGIPPDQQRLI
FAGKQLEDGRTLADYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVESSDTIDNVKA
KIQDKEGIPPDQQRLIFAGKQLEDGRTLADYNIQKESTLHLVLRLRGGMQIFVKTLTGKT
ITLEVESSDTIDNVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLADYNIQKESTLHLVLR
LRGGMQIFVKTLTGKTITLEVESSDTIDNVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTL
ADYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVESSDTIDNVKAKIQDKEGIPPDQ
QRLIFAGKQLEDGRTLADYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVESSDTID
NVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLADYNIQKESTLHLVLRLRGGL
>Sgl28964 UBD/UBC-like/UBD_UBC 156.4 0.0
MNSGGGGGGVGGTGTGSSGGGRMSASRSSWRSTSVSGSGKRIQKELKDLDSHPPPLSSAG
PIADNLYHWLATFIGPPGTPYEGGIFFLHILFPVDYPFKPPKVVFKTRIYHCNVDSSGNL
NLDILKDAWSPALTISKLLLAIKSIFLTPLLNPYYVVPSIAHLYHVDRKTHDQLAAQWTH
RFAK
>Sgl29035 E3_activity/RING/PHD 40.2 5.6
MAESPIKAKKRLDLKSPTKPSNSPISFLPPQTPNTDFNSSPIESTPLRRSSRRLSQNAND
FKLTPEKSVKQSLIKTLEKSPKTPKSSKRSKLSSTHNQKVLNEDPIHPKSPALTEERKRK
RGNELGDAAKTRAQVRARAQNVPKKRVYYKKVVYDKAEFAVGDDVYVKRRENASSDDEDP
EVEECRVCFRAGETVMIECDDCLGGFHLECLKPPLKEVPEDDWTCEFCEAKKLGKKVQLP
VPPKGMKRARTLKEKLLSSDLWAARIESIWKEVDKTYWFRAHWYMIPEETEAGRQPHNLR
RELYRTNDYADVEMESVFRHCYVMSPKEFAKAGNAGDDVFFCEYEYDIRWHSFKRLAEIN
DVEEDDDNDDDDSASDEDWKSTKDPESESEEDMDFEDENDKRKSFGPPSQELAANSRKGH
IFGLQKIATLPKSLPCRDKEMEEITTIIKDAISDDQCLGRCMYIHGVPGTGKTMSVLSVM
RSLKSELDSGNIKPYSFIEINGLKLATAENIYRVIYEALSGHRVGWKKALHFLNERFSEG
KQVGKGKNKPCILLIDELDLLVTRNQSVLYNILDWPTKPNSKLIVIGIANTMDLPEKLLP
RISSRMGIHRLCFGPYTYQQLQEIIMSRLKGIDAFDKQAIEFASRKVAAISGDARRALEI
CRRAAEIADYRIKSHISLANPPSVGKTHVVMADVEAAIQEMFQAPHIQVIRSSSKMAKIF
LAGMVRELYTTGMAETTFEQLAVVVSCFCTSNGEQFPGFDTLLKVGCKLGECRIIICEPG
YRHRLQKLQLNFPSDDIAFALKGCPELPWLAKYL
>Sgl29046 E3_activity/RING/RING 28 6.6
MHLCYGVADVTIHGQLIYASEFVDITESLYRIAQMSWNQHMDSHYHYVGSNAPYNSAGSF
MDFFAGLTYDHVNFIFSGSQIQDCSYSPISPGYYKFGYPDPGATQYYSNSPAYEVYDHIV
SGIDDYTRRPSDFPSSDQTAAANHQSQRMSNTSNRDCPRSRHSSQDYQTIWQDNIDPDNM
TYEELLELGETVGTHSRGLSPQQIALLPVTKYKCCFLLRKTYRSERCVICQMEYKRRERL
ITLPCKHKYHLGCGTKWLSINKACPICYTEVFADANKKSKVVSYTIAIDIWAHDT
>Sgl29079 E3_adaptor/Cullin_RING/DCX/DWD 24.6 2.4
MDRYVVPTEPLSSNPNPIRRHRWKRTAIELDGCIESKYKRELSGLLVQSYAEIGVFSHLY
HIDGRPCSTHRNRVMSFAGLDHQGSFRRHGVSALEFDNQVACTSLKSSEIHIFDIGYVSS
DPVEVLRKKPSVTINGSNIVTGLSDVAFTSSDDSRVFASDTSGSINIWDRRQGVFPCLEL
TTNSQNALNSIQLNVENQIVFGAGKQGMIYMWDLRGGRTAAAFQSHKEAYHPPMTSVKVS
SLLEKIESLKAQSDVVPKDIHSINLDPSSLFRLAFHLDDGWSAILDIHSLEVTHIHCPPP
AWLTGSEMSNLSYLTKPTWLSTNSIYAVGSSSDKGLHLLDFYPDSSSPCHVEFSEDMVNT
SRRNRFVPLSEDVSACAAHPLNGFIVAGTKQGSLLMIGQRKKAVRGDDGF
>Sgl29108 E3_adaptor/Cullin_RING/SCF/F-box 12.6 0.2
MIFFLVTGISFFFFLNSLSLKPLPPWANDVRLLPLCFWKELSFSPICKGFKKGVFGDFWG
LPSIMAMKQGSSSSKFENSQESGQLSVLDLPELALDCILEKLPPSGLCSMAAVCSSLKER
CISDHLWKTHMEHKWGKVLGPAASREWQWFIACKRNSSASVGKKSQSFIKFIWNVWPLTW
FTSKYDKTNNINKDSTSPSPSPMVDSVMSWYLALESGKFWFPAQVYNRENGHVGFMLSCY
DAELSYDPQSDTFQARYPPHGRRAVAIESGIQWERLRAAPVDTPPHDLHPSDCLNDLHPG
DHIEIQWRRNKEFPYGWWYGVVGHLESCDGNENYCRCHSSDTVLLEFNQYTPGSRWRRTI
VSRKDHREEGNESDGFYGGIRKLHKRDEIATWKSLWPKEILD
>Sgl29167 UBD/Alpha-Helix/UBA 16.6 0.4
MDGQGVRGGSSVDSFLQNYNLGKTLGIGSFGKVKIAEHKLTGHKVAIKILNRRKIKNMEM
EEKVRREIKILRLFMHPHIIRLYEVIETPSDIYVVMEYVKSGELFDYIVEKGRLQEDEAR
MFFQQIISGVEYCHRNMVVHRDLKPENLLLDSHHNVKIADFGLSNIMRDGHFLKTSCGSP
NYAAPEVISGKLYAGPEVDVWSCGVILYALLCGTLPFDDENIPNLFKKIKGGIYTLPSHL
SPGARDLIPRMLVVDPMKRITIPEIRQHTWFQAHLPRYLAVPPPDTMQQAKKIDEEILQE
VVRMGFDRIQLIESLRNRLQNEGTVAYYLLFDNRFRASSGYLGAEFQETLDNKYSRMHPN
EPASPAAGHQYHGYVDYQGIGLRPQFPVERKWALGLQSRAHPREIMTEVLKALQELNVVW
KKIGHYNMKCRWLPGIPGHHEGMVNNPVHNYLGEESSIIENDGVLRSPNVVKFEVQLYKT
REEKYLLDLQRVQGPQMLFLDLCAAFLAQLRVL
>Sgl29170 E3_adaptor/Cullin_RING/DCX/DWD 102.2 11.5
MSTLEIEARDVIKIVLQFCKENSLNQTFQTLQNECQVSLNTVDSHETFIADINSGRWDAV
LPQVSQLKVSRKKLEDLYEQIVLEMIELRELDTARAILRQTQVMGVMKQEQPERYLRLEH
LLVRTYFDPHEAYQDSTKEKRRAQIAQALSTEVSVVPPSRLMALIGQALKWQQHQGLLPP
GTQFDLFRGTAAMKQDVEDMYPTTLMHTIKFGKKSHPECARFSPDGQFLVSCSVDGFIEV
WDHISGKLKKDLQYQADETFMMHEEAVLCADFSRDSEMLASGSTDGKIKVWRVRTGQCLR
RLERAHSMGVTSLCFSRDGSQILSTSFDSTARVHGLKSGKLLKEFRGHNSYANHAMFTHD
GSRVITASSDCTVKVWDVKTTECLQTFKPPPPLRGGDASVNSVHLFPKNMDHIVVCNKTS
SIYIMTLQGQVVKSFSSGKREGGDFAAASVSPKGEWIYCVGEDRNLYCFSVQSGKLEHLM
KVHDKDVIGVTHHPHINLVATYGEDCSMKLWKP
>Sgl29210 E3_activity/RING/PHD 35.7 18.1
MNARKLLLREEVEVRQLEEGLKGSWHSGVVVGVSDSCREVKYDELLCESGKSMLIESIPV
TGAIEGLYQRPCVKFNYRGRIRPIPPLAQPSAAETHLAFGVCVDVWYNEAWWEGVIFDCN
EDAKERRVFFPDELDERVYKLNDLRVTWEWDEFTGQWRERGVWMLVNLAKEHKKSGYLFH
FIRRVWSCLKVHYGFKKMISEWTCGAYCVWKEYFREVIYEMTTKPVGKGLAFPTQVHAAK
KRKRRSKRAQVRFLNASVLTRSMQKTVEKEIRLAVRTRRMCMSEAEDSLIAASKKNSHFT
DSYFQQSRSVTADACINTDIDVSRSDDNTEREQVPRQCCDQIGAKVVDDGCCHSRMPQND
SLPSMDSRMPENCIKTSNNRLRRKWQLAEANLPPKKLMASPLCENNLDINRSHGFRITRQ
MQGRVPLQFQDNDPVYKSRELLLLKQKKVGVAMRYPVHRKGKRIRICRRSIGKKRSPKRR
IKKILPRKTQEATIKASKPMLQRELKESESQQKVGDSFAGHCDEIQPVTTSLQEDETQDP
VETAPKQKGKRSRCRDSVCLVCQYGGELLHCDRCMSSYHLACLDVKEFPVGESFCPSCEC
GLCGLEHSSSDDQLFTQVCYQCSRRYHVACLNEVEAKVSEDSFSDKFCSRSCFKICARLH
ELLQISNPTTMEGLTWTITRSRRNDCNVHNERVHPLIQVSQVLNVFHECFEPIAEPHTGR
DLVADIVYNSGSKFRRLDFHGFYVIALVDGEEVVCVATIRIHGQKVAEMPLVATRFKYRR
KGMCRILVDELEKMLVEMGVERLVLPAIAQLSDTWVSSFGFADMPAPLRRELLGYPFVLF
QGTTMFQKILRRPAPPDSLLAGPELAQGKHTERDCNRRFSLQYKRRGKSEASGKKKTVMD
GSDRNQSSYKLVYKRRRIQASRDSIDIQ
>Sgl29227 E3_adaptor/Cullin_RING/SCF/SKP1 100.4 0.2
MASSSSTPKKITLKSSDGELYDVDEIVALESQTLKHIIEDDCGDTAIPLPNVTSKILGKV
IEYCKKHVNSRSISSDDVKDAEELKKWDNEFVKVDQETLFDIILAANYLDIKSLLDLTCQ
TVAEMMKGKSPEEIRKTFHIVNDYSPEEEAEVRRENAWAFE
>Sgl29242 E3_activity/RING/RING 29.1 16.2
MKVNILQWHAVASWTWDAQDETCGICRMAFDGCCPDCKLPGDDCPLIWGQCNHAFHLHCI
LKWVNSQTSQAHCPMCRREWHFKD
>Sgl29409 E3_adaptor/Cullin_RING/SCF/F-box 20.4 0.0
MKKVKAATGNKYFSLLPTELCSEILSWLPVTSVGRCKCVCKSWRDMINDPNFNKLHFGRR
SVETHYYSNTTRLIMFTPYRKPPLKRISSFNVNDYKLSNFTQLYYPTQLPTTLLYLIGCC
NGLICFSSYHKTCDHRFFLYNPITGAYKHVPSTSTSTLISKDLWINSFGYDHISDDFKIL
LISHTEIVKYTTLLYSLKLNAWEVIENPPSSWEVDEFSKSNTPILINNSFHWLGLTTSLS
SARVFKTIKGFEISSRRYFEMQLPKGVYTNLPKLTVLQGQLCVVTCCLDIWILKEYGDHK
SWTQILFGKVYDGLLNNFDVLQDWGRYKCISCFQNGPNNIILVITRMAPDFSTTQLEHYL
ICCNYESRTLEKIDISDCLKHDSCDSNLPIHAIQPWVDSLVDPDALSSLS
>Sgl29436 E3_activity/RBR 147.9 26.1
MDSEDDMHDANDVESVEDFYSGDTAIDSDDAADGDYEFIDNDSEEDYDDFTSHRNQQNYT
ILSEADIRQWQEDDILKISTVLSISKVEASILLRHYNWSVSKVNDEWFADEEKVRKTVGL
LDRPVVEFPNTREMTCGICFEAFPSAMMSAAMCGHPFCNSCWSGYLGTSINDGPGCLMLR
CPDPSCGAAVGQDMINKLACEEDKRKYARYFLRSYIEDNRKAKWCPAPGCDYAVDFVVGS
GNYDVNCRCSHGFCWNCTEEAHRPVDCGTVCKWIMKNSAESENMNWILANSKPCPKCKRP
IEKNQGCMHITCTPPCKFEFCWLCLGAWSEHGERTGGFYACNRYETAKQEGVYDECEKRR
EMAKNSLERYTHYYERWASNQSSRQKALQDLQQMQNVHLEKLSDIQCQPESQLKFIIEAW
LQIVECRRVLKWTYAYGYYLPEHEHARRQFFEYLQGEAEAGLERLHQCAEKELQVYLNAE
GPSKEFNEFRTKLAGLTSVTRNYFENLVRALENGLADVDTHGACSRTATSKSLGGSKSRN
GRGKGASAKSSSSTRNIDDSSHWSCEHCTFANVRSATICQMCHNRR
>Sgl29451 E3_adaptor/Cullin_RING/DCX/DWD 181.7 22.4
MSSSTLDPSHSFKPYTLKQTLTPHKRAISSVKFSSDGHLLATCSADKSAAVFSLSTTTSS
DDSPFSNLQHFTGHDQGISDTAFSSDSRLLATASDDKTIKLWDITTGQCIKTLLGHTNYV
FCLTFNPQSNMLVSGSYDETVRVWDVKSGKCLRVLPAHSDPITAVDVNREGSMIVSSSYD
GLCRVWDVSTGHCTKTLIDDENPPVSFVKFSPNGKFILVGTLDNTLRLWNFQTGKFLKTY
SGHVNSKYCVSAGFSITNGKYIVSGSEDNCVYMWELQSRKVVQKLEGHTDTVISVCCHPT
ENMIASGALGNDKSVKIWTQGKA
>Sgl29456 E3_adaptor/Cullin_RING/SCF/F-box 14.2 0.0
MSSSISTDYYLSLELWEDISARLPIKTLLRMRSVCKAWRSMIDSPSFTDMHYRIYNESNP
SKAKLLLCAAESQNLYRYGSCKFTTRHSTTFRKVDEVCEISNLSKEIILLGSCNGLWLIE
HDDGDDYRSVGRVAIRRVLNPFVRKSFRLPDDQIGLFTVNCVLGFAPSTNDYKVVRFMQD
IRTSDFSISVCSLSGEGDHKWRTKSDKISVPIWNLSKRLRATDVLFIKNAGYWLNENASL
LMWFDFDREELSFSALPDAAEDTQTLPSKFIFNFLDSIAVLSISYSSTRVWTFDKNSSSS
SGGGGNNKDHHPWRLWLSTDTHPNAVKFLANFQILPKAILYQHATSTFFMPVRCPASRKL
VSYNVSNHKVRYLSKQGFWSSVDNYVENLVSHNHPQWKRCDIFSPKKAKLVHSPLPYPYP
FPFLFPTELISRAFRRKRRVL
>Sgl29457 E3_adaptor/Cullin_RING/DCX/DWD 25.4 24.3
MEDHFEEEDNDLDLFPSTSSYPRTPKIFDRFGSSSSSDEDISPSSTSSAIHQNPNSTTNS
SNGVVKAAGKKLDYMIQFLDRKLSKVGSANSSSNGGSGAQNFPLPEFVGSGGGTGIFRLP
IRSAVRPDRPPCVEVRPRPRRETQVGRGLRTMASTDKQLWCGGENSVRCWELSDIFSCND
EDDDGNGGDCGCEVGNCVCMSEAKRSGDEMTARFKESIEVVSEVVCMVEDEGERVIWSGH
KDGSIRCWRMDDAKKNGFKECLSWQAHRGPVLSMVMTSYGDLWSGSENGVIRIWSWEAIV
KSLSLKAEERHMASLDVERSYIDLKSQVTINGVCYMFVSDVKYLLSNHSTAKVWSAGVLS
TALWDARTRELLKVFNTDGQVETWGDASSFQDLTTEDEMKSRYVVSLKKEKPQASFGFFQ
RSRNAILGAADAVRRATVKGPVGDENRRTEAMVSTIDGMVWTGSSSGLLVQWDGNGNRLQ
EFQYHSYAVLCLCTYGNRIWVGYSSGMVQVVDLQGKLIGSWVAHSSPVIKVVVGSAYMFT
LAGHGGIRAWNITSPGPIDNLIRAELSGKEFLYTRQEKLKILSGTWNVAQGRASYDSLIS
WLGCASSDTDVVVVGFQELEMGAGVLAMSAAKETVGLEGSAVGQWWLDTIGGILDEGSTY
ERVGSRQLAGLLIAVWVRKSLEVHVGDVDAAAVPCGFGRAIGNKGAVGLRMRIYGRIMCF
VNCHFAAHLEAVNRRNADFDHVYRSMVFSRPSNFNVAAVGASSTVQMLRGANGVGCRSVE
VLPDLSEADLVIFLGDFNYRLDGISYDEARDFISQRCFDWLRERDQLRVEMEAGRVFQGM
REAILRFPPTYKFERHQPGLAGYDASEKKRIPAWCDRILYRDSRSSSASECSLDCPVVCS
SLEYEACMDVTDSDHKPVRCKFNVDIARVDESVRRQEYCEIVESNPKVRSLLQELCRVPE
IVVSTNNIILQDEGTSLLRITSKSTSDRAMFTIVCLGESNINEDGLASNHSPRGAYGFPR
WLQVTPAKGIIEPDRTLEIEVHHEEFQTLEEFVDGVPVNSWCEDARDNEVIMVVRVHGSC
CTKIGNYRIRVRHCCLTKKKSSKSKQENERKVQSNLLHRSSIQNLNTSLDVFDKLHKLHT
P
>Sgl29481 E3_activity/RING/RING 34.5 18.3
MSSGGHTHWCYQCRQPIRLRNRGMVCPYCDGGFVQELEELSGGPVGGITPHGLRDGPDQL
YGIMEALDSLMLRSNPEHRLGLIEALDAFMGQRRRHGIDAERSPWLIFQGQVPGRVPMPR
NGGFEMFFNGNPGVGFSRGNNGDVFVGPGLQDLIEQLMVDRQGPPPAPRTAIDALPIIKI
TRAHIQADSHCPVCKDEFELGAEARQMPCNHVYHSDCIVPWLVQHNSCPVCRHELGSSTS
SCRQNPNSSSRRSATSSSSRERGSSEQNTSRRNPFSFLWPFRSNNSSSREYVPSSANNPP
PTRGENHEMNYSGWPFDY
>Sgl29485 UBD/Alpha-Helix/UBA 24.8 0.2
MSSVSKSKSKDKKAVKEQKTPSKSSAPPNGGSGLPASAYNPLLGTFHTIEPSSTAPTLHV
NGRFRNIDDSDDHSGSTHGSGGDYDSASNNDSRSVESEEHNKDKLNGPLKQEVVPGADND
KREKIRQKNERKHQRQKERRAQELHERCSGYLMSRKLEALAQQLVAMGFSHERATMALIF
NEGRVEEAVAWLFEGGEDADKHKEQNLDTGSNLKIDISDELARIAELESKYKCSKQDVER
AIVTCEGDLEKAEDNLRSLKQDQFAVLPKSDETGDPPTLSNGRVSIAPSLSNVRLLQSKP
NAATLIPQRRDQKDFNYTKAAVTGGLASKLVPKTVQPVQRVQPKLEWPRPQQINTPADKR
WPVGAGSSPSVSYSLAPPLQVSPPPSKAELRYATVGNDYKNLQPGSVREPVVMMQRPQSV
NVKPAPATSISSSPPGSVAGWYPTSSEILKPNGLLPHIPSTRSLSPNNLTSNQFYHPAQY
QQQQQQQQHQQQHQHHHQHQHQHQPYMPGSSPMDNPGNARGSTSWSRMGGSSTIAPASSL
GLFSGLGSNCSSGSNSPVDWNTSGSMPSCDYTNIDWSLDRSFLPSKQNGLWMGVAPYSRS
SGSHIYDSGASAMGIPIPMRPSSSSSGNGVPIVGLQEGGAGMADTSGSSSREWTSPFEGK
DLFSLPRQFVSSPSL
>Sgl29495 E3_adaptor/Cullin_RING/SCF/F-box 18.9 0.0
MAIGREKDNCNSRHFSLLMKSCCPNPTDPSHSVIPFPPNTNNHKTPKKVISSFSKTSISS
LPDDLLYEILTRVPLSSLPSISAVCRRWAHLLHSPSFSLLRRNHRLIHPTIFAFSPSSTS
TLRVFLDDAWKMPACENDVVFGGSLQFQLHTEFSHARVVGIGRKAYVVTREGTLVYDPWT
GVVKPRAGPLFSRKRFAAASICGRIYVAGGSLRASAIEEYDPHADEWRVVAHAPRRRYGC
IGIGVDGVFYIVGGLMIGGASESRAAEARVCASSMDLYDVAGRGWLRSRAVPGGGCVVAA
CGAEGCVYVLASHAVELSFWRFNGRRKGEGGGGVFGEWCRMRSPPLPAQIRLDGTVRFSC
VGVEDKVVLIQVMGSIDDLLRRSGRNVRGYKEGLVLIFDCVTEEWTRGPDLPELVQRAAC
VCVEC
>Sgl29513 E3_adaptor/Cullin_RING/SCF/F-box 19.4 0.0
MADHNKFHNIQSNEDLLVEILARLPVKSLIRFTCVCRYWQSLITSPSFSKTHYATRLRLL
RNRTQGDDDHDSLLSTFTNGCSISIFSYEDLSYKTAFKFRPYVHVPKPLRFGVCHCHVIS
DCKISGPCNGLFLVTLSKGLHELVLLIWNPATRRAFKVPYVEGIGHCNGFGFDSNSNDFK
VVSFNGTRNKGGVVLVYSLTANAWRQVDAGFRFGNFDMSMGGDTCTTNNGGMHHWTICDV
RYLREYLVSFDMVHEVFVETPMPSSYLSLMKKGSNHMYPLVYESDNRNNPTGINIWMVKE
YGRTGSWVKLQYIALPREVMGFGSSLLMWRNNEGIIYVSYTEGQGGLCCFNLTTKEVKVL
GVPSELWSFIGYTESLFSVTNFAQHQQPPFVYQNEAECSTLGTEDHVDAAADDDDGDDDD
SSTDSAFITPEGALNSPYDEIYVDCDEDAESCLRKENECQRLSKLPYCFREVNQPISYNT
CLF
>Sgl29591 E3_activity/RING/RING 19.1 10.2
MRTSGGAVSKRSVSGNRHVRVKGMESEDSDEDYVAELEEVDDQSDELNSLVGDASEEDSC
FEAGEEEEEEEEEVGWRRVVKTRARKEEEEDEGGWRRVVKTRAMKESTVRRKNGMKMPNR
KRRVKSDDDEDSDDDDEEFTPEEEYLEEEEEEEDEEEEEEEEEYCLRETTSRKRGRRTAL
KKNDSAKSQRKRSVKAARKASTKKRKKPSILRRQAKSDGDEDFVGKGPSLRGRNRKKTLR
RKKRMTAGSESEFCSDSSDYEFTISEEEREQIREANMICGSLRPNLRSSRRIQEDEIFYE
PKKAPPRKGKEKAEVKKNDVVKPVCGICLTEEGKSTVRGTLNCCTHYFCFACIFEWSKVE
TRCPLCKQRFVSISKPARCGRGFDLRDTVIPVPERDQVYQPSEEELRDFLNPYENVICTE
CHHGGDDALMLLCDLCDSPAHTYCVGLGREVPAGNWYCDGCRPAAVMSSQSQTPDITLDQ
RSSTGFSDGTSTYENMAEIDLNVTIPETPISQGVLSSPRFSGGSLQAPSPASGLGVSTVS
GRRMIHEQIRHILSNRLSQLSPGADISALRNRINRGVNSTQQLSRTTDVGPSHHAQYVDS
LQENPSISVQNRNSFPGRMGRMVRQVGQPSTSANSSFHSQTHWTGLDGIDLGEGQNQISA
GEHLRPCTGRPSMGHEIATSPSHNRFEENASFVKQQVHTMVRSQLKSLSRDMNLGHNDYV
EILRRSAHTIMATYGLEPRRHDTYNAQPPICLHFNSRLANVEASPINGCCLACFEAFAKD
VVKMILDIVMQPPHWFGFNINT
>Sgl29605 E3_adaptor/Cullin_RING/DCX/DWD 95.1 3.0
MSSLSRELVFLILQFLEEEKFKESVHRLEQESGFFFNMKYFEEKVQAGEWEEVEKYLSGF
TKVDDNRYSMKIFFEIRKQKYLEALDRQEKSKAVEILVGDLKVFSTFNEELYKEITQLLT
LTNFRENEQLSKYGDTKTARSIMLVELKKLIEANPLFRDKLVFPTLRSSRLRTLINQSLN
WQHQLCKNPRPNPDIKTLFTDHTCNPPNGAVAPAPVTLPVAAVAKPTAYPQLGAHGPFQP
TAAAANANALAGWMANAAASSSVQAAVVTASSIPVPQNQVPIIKRPRSPPATLGMVDYQT
PDHEQLMKRLRPAQSVDEVTYPTSRHQPSWSLDDLPRNVAFTLHQGSPVTSMDFHPTHST
LLLVGSSNAEITLWEVGSREKLASKPFKTWDMSSCSLQFQTALVKDVISINRVAWSPDGN
YLGAAFTKHLIHLYAYSGSNDLRQHLEIDAHVGGVNDLAFAYPNKQLCILTCGDDKLIKV
WDLTGRKLFNLEGHEAPVYSIRPHHKETIQFIFSTAFDGKIKAWLYDNTGSKVDYDAPGN
WCTTMLYSADGTRLFSCGTSKEGESYLVEWNESEGAIKRTYTGFRRKSNGVVQFDTTQNH
FLAVGEDHQIKFWDMDNVNLLTQTDAEGGLSSLPRLKFNKEGNLLAVSTAADGIKILATA
TGLRLLRTVEAPPFEGLRTPIEAAAIKNGSMEKPRLVEDATETKIKPWQLAEIVEPAQCR
FVTLPESMDSFSKKLWKWSRSEQNPNGKATASVIPQHWQPNSGLLMSNDVSGVNLEDAVP
CIALSKNDSYVMSAAGGKVSLFNMMTFKVMTTFMPAPPASTFLAFHPQDNNIIAIGMEDS
TIHIYNVRVDEVKSKLKGHSKRISGLAFSTNLGILVSSGADAQLCVWSIDTWDKRKSVTL
QLPASKAATGDTRVQFHSDQTRLLVFHETQLAVYDASKMECIRQWVPQDALSAPVSYAAY
SCNSSLIYASFCDGNIGVFDADTLKLRCRIAPSAYLSQAQMNGSQAVYPLVVAAHPQEPF
QFAVGLSDGTVKVVEPTELEGKWGVSPPADNGMLNGRTASSSATSSHTPDQIQR
>Sgl29634 E3_activity/RING/RING 26.7 3.4
MGLDESDLIDDGDGRGKSLSSSNVSCSICLELVTDNGARSWAKLQCGHEFHLDCIGSAFN
IKGVMQCPNCRKIEKGQWLYATGCRSFTDIMDDWPHDEDLYDFSYSEMFGVQWCPLPAFS
RLPTFEEGEFPSTAYHDFLGQHAVFAEHTAVSSSTHQCPYVAYYGPMHSSSSSSVGSVSD
GSSFNSSWGVPSRPSEMPASYAFPAMDPHYHGWEHQSLSFSANNNRLGGSDQPSAPSLTP
RSSRSNSDLPRSGSYVHPFVVSNSSGGRVGSSVTSSMIPPYPGSAARSRDRVQALQAYFQ
PPSTSPPMRAPIMPSARRSSSHRGLSQGAPLPSSSDQTAGGFFMFPSGTSNRSFPEADNP
VSSRFHGWERDHLASFPVTPGDRDSSWLPHHAAGGSSSIRQRHGSERPPSYNWS
>Sgl29690 E3_adaptor/Cullin_RING/DCX/DWD 20.7 4.0
MPTSEQQQQQLKSISFNQDSTCFSATTTSTFHIFNTHPFSPAFHRTFPFSLSSIHMLFRC
NIFALVDSHSHKLFLWDDHRSSFISELSFRSTVLSVRLRNDRIIVVLLHKIFVYNFIDLK
LLHQFHTVSNPNGLCEVSSLPNSFVLACPGLQNGQIRVEHFGPNKTDFISAHHSAVASMA
LTLDGALLATASTRGTLVRVFSTSDCSLLQEVRRGTDRAEIQSLAFSSNARWLAASSDRG
TVHVFNLKLDSGSPGNSGLPSPTEQPTSPRSPISSISFVKGVLPKYFSSEWSMAKFHLQE
GTRYIVTFGQQENTVVIVGMDGSFYRCTFDPVSGGEMTRVEYHNFLKPENSKEPAES
>Sgl29717 E3_adaptor/Cullin_RING/SCF/F-box 18.6 0.0
MRCSCCGDEEDEQDNFLHKPLLSPSPPQSIIFSKESTISPMNSNFSALTCRDILRIIFQK
LPITDLARASCVCRNWNSVASDREIQTASFMAPWKLKQIVGNPSSGSFWKDNSLSKFAIS
HRIVRGDSVASLAVKYSVQVIDIKRLNNMMSDHGIYSRERLLIPLTNPDLLIGSTCYIEL
DLYAKREAAVLYLEGSPQENMSNQSTSRATSDLGKRRVIESVRRSLQVDDEIARYYLSIT
DGDPRSALSEFSEDLRWERQTGLA
>Sgl29734 E3_activity/RING/RING 27.8 8.4
MMKQEQQPNKDDQKLITSPNNSNPNPCPICLGFISQESYLDHCYHRFCYQCIIRWTRVVS
SRSSALQQASSIKCPLCKTENISIIHGYDGITFQRHFIDQINGNSKFFTKDHKYRLLCYY
TGPEPSLLSDAFKVEHFWKSYKYLQQNIWLEKWLRRELQALMQEEDVEIIMHHILGVIES
FSRSHHPKGKLHLPQLKQEEFRALVTNAATPFLTARTNRFFVELELFLASGLNVEAFDRA
YRRCLGWKKPEETTEDIEETSTERQPIAPNMYFFDDDEVD
>Sgl29761 E3_activity/RING/RING 27.8 10.9
MCHNKTCCNHTHHAIIFFLILSLLLLPNAPNLNFLLHKFTNSPSRPSSKGGDGDAGFLSP
PCTTTKMVTAFLYGAVFTFVLMFVSNYCNHNNNDHYQQDPSASAGGSQSIPIPFHRTTSI
GLASGRPTDDQGGAEGGGVGVGYALLRTFPTFAYSVRRPPRKLGKGTSVCVICQYKFKDE
ELVRWLPDCDHLFHLSCIDEWLTSHKTCPCCRADLDVITNNHGSTTTTSNGINTTPNYIY
DYFNEYSYNVFSR
>Sgl29764 E3_activity/RING/U-box 23.9 1.2
MKLFHNDSTITIITTPIFLILLLGQTVAAQPSTTWPDSEQHEANFSPSMGVIIIVLVAAL
FFMGFFSIYIRHCSNDTSTNGRTGRGIGSLRRSRRAPRGLDQEVIESFPTFDYAAVKSEK
IGKGALECAVCLTEFEDDDTLRLIPQCDHVFHPECIDAWLVGHTTCPVCRCNLNDASTTV
LGEEPPHEASIHSVDVELGVVEAESSNNEEERNDNNNESMEQPLHGRTISRNRTIRNLSF
GRPRWLGKHARSMSTGHVSVKQWDDMERFTLRVPQEVRKQIMSRKLERTTSLLVLPRETS
SRRGYRTGPVFGEGSSRGRFGSTQSGTSQSDRWVFSLAPPFITRAPSVKSPKVVETTTTS
RGGSLRAFLFLLGLLLSQQVRAQVHSIAPGLEPNSSTADHSSRRPPREVIIVAILSVLLF
VTFYFIYLCCCIDDNFNQIGNWSGWRHPWGALAASLRRHSFKSTENELDPEVVKSFPTFE
YGTIKSSMIGKDTLDCAICLTEFNDKDMLRLIPKCDHVFHADCVDDWLVGHATCPICRLN
LTNVDLWHDHDHHNIPPFWRGQ
>Sgl29765 E3_activity/RING/RING 12.1 7.5
MATTATRDKQNKEYNEQQITRAISGDTTSDSESVLVFIPYSIAKVSIEKIKVGLRCANCL
NEFKDGEDETLRLFPKCRHVFHPLCLVDPCSVTCQCCKTGSTKDDDDEAIKAEAKTDKED
EDEDEDEDEDEDEDLARAEKVEDNNDKMVIIKLPEDVMQKIIVHAKLISQTGRPCSPTIF
FRKKNNVELGEVVQD
>Sgl29766 E3_activity/RING/RING 27.8 10.9
MCHNKTCCNHTHHAIIFFLILSLLLLPNAPNLNFLLHKFTNSPSRPSSKGGDGDAGFLSP
PCTTTKMVTAFLYGAVFTFVLMFVSNYCNHNNNDHYQQDPSASAGGSQSIPIPFHRTTSI
GLASGRPTDDQGGAEGGGVGVGYALLRTFPTFAYSVRRPPTKLGKGTSVCVICQYKFKDE
ELVRWLPDCDHLFHLSCIDEWLTSHKTCPCCRADLDVITNNHGSTTTTSNGINTTPNYIY
DYFNEYSYNVFSR
>Sgl29769 E3_activity/RING/U-box 29.2 4.2
MKFFHNDSTITIITTPIFLILLLGQTVAAQPSTTWPDSEQHEANFSPSMGVIIIALVAAL
FFMGFFSIYIRHCSNDTSTNGRTGRGIGSLRRSRRAPRGLDPEVIESFPTFDYAAVKSEK
IGKGALECAVCLTEFEDDDTLRLIPQCDHVFHPECIDAWLVGHTTCPVCRCNLNDASTTV
VGEEPPHEASIHSVDVELGVVEAESSNNEEERNDNNNESMEQPLHGRTISRNRTIRNLSF
GRPRWLGKHARSMSTGHVSVKQWDDMERFTLRVPQEIRKQIMSRKLERTTSLLVLPRETS
SRRGYRTGLGFGEGSSRGRFGSTRSGTSQSDRWVFSLAPPFITRAPSVKSPKVVETTTTS
RGGSLRGKGALECAVCLTEFEDDDTLRLIPQCDHVFHPECIDAWLVGHTTCPVCRCNLND
ASTTVVGEEPPHEASIHSVDVELGVVEAESSNNEEERNDNNNESMEQPLHGRTISRNRTI
RNLSFGRPRWLGKHARSMSTGHVSVKQWDDMERFTLRVPQEIRKQIMSRKLERTTSLLVL
PRETSSRRGYRTGLGFGEGSSRGRFGSTRSGTSQSDRWVFSLAPPFITRAPSVKSPKVVE
TTTTSRGGSLRDDNFNQIGNWSGWRHPWGALAASLRRHSFKSTENELDPEVVKSFPTFEY
GTIKSSMIGKDTLDCAICLTEFNDKDMLRLIPKCDHVFHADCVDDWLVGHATCPICRLNL
TNVDLWHDHDHHNYAVLGEGNESETLRMRSLSSSPQPPGLFEGLSRSLSTGHVSVKQWED
KERYTLRLPWEVRKQIMSRSRSSGRFGSVNVDLRRGKSDSWVFNLTPSFRKQLNKVENVS
ATSTSTSIKEESSINVSVDDEPTQLPV
>Sgl29770 E3_activity/RING/RING 39 5.5
MEATMSPEAFILYVSFYIVLSILSILWVCSIVCRSHWFFQGIRDHFIDDEPSIPLYLEHP
SLQTVVIEDLPKFSYSSQGIVDPRIDTSLRINTECVVCLGEFEENETIRMLPRCGHIFHK
DCIDIWLRLRFTCPLCRATLLDIVDMNPPQNRPSRAEV
>Sgl29771 E3_activity/RING/RING 36 5.0
MNDKSPLISYIMNIVFYIVLSILLVLWLLTIICRRHRALQTTSSQHRRQAVGPDHVIAFS
VNHELPPGLDTSAIETFPKFTYSGSDPVPGKMKMTGECAVCLGAFEEKETLRLLPKCGHV
FHAECVDIWLGIHATCPFCRAILLPPEDAASSGDRPTQFEVVINVNDGRER
>Sgl29772 E3_activity/RING/RING 31.9 11.2
MPSSSSSKQTVLYWITFSLLVAMATSIFAFLVFFLVTRLCLKRRRIGADVDPGSTVMEDP
YTGGPRGVDQTVIDTFPVITYTAVQGKKVCRGMNVCVICLAVFKEGETLRSLPKCGHVFH
SHCVDSWLKTHSTCPCCRASLVTRSGGFFSRVCWPSW
>Sgl29773 E3_activity/RING/RING 11.9 7.8
MKSHPKAIALGVVIIEIILCFLIYITCAIIRRRRRWRQQRQEQQRQYNEQQITRAISGDT
TSDSESVLVFIPYSIAKVSIEKIKVGLRCANCLNEFKDGEDETLRLFPKCRHVFHPLCLV
DPCSVTCQCCKTRSTKDDDDEAIKAEAKTDKEDEDEDENEDEDLARAEKVEDNNDKMVII
KLPEDVMQKIIVHAKLISQTGRPCSPTIFFRKKNNVELGEVVQD
>Sgl29778 E3_activity/RING/RING 40 6.9
MGIVLAIVTISVVVMFVVLNLCCQSQVGHEARASDGPSHRARKGLDPSVIETFPVFKYWE
VAARAHHTHSGPLECAVCLSQFEDDDQLRLLPKCNHVFHVECLDPWLKGHSTCPLCRVDL
VPEASDLDELDRIELGLASNGPGGEVNQGNNNNNVDCVSRDDIEEGYMGKYRRWKSMGHV
QVAEMVEGECWKRFTLMLPMKEMMSFGEVTNKFKRTKSSI
>Sgl29779 E3_activity/RING/RING 34.8 9.4
MFGASSDRLVIGFALVIATVFVAAIFVVINLWCKSQSGHQPRAHDSPGYRASDGLDPCVV
ESFPVYKYSEVAARSGPLECAVCLSPYEPDEKIRVLPKCNHVFHMECLHPWLKDHSTCPL
CRIDLVPKTSEFSQMESGQVNGLEDEVNKGGNEDNDAPLEARVDIEEGQGHFRKYRRCKS
TGHLAEIGRVEIECWNRFTLLLPEDEEAMKFGGVTNKFRRSRSSI
>Sgl29782 E3_activity/RING/RING 33.8 8.9
MIFSIISHHPKPYYKHAPTLFLSITLRLIAPLLVSAQDLNNNILGSNPVVSGVIFTIVAV
FVFATLIVVNFCFQFQGGNQARADDGPGQRARKGLDPSVIESFPVFKYSEVAAHQTQSDS
LECAVCLSQFEHDEQLRMLPKCNHVFHVECLDPWLKDHSTCPLCRIDLVPETIELDRADD
MGLANGPDGVVINEGENDGNNNNVNEVRVDIEEGGLGKFKRWKSMGHVAEGKMVEGECWK
KFTLMLPEKEEMKFGDEVTSKFTRSRSSI
>Sgl29784 E3_activity/RING/RING 36.6 7.5
MRFFFTLLLLVLSLFYNPKLLVRAQYIINVDNHQHHSHNSRWNTLNACFFVVLLIVVSYL
VYRYFDRYYQQGWWAHETPNQAQLGLDPSTLETFPVFLYSEISGLGDDKGPLECSVCLGT
FEKDEKVRQLPKCNHMFHLECVNRWLASHTTCPLCRAELAHRPDDSTKTRLDSADGSMNG
SSAQAVTATVDDVV
>Sgl29785 E3_activity/RING/RING 36 6.3
MNLRHSSSTFIFIILLLYSLDHLPLTTAQDTSSDDPSLGKKRYYIARPYMVLLHAISTIL
VMCQFFYKGLSILLRGDNNVPNNRALVGLDQSVLNTFPIIVYSDEAKPNNSLVECVICLA
LFEKDETLRMLPKCGHIFHVDCLDPWLVGHSTCPLCRANLVPQTGGLARTGRGVGEVRND
VVEARRD
>Sgl29786 E3_activity/RING/RING 33.2 9.7
MGLLAISVIIVLTILYYIANICYNSFLEQPSPELGPCDQVGLNPTILNDFPIFTYPNVAG
HIEPMLGPLECAVCLSPYKEEQFLRLLPNCDHLFHLYCVDRWLEANTTCPVCRADLIGEL
SQSSFGLIRSESSQVESTCTEELGNGLGIGYDNTPNENIVEMTQEILDWEATKIWRSNST
GHTTNSYEPEEDTERFRPTS
>Sgl29848 E3_adaptor/Cullin_RING/DCX/DWD 15.2 0.0
MKLQQTKGINKTNGFTRNSFKFISSCIKTVSTGVRSASASVASSISSDSNGVKDQVLWAC
FDKIELSPSIFKRVLLLGYTNGFQVLDVDDASVVTELVSKRDGPCTFLQIQPFPAESEGS
EGFKASHPLLLVAAGDETKGPDPTQRRRDGLVRDGYVESQTGNVVNSPTAVLFYSLRSHN
YVHVLRFRSAVLTVKCSPRIVAVGLASQIYCFDALTLENKFSVLTYPVPQMAGMGMVGIN
VGHGPMDVGPRWLAYASNNPLLTNTGRLSPQNLTPSPGVSPSTSPSGGSMVARYAMESSK
HLASGLISLGDMGYKTFSKYCHELLPDGSSSPVTSSSGWRVNKTLANSSDTDIAGMVVVK
DFVSRAVIAQFRAHTSPISALCFDPSGTLLVTASIHGNNINIFRIMPSSSKNGVGSHNYN
WTSSHVHLYKLHRGITSAVIQDICFSQYSQWVAIITSKGTCHIYVLSPFGGECGLQVDNS
HVDGPTFVPVLSLPWWSTSSYIVNQQSFSAPPPSPVTLSVVSRVRTGNSGWLNTVSSAAS
SAAGMGSVQPSAVSAVFHCSMPKGLPPRRSNALEHLLVYSPCGHLIQYGLIPSMGMETTD
TVSRNGSGVQDEDLKVKSEVIHWWDVCRRADWPEREECIKEMSFGSKGPSGTVLETSDSE
DGNSHGKGEELHEQSTLYLSKAEVQMNYGRIPTWQNSKIHFFSMNSMIPDRQKYSVDDDF
GGEIEIEKVPNFEIEIKRKDLLPVVEHFHKLKPDWSNRGAIGERYPNSTSEAHLAEDKYP
SPAVVHPQPVQNSQFGPFGQATEMDKVKSYLGIAQNQIIKNGAIAPSTFPKPILTQNSLK
TDNISAMEISPPENSCIVNSPSPVNNESLSVERANRKEVQSSSSVGGSEDSNVSSNRSDF
SMNVADESSVQDPLEFGGYFQEEYCKAAPLDENHELSEVVTDVDSSSSPRDKEKSEEDGE
SDELLGCVFAFSEEG
>Sgl29849 E3_adaptor/Cullin_RING/DCX/DWD 14.7 0.0
MKNQQTKGINKTNGFTRNSFKFISSCIKTVSTGVRSASASVAASISSDSNDVKDQVIWAC
FDKIELSPYNSKRVLLLGYTNGFQVLDVDDASFVTELVSKRDGPCTFLQIQPFPAESEGS
EGFKASHPLLLVAAGDETKSPDLTERRDGVVRDGFIESETENVINSPTAVHFYSLKSHNY
VHSLRFRSAVLTVRCSSRIVALGLASQIFCFDALTLENKFSVLTYPVPQMACVGMVGINI
GYGPMDVGPRWLAYASNNPLSTNTGRLSPRSLTPSPGVSPSTSPSSGNVVARYAMESSKH
LATGLLSLGDMGYKKFSKYYHDLLPDGSNSPVTSSSGRRVNKTSANSPESDNAGMVIVKD
FVSRAVIANFRAHTSPISALCFDPSGTLLVTASIHGNNINIFRIMPSCSKNGAGTQNYNW
TSSHVHLYKLHRGITSAVIQDICFSQYSQWVAIISSKGTCHIYILSPFGGECGLQFENSH
VDGPTFVPVLSLPWWSTSSYTINQQSFSASPPPPVTLSVVSRIRTGNSGWLNTVSSAASS
VAGMGSVQPSAVSAVFHCSRPNGLPLRRSNFLEHLLVYSPCGHLIQYGLIPSMGVETTDT
ASKTGSASLLQVQDEDLKVKSEVVHWWDVCRRADWPEREECLKDVSFGTNDPSKMVLQTS
ESEVTDNHGKVEGLHEQSTLYLSNAEVQMNYGRIPTWQNSKIHFFAMDHAVPNKQKYSID
DFGGEIEIEKVPDFEIEINRKDLLPVVEHFHKVKPDWSNRGAIGETNPTTTSDARVAEDK
YPSPAVIHPQLTQNSQFASFEQAAERDMVESYLGIAQNQLIKNGAIVSSTFPKPIPTQNS
LKIDNTSPMEISPPENSCVVNSPSPVNNKSLLAERSHRKEAHSSGSVVGSEASNVSSNRS
DFSMNVVDESSVPDPLEFGGYFQEGYCKAAPLDVSHELSEVVTDVDSSSSPREKKSEEDG
ENDEMFGCVFAFSEEG
>Sgl29862 E3_adaptor/Cullin_RING/DCX/DWD 56.6 1.9
MATEQMTDYERKRLENIKRNSEMMASLKIHSHISDLSSTTKHLREEKSYKQRSVKKPKVE
TPVVIRRSLRIQELPPDSIGLPEDCNDLPVTSSKPKALKMSSSPELRPLPREDLSMEITY
EGQKGSHLALVEKLARFTRKTKSDDEVKHLNSSKKLKFEKVDVVEPTNPCSLKLDNDNVA
NITPRRSTRNTKSDGLNNHSNSPLKPERVKLEEPFDPCNGLLNSPTMFERVKLEEPIDLR
SMELEHYNIARVVPGRIFSIRLFPTTEMTMVVVGNKNGHLGFWDAKPQSGEEEDVIYLYK
PHSAPISGISVHPFTLSKVYSSCYDGLLRLMNIEREKFELIYSSSSGFFSLAQKADDVSS
LYFGTGSGELNMIDARTRDISSSWPLHEGRINTIDFSPQNTNFMATSSTDGSACIWDLRN
MNVKIRDKHPDLNVVSTVRHARAVHSAYFSPTGSFLATTSLDDKIGVLGGANFEETFMIP
HDNWTNRWVSSFRAVWGWDDTHLYVGNMKRRIDVLSVTQKKLVYKLESSNMTAIPCRYDA
HPCNAGMLATATSGGQVYLWTASS
>Sgl29900 E3_adaptor/Cullin_RING/SCF/F-box 34.7 0.5
MKRTMTSPPNLPPKKSKFNQPLKINDPNSNPNPIPNSDSDSDSPESQFTKLDENLLYEVF
KHADAKTLATASCVSKQWRLTAQDERLWELICTHHWSNSVNCGTQQLRSVVLALGGFRRL
HARYLSKTAVTSPTSPPTPSVFPTLSATAASSSSSSSSIQRQVVKRNGSKRWGKDEVNLS
LSLLSISFYEKMNSAYKKQ
>Sgl29910 E3_adaptor/Cullin_RING/SCF/F-box 14.6 0.0
MELESPQKTHLKSSLKTPSSLSLSSSFPEEVLEHVLSFIDSHSHLNSVSLVCKAWYEIER
WCRRRIFIGNCYAVSPSIVIRRFRDLRSVTIKGKPHFADFNLVPDGWGAHALPWIAAFSE
AYPSMEELRLKRMVVTDEALELIGKKWRNFKVLVLCSCEGFSTEGLASIAANCRNLKTLD
LCESEVDDLSGNWISHFPDSYTSLESLNVACLVSELRFTSLERLVSRCPNLKSLRLNRSV
PLEKLPILLEKAPQLIDFGTGSFLTELNTEAHEKLSRAFAGSKGLKSLSGLYDVIPTYLP
ALYPVCSGLTSLNLSYATIHSPDLIKLLSHCQSLQRLWVLDYIEDSGLEVIAESCKDLRE
LRVFPSEPYVQEPNVCLTEQGLVSVAMGCPNLQSVLYFCRQMSNEALFTIAKNRPNLTRF
RLCIIEPQVPDYLTNQPLDEGFGAIVEHCKDLRRLSLSGLLTDRVFELIGAHAKKLEMLS
LAFAGDSDLGLHHVLSGCNLRKLEIRDCPFGGSALLVNAAKLETMRSLWMSSCQVSYGEC
KLLGRKMPRLNVEVMDERGHPNSRTDDCSVEKLYIYRSIVGPRADSPDFVCTMSEDLASP
LRCTE
>Sgl29924 E3_adaptor/Cullin_RING/DCX/DWD 113.4 27.0
MYAIKFSSAGVTIAYNLRDPVQLVKIEELKFANLSKISVRWNLLAMHRVGSAGNTSGSNR
PRKEKRLTYVINASDDTKHCAGVNCLAVLKSNGSDRSECLFTGSRDGTLKRWTIDEETAT
CAATFESHVDWVNDTVLVGDHTLVSCSSDTTLKTWNCLSDGLCTKTLRQHSDYVTCLAAA
GKNSNAVASGGLGGEVFVWDIEAALAPVSKSNDSTEEDASNGVSGGGSNLPITSLRTINS
SNSISLHSPPNHGYTPTAAKGHKESVYALAMNDSGTLLVSGGTEKVVRVWDPRSGSKTMK
LRGHTDNVRALLLDPTGRYCLSGSSDSMIRLWDLGQQRCVHSYAVHTDSVWALASTTSFS
HVYSGGRDQSLYLTDLSTRESILLCTEDYPILQLALDDESIWTASTDSSVHCWPAEGHNP
QKMFQRGGSFLAGNLSFSRARASLEGSTPVPVYREATLKVPGIPAIVQHEILNNRRHILT
KDTASSVKLWEITRAL
>Sgl29978 E3_adaptor/Cullin_RING/SCF/F-box 15.8 0.0
MKMVSCKSSASNTTPIIPNDVIVCEILPRLPVKSLLRSKAVCKDWYDLISTPQFIKSHLQ
LSLFSSPRFFTMNDQGHWRKFYTFTYNEGRSNRKEWVHLDSSAWTDELVHRNKYGIIGCC
NGLVCLSVQHNKKHEDGTTTLSFIVWNPATQECREISPPTEDGRLLCWSGFGYTLAHDDY
KIVCILSDCVWIFSLREGQWKQIMGFPSYDKPMFKGVFVGDVLYCKVVSSLEETDANIIS
LNLVKEQFEEIPLTNLPIANVVSISLYVIKGCLSVHSEVEPQDVWMLKRQDDWKSWEKVF
RFPSNIIVNHKGITWDGKILADHWGKLVLVDPNCNSLTDYMESADCYCPDDFWGWPYGAE
TPQHVESLVSPFGVAQDVNGSKAYV
>Sgl29979 E3_activity/RING/RING 20.1 10.2
MSTQVVKVRRDKVAACMKCPICNKLLKEATTISLCLHTFCRKCIYDKLSDEDVDCCPVCD
VHLGCIPVEKLRPDHNLQDIRAKIFPLKGRKVEAPEIAPAVSAPVKRKERSLSSLVVNTP
RVSMQGVVTGKRTRAGRKGSVPRSASPATEETNKKEEDSVEDHLDGSSSPETLNKIIQNK
KQSSSTKSSNDQTRGEGMENNNEGREGKVDLWKPLNTLVEAANRSKFSKSNVQGASHSKA
DASNSGDADIGVNKTRTDEIGQGDESEGDKSGNPPVSGPVKRNRLRPSNKIRSSVPAESL
SSQVVVNEARQNWKDGPIWFSLVASEEQEGGEPLPQVSAAFLRVKDGSMPVSSIQKYIMK
KLELASEAEVQIMCEGLPVMPHLKLSSLLEAWLRTSATQKKIQTTVGDSAKEFVMVLSYS
RKVVAPNS
>Sgl29983 ULD/UDP/UFD/PB1 59 0.0
MLSSERDKYTIDFEETELRLGLGLGLGLAGSGSCEVDQLAKNNNGKRGFSETEGDSSVDL
KLNLSTSTTTTATNTTTTTTNTTTTSNIVKDVKVEQSVTSSVADQKLKDKVTPADPAKPT
PAKTQVVGWPPVRAFRKNIVSVQKKSSEEQSDQKASNNAVTHAAAFVKVSMDGAPYLRKV
DLKLYKSYQDLSDALGKMFSSFTIGNCGSQGMKDFMNESKLIDLLNGSDYVPTYEDKDGD
WMLVGDVPWEMFVGSCKRLRIMKGSEAIGLAPRAVEKCKNRC
>Sgl29984 ULD/UDP/UFD/PB1 63.1 0.0
MEMNKKDSTQHEDTELRLGLPGTEFKTTQIISNNKRSFSEIKEESTSNDDDKSTKITAPP
PKAQVMGWPPVRNYRKNCLQAIKKEAENNGGVYVKVSMDGAPYLRKIDMKVYKGYPELLK
SLEDMFKVKVGEYTEREGYNGTEFVPTYEDKDGDWMLLGDVPWEMFTNSCKRLRIMKGSD
ARGLGCLA
>Sgl29985 ULD/UDP/UFD/PB1 63.4 0.1
MEKSNINLSYHHEDTELRLGLPGTTNNGSEKKRSFSEINEESTSGVEDCHDDHLLSQQKV
QAIGWPPIRSYRKNCLEVTKSREESTRMYVKVSMDGAPYLRKIDLKLYKDYNELIKTLED
MFKFKTGKLCNKEAINNGSEYEATYEDKDGDWMLVGDVPWEMFTSSCKRLRIMKGSEARG
LGCCLA
>Sgl30083 E3_adaptor/Cullin_RING/SCF/F-box 17 0.0
MKMVSRKSSSSTTTPTIPNDVIFCEILPRLPVKSLLRSKAVCKDWYDIISTPQFIKTHLQ
LSLFSSPRFFTMNDQGHWCKFYTFTYNEGRSNRTEWVHLDSSAWTDELVHRNKYGIIGCC
NGLVCLSVQHNKKHEDGTTTLSFIVWNPATQECREISPPTKDGRLLCWGGFGYTLAHDDY
KIVCILSDCVWIFSLREGQWKQIMGFPSYDSPMFKGVFVGDVLYCKVVSSLEETTDANLI
SLNLVNEQFEEIPLTNLPTANVVSISLYVIRGCLSIHSEDEPQDVWMLKKQDDWKSWEKV
FRFPSEIIVNHEGITWDGKILADHWGKLVLVDPNCNSLRDYMDSADCYCPDDFWGWSYRS
EIPQHVESLVSPFGAAQDDNGNKAFV
>Sgl30118 E3_activity/RING/RING 18.3 1.8
MLFQVGGQGTRPTFFEMAAAQQLPSSLRSALTYSLGVMALRRPILHRVLDYEDEFFALLM
LVLETHSIRTTDASFSESLYGLRRRAVNIALKKDTLHSDSTNGVQHSGMEKHQKILSVVF
LVVLPYFKSKLHSIYRRERETAVQESLWGPGGEGFDGVDYLDVAENPVDQTASDLELSSR
ARILQGVTKVITACYPLIHAGHEGLAFAYQTLYLLDATGFYSLGLHALGIHVCRATGQEL
MDASSRISRMRSRERERLRGPPWLKKLQGALLSCMYAVLDYSQTGLIAAVFVFKMMEWWY
QSAEERMSAPTIYPPPPPPPAPKVAKEGIQLPSDRTICPLCSERRANPSVVTVSGFVFCY
GCIFKYVSQYKRCPVTLIPAEVEDIRRLFHDM
>Sgl30122 E3_activity/RING/RING 18.1 14.3
MEIGQSSSSKSSDEVWAKLVPSDSSYASIEISSDDATVCSQISSTSDKLEWCQIIRNSDR
CSATIRNKRTSLILVDGTTLMGDDVVGLKCGSEIVPASTREGQLSYKFEVMPVQEQCPEK
YLKISLDAENTKCGICLNVWHDVVTVAPCLHNFCNGCFSEWLRRCQEKHSSVLCPHCRAA
VHFAGRNHFLHGIEENILQADASLRRSAEELAVLDSYASIKSNLVVTNGKKNRRKRAHSP
TPIHEETDGVDLPCPQCGTQTGDFRCNASTVHLQCHDCGGMMPLRSDINIPQHCLGCDRA
FCGAYWRTQGVNRTDLRPICSSESFRPISERRVSSIPPVAHERNQFEQNITNSCISQTGK
TLQEIISEWTIKFNNREIDRSRLLVRHGEMIAAGTHVCNECFDKLVSFFLYWFRISLPVH
LLPPEASNRDDCWYGYACRTQHHSVDHARKRNHVCRPTRGSHT
>Sgl30149 E3_activity/RING/RING 32.5 6.7
MENNDQVRQPQEQQQQSQEQQQQSQEQQQQAPKQISLDQLEQVESDHVFALALQQQESTT
TFTMLETIESDSTDDDVLDDEDEEEEEEDEEIGSSSSHDFDSNFDTQEFYGELEYLEEDE
EGSYIDDEFEEDEIDPDEMSYEELMALGEVVGEESRGLSTEEITSSLSSYVHKMVQCKTI
IDRCVICQSEYEEGENLAALHCQHPFHEDCINQWLQIKKVCPICSIEITPTVPPSSNPDI
PDKI
>Sgl30166 E3_activity/RING/PHD 38.2 5.7
MAESPIKAKKRLDLKSPTKPSNSPISFLPPQTPNTDFNSSPIESTPLRRSSRRLSQNAND
FKLTPEKSVKQSLIKTLEKSPKTPKSSKRSKLSSPHNQKVLNEDPIHPKSPALTEERKRK
RGNELGDVAKTRAQVRARAQNVPKKRVYYKKVVYDKAEFAVGDDVYVKRRENASSDDEDP
EVEECRVCFRAGQTVMIECDDCLGGFHLECLKPPLKEVPEDDWTCEFCEAKKLGKKVQLP
VPPKGMKRARTLKEKLLSSDLWAARIESIWKEVDRTYWFRAHWYMIPEETEAGRQPHNLR
RELYRTNDYADVEMESVFRHCYVMSPKEFAKAGNAGDDVFFCEYEYDIRWHSFKRLAEIN
DVEEDGDNDDDDSASDEDWKSTKDPESESEEDMDFEDENDKRKSFGPPSQELAANSRKGH
IFGLQKIGTKSIPKHVRCHKQTELERAKQTLLLATLPKSLPCRDKEMEEITKIIKDAISD
DQCLGRCMYIHGVPGTGKTMSVLSVMRSLKSELDSGNIKPYSFIEINGLKLATAENIYRV
IYEALSGHRVSWKKALNFLNERFSEGKQVGKGKNKPCILLIDELDLLVTRNQSVLYNILD
WPTKPNSKLIVIGIANTMDLPEKLLPRISSRMGIHRLCFGPYTYQQLQEIIMSRLKGIDA
FDKQAIEFASRKVAAISGDARRALEICRRAAEIADYRIKSHISLANPPSVGKTHVVMADV
EAAIQEMFQAPHIQVIRSSSKMAKIFLAGMVRELYTTGMAETTFEQLAVVVSCFCTSNGE
QFPGFDTLLKVGCKLGECRIIICEPGYRHRLQKLQLNFPSDDIAFALKGCPELPWLAKYL
>Sgl30525 E3_adaptor/Cullin_RING/DCX/DWD 52.6 1.1
MASEQMTEYERQRLENIKRNADMLASLNVHSHLSNLRFREEKRRKYEKKPIQEASRTSLR
TQGIPPHFEGLPEEYNESLRPSKPENKAPEAVSFAGPLYMRDAYKGAGSHRTLVDKFTCF
KSVGPSFDHAGIVKAHFDFNSLKLEPRNVARVVAENTLAVRFLPTTSMTMVVVGNRDGEL
GFWDVGKGNEGDEAIHLYHPHAAAVSGISVHPFALSKVYTTSYDGFLRLMDIEREKFDLV
YSNTFGYCLYSISQPPNDPNSIYVGEGLGGLKVFDERARENVFSWCLHEQRINTIDFNLA
NPNIIATGSTDGLACLWDLRKMDVTQGNCKALHTVDLGKAVLSAYFSPSGSNLALSVDGY
ISVVCGANYEDLFTICERYRCHGSKVGHWATCPSRAVWGWDDNHIFAGDSKRSINIVSVS
ERKIVYSLESPLMSAISSRYHAHPYTVGMMAAATGGGSVYIWTADL
>Sgl30874 E3_activity/RING/RING 28.1 10.5
MTSGKTNLVMTVIGFVVSTLFIVFICTRLICARIQLRTSRRNFRRHTASRSNLTTLEGGL
NGIQPPISANFPAKKYGDDYFSSAESGQCSICLADYQTEDVLRIIPYCGHYFHIKCIDLW
LLQHCTCPVCRLSLREANERKRSMQFMSSSRSHPNTDVPAVSPRHCRPMLRTPETHVIGP
IQEDQLLSNVIMNSTGDNNSQLPEENDPVKDPKKKNVESPSFS
>Sgl31025 E3_activity/RING/RING 17.9 4.5
MECLHRFCRECIDKSMRMGNNECPACRTHCASRRSLRDDQRFDQLIAVLYPDIRKFEEEL
MYELEDVDLQKICYEVPPKRKKKYFVLNDYFFAQIQESITQVLIKQSEALGKKRSSNKDA
AGPSVTRSQR
>Sgl31060 E3_adaptor/Cullin_RING/DCX/DWD 66.1 11.3
MAQFQLSETYACVPSTERGRGILISGDPKSNNILYCNGRSVIIRNLDNPQKVEVYGEHAY
PVTVARYSPNGEWIASADVSGVVRIWGTHNGFVLKNEFKVLSGRIDDLQWSPDSLRIVAS
GDGKGKSLVRAFMWDSGSTVGEFDGHSRRVLSCAFKPSRPYRIVTCGEDFLVNFYEGPPF
KFKHSQREHTNFVNCVRFSPDGSKFITVGSDKKGITYEAKTGEKLGELSAEDGHQGSIYA
VSWSPDSKQVLTVSADKTAKVWKISEDGNGISIKTLTSGSGGVEDMLVGCLWQNDHLITV
SLGGVINVYSASDLEKGPLTLSGHLKNVSALIMFKSDESMVLSCSYDGIIIKWIRGVGYS
GKINMKDHAPIKCFAAVEGEIILSGFDNKVEFMDVSLIFNSLHFFSAAFTNLMSPKDLPL
ILLQLTLAKLAFIH
>Sgl31061 E3_adaptor/Cullin_RING/DCX/DWD 65.9 2.5
MYPSPYQCNLACTHASTKCTPFKALYGREPPSLLRLPKGGVVVSAVDELLEERDAILDDL
KANLLRAQQRMKNQEDEHRREVKYEVGDWVYLKLQPYRQQSLAKRPYEKLSARYYGPYEI
IERIGEVAYKLQLPNSAKIHPVFHVSLLKSAVGDAHTSPDLPKQLNEEMELEVQPESVLN
IRVTSGDHQEVLIKWDGLPEFDATWEDLEAVKRKFPRFHLEDKVAVLAGGNATPPQDGPA
QQRPVVKYTYARRNSRKGKSVWRAPIQEDDCGPAEHVDVGSQPKDLSVAINAPEVVLVAT
DSGAVLLNGLKVLSSVELGFTVTACALSPDGTEAILGGQDGKLHIYSVSGDALTEEAVLE
KHRGAITVIHYSPDVSMFASGDANREAVIWDRSTREVKLNNMLYHTARINCLSWSPDNTM
VATGSLDTNVIIYELGKPASSRTTIKAAHLGGVYGVAFADEHSIVSSGEDGCVRQWTITS
E
>Sgl31132 E3_activity/RING/U-box 117 0.3
MEESLITTTPTTPSTTTEVKETRDPPSISMDGELAQNIHLVISDIGKISTNGGFCDLFKK
DCNDLGRRISLLSYLVDEICDSSSPSSSSSQSHSDNNNDEDYDDDSSSNSCFVDLFVALQ
DSKRLLLAASSFDPNEDGATKRVSFQFQCVTWKLEKALGNIPYEQFGISEEVQEQVELVR
TQLKRATERYGPLNSSKIIRAASQPLLNELELLQSGNKGFGCLHLDNTGNIDHEVRRKVK
TSRSGNSSTSDSHDVSERVELSSVAVPECVSSSVEEEDGCSGETEEESMKPDSVSIPEDF
LCPISLEIMRDPVIVSTGQTYERSYIQRWIDSGNMSCPKTQQKLQHFTLTPNYVLRSLIY
QWCAKNNIEQPTALMTGKIKKSDGTFRDVSGDIAAIQALVRKLSSRAVEDRRTSVAEIRS
LSKRSTDNRILIAEAGAIPVLVNLLTSDDELTQENAVTSILNLSIYEHNKELIMLAGAIP
SIVQVLRNGSMEARENAAATLFSLSLADENKIIIGASGAISALVELLQSGSPRGKKDAAT
ALFNLCIYQGNKGRAVRAGIIAALMKMLTESSGTMVDEALTILSVLAGHQEAKVAIVKAC
TIPVLIDLLRTGLPRNKENAAAILLALCKRDMENLVSLGRLCAAVPLTEITKNGTERAKR
KATSLLELLRKHQQQS
>Sgl31341 E3_adaptor/Cullin_RING/SCF/F-box 12.3 0.0
MVEKKWTTLQSRKHHCNEANDLFTRLPDDLLLFIMSFLTMKETARTSVLSRRWNYLWRCC
PVLIFEDSSAMKRMFAHYIVVPLERSRFLRRVNGVRERHVGGYVHELRVTFDLNKTALLP
I
>Sgl31635 UBD/UBC-like/UBD_UBC 109.6 0.0
MKLCPREVEKLALHNAGFLAQKRLASGLRLSYTEAVALIATQVVVHSEKFYNFRSSVFID
FEFCSCWKQECGGTDGHWKEASWKGPSETPYDGGVFQLAFAVPEQYPLQPPQVRFLTKIF
HPNVHFKTGEVCLDILKNAWSPAWTLQSVCRAILALMAHLEPDSPLNCDSGNLLRSGDLR
GFQSMAKMYTRLAAMPKKG
>Sgl31681 E3_activity/RING/RING 12.9 9.5
MGANSSKEETISSSPTWNNQYGNQQPGYSEPYYVPESQYHHQPVQQPYPPAQTSTPTPTY
AGPTHEHNKRFERMYSRIADEYSSLEQVTQALARAGLESSNLIVGVDFTKSNEWTGAKSF
NKRSLHHIGGYGDGPNPYEQAISIIGKTLAAFDDDNLIPCYGFGDGPTSFAPVIEMAMTI
VERSGGQYHVLLIIADGQVTRSVDTEHGRLSPQEQRTVDAIVEASKCPLSIVVVGVGDGP
WDTMKEFDDNIPARDFDNFQFVNFTEIMAKSTHPTRKETEFALAALMEVPLQYKATIELH
LLGQRRGTSPERVPLPTPMYNAPSQINTAPSFNYPMPSDSTSFQSSAPSLNYSMPSHSTS
FQSSAPSFNYSMPSHSTSFQSTAPHYYENYSHASTAPPVPSSNYNSDPPDASSDYDNQLC
PICLSNKKDMAFGCGHQTCAECGQDLLNCPICRSTIQTRIKLY
>Sgl31723 E3_adaptor/Cullin_RING/Cullin 741.3 4.8
MISSYLELSPLNRLPSPSSLPLKHLSEGETRMSNQKKKQFQIEAFKHKVVVDPKYADKTW
RILEHAIHEIYNQNASGLSFEELYRNAYNMVLHKFGEKLYLGLVGTMTAHLKEISKSVEI
AQGGSFLEELNRKWTDHNKALQMIRDILMYMDRTFVPSTHKTPVYELGLNLWRDNVIHSS
NIQTRLLNTLLELIQKERTGEVINRGLMRNIIKMLMDLGASVYQEDFEKPFLEVSANFYR
VESQEFIECCDCGDYLKKAERRLNEEIERVSHYLDLRSEFKITKVVEREMIANHMPRLVH
MENSGLVNMLLDDKYEDLGRMYSLFRRVDNGLGTIRDVMTSHIRETGKQLVTDPEKVKDP
VEFVQRLLDEKDKYDKIISLAFTNDKTFQNALNSSFEYFINLNTRSPEFISLFVDDKLRK
GLKGVSEEDVEIVLDKVMMLFRYLQEKDVFEKYYKQHLAKRLLSGKTVSDDAERSLIVKL
KTECGYQFTSKLEGMFTDMKTSQDTIQGFYANHGAELGDGPTLVVQVLTTGSWPTQPSVP
CNLPAELSLLCEKFRSYYLGTHTGRRLSWQTNMGTADIKAIFSKGQKHELNVSTFQMCVL
MLFNNADKLSYREIEQATEIPAPELKRCLQSLACVKGKNVLRKEPMSKDIGENDVFLFND
KFTSKFYKVKIGTVVAQKESEPEKQETRQRVEEDRKPQIEAAIVRIMKSRKVLDHNNIIA
EVTKQLQSRFLPNPVEIKKRIESLIEREFLERDSADRKLYRYLA
>Sgl31808 E3_adaptor/Cullin_RING/DCX/DWD 54.1 4.7
MGATSDPSTNPEPVSDEQQKQRSEIYTYEAPWHIYAMNWSVRRDKKYRLAIASLLEHSLN
RVEIVQLDDSTGEIKSDASLSFDHPYPPTKAIFIPDKDCSKPDLLATSSDYLRIWHINQD
SSSNSSKVELKSLLNGNKNSEYCGPLTSFDWNEAEPRRIGTSSIDTTCTIWDIERETVDT
QLIAHDKEVYDIAWGGAGVFASVSADGSVRVFDLRDKEHSTIIYESSEPDTPLVRLGWNK
QDPRYMATIIMDSPKVVVLDIRFPTLPVVELQRHQASANAIAWAPHSSCHICTAGDDMQA
LIWDLSSMGQPVEGGLDPILAYTAGAEIEQLQWSSSQPDWVAIAFSNKLQILRV
>Sgl31839 E3_activity/RING/RING 20.7 15.6
MSILPSHTQGSESSSSSFSSQNPNLINHGFSTIHQHNQPQHSQVSSSTPHLSSLRISDHQ
PSGSIPNSGSMAEGGANSSGSSKKVIGFEGSNGKKTSPNHNSSNSRVQAHSVVEGGVGSP
QFGGEIGSSPPNSRASGSARRRYQAVSGNHLLNFQYTPISRSQPRGPPPKKPQKIKPYNK
DLFLQANYKFVVLDSGNYTVESMDPDKTLQWEDIICLRYSTPHPIQCPICLDSPLCPQIT
ACGHIFCFPCILQYLFMGEENHKAECWRKCPLCFMMISSRDLYTIYIENVREHNVGDVLD
FMLLSRGKNSFSLHEKLQGGESTKSCDSFSKFILTLDVDLSVREAISELDNWIARADSGL
VDDLEKIPYVCAAMEHLKQRKKYWNARRRLGGSKSCENNDGDTVDDLIPSCKDDEIGNGT
LSPAANDANKGTSHVMTDVVHGGVCLVQSSDTDESVEGHDVSLSSSYDESKTLRTNASLD
TKEKELYNFYQAIDGQPIILHPVNLKCLLHHYGSYDLLPARLSGKILQLESMTQSEATRR
RYRYLSHFPLTTTFQLCEIDFKDILPAEALSPFMDELKKREKQRKQLARKEHQDKIKAEA
VAAYSLPFPYNTMQSSCDTPTFSMDDFEALGSPVTTVASSPPVQGRQLFSNVARLGFAAG
CDSPSLNIPETTTEASIGRTSSSYASNGSTNQGACSFANVISREKSSESVTRKANEAGKK
GKKPSRVLLSTAGGRRY
>Sgl31852 E3_adaptor/Cullin_RING/SCF/F-box 12.2 0.0
MMNYFPEEVLEHIFDFVTANQDRNSVSLVCKTWFKVERESRSKVFIGNCYAISPERLISR
FPRLKSLTLKGKPHFADFNLVPYDWGAYVYPWIEALAKGCPSFEELKLKRMVVTDESLEL
LSKSCLHFKSLVLVSCEGFTTDGLAAIASNCRYLRELDLQENEVDDRKGHWLSCFPENST
SLVSLNFACLKGEVNLAALERLVSRSPNLKSLRLNRAVPFETLQKILSKAPQLSDLGTGS
FIHDPKSETFNNLKNVVSKCESIKSLSGFLEVAARCLPAIYPLCSKLTTLNLSYAPGICG
FELTQLILQCKKLQRLWILDSIGDKGLAVVADTCKELEELRVFPSDPFAPGDAAAVTEEG
LVAISCGCPKLNSVLYFCHQMTNAGLITVAKNCPNFTRFRLCILDPIKPDAVTGEPLDEG
FGAIVQSCKQLRRLSISGFLTDKVFLYIGMYAKQLEMLSVAFAGDSDDAMINVLSGCKKL
RKLEIRDCPFGNLALLTDMGKYETMRSLWMSSCQVTLGACKLLAREMPQLNVEIIDENEQ
GDFNLDDDRQKVEKMYLYRTLVGPRKDAPEFVWTL
>Sgl31878 E3_adaptor/Cullin_RING/SCF/F-box 15.3 0.0
MESNCCIFPDDLVEEILSRLPVKDLLRARCVSKRWSGLIDDVSFVKKHYQVQYSVPRLDE
NMTYFVDHFNRQDLYSVEFQLLSILHQGDAALPLTVDLTADLRRDSNAALPFGRDQYYQC
VGCVNGIICLFCESRNTLQAEDCFFALWNPATREFKTLPYPNDPCPTNYCQFQTDGFGFD
PSSSDFKILAGYIDRNDPYSLEHYQMLYSLKSNSWKWISNPPDPAHDVLPQGYFDRYLNG
VCYWVTGLHEEASGCPTNSVIVSFNFIAEVFKVSELPPDALSLVSESGGPYDQKLMLYKE
RLALAMSFKVREEASYDIHLWGATQLDDYGVPLSWQRLFTIRPTPAKFGLYADTMLMNGD
FQLVCNYGDGDSDTESYLYIHSSGELKKFDIWWKAWFRYVESLFPLSCKRQLVQT
>Sgl31903 E3_activity/RING/RING 30.4 10.5
MEFYSYPSQQIATSSSILCNLGEKIRGTLSFALSATLGSLFSAIFTFCFALVGTLLGAMT
GALIGQETESGFVRGAAIGAISGAVFSIEVFESSVVLWRSDESGIGCLLYLIDVIASLLS
GRLVRERIGPAMLSAVQSQMGAVETNFEDVTNIFDTSEVKGLSGDLVDKIPKIKITNKNN
IDASGERVSCSVCLQDFQIGETVRSLPHCHHMFHLPCIDKWLLKHGSCPMCRRDM
>Sgl31935 E3_adaptor/Cullin_RING/SCF/F-box 19.4 0.0
MSDLPFEIVRDILLNLPAKSLLRFKSVCKLWYEMINDPNFMKLHYEQSNLHIVFRNPTFH
ICDFDTFDNAVELDYPFKYLDDGYDKDSFLKGVHEWGSSCGLFCFTMDYCCPYTIILYNP
TTRTHKTLPFLAIEPPFHADRLNYLGFGYDHVSDDYKCVRILQDDEGSFSSQVMVYSLRT
DSWRRGAQDVPHFFQCHYEYYIDFKGILHWSAEGDNRTLPPIVAFNLSDETFSSVSLPNY
DTEVYTFSHIGVLDDCLCLMLNDLHHCDVWIMKEYSVTASWTRLFRLANKLNNFDLSPIS
FINRRKQLLVSYSSFKVFTVDLETLNITDFKLPGYRRIWTAYVCPENLLMFKDAENGLGG
IRQVWKKSVKRQRVMRLANRSLQQFASMLEEYEQPHSSNAGSLS
>Sgl31936 E3_adaptor/Cullin_RING/SCF/F-box 19.5 0.0
MSELPIEIVRDILLNLPAKSLLRFKSVCKLWYEMINSPNFMKLHFEQSNLHIVFRNPTFH
MCDFDTFDNVVELDYPFKYLDNDYNKDSYHKADKGVYEWGSCRGLFCFTTGYCQPHTIFL
YNPTTRTHKTLPFLAIEPPFHADRMNFLGFGYDSVSDDYKCVRILQHDHDDNDYDYKCVR
ILPHIDDDDDDDNEEEVEYFCPSQVMVYSLRADSWRQGAQDIPYYFRCQNEYYIDFKGIL
HWSAEDDNRRLLPIVAFNLSDETFSSVSLPDYETETFTFAHIGVLDDCLCLMLNDLGHCD
VWIMKEYGVLASWTRLFRFAKEQTSFHFSPISFINRRKQLLVTYSSFKVFTVDLETLKIT
DFKLPGYRRIWNAYVCPENLLMFKDAENGLGGIRKKNAKHRRLMRLA
>Sgl32010 UBD/UBC-like/UBD_UBC 113.3 0.0
MVGIPSNELLFHCREAESLKKPFTPLREVHVQVTHSMPPEKIEIFKSLEGWAEQNLLGPS
ETPYDGGVFQLAFAVPEQYPLQPPQVRFLTKIFHPNVHFKTGEVCLDILKNAWSPAWTLQ
SVCRAIIALMAHPEPDSPLNCDSGNLLRSGDLRGFQSMAKMYTRLAAMPKKG
>Sgl32301 DUB/USP 146.5 0.4
MICRCSSFDATGSQQYAGLLGRGTPWMKSIACSMPRSDWSSLCSSSGKTSANSVSNDKRC
SLVGAMVGCLENYVPIEHLTSKLDALNARLDARPLSFSRPSDDSATKYTKLDERNNKLED
FTGICSPEEYLEWERQVDKLADIKELDDSQTFKIGFLRLTKHACLWFDGVKAKRKRQDKP
KINTWSQLRKKMRDKYVPYDFDQQNYLRLTSLFKGPMTVIEYIAEFERLTLLIEGALKSF
TKVESIEVTENFLCDNCKEKVKVEKQLILDQAPSVVGLHLKRFKSDGIYVEKIDKKVEFP
LELDLGPYTKGSNDGHEDLKYELFAVVVHVGFSSTSGHYFCYIRTSPEKWYRFDDSKVTM
VEEETVLDQHAYTILTA
>Sgl32514 E3_activity/RING/U-box 117.6 0.3
MEESLITTTSTTPSTTTEVKETRDPPSISMDGELAQNIHLVISDIGKISTNGGFCDLFKK
DCNDLGRRISLLSYLVDEICDSSSPSSSSSQSHSDNNNDEDYDNDSSSNSCFVDLFVALQ
DSKRLLLAASSFDPNEDGATKRVSFQFQCVTWKLEKALGNIPYEQFGISEEVQEQVELVR
TQLKRATERYGPLNSSKIIRAASQPLLNELELLQSGNKGFGCLHLDNTGNIDHEVRRKVK
TSRSGNSSTSDSHDVSERVELSSVAVPECVSSSVEEEDGCSGETEEESMKPDSVSIPEDF
LCPISLEIMRDPVIVSTGQTYERSYIQRWIDSGNMSCPKTQQKLQHFTLTPNYVLRSLIY
QWCAKNNIEQPTALMTGKIKKSDGTFRDVSGDIAAIQALVRKLSSRAVEDRRTSVAEIRS
LSKRSTDNRILIAEAGAIPVLVNLLTSDDELTQENAVTSILNLSIYEHNKELIMLAGAIP
SIVQVLRNGSMEARENAAATLFSLSLADENKIIIGASGAISALVELLQSGSLEERKMLPQ
HFLTCAYIRVTRAGQSELVSLQH
>Sgl32578 ULD/UDP/UBQ/UBQ_Other 24.7 0.0
MAGEKESPSPLLPETEEEITLIVKWSGKEYTVRVCGDDTVAELKRRICEATNVLPKRQKL
LYPKVVGPKLSDDSTLLSNLPLKSSVKMTMIGTVEDDLIIDPIDSPEILDDFELGQDEAV
DIKDKEVNKQKLRRRIDQYKIEVRNPCRTGKKLLVLDIDYTLFDHRSPAENPLQLMRPYL
HEFLTAAYAEYDIMICMKWVELKMGQLGVLNNPNYKITALLDHLAMITVQSESRGIFDCK
PLGLIWEQFPEFYSSRNTIMFDDLRRNFVMNPQNGLAIRPFRKAHANRESDRELVKLTQY
LLSVAELDDLSILDHRSWESYMEDNSKRRRRA
>Sgl32742 E3_activity/RING/RING 32.5 6.6
MKLFFLITTTSTTTFLLFTSSVTCRPLISPSPENPPPSNFSPFKPTIAVVVAVITTLFSV
TFLLLMYIKHCKQQQQSLSSNSQQSAYYQYHTTRFPFSGRKNSGIDPVIIESLPVFRFKY
LRGEKNGLECAVCLNRFEPEEILRLLPKCKHAFHVECVDTWLDAHSTCPLCRFRVDPEDV
LLIDRVIDHADLGLGLGLPESTNRISGRHSSAGERGNNNKTNNYKNINQNKNNDETTSYR
RSLDGSIAAVERRKDGMLLTVDKERRIEHKIVIEVVENQKLRGSSGGGGVHERWSDVQPY
DLLYLRSEMLMNEGRRSSASKRVQGSNNGVKMQGINEGGGNGNGNGRNVINERSVSEITG
LSRYSSRNTGGGGNEERERERHNGAVARWMAWISQSRTAGRLGA
>Sgl32771 E3_activity/RING/RING 10.8 13.6
MGDHLALLVNRLLTESTIHAAIESRNRAKELEEGIDVEFLKQKEDNGDGDLSSPRKLVEC
RICQDEDFDSNLETPCSCCGSLKYAHRRCVQRWCNEKGDTMCEICHQPFKPGYSAPPPLF
QYGHIRMNFRGNWQISRRELTQSQLMMEPVSTNHALLNSDLEEPSSRSFICRLTVAVIFI
GLLILRHTLPIMVGGSNELVLPLFILAVLRVAGILLLVYVTIMAISGLRRQRNQDETTNV
PETSSEEEEEENEHLESQQPSHVIQIS
>Sgl32801 E3_activity/RING/RING 35.1 7.3
MYSSIPQEIITSRHLHYSRRLLLETHSHSPPLPTPMIEAPTPTYQVLDPNSSHHKAGFDA
NIIMILAVLVSALICSLCINTLIRCVIKCSSILRGEPNYYLNMISDHDNDKKTKIGGVDK
RALKTFPVVKFLKDVKIQGLGTDCVICLSEFKVDEKIRILPKCNHGFHVKCIDQWLSSHS
SCPTCRQSLLETCQKIIGCGEDHVTSLSSSSSSSSTTTTISFSSTEEMITVSIDPLQRED
LIRNYRGD
>Sgl32830 UBD/UBC-like/UBD_UBC 61.8 0.0
MLGAGLQFNRNGSDDRFYVPAKGRRNYNQNQNQNQNQNQRNPQFQGTQSDVVSGGVGGSR
SRDWAVVPEPGNGPGEPSRPAAPPAFKQLPLPLSNVERFLESITPSVNAQYLSKTTMRGL
KTCDVEFQPYFMLSDLWDSFKEWSAYGAGVPLVLNGSNSVVQYYVPYLSGIQIYVDQSKS
PAKTRRTSEDSDGDLYSKGSSSDGSSDSERERSLAYSRGQRNPYNHPNDISVNLGRLLLR
DQHIVSQEGFSSDEGESSTGQGCLLFEFFEHDAPYGREPLADKIADLAQRFPSLKSLRSC
DVLPSSWVSVAWYPIYRIPMGPTLKDLDACFLTYHSLHTPIGDAVSSQPPVVIYPSEIDG
IPRISLPVFGLFTYKFRGTLWASSNGSDRQLVNSLSEATDRWLTLLQLNLLFSLSENHYG
DCLHKKCGDFDITYPFYIIGLQKPYCGYPGFEVNCTDQRFPVLNISGNNYVIKNISYDLQ
QFEVVNSVFDDDGGGGAICFDSLRNVSWERDIFQFAGHHDQVFLFRDCPNKVIQENKLNR
VKCGGIAVDGKDPKLKNIEKECHNLNVITLPYRDEGVEFVDNNITHTLERGMLLNWRAYN
CTACAETGGQCGFDMVNNQFNCYCPDRTHALRCNQKHMTLSKFGGCKKVVTLPYEGSQVT
DIDGVLRQGIGLNWIPSNCNECSDSGGRCGYDEHSSKMLCFCPHGAYSHRCPTQSTSGLF
NCAICQVDLAASEGISVHAGSLFSTSAKPWQGPFLCADCRNKKEAMEGKCSSDKWRRRRT
VAATHAGDSQLLPPMTVALSWCGVLSLLFSCSRINIDKNVKADSEKFQKSMNLEHEPVEK
VKKSLPRAYSRIDSEKDLTSQMGTSLVTDQPLSSDSSLNNGAYFVYLTGFTQYKSYFVGP
YKGGAWKIMVELPDAYPYKSPSIGFVNKIFHPNVDEMSSSVCLYVINQTWIPMFDLVNVF
DVFLPQLLLYPNSSDPLNGEAAALMMRDKVAYEQRVKGSGVTVQWLKFDNSYFKVLHLLP
LNPKLNLLFSLSENHYGDCLHKKCGDFDITYPFYIIGLQKPYCGYPGFEVNCTDQRFPVL
NISGNNYVIKNISYDLQQFEVVNSVFDDDGGGGGGAICFDSLRNVSWERDIFQFAGHHGQ
VFLFRECPNKVIQENKLNRVKCGGIAVDGKDPKLKNIEKDCHNLNVITLPYRDEGVEFVE
NNITHTLERGMLLNWRAYNCTACVETGGQCGFDVVNNQFNCYCRDRTHPLQCTQKKLRLP
AILVGTGSASLGIVFVVAVIIFAKRRQRAIRFTIEWKKAAKRNQNVEAFMQNYGSLAPKR
YTHAEIRKMTNNFKEKLGEGGYGVVYKGQLLQHSHFVAVKKLKKLKGDVDDFLNEVVSIS
RTNHVNIVSLLGFCFEGKKRALVYDFMPNGSLEKFINSEGSGCQSLPSKTLFEIALGIAK
GLDYLHRGCNMRILHFDIKPHNILLDKELRPKISDFGLARLCSTDDSLLSLTEARGTIGY
IAPEVFCRNFGGVSHKSDVYSYGMMLLDMVCGRKNIAVVRPQQSSEEYFPDWIYHQLEFQ
EEIDEIRNNQEQELRRKMILVGLWCIQSYPSNRPPMNRVIEMLEDIQVNDDDTDLQDAKV
IETRCYFVGNVGGGGPQGFGFLFENRKLPLILGLSLGGGVFVLLAFVAIWHRKKLKFRRP
KVETRSVSLDHSTSDLERGNMYFGVPLFSYSELLEATENFNQSKELGDGGFGTVYYGKLK
DGREVAVKRLYEKSFRRVEQFMNEVRILTCLRHQNLVSLYGCTSQYSKELLLVYEYVENG
TVADHLFGDKGKPGSLTWPIRLRIAIETASALSYLHASDIIHRDVKTSNILVDSSFRVRV
ADFGLSRLFPTDVTHVSTAPQGTPGYVDPEYHQCYQLTDKSDVYSFGVVLIELISSLPAI
DMERHRHEINLSNYAINRIQQCAFNELVDPQLGSESDSKVRKMTTMVAELAFQCLQHEKE
FRPTMDEVLETLTRIESTDIDSLQTDETSKNTDEVVKLQNSQAPPSPVVENDHTQLLNHN
RLHPPSPISVMDKWESRSTMHSNSKDLCTKLTDR
>Sgl32842 E3_activity/RING/RING 29.6 13.3
MATPLTGIGHREGGGVAIMVNAVDPSPPSSSSSSSKASLKNSAQKSPILIFLFFHKAIKA
ELEGLHRAAIDFATNHGSDIKPLLERYHFLRSIYKHHCNAEDEVIFPALDIRVKNVARTY
SLEHEGESVLFDELFELLNRKVRDEEAYRRELASRTGALQTSISQHMSKEEEQVFPLLIE
KFSFEEQASLVWRFLCSIPVNMMVEFLPWLSSSVSIEESQDMRKCLRKIIPNEVLLHEVI
FTWMDGPKMDKFRTSCGATLQCCIDSKACASVGQIKGASCACESSHTGKRKRVKLSNSTA
DSDLSYPIDEIILWHKAINRELIEIAESARKMQLNDEFSDLSAFNERLHFITEVCIFHSI
AEDKVIFPAIDAELSFAQEHAEEESEFEKIRCLIENIKLANAESSLGELYSRLCSYADQI
LDTIQKHFHNEEIQVLPLARKLFTLQRQRELLYQSLCVMPLKLIERVLPWLVGSLGEEEA
KCFLKNMHMAAPDADVALVTLFSGWACKGSKMNVCLSSSAIGCCPARLPNGEGNEHLVSK
CTPCLANGDKAAIGHHDEESQLSKRCKIASTEKVSNLEEKRGDDSQKLSCGTLSCCVPGL
GVNNGNLVVSSLTAAKSLRSLSLSPTAPSLNSSLFNWETEISISDTGSTTRPIDNIFKFH
KAIRKDLEYLDAESGKLSECDEAFLRQFSGRFRLLWGLYKAHSNAEDDIVFPALESKEAL
HNVSHSYTLDHKQEEMLFEDISSALSELSQLRGAVSRSSAAVAPPGNDSDAGDSSAHLRK
YQELATKLQGMCKSIRVTLDQHVFREELELWPLFDKHFSVEDQDKIVGRIIGTTGAEVLQ
SMLPWVTSALTQEEQNKMMDTWKNATKNTMFSEWLNEWWERAAPSQPCSASEISLTQGHD
VCDALDSSDQTFKPGWKDIFRMNQNELESEIRKVSRDSSLDPRRKAYLIQNLMTSRWIAA
QQKSPHGGTGESSNGDDLLVLSYRDPEKKIFGCEHYKRNCKLRAACCGKFFTCRFCHDKV
SDHSMDRKATTEMMCMQCCKVQPVGAVCSTPSCNGLSMAQYYCNICKFFDDERSVYHCPF
CNLCRVGKGLGSDFFHCMTCNCCLSVKLVDHKCCEKGLETNCPICCDFLFTSSASVRALP
CGHFMHSACFQAYTCSNYICPICSKSLGDMAVYFGMLDALLASEQLPEEYRDRCQDILCN
DCGRKGTARFHWLYHKCGSCGSYNTRVIKMSPTDSNCSK
>Sgl32894 E3_adaptor/Cullin_RING/DCX/DWD 18.4 1.1
MDKKFDNSIVAHVKDFRSFSMIEVQDWISHKWLSLAPISVEKISNKSFMLFCSNEKDRDK
IMSFGLANFRGAMFIFKRWFRGASIRELNFDLSLMWIRVEGIPLHLNQFHVATTVLDRLG
SVSCFDRSSSLQGTTTMDNRSTGLNLLLDPHSFEPVDNSDILMSDSSEDEQLNDEEVNST
DESNNDNNNDDDSHGDPYGGSKRTRDSDSLDSDDSSDPSGDCGDYPSTRRKRAFHNQMLK
DEAQSYMKSHNQDSSGQRKRKARNSVDYVWYSKVRKILTEGSLTGLLPGLHGPSKGPTTA
RPYSILHQRTLLDMNLLPLSFPVQLPASTFPTTSMASFSDNDTEIPYSSSFGDHEVTLIP
SVAINILVPNSSECSKAPPNSPRESFSSDLPTMPLFDINQVWTNFMGSSSFSFPNPFDLT
NLTLSPTQRNILAENLVKYTQVAPRISDDDTFFSDLASDETITLDVIETPFVSPVSTHAA
SPPATSPTNHDTKTSLYKLGKVWSQFARTMSRSAPTHNKSPPPLSDEFVSDDEEENAVDV
VSVEVGNGLMTAEGAACLEKPVEVQGIFSKLGFSSSFGVDADDSWLQNYPNANVQNFPIL
LSDHGPVLLNTNPPQKPKKAPYKFEAWTLEFEEVHSLIKDNWAAPLQGSRLFQLQRRLEV
GLLHTRTWGLAFKKAHNICWDDIHASLSEAQGTINNTPAASMAISQIQSAQVDVNIKTAF
WKQRAKINWDLLGDQPTAYFYKNVKTKSLRNHISSVTDSTGTLCTTQDTLSDAFVNHYDS
LLHVNQITPQTQRLQQEWSEGLTPLSDEHLLMIRSPFTDDEIRAAFFSMKPLKSSGPDGV
APVFFQKSWNTVHTQVCDAVRGFFNGGKMLRETNSTFLTLIPKIKNPSNVADFRPISLCN
TTYKVISKCLVNRLKPILNDIVGEFQNAFIPGRLMGDSSLVAHELSHWIRKKKKGKLRAG
LLKIDLSKSYDRVSWEFVITIMKKLEFPQCWIGWIQECISTVSYIILVNRSPSNSFRPSR
GLRQGDPLSPYLFILVMDTLSKKLIKLHHEGLLKGIQIGRHAPAINHLFFADDATFCFHA
KLRTMAALNRTLHDFCIVSGEMINLVKFIIVFSPNTPLKYRKFLTRKLQIKEAENMGKYL
GNIMHVDGRSFVCFQPLVNKIQNTIASWNNATLSQCGKLILINTILIAFTSHILSMYLIP
RKISKAINSSLLRFWWQTSSAKKPIYWKKQSLLTAHKNNGGLGLRNVDTLNKCLLFKQAW
RLHSHPHILSARIFKGRYGMDPIKMAIAAKMPTTISWAGKCMVKASTLFVTGLNKRINSG
TATSITNDLWVNNSKVDFKVSERHQPNNPSKWGIRGYFWGIRGVVLGGGEGYCRPAERCL
LYSMKFWGHDLEALLIASSTIFNEIVVWKLIRQHGTLPITSAEQEHDVMRTLVDVHSQEC
LEYEAEIVSKLAGHQGSIFCLSWSDDGSKLVSVSDDRRGRNVYMQFSSHQELTTDQPQAR
KSDSKSDNGDAGGMYPLQATGNGAGA
>Sgl32933 E3_activity/RING/RING 17.9 4.5
MECLHRFCRECIDKSMRMGNNECPACRTHCASRRSLRDDQRFDQLIAVLYPDIRKFEEEV
MYELEDVDLQKICYEVPPKRKKKYFVLNDYFFAQIQESITQVLIKQSEALGKKRSSNKDA
AGPSVTRSQR
>Sgl33130 E3_activity/RING/RING 35.2 7.9
MSTSTVHPLMYQVQYARRLLLVQHSPVEQSPAVGGTAPTIAKNPIDPTEPYNGTNNGFDA
NVVMVLSVLLCALICSLGVNSIIKCALRCSNLMPASSNPPVGAEKGIKKKALKSFSVVNY
SPKLKLPGVGTECVICLSEFGEGERLRLLPKCHHGFHIRCIDKWLKTHSSCPTCRHCLIE
TCHKIIIVGCGQASSSSSSSSSTSLQTPLPTQTTVLNIAPLEREDFVSNY
>Sgl33131 E3_adaptor/Cullin_RING/DCX/DWD 133.2 28.2
MKCEVERAFIGAGCNRIVNNVSWGASNFTAFGAFNAVAIFCPQKAQILTTLPGHKAAVNC
TYWLPTSKFAFRAQQSKHHYLLSGDADGITMLWELSLTDEKWRHVLTVPQPHKKGVTCIS
GIMFSATEAIFASTSSDGTVNIWEIILPVIAGGECKLSCLDSLAVGSKTMVALAIAELPD
NTGHVVLAMGGLDNNIHLYCGERTGKFVRACELKGHSDWIRSLDFSLPIRQNEARDGLLL
VSSSQDKSIRIWKLVLCETSGNSERKDIIGLASYIEGPIFICGSSTYQISLESLLIGHED
WVYSVQWQPPSVASEGGGYIQPQSILSASMDKTMMIWKPERTSGIWMNVVTVGELSHCAL
GFYGGHWGPNGDSILAHGYGGSFHLWKNVGIHSEIWKPQKVPSGHFASVSDIAWAKSGKF
LLSVSHDQTTRIFAPWLSHMGDRCSWHEIARPQVHGHDFNCVTLIQGKGNHRFVSGADEK
VARVFEAPLSFLKSLNCAVAQDSDIQEDIQLDVQILGANMSALGLSQKPIYAHAAQDTAE
RPGPGSEAVDTLETVPEAVPVTLTEAPIEEQLAWHTLWPETHKLYGHGNELFSLCCDHEG
KLVASSCKAQTVSVAEIWLWQVGSWKAVGRLQSHSLTVTQMEFSYDDSLLLSVSRDRHFS
VFSIKRKDVDEISYELVVRQEAHKRIIWACSWNPFGHQFATGSRDKTVKLWTVVNKSSVK
LLLTLPTFQCSVTALSWLGTNRQTNQGLLAVGLENGLIELWGLSATRTEDECMTTSGFLA
NVVAKFDPFMCHASTVQRLAWRNSEKEEDCQYSQLASCGADNCVRVFDVDVKEF
>Sgl33153 E3_activity/RING/RING 35.2 7.9
MSTSRVQPLMYQVQYARRLLLVQHNPVEQSPAVGGTAPTIAKNPIDPTEPYNGTNNGFDA
NVVMVLSVLLCALICSLGVNSIIKCALRCSNLMPASSNPPVGAEKGIKKKALKSFSVVNY
SPKLKLPGVGTECVICLSEFGEGERLRLLPKCHHGFHIRCIDKWLKTHSSCPTCRHCLIE
TCHKIIIVGCGQASSSSSLQTPLPTQTTVLNIAPLEREDFVSNY
>Sgl33203 E3_adaptor/Cullin_RING/SCF/F-box 13.6 0.1
MEEVEAIEILEQQHLPHDLVAQHILTRLPIKSLLKFKCVAKQWYSTISSYHFAHTHFKLC
PFNHPNSPTQFLFVQNRSNYYLFAYDNGNEIGATVDKNLVNLRINFHDDELVLVGSCNGL
VCLASYCGFYFILWNPITGQFCKYLDHELLVDFSSKFRVSWGFGYVSCVDDYRIVRILES
NTTVEIRVHVFSLRTKKWSRIDDEVYQDIFSLRTKNHVSIGTDSFRVPVSFYSRQGVLVN
ETLYWIVSKTNDWGRKVVSFDLVHEIFDTVSDLSLVSNDAFKDKFLCVMGGCLSKFGVSI
HDDVYIGILKGPGKVESIRLSKYLRLRSCQSFVGFTRSGGFFILLEDSTIGVVNPTSQPM
KYKYTPLVTFESLGKTRVANYAPSLISPYPVA
>Sgl33232 E3_adaptor/Cullin_RING/DCX/DWD 59.9 10.6
MSTNLLPLNCFLVIQSSRMQLLSIYELVPAEKNMCAVNMLHPSVKGSLLLSDPAIGTSGY
CSGQHNAWSSYYFRNHWNDEFKDKVSLELTEETLQSMEVGMAFRDYSGRISSMDFHRNSS
YLVTASDDESIRLYDVANATCLKTINSKKYGVDLVCFTSHPTTVIYSSKNGWDESLRLLS
LNDNKYLRYFKGHHDRVVSLSLCARNELFISGSLDRTVLLWDQRAEKCQGLLRVQGRPAT
VYDDQGLVFAIAFGGYIRMFDARKYEKGPFDIYPVGGDFSDANVVKFSSDGRLLLLTTTN
GFIHVLDSFRGTLLCSFNVKPVSTTSTLEASFSPEGMFVISGSGDGSVYAWSVRSGKEVA
SWISTEKEPPVIKWAPGNIMFATGSSELSFWVPDLSKLGTYAARKLT
>Sgl33267 UBD/Alpha-Helix/UIM 28.5 12.1
MVLEATMICIDNSEWMRNGDYSPSRFQALSDAVNLICGAKTQSNPENTVGILTMAGKGVR
VLVTPTSDLGKILACMHGLDIGGEMNLAAGIQVAQLALKHRQNKKQQQRIIVFAGSPVKY
EKKVLEMIGKKLKKNSVALDVVDFGEDEEGKSEKLEALVSAVNNNETSHIVHVPPGANAL
SDVLISTPIFTGGDGEGGSGFAAAAAAAAAGGVSGFDFGVDPNLDPELALALRVSMEEER
ARQEAAAKRAAEEGGPSGEKGEEQSSQDVAMGESSNAANSEADKKTDLTEDDENALLQQA
LAMSMDDPASTTTVRDTDMADAAGDDQDLQLALQLSVEENAKESTSQSGQADMSNLLADQ
SFVSSILASLPGVDPNDPSVKDLLASMHNQSEKKDEDKPPSEEEKK
>Sgl33287 UBD/UBC-like/UBD_UBC 233.3 0.1
MAMKRILKELQDIRRDPPTSCSAGPVSENLYQWQATLIGPADSPYAGGVFVLSIHFPSDY
PFKPPKVAFRTKVFHPNINNNGNICLDILRDQWSPALTISKVLLSICSLLTDPNPDDPLV
PEIAHMYKKDRVKYEATAQSWTLKYAMN
>Sgl33293 E3_adaptor/Cullin_RING/SCF/F-box 13 2.4
MGKVSPKEKESKTPKLKRRTRTSNNKYLRPGALAQLRYSKASSTKSCTDLGKKRVVLLDS
KKAVTNDLVNEQQPTPVQETPMVSPQKFGFSSVLSPLEFVRQQSLPKTPKTPRPEDSVFD
SRLEALPIDLLVKVLCHLHHDQLKAVFHVSQRVRAGVIIARQYHFNYTTPDRSRQEMLKT
MTPLATEQWPFVSKGESKGFWLPSPHTPKAPRHGPRPPSRLKYTEMRQVAAALFQEASLP
SRCRIPSVLSKPPCKNRVLLYEDELCQAVAQNKLR
>Sgl33340 E3_adaptor/Cullin_RING/SCF/F-box 18.1 0.1
MELQEELLMEILAQLPVKSLIRFTCVCKYWHSIITSSEFATKHYETRLKLNEYNYDSILT
EFSPARSMSIFSYQDLTFQTAFKFRPAVAYDPPKFGISHREITCYHRIYGPCNGLFLLQF
MKHSCDLNLEPVWLLWNPAIRDVFRVPSLQGFGSSFVGFGFDDVNNDYKIVFFAFDVNLN
CKSSVLLYSLAANSWRQLDVTLDIGYGGQPNPAGPAGYSSNNGRKHHWMMSEYSRRGRGL
RQTRCTSFLLSFDFVDEVFVQTLMPFDEEHEHPCKFLDQGSNNVYPTICCVVDEAYATTK
SMHIWVLNNYGPTGSWSKLRSLTIPKVIANSSLLLWKNNNAIVFANRGDQQALTLYDLIT
KQMTSLKFRGDQTILAYTESLVSVAKFVRPPPPPPPPHYSLVAASLQDHQMNSVPQHRLL
SPEEYSSLEAEFQQLLQENYGNDDDDSSTDSAFLMPLAPPYGNHNAIFVDYETDLKFLHY
RGNEIRRLLLLPYCLREVNQPMISNPCTF
>Sgl33380 UBD/Alpha-Helix/UIM 15.5 1.1
MEDVLSPTDQQSMVSSFLEIAVGQTADTARQFLQATSWKLEEAIQLFYVGNESGAIASSS
FLPTEEIANPTPVANKSFSGSDEALARELSGLNGGDDDVRAPLPVIREALYDDALLYGGS
RIGYPSHVPGSVVAFRNFEEEMKHPAVWESEQGGSSSTESSRDNLAALYRPPFDLMHQGP
FEKAKLAASAEDKWLLANLQSPTEFSSHMLNRDTWANEAVAQTIKTNFIFWQVYDDTSEG
KKVCTYYKIESVPVVLVIDPVTGQKMRAWSGMVHPDRLLEDVMPFLDGGPRNHHSSLSHK
RPRESSNTPVPKSPVETNEEDEELQQALAASMENMTHPNQESAEDKGAGIVSKEEETCST
KKPVYLPLPEEPKGDRSLLCRVGFRLPDGRRIQRNFLRTDPVQLLWSFCSAQLGEAETRP
FRLTHAIPGATKTLDYESNLTFEESGLSNSMISITWE
>Sgl33389 E3_activity/RING/RING 16.8 10.3
MEPKETCAICLRTINPSQRRALFTAECSHTFHFLCVASIVHHGNHNCPTCHFTWTNLPSQ
TTPKQCCRTPALTLLSFADDEPLPSPQQENWLRPTANYRPGFSCCALSPVATSSTTSPST
WPQNKVNVTVKALPEHLTLCKSDRNNDSFPILDGIQAPPLSPEVSDRQTDHAPIDLIVVL
DGSRAEERHSSIILLSDGQDNKDGHNPVFLQSLHLLPHCLRANDITANAPLTDVFPVHTF
GFGADHDATALHAIADGSGGTFSYVESIEIIQDAFARCIDC
>Sgl33421 E3_activity/RING/RING 26.4 5.7
MESKETCAICLGTLNVGGGQALFTAECSHSFHFSCIASNVQHGNHLCPTCRATWVNLPSQ
FTPTDDAPYKHSAPAPAPLILPPFPDYETLPPPSPVAPTSLPLHSFADDETLPPPSPVAP
TTFSTPQNDDRVTVKALPEYPALSNSYQSNSFPVLVAIQAPPLSPEAFDRPTYRASLDLV
AVLDVSESMDGDKIMLLKQAVGFVADNLGPSDRLSVITFSTSARRVTPLRRMTDAGRSDT
IRAVNKLRAKGTTNIVGGLKLGVEVLMQRREKNPVSSIILLSDGQDNQISYHSSFLHSLC
DLPPCIRSNYVHLATNVLRTDVVPVYTFGFGVDHDATALHAIADGSGGTFSYIESIEIIQ
DAFARCIGGLLSVVSQELEIHLNSASQGVQIQSISSGRYRNNIDSGGLHGMVYVGEVFAE
EKKKFLAYLSLPPADAETLKMQLLEVKCSYKDPLSNQNLMSENVSVEIRRPITEDLTEED
KQVCLELDRERNRVSIAEGIEEAQAMAERGELSRARATLEQWSRELRQSASAQAGDALCG
RLEREMDEIHRRMSSRLDYEEGGRAYTLSIQSAHMNQRASTHFYTCPLPRQRQDDNERKD
AVTQPMDRWSSPIDEPEYQTSFMSRMVRKSQELLFPRKKDEKSAASSSSNSMN
>Sgl33422 E3_activity/RING/RING 25 5.2
MDSKEKCAICLAALNATQGQALFTAECSHIFHFTCVASNVQHGNYICPTCRATWVNLPSQ
FTPTYVPNLNNPTFTPLLFADDETLPSPSPSPVAPSSTPQYDDSMKVKALPEYPALSKSY
HSNSFPVLISIQAPALPPEASDRPSDRAPIDLIAVLDVSGSMNGDKIRLLKQAVRFVVDN
LGPTDRLSIITFSTTAWRVTPLRRMTEAGKSGTIRAVNNLRADGSTNIIAGLKLAVQVLI
QRRENNPVSSIILLSDGQDNQNGYGSSFLHSLCDLPPCIRANDVHLPTNTPQTDAVPVYT
FGFGADHDATALHAIADGSGGTFSYIESIEIIQDAFARCIGGLLSVVSQELEIHLSSVSQ
VVQIGSISSGRYRNNIDSGGLHGIIYVGEVYAEEEKKFLAYLSVPPADTETSHTQLLEVK
CSYKDPLSNQIIISEIVCVKIRRPLAEDLSEEDRKVSLVVDREINRVSIAEWITKAQVMA
ERGDLSSARAMLQQRRMELMQSASAQAGDPLCGQLVSEMSDIQQRMSSRSEYERGGRAYT
YSRTSAHMSQRASTQAVRSHQMPTPIVRKSAPVGGAVTAPIVSSSPPPGDQMDYQTSSMR
RMVQKSQLSIKPENQK
>Sgl33425 E3_activity/RING/RING 40.6 3.6
MDVQSITLDEEQELLSYLSNDIGVEVTSFAFEKASASASASASVTKPVDDFFSVWLRYQD
SRRYPNERNAWFEFRKDNQDVLGLVLNLFDDGLEFTVDANAYDCVIDVVQESCDVLLQQV
SEVGRKSLAMIVMIKVDAAEDVDDVAAVDDEVNNNDMDYSSYEDVESDDVEVMATMSSTE
VKDYLSSNGGVRFLRSDQANTNTMVECCSICLEEFDKRGDDVAVLPCSHVLHTDCLVPWI
AKGKDTCPMCRFNLLN
>Sgl33445 ULD/UDP/UBQ/UBQ_Other 43 0.0
MPEEELVEVKFRLYDGSDIGPFWYAPSSTVGHLKEKIVTEWPKDKKLTPKAVNDVKIINA
GKILENSKTVGQCQMPFGELQSGAITMHVVVQPTVAKTKAEKKVDEAEKKSICSCSIL
>Sgl33479 UBD/Alpha-Helix/UBA 23.2 1.0
MEDEEMQKLLNMGFSKELASQALAATGGQSTLKATEWLLSHPHTLSKPSIPNFQSQSQSQ
SQSKLNKFFPFNSSKDSKQPSSQIPETPQIPHPNKRPKPGPKPVPHEPLSERMRPRVVDE
VVGQDHIVGPNSFLSSAIKCNRLPSIVLWGPPGTGKTSIAKAIVNSCSNYYKLVSLSAVY
SGVKDVREAVDGARKLNEFGGGKRSVLFVDEVHRFNKSQQDSFLPVIEDGSIVFIGATTE
NPSFHLVTPLLSRCRVLTLSPLCPLGIGKLLRKAVDDSEKGVSLSVGRKVEVEHEVTEML
SSQCDGDARVALNALEVCATTALGRVQGKGQSLEGSKSGSGSGSGSESCLNDGVLMVKVE
DVKEVLQCKHVAYDRAGEEHYNLISALIKSMRGSDANAAIYWLARMLEGGEQPLYIARRL
VVFASEDVGLADPNALLQAVACHQACHFVGMPECRLNLSQCVAYLALAPKSVAVYKALNE
AMKVVKDSVGGNPGVPLHLRNAPTKLMGELGYGKGYIYTPDNPTAEQSFLPPSLQGRKFL
EWPPSDT
>Sgl33515 E3_adaptor/Cullin_RING/DCX/DWD 87.4 16.8
MGGVEDGQPPSKRLRLSCAGSSSVSSGVRAEEPVAAGSLRDLMARPRQCQGEEEVIGSRR
IIKKLEFVRLIAGALYALGYERSGASLEEESGVPLHSSAIKLLMQHVLDGDWDECATILQ
DICLEDETLMKLAKFLILEQKFFELLDSGKTMDALTTLRTEISPLQIKTNRVHELSICIL
HHPLSQNGTAHKDSVKPRSRTEVLFELQKLLPPKIMVPARRLEYLVEQALNLQRETCLFH
NSSDFDMSLYADHHCGRDNIPRYTLQVLQDHKDEVWFLQFSHDGKYLASASNDRSTIIWE
VSVDGEVVFKHRLCGHQKPVSQIAWSPDDQQILTCGTEETVRRWDVFSGECLQVYEKAGY
LAISCAWSPDGESVFAGFSDKSLCMWDLNGKELECWKGQKTLKISDLAVTLDGKQIISIC
RETAILLLDRETKVEKLIEEDQAITSFSLSNDGKFLLVNLINEEIHLWTIDGDIKLVAKY
NGHKRSRFLVRSCFGGLEQSFIASGSEDSQVYIWGRSSGQLVDILPGHSGVVNCVSWNPV
DPHMLATASDDRTIRIWGLGGANMRRRVCQSNGTHHSKSNGTHHSL
>Sgl33542 E3_adaptor/Cullin_RING/SCF/F-box 19.1 0.1
MNSLCYVYLPENIIFEILLRLPTKTLIQCKAVCKQWKSIITTSFFARSQLRFLKQQFILP
PYYLLCSYDWSFALNLIHNSRHYRQCITSKELENQVLPLSSKSFELTFDKDILLSTCNGI
MCFYLKEKISLCLWNPTIDETRFVALPYESYWIRKFYFVGFGYASSIDDYKIVLAAKYAC
HTSNTINDRRSLGVYSLRRNEWRELDFDYYKSIAPEIYSGLGWRSGRQPSSNGIRMESIV
VNDALHWVIDSYICNKNMKFFLYKFDLVNEYFEKVDVDLNKIISNIIVDDDNRLGPRQIE
IGVTENRLVIYQLYSEFRHSNPSNEFLVKRDVVKAWEMAEQYDYNSWKIKFRYVGDWDDI
RDNHDLVRITGNGNVLIIGGTYAEYESRLSFDQNSHKQRAQDVDFYAKHYVPSLVSPNNF
>Sgl33636 E3_adaptor/Cullin_RING/SCF/SKP1 88.7 0.7
MASNKKITLKSSDGETFEVDEVVALESQTIKHMVEDDCADNVIPLPNVTSKILSKVIEYC
KKHVDSPKSSENNDRQVDEELKNWDADFVKVDQATLFDLILAANYLNIKSLLDLTCQTVA
DMIKGKTPEEIRKTFNIKNDFTPEEEEETESHLYLLSTYIYTLQLWDKDGIVNNSVFWRV
LAAAAGGSPLSHLSLHAD
>Sgl33639 E3_activity/RING/RING 32 13.7
MGIRRNVKEVQRLSFTSDDDVCCVCLSSLSKEGEDIKVLPCCHHFHSKCVDKWFKARRKT
CPICRFIVEEERKEEELSREMVIWFVAHKPRSSVVVYKTIAITRGKKTSFSPLDL
>Sgl33680 E3_activity/RING/U-box 78.7 0.0
MDDTTMDTMMQQQQQQLHLHEKVHVVLSKEMQQEDGLSTLNWILNYWSSQSSHHLLSIVI
LFITSSSSSSSSLDLVDTPFGKLPATSVNDNMLQIISKCEQQKTDKLLSNYIAFCGKVRT
EVHKINNSNDQPIQKTLVDLIIQKRITKLVMGMTFMRSSSGRTKSAISESVYIHRTKPDF
CELFILCKGKLVMVKEENDGGCIEDEEGVVVAKLKQKTSFKGWFGKMLSHGQVKSSSTCP
SMQCSSADSDSLVSRNRNQWEFYEQDIEEYYQELMMSESKSIEDKDNNIDEIQPYSMNDL
NEQNILADGIQGPGDRVEELKNKIQAARKLIESNKNVAKAEVDRQAKASWAICLCNHRAE
QLQAHTEEEIKIRNDLTKEIEETKEDIQETSPAVEDSNKRLNSLFERQSELSSRLHFSSL
AKLGVEGQLEKAAKTRAELVKEIEELRKQRDVFQRRIDFCKEKDAIGLATRMSEPVSCSY
REFSANEIRLATDNFATYRRLASGRDGSSVYKGRISCMSVAVKMLDSHVGMTQETFQAKV
NLLAYIRHPNIIAFIGFCSELKCFVFEYMHNGCLRDILFSRIKARTLKWHQRIQIATQVT
LALRFLHLAEPRPIVSGYLNPSAIFLDRNVVAKLQSFNLTPCSNESDIQAEVVSFGDLLL
QLLTGRNWTGVHEAKTIDKHAIFEALDKNAGDWPLDLVEEVVELATKCRSINCETSVGAF
MSSVTEELNRLKKKADEVITRKEDHILSEDHTSSGHEWSHAPTSFLCPILQVVMENPHIA
ADGYSYELEAIEEWLRMGHDTSPVTNQKLKHKQVIPNKNLRFLIQDWRKLTSLLENANSS
NDDDSGHLNMQSTGVPMCLFNNKMVWEAFGSLDM
>Sgl33709 DUB/USP 187.9 0.4
MVRWNQMKLKREIRVSSLLNKFKTGYKMLSNIQWVSAYGSHLSAATILGMVGLLLAVRDG
RIVNITSFSTTNCSSEKLYFVPGLKNLGNNCFLNVVLQSLASCLRFRSFLEDVLELQASL
PVVQVDASPLLISLSDLLEELSTLQEKSRPLNPQKVMAAMQQYIPQFQLSNQQDAAEAFL
HLLSCLRDELSDSYMPNYGSLTDVAAPTSRILAFERIDNSKEPERWQKQYLGPFDGILGS
FLTCQTCSSEIMMDFGFFHTLPLSPIPYSGASIMHNFTLEDCMKRFLAPEHIENYSCSRC
WHIAATKFLSTFGGQQEDIRKLSCCSEQDLCNCRKISSLQTLPWTNHFSRAFKQLSIAHC
PQILCFHLQRNSMNAFGEFVKIQGHIFFPLILDLSPFAKYEVGIENLKTKNSKSVAEKPC
VASTTYQRSVDRDSNPITIETFQYFPDPCSSLSEIYSNSEVMHTLEITDGPAVPKSILYR
LVSVVEHFGRAGSGHYTVYRGVTTETEDAGETKTHLQWFRISDSEVHNASEEDVLGAEAT
LLFYERI
>Sgl33712 E3_adaptor/Cullin_RING/DCX/DWD 107.8 22.2
MSGGVEELPKKETSVLRGHEGAVLGARFNSDGNYCLSCGKDRTIRLWNPHRGIHIKTYKS
HGREVRDIDVTLDNSKLVSCGGDRQVFYWDVSTARVIRKFRGHDSEVNAVKFNHSSSVAV
SAGYDRSVRAWDCRSHSTEPIQIIDSFQDSVMSLCLTNTEIIAASVDGTVRTFDIRIARE
LSDNLGHPVNCISLSNDANCVLASCLDSTLRLLDRSSGELLQQYKGHVCKSYKSDCCLTN
TDAHVTAGSEDGFIYFWDLVNATVASSFRAHASVVTSVSYHPKDNCMISASVDGTIRVWK
T
>Sgl33729 E3_activity/RING/U-box 106.2 0.2
MGKQDLYISIPSFFRCPISLDIMKSPVSLSTGVTYDRTSIQRWLENGNNTCPATMQVLDS
KDFVPNHTLQRLIQIWYNNHNHLSQSSKSKPPQFHSLSANQIADLIKQLLGGQIIKKRVL
FESFVKILCFATESAENRRFLASNQPFLDHLVFTVSAEVGPSSDPDLLEAVLKTLHLVIA
SRDVNLSHVRQKMGNSCDFLQTLVRILRTGRPGSKVAAIGIIEELRRHSESKKAVFDHQE
LVPELLELVKCGKLEKDGEIQAVLSCLISLSCTRRNKLKLVRAEGVKLVGDILSSYQTPN
NNSDNSSNNSNSKNVIIMIELLLTLLEMLAGCTEGRSAISEDPNCVPMIINKLMKVSKAA
NEHGIALLWSMCYLFRDQKARDSVVNSNSGLTKILLLMQSDCSPAVKQMCCDLLRIFKVN
SKSCLSSYETKTTHIMPC
>Sgl33730 E3_adaptor/Cullin_RING/DCX/DWD 95.3 7.8
MVRCVSVEEDMFFDSVDHLLSTEDDDSSYVEMGVLSYEFWKGEPRSIKERRENFLQEMGF
DAPCSSSLELFNAVDDDVGLEVGMERMVVGSNEAVSSSSSCSTTDDCEEVEFCGRECNGN
SAEKEDVSQSECKVSNSKKCKCINKKIRHWWKEMMNKQRERVGGCKCKLYNEECKKCERS
RTKVQVNKKKIKEISALFEAQEIRAHEGIIWTMKFSPNGQYLATGGEDGVVRVWRVKPVD
SSLEKLKTSFRREKKVMIPVVVPDKMFRIEQVPVQELHGHVADVLDLAWSDSNFLLSSSM
DKTVRLWQLGSDVCLNTFHHTDFVTCVQFNPTDNRYFISGSIDGKVRKWGVSEQRVLDWA
EIRDAVTAVCYQPNGQAFVVGSLNGSCRFYETKGELFEQSAHVQLHSSKRSATNRIAGIQ
FSPEDPQKVMVMSEDSKLRILDKMDVVSKFRGHTKSGSQTSASFTSNGRHIISIGHDSNV
YVWNHEETVQLLPKQTKSTRSCEYFYSDGVTVAVPWCGTETAAPKVDSSGSTEHDPACIG
RDPPNFSLSNMLASKSSATWPEDMFPIFNQPEQQCQTRNNVIARCNPVWGLVIVTANRDG
MIRTFHNYGLPIKA
>Sgl33742 E3_adaptor/Cullin_RING/DCX/DWD 74.1 5.8
MKGGTVQINWHDTKPVLTLDFHPISGLLATGGADFDIKIWKVDSVEEQKKTPSASYQTSL
CYHSSAVNVLRFSPSGEFLASGADGGELILWKSHITDAGQVWKVFKTLSFHRKDVLDLQW
SRNGTYIISGSVDNSCIIWDAEKGSVHQILDAHLHYVQGVAWDPLSKYVASISSDRTCRI
YVNKPQKAKGVEKMNYACQNVIVKAEQQSADDAKSVKNNLFHDETLPSFFRRLAWSPDGS
FLIVPAGLYKCSPESESINTAYIFSRKDFSRQLPSASKPVVAVHFCPLTFNLRGSTSAGF
FKLPYRLIFAVATLNSLYIYDTESVAPLAILAGLHYAAITDIAWSPDGNFLAVSSQDGFC
TLVEFQSDELGSPIPFPDGKTEICPVGVTLNQQKPKEVLVKTSVKDRPVVIENNKTDNKQ
AVPVATNASSKPAICPVGVIPNQQKLEEVLLKTSVEDSPVIKNNQTVHKQAVPVAKSTPV
SSKPAKRRITPMAIDP
>Sgl33764 E3_adaptor/Cullin_RING/DCX/DWD 33.1 0.6
MAQDLPGFYFDPEKNRYFPIKGPIPGSSRKQTTPLQNSDSLITKVSKNPKKDVSISKLVH
LKELCGNFVGSSYGKVSFQEECKKQLVSNPKVWKYQNTHQGADCSLGLLHITVETPQGQC
ATDALIAGDISGSVNLFDVGGIGQYFSHGMMSTAVSVWPERDEPNSHQSLKNIWLFDEAA
LMMPSSVSSICAFRKVGTDNDSFAPQQALITTLGSEYASGGLYIVNLADPVELDSLYFSD
AAMRRFSQHISLNCTVWEANIGPCGRQAVVGTSLGAKMVDLESGVSSMICSSKSDVLSVQ
LIQSGNVALCGLRNGTIVTVDARQRQRQLARHRIPCSSNKSSTLAQKKTTPFFVLRGDIQ
PSCTVYMPSSICCLESLQLYDQYFLASSMDGSINLYDHRLTNRGPVQSYEGQVNSHSRIK
LAADASESFIMSGGEDCKVRVWNINSGKMLFEEKFMNSISMSVLWQGNTERICKGRSSEE
GWHAQTPGWNAWLGSGEGLFRMQFCS
>Sgl33766 E3_activity/RING/U-box 109.4 0.5
MMREIEIMSIPELFRCPISLDLLSDPVTLCTGQTYDRSSIEKWISAGNFTCPVTMQKLHD
LSLVPNHTLRHLIDQWLLKSNHHHHHYWKMGCSSSSSTSDDIMFLKNVLESKDSSLEKRM
QVLEKVRILSQDLPWKNEGLIQMGFLPLILRLVFVKNNIITKEKSMGLVEKSLDCALKLM
PFSCLSDLNMLIEESKFESFKLLLQQGSNVVKIGLCNIIKMVCLQSSLLATKLGNDTKIL
QCLISYVNNDCNDNNHDLEVSEAGIKAILSLITTPWYRENLVKEGLVGSLMTYIVEIVER
KDKEVGSKATKALELVLEMEKGREEFMVNEVLAKDVIRALIKMVFIVSGDDEGSESAVNC
VMILCEESLEMSEEAICGGILTQLLLLLQSQCSGRAKTRARMLLKLLRSMWAKDQKHVL
>Sgl33786 E3_activity/RING/RING 13.7 5.2
MAGNMEDATPLITMSPPSPMITTSEIDLEAGPSEQIQCRICLESDGRDFIAPCKCKGTSK
YVHRECLDQWRAMKEGFAFANCTTCKAPYYLRVHALADRKWRTLKFRFFVTRDILFIFLA
VQLVITSLAYLVYLVDGYQEFWLQHYWGFAKHISFYYICGCEELWVAPDGGLFAAAVARS
GGLAPAAVVGSGSLSYSGGGGGVMVGKLRAVTG
>Sgl33801 E3_adaptor/Cullin_RING/DCX/DWD 21.9 2.7
MSLGLSHSLSRYKLKFSPEKGFNFGEVTNSRTIEDKEMEIDSSKSTKELAAKGQKHLEET
VDAAFQILSAMNDDELCNTTLWSTFASPPDAARVRANLPTLRSQRHTAGSTKSEWGGKTD
HNEVKSGEWNELWRVLWKIMRKVKVVLKLQRWWMQIGVALRAKLQHLGRLLSLEMVKILA
EGIGEVQLCCIGIGSFPTSCMLGTGTMQQYGYCTFRCLLRHSCWMRILDLIVLANGFLGL
NLMGQSCWNKVLKRFDQSHFTQVELRSLKSKYTSVKNQNGKVTISDLPSILAKLKAFIQS
FKEDEIRGVLTESASDMNQEIEFEDFLKDGKIRVFKWPSMDVLVDENEAYIEVKDLHFSI
DGEHLVSVGNGGPCKIWDVASSKVVASLQKENDENFRFCRFSQSSERDQVLYTLTTRGKG
VSIISWNTKSWNRIAAKHITRDPVSAFNFTLICSCSGTVEGGILIINSSKMQVQMTVKTA
HMGLLWRWGANEQCSKALFNWFVEVAG
>Sgl33836 DUB/USP 331.2 11.4
MGAAGSKLEKALGEQFPEGERYFGLENFGNTCYCNSVLQALYFCVPFREQLLEYYSNSKS
TVDAEENLLTCLADLFTQISSQKKKTGVIAPKRFVQRLKKQNELFRSYMHQDAHEFLNFL
LNELVDILEKETQATKGDQETLSSEKAANGPTNVQANHFQKEPLVTWVHKNFQGILTNET
RCLRCETVTAREETFFDLSLDIEQNSSITSCLKNFSSTETLNAEDKFFCDKCCSLQEAQK
RMKIKRPPHVLVIHLKRFKYMEHLGRYKKLAYRVVFPLELKLSDTVEDADREYSLFAVVV
HVGSGPNHGHYVSLVKSHNHWLFFDDENVEMIDESAVQTFFGSAQDYSSNTDHGYILFYE
SLGHSSSS
>Sgl33855 E3_adaptor/Cullin_RING/DCX/DWD 43.6 0.3
MEKLEFRYVNCCKRHKVLPNPAILSSLSKVEHQKSLQRLSSLVVVLDQLKDDDLLPIIDL
INAMCSSDVDVVDVLNESPCILHEDQVLSLMCAANQKLRTVSLQDLPFTKRFLRYLFQYG
LCCEELKLSSSSLQKLDMVGCFMQLRKLNLDFCTALTTLNKDCFSHMPNLMQLSLCETRV
TNLWTTSVALSKLPSLIELRFQNCLCCEDTGPCPSTNKLGFHVRNTDHPTGPTSTCSDHL
QNLSLLDLSTDHYCSKKAFHDEPDVYDGCDTDLSEALEVVSTRKKYISHHPSPLCFEKHY
REFLIATLPRLEVLDNIPIRKKDKKLAQVLYSTYFEYLPYRRHTENNVSRILHNREIASG
GTPFRTPLKSKQASSHRKNQHSFSRSLCAAKLGASPWPLLQSLSNTSCVTNEVSRRFRPR
QFEYHPSDASLMAFGTLDGEVVVINHENGNFFAYVPPLGARNSILGLCWLKKYPFKVLAG
SDNGMLRLYDVSNTSAKGGYSCYGGDFTTADKFDQLTSVHINSTDELLLVSGYTRNVAMY
DMVAGKRLQLFSNLHEEPINVAKFSHLSPFMFATSSFDHDVKMWDIRQRTVRPCYTATSS
RGNVMVCFSPDDRYLLVSAVDNEVKQLLAVDGRLHTDFGIASSGSSHNYTRSYYMNGSDY
IISGSSDEHVVRICCSQTGRRLRDVYFEGKGSDKAMFVQSLRSDPFRPFNMSILGSYAQS
NSKCEIIKVNLLSSSEDTEENSYLQQSSCLSFSLGG
>Sgl33867 E3_adaptor/Cullin_RING/DCX/DWD 169.7 16.3
MVAVYNKQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXREVKAGKEREEKAGKVKE
EKAGKERDEKIVKEREEKAGRQWEEKAGKEKEEKAKLQDGAFDKESIVDREEKPVLKKED
DGVCPDPEPMDMSPSAPSVECEIFASDVTILEGHTSEVCACAWSPSGSLLASGSGDSTAR
IWAMSERGSRSHIGSTNFVVLKHVKGYTKEKSKDVTTLDWNGEGTLLATGSYDGHARIWN
TNGDLKSTLTKHKGPIFSLKWNKKGDYLLTGSCDKTAIVWDVKAEEPKQEFEFHSGPTLD
VDWRNNVSFASSSTDNMIYVCKIGENSPVKTFAGHQGEVNCVKWDPTGTLLASCSDDSTA
KVWSMKQDGFVHDLKDHSKEIYTIRWSPTGSGTNNPNQQLVLASASFDSTVKLWDVELGK
LLHSLNGHREAVYSVAFSPNGEYLASGSLDRSLHVWSLKEKKIVKTYSECRVCMTVRVLE
DPRLLTIWLSLDLECTWNSSVV
>Sgl33886 E3_adaptor/Cullin_RING/SCF/F-box 19.7 0.1
MGQSTSTPAHSSELVRNHSRSFSFASRFTSSSSRKKTNNSMIPPSSPPHPQSPPSKPEPT
SGSYFSLLPDPTSNIPDECLAHIFQSLPSGDRKRCSLVCKRWLIVEGQSRCRLSLNANFE
IASHLPSIFSRFDSVTKLALRCDRRSVSISDDNLVLISLRCRNLTRLKLRGCRELSDLGI
AAFAQNCKSLKKLSCGSCVFGAKGLNAVFEHCVLLEEISIKRLRGINNDGDSEPVGEPIG
PGLAAKSMKSICLKELYNGQLFGPLIVGSKNLKTLKLIRCLGEWDRVLEMMATSNSNSTN
SEGNYDGLVEIHLERIQVTDFGLSAISSCSKLEILHLVKTPECTNLGIVSVAERCKLLRK
VHIDGWRTNKIGDEGLTALGKNCANLQELVLIGINPTTTSLDVIASNCRNLERLALCSSE
TIGDVEMSCIASKCLALKKFCIKSCPISDDGLEALAGGCPNLVKIKVKKCRDVTREVVEW
LRGKRESLIVNLDADEIEAVDASASEAGGAQEDATDFPVVDTEVTSVQAPGRSNGRGSLF
RTKFSFLFGRNIAACALRRWSTGSSNTNGNE
>Sgl33907 UBD/UBC-like/UBD_UBC 91.8 0.0
MSGGIARGRLAEERKQWRKNHPHGFVAKPDTQPDGSMNLLQWQCIIPGKSGTDWEGGYYP
LTMHFSEEYPSKPPKCKFPAGFFHPNVYPSGTVCLSILNEDCDWRPAITVKQILVGIQDL
LDSPNAADPAQTEGYHLFIQDTVEYKRRVRLQAKQYPATI
>Sgl33909 ULD/UDP/UFD/UBX 29.9 0.0
MGDMKDKFKGFMKKVNNQLAPSSSGKFQGQGRVLGSSSSSSSSGSQYVNPNRNFNPSSAN
SKPFSNNNPNSNPPITRPTSLEGQKDSISNTNVISNSSSNSNPDLNRNQPSKDGFDPFGS
LITTGKRNKNGYSLNVFECPICNSGFGSEEEVSLHVESCIAHTGSNDVGSGSGGGDADVV
DSNLGYVEEVSADNEDKSTNKLETCVGVYLSGNPGEGSIDVVLRLLRNIVKEPENGKFRR
IRMGNPKIKEAIGEVAGGIELLEVVGFELKQEEAEMWAVMDSPSGERIALLKDSVQLLEQ
VKGGISSACLVNVDEKVETEKKLKESEPKIIDRQIKVFFSVSENAAARIVLPDSFYNLSL
DEVRREAEMRKKKLAESQLLIPKSYKEKQAQAARRKYIRCIIRVQFPDGVVLQGVFSPRE
PTTALYEFVSSALKQQGLEFELVHPLPVKRRVIPCFPAAGEKASRLEEEDLVPSALVKFK
PFETDSLVFTGLTNELLEISEPLVSSTS
>Sgl33922 E3_adaptor/Cullin_RING/SCF/F-box 19.9 0.0
MMMMKLSIMGEYEKEEESEIEKLPTDLLSHIFFLLTSFTDLAQASCVCKKWREGVKQSMG
RRESLSFSGCKMDDASTSRLVHLAFSLKELDISRSRWGCQITDIGLFEISMAKCVGKMTS
ISLWGMTGITDKGVVQLVSRATSLQHLNIGGTFITDESLVAIGNNCLHLKTIVLWSCRHV
TEIGLLYLVSKCRNLKSINVWGTRVPVNCFIGLLTISPALQIKPTGLLPNAEAIPV
>Sgl34025 E3_activity/RING/RING 17 0.4
MNYWKAGAMYRGSTPTPVAQIPFRFNYISKKLQAPNHMDNLISLPEKKIIEVLLECVERK
NLPEAYKGNLRVSCKCFASGSQHFVNKWIQVVPKPEISTYEPILIHVSLSITPPTPAPQV
FHMLPFVNEVKDQTLVIDTDGNNVLNLQMREFSTPGLSKEVIHITRNENGGRLFELSGHK
MAWCDVLFLGRKLDYEPKNDEKKRSEQDFMSAVEFSVEYPYGRAIGLLDYNHGILKQVEV
AEVGVVGGGLPCGHLFCNSVELGSPEMMIHPKTTKNKTDFGVVGIDASIVDVQQGISQNE
WCSEDGCSNEYGNAIIYGGRGGVYSCSGDGGGGGGGGGGGGGGGLPCGHLFCNSVELGSS
KIKPLMKTTPTS
>Sgl34054 E3_activity/RING/RING 31.4 8.7
MAFMQIPCCHNFFPIGKRVDVRIKYRVFERCTFVDDDENEFVTQFYPYNQGSETILGINP
YCPDCKVELTTLFELMSYSVVECSTVVGFIQAKVERLLSQSQLELDHDNNDDLGDYSISL
DFYRRFERTFDEVTVRAWLERHSSVDAIDEEPGDCTPASEEAIQSLERITLTTSRKEDGS
AATCAICLGLMMRKNNNEFGRRMPCKHEFHEDCILKWLHTSHYCPLCRFELPTSSSSSKE
VDSHELVIRDSDDVFTIDCSEQ
>Sgl34055 E3_activity/RING/RING 32.9 7.3
MDSIQVPCSHDYSTSGRIVDITITHQNFEEHVYHIEDGSDVRRLNPLNTQTTPMSINPKC
PQCRDSLIASFDSIISPERTCTAVLDIVQETIDNLVSNNSDHDHALATLIMICFIKRRHY
HDYDENSAMEWAERASFEEAFKAGFTPASPESIRALERITEISSDESTTCAICLEQLLKN
KEEVGRRLPCRHEFHESCIFKWLSISHYCPLCRFQLPTFSSITPL
>Sgl34072 E3_adaptor/Cullin_RING/SCF/F-box 19.4 0.0
MGKPRKTPIKTLNTNNNVVVSLPQEVQPNILTSLPVKSLLQFRSVSKTWQSIIDNPTFAY
THYSAAQTRPGSARILLSFSNSDRSRHYLYSTGVFGGRAVHHLTLPGDGTAQGCYFLPPV
KGLVCFVSSNNIYVSNPSTRKVRILPHCPTIYKKTNLNNSYLYKPYSCYSFGFDSFSRVF
KLLHVFGTICRNDNKLYNVESRVLTLKTPDHFSSDSISWKKIESSFPYPYPFKSQGVFVD
GCICWVGMESQGEGNIVAFDLRHEKFRLIPSPPNGVSSKSKLENIEGDLGVMSFKDYDDF
SLELWVYQNNSSTWVKKDVGLQFALKKKKGNNTSFPTFVGNSYTGGMLLSQDVLLHNFVL
RSLNGSSTCRERGVRITGLPGWVDFLDYKKVNFCTSQYVESIVPLDFVVRLGDFVVDLAA
VKHPKQPLVVKLLPHKEVEVKNVAKEWKIEELVFGDLKEFQKKNQPSSTTVEDAKRSVDS
KSNGKWVKKVKSTSTKNRLKRN
>Sgl34088 E3_activity/RING/RING 57 30.6
MAVIQIPCSHDYYPSGKRIDVLFKYRVFDRCTFVAEDDTQIVTPFYPYDNGAETILSINP
YCPDCKAELYALYASMTHSEEEWSDMLKLVRDEIEAVVPRLLKVPDFYDDDYLGSLNIGV
DFYRCVILDYDEESVREWIERVSFTSEEGPNCIPASKEAIDALERITTATTSTTTSISTC
AICLEELFVTKDEVGRRLPCKHEFHEDCILQWLHTSHYCPLCRFELPTSSSSLSSSIDIE
SYIPIGTRVDVQFEYRIFQRCIFEVDNGDDIVTPLYPYNGTQTTTLPINPYCRHCKAALT
TLFLSINYSEAACSSMLEFIKRDLNELFSRDLHYCDLRYNLQAHFTIQYRAPYSEAALRE
WEEVIANLEVVELEQAATSYVSATYETTDSCLERMITATTTSITQGETATCAICLDELFV
RKDQIGRRLPCKHEFHEHCVFKWLRKSQNCPLCRFELPTIPSHEKDL
>Sgl34098 E3_adaptor/Cullin_RING/DCX/DWD 77.9 12.3
MIAAISWVPKGVAKSVPEVAELPSKDEIEELLQSGALDTVDGDHDDDEEEEMDTESIKEA
DEVALASVAAEALVKDTKDIAEAFKDLDMDNYDADDGDDGIDVFSKGLGDAYYPSNEVDP
YLKDKDDNDSEEEEDITIRAEDSIIVCARNDEEISQLEVYVLEETEDGPNLYVHHDIIIS
AFPLCTAWLDCPLKGGERGNFVAVGSMEPSIEIWDLDVIDEVEPSIVLGGIIEKKKKKKG
KKKSIKYKQDSHTDSVLGLAWNKEFRNILASASADKQVKIWDIATEKCSITMEHHTDKVQ
AVAFCHHVPQILLSGSFDHSIVMKDGRKPSHSGYRWSVAADVESLAWDPHTEHSFVVSLE
NGLIQGFDIRVASSNSYSEMKPSFTLHAHDKAASSISYNPSVPNFLASGSIDKTVKLWDI
SNNQPSCVASQNPKAGAVFSVSFSEENPLWLAIGGSKGKLEVWDTSSDAGVAKKYASSHS
KKP
>Sgl34186 E3_adaptor/Cullin_RING/DCX/DWD 111.6 14.4
MFARSNSAQQQAQLYSDNNFENHQCEPCTSNVESTNSSPSENVGSLSPYAKSPWSSHMAI
SNPMFEESFSTKGSSYNCLMGSLIREEGHIYSLATTGDLLYTGSDSKNIRVWKSQREYSG
FKSNSGLVKSIVISDDKIFTGHQDGKIRVWKMSSKNPSIHKRIGTLPSFKAYMKKSIKPS
SYIDIGRRRNVWIRHLDAISSLSLSEDRNYLYSASWDKTVKVWRTSNFKCLESISAHDDA
VNAVVAGFDGLVFTGSADGTIKVWRREVQGKGTKHFFSQSLLKQECAVTALVIDPTSTLV
YCGSSNGQVNFWARNNFAFPAGTLNGHKLAVLCLATAGSIIFSGSADMNICVWRRIVNEE
MNTEDHVCLSILTGHNGPVKCLAVVASGETTSPDSRWLLYSGSLDKSIKIWRISEEVPNS
IISYTRSNTQQQGLSFAFR
>Sgl34219 E3_adaptor/Cullin_RING/DCX/DWD 47 9.8
MAKTKQTDKTKKEKQKIAKERQKLAKEKRISDKKEEKKNQKLLKSKKKKTSRDSLTKFNF
DDKDDEKSQIPDYHEASEAESSGRRSSGSDVVSNDTRVNDANTSGNDDSDAYHTAEESDS
SEDEVPPRNTIGDVPLEFYNDEEHIGYDIIGKKIKKKDRIDSMAKLLAKDDAKSWKKVYD
AFNDEEVELTKQEIKMIRRISKGKTPHADVDPYAPYVDWFDWDGKGHPLSNAPEPKRRFI
PSKSEGKMINKYVRLIRKGVIKFDKPKEEPRFYRLWDDDSSSSVKTRGLSYIPPPKAKLP
GHEEAYNPSLEYIPTQEEINSYQLMYEEDRPSFIPKRFTSLRGVPAYESFLKECFNRLLD
LYLCPRKRKKRLNVELEEFKPKPPNPKEFKPYPTTCYIEYKGHTDAVVSISTESTGQWIA
SGSIDGTVRIWEVATGRCVRVWEVGSAVRHVAWNPLPHQPVLAVSVDRDVLILDTGLGSE
EDQWKIRDLLKFEKHASPDESGDAGIVSWHFDDKLGGLRLKHFKAVSSIEWHRRGNYLST
LIPSDILQFIFVLLFSIYSLLISFIIHLSYEVQTTEWLGSVVSDYIYMSDYINVLYLMIS
ATLLASCVFLTLFLRESRAIVIHQLSKKESQIIPFKLHGLPVSTAFHPSRSVFFVATKKN
VRVYDLLKEKLIKKLDTGLREVSSIAVHPGGDNVIVGSKEGKLCWFDMDLGTDPYKSLQH
HNKDITNVAFHHSYPLFASCSEDGTAYVYHGMVYSDLNQNPLIVALRILHMHSGAKESGI
LDCKFHPRQPWLFTAGADSVIKLFCH
>Sgl34224 E3_activity/RING/RING 30.6 9.8
MGIMAETPNNGDFPCVILYCDKDNLNLTSCTVTCLPSVETFPLPSRPPPPPPSPSPPPSQ
SHLAPYLIAIVCILGISFLLLTTCTIILRYRFTRRREEDDHTISDNSGVNDDQPFVDHPI
WHITTVGLQQSVIDSITAFKYKKIDGFFVDDSDSFCSVCLTEFEDGDDLRLLPKCCHAFH
VSCIDTWLRSHKNCPLCRAPIVNEGLEGNSVVGNINSNDSGLRGESQRMNLDESDGGEGS
SHQFREIGDDLGRLPVLEGIKIAEILRKNRELRIFSDLGANHRFRGVEDGGLESVRRSVS
FNAVAALAKSGTMMSISNGGCSSDWSFNEGCSNGENSKGVLKQKKTDIEKGGGNKRGSSM
SGLLIKSSSSGRSLQKGPVSMKRSLSTSSRFFSFRRSKSQASILPL
>Sgl34227 E3_activity/RING/RING 38 5.8
MKTVHCSSTLFQISLLSLILISLLLHQAEAQKPPDSTISNDIDDELEGSRVSPSMAIIVI
MLVLGFLTTGCISIYIQQCSDNSSIGEALPVNGQPIRSVQRGLDQSVLDTYPTILYSDVK
ELKIGKGTLECAVCLNEFEDDETLRLLPVCDHVFHPQCIDAWLSGHTTCPVCRANLVPMD
NSPGSHSDEDSLNRLHPSDDNNNEVEIAVTTYPPKGKMPRSHSTGHTLVPLMRTAEDHER
FTLRLPDEVRKQLLAARPRLKRTTSMVALPRVSSSRRGYRSGGGGGEGSGSSRYGRFFVR
SFRWSTKNNNGYDGDTYTGSKRFFGTVVKPSEGLPRLPV
>Sgl34239 DUB/USP 240.7 1.1
MLQIPLLLSVALWIFTVILRWSLKNEESKKTTASPEASMADFDAFRGDFSNSAPPMVVNF
DEFQGELSDSSPTMAMKPRYECAVCLSLTSTRCSRCKAVRYCSSKCQIIHWRQGHKHECH
PQDHSASEKDDFDENADSVEQCKTNDISSAEYFSRMDDKNISQHRHDDVFDLPVPRLSTV
TVASFDTGRSSCGENETLSSHIDATKMGHREDKINSMEMNASTGLTPNGAVNSVRKLKKK
SRQDDRRKFRPSNSEHSPGSQQDKSDRTFGNVPSSKAEEVLFVDNDEQKHSSYSVPPRRS
VSNELSRNGLASSFQKVVHHFKASNQKKPSPHDTLLGISANRNCKTIFPYDAFLKLYSSN
EVELRPFGLINCGNSCYANAVLQCLAYTRPLTMFFLQGRHSKECWKEEWCFICEFEELML
NGSKGYTPLSPIRILSNISHLGHGREEDAHEFLRYAVDTMQSVCAELAGVVGPEREESTL
VGMTFGGFLHSKIRCLKCNSKSEKYERMMDLTVEIDGDVRTLEQALRRFTASEMLEGDNK
YHCNRCKSYKKAKKKLTIFQAPNILTIVLKRFQAGSFAKLKKPVQFPEILNMTPYMSDSS
DKDKHPQYNLYAVVVHLDVSSAEFSGHYVCYVKNNRQEWFKVDDTVVISVDLMRVLSEEA
YMLLYARDSPRPPISGRKSYDGQSDVVNFEVPSKGRHSSSDVSVDPWVRQHQSSKSGYAK
DPSFVEEWVTSSVKSIPRADSSSEVSSLFSNSEEGTCSTPSTKDSASVDDFSDYIFGRGS
TARH
>Sgl34258 E3_activity/RING/RING 33 7.0
MAFIQIPCCHNFFPIGKRVDVRIKYRVFERCTFVDDDENEFVTQFYPYNQGSETILAINP
YCPDCKFELSTLFELMSYSAVECSTVLGFIQAKVERRLLSQSQLELDHDNNDDLGDYSIS
LDFYRCFERTFDEVTVRAWLERHSSVDAIDEEPGDCTPASEEAIQSLERITLTTSRKEDG
SAATCAICLGLMMRKNNNNNNNDEVGRRMPCKHEFHEDCILKWLHTSHYCPLCRFELPTS
SSSSSKEVDSHELVIRDSDDVFTIDCSEQ
>Sgl34259 E3_activity/RING/RING 32.7 6.9
MDSIQVPCSHDYSTSGRIVDITITHQNFEEHVYHIEDGSDVRRLNPLNTQTTPMSINPKC
PQCRDSLIASFDSIISPQRTCTAVLDIVQETIDNLVSNNSDHDGALATLIMICFIKRRHY
HDYDEDSAMEWAERASFEEPFKAGFTPASPESIRALERITEISSSSDEEATTCAICLEQL
LKNKEEVGRRLPCRHEFHEGCIFKWLSISHYCPLCRFQLPTFSSIIPL
>Sgl34290 E3_adaptor/Cullin_RING/DCX/DWD 19.6 0.6
MSGYSGVVVSNHSLQSHFTQVELRSLKSKYTSVKNQNGKVTISDLPSILAKLKAFSQSFK
EDEIRGVLTESASDMNQEIEFEDFLKDGKIRVFKWPSMDVLVDENEAYIEVKDLHFSIDG
EHLVSVGNGGPCKIWDVASSKVVASLQKENDENFHFCRFSQSSERDQVLYTLTTRGKGVS
IISWNTKSWNRIAAKHITRDPVSAFNVSIDGKLLAIGTVEGGILIINSSKMQVQMTVKTA
HMGLVSALTFSHDSSVFIYEMKLPSLFDCLLCSYFSGVYPVMPEPPAIGGYEGVGEVYAV
GSGVKGLSPGD
>Sgl34296 E3_adaptor/Cullin_RING/SCF/F-box 19.4 0.0
MGKPRKTPIKTLNTNNNVVVSLPQEVQPNILTSLPVKSLLQFRSVSKTWQSIIDNPTFAY
THYSAAQTRPGSARILLSFSNSDRSRHYLYSTGVFGGRAVHHLTLPGDGTAQGCYFLPPV
KGLVCFVSSNNIYVSNPSTKKVRILPHCPTIYKKTNLNNSYLYKPYSCYSFGFDSFSRVF
KLLHVFGTICRNDNKLYNVESRVLTLKTPDHFSSESISWKKIESSFPYPYPFKSQGVFVD
GFICWVGMESQGEGNIVAFDLRHEKFRLIPSPPNGVSSKSKLENIEGDLGVMSFKDYDDF
SLELWVYKNNSSTWVKKDVGLQFALKKKKGNNTSFPTFLGNSFTGGMLLSQDVLLHNFVL
RALNGSSTCRERGVRITGLPGWLDFLDYKKVNFCTSQYVESIVPLDFVVRLGDFVVDLAA
VKHPKQPLVVKLLPHKEVEVKNVAKEWKIEELVFGDLKEFQKKNQPSSTMVEDAKRSVDS
KSNGKWVKKVKSTSTKNRLKRN
>Sgl34312 E3_activity/RING/RING 59.8 29.9
MAFTQIPCSHDYYPSGKQIDVLFKYRVFDRCTFVAGDGDTRIVTPFYPYNNGAETILSIN
PYCPDCKTELYALYASMTHSEEEWSDMLKLARDEIEAVVPRLLEVPDFADDDYLGSLHIS
VDFYRSVILDYDEESVREWIERVSFTSEEGPNCIPTSKEAIDALERITTATTSTTTSTCA
ICLEELFVTKDEVGRRLPCKHEFHEDCILQWLHTSHYCPLCRFELPTSSSSLSSSIDIES
YIPIGTRVDVQIEYRIFQRCIFEVDNGDDIVTPLYPYNGTQTTTLPINPYCRHCKAALTT
LFLSINYSEAACSSMLESIKRDLNELFSRDLHYCDLRYNLQAHFTIQYRAPYSEAALREW
EEVIAHLEMVELEQAATSYVSACYETTDPCLERMITATTTSITQGETTTCAICLDELFVK
KEQIVRRLPCKHEFHENCVFKWIRKSQNCPLCRFELPTFPSHEKDL
>Sgl34327 E3_adaptor/Cullin_RING/DCX/DWD 77.9 12.3
MIAAISWVPKGVAKSVPEVAELPSKDEIEELLQSGALDTVDGDHDDDEEEEMDTESIKEA
DEVALASVAAEALVKDTKDIAEAFKDLDMDNYDADDGDDGIDVFSKGLGDAYYPSNEVDP
YLKDKDDNDSEEEEDITIRAEDSIIVCARNDEEISQLEVYVLEETEDGPNLYVHHDIIIS
AFPLCTAWLDCPLKGGERGNFVAVGSMEPSIEIWDLDVIDEVEPSIVLGGIIEKKKKKKG
KKKSIKYKQDSHTDSVLGLAWNKEFRNILASASADKQVKIWDIATEKCSITMEHHTDKVQ
AVAFCHHVPQILLSGSFDHSIVMKDGRKPSHSGYRWSVAADVESLAWDPHTEHSFVVSLE
NGLIQGFDIRVASSNSYSEMKPSFTLHAHDKAASSISYNPSVPNFLASGSIDKTVKLWDI
SNNQPSCVASQNPKAGAVFSVSFSEENPLWLAIGGSKGKLEVWDTSSDAGVAKKYASSHS
KKP
>Sgl34451 E3_activity/RING/RING 27.1 12.9
MWSFPNTIPNLRLRKVSTEPNLYCADSSDEDTGSSSSREEGLECPICWESFNIVENVPCV
LWCGHTLCQNCVLGLDWANLELPGHKLKLPFCVSCPWCSLVSFRCVYRGTLRFPRKNYFI
LWMVESLNGERAKSSSTVCDDSQRAFPSRISSHIGSVNNCSPRRAQPTQGRHWLGSNRDS
RVAGDVNVERPQFSLHKSLDYFIHVLSKFPLVILFLVTIFFVMPGCVAILVLYVLISILF
AVPSCLVMYFAFPTLERLMREIIS
>Sgl34475 UBD/UBC-like/UBD_UBC 137.7 0.0
MASSSSSSSSSAQLRLMSDLKSIINEPPEGCSASPMSDDNLFVWSATIFGPDESPWEGGV
FCVRLTFSHNYPEKPPRVRFTSHIFHPNVYHDGTLCMDIIQDAWSPCHNVATILTSIQSL
LTDPNPSSPANPEAAQLFQHDVKAYNKRVRRCARDSIECS
>Sgl34515 E3_adaptor/Cullin_RING/SCF/F-box 19.4 0.1
MSFKGIVRELKEMKGGIGSLSRRGGEGGRHWRGRTRSHIAPDQPAPCLDEAEQGRWANLP
SELLLDIIRRVEVSETAWPARSVVVFCAAVCRSWREVTKEIVQTPEQCGRLTFPISLKQP
GPRDAPIQCFIKRDRATSTFRLFFGLTPSEDETDKLLLAARKIRRATSTDFVISLVADDF
SRASNAYVGKLRSNFLGTKFTVYDSQAPQDVTVKTNSRSSRRFHSKQVSPRVPAYNYSIA
TISYELSVLRTRGPRRLHCVIHSIPLASIQEGGSAPTPHSFPQSFDDQCPPSPSVQGKEQ
AINFSSTSLSEPPPTLTEDRLILKNKAPRWHEQLQCWCLNFRGRVTVASVKNFQLVAAIE
PHHNIPAAEQDQVLLQFGKIGKDIFTMDYRYPLSAFQAFAICLSSFDTKPACE
>Sgl34516 E3_activity/RING/U-box 94.9 0.2
MKRVNGGLIWVQEEFCYFLRIVRLIREENKLFSIEFSGLLFCFVDTSVNRSLTFWMGTDV
SEVQETPTRALGIRVHVSMCTQLLGLVDRISSVFVAIEAARPRCSLGIQSLVQLHNAIAR
ARELVQNCCISSKLYLAITGDAAKRRFEGTKNLLDQSLSELQSMVPMELKLQISEILDDL
RDAIFIMDPCDELAGKALRAMLQQNVSPIESVGNSEIELLQFSASMLHLTSQKELLIEKR
YIKRLLNDLKEGNSTKRKTLKYLLHLLRKYDKLIVQQQTKNDSAHHAEAYNYVKSESKSS
GLSSHTDHASFLHWSEIPEEFKCPLSSELLRDPVIISSGQTYERSYIQEWFDDGQDTCPR
TGMKLPDLSMTSNTNLRDSISRWCMEHVIENPKPRKVTAVYGSLENSSNSFRSNASSMKD
IDLRIDASNLSFGSLDSSFSNISHANHSVNSIKELSVIHSPRFQFYHSVDDIRAQFLSNV
RGLPWESQCTAVQDLCTYLTYYNPSCAFISSKNFLDPLILFLQDAFNKHDIKAQKTGSQL
FFTFLRSSRKESEILSDDVYALLASFLGTEAAAEALAIMELLSTKVSFSDFAASGALTSI
FQVLKNNKKEFQEPALRILYKFSLSIDSSSCKLASDWVPILVPFLDDTSVAGICLAILEN
LCKFEDTKCSIVETQGCIASIIKLLEDCSCEDQERAVDILLTLCSQREYYCHVVLRECCI
PALVKVSNSGSDKGKGIALELLRQLKEINFEEGEQECPPRSNVNVSEGHHHHMGKNVNQK
ASKPSGFIRRLFKRK
>Sgl34592 E3_activity/RING/U-box 42.3 0.1
MGKKQHSKDRMYITKTEWATEWGGAKSKELRTPFKRLPFYCCALTFTPFEIPVCTRDGSV
FETMHIIPYIRKYGKNPVTGAPLKLGDLISLTFHKNSEGEFHCPVLNKVFTEFTHIVAVK
TTGNVFCYEAIKELNIKTKNWKELLTDEPFTRDDLITIQNPNELDAKKVLDDFDHVKKGL
KIDDEELKKLESDPAYNINVSGDIKQMLAELGTEKGKQTALAGGGGSKAQQERAAALATI
LAARSRIVDDPKSNGKTENKQGYSIVDAASASVHGRSAAAAKAAPAEKTAARIAAHMAGE
RAPVNAKLVKSRYTTGAASRSFTSTSFDPVTKNEYEYVKVEKNPKKKGYVQLHTSHGDLN
IELHCDITPRTCENFITLCEQGYYNGVVFHRNIRNFMIQGGDPTGTGKGGESIWGQPFKD
EVNSKLLHSGRGVVSMANSGPHTNGSQFFIMYKSAKHLNYKHTVFGMVVGGLTTLGAMEK
VPTDDTDRPLVSAILIWW
>Sgl34596 E3_adaptor/Cullin_RING/BCR/BTB 18.5 0.0
MSHESETGKDMKEGWRNLGVSQTIFEENEEEEDDHEHEYEDDDDEDEDLQSLSSPPLSFP
FSSPSSPLQSGADAWTAATGKKPDVNIQVRGVCFNLHKDVLISKSGYFKRQLTTRVSNFT
LSPPLKITADTFNQVADFYYSNHTVITPSNVVSLSIAARLLEMDGKESLCELTETYFCDV
ITVDRTLTCNVFRSCLLLLPEAEQTVFLASRCIETMLDDNDGDGAVSCADGLKMVSPEDF
RVIADSMQRRYTTSHDLLYRVVDLYFLVYNGKMSEDQKTQITSCIDCSILSAALLMHAVQ
NPRMPLRFIVQAMLIEQLNTHRSLYSVLNSTTPTTNNPSCSDSPATLGVILERDAALRQV
AQLRAAVDTTCSRIKTLEKELTGMKKLLLESEKQKQVGSKSNHRSILLDDNQRRSSSCRF
NNNSNKVERGERGSVSTSFLRFRRNNNNNNGHNYTTSDEFCDLKMGSSASCLESDNVGNG
DRNRNDRVMKRNFGQRLIRGLRNVFGVSSSTNNSKLKDSDHHIGGRKGLVTDAGDNQGVS
SSSNTTTRTIFI
>Sgl34604 E3_adaptor/Cullin_RING/BCR/BTB 32.1 0.0
MVQFTLGFLIFICLITSSSIRLLIRLEEMCKMEDGDHVVDNLVKEKIHPPPAPPLPSFPL
TIANPKMVMTKSKAKVLSSSKHQCSVNIATRDLYDRLFDGAFRADVVVHTDTGGQISAHA
SILGMASPVIRNIIKQSKDKDRRRSFTIRGVPHDAVRVFIRFLYSSCYNPEEMEEYILHL
LLLSHVYVVPHLKRECEVRLENGLLNIENVVDVFQLALLCDAPRLSLICHRMILDNFKAV
SATDGWNVMKEAHPILEREILATVAEADARQKRLFRKREERKMYVQLYDAMEALVHIYRD
GCKTIGPHDKAPKKDKHPCGYTACKGTELLVRHYASCKLRVPGGCAHCKRIWQLLELHSR
LCIDSTTCRVPLCRNFKDRIMKQNRKEEMRWRILARKIVRSKSISGAPFFSLANST
>Sgl34607 E3_adaptor/Cullin_RING/BCR/BTB 20.4 0.0
MKFMKLGSKPDSFQSDGDNIRYVATELSTDIVVTVGDVKFYLHKFPLLSKSARLQKFVAM
ANQENQDEIVIQDIPGGPASFEICVKYCYGMTVTLNAYNVVAARCAAEYLEMYETVEKGN
LIYKIDVFLNSSIFRGWKDSIIVLQSTKSLLPWSEELKIVSHCLDAIASKASIDTSKVEW
SYTYNRKRNPSENGGEQLYNGVRKQLAVPKDWWVEDLSDLDMDLYKRVITTIKTKGRVSS
EIIGEALKTYALRKLPGFNKGMIQGGDLQKNQLLIENIVRLLPREKGSVSSSFMLRLLRA
SMSLGCGEMVRTELLRRIGLQLDEASVTDLLIRAPPDETTVYDVDLVENLVREFVMQESS
VHNNSHTEIDFQELKKPVIISDSSKGMVAKLVDCYLAEVSRDPNLPLSKFISISELVSGF
PRQSHDGIYRAIDMYLKEHPGISKSERKKICKLMDCRKLSVEACAHAVQNERLPLRVVVQ
VLFFEQARATTTSSSPGCRTPDLQRPARASLPGGSHGSSRSATTNTNTEDDWDGVPTTEE
LKALRGEIANLRIGGGEGTSGSGDGPKSDAEKAAANKVRGLLMSKRLFSKLWSSKEKDGE
NSSSDTSESPASTNNAEEIRSTPNRNRRHS
>Sgl34617 E3_adaptor/Cullin_RING/BCR/BTB 20.9 0.0
MAHSIYRAIISTLLILVCLSTPYTTTALSQNYYAKTCPNVEKIVRQAVQKKIQQTFVTIP
ATLRLFFHDCFVNGCDASVIIQSTSSNKAEKDHPDNLSLAGDGFDTVIKAKAAVDAVAGC
TNNVSCADILAIATRDVVNLSGGPFWAVELGRYDGLISKASSVNGKLPQATDNLNQLNSL
FASNGLTQSDMVALSGAHTVGFSHCDKFSKRIYGFTPKNPVDPTLDAQYATQLQTMCPKN
VDPRIAVSMDPVSPRVFDNAYYKNLINGKGLFTSDQVLYNDTRTKNIVTNWAQSSSNFKK
AFAQSMIKLGRVGVKNSKNGNIRGCDASVIIQSTSSNKAEKDHPDNLSLAGDGFDTVIKA
KAAVDAVAGCTNNVSCADILAIATRDVVNLSGGPFWAVELGRYDGLISKASSVNGKLPQA
TDNLNQLNSLFASNGLTQSDMVALSGMNKQLMSSAMKRTSEWICSQEVPSDVNINIGDAS
FSLHKFPLVSKCGYLKKLISESNDSDVCNIEINDVPGGSEAFELAAKFCYGFNFEISTEN
IAMLRCVAEYLQMTEDYAVGNLVGRTESYLDEVALKSLSSCVSILLTSENLLPMAEQVKL
VSRCVDAIAFLACKDSQFSGVNKLESGIESANSVLSLQQKPIVEFWWAEDLTMLRIDMFQ
RVLIAMTARGFKQFALGPLLMLYAQKSLRGLEVIGKGKKKLEPKQEHEKRVVLETVVSLL
PRERNVLSVSFLAMLLRSSTWLETTVACRLDLEKRMALQLGQAALDDLLIPSYCLTGDTL
FDVDSVRRIMMNYLESEVEGNHLGYGAGEEHVSPSSNDLEKVGKLMENYLAEIASDRNLT
VSKFIGLVELIPEQARVTEDGMYRAIDIFLKAHPTLSDLERKKVCSVMDCQKLSREACAH
AAQNDRLPVQTVVQVLYYEQQRLRETMNETTGGESTSSAGAIFPTKTLNFYPTNTPSMEE
LLKVRRENEDLKIELLKLKMRLKEIEKPMNNIIDTNDIASVTNSPAKSFTSSAAVGGGAT
DQKPPLPRKSFMNSVKKLGKLLLPADGVLTPTRRSKSAKGRRHSIS
>Sgl34658 E3_activity/RING/U-box 29.6 0.0
MASGFEESMKAEPSSSNGGANNNDAGDFECNICFELAQDPIVTLCGHLYCWPCLYRWLHH
HSQSQECPVCKALVEENKLVPLYGRGKSTIDPRTRPVNGDDIPNRPSGQRPETAPSPPGP
DQNYFSNLGFGFLSGFMPMATARFGSITMSAGFGGMLPWSMMSAQFNGFPHNPMYGAAHG
FPFGYQQTVHGNRMHHAHGHGFGHTHEFLHQDGVARQGQGQDSLVKLLFIIGFLVFAALA
LCDFSW
>Sgl34668 UBD/Alpha-Helix/UIM 23.2 7.8
MGWLSKIFGGSSHNHRISEGHHHGRYGDDSTWDGPTTSGGELSDYDNEDIDRAIALSLAE
EEERQQNKDKKGKKVIDHESNENHLEEDELLAKALQESLNMESPVQTPPQTPPQPPPQYD
RGHMWQPYPFFSYGYRTCSGCGAEIGHGRYLSCMGGFWHPECFRCQACNEPISDYEFSMS
RNRPYHKACYKEQHHPRCDVCQNFIPTNAAGLIEYRAHPFWMQKYCPSHEYDRTPRCCSC
ERMEPRDTKYLVLDDGRKLCLECLDSSIMDTNECQPLYIEIGEFYEGLNMKVEQQVPLLL
VERQALNEAMEGEKQGHHHMPETRGLCLSEEQTVRTILKRPKIGGGHRVMDMITEPYRLV
RRCEVTAILILYGLPRLLTGSILAHEMMHAWLRLNGYPNLRPEVEEGICQVLAHMWLESE
ILAGSSSSSGASSSSSSGSSSSSSSNSSKKGKRSQFEKKLGDFFKHQIESDASPAYGEGF
RIGNQAVSKYGLRRTLDHIRLTGTFPC
>Sgl34697 E3_adaptor/Cullin_RING/BCR/BTB 18.5 2.7
MATEKSGTSTPSKGQAWFCTTGLPSDVVIEVDDMTFHLHKFPLMSKSKKLHDLIKEQEIK
QVSKQRQKQIRETDDIESSEEDEEVPEEEQCHVSFSHFPGGTETFETAAKFCYGVKIDLT
AAKVAPLRCAAEVLEMTEEYSEDNLISKTERFFTNSVLKNIKDTIKALISCENLSPLAEN
LGIVERCIDAISSKASLYDPSLFGWPVNDVTVSTASDSRKKNATSSKLRDAWVDDLAQLS
SQLFNRVISSMREKEITPEVVESCLIHYAKRCFPGISRSNRKRTSSSTMMASEAEQRQLL
ETIISNFPQEKSSKSPAVTSFLFGLLRTANILNASDACKSALEKKIGGQLEQATLDDLLI
PSYSYLTETLYDVDCVQRILGHFLATYEETTDNVEGGDQTLGNVRSPAIMLVGKLIDGYL
SEIASDSNLKPSKFIELALSLPQKARLYDDGVYRAVDVYLKAHQWLSEDEREKISGVMDC
QKLTLEACTHAAQNERLPLRAVVQVLFFEQLQLRHAIAGTLLTADAAVSESPRPSAQDEE
AEEEQEDTAVAGRETGNNHTWREAVRENQVLRLDMDSMRTRVHELERECSTMKKVIQKID
KVGTSQTWRSSLTRKFGCKFKTQVCDSHESAVVEARKGRHHQSNQR
>Sgl34756 E3_activity/RING/RING 27.7 11.6
MTASTSNTDAQYKYKMTALPVTKLAYDGARRSASDVNSSSLLMKIKYKVYLFHKSSHINN
INDDDNPDAVVRNKVRTRRMSVRYSVPWRHLISDDDDGNPNSNSWSKMSEVITHASSYIP
FPQSTLYWTDYQDRKKITPLDNQNQMITRILQTARSMVSQPTDSEAIHNNNYNNTSYQLN
LCLKKEIYLDHDEYVTRVCQSELDYRKWNIIRRCINRLQPPLETETVRRELIACLRAGGI
NNQIHDGGIDRLTNWVMMLFSGRSIRESMWHTTKPAAEDVIKNLQSHILDSDEVCPLCLE
TMIEGDVVNQLPCSHVYHPDCIMKWLHQCNSCPMCRFPMPI
>Sgl34757 E3_adaptor/Cullin_RING/SCF/F-box 12 0.0
MDKGKNQAKSGAVSKPNKIYMDLREIIQEHALRYLPAKSLYRFKAVCKDWKLQISTPFFE
HSQSVSFSSLSGLFWQYPDGSISFIPLDPMAHGVLDPELKFLPELVDVLSSSNGLVCCRG
RSGEKAYYICNPVNQQWKKLPKHEADHGQHLSPVLVFEPSLLSFVAEYKVICAFPSTDFE
GAYEFEIYTSTKDLWEISPEICFGENGRILKSGGLHVNGVVYWKSNNYALIGYDLKKNRV
KVIPTYELGGSFTFGIMDGKVCASSMKSSMVTRCLLSNEYANTMHMISESKTWEKRTTML
SHVRISDEAILLAVGGDTIVFSEGRQFFCHDLRTKETKRLMTNVEYNLLNFYVPCVNSLV
RLE
>Sgl34783 UBD/UBC-like/UBD_UBC 90.5 0.0
MTASSATSRKTLSKIASNRLQKELAEWQLNPPTGFKHKVTDNLQRWIIEVNGAPGTLYAN
EIYQLQVDFPEHYPMEAPQVIFMQPAPIHPHIYSNGHICLDILYDSWSPAMTVSSICISI
LSMLSSSTMKERPEDNDRYVKNCRNGRSPKETRWWFHDDKV
>Sgl34828 E3_adaptor/Cullin_RING/SCF/F-box 14.7 0.1
MSCRRVSWSDFPLELLLKIVGCLQSRSDIQNFRAVCKTWSRSISSSFVTSRNILSPLLPH
SLRPSSRYDSYWLDSDSSRQSPVLVATHVFLFRSITAPTASPWLFTAEELHPRKLFVSKL
LSPIAIETFPTDFPKTIDLSYIQVSELAAFHRLRFVDDATDMFTTKNLYDFNDNRVVLFK
NPKCTKTCPSISDCTAMILHHNGALCAMRLRNGKELPLGSTRKFDDIVNFKQKIYAIDRK
GRAYMMDYGSLSLTDFIREPLNEVYFEKRKRLAVSSDCQELYLIYRWCRSKTSDVVAFNI
YKLNEKERKWDEVGGIGDDMILFVTFDGCFFVSAKDFQGWKGNCIVFYSACFASYSVSSL
TNRDRVISLSVYDFEDGDCQFLASYQSKLLWPPPAWLSSPACMSKRKLEQDEVMQPGSSC
RPSTEPLDVQNHVTMNNVRNVAGEAEESMRSITSSEIFKSSASDTSTVKFKGLEVKCSSV
PMLHRIWSRHGNIIEKTCISNGDIIAKALESLANVVLILEGSTGKTLNDREADYLKSTLS
DLRHMNFNIDWLANSVEKALALHKSKPMVKPLNNLLKVKAQAVEIRFRLMEKLDRVEKEL
DEGIALARRKVPFSEREFEQSLGKGLV
>Sgl34867 E3_activity/RING/RING 30.9 8.4
MKNFYNKLTIILPLISLHYLCVPNVSNAQCCAAVGCSYNDRISIEYPYRLKGVQSDSCGC
QGFDLYCDDEQQGLILELPNAGNFTVGYIFYYSSTKKIIISDPNDCLPQKLLTLDLTTTP
FRGIGQSVDYKLYNCTANAVYNLDRYSDAIIDCLSGSGYTVIGVSSSTIVSDPYCTFLGN
VSIPTEYGFSRGLTTYSRIHLTWDDHGCKSCIDQKTRWGAILGISLSMSIALVLFCYISI
RLYLISRNDSRTSRIINSSATTTTTTENAPTSSGLDQVTIESFPVVVVGESRAVIKHDHM
CPICLSEYSPTDTLKMLPHCLHRFHADCIDVWLQTKPTCPICRTSPSQKS
>Sgl34959 E3_activity/RING/RING 15.5 7.3
MGTGWRRAFCTSIPKNPDSTTTTTNNNTHNTTTSNRSPKLGFTKFNFFSSSSSAPSTPRS
QTPVSELKSLNIRCKISIDETSSSTISPKLKYKNPNINTVTTSSSAPSSPHSPSTFALLL
KNSLRLTKQTRCGVCLHSVKTGQGTAIFTAECSHTFHFPCITTLASKNNGVLLCCPLCGS
QWKEAPFLGTQNKIKIKSTSNNKSTLQSDLRLYDDDEPLAACAASIRFNPIPESEEENDN
GDDDDDNDEFPGFFADPVTPRHQITDANSRGVKVSISPEAAVIAVGRTYETYAVLLTVKA
PPFTARIRRPSVDVVVVLDVGSEMNDVKLHAMKRAMRGMICSLNSNDRLSMVVFSSHTKR
LLPLRRMTPSGKRSARRIIDAINLASEGCSLNDALRKAAKVVQDRKEKSQFASIVLLHGR
DEEKECGSVKTPCLGSSIRFSEIPVHTYKLRESFSDEEFVKSVNIFLSVVVLDVRVQFGL
ACGSAKAEIAAVYSCTGRPCLLNSGAAKLGDLYSSEEREIMVELRVPAASIGSHHMLSVR
SYHKDPSNSKQVIYGGDQSLIVPRPHTIRSSDPKIQRLRGLFVMTRAVAESRRLLGERND
LIGAERLLGSARAVLSQPGLRVTAADEYRRRVDAELAEVKWRRQGQSQGQGQSEEKRRRE
KDGSVQGGGSGSNSGCCLVDEKGEPLTPTSAWKAAERLAKVAMMRKNLNRVSDLHGFEDA
RF
>Sgl34963 ULD/UDP/UBQ/UBQ_Other 34.6 0.0
MSKLDSPVQTQVPVGVFKNPLSGQFHGKQPTTGRRRVFVQTDTGSVLGIELDRSDNVHTV
KRRLQNALNVPTDESSLTYGDMVLKNDLDAIRHDSPLLLTRSNMHRSSSTPCLSPRGGDL
QQKDKSGLIEELGRSDRFCVTKQMVKEIVKGIKNGVEPLLVQSGLGGAYYFRNVRGENVA
IVKPTDEEPFAPNNPKGFVGRALGQPGLKRSVRVGETGIREVAAYLLDRQHFASVPATTL
VKITHSIFNVNDGVNNKAHKKMLVSKIASFQQFIQHDFDASDHGTSSFPVSSVHRIGILD
IRIFNTDRHAGNLLVRKLDGVGRFGQVELIPIDHGLCLPECLEDPYFEWIHWPQASIPFS
EDELAYIESLDPDEDCEMLRSELPMIREACLRILVLCTIFLKEAAASGLCLAEIGEMMSR
EFRSGEEEPSELELVCIEARRLVEERELYVPESEAGEEEFQFDIDCDFPDWDCTPKMAFG
EDYLTRSPGLGMNGRSPLSKLEESLDEEEEESEDGDIEGVRKTDVSSAFPILEKFPSMST
ISMSLKNTSLGEKKFPAMKPENGYSSSGHRSANEQLPASASFVKVADMNEEEWALFLEKF
LELLRPAFDERKSVTLGQRQRQRLGTSCQF
>Sgl34986 E3_activity/RING/U-box 94.2 0.0
MDRIETIDCMNHRVCEWKGLVNYTNSLYLLCISQSNGEVKHDLSIVKPLLALLSEITASI
SSLKIERINFVQIGSYFYRTASAITELHTSVNNSANEAKILQSLSQSSELAKSILVKLQQ
SEKTILDDEVRNMIKQLEEIVNHMGHDLSLIPTSSFIDEEHAEITVCSLSEEMKQAQFDI
SPVQETKINEQQTEPLHPKEHPQEDSIPIGSDLYSFSSMMVSTENSHVKDISQLVETIRS
TSQSSQSSRAKMNNRLSRSVKEVGQHMEPMYKSFICPLTNEIMEDPVTVSSGVTYERSAI
TKYFEEFGDLEEVTCPFTREKLKSKALSPNIALRNIIDEWKDRNDSAQLKVIRAALSIGS
TDSMVLEALKDLQNICQKSPIKKKEVHSLGMMPLLVKLLELRDRVVRCTALEMIRSLVEE
DEAKEEIAKTLAIPTTIKLLSSSYQPIRHAALLLLNDFSKSKLLSEKIGCVTGGILILIQ
TKYNRSIDTFASEAADQILRNMEQCSINIKLMAENGYLKPLLDNLIEGSEERKLEMMTYL
GEIILEDDTKTYVAERISPVLIQMLQNGNPSTRKTVFKALAQISSYPASGKILVEAGIVG
NMVEEMFTKKIYSEPMDSLKDASAILANILESGIEFENLIINSQGHTMVSGYVVFNIIYM
IKNSTPDDLNFNLLRILHSMAKSKKSNAQVISAVKESEASYTLVELVNNPSDDIAVAAVK
LLTLLSSYIGHLLIDRLCKTNGQPEGLIQSASDSSQITERQALSVSFLAKLPHQNLTLNA
ALLSKNTVPEILQSISQIQRNGTRQNRYASMYLEGLVGVLVRFTGTLYDPQMLFLAIDHN
FTAVLTDLLTETSKDEVQILAATGLEKLSAQSLRLSKPPAPSPRNKKQSCNPFRSKSPKK
AKVELCLAHKGVCSEQKTFCLIEAGAIERLLACLDNQNVQVAEAALSALSTLLDDKVDVE
NSVFMLSELDATQRILKAVRIHKNETLWQRAFWMIEMFLVKGGQRPLSLVSQDKLFYITV
VTAFHHGDAYTRQMAENILRYLDKMPSLTGTFNT
>Sgl35042 E3_activity/RING/U-box 105 0.3
MDIAELEESLFAISDAKLHGGMCKLFYNVYCKVLNIFPDLEASRPRSRSGIQALCSLHVA
LEKARNLLQHCSECSKLYLAITGDSVVMKFEKAKCALVDSLRRVEDIVPQTIGCQVQEIV
TELEETMFSLDPSEKQIGDDIIVLLQQGRKFDDSSSDNCELESFHQAACKLGITSSRAAL
AERRSLKKLIEKARIEEDKRKESIVAYLLHLMRKYSKLFRSDLGDDQDSQGSGPCSPTIL
GSSEDGLAGCNGRAFDRQISKINSFNFRPSFSFRTNRRPEQMPIPPEELRCPISLQLMYD
PVIIASGQTYEKICIEKWFSDGHNTCPKTQQQLSHRCLTPNYCVKGLIASWCEQNGVLIP
SGPPDSLDLNYWRLALSESESAQPRSEDSSNSGSIKGVKVLPLESDIAEEYEGNEGECCS
TEQEVSDENVFGKCENYLNVLQGEDDLRFKLKVVEQIRRLLKDDEEARMFLGAQGFVEVL
VGFLKSALAEKNDLALEVGAMALFNLAVNNNRNKEMMLAAGVIPVLEEMIADHDSHGLAA
ALYLNLSCLDEAKPVIGSCKAVSFLINLLVGTSDPQWKLDALHALFNISSCPANISNLLK
SGIINGLVLLLVEPRDHAWTEKSIAVLINLASNNTAKDAITSAPGLVGALASIMDMGEPI
EQEQAVACLLILCNGNDKCCQMVLQEGVIPTLVSIQVNGTARGREKAQKLLMLFREQRQR
DTSPQRVHRSPSVREFNGQVQPEDMKPLSKSISEKVMPGLEQKPLGKVASRRKLGKTFSF
FGKRKNISGPQC
>Sgl35071 E3_activity/RING/U-box 27.1 0.6
MVTENSSKQTPKTNKTPLNQPQNSSENRSNSMSLISPRFKSVAAMAGWDEEALLLASLVV
EDTPERILKEKRNSDLNHKSPLSNSNNNCTSRRKRRRSRVVSIPVLNLEEDDHQQSSNTN
QKEIEKGKIDLPKKIEDEPKEEKEKEESANCSSSSTLACMDRLKDELSCAICLEICYEPS
TTSCGHSFCKNCLKSAADKCGKRCPKCRQLISNGRSCTINTVLWNTIQLLFPQEVEARKA
AAAAAATLSTSSSKAAEERRKGLGARMLNASNHSNNNDSNNVNVSRRTRVSRRLEEVSVS
RRRGVPDQDEDAALALRLQREEFMEIYRSDSSLARDNLRAMARRAMNVRANR
>Sgl35117 E3_activity/RING/RING 26.1 10.9
MWQKQPTKSSYRESIKALEADIQHANNLAASLPRDYCGDSIQMRLSYSPLAPFLIYLIEW
MDYSCTDTLPSFLGLHHILVYKVYVDGMPTMSSQEKRASLREFYAVLYPSLRQLEGNLIE
LEESNKKHRNLDVLSRNKVDDKRKLLDKDLERDDECGICMEPGTKMVLPTCGHSLCIRCF
HDWNSRSRSCPFCRGSLKRVNSKDLWVLTNNHEVVDSVTIARENLTRFFLYIDSLPLITP
DTHLFVYDYMI
>Sgl35119 E3_activity/RING/RING 21 14.9
MEMVYYQLGRSSYQELLKELEADIQHANALVTAIPKPKKGVCLHMKLEYNQLSPLFFLLL
QWLDGSCSCFFPLYFNLFHILIYEVYPDGRTHMPAQGSRATVKEFYAIILPSLRRLHNDL
VEQQSTSHLTKKSNEKKQLIGLQNGIDQEREEECGICLVPTTKMVLPGCCHAMCINCYRN
WNRKSESCPFCRGGLRRVKSEDLWVLTSESEIIDAETVSREELSRFYLYIQSLPKDSSDF
WVYYNYLI
>Sgl35160 E3_adaptor/Cullin_RING/DCX/DWD 106.3 6.8
MNLKNRFCLCSSASAVVEDGGDTTDDSTLSVSPTASPASNMTGHSSLTSHLSLQTLPSVP
SLQFFSLLETSLTVTVTHTLSTSLSLPSSISSLSLSKNLLYVSSGHQINVYDSSTLSLQH
TFNSDGTSTGAVKSIVFYDGKVFSAHQDGKIRVWKLTEKKHKLVSTLPTLTDRLSRFPLP
KNHVKVRRHKTRLWVEHNDAVSSLAVAKNGNIYSVSWDKTLKVWGPKSLRCRESVTAHED
AVNAVAVASDGIVYTGSADGRIRVWAKPEPGTGRGHASVATLEKHKSAVNALALNSDGSI
LFSGACDRSILVWEKEDNAKYMSVSGALRGHDGAILCLINVSDFLISGSADRTVRIWRRG
NEGKYCCLSVLTGHTKPVKSLAAKMEGDDGISVFSGGLNGEIKVWSLKINYTSSNDL
>Sgl35178 E3_activity/RING/RING 8.8 13.8
MFLWLVFLVALAYVVWRSGIITDISGIILYISGIIADIMGNKSSKRSSSSRSMPSYEWNS
YPPSSPYPPQPSYAPHTPHRSHQPEYAPSPSPMPQSYAPPPPSAQPKKTLERKFSRIADN
YRTLDEVTAALAHAGLESSNLIVGIDFTKSNEWTGAKSFNRRSLHHIGNDPNPYEEAISI
IGKTLSVFDEDNLIPCYGFGDASTHDQDVFSFYEDDRSCQGFEEVLSRYRDLVPQLRLAG
PTSFAPVIEMAMTIVEQSGGQYHVLLIIADGQVTRSVDTQPGNLSPQELKTIDAIVQASA
YPLSIVLVGVGDGPWDMMREFDDNIPSRAFDNFQFVNFTQIMSKHMDTSKKQTEFALAAL
MEIPSQYKATLELGMLGRRTGHCPERVCLPPPQYNTAAGRTGSKSFSRTSSFQQNAPPAY
PRSGSGLGTSPSSSTPAYSTPASAPAPTSTSAYESQLCPICITSPKNMAFGCGHQTCCDC
GEFLDACPICRRSIETRIRLY
>Sgl35203 E3_activity/RING/RING 28.3 15.0
MGLSNFPSPAEGVLPILVMNTVMSVAILKNLLRSVLGLIGAVNWVSRENQSSSSSTTTTT
TTEIDQSLSSQPNRGKRMRGVSITQFKCLCNQSCTNSKSESGNGNGNSKFSLEVEVEGRT
TIECCVCLCKFEDEDEVSELSCKHYFHRNCLDKWFDNHHTTCPLCRSIH
>Sgl35209 E3_activity/RING/RING 28.3 15.0
MGLSNFPSPAEGVLPILVMNTVMSVAILKNLLRSVLGLIGAVNWVSRENQSSSSSTTTTT
TTTEIDQSLSSQPNRGKRMRGVSITQFKCLCNQSNTNSKSESGNGNSKFSLEVEVEVEGR
TTIECCVCLCKFEDEDEVSELSCKHYFHRNCLDKWFDNHHTTCPLCRSIH
>Sgl35253 E3_activity/RING/RING 19 4.5
MECLHRFCRECIDKSMRMGNNECPACRTHCASRRSLRDDQRFDQLIAVLYPDIRKFEEEV
MYELEDVDLQKICYEVPPKRKKKSIEMAFYDEDEARNKQIQESITQVLIKQSEALGKKRS
SNKDAAGPSVTRSQR
>Sgl35260 E3_adaptor/Cullin_RING/SCF/F-box 16.9 0.0
MKQKTWPSRSDGSPFTALPLSKSNHHHQPPQSSRNFHSKPPFFLDRPIKSRATTDHRDFS
SLPYDLLTRIASPFSQRDLNAASLVCKSWNDALRPLREAMLLLKWGKRFKHGRAGVGPNM
EKALDSFLKGVARGSSLAMVDAGLVYWEMGRREEGIALYRRAAQLGDPSGLCNLAIAYLQ
ADFANPKEAVKLLLQSSSAGHVRAQYQLALCLHHGRGIDRNLPEAAKWYLRAAEGGYVRA
MYNVSLCYSVGEGFAKSHPQAKKWMKRAADHGHSKAQFEHGLNLFSEGELSKAVVYLELA
SRAGETGASHVKDVIIQQLSTASRDRAMRLAENWRALPSSR
>Sgl35273 E3_adaptor/Cullin_RING/SCF/F-box 16.9 0.0
MKQKTWPSRSDGSPFTALPLSKSNHHHQPPQSSRNFHSKPPFFLDRPIKSRATTDHRDFS
SLPYDLLTRIASPFSQRDLNAASLVCKSWNDALRPLREAMLLLKWGKRFKHGRAGVGPNM
EKALDSFLKGVARGSSLAMVDAGLVYWEMGRREEGIALYRRAAQLGDPSGLCNLAIAYLQ
ADFANPKEAVKLLLQSSSAGHVRAQYQLALCLHHGRGIDRNLPEAAKWYLRAAEGGYVRA
MYNVSLCYSVGEGFAKSHPQAKKWMKRAADHGHSKAQFEHGLNLFSEGELSKAVVYLELA
SRAGETGASHVKDVIIQQLSTASRDRAMRLAENWRALPSSR
>Sgl35331 UBD/Alpha-Helix/UBA 26.8 0.0
MDNDGNSNSTSAKGKEIMIVDPDKDNLLDDYYCWDTDDELEIEYLKETLQIKDTKATSTS
SSSSHKSPKVEYFISMGFKEKDVVQAIKESGEDNDDAILNSLLTYSMQVPENSLGGDPKP
EDDISLDGFSDSDSDTKVLENSHGGDPRPEDDISLDGFSDSDSDIKENGAESDHKDNTIS
ILVDMGYEIEDALIALERCGYETPIEELADFICAAQLAKTADVTEFVAPTRTVKSHEEKK
RKAFPISRVNEWQIKRPIKRERIQRTEESSSRKLMIGYGVPGCMPAVSYRRLPDHLDGPP
YFYYENVAIAPKGVWNEISQCLYGIEPEFVDSIHFSAAARKRGYIHNLPITGRQPLLPIP
PKTIHEAIPDTRRWWPSWDNRTKLNCLLTCIGSAQLTERIRQRLTSGEPSEADKQFVIEQ
CKKWNLVWVGKNRVAVLEPEDMEMLLGFPRYHTRGLSRTDRYKSLGNSFQIDTVAYHLSV
LKTMYPKGLNVLSLFSGIGGAEVALHKLGITLNNVVSVEKENASRKVLQDWWEENGLKGR
LIHFDDVQKVNEAMLDRWMDELNGFDLVIGGSPCNNLAGGNRRTRDGLEGEHSSLFYNYY
YILTYVRESMMKRRA
>Sgl35361 E3_adaptor/Cullin_RING/DCX/DWD 93.2 14.2
MDLLRSYEDEGEENPSLHSQNFESHNNKQLAKNEEDDEEEEEESSMISLPSKSAAPKVDD
TALSLLSSSSSASSKSKPLDPTQHLVNYNPTFDQLWAPIYGPAHPYAKDGLAQGLRNHKL
GFVENAAIDSFVFDEQYNTFHTYGYAADPSASAVNNFVGDFNALEKNRAVSVYNIPQSEQ
KRRRIEKKKGGDEVEEDEEMGVDKEEVENPASESWLSKNKISPWAGKKEGLQGELTEEQK
KYAEEYAKKKAEERGEKVEKGEAVVDKTTFHGKEERDYQGRPWISPPKDKKATNDHCYIP
KRCVHTWSGHTKGVSAIRFFPKYGHLILSAGMDTKIKIWDVYGSGKCMRTYMGHSKAVRD
ICFSNDGTKFLSAGYDKNIKYWDTETGKVISTFSTGKVPYVVKLNPDDDKQNVLLAGMSD
KKIVQWDMNSGEITQEYDQHLGAVNTITFVDNNRRFVTSSDDKSLRVWEYGIPVVIKYIS
EPHMHSMPSISVHPNTNWLAAQSLDNQILIYSTRERFQLNKKKRFAGHIVAGYACQVNFS
PDGRFVMSGDGEGRMWFWDWKTCKVFRTLRCHEGVCIGCEWHPLEQSKVATCGWDGLIKY
WD
>Sgl35368 E3_activity/RING/U-box 94.4 0.1
MIYNLNESTRRMLTFPAVKPSESISITTLFNSLLSITKQISNFNESHFVFTSNKRNAKNA
LRFIQALRVFLEGVRDEGGADKVGKYVISPLLELHVALQKVNFLFEDCTRQDARVWMLMN
AELVSGHFRALIGLVGASLDHALPLLRCDDEVQELGLLLIHQGKRAQFEVQMEDIWASNL
VKFALGRFESRVIPDPSELRRVLSYLGIKKWVDCNNQVKFLEEETGSGSVPAASLMGLMM
YCRCVLFDRIDCDYKRALGKKYSYNSGYLNPDDIKCPISLEIMVDPVTISTGQTYDRVNI
VKWFKAGNMVCPKTGQKIQTIDLVPNLAIKEVIKQYCLENGVLYPIPKYMGSSKRRNNVI
QVVDNLVVQEATRMVADFLSLKLAMGTMGEKSKAAYEIRLLTKRSMFNRACFMESRAISY
LLNLLFSKDSVAQENSMAALLNLSKHPENKPVIVDNGGLSMIIRVLKSGIKMEARYHAAG
TLFYLSSVEEYRGVIGNNPDAIPSLVELVRVGGDQGRKNALVALFSLLLLPSNHCKVLEA
KLVSILVSLLGSVETSEDVIVDSLALLAALAEKPDGARAILHAKALDVITRMLCSPSLDS
SRIGREHLVSLLLTMCINCRGEVVDVLVKNTFLMRALYSLLVEGTSRASKRASSLISILH
EHSERRSVHPMPRALPHENFINVW
>Sgl35396 E3_adaptor/Cullin_RING/SCF/F-box 13.4 0.0
MSNSSIVYHHEAMEHNENKDRLSSLPDDILLSILQLIDIDEATRSSILSRRWRYLAPYSY
FTSLDLDANKKKALVGYKNCPISYKDGKPKFVNWVNQLVTLHRAPFLNDFRVCFPLLESD
SDCLCMWIRFAISKGVKKLELVFCSSGGFDYSGSLPLTPRCSFPSNVFKVDNNNNNNVFS
NNLLTSLCLRFVNISGELLELVLSRSHLLERLYIEGSNDLVNLKINNTSEKLKHLSIHRC
NFLQEIAIHAVNLVSFELSHSHKDLARFRPDSVKVVYASVPSLVDARFYWLDYYTFFPYF
SQMHGFAAQLTKLSLEMNMRVSREPNLPSFSNVKSLELRVTFGHHSFDWRHMNPLRLRRY
VKACPILEYIKLQVNWSCDCDRRQCEKELQLSDFESDDSDFELDDDFDMDSGSDEYEYSL
EDVRQWLERKEEEGFNGTLPFLRKIEWTAAFSNHFEAEYQLALYLIKNAVNLEKFICDPR
YHVNWSHHEAMIFKDDYFEDVCRLRATKLAMVIPSSVDFTIL
>Sgl35398 E3_activity/RING/RING 32.7 9.1
MTLLWCDIFIPVFKDKNYIYFLGFSSTMSLVESPSSSSLNNHDFFQRDTTSQSPESSSNS
GGKISPAILFIIIILAVIFFISGLLHLLVRFFIRKRSSSSSSFSQSNRYPDNISTSEGIQ
RQLQNLFHLHDSGLDQAFIDALPVFQYKEIVGLKEPFDCAVCLCEFSEQDKLRLLPLCSH
AFHIDCIDTWLLSNSTCPLCRGALYTPGLAIENPVFDFDESREDDTGGGGDCNGHHKGVE
IEIVSEKSKRVFPVRLGKFKSTSNSNINNSEVVHEQVLQRDVGETSSSNLDARRCFSMGS
YQYVVADSVMQVALCPNRPSNGGAESKIIKGRGGQNGNFTCNIRDDDDDVEARKINNIGT
KNESLSVSKIWLWSKKGKFPNSTNATDFSSGFPVDMNLPWTNRGQAT
>Sgl35407 E3_adaptor/Cullin_RING/DCX/DWD 27 10.4
MFVKKFVEKAIKKPGETLESLKPEDVDPRLAFHYGLPSSAAMLAYDPVQNILAVSTKNGQ
IKLLGKDNTQALLESNDMQPSKFLQFIHNQGILVNVTFKDQIEVWDIDRKMLLHVHDFNE
EITSFSIMQHCFFIFIGDSGGNVTVWKINKELSQFEKMNYWIPASASYGYTNKDAVDHAV
MYILPQPTLETKRILIIFSDGLITLWDIPESKAVFTTVGNEAMTHLASHESKRVTAASWV
CPFGSKVAVGYDTGDILVYTIPNSSLSRDSGNTQNVHTSYKINLGYRLEKTPIASLKWVF
SDGKVNRLYVLGASDATSTNLVQVILLNDDTESRTTKVGLQLPEPCHKLEIISSLKDQSK
HKQQFLLLIGISGLMYAYDDHSVEKSLLQSQSKSSVSLPSELIIKLPFSDSKITSAQFIT
NQSSNIDFKQEDYMVIAKTIPCVLPSEAKNISSPHFTGFSKVTNLYITGHNDGTIKFWDV
TCPLLIPLLSLTQQNEDDSSQSDIAVTAIQYCSALRLLFSGDKSGMVRIYQFKPEPFSIE
NAFFSLQGSTKKGNNHIIHSVKFIKVNASVLSFSINSSSKYLAVGSEQGHISIIDIESSS
ILYQKQIGTELSSDVMSLKFETSDNHGFEKNILVIATRDSSLLALDADTGSTLSSSAVHP
KKPSKALFMQTLETTSGSSTEEATQKQQLLLCSEKAVYIYSLPHIVQGTKKIFYKKKFHS
SSCVWASTFCSSSSTGLILLFSCGKIEIRSFPELSLVKDTTLKCFTCLPMKPNTLPDYFI
CSSADGEVIMMRSDQEVAVASMFLQNDKYRHLDSLSRVYDKHLTTLEDSSTSLSVHHKEK
KKGMFSNLFKDVTVSKTNHGADNEAADGKESYEELSNNLAVSNFPTQVEAPANSAPADRA
LETENVDMDIDDIDLDDQDEKPKGQNMIAMLNKQKLASRFNSFKGKLKQMTAKNEKPSTH
EEPQIEKTETQAVDQIKKKYGFSSSSTNTESNIAEQTKNKLMENVKKLQGISLKTTEMQD
NAQTFSSMAKETLRLAEQKNSPSKT
>Sgl35474 E3_adaptor/Cullin_RING/SCF/F-box 15.1 0.0
MEEELAMLRQLLSNFHELSQLYGYHTSSSFHPHLFSQSSSRCCILNLDDNLVEENYNSVI
MAAENPGILKMVDLYKPPPAKKSRKERSRGKQCRSSNSSENMSQELWKDFPDDLLEVVIA
RLPIASFFRFRSVCQKWNSLLASRSFLEHCSQVSQSQPWFYTITHENVNTGAIYDPSAKK
WRHPTIPSLPPKVILLPVASAGGLVCFLDLGHRYFYICNPLTQSWKELPERSVKVWSRVA
VGMIRYGNSAAGGAYKILWFGRDGEYEIYDSMKNSWARPGILPSNIKLPLSLNFRSHTVS
IESTIYFLRSDPEGIVSYDLESGIWKQYLIPTPPNSTDHNLAECGGQIFLVGLLTKNAAT
CVCIWELQKMTLLWKEVDRMPNVWCLEFYGKHVRMNCLGNKGLLLLSLRSRQMNRIVTYD
VAKRDWLKVPGCVLPHGRKRQFIACGTAFYPSLTAVP
>Sgl35596 E3_activity/RING/RING 11.5 9.4
MKRQLTLLTPFHSFIHLSLSIFISVKSFFFLFLSPNFGLSFLSLTNFNQQFTIVNFSPTQ
FLLHFRDFNNLKNCTEWLEMGEHLVLDVDRFVEHTSVQEQAEVASSSSSNSRLEGKKEED
VNEGEGGEDEPLIQMAECRICQEEDGISSLEVPCTCSGSLKYAHRKCVQRWCNEKGDITC
EICHQPYQPGYTAPPPAPQPEDASIDIGGGWTISGTPLDLHDPRLLAIAEAERQFLEAEY
DDYAASSASGAAFCRSAALILMALLLLRHAWTVPDSDDEDDMSAFFSLFLLRAAGFLLPC
YIMAWAISILQRRRQRQEAAALAATQVAFVLQSGQRRGLQFMIAPRSPSAVADEAV
>Sgl35616 E3_activity/RING/RING 33.8 5.5
MASESETEMQSMLERLISSRNRDLSTFLPLLFGIDPDPTHEVSGQNTGNPDHNTGNHSDP
DDQSQHQRDRIVLINPLTQGMVVIEGAGFDSLFRGLQSKDGQPPASKSAIEAMPSVEITE
DDQGQECVICLDGYEVGKSVKEMPCKHRFHGGCIEKWLKLHGSCPVCRFKMPIEEGGGGK
KSDENDDGDRMIGEREVWVSFTIGGSRRRRSSDENGNNTEDGNGNGSISGDLGNGSSEME
>Sgl35632 E3_activity/RING/RING 24 3.4
MGSHEPYWRTNTSFSPPPSRWDYGFQSEGIHYGSSESIQLFGSTSSNSKESRSWIRGGYH
PSHQYSASEGGAQYFSSPSDASLIQPWTPPPIRRISIDGFETSARRDTISGPLSFTPTME
GTSMVRDGGGFTSPHSDGSEFEHTAKLNLSTPRNFPSRRSFMSKPVHPLSFPVHSFTREA
SASPAAGFSAYDAATPQRDTHRLSSGSSSIDLTDISERLEPEFLARSSNVSEGFKCGLCD
RNLSQRSPWSSRRIVKSEDMPVAAVLSCRHVFHAECLDQATPKSHKSDPPCPICSKQEKE
HSPEQHIFPRLRNHLPRLRAFSEEGSSRTWSCVQAGDCVEGALHTPQKSSMLLLNRHKIK
KSLSHKGNSGKDFPGKLKKTSSNPLHLFGGKFLDHGAGGCSKTAAGPSNKKG
>Sgl35679 E3_activity/RING/RING 11.8 9.4
MKRQLTLLTPFHSFIHLSLSLSLYSFLDFNNLKNCTEWLEMGEHLVLDVDRFVEHTSVQE
QAEVASSSSSNSRLEGKKEEDVNEGEGGEDEPLIQMAECRICQEEDGISSLEVPCTCSGS
LKYAHRKCVQRWCNEKGDITCEICHQPYQPGYTAPPPAPQPEDASIDIGGGWTISGTPLD
LHDPRLLAIAEAERQFLEAEYDDYAASSASGAAFCRSAALILMALLLLRHAWTVPDSDDE
DDMSAFFSLFLLRAAGFLLPCYIMAWAISILQRRRQRQEAAALAATQVAFVLQSGQRRGL
QFMIAPRSPSAVADEAV
>Sgl35715 ULD/UDP/UFD/PB1 60.2 0.0
MSPPLLGVEGGGQSNDHPLVPSPTCTESGLKEHNYFGLSECSSVDSSNVSSLSEDNKGSL
NFKATELRLGLPGSQSPERDSDLCLVSASKLDEKPLFPLTPLKDGISSSSEKAAVSGSKR
GFSDTEHNWALKSSAHDTEAPKSVAQGKLPANDGVNVMLASRPGPPQAPPKSGAPQAPQK
ALGELPRPNSSNNAPAAKAQVVGWPPIRSFRKNTLATTSKNSEPLFVKVSMDGAPYLRKV
DLRTYTTYQELSSGLEKMFSCFTLGQCGSNMSETKLRDLLHGSEYVLTYEDKDGDWMLVG
DVPWEMFTESCKRLKIMKGSDAIGLAPRVMEKSKSRN
>Sgl35730 E3_adaptor/Cullin_RING/DCX/DWD 52.7 3.9
MSGNCLNFEEPIKDAITRLRFAPTSNNLLISSWDYSIRLVDVNTGKLRLEAQTEAAVLDC
CFEDEFAAFSAASDGSIFRYDLESGAYDIIGKHEDSATCVEYSPEISKLITGGWDGKVLS
WDMRSAKASQSVIYSNLHVESVSVCGIELLMTTGTSVRKYDLRKLNGAIQAEDLSMGFWI
RCVRSMACQKGFAVGSVDGHVTLQSDSDGMGYTFRCIPKSKKGKYHLVTVNDIAFSPSLP
GAFVTGDYEGYVIAWDGSSRKRLLELPRYPNSVASLSYNHTGELLAIASSYTYQEANERE
DNPQIFIQKLGESCLKSASYGSSSRR
>Sgl35749 E3_adaptor/Cullin_RING/DCX/DWD 52.7 3.9
MSGNCLNFEEPIKDAITRLRFAPTSNNLLISSWDYSIRLVDVNTGKLRLEAQTEAAVLDC
CFEDEFAAFSAASDGSIFRYDLESGAYDIIGKHEDSATCVEYSPEISKLITGGWDGKVLS
WDMRSAKASQSVIYSNLHVESVSVCGIELLMTTGTSVRKYDLRKLNGAIQAEDLSMGFWI
RCVRSMACQKGFAVGSVDGHVTLQSDSDGMGYTFRCIPKSKKGKYHLVTVNDIAFSPSLP
GAFVTGDYEGYVIAWDGSSRKRLLELPRYPNSVASLSYNHTGELLAIASSYTYQEANERE
DNPQIFIQKLGESCLKSASYGSSSRR
>Sgl35814 E3_adaptor/Cullin_RING/DCX/DWD 107 23.9
MKLLQCHFDDDSQSSNSNSFRSGYSSSSSSSSSSLTSQRSLQSLPSLSSPESQLDQKNNI
YYQCISTLKGHTSYVFSLVLHGKHLYSGSSNEEIRVWPREQTLTTHYQNQNNDNNNNNNN
NNNVVATSNGAVKSLVAWGDKLFSAHQDHKIRVWKIDNNNNSNSSSNNNNNNNNNSNNNS
NSQKSYQCVATLPTMNDRFSRLFSAKNYIKVRRHKSCTWVHHVDTVSSLALSADGSLLYS
ASWDRSFKVWRTSDFKCLESVSNAHDDAINAITTSPDGFIYTGSADKTIKVWKKNHQTGA
TNHSLVATLKRHKSAVNALALSKDGSVLYSGACDRSIVVWAKDNSLNQSESGGDDEDDHM
VVVGALRGHTKAILCLTVVSDLLCSGSADNTIRVWKRTDDGGGDKGYTCLAVLQGHTKPV
KCITAMVDPKCSSDSGTCYLIYSGSLDCDIKVWKIWVPFQ
>Sgl36035 E3_activity/RING/RING 12.4 0.1
MEFLELAKETQIEGKTRCPCNKCKLSKWLPVNDVGGHILFHGFYKIIENWIFHRVGEESN
IHQSLGEQSNVIGRDDMEGLLKSMFRANNPHSIHEPIEDPFDESDFREDGLHDIDVESGV
AHEDDDCDEFQYENTNEEAKFRRLMDASQEALYEGCSTFSKLSFLLHLFHLKCLYHWSAE
SFTKLLELLIDAFFQIKEFPSSY
>Sgl36083 E3_adaptor/Cullin_RING/Cullin 741.3 4.8
MERWNSPLNRLPSPSSLPLKHLSEGETRMSNQKKKQFQIEAFKHKVVVDPKYADKTWRIL
EHAIHEIYNQNASGLSFEELYRNAYNMVLHKFGEKLYLGLVGTMTAHLKEISKSVEIAQG
GSFLEELNRKWTDHNKALQMIRDILMYMDRTFVPSTHKTPVYELGLNLWRDNVIHSSNIQ
TRLLNTLLELIQKERTGEVINRGLMRNIIKMLMDLGASVYQEDFEKPFLEVSANFYRVES
QEFIECCDCGDYLKKAERRLNEEIERVSHYLDLRSEFKITKVVEREMIANHMPRLVHMEN
SGLVNMLLDDKYEDLGRMYSLFRRVDNGLGTIRDVMTSHIRETGKQLVTDPEKVKDPVEF
VQRLLDEKDKYDKIISLAFTNDKTFQNALNSSFEYFINLNTRSPEFISLFVDDKLRKGLK
GVSEEDVEIVLDKVMMLFRYLQEKDVFEKYYKQHLAKRLLSGKTVSDDAERSLIVKLKTE
CGYQFTSKLEGMFTDMKTSQDTIQGFYANHGAELGDGPTLVVQVLTTGSWPTQPSVPCNL
PAELSLLCEKFRSYYLGTHTGRRLSWQTNMGTADIKAIFSKGQKHELNVSTFQMCVLMLF
NNADKLSYREIEQATEIPAPELKRCLQSLACVKGKNVLRKEPMSKDIGENDVFLFNDKFT
SKFYKVKIGTVVAQKESEPEKQETRQRVEEDRKPQIEAAIVRIMKSRKVLDHNNIIAEVT
KQLQSRFLPNPVEIKKRIESLIEREFLERDSADRKLYRYLA
>Sgl36393 E3_activity/RING/RING 17.9 4.5
MECLHRFCRECIDKSMRMGNNECPACRTHCASRRSLRDDQRFDQLIAVLYPDIRKFEEEL
MYELEDVDLQKICYEVPPKRKKKYFVLNDYFFAQIQESITQVLIKQSEALGKKRSSNKDA
AGPSVTRSQR
>Sgl36432 E3_adaptor/Cullin_RING/DCX/DWD 59.5 11.9
MAQFQLSETYACVPSTERGRGILISGDPKSNNILYCNGRSVIIRNLDNPQKVEVYGEHAY
PVTVARYSPNGEWIASADVSGVVRIWGTHNGFVLKNEFKVLSGRIDDLQWSPDSLRIVAS
GDGKGKSLVRAFMWDSGSTVGEFDGHSRRVLSCAFKPSRPYRIVTCGEDFLVNFYEGPPF
KFKHSQREHTNFVNCVRFSPDGSKFITVGSDKKGITYEAKTGEKLGELSAEDGHQGSIYA
VSWSPDSKQASVAVLTVSADKTAKVWKISEDGNGISIKTLTSGSGGVEDMLVGCLWQNDH
LITVSLGGVINVYSASDLEKGPLTLSGHLKNVSALIMFKSDESMVLSCSYDGIIIKWIRG
VGYSGKINMKDHAPIKCFAAVEGEIILSGFDNKEHQLFVNGNKCEFARNSSEEEEEECRT
EDKREEEEEEKKDICIERLM
>Sgl36433 E3_adaptor/Cullin_RING/DCX/DWD 65.9 2.5
MYPSPYQCNLACTHASTKCTPFKALYGREPPSLLRLPKGGVVVSAVDELLEERDAILDDL
KANLLRAQQRMKNQEDEHRREVKYEVGDWVYLKLQPYRQQSLAKRPYEKLSARYYGPYEI
IERIGEVAYKLQLPNSAKIHPVFHVSLLKSAVGDAHTSPDLPKQLNEEMELEVQPESVLN
IRVTSGDHQEVLIKWDGLPEFDATWEDLEAVKRKFPRFHLEDKVAVLAGGNATPPQDGPA
QQRPVVKYTYARRNSRKGKSVWRAPIQEDDCGPAEHVDVGSQPKDLSVAINAPEVVLVAT
DSGAVLLNGLKVLSSVELGFTVTACALSPDGTEAILGGQDGKLHIYSVSGDALTEEAVLE
KHRGAITVIHYSPDVSMFASGDANREAVIWDRSTREVKLNNMLYHTARINCLSWSPDNTM
VATGSLDTNVIIYELGKPASSRTTIKAAHLGGVYGVAFADEHSIVSSGEDGCVRQWTITS
E
>Sgl36486 E3_activity/RING/U-box 117 0.3
MEESLITTTPTTPSTTTEVKETRDPPSISMDGELAQNIHLVISDIGKISTNGGFCDLFKK
DCNDLGRRISLLSYLVDEICDSSSPSSSSSQSHSDNNNDEDYDDDSSSNSCFVDLFVALQ
DSKRLLLAASSFDPNEDGATKRVSFQFQCVTWKLEKALGNIPYEQFGISEEVQEQVELVR
TQLKRATERYGPLNSSKIIRAASQPLLNELELLQSGNKGFGCLHLDNTGNIDHEVRRKVK
TSRSGNSSTSDSHDVSERVELSSVAVPECVSSSVEEEDGCSGETEEESMKPDSVSIPEDF
LCPISLEIMRDPVIVSTGQTYERSYIQRWIDSGNMSCPKTQQKLQHFTLTPNYVLRSLIY
QWCAKNNIEQPTALMTGKIKKSDGTFRDVSGDIAAIQALVRKLSSRAVEDRRTSVAEIRS
LSKRSTDNRILIAEAGAIPVLVNLLTSDDELTQENAVTSILNLSIYEHNKELIMLAGAIP
SIVQVLRNGSMEARENAAATLFSLSLADENKIIIGASGAISALVELLQSGSPRGKKDAAT
ALFNLCIYQGNKGRAVRAGIIAALMKMLTESSGTMVDEALTILSVLAGHQEAKVAIVKAC
TIPVLIDLLRTGLPRNKENAAAILLALCKRDMENLVSLGRLCAAVPLTEITKNGTERAKR
KATSLLELLRKHQQQS
>Sgl36672 E3_adaptor/Cullin_RING/SCF/F-box 12.3 0.0
MVEKKWTTLQSRKHHCNEANDLFTRLPDDLLLFIMSFLTMKETARTSVLSRRWNYLWRCC
PVLIFEDSSAMKRMFAHYIVVPLERSRFLRRVNGVRERHVGGYVHELRVTFDLNKTALLP
I
>Sgl36945 UBD/UBC-like/UBD_UBC 109.6 0.0
MKLCPREVEKLALHNAGFLAQKRLASGLRLSYTEAVALIATQVVVHSEKFYNFRSSVFID
FEFCSCWKQECGGTDGHWKEASWKGPSETPYDGGVFQLAFAVPEQYPLQPPQVRFLTKIF
HPNVHFKTGEVCLDILKNAWSPAWTLQSVCRAILALMAHLEPDSPLNCDSGNLLRSGDLR
GFQSMAKMYTRLAAMPKKG
>Sgl36987 E3_activity/RING/RING 12.6 9.5
MGANSSKEETISSSPTWNNQYGNQQPGYSEPYYVPESQYHHQPVQQPYPPAQTSTPTPTY
AGPTHEHNKRFERMYSRIADEYSSLEQVTQALARAGLESSNLIVGVDFTKSNEWTGAKSF
NKRSLHHIGGYGDGPNPYEQAISIIGKTLAAFDDDNLIPCYGFGDASTHDQDVFSFYPDE
RICNGFEEVLSRYREIVPHLRLAGPTSFAPVIEMAMTIVERSGGQYHVLLIIADGQVTRS
VDTEHGRLSPQEQRTVDAIVEASKYPLSIVVVGVGDGPWDTMKEFDDNIPARDFDNFQFV
NFTEIMAKSTHPTRKETEFALAALMEVPLQYKATIELHLLGQRRGTSPERVPLPTPMYNA
PSQINTAPSFNYPMPSDSTSFQSSAPSLNYSMPSHSTSFQSSAPSFNYSMPSHSTSFQSS
APSFNYSMPSHSTSFQSTAPHYYENYSHASTAPPVPSSNYNSDPPDASSDYDNQLCPICL
SNKKDMAFGCGHQTCAECGQDLLNCPICRSTIQTRIKLY
>Sgl37092 E3_adaptor/Cullin_RING/DCX/DWD 54.1 4.7
MGATSDPSTNPEPVSDEQQKQRSEIYTYEAPWHIYAMNWSVRRDKKYRLAIASLLEHSLN
RVEIVQLDDSTGEIKSDASLSFDHPYPPTKAIFIPDKDCSKPDLLATSSDYLRIWHINQD
SSSNSSKVELKSLLNGNKNSEYCGPLTSFDWNEAEPRRIGTSSIDTTCTIWDIERETVDT
QLIAHDKEVYDIAWGGAGVFASVSADGSVRVFDLRDKEHSTIIYESSEPDTPLVRLGWNK
QDPRYMATIIMDSPKVVVLDIRFPTLPVVELQRHQASANAIAWAPHSSCHICTAGDDMQA
LIWDLSSMGQPVEGGLDPILAYTAGAEIEQLQWSSSQPDWVAIAFSNKLQILRV
>Sgl37117 E3_activity/RING/RING 20.7 15.6
MSILPSHTQGSESSSSSFSSQNPNLINHGFSTIHQHNQPQHSQVSSSTPHLSSLRISDHQ
PSGSIPNSGSMAEGGANSSGSSKKVIGFEGSNGKKTSPNHNSSNSRVQAHSVVEGGVGSP
QFGGEIGSSPPNSRASGSARRRYQAVSGNHLLNFQYTPISRSQPRGPPPKKPQKIKPYNK
DLFLQANYKFVVLDSGNYTVESMDPDKTLQWEDIICLRYSTPHPIQCPICLDSPLCPQIT
ACGHIFCFPCILQYLFMGEENHKAECWRKCPLCFMMISSRDLYTIYIENVREHNVGDVLD
FMLLSRGKNSFSLHEKLQGGESTKSCDSFSKFILTLDVDLSVREAISELDNWIARADSGL
VDDLEKIPYVCAAMEHLKQRKKYWNARRRLGGSKSCENNDGDTVDDLIPSCKDDEIGNGT
LSPAANDANKGTSHVMTDVVHGGVCLVQSSDTDESVEGHDVSLSSSYDESKTLRTNASLD
TKEKELYNFYQAIDGQPIILHPVNLKCLLHHYGSYDLLPARLSGKILQLESMTQSEATRR
RYRYLSHFPLTTTFQLCEIDFKDILPAEALSPFMDELKKREKQRKQLARKEHQDKIKAEA
VAAYSLPFPYNTMQSSCDTPTFSMDDFEALGSPVTTVASSPPVQGRQLFSNVARLGFAAG
CDSPSLNIPETTTEASIGRTSSSYASNGSTNQGACSFANVISREKSSESVTRKANEAGKK
GKKPSRVLLSTAGGRRY
>Sgl37130 E3_adaptor/Cullin_RING/SCF/F-box 12.2 0.0
MMNYFPEEVLEHIFDFVTANQDRNSVSLVCKTWFKVERESRSKVFIGNCYAISPERLISR
FPRLKSLTLKGKPHFADFNLVPYDWGAYVYPWIEALAKGCPSFEELKLKRMVVTDESLEL
LSKSCLHFKSLVLVSCEGFTTDGLAAIASNCRYLRELDLQENEVDDRKGHWLSCFPENST
SLVSLNFACLKGEVNLAALERLVSRSPNLKSLRLNRAVPFETLQKILSKAPQLSDLGTGS
FIHDPKSETFNNLKNVVSKCESIKSLSGFLEVAARCLPAIYPLCSKLTTLNLSYAPGICG
FELTQLILQCKKLQRLWILDSIGDKGLAVVADTCKELEELRVFPSDPFAPGDAAAVTEEG
LVAISCGCPKLNSVLYFCHQMTNAGLITVAKNCPNFTRFRLCILDPIKPDAVTGEPLDEG
FGAIVQSCKQLRRLSISGFLTDKVFLYIGMYAKQLEMLSVAFAGDSDDAMINVLSGCKKL
RKLEIRDCPFGNLALLTDMGKYETMRSLWMSSCQVTLGACKLLAREMPQLNVEIIDENEQ
GDFNLDDDRQKVEKMYLYRTLVGPRKDAPEFVWTL
>Sgl37156 E3_adaptor/Cullin_RING/SCF/F-box 15.3 0.0
MESNCCIFPDDLVEEILSRLPVKDLLRARCVSKRWSGLIDDVSFVKKHYQVQYSVPRLDE
NMTYFVDHFNRQDLYSVEFQLLSILHQGDAALPLTVDLTADLRRDSNAALPFGRDQYYQC
VGCVNGIICLFCESRNTLQAEDCFFALWNPATREFKTLPYPNDPCPTNYCQFQTDGFGFD
PSSSDFKILAGYIDRNDPYSLEHYQMLYSLKSNSWKWISNPPDPAHDVLPQGYFDRYLNG
VCYWVTGLHEEASGCPTNSVIVSFNFIAEVFKVSELPPDALSLVSESGGPYDQKLMLYKE
RLALAMSFKVREEASYDIHLWGATQLDDYGVPLSWQRLFTIRPTPAKFGLYADTMLMNGD
FQLVCNYGDGDSDTESYLYIHSSGELKKFDIWWKAWFRYVESLFPLSCKRQLVQT
>Sgl37182 E3_activity/RING/RING 30.4 10.5
MEFYSYPSQQIATSSSILCNLGEKIRGTLSFALSATLGSLFSAIFTFCFALVGTLLGAMT
GALIGQETESGFVRGAAIGAISGAVFSIEVFESSVVLWRSDESGIGCLLYLIDVIASLLS
GRLVRERIGPAMLSAVQSQMGAVETNFEDVTNIFDTSEVKGLSGDLVDKIPKIKITNKNN
IDASGERVSCSVCLQDFQIGETVRSLPHCHHMFHLPCIDKWLLKHGSCPMCRRDM
>Sgl37215 E3_adaptor/Cullin_RING/SCF/F-box 19.4 0.0
MSDLPFEIVRDILLNLPAKSLLRFKSVCKLWYEMINDPNFMKLHYEQSNLHIVFRNPTFH
ICDFDTFDNAVELDYPFKYLDDGYDKDSFLKGVHEWGSSCGLFCFTMDYCCPYTIILYNP
TTRTHKTLPFLAIEPPFHADRLNYLGFGYDHVSDDYKCVRILQDDEGSFSSQVMVYSLRT
DSWRRGAQDVPHFFQCHYEYYIDFKGILHWSAEGDNRTLPPIVAFNLSDETFSSVSLPNY
DTEVYTFSHIGVLDDCLCLMLNDLHHCDVWIMKEYSVTASWTRLFRLANKLNNFDLSPIS
FINRRKQLLVSYSSFKVFTVDLETLNITDFKLPGYRRIWTAYVCPENLLMFKDAENGLGG
IRQVWKKSVKRQRVMRLANRSLQQFASMLEEYEQPHSSNAGSLS
>Sgl37216 E3_adaptor/Cullin_RING/SCF/F-box 19.5 0.0
MSELPIEIVRDILLNLPAKSLLRFKSVCKLWYEMINSPNFMKLHFEQSNLHIVFRNPTFH
MCDFDTFDNVVELDYPFKYLDNDYNKDSYHKADKGVYEWGSCRGLFCFTTGYCQPHTIFL
YNPTTRTHKTLPFLAIEPPFHADRMNFLGFGYDSVSDDYKCVRILQHDHDDNDYEYKCVR
IVPHIDDDDEEEVEYFCPSQVMVYSLRADSWRQGAQDIPYYFRCQNEYYIDFKGILHWSA
EDDNRRLLPIVAFNLSDETFSSVSLPDYETETFTFAHIGVLDDCLCLMLNDLGHCDLWIM
KEYGVLASWTRLFRFAKEQTSFHFSPISFINRRKQLLVTYSSFKVFTVDLETLKITDFKL
PGYRRIWNAYVCPENLLMFKDAENGLGGIRKKNAKHRRLMRLA
>Sgl37280 E3_activity/RING/RING 12.7 9.5
MGANSSKEETISSSPTWNNQYGNQQPGYSEPYYVPESQYHHQPVQQPYPPAQTSTPRPTY
AGPTHEHNKRFERMYSRIADEYSSLEQVTQALARAGLESSNLIVGVDFTKSNEWTGAKSF
NKRSLHHIGGYGDGPNPYEQAISIIGKTLAAFDDDNLIPCYGFGDASTHDQDVFSFYPDK
RICNGFEEVLSRYREIVPHLRLAGPTSFAPVIEMAMTVVERSGGQYHVLLIIADGQVTRS
VDTEHANPLSIVVVGVGDGPWDTMKEFDDNIPARDFDNFQFVNFTEIMAKSTHPTRKETE
FALAALMEVPLQYKATIELHLLGQRRGTSPERVPLPTPMYNAPSQINTAPSFNYPMPSDS
TSFQSSAPSLNYSMPSHSTSFQSSAPSFNYSMPSHSTSFQSTAPHYYENYSHASTAPPVP
SSNYNSDPPDASSDYDNQLCPICLSNKKDMAFGCGHQTCAECGQDLLNCPICRSTIQTRI
KLY
>Sgl37310 UBD/UBC-like/UBD_UBC 113.3 0.0
MVGIPSNELLFHCREAESLKKPFTPLREVHVQVTHSMPPEKIEIFKSLEGWAEQNLLGPS
ETPYDGGVFQLAFAVPEQYPLQPPQVRFLTKIFHPNVHFKTGEVCLDILKNAWSPAWTLQ
SVCRAIIALMAHPEPDSPLNCDSGNLLRSGDLRGFQSMAKMYTRLAAMPKKG
>Sgl37596 DUB/USP 146.5 0.4
MICRCSSFDATGSQQYAGLLGRGTPWMKSIACSMPRSDWSSLCSSSGKTSANSVSNDKRC
SLVGAMVGCLENYVPIEHLTSKLDALNARLDARPLSFSRPSDDSATKYTKLDERNNKLED
FTGICSPEEYLEWERQVDKLADIKELDDSQTFKIGFLRLTKHACLWFDGVKAKRKRQDKP
KINTWSQLRKKMRDKYVPYDFDQQNYLRLTSLFKGPMTVIEYIAEFERLTLLIEGALKSF
TKVESIEVTENFLCDNCKEKVKVEKQLILDQAPSVVGLHLKRFKSDGIYVEKIDKKVEFP
LELDLGPYTKGSNDGHEDLKYELFAVVVHVGFSSTSGHYFCYIRTSPEKWYRFDDSKVTM
VEEETVLDQHAYTILTA
>Sgl37776 E3_activity/RING/U-box 117.6 0.3
MEESLITTTSTTPSTTTEVKETRDPPSISMDGELAQNIHLVISDIGKISTNGGFCDLFKK
DCNDLGRRISLLSYLVDEICDSSSPSSSSSQSHSDNNNDEDYDNDSSSNSCFVDLFVALQ
DSKRLLLAASSFDPNEDGATKRVSFQFQCVTWKLEKALGNIPYEQFGISEEVQEQVELVR
TQLKRATERYGPLNSSKIIRAASQPLLNELELLQSGNKGFGCLHLDNTGNIDHEVRRKVK
TSRSGNSSTSDSHDVSERVELSSVAVPECVSSSVEEEDGCSGETEEESMKPDSVSIPEDF
LCPISLEIMRDPVIVSTGQTYERSYIQRWIDSGNMSCPKTQQKLQHFTLTPNYVLRSLIY
QWCAKNNIEQPTALMTGKIKKSDGTFRDVSGDIAAIQALVRKLSSRAVEDRRTSVAEIRS
LSKRSTDNRILIAEAGAIPVLVNLLTSDDELTQENAVTSILNLSIYEHNKELIMLAGAIP
SIVQVLRNGSMEARENAAATLFSLSLADENKIIIGASGAISALVELLQSGSLEERKMLPQ
HFLTCAYIRVTRAGQSELVSLQH
>Sgl37786 E3_activity/RING/U-box 117 0.3
MEESLITTTSTTPSTTTEVKETRDPPSISMDGELAQNIHLVISDIGKISTNGGFCDLFKK
DCNDLGRRISLLSYLVDEICDSSSPSSSSSQSHSDNNNDEDYDNDSSSNSCFVDLFVALQ
DSKRLLLAASSFDPNEDGATKRVSFQFQCVTWKLEKALGNIPYEQFGISEEVQEQVELVR
TQLKRATERYGPLNSSKIIRAASQPLLNELELLQSGNKGFGCLHLDNTGNIDHEVRRKVK
TSRSGNSSTSDSHDVSERVELSSVAVPECVSSSVEEEDGCSGETEEESMKPDSVSIPEDF
LCPISLEIMRDPVIVSTGQTYERSYIQRWIDSGNMSCPKTQQKLQHFTLTPNYVLRSLIY
QWCAKNNIEQPTALMTGKIKKSDGTFRDVSGDIAAIQALVRKLSSRAVEDRRTSVAEIRS
LSKRSTDNRILIAEAGAIPVLVNLLTSDDELTQENAVTSILNLSIYEHNKELIMLAGAIP
SIVQVLRNGSMEARENAAATLFSLSLADENKIIIGASGAISALVELLQSGSPRGKKDAAT
ALFNLCIYQGNKGRAVRAGIIAALMKMLTESSGTMVDEALTILSVLAGHQEAKVAIVKAC
TIPVLIDLLRTGLPRNKENAAAILLALCKRDMENLVSLGRLCAAVPLTEITKNGTERAKR
KATSLLELLRKHQQQS
>Sgl37857 ULD/UDP/UBQ/UBQ_Other 24.7 0.0
MAGEKESPSPLLPETEEEITLIVKWSGKEYTVRVCGDDTVAELKRRICEATNVLPKRQKL
LYPKVVGPKLSDDSTLLSNLPLKSSVKMTMIGTVEDDLIIDPIDSPEILDDFELGQDEAV
DIKDKEVNKQKLRRRIDQYKIEVRNPCRTGKKLLVLDIDYTLFDHRSPAENPLQLMRPYL
HEFLTAAYAEYDIMIWSATSMKWVELKMGQLGVLNNPNYKITALLDHLAMITVQSESRGI
FDCKPLGLIWEQFPEFYSSRNTIMFDDLRRNFVMNPQNGLAIRPFRKAHANRESDRELVK
LTQYLLSVAELDDLSILDHRSWESYMEDNSKRRRRA
>Sgl38029 E3_activity/RING/RING 32.5 6.6
MKLFFLITTTSTTTFLLFTSSVTCRPLISPSPENPPPSNFSPFKPTIAVVVAVITTLFSV
TFLLLMYIKHCKQQQQSLSSNSQQSAYYQYHTTRFPFSGRKNSGIDPVIIESLPVFRFKY
LRGEKNGLECAVCLNRFEPEEILRLLPKCKHAFHVECVDTWLDAHSTCPLCRFRVDPEDV
LLIDRVIDHADLGLGLGLPESTNRISGRHSSAGERGNNNKTNNYKNINQNKNNDETTSYR
RSLDGSIAAVERRKDGMLLTVDKERRIEHKIVIEVVENQKLRGSSGGGGVHERWSDVQPY
DLLYLRSEMLMNEGRRSSASKRVQGSNNGVKMQGINEGGGNGNGNGRNVINERSVSEITG
LSRYSSRNTGGGGNEERERERHNGAVARWMAWISQSRTAGRLGA
>Sgl38045 E3_adaptor/Cullin_RING/SCF/F-box 12.8 0.0
MDRCKSKKSKSIEAHQHDIISDLPKEVLYKVMERLPIRDAARMSLLSQKWQDIWTSIPHL
CFDRNFFLSLKERRHKTYGYTNIVSNILFHHEGPILRFSMDLPLNPSLDIAPWISYLIRN
GLKELILSDASRTNLKLNFRHFSCCGLETLKLAHCRLSGPPNFKCFPKLVIIELVNVVLS
CNTFKVLMGNCSVLQKLNLTNCSGLECTDVLIDAPQLQVLILDWNFQSLELKCCENLVSA
SIGISSSKVRNKTSIHGLLKAVANSTKLERLCLRGQICRVFLKQLSLHTAFVRLSYLEFQ
SLNLDSLNDFSSLISCLQSFSNIQTLKINVITSTKLDEHVLDFNLHSTILYQLRFATIEF
SCCFNPELKLIEFLLVCSPVLEKLLVLPTKKVTQSFMSKILLQLNRFRRASPKVEVIVLE
PKISIDNVSSSSSSEDSSSS
>Sgl38056 E3_activity/RING/RING 10.8 13.6
MGDHLALLVNRLLTESTIHAAIESRNRAKELEEGIDVEFLKQKEDNGDGDLSSPRKLVEC
RICQDEDFDSNLETPCSCCGSLKYAHRRCVQRWCNEKGDTMCEICHQPFKPGYSAPPPLF
QYGHIRMNFRGNWQISRRELTQSQLMMEPVSTNHALLNSDLEEPSSRSFICRLTVAVIFI
GLLILRHTLPIMVGGSNELVLPLFILAVLRVAGILLLVYVTIMAISGLRRQRNQDETTNV
PETSSEEEEEENEHLESQQPSHVIQIS
>Sgl38081 E3_activity/RING/RING 35.1 7.3
MYSSIPQEIITSRHLHYSRRLLLETHSHSPPLPTPMIEAPTPTYQVLDPNSSHHKAGFDA
NIIMILAVLVSALICSLCINTLIRCVIKCSSILRGEPNYYLNMISDHDNDKKTKIGGVDK
RALKTFPVVKFLKDVKIQGLGTDCVICLSEFKVDEKIRILPKCNHGFHVKCIDQWLSSHS
SCPTCRQSLLETCQKIIGCGEDHVTSLSSSSSSSSTTTTISFSSTEEMITVSIDPLQRED
LIRNYRGD
>Sgl38118 E3_activity/RING/RING 29.6 13.3
MATPLTGIGHREGGGVAIMVNAVDPSPPSSSSSSSKASLKNSAQKSPILIFLFFHKAIKA
ELEGLHRAAIDFATNHGSDIKPLLERYHFLRSIYKHHCNAEDEVIFPALDIRVKNVARTY
SLEHEGESVLFDELFELLNRKVRDEEAYRRELASRTGALQTSISQHMSKEEEQVFPLLIE
KFSFEEQASLVWRFLCSIPVNMMVEFLPWLSSSVSIEESQDMRKCLRKIIPNEVLLHEVI
FTWMDGPKMDKFRTSCGATLQCCIDSKACASVGQIKGASCACESSHTGKRKRVKLSNSTA
DSDLSYPIDEIILWHKAINRELIEIAESARKMQLNDEFSDLSAFNERLHFITEVCIFHSI
AEDKVIFPAIDAELSFAQEHAEEESEFEKIRCLIENIKLANAESSLGELYSRLCSYADQI
LDTIQKHFHNEEIQVLPLARKLFTLQRQRELLYQSLCVMPLKLIERVLPWLVGSLGEEEA
KCFLKNMHMAAPDADVALVTLFSGWACKGSKMNVCLSSSAIGCCPARLPNGEGNEHLVSK
CTPCLANGDKAAIGHHDEESQLSKRCKIASTEKVSNLEEKRGDDSQKLSCGTLSCCVPGL
GVNNGNLVVSSLTAAKSLRSLSLSPTAPSLNSSLFNWETEISISDTGSTTRPIDNIFKFH
KAIRKDLEYLDAESGKLSECDEAFLRQFSGRFRLLWGLYKAHSNAEDDIVFPALESKEAL
HNVSHSYTLDHKQEEMLFEDISSALSELSQLRGAVSRSSAAVAPPGNDSDAGDSSAHLRK
YQELATKLQGMCKSIRVTLDQHVFREELELWPLFDKHFSVEDQDKIVGRIIGTTGAEVLQ
SMLPWVTSALTQEEQNKMMDTWKNATKNTMFSEWLNEWWERAAPSQPCSASEISLTQGHD
VCDALDSSDQTFKPGWKDIFRMNQNELESEIRKVSRDSSLDPRRKAYLIQNLMTSRWIAA
QQKSPHGGTGESSNGDDLLVLSYRDPEKKIFGCEHYKRNCKLRAACCGKFFTCRFCHDKV
SDHSMDRKATTEMMCMQCCKVQPVGAVCSTPSCNGLSMAQYYCNICKFFDDERSVYHCPF
CNLCRVGKGLGSDFFHCMTCNCCLSVKLVDHKCCEKGLETNCPICCDFLFTSSASVRALP
CGHFMHSACFQAYTCSNYICPICSKSLGDMAVYFGMLDALLASEQLPEEYRDRCQDILCN
DCGRKGTASRFRGVRFVANLGSHEGNLKPKRKRKVGGKE
>Sgl38198 E3_activity/RING/RING 17.9 4.5
MECLHRFCRECIDKSMRMGNNECPACRTHCASRRSLRDDQRFDQLIAVLYPDIRKFEEEV
MYELEDVDLQKICYEVPPKRKKKYFVLNDYFFAQIQESITQVLIKQSEALGKKRSSNKDA
AGPSVTRSQR
>Sgl38201 E3_adaptor/Cullin_RING/SCF/F-box 20.1 0.0
MEAFPPELIIEILLRLPVESLLRFKTVCKSWNSTIKTPSFIKSHLHQTLISNSHRRLLKL
SKMDDSKKRKFSFYSAEIDPESPTYSMLNHPLEFDKRATVFGSCNGVVSICDRSRPNYVL
LYNPFTNSRRILSAKGLPSYNKSEFGFWSLLVMAFLSMRLCITL
>Sgl38353 E3_activity/RING/RING 35.2 7.9
MSTSTVHPLMYQVQYARRLLLVQHSPVEQSPAVGGTAPTIAKNPIDPTEPYNGTNNGFDA
NVVMVLSVLLCALICSLGVNSIIKCALRCSNLMPASSNPPVGAEKGIKKKALKSFSVVNY
SPKLKLPGVGTECVICLSEFGEGERLRLLPKCHHGFHIRCIDKWLKTHSSCPTCRHCLIE
TCHKIIIVGCGQASSSSSSSSSTSLQTPLPTQTTVLNIAPLEREDFVSNY
>Sgl38383 E3_adaptor/Cullin_RING/DCX/DWD 136.4 28.8
MKCEVERAFIGAGCNRIVNNVSWGASNFTAFGAFNAVAIFCPQKAQILTTLPGHKTAVNC
TYWLPTSKFAFRAQQSKHHYLLSGDADGIIMLWELSLTDEKWRHVLTVPQPHKKGVTCIS
GIMFSATEAIFASTSSDGTVNIWEIILPVIAGGECKLSCLDSLAVGSKTMVALAIAELPD
NTGHVVLAMGGLDNKIHLYCGERTGKFVRACELKGHSDWIRSLDFSLPIRQNEARDGLLL
VSSSQDKSIRIWKLVLCETSGNSERKDIIGLASYIEGPIFICGSSTYQISLESLLIGHED
WVYSVQWQPPSVASEGGGYIQPQSILSASMDKTMMIWKPERTSGIWMNVVTVGELSHCAL
GFYGGHWGPNGDSILAHGYGGSFHLWKNVGVHSENWKPQKVPSGHFASVSDIAWAKSGKF
LLSVSHDQTTRIFAPWLSHMGDRCSWHEIARPQVHGHDFNCVTLIQGKGNHHFVSGADEK
VARVFEAPLSFLKSLNCAVAQDSDIQEDIQLDVQILGANMSALGLSQKPIYAHAAQDTAE
RPGPGSEAVDTLETVPEAVPVTLTEAPIEEQLAWHTLWPETHKLYGHGNELFSLCCDHEG
KLVASSCKAQTVSVAEIWLWQVGSWKAVGRLQSHSLTVTQMEFSYDDSLLLSVSRDRHFS
VFSIKRKDVDEISYELVVRQEAHKRIIWACSWNPFGHQFATGSRDKTVKLWTVVNKSSVK
LLLTLPTFQCSVTALSWLGTNRQTNQGLLAVGLENGLIELWGLSATRTEDECMTTSGFLA
NVVAKFDPFMCHASTVQRLAWRNSEKEEDCQYSQLASCGADNCVRVFDVDVKEF
>Sgl38390 E3_activity/RING/RING 35.2 7.9
MSTSRVQPLMYQVQYARRLLLVQHNPVEQSPAVGGTAPTIAKNPIDPTEPYNGTNNGFDA
NVVMVLSVLLCALICSLGVNSIIKCALRCSNLMPASSNPPVGAEKGIKKKALKSFSVVNY
SPKLKLPGVGTECVICLSEFGEGERLRLLPKCHHGFHIRCIDKWLKTHSSCPTCRHCLIE
TCHKIIIVGCGQASSSSSLQTPLPTQTTVLNIAPLEREDFVSNY
>Sgl38443 E3_adaptor/Cullin_RING/SCF/F-box 13.6 0.1
MEEVEAIEILEQQHLPHDLVAQHILTRLPIKSLLKFKCVAKQWYSTISSYHFAHTHFKLC
PFNHPNSPTQFLFVQNRSNYYLFAYDNGNEIGATVDKNLVNLRINFHDDELVLVGSCNGL
VCLASYCGFYFILWNPITGQFCKYLDHELLVDFSSKFRVSWGFGYVSCVDDYRIVRILES
NTTVEIRVHVFSLRTKKWSRIDDEVYQDIFSLRTKNHVSIGTDSFRVPVSFYSRQGVLVN
ETLYWIVSKTNDWGRKVVSFDLVHEIFDTVSDLSLVSNDAFKDKFLCVMGGCLSKFGVSI
HDDVYIGILKGPGKVESIRLSKYLRLRSCQSFVGFTRSGGFFILLEDSTIGVVNPTSQPM
KYKYTPLVTFESLGKTRVANYAPSLISPYPVA
>Sgl38482 E3_activity/RING/RING 32.7 7.6
MAFIQIPCCHNFFPVGKRVDVRIKYRVFERCTFVDHDENEFVTQFYPYNQGSKTILAINP
YCPYCKVELTTLFELMSYSAVESSTVLGFIQAKVERLLSLSQLELDHNNNDDLGDYSISL
DFYRRFERTFDEVTVRAWLERHSSVDAIEEEPGDCTPASEEAIQSLERITLTTSRKEDGS
AATCAICLDEQLMMRKNNDEIGRRMPCKHEFHEDCILKWLHTSHYCPLCRFELPTALSSS
KEVDSHELVIRDSDDVFTIDCSEQ
>Sgl38575 E3_adaptor/Cullin_RING/SCF/F-box 13 2.4
MGKVSPKEKESKTPKLKRRTRTSNNKYLRPGALAQLRYSKASSTKSCTDLGKKRVVLLDS
KKAVTNDLVNEPQATPVQETPMVSPQKFGFSSVLSPLEFVRQQSLPKTPKTPRPEDSVFD
SRLEALPIDLLVKVLCHLHHDQLKAVFHVSQRVRAGVIIARQYHFNYTTPDRSRQEMLKT
MTPLATEQWPFVSKGESKGFWLPSPHTPKAPRHGPRPPSRLKYTEMRQVAAALFQEASLP
SRCRIPSVLSKPPCKNRVLLYEDELCQAVAQNKLR
>Sgl38579 UBD/UBC-like/UBD_UBC 233.5 0.1
MAMKRILKELQDIRRDPPTSCSAGPVSENLYQWQATLIGPADSPYAGGVFVLSIHFPSDY
PFKPPKVAFRTKVFHPNINNNGNICLDILRDQWSPALTISKVLLSICSLLTDPNPDDPLV
PEIAHMYKKDRAKYEATAQSWTLNMNENSPNSICIYKRESLYNIYQSFTTKSETLCLMSY
GAAEIVQ
>Sgl38599 UBD/Alpha-Helix/UIM 28.5 12.1
MVLEATMICIDNSEWMRNGDYSPSRFQALSDAVNLICGAKTQSNPENTVGILTMAGKGVR
VLVTPTSDLGKILACMHGLDIGGEMNLAAGIQVAQLALKHRQNKKQQQRIIVFAGSPVKY
EKKVLEMIGKKLKKNSVALDVVDFGEDEEGKSEKLEALVSAVNNNETSHIVHVPPGANAL
SDVLISTPIFTGGDGEGGSGFAAAAAAAAAGGVSGFDFGVDPNLDPELALALRVSMEEER
ARQEAAAKRAAEEGGPSGEKGEEQSSQDVAMGESSNAANSEADKKTDLTEDDENALLQQA
LAMSMDDPASTTTVRDTDMADAAGDDQDLQLALQLSVEENAKESTSQSGQADMSNLLADQ
SFVSSILASLPGVDPNDPSVKDLLASMHNQSEKKDEDKPPSEEEKK
>Sgl38620 E3_adaptor/Cullin_RING/DCX/DWD 61.7 10.7
MAEDKVSLELTEETLQSMEVGMAFRDYSGRISSMDFHRNSSYLVTASDDESIRLYDVANA
TCLKTINSKKYGVDLVCFTSHPTTVIYSSKNGWDESLRLLSLNDNKYLRYFKGHHDRVVS
LSLCARNELFISGSLDRTVLLWDQRAEKCQGLLRVQGRPATVYDDQGLVFAIAFGGYIRM
FDARKYEKGPFDIYPVGGDFSDANVVKFSSDGRLLLLTTTNGFIHVLDSFRGTLLCSFNV
KPVSTTSTLEASFSPEGMFVISGSGDGSVYAWSVRSGKEVASWISTEKEPPVIKWAPGNI
MFATGSSELSFWVPDLSKLGTYAARKLT
>Sgl38657 UBD/Alpha-Helix/UIM 28.5 12.1
MVLEATMICIDNSEWMRNGDYSPSRFQALSDAVNLICGAKTQSNPENTVGILTMAGKGVR
VLVTPTSDLGKILACMHGLDIGGEMNLAAGIQVAQLALKHRQNKKQQQRIIVFAGSPVKY
EKKVLEMIGKKLKKNSVALDVVDFGEDEEGKSEKLEALVSAVNNNETSHIVHVPPGANAL
SDVLISTPIFTGGDGEGGSGFAAAAAAAAAGGVSGFDFGVDPNLDPELALALRVSMEEER
ARQEAAAKRAAEEGGPSGEKGEEQSSQDVAMGESSNAANSEADKKTDLTEDDENALLQQA
LAMSMDDPASTTTVRDTDMADAAGDDQDLQLALQLSVEENAKESTSQSGQADMSNLLADQ
SFVSSILASLPGVDPNDPSVKDLLASMHNQSEKKDEDKPPSEEEKK
>Sgl38676 UBD/UBC-like/UBD_UBC 233.3 0.1
MAMKRILKELQDIRRDPPTSCSAGPVSENLYQWQATLIGPADSPYAGGVFVLSIHFPSDY
PFKPPKVAFRTKVFHPNINNNGNICLDILRDQWSPALTISKVLLSICSLLTDPNPDDPLV
PEIAHMYKKDRVKYEATAQSWTLKYAMN
>Sgl38682 E3_adaptor/Cullin_RING/SCF/F-box 13 2.4
MGKVSPKEKESKTPKLKRRTRTSNNKYLRPGALAQLRYSKASSTKSCTDLGKKRVVLLDS
KKAVTNDLVNEQQPTPVQETPMVSPQKFGFSSVLSPLEFVRQQSLPKTPKTPRPEDSVFD
SRLEALPIDLLVKVLCHLHHDQLKAVFHVSQRVRAGVIIARQYHFNYTTPDRSRQEMLKT
MTPLATEQWPFVSKGESKGFWLPSPHTPKAPRHGPRPPSRLKYTEMRQVAAALFQEASLP
SRCRIPSVLSKPPCKNRVLLYEDELCQAVAQNKLR
>Sgl38733 UBD/Alpha-Helix/UIM 15.5 1.1
MEDVLSPTDQQSMVSSFLEIAVGQTAETARQFLQATSWKLEEAIQLFYVGNESGAIASSS
FLPTEEIANPTPVANKSFSGSDEALARELSGLNGGDDDVRAPLPVIREALYDDALLYGGS
RIGYPSHVPGSVVAFRNFEEEMKHPAVWESEQGGSSSTESSRDNLAALYRPPFDLMHQGP
FEKAKLAASAEDKWLLANLQSPTEFSSHMLNRDTWANEAVAQTIKTNFIFWQVYDDTSEG
KKVCTYYKIESVPVVLVIDPVTGQKMRAWSGMVHPDRLLEDLMPFLDGGPRNHHSSLSHK
RPRESSNAPVPKSPVETNEEDEELQQALAASMENMTHPNQESAEDKGAGIVSKEEETCST
KKPVYLPLPEEPKGDRSLLCRVGFRLPDGRRIQRNFLRTDPVQLLWSFCSAQLGEAETRP
FRLTHAIPGATKTLDYESNLTFEESGLSNSMISITWE
>Sgl38789 E3_activity/RING/RING 27.7 5.7
MRCLGCCWCLLVETCAICLGTLNVGGGQALFTAECSHSFHFSCIASNVQHGNHLCPTCRA
TWDLVAVLDISESMDGDKIRLLKQAVGFVADNLGRSDTIRAVNKLRAKGTTNIVGGLKLG
VEFLHSLCDLPPCIRSNYVHLATNVLRTDVVPVYTFGFGVDHDATALHAIADGSGGTFSY
IESIEIIQDAFARCIGGLLSVVSQELEIHLNSASQGSKFSPYPLVVPPADTETLKMQLLE
VKCSYKDPLSNQNLMSENVSVEIRRPINRDLTEEDKQVCLELDRERNRVLIAEGIEEAQA
MAERGELSRARATLEQWSRNLGNQLQHRQGMLCVDGWNVRWMRYTGE
>Sgl38790 E3_activity/RING/RING 22.9 0.7
MSRMVRKSQELLFPRKKDEKSAASSSTALNATQGQALFTAECSHIFHFTCVASNVQHGNY
ICPTCRPLGHNHSNSFPVLISIQAPALPPEASDRPSDRAPIDLIAVLDVSGSMNGDKIRL
LKQAVRFVVDNLGPTDRLSIITFSTTAWRVTPLRRMTEAGKSGTIRAVNNLHGQDNQNGY
GSSFLHSLRDLPPCIRANDVHLPTNTPPTDAVPVYTFGFGADHDATALHAIADGSGGTFS
YIESIEIIQDAFARCIGGLLSVVSQELEIHLSSVSQVVQIGSISSGRYRNNIDSGGLHGI
IYVGEVYAEEEKKFLAYLSVPPADTETSHTQLLEDLSEEDRKVSLVVDREINRVSIAEWI
TKAQVMAERGDLSSARAMLQQRRMELMQSASAQAGDPLCGQLVSEMSDIQQRMSSRSEYE
RGGRAYTYSRTSAHMSQRASTQAVRSHQMPTPIDRKSALVGGAVRAPLLVVPLLRVIRWT
IRPHMRRMVQKSQLSIKPENQK
>Sgl38791 E3_activity/RING/RING 26.5 5.0
MDSKETCAICLAALNATQGLALFTAECSHVFHFTCIASNVQHGNYICPTCRATWANLPSQ
FIPTSPTYVPNHHNPAYTSLSFADDEPLPIPSPVPPTSAPQNDSSMTIKALPEYPALSKS
YQSNSFPVLIAIQAPPLSPEASDRPTTDRAPLDLVAVLDVSGSMNGDKIRLLKQAVGFVA
DNLGPTDRLSVIPFSNSAWRVTSLLRMTDAGKSDTIRAVNNLRANGSTNIIGGLKLAVEV
LMQRREKNPVSSIIVLSDGQDNQNWHGSNFLHSLRDLPPCIRSNDVNLATNVPLADVVPV
YTFGFGADHDATALHAIADGSGGTFSYIESIEIIQDAFARCIGGLLSVISQELEIHLSSV
YQGVQIGSISSGRYRNNIDSGGLHGIIYVGEVYAEEEKKFLAYLSVPPADTETLNTQLLE
VKCSYKDPLSNQTITSEIVTVDISRPLAEDLSEEDNQVCLEVDRERNRVSIAEGITQAQA
MAERGDLSSAQAMLRQRRLELMQTASSQAGDPYCGQLVNEMSEIHGLMSSRSEYEGGGRA
YAYSRTTRIARHSAPPGDRMDYQTSSMKRMVEKSQLSFGPENQDGNSSASSSNNSINPWD
VT
>Sgl38793 E3_activity/RING/RING 41.4 3.8
MDVQSITLDEEQELLSYLSNDNGVEVTSFAFEKASASASASASVTKPVDDFFSVWLRYQD
SRRYPNERNAWFEFRKDNQDILGLVLNLFDDGLEFTVDANAYDCVIDVVQESCDVLLQQV
SEVGRKSLAMTVMIKVDAAEDVDDVAAVDDEVNNNDMDYSSYEDVESDDEEVMAIMSSTE
VKDYLSSNGGVRFLRSDQANTNTVVECCSICLEEFDKRGDDVAVLPCSHVLHTDCLVPWI
SKGKDTCPMCRFNLLN
>Sgl38812 ULD/UDP/UBQ/UBQ_Other 43.1 0.0
MPEEDLVEVKFRLYDGSDIGPFWYAPSSTVGHLKEKIVTEWPKDKKLTPKAVNDVKIINA
GKILENSKTVGQCQMPFGELQSGAITMHVVVQPTVAKTKAEKKVDEAEKKSVCSCSIL
>Sgl38840 UBD/Alpha-Helix/UBA 22.8 1.7
MEDEEMQKLLNMGFSKELASQALAATGGQSTLKATEWLLSHPHTLSKPSIPHFQSQSQSQ
SQSQSKLNKFFPFNSSKDSKQPSSQIPETPQIPHPNKRPKPGPKPVPHEPLSERMRPRVV
DEVVGQDHIVGPNSFLSSAIKCNRLPSIVLWGPPGTGKTSIAKAIVNSCSSSYKLVSLSA
VYSGVKDVREAVEGARKLNEFGGGKRSVLFVDEVHRFNKSQQDSFLPVIEDGSIVFIGAT
TENPSFHLVTPLLSRCRVLTLSPLCPLGIEKLLRRAVDDSEKGVSLSVGRKAEVEHEVIE
MLSSQCDGDARVALNALEVCATTALGRVQGKGQSSEGSESCLNDGVLVINVEDVKEVLQC
KHVAYDRAGEEHYNLISALIKSMRGSDANAAIYWLARMLEGGEQPLCIARRLVVFASEDV
GLADPNALLQAVACHQACHFVGMPECRLNLSQCVAYLALAPKSVAVYKALNEAMKVVKDS
VGGNPGVPLHLRNAPTKLMGELGYGKGYIYTPDNPTAEQSFLPPSLQGRKFLEWPPSDT
>Sgl38864 E3_adaptor/Cullin_RING/DCX/DWD 87.6 16.8
MGGVEDGQPPSKRLRLSCAGSSSVSSGVRAEEPVAAGSLRDLMARPRQCQGEEEVIGSRG
IIKKLEFVRLIAGALYALGYERSGASLEEESGVPLHSSAIKLLMQHVLDGDWDECATILQ
DICLEDETLMKLAKFLILEQKFFELLDSGKTMDALTTLRTEISPLQIKTNRVHELSICIL
HHPLMSQNGTAHKDSVKPRSRTEVLFELQKLLPPKIMVPARRLEYLVEQALNLQRETCLF
HNSSDFDMSLYADHHCGRDNIPRYTLQVLQDHKDEVWFLQFSHDGKYLASASNDRSTIIW
EVSVDGEVVFKHRLCGHQKPVSQIAWSPDDQQILTCGTEETVRRWDVLSGECLQVYEKAG
YLAISCAWSPDGESVFAGFSDKSLCMWDLNGKELECWKGQKTVKISDLAVTLDGKQIISI
CRETAILLLDRETKVEKLIEEDQAITSFSLSNDGKFLLVNLINEEIHLWTIDGDIKLVAK
YNGHKRSRFLVRSCFGGLEQSFIASGSEDSQVYIWGRSSGQLVDILPGHSGVVNCVSWNP
VDPHMLATASDDRTIRIWGLGGANMRRRVCQSNGTHHSNSNGTHHSL
>Sgl38889 E3_adaptor/Cullin_RING/SCF/F-box 19.1 0.1
MNSLCYVYLPENIIFEILLRLPTKTLIQCKAVCKQWKSIITTSFFARSQLRFLKQQFILP
PYYLLCSYDWSFALNLIHNSRHYRQCITSKELENQVLPLSSKSFELTFDKDILLSTCNGI
MCFYLKEKISLCLWNPTIDETRFVALPYESYWIRKFYFVGFGYASSIDDYKIVLAAKYAC
HTSNTINDRRSLGVYSLRRNEWRELDFDYYKSIAPEIYSGLGWRSGRQPSSNGIRMESIV
VNDALHWVIDSYICNKNMKFFLYKFDLVNEYFEKVDVDLNKIISNIIVDDDNRLGPRQIE
IGVTENRLVIYQLYSEFRHSNPSNEFLVKRDVVKAWEMAEQYDYNSWKIKFRYVGDWDDI
RDNHDLVRITGNGNVLIIGGTYAEYESRLSFDQNSHKQRAQDVDFYAKHYVPSLVSPNNF
>Sgl38947 E3_adaptor/Cullin_RING/SCF/SKP1 112.5 1.0
MASNKKITLKSSDGETFEVDEVVALESQTIKHMVEDDCADNVIPLPNVTSKILSKVIEYC
KKHVDSPKSSENNDRQVDEELKNWDADFVKVDQATLFDLILAANYLNIKSLLDLTCQTVA
DMIKGKTPEEIRKTFNIKNDFTPEEEEEVRRENQWAFE
>Sgl38950 E3_activity/RING/RING 31.5 13.7
MFKRSRTSQRKKNFICLCFNFMGIRRNVKEVQRLSFTSDDDVCCVCLSSLSKEGEDIKVL
PCCHHFHSKCVDKWFKARRKTCPICRFIVEEERKEEELSREMVIWYSSFHVTGLSGIY
>Sgl38992 E3_activity/RING/U-box 79.1 0.2
MDDTTMDTMMQQQQLHLHEKVHVVLSKEMQQEDGLSTLNWILNHWSSQSSHQLLSIVILF
ITSSSSSSSSSSSSSLDLVDTPFGKLPATSVNDNMLQIISNCEQQKTDKLLSNYIAFCGK
VRTEVHKINNTNDQPIQKTLVDLIIQKRITKLVMGMTFMRSSSGRTKSAISESVYIHRTK
PDFCELFILFKGKLVMVKEENDGGCIEDEEGVVVAKLKQKTSFKGWFGKMLSHGHGQVKS
SSTCPSTQCSSSADSDSLVSRNRNQWQFYEQDIEEYYQELMMSESKSIEDKDNNIDEIQP
YSMNDPNEQNILADSIQGPGDRVEDLKNKIQAARKMIESNKNVAKAEVDRQAKASWAICL
CNHRAEQLQAHTEEEIKIRNDLTKEIEETKEDIQETLPAVEDSNKRLNSLFERQSELSSR
LHFSSLAKLGVEGQLEKAAKTRAELVKEIEELRKQRDVFQRRIDFCKEKDAIGLATRMSE
PVSCSYREFSANEIRLATDNFATYRRLASGRDGSSVYKGRISCMSVAVKMLDSYVGMTQE
TFQAKVNLLAYIRHPNIIAFIGFCSELKCFVFEYMHNGCLRDILFSRIKARTLKWHQRIQ
IATQVTLALRFLHLAEPRPIVSGYLNPSAIFLDRNVVAKLQSFNLTPCSNESDIQAEVVS
FGDLLLQLLTGRNWTGVHEAKTIDKHAIFEALDKNAGDWPLDLVEEIVELATKCRSINSE
TSVGAFMSSVTEELNRLKKKADEVITRKEDHILSEDHTSSGHEWSHAPTSFLCPILQVVM
ENPHIAADGYSYELEAIEEWLRMGHDTSPVTNQKLKHKQVIPNKNLRFLIQDWRKLTSLL
ENANSSNDDDSGHLNIQSTDWCPNVFV
>Sgl39020 DUB/USP 187.7 0.4
MVRWNQMKLNREIRVSSLLNKFKSGYKMLSNIQWVSAYGSHLSAATILGVVGLLLAVRDG
RIVNITSFSTTNCSSEKLYFVPGLKNLGNNCFLNVVLQSLASCLRFRSFLENVLELQASL
PVVQVDASPLLISLSDLLEELSTLQEKSRPLNPQKVMAAMQQYIPQFQLSNQQDAAEAFL
HLLSCLRDELSDSYMPNYGSLTDVAAPTSRILAFERINNSKEPERWQKQYLGPFNGILGS
FLTCQTCSSEIMMDFGFFHTLPLSPIPYSGASIMHNFTLEDCMKRFLAPEHIENYSCSRC
WHIAATKFLSTFGGQQEDIRKLSCCSEQDLCNCRKISSLHTLPWTNHFSRAFKQLSIAHC
PQILCFHLQRSSMNAFGEFVKIQGHIFFPPILDLSPFAKYEVGIENLKTKNSKSVAEKPC
VASTTYQRSVDRDSNPMTNLTIETFQYFPDPCSSLSGIYSNSEVMHTLEITDGPAVPKSI
LYRLVSVVEHFGRAGSGHYTVYRGVTTETEDAGETKTHLQWFRISDSEVHNASEEDVLGA
EATLLFYERI
>Sgl39023 E3_adaptor/Cullin_RING/DCX/DWD 108.5 22.8
MSGGVEELPKKETSVLRGHEGAVLGARFNSDGNYCLSCGKDRTIRLWNPHRGIHIKTYKS
HGREVRDIDVTLDNSKLVSCGGDRQVFYWDVSTARVIRKFHGHDSEVNAVKFNHSSSVAV
SAGYDRSVRAWDCRSHSTEPIQIIDSFQDSVMSLCLTNTQIIAASVDGTVRTFDIRIARE
LSDNLGQPVNCISLSNDANCVLASCLDSTLRLLDRSSGELLQQYKGHVCKSYKSDCCLTN
TDAHVTAGSEDGFIYFWDLVDATVASSFRAHASVVTSVSYHPKDNCMISASVDGTIRVWK
T
>Sgl39040 E3_activity/RING/U-box 106.3 0.2
MGKQDLYISIPSFFRCPISLDIMKSPVSLSTGVTYDRTSIQRWLENGNNTCPATMQVLDS
KDFVPNHTLQRLIQIWYNNNNHNHNHLSQSSKSKPPQFHSLSANQIADLIKQLLGGQIIK
KRVLFETFVKILCFATESAENRRFLLSNQPFLYHLVFTVSAEVAPGSDPDLLEAVLKTLH
LVIASRDVNLSHLRQKMGNSCDFLQTLLRILRTGCSGSRVAAIGIIEELRRHSESKKAVF
DHQELVPELLELVKCGKLEKDGEIQPVLSCLISLSSTRRNKLKLVRAEGVKLVGDILSSY
QTPNNNNNYDNNNNNNNNNNNNNNNNNNSKNVIIMIELLLTLLEMLAGCTEGRSAISEDP
NCVPMIINKLMKVSKAANEHGIALLWSMCYLFRDQKARDSVVNSNTGLTKILLLMQTDSS
PAVKQMCCDLLRIFKVNSKSCLSSYETKTTHIMPC
>Sgl39041 E3_adaptor/Cullin_RING/DCX/DWD 97.3 7.7
MVRCVSVEEDMFFDSVDHLLSTEDDDSSYVEMGVLSYEFWKDEPRSIKERRQNFLQEMGF
DAPCCSSSLEFNAVDDDVGLEVGMERMVLGSNEAVSSSSSCSTTDDCEQVEFCARECNGN
SAEKEDVSQSEWKVSNSNKCKCINKKIRHWWNEMMNKQRERVSGCKCKLYNEECKKCERS
RTKVQVNKKKIKEISALFEAQEIRAHEGIIWTMKFSPNGQYLATGGEDGVVRVWRVKPVD
SSLEKLKTSFRREKKVMIPVVVPDKMFRIEQVPVQELHGHVADVLDLAWSDSNFLLSSSM
DKTVRLWQLGSDVCLNTFHHTDYVTCVQFNPTDNRYFISGSIDGKVRKWGVSEQRVLDWA
EIRDAVTAVCYQPNGQAFVVGSLNGSCRFYETKGELFEQSAHVQLHSSKRSATNRIAGIQ
FSPEDPQKVMVMSEDSKLRILDKMDVVSKFRGLTKSGSQTSASFTSNGRHIISIGHDSNV
YVWSHEETVQLLPKQTKSTRSCEYFYSDGVTVAVPWCGTETAAPKVDSSGNTEHDPACIS
RDPPSFSLSNMLASKSSATWPEDMFPIFNQPEQQCQTRNNVIARCNPVWGLVIVTANRDG
MIRTFHNYGLPIKA
>Sgl39054 E3_adaptor/Cullin_RING/DCX/DWD 74 5.8
MKGGTVQINWHDTKPVLTLDFHPISGLLATGGADFDIKIWKVDSVEEQKKTPSASYQTSL
CYHSSAVNVLRFSPSGEFLASGADGGELILWKSHITDAGQVWKVFKTLSFHRKDVLDLQW
SRNGTYIISGSVDNSCIIWDAEKGSVHQILDAHLHYVQGVAWDPLSKYVASISSDRTCRI
YVNKPQKAKGVEKMNYACQNVIVKAEQQSADDAKSVKNNLFHDETLPSFFRRLAWSPDGS
FLIVPAGLYKCSPESESINTAYIFSRKDFSRPALQLPSASKPVVAVHFCPLTFNLRGSTS
AGFFKLPYRLIFAVATLNSLYIYDTESVAPLAILAGLHYAAITDIAWSPDGNFLAVSSQD
GFCTLVEFQSDELGSPIPFPDGKTEICPVGVTLNQQKPKEVLVKTSVKDRPVVIENNKTD
NKQAVPVATNASSKPAICPVGVTPNQQKLEEVLVKTSVEDSPVIKNNQTVHKQAVPVAKS
TPVSSKPAKRRITPMAIDP
>Sgl39061 E3_activity/RING/U-box 106.2 0.2
MGKQDLYISIPSFFRCPISLDIMKSPVSLSTGVTYDRTSIQRWLENGNNTCPATMQVLDS
KDFVPNHTLQRLIQIWYNNHNHLSQSSKSKPPQFHSLSANQIADLIKQLLGGQIIKKRVL
FESFVKILCFATESAENRRFLASNQPFLDHLVFTVSAEVGPSSDPDLLEAVLKTLHLVIA
SRDVNLSHVRQKMGNSCDFLQTLVRILRTGRPGSKVAAIGIIEELRRHSESKKAVFDHQE
LVPELLELVKCGKLEKDGEIQAVLSCLISLSCTRRNKLKLVRAEGVKLVGDILSSYQTPN
NNSDNSSNNSNSKNVIIMIELLLTLLEMLAGCTEGRSAISEDPNCVPMIINKLMKVSKAA
NEHGIALLWSMCYLFRDQKARDSVVNSNSGLTKILLLMQSDCSPAVKQMCCDLLRIFKVN
SKSCLSSYETKTTHIMPC
>Sgl39076 E3_adaptor/Cullin_RING/DCX/DWD 33.4 0.9
MLFLVADLPGFYFDPEKNRYFPIEGPIPGSSRKQTTPLQNSDSLITKVSKNPKKDVSISK
LVHLKELCGNFVGSSYGKVSFQEECKKQLVSNPKVWKYQNTHQGADCSLALLHITVETPQ
GQCATDALIAGDISGSVNLFDVGGIGQYFSHGMMSTAVSVWPERDEPNSHQSLKNIWLFD
EAALMMPSSVSSICAFRKVGTDNDSFAPQQALITTLGSEYASGGLYIVNLADPVELDSLY
FSDAAMRRFSQHISLNCTVWEANIGPCGRQAVVGTSLGAKMVDLESGVSSMICSSKSDVL
SVQLIQSGNVALCGLRNGTIVTVDARQRQRQLARHRIPCSSNKSSTLAQKKTTPFFVLRG
DIQPSCTVYMPSSICCLESLQLYDQYFLASSMDGSINLYDHRLTNRGPVQSYEGQVNSHS
RIKLAADASESFIMSGGEDCKVRVWNINSGKMLFEEKFMNSISMSVLWQGNTERICKGRS
SEEGWHAQTPGWNAWLGSGEGLFRMQFCS
>Sgl39078 E3_activity/RING/U-box 109.3 0.2
MMREIEIMSIPELFRCPISLDLLSDPVTLCTGQTYDRSSIEKWISAGNFTCPVTMQKLHD
LSLVPNHTLRHLIDQWLLKSNHHHRHYWKMGCSSSSSSTSDDIMFLKNVLESKDSSLEKR
MQVLEKVRILSQDLPWKNEGLIQMGFLPLILRLVFVKNNIITKEIIMGLVEKSLDCVLKL
IPFSCLSDLNMLIEESKFESFKLLLQQGSNVVKIGLCNIIEMVCLQSSLLATKLGNDTKI
LQCLISYVNIDCNDNNHDLEVSEAGIKAILSLITTPWYRENLVKEGLVGSLMTYIVEIVE
RKDKEVGSKATKALELVLEMEKGREEFMVNEVLAKEVIRALIKMVFIVSGDDEGSESAVN
CVMILCEESLEMSEEAICGGILTQLLLLLQSQCSGRAKTRARMLLKLLRSMWAKDQKHVL
>Sgl39199 DUB/USP 331.1 11.4
MGAAGSKLEKALGEQFPEGERYFGLENFGNTCYCNSVLQALYFCVPFREQLLEYYSNSKS
TVDAEENLLTCLADLFTQISSQKKKTGVIAPKRFVQRLKKQNELFRSYMHQDAHEFLNFL
LNELVDILEKETQATKGDQETLSSEKAANGPTNVQANHFQKEPLVTWVHKNFQGILTNET
RCLRCETVTAREETFFDLSLDIEQNSSITSCLKNFSSTETLNAEDKFFCDNCCSLQEAQK
RMKIKRPPHVLVIHLKRFKYMEHLGRYKKLAYRVVFPLELKLSDTVEDADREYSLFAVVV
HVGSGPNHGHYVSLVKSHNHWLFFDDENVEMIDESAVQTFFGSAQDYSSNTDHGYILFYE
SLGHSSSS
>Sgl39228 E3_adaptor/Cullin_RING/DCX/DWD 42.7 0.2
MEKLEFRYVDCCKRHKVLPNPAILSSLSKVEHQKSLQRLSSLVVVLDQLKDDDLLPIIDL
INAMCSSDVDVVDVLNESPCILHEDQVLSLMCAANQKLRTVSLQDLPFTKRFLRYLFQYG
LCCEELKLSSSSLQKLDMVGCFMQLRKLNLDFCTALTTLNKDCFSHMPNLMQLSLCETRV
TNLWTTSVALSKLPSLIELRFQNCLCCEDTGPCPSTNKLGFHVRNTDHPTGPTSTCSDHL
QNLSLLDLSTDHYCSKKAFHDEPDVYDGCDTDLSEALEVVSTRKKYISHHPSPLCFEKHY
REFLIATLPRLEVLDNIPIRKKDKKLAQVLYSTYFEYLPYRRHTENNVSRILHNREIASG
GTPFRTPLKLKQASSHRKSQHSFSRSLCAAKLGASPWPLLQSLSNTSCVTNEVSRRFRPR
QFEYHPSDASLMAFGTLDGEVVVINHENGKIFAYVPPLGARNSILGLCWLKKYPFKVLAG
SDNGMLRLYDISNTSAKGGYSCYGGDFTTADKFDQLTSVHINSTDELLLVSGYTRNVAMY
DMVAGKRLQLFSNLHEEPINVAKFSHLSPFMFATSSFDHDVKMWDIRQRTVRPCYTATSS
RGNVMVCFSPDDRYLLVSAVDNEVKQLLAVDGRLHTDFGIASSGSSHNYTRSYYMNGSDY
IISGSSDEHVVRICCSQTGRRLRDVYFEGKGSDKAMFVQSLRSDPFRPFNMSILGSYAQS
NSKCEIIKVNLLSSSEDTEENSYLQQSSCLSFSLGG
>Sgl39242 E3_adaptor/Cullin_RING/DCX/DWD 170.5 19.3
MTSISSVELNLLIFRYLQESGFTHSAFALGYEAAINKCPIDGSLVPPGALITFVQKGLQY
LEMEANLNNGDADIDEDFSFIQPMDLITKDVNELRRIVKEKRRSSRKDREKESEKDRDRE
RKRGRDNRRLDKDKDHVKDGEGKEKDEKAVREKNNKAVREREEKVAREREEKAVREREEK
VAREKEEKAVREREEKAARERDEKAARERDEKAARERDEKAAREREEKAGKEREVKAGKE
REEKAGKVKEEKAGKERDEKIVKEREEKAGRQWEEKAGKEKEEKAKLQDGAFDKESIVDR
EEKPVLKKEDDGVCPDPEPMDMSPSAPSVECEISASDVTILEGHTSEVCACAWSPSGSLL
ASGSGDSTARIWAMSERGSRSHIGSTNFVVLKHVKGYTKEKSKDVTTLDWNGEGTLLATG
SYDGHARIWNTNGDLKSTLTKHKGPIFSLKWNKKGDYLLTGSCDKTAIVWDVKAEEPKQE
FEFHSGPTLDVDWRNNVSFASSSTDNMIYVCKIGENSPVKTFAGHQGEVNCVKWDPTGTL
LASCSDDSTAKVWSMKQDGFVHDLKDHSKEIYTIRWSPTGSGTNNPNQQLVLASASFDST
VKLWDVELGKLLHSLNGHREAVYSVAFSPNGEYLASGSLDRSLHVWSLKEKKIVKTYSGN
GGIFEVCWNKEGDRIAACFANNTVCVLDFRM
>Sgl39257 E3_adaptor/Cullin_RING/SCF/F-box 19.6 0.1
MGQSTSTPAHSSELVRNHSRSFSLASRFTSSSSRKKTNNSMIPPSSPPHPQSPPSKPEPT
TGSYFSLLPDPTSNIPDECLAHIFQSLPSGDRKRCSLVCKRWLIVEGQSRCRLSLNANFE
IASHLPSIFSRFDSVTKLALRCDRRSVSISDDNLVLISLRCRNLTRLKLRGCRELSDLGI
AAFAQNCKSLKKLSCGSCVFGAKGLNAVFEHCVLLEEISIKRLRGINNDGDSEPVGEPIG
PGLAAKSMKSICLKELYNGQLFGPLIVGSKNLKTLKLIRCLGEWDRVLEMMATSNSNSTN
SEGNYDGLVEIHLERIQVTDFGLSAISSCSKLEILHLVKTPECTNLGIVSVAERCKLLRK
VHIDGWRTNKIGDEGLTALGKNCANLQELVLIGINPTTTSLDVIASNCRNLERLALCSSE
TIGDVEMSCIASKCLALKKFCIKSCPISDDGLEALAGGCPNLVKIKVKKCRDVTREVVEW
LRGKRESLIVNLDADEIEAVDASASEAGGPQEDATDFPVVDTEVTSVQAPGRSNGRGSLF
RTKFSFLFGRNIAACALRRWSTGSSNTNGNE
>Sgl39274 UBD/UBC-like/UBD_UBC 91.8 0.0
MSGGIARGRLAEERKQWRKNHPHGFVAKPDTQPDGSMNLLQWQCIIPGKSGTDWEGGYYP
LTMHFSEEYPSKPPKCKFPAGFFHPNVYPSGTVCLSILNEDCDWRPAITVKQILVGIQDL
LDSPNAADPAQTEGYHLFIQDTVEYKRRVRLQAKQYPATI
>Sgl39276 ULD/UDP/UFD/UBX 32.2 0.0
MGDMKDKFKGFMKKVNNQLAPSSSGKFQGQGRVLGSSSSSSGSQYVNPNRNFNPSSANSK
PFSNNNPNSNPPITRPTSLEGQKDSISNTNVISNSSSNSNPDLNRNQPSKDGFDPFGSLI
TTGKRNKNGYSLNVFECPICNSGFGSEEEVSLHVESCIAHTGSNDVGSGGGGDADVVDSN
LGSVEEVSADNEDKSTNKLETCVGVYLSGNPGEGSIDVVLRLLRNIVKEPENGKFRRIRM
GNPKIKEAIGEVAGGIELLEVVGFELKQEEAEMWAVMDSPSGERIALLKDSVQLLEQVKG
GISSACLVNVDEKVETEKKLKESEPKIIDRQIKVFFSVSENAAARIVLPDSFYNLSLDEV
RREAEMRKKKLAESQLLIPKSYKEKQAQAARRKYIRCIIRVQFPDGVVLQGVFSPREPTT
ALYEFVSSALKQQGLEFELVHPLPVKRRVIPCFPAAGQKASTLEEEDLVPSALVKFKPFE
TDSMVFTGLTNELLEISEPLVSSTS
>Sgl39289 E3_adaptor/Cullin_RING/SCF/F-box 19.9 0.0
MMMMKLSIMGEYEKEEESEIEKLPTDLLSHIFFLLTSFTDLAQASCVCKKWREGVKQSMG
RRESLSFSGCKMDDASTSRLVHLAFSLKELDISRSRWGCQITDIGLFEISMAKCVGKMTS
ISLWGMTGITDKGVVQLVSRATSLQHLNIGGTFITDESLVAIGNNCLHLKTIVLWSCRHV
TEIGLLYLVSKCRNLKSINVWGTRVPVNCFIGLLTISPALQIKPTGLLPNAEAIPV
>Sgl39307 E3_adaptor/Cullin_RING/SCF/F-box 19.9 0.0
MMMMKLSIMGEYEKEEESEIEKLPTDLLSHIFFLLTSFTDLAQASCVCKKWREGVKQSMG
RRESLSFSGCKMDDASTSRLVHLAFSLKELDISRSRWGCQITDIGLFEISMAKCVGKMTS
ISLWGMTGITDKGVVQLVSRATSLQHLNIGGTFITDESLVAIGNNCLHLKTIVLWSCRHV
TEIGLLYLVSKCRNLKSINVWGTRVPVNCFIGLLTISPALQIKPTGLLPNAEAIPV
>Sgl39405 E3_activity/RING/RING 17 0.4
MNYWKAGAMYRGSTPTPVAQIPFRFNYISKKLQAPNHMDNLISLPEKKIIEVLLECVERK
NLPEAYKGNLRVSCKCFASGSQHFVNKWIQVVPKPEISTYEPILIHVSLSITPPTPAPQV
FHMLPFVNEVKDQTLVIDTDGNNVLNLQMREFSTPGLSKEVIHITRNENGGRLFELSGHK
MAWCDVLFLGRKLDYEPKNDEKKRSEQDFMSAVEFSVEYPYGRAIGLLDYNHGILKQVEV
AEVGVVGGGLPCGHLFCNSVELGSPEMMIHPKTTKNKTDFGVVGIDASIVDVQQGISQNE
WCSEDGCSNEYGNAIIYGGRGGVYSCSGDGGGGGGGGGGGGGGGLPCGHLFCNSVELGSS
KIKPLMKTTPTS
>Sgl39440 E3_activity/RING/RING 31.4 8.7
MAFMQIPCCHNFFPIGKRVDVRIKYRVFERCTFVDDDENEFVTQFYPYNQGSETILGINP
YCPDCKVELTTLFELMSYSVVECSTVVGFIQAKVERLLSQSQLELDHDNNDDLGDYSISL
DFYRRFERTFDEVTVRAWLERHSSVDAIDEEPGDCTPASEEAIQSLERITLTTSRKEDGS
AATCAICLGLMMRKNNNEFGRRMPCKHEFHEDCILKWLHTSHYCPLCRFELPTSSSSSKE
VDSHELVIRDSDDVFTIDCSEQ
>Sgl39441 E3_activity/RING/RING 32.9 7.3
MDSIQVPCSHDYSTSGRIVDITITHQNFEEHVYHIEDGSDVRRLNPLNTQTTPMSINPKC
PQCRDSLIASFDSIISPERTCTAVLDIVQETIDNLVSNNSDHDHALATLIMICFIKRRHY
HDYDENSAMEWAERASFEEAFKAGFTPASPESIRALERITEISSDESTTCAICLEQLLKN
KEEVGRRLPCRHEFHESCIFKWLSISHYCPLCRFQLPTFSSITPL
>Sgl39483 E3_adaptor/Cullin_RING/DCX/DWD 111.6 14.4
MFARSNSAQQQAQLYSDNNFENHQCEPCTSNVESTNSSPSENVGSLSPYAKSPWSSHMAI
SNPMFEESFSTKGSSYNCLMGSLIREEGHIYSLATTGDLLYTGSDSKNIRVWKSQREYSG
FKSNSGLVKSIVISDDKIFTGHQDGKIRVWKMSSKNPSIHKRIGTLPSFKAYMKKSIKPS
SYIDIGRRRNVWIRHLDAISSLSLSEDRNYLYSASWDKTVKVWRTSNFKCLESISAHDDA
VNAVVAGFDGLVFTGSADGTIKVWRREVQGKGTKHFFSQSLLKQECAVTALVIDPTSTLV
YCGSSNGQVNFWARNNFAFPAGTLNGHKLAVLCLATAGSIIFSGSADMNICVWRRIVNEE
MNTEDHVCLSILTGHNGPVKCLAVVASGETTSPDSRWLLYSGSLDKSIKIWRISEEVPNS
IISYTRSNTQQQGLSFAFR
>Sgl39517 E3_adaptor/Cullin_RING/DCX/DWD 46.9 9.8
MELKVKKKPTMAKTKQTDKTKKEKQKIAKERQKLAKEKRISDKKEEKKNQKLLKSKKKKT
SRDSLTKFNFDDKDDEKSQIPDYHEASEAESSGRRSSGSDVVSNDTRVNDANTSGNDDSD
AYHTAEESDSSEDEVPPRNTIGDVPLEFYNDEEHIGYDIIGKKIKKKDRIDSMAKLLAKD
DAKSWKKVYDAFNDEEVELTKQEIKMIRRISKGKTPHADVDPYAPYVDWFDWDGKGHPLS
NAPEPKRRFIPSKSEGKMINKYVRLIRKGVIKFDKPKEEPRFYRLWDDDSSSSVKTRGLS
YIPPPKAKLPGHEEAYNPSLEYIPTQEEINSYQLMYEEDRPSFIPKRFTSLRGVPAYESF
LKECFNRLLDLYLCPRKRKKRLNVELEEFKPKPPNPKEFKPYPTTCYIEYKGHTDAVVSI
STESTGQWIASGSIDGTVRIWEVATGRCVRVWEVGSAVRHVAWNPLPHQPVLAVSVDRDV
LILDTGLGSEEDQWKIRDLLKFEKHASPDESGDAGIVSWHFDDKLGGLRLKHFKAVSSIE
WHRRGNYLSTLIPSDILQFIFVLLFSIYSLLISFIIHLSYEVQTTEWLGSVVSDYIYMSD
YINVLYLMISATLLASCVFLTLFLRESRAIVIHQLSKKESQIIPFKLHGLPVSTAFHPSR
SVFFVATKKNVRVYDLLKEKLIKKLDTGLREVSSIAVHPGGDNVIVGSKEGKLCWFDMDL
GTDPYKSLQHHNKDITNVAFHHSYPLFASCSEDGTAYVYHGMVYSDLNQNPLIVALRILH
MHSGAKESGILDCKFHPRQPWLFTAGADSVIKLFCH
>Sgl39522 E3_activity/RING/RING 30.6 9.8
MGIMAETPNNGDFPCVILYCDKDNLNLTSCTVTCLPSVETFPLPSRPPPPPPSPSPPPSQ
SHLAPYLIAIVCILGISFLLLTTCTIILRYRFTRRREEDDHTISDNSGVNDDQPFVDHPI
WHITTVGLQQSVIDSITAFKYKKIDGFFVDDSDSFCSVCLTEFEDGDDLRLLPKCCHAFH
VSCIDTWLRSHKNCPLCRAPIVNEGLEGNSVVGNINSNDSGLRGESQRMNLDESDGGEGS
SHQFREIGDDLGRLPVLEGIKIAEILRKNRELRIFSDLGANHRFRGVEDGGLESVRRSVS
FNAVAALAKSGTMMSISNGGCSSDWSFNEGCSNGENSKGVLKQKKTDIEKGGGNKRGSSM
SGLLIKSSSSGRSLQKGPVSMKRSLSTSSRFFSFRRSKSQASILPL
>Sgl39526 E3_activity/RING/RING 38 5.8
MKTVHCSSTLFQISLLSLILISLLLHQAEAQKPPDSTISNDIDDELEGSRVSPSMAIIVI
MLVLGFLTTGCISIYIQQCSDNSSIGEALPVNGQPIRSVQRGLDQSVLDTYPTILYSDVK
ELKIGKGTLECAVCLNEFEDDETLRLLPVCDHVFHPQCIDAWLSGHTTCPVCRANLVPMD
NSPGSHSDEDSLNRLHPSDDNNNEVEIAVTTYPPKGKMPRSHSTGHTLVPLMRTAEDHER
FTLRLPDEVRKQLLAARPRLKRTTSMVALPRVSSSRRGYRSGGGGGEGSGSSRYGRFFVR
SFRWSTKNNNGYDGDTYTGSKRFFGTVVKPSEGLPRLPV
>Sgl39532 E3_adaptor/Cullin_RING/DCX/DWD 111.6 14.4
MFARSNSAQQQAQLYSDNNFENHQCEPCTSNVESTNSSPSENVGSLSPYAKSPWSSHMAI
SNPMFEESFSTKGSSYNCLMGSLIREEGHIYSLATTGDLLYTGSDSKNIRVWKSQREYSG
FKSNSGLVKSIVISDDKIFTGHQDGKIRVWKMSSKNPSIHKRIGTLPSFKAYMKKSIKPS
SYIDIGRRRNVWIRHLDAISSLSLSEDRNYLYSASWDKTVKVWRTSNFKCLESISAHDDA
VNAVVAGFDGLVFTGSADGTIKVWRREVQGKGTKHFFSQSLLKQECAVTALVIDPTSTLV
YCGSSNGQVNFWARNNFAFPAGTLNGHKLAVLCLATAGSIIFSGSADMNICVWRRIVNEE
MNTEDHVCLSILTGHNGPVKCLAVVASGETTSPDSRWLLYSGSLDKSIKIWRISEEVPNS
IISYTRSNTQQQGLSFAFR
>Sgl39562 E3_adaptor/Cullin_RING/DCX/DWD 48.3 9.4
MELKVKKKPTMAKTKQTDKTKKEKQKIAKERQKLAKEKRISDKKEEKKNQKLLKSKKKKT
SRDSLTKFNFDDKDDEKSQIPDYHEASEAESSGRRSSGSDVVSNDTRVNDANTSGNDDSD
AYHTAEESDSSEDEVPPRNTIGDVPLEFYNDEEHIGYDIIGKKIKKKDRIDSMAKLLAKD
DAKSWKKVYDAFNDEEVELTKQEIKMIRRISKGKTPHADVDPYAPYVDWFDWDGKGHPLS
NAPEPKRRFIPSKSEGKMINKYVRLIRKGVIKFDKPKEEPRFYRLWDDDSSSSVKTRGLS
YIPPPKAKLPGHEEAYNPSLEYIPTQEEINSYQLMYEEDRPSFIPKRFTSLRGVPAYESF
LKECFNRLLDLYLCPRKRKKRLNVELEEFKPKPPNPKEFKPYPTTCYIEYKGHTDAVVSI
STESTGQWIASGSIDGTVRIWEVATGRCVRVWEVGSAVRHVAWNPLPHQPVLAVSVDRDV
LILDTGLGSEEDQWKIRDLLKFEKHASPDESGDAGIVSWHFDDKLGGLRLKHFKAVSSIE
WHRRGNYLSTLIPSGESRAIVIHQLSKKESQIIPFKLHGLPVSTAFHPSRSVFFVATKKN
VRVYDLLKEKLIKKLDTGLREVSSIAVHPGGDNVIVGSKEGKLCWFDMDLGTDPYKSLQH
HNKDITNVAFHHSYPLFASCSEDGTAYVYHGMVYSDLNQNPLIVALRILHMHSGAKESGI
LDCKFHPRQPWLFTAGADSVIKLFCH
>Sgl39566 E3_activity/RING/RING 30.6 9.8
MGIMAETPNNGDFPCVILYCDKDNLNLTSCTVTCLPSVETFPLPSRPPPPPPSPSPPPSQ
SHLAPYLIAIVCILGISFLLLTTCTIILRYRFTRRREEDDHTISDNSGVNDDQPFVDHPI
WHITTVGLQQSVIDSITAFKYKKIDGFFVDDSDSFCSVCLTEFEDGDDLRLLPKCCHAFH
VSCIDTWLRSHKNCPLCRAPIVNEGLEGNSVVGNINSNDSGLRGESQRMNLDESDGGEGS
SHQFREIGDDLGRLPVLEGIKIAEILRKNRELRIFSDLGANHRFRGVEDGGLESVRRSVS
FNAVAALAKSGTMMSISNGGCSSDWSFNEGCSNGENSKGVLKQKKTDIEKGGGNKRGSSM
SGLLIKSSSSGRSLQKGPVSMKRSLSTSSRFFSFRRSKSQASILPL
>Sgl39570 E3_activity/RING/RING 38 5.8
MKTVHCSSTLFQISLLSLILISLLLHQAEAQKPPDSTISNDIDDELEGSRVSPSMAIIVI
MLVLGFLTTGCISIYIQQCSDNSSIGEALPVNGQPIRSVQRGLDQSVLDTYPTILYSDVK
ELKIGKGTLECAVCLNEFEDDETLRLLPVCDHVFHPQCIDAWLSGHTTCPVCRANLVPGN
NSPGSHPDEDSLNRLHPSDDDNNNEVEIAVTTYPPKGKMPRSHSTGHTLVPVVRTAEDHE
RFTLRLPDEVRKQLLAARPRLKRTTSMVALPRVSSSRRGYRSGGGGEGSGSSRYGRFFVR
SFRWSTKNNNGYDGDTYTGSKRFFGTVVMPSEGLPRLPV
>Sgl39584 DUB/USP 238.5 1.9
MLQIPLLLSVALWIFTVILRWSLKNEESKKTTASPEASMADFDAFRGDFSNSAPPMVVNF
DEFQGELSDSSPTMAMKPRYECAVCLSLTSTRCSRCKAVRYCTDQFQLVLGYSCDIFWSF
LILFLLPLHCSSSKCQIIHWRQGHKHECHPQDHSASEKDDFDENADSVEQCKTNDISSAE
YFSRMDDKNISQDRHDDVFDLPVPRLSTVTVASFDTGRSSCGENETLSSHIDATKMGHRE
DKINSMEMNASPGLTPNGAVNSVRKLKKKSRQDDRRKFRPSNSEHSPGSQQDKSDRTFGN
VSSSKAEEVLFVDNDGQKHSSYSVPPRRSVSNELSRNGLASSFQKVVHHFKASNQKKPSP
HDTLLGISANRNCKTIFPYDAFLKLYSSNEVELRPFGLINCGNSCYANAVLQCLAYTRPL
TMFFLQGRWKEEWCFICEFEELMLNGSKGYTPLSPIRILSNISHLGHGREEDAHEFLRYA
VDTMQSVCAELAGVVGPEREESTLVGMTFGGFLHSKIRCLKCNNKSEKYERMMDLTVEID
GDVRTLEQALRRFTASEMLEGDNKYYCNRCKSYKKAKKKLTIFQAPNILTIVLKRFQAGS
FAKLKKPVQFPEILNMTPYMSDSSDKDKHPQYNLYAVVVHLDVSSAEFSGHYVCYVKNNR
QEWFKVDDTVVISVDLRRVLSEEAYMLLYARDSPRPPVSGRKSYDGQSDVVNFEVRSKGR
HSSSDVSVDPWVRQHQSSKSGYAKDPSFVEEWVTSSVKSIPRADSSSEVSSLFSNSEEGT
CSTPSTKDSASVDDFSDYIFGRGSTARH
>Sgl39629 DUB/USP 240.7 1.1
MLQIPLLLSVALWIFTVILRWSLKNEESKKTTASPEASMADFDAFRGDFSNSAPPMVVNF
DEFQGELSDSSPTMAMKPRYECAVCLSLTSTRCSRCKAVRYCSSKCQIIHWRQGHKHECH
PQDHSASEKDDFDENADSVEQCKTNDISSAEYFSRMDDKNISQHRHDDVFDLPVPRLSTV
TVASFDTGRSSCGENETLSSHIDATKMGHREDKINSMEMNASTGLTPNGAVNSVRKLKKK
SRQDDRRKFRPSNSEHSPGSQQDKSDRTFGNVPSSKAEEVLFVDNDEQKHSSYSVPPRRS
VSNELSRNGLASSFQKVVHHFKASNQKKPSPHDTLLGISANRNCKTIFPYDAFLKLYSSN
EVELRPFGLINCGNSCYANAVLQCLAYTRPLTMFFLQGRHSKECWKEEWCFICEFEELML
NGSKGYTPLSPIRILSNISHLGHGREEDAHEFLRYAVDTMQSVCAELAGVVGPEREESTL
VGMTFGGFLHSKIRCLKCNSKSEKYERMMDLTVEIDGDVRTLEQALRRFTASEMLEGDNK
YHCNRCKSYKKAKKKLTIFQAPNILTIVLKRFQAGSFAKLKKPVQFPEILNMTPYMSDSS
DKDKHPQYNLYAVVVHLDVSSAEFSGHYVCYVKNNRQEWFKVDDTVVISVDLMRVLSEEA
YMLLYARDSPRPPISGRKSYDGQSDVVNFEVPSKGRHSSSDVSVDPWVRQHQSSKSGYAK
DPSFVEEWVTSSVKSIPRADSSSEVSSLFSNSEEGTCSTPSTKDSASVDDFSDYIFGRGS
TARH
>Sgl39650 E3_activity/RING/RING 33 7.0
MAFIQIPCCHNFFPIGKRVDVRIKYRVFERCTFVDDDENEFVTQFYPYNQGSETILAINP
YCPDCKFELSTLFELMSYSAVECSTVLGFIQAKVERRLLSQSQLELDHDNNDDLGDYSIS
LDFYRCFERTFDEVTVRAWLERHSSVDAIDEEPGDCTPASEEAIQSLERITLTTSRKEDG
SAATCAICLGLMMRKNNNNNNNDEVGRRMPCKHEFHEDCILKWLHTSHYCPLCRFELPTS
SSSSSKEVDSHELVIRDSDDVFTIDCSEQ
>Sgl39651 E3_activity/RING/RING 32.7 6.9
MDSIQVPCSHDYSTSGRIVDITITHQNFEEHVYHIEDGSDVRRLNPLNTQTTPMSINPKC
PQCRDSLIASFDSIISPQRTCTAVLDIVQETIDNLVSNNSDHDGALATLIMICFIKRRHY
HDYDEDSAMEWAERASFEEPFKAGFTPASPESIRALERITEISSSSDEEATTCAICLEQL
LKNKEEVGRRLPCRHEFHEGCIFKWLSISHYCPLCRFQLPTFSSIIPL
>Sgl39692 E3_adaptor/Cullin_RING/DCX/DWD 19.6 0.6
MSGYSGVVVSNHSLQSHFTQVELRSLKSKYTSVKNQNGKVTISDLPSILAKLKAFSQSFK
EDEIRGVLTESASDMNQEIEFEDFLKDGKIRVFKWPSMDVLVDENEAYIEVKDLHFSIDG
EHLVSVGNGGPCKIWDVASSKVVASLQKENDENFHFCRFSQSSERDQVLYTLTTRGKGVS
IISWNTKSWNRIAAKHITRDPVSAFNVSIDGKLLAIGTVEGGILIINSSKMQVQMTVKTA
HMGLVSALTFSHDSSVFIYEMKLPSLFDCLLCSYFSGVYPVMPEPPAIGGYEGVGEVYAV
GSGVKGLSPGD
>Sgl39698 E3_adaptor/Cullin_RING/SCF/F-box 19.4 0.0
MGKPRKTPIKTLNTNNNVVVSLPQEVQPNILTSLPVKSLLQFRSVSKTWQSIIDNPTFAY
THYSAAQTRPGSARILLSFSNSDRSRHYLYSTGVFGGRAVHHLTLPGDGTAQGCYFLPPV
KGLVCFVSSNNIYVSNPSTKKVRILPHCPTIYKKTNLNNSYLYKPYSCYSFGFDSFSRVF
KLLHVFGTICRNDNKLYNVESRVLTLKTPDHFSSESISWKKIESSFPYPYPFKSQGVFVD
GFICWVGMESQGEGNIVAFDLRHEKFRLIPSPPNGVSSKSKLENIEGDLGVMSFKDYDDF
SLELWVYKNNSSTWVKKDVGLQFALKKKKGNNTSFPTFLGNSFTGGMLLSQDVLLHNFVL
RALNGSSTCRERGVRITGLPGWLDFLDYKKVNFCTSQYVESIVPLDFVVRLGDFVVDLAA
VKHPKQPLVVKLLPHKEVEVKNVAKEWKIEELVFGDLKEFQKKNQPSSTMVEDAKRSVDS
KSNGKWVKKVKSTSTKNRLKRN
>Sgl39714 E3_activity/RING/RING 59.8 29.9
MAFTQIPCSHDYYPSGKQIDVLFKYRVFDRCTFVAGDGDTRIVTPFYPYNNGAETILSIN
PYCPDCKTELYALYASMTHSEEEWSDMLKLARDEIEAVVPRLLEVPDFADDDYLGSLHIS
VDFYRSVILDYDEESVREWIERVSFTSEEGPNCIPTSKEAIDALERITTATTSTTTSTCA
ICLEELFVTKDEVGRRLPCKHEFHEDCILQWLHTSHYCPLCRFELPTSSSSLSSSIDIES
YIPIGTRVDVQIEYRIFQRCIFEVDNGDDIVTPLYPYNGTQTTTLPINPYCRHCKAALTT
LFLSINYSEAACSSMLESIKRDLNELFSRDLHYCDLRYNLQAHFTIQYRAPYSEAALREW
EEVIAHLEMVELEQAATSYVSACYETTDPCLERMITATTTSITQGETTTCAICLDELFVK
KEQIVRRLPCKHEFHENCVFKWIRKSQNCPLCRFELPTFPSHEKDL
>Sgl39728 E3_adaptor/Cullin_RING/DCX/DWD 77.9 12.3
MIAAISWVPKGVAKSVPEVAELPSKDEIEELLQSGALDTVDGDHDDDEEEEMDTESIKEA
DEVALASVAAEALVKDTKDIAEAFKDLDMDNYDADDGDDGIDVFSKGLGDAYYPSNEVDP
YLKDKDDNDSEEEEDITIRAEDSIIVCARNDEEISQLEVYVLEETEDGPNLYVHHDIIIS
AFPLCTAWLDCPLKGGERGNFVAVGSMEPSIEIWDLDVIDEVEPSIVLGGIIEKKKKKKG
KKKSIKYKQDSHTDSVLGLAWNKEFRNILASASADKQVKIWDIATEKCSITMEHHTDKVQ
AVAFCHHVPQILLSGSFDHSIVMKDGRKPSHSGYRWSVAADVESLAWDPHTEHSFVVSLE
NGLIQGFDIRVASSNSYSEMKPSFTLHAHDKAASSISYNPSVPNFLASGSIDKTVKLWDI
SNNQPSCVASQNPKAGAVFSVSFSEENPLWLAIGGSKGKLEVWDTSSDAGVAKKYASSHS
KKP
>Sgl39802 ULD/UDP/UBQ/UBQ_PIM 80.6 0.4
MKVFVKSLKGNHFQIEVQPQHTVSDVKKNIESVQGANVFPASQQMLIYQGRALSDGTTLE
ENKVIENSFIVVMLCKSKNSSQESSVAAAAIPTPKTKSLSGEGATVAVAATPTYKNTGES
SVAAAAVPTSKSESSPKGSSVVESSMPTSKSKSSLGKGPVGEPTMPIVKSKVVQWKQPLC
TSMAPATPESPSVEASSAPPTPVTNASVPASMPIPVSVPVNASSISETDVSYQAASNFGA
GNGLESTIQHILDMGGGIWDRSTVERALHAASNDPDRAVEFLYAGVPEQAEAGKPMDPSA
ASQLPTRSTTIRPNISNADPLNSFPRGLSNLESDASPLDFLRHSEQFQALRAMVQANPQT
MQPMIQEFGKQNPNLMRLIQEYQADFQRLLNEPVQGEEGNILERFASAVPQAVQVTPKEH
ASIERLEAMGFDRSTVLEAYFACNKNEELTANYLLDHMHEF
>Sgl39863 E3_activity/RING/RING 27 12.9
MWSFPNTIPNLRLRKVSTEPNLYCAGSSDEDTGSSSSREEGLECPICWESFNIVENVPCV
LWCGHTLCQNCVLGLDWANLELPGHKLKLPFCVSCPWCSLVSFRCVYRGTLRFPRKNYFI
LWMVESLNGERAKSSSTVCDDSQRAFPSRISSHIGSVNNCSPRRAQPTQARHWLGSNLDS
HVAGDVNVERPQFSLHKSLDYFIHVLSKFPLVILFLVTIFFVLPGCVAILVLYVLISILF
AVPSCLVMYFAFPTLERLMREIIS
>Sgl39889 UBD/UBC-like/UBD_UBC 138.1 0.0
MASSSSSSSAQLRLMSDLKSIINEPPEGCSASPMSDDNLFVWSATIFGPDESPWEGGVFC
VRLTFSDHYPEKPPRVRFTSDIFHPNVYHDGTLCMDIIQDAWSPCHNVATILTSIQSLLT
DPNPSSPANPEAAQLFQHDPKAYNKRVRRCARDSIECS
>Sgl39929 E3_adaptor/Cullin_RING/SCF/F-box 19.4 0.1
MSFKGIVRELKEMKGGIGSLSRRGGEGGRHWRGRTRSHIAPDQPAPCLDEAEQGRWANLP
SELLLDIIRRVEVSETAWPARSVVVFCAAVCRSWREVTKEIVQTPEQCGRLTFPISLKQP
GPRDAPIQCFIKRDRATSTFRLFFGLTPSEDETDKLLLAARKIRRATSTDFVISLVADDF
SRASNAYVGKLRSNFLGTKFTVYDSQAPQDVTVKTNSRSSRRFHSKQVSPRVPAYNYSIA
TISYELSVLRTRGPRRLHCVIHSIPLASIQEGGSAPTPHSFPQSFDDQCPPSPSVQGKEQ
AINFSSTSLSEPPPTLTEDRLILKNKAPRWHEQLQCWCLNFRGRVTVASVKNFQLVAAIE
PHHNIPAAEHDQVLLQFGKIGKDIFTMDYRYPLSAFQAFAICLSSFDTKPACE
>Sgl39930 E3_activity/RING/U-box 92.4 0.2
MGTDVSEVQESPTRALGIRVHVSMCTQLLGLVDRISSVFVAIEAARPRCSLGIQSLVQLH
NAIARARELVQNCCISSKLYLAITGDAAKRRFEGTKNLLDQSLSELQSMVPMELKLQISE
ILDDLRDAIFIMDPCDELAGKALRAMLQQNVSPIESVGNSEIELLQFSASMLHLTSQKEL
LIEKRYIKRLLNDLKEGNSTKRKTLKYLLHLLRKYDKLIVQQQTKNDSAHHAEAYNSVKS
ESKSSGLSSHTDHASFLHWSEIPEEFKCPLSSELLRDPVVISSGQTYERSYIQEWFDDGQ
DMCPRTGMKLPDLSMTSNTNLRDSISRWCMEHVIENPKPRKVTAVYGSLENSSNSFRSNA
SSMKDIDLRIDASNLSFGSLDSSFSNISHANHSVNSIKELSVIHSPRFQFYHSVDDIRAQ
FLSNVRGLPWESQCTAVQDLCTYLTYYNPSCAFISSKNFLDPLILFLQDAFNKHDIKAQK
TGSQLFFTFLRSSRKESELLSDDVYALLASFLGTEAAAEALAIMELLSTKVSFSDFAASG
ALTSIFQVLKNNKKEFQEPALRILYKFSLSIDSSSCKLASDWVPILVPFLDDTSVAGICL
AILENLCKFEDTKCSIVETQGCIASIIKLLEDCSCEDQERAVDILLTLCSQREYYCHVVL
RECCIPALVKVSNSGSDKGKGIALELLRQLKEINFEEGEQECPPRSNVNVSEGHHHHMGK
NVNQKASKPSGFIRRLFKRK
>Sgl40007 E3_activity/RING/U-box 41.8 0.1
MGKKQHSKDRMYITKTEWATEWGGAKSKELRTPFKRLPFYCCALTFTPFEIPVCTRDGSV
FETMHIIPYIRKYGKNPVTGAPLKLGDLISLTFHKNSEGEFHCPVLNKVFTEFTHIVAVK
TTGNVFCYEAIKELNIKTKNWKELLTDEPFTRESLITIQNPNELDAKKVLDDFDHVKKGL
KIDDEELKKLESDPAYNINVSGDIKQMLAELGTEKGKQTALAGGGGSKAQQERAAALATI
LAARSRIVDDPKSNGKTENKQGYSIVDAASASVHGRSAAAAKAAPAEKTAARIAAHMAGE
RAPVNAKLVKSRYTTGAASRSFTSTSFDPVTKNEYEYVKVEKNPKKKGYVQLHTSHGDLN
IELHCDITPRTCENFITLCEQGYYNGVVFHRNIRNFMIQGGDPTGTGKGGESIWGQPFKD
EVNSKLLHSGRGVVSMANSGPHTNGSQFFIMYKSAKHLNYKHTVFGMVVGGLTTLGAMEK
VPTDDDDRPLEEIKINSVTIFVNPYAEPDEEEEKAKENKVEDEENEKVGSWYSNPGIGAI
DGGTAGGGVGKYLKARTAQAEPVAADTSIPAAGSTKKRKVGVVGGFKDFSAW
>Sgl40012 E3_adaptor/Cullin_RING/BCR/BTB 20.9 0.0
MSHESETGKDMKEGWRNLGVSQTIFEENEEEEDDDHGHEYEDDEDEDEDLQSLSSPPLSF
PFSSPSSPLQSGADAWTAATGKKPDVNIQVRGVCFNLHKDVLISKSGYFKRQLTTRVSNF
TLSPPLKITADTFNQVADFCYSNHTVITPSNVVSLSIAARLLEMDGKESLRELTETYFCD
VITVDRTLTCNVFRSCLLLLPEAEQTAFLASRCIETMLDDNDGDGAVSCADGLKMVSPEG
FRVIADSMQRRYTTSHDLLYRVVDLYFLVYNGKMSEDQKTQITSCIDCSILSAALLMHAV
QNPRMPLRFIVQAMLIEQLNTHRSLYSVLNSTTPTTNNNPSCSDSPATLGVILERDAALR
QVAQLRAAVDTTCSRIKTLEKELSGMKKLLLESENHKLGSKSNHRSILLDDNNQRRSSSC
RFNNNYSNKVERGERGSVSTSFLRFRRNNNNNNGHNYTTSDEFCDLKMGSSASCLESDNV
GNGDRNRNDRVMKRNFGQRLIRGLRNVFGVSSSTNNSKLKDSESDHHIGGRKGLVTDAGD
NQGATTRTIFI
>Sgl40019 E3_adaptor/Cullin_RING/BCR/BTB 32.2 0.0
MCKMEDGDHVVDNLVKEKIHPPPAPPLPSFPLTIANPKMVMTKSKAKVLSSSKHQCSVNI
ATRDLYDRLFDGAFRADVVVHTDTGGQISAHASILGMASPVIRNIIKQSKDKDRRRSFTI
RGVPHDAVRVFIRFLYSSCYNPEEMEEYILHLLLLSHVYVVPHLKRECEVRLENGLLNIE
NVVDVFQLALLCDAPRLSLICHRMILDNFKAVSATDGWNVMKEAHPILEREILATVAESD
ARQKRLFRKREERKMYVQLYDAMEALVHIYRDGCKTIGPHDKAPKKDKHPCGYTACKGTE
LLVRHYASCKLRVPGGCAHCKRIWQLLELHSRLCIDSTTCRVPLCRNFKDRIMKQNRKEE
MRWRILARKIVRSKSISGAPFFSLANST
>Sgl40022 E3_adaptor/Cullin_RING/BCR/BTB 20.4 0.0
MKFMKLGSKPDSFQSDGDNIRYVATELSTDIVVTVGDVKFYLHKFPLLSKSARLQKFVAM
ANQENQDEIVIQDIPGGPASFEICVKYCYGMTVTLNAYNVVAARCAAEYLEMYETVEKGN
LIYKIDVFLNSSIFRGWKDSIIVLQSTKSLLPWSEELKIVSHCLDAIASKASIDTSKVEW
SYTYNRKRNPSENGGEQLYNGVRKQLAVPKDWWVEDLSDLDMDLYKRVITTIKTKGRVSS
EIIGEALKTYALRKLPGFNKGMIQGGDLQKNQSLIENIVRLLPREKGSVSSSFMLRLLRA
SMSLGCGEMVRTELLRRIGLQLDEASVTDLLIRAPPDETTVYDVDLVENLVREFVMQESS
VQNNFHTEIDFQELKKPVIISDSSKGMVAKLVDCYLAEVSRDPNLPLSKFISISELVSGF
PRQSHDGIYRAIDMYLKEHPGISKSERKKICKLMDCRKLSVEACAHAVQNERLPLRVVVQ
VLFFEQARATTSSSSPGCRTPDLQRPARASLPGGSHGSSRSATTNTNTEDDWDGVPTTEE
LKALRGEIANLRIGGGDGPKSDAEKAAANKVKGLLMSKRLFSKLWSSKEKDGENSSSDTS
ESPASTNNAEEIRSTPNRNRRHS
>Sgl40037 E3_adaptor/Cullin_RING/BCR/BTB 21.5 0.0
MAHSIYRAIISTLLILVCLTTPYTTTALSQNYYAKTCPNVEKIVRQAVQKKIQQTFVTIP
ATLRLFFHDCFVNGCDASVIIQSTSSNKAEKDHPDNLSLAGDGFDTVIKAKAAVDAVAGC
TNNVSCADILAIATRDVVNLSGGPFWAVELGRYDGLISKASSVNGKLPQATDNLNQLNSL
FASNGLTQSDMVALSGAHTVGFSHCDKFSKRIYGFTPKNPVDPTLDAQYATQLQTMCPKN
VDPRIAVSMDPVSPRVFDNAYYKNLINGKGLFTSDQVLYNDTRTKNIVTNWAQSSSNFKK
AFAQSMIKLGRVGVKNSKNGNIRVKSEAQLKQNFYANTCPKVENIVKKAVRKKFDQTIIT
IPATLRLFFHDCMGCDASVMIQSTPTNTAEKDHPDNLSLAGDGFALSGMEVPSDVNINIG
DASFSLHKFPLVSKCGYLKKLISESNDSDVCNIEINDVPGGSEAFELAAKFCYGFNFEIS
TENIAMLRCVAEYLQMTEDYAVGNLVGRTESYLDEVALKSLSSCVSILLTSEKLLPMAEQ
VKLVSRCVDAMAFLACKDSQFSGVNKLESGIESANSVLSLQPKPIVEFWWAEDLTMLRID
MFQRVLIAMTARGFKQFALGPLLMLYAQKSLRGLEVIGKGKKKLEPKQEHEKRVVLETVV
SLLPRERNVLSVSFLAMLLRFSTWLETTVACRLDLEKRMALQLGQAALDDLLIPSYCLTG
DTLFDVDSVQRIMMNYLESEVEGNHLGYGAGEEHVSPSSNDLEKVGKLMENYLAEIASDR
NLTVSKFIGLVELIPEQARVTEDGMYRAIDIFLKAHPTLSDLERKKVCSVMDCQKLSREA
CAHAAQNDRLPVQTVVQVLYYEQQRLREAMNETTGGESTSSAGAIFPTKTLNFYPTNTPS
MEELLKVRRENEDLKIELLKLKMRLKEIEKPMNNIIDTNDIASVTNSPAKSFTSSAAVGG
GATDQKPPLPRKSFMNSVKKLGKLLLPADGVLTPTRRSKSAKGRRAHTVGFSHCDKFSKR
IYGFTPKNPVDPTLDAQYATQLQTMCPKNVDPRIAVSMDPVSPRVFDNAYYKNLINGKGL
FTSDQVLYNDTRTKNIVTNWAQSSSNFKKAFAQSMIKLGRVGVKNSKNGNIRVKCDAFN
>Sgl40040 E3_adaptor/Cullin_RING/BCR/BTB 24.5 0.0
MSSKNKELMSSAMKRTSEWICSQEVPSDVNINIGDASFSLHKFPLVSKCGYLKKLISESN
DSDVYNIEINDVPGGSEAFELAAKFCYGFNFEISTENIAMLRCVAEYLEMTEDYEVGNLV
GRTESYLDEVALKSLSSCVSILLTSENLLPMAEQVKLVSRCVDAIAFLACKDSQF
>Sgl40080 E3_activity/RING/U-box 29.6 0.0
MASGFEESMKAEPSSSNGGANNNDAGDFECNICFELAQDPIVTLCGHLYCWPCLYRWLHH
HSQSQECPVCKALVEENKLVPLYGRGKSTIDPRTRPVNGDDIPNRPSGQRPETAPSPPGP
DQNYFSNLGFGFLSGFMPMATARFGSITMSAGFGGMLPWSMMSAQFNGFPHNPMYGAAHG
FPFGYQQTVHGNRMHHAHGHGFGHTHEFLHQEGVARQGQGQDSLVKLLFIIGFLVFAALA
LCDFSW
>Sgl40091 UBD/Alpha-Helix/UIM 23.3 7.8
MGWLSKIFGGSSHNHRISEGHHHGRYGDDSTWDGPTTSGGELSDYDNEDIDRAIALSLAE
EEERQQNKDKKGKKVIDHESNENHMEEDELLAKALQESLNMESPVQTPPQTPPQPPPQYD
RGHMWQPYPFFSYGYRTCSGCGAEIGHGRYLSCMGGFWHPECFRCQACNEPISDYEFSMS
RNRPYHKACYKEQHHPRCDVCQNFIPTNAAGLIEYRAHPFWMQKYCPSHEYDRTPRCCSC
ERMEPRDTKYLVLDDGRKLCLECLDSSIMDTNECQPLYIEIGEFYEGLNMKVEQQVPLLL
VERQALNEAMEGEKQGHHHMPETRGLCLSEEQTVRTILKRPKIGGGHRVMDMITEPYRLV
RRCEVTAILILYGLPRLLTGSILAHEMMHAWLRLNGYPNLRPEVEEGICQVLAHMWLESE
ILAGSSSSSGASSSSSSGSSSSSSSNSSKKGKRSQFEKKLGDFFKHQIESDASPAYGEGF
RIGNQAVSKYGLRRTLDHIRLTGTFPC
>Sgl40108 E3_adaptor/Cullin_RING/BCR/BTB 18.5 2.7
MATEKSGTSTPSKGQAWFCTTGLPSDVVIEVDDMTFHLHKFPLMSKSKKLHDLIKEQEIK
QVSKQRQKQIRETDDIESSEEDEEVPEEEQCHVSFSHFPGGTETFETAAKFCYGVKIDLT
AAKVAPLRCAAEVLEMTEEYSEDNLISKTERFFTNSVLKNIKDTIKALISCENLSPLAEN
LGIVERCIDAISSKASLYDPSLFGWPVNDVTVSTASDSRKKNVTSSKLRDAWVDDLAQLS
SQLFNRVISSMREKEITPEVVESCLIHYAKRCFPGISRSNRKRTSSSTMMASEAEQRQLL
ETIISNFPQEKSSKSPAVTSFLFGLLRTANILNASDACKSALEKKIGGQLEQATLDDLLI
PSYSYLTETLYDVDCVQRILGHFLATYEETTDNVEGVDQTLGNVRSPAIMLVGKLIDGYL
SEIASDSNLKPSKFIELALSLPQKARLYDDGVYRAVDVYLKAHQWLSEDEREKISGVMDC
QKLTLEACTHAAQNERLPLRAVVQVLFFEQLQLRHAIAGTLLTADAAASESPRPSAQDEE
AEEEQEDTAVAGRETGNNHTWREAVRENQVLRLDMDSMRTRVHELERECSTMKKVIQKID
KVGTSQTWRSSLTRKFGCKFKTQVCDSHESAVVEARKGRHHQSNQR
>Sgl40118 E3_activity/RING/RING 30.4 10.5
MEFYSYPSQQIATSSSILCNLGEKIRGTLSFALSATLGSLFSAIFTFCFALVGTLLGAMT
GALIGQETESGFVRGAAIGAISGAVFSIEVFESSVVLWRSDESGIGCLLYLIDVIASLLS
GRLVRERIGPAMLSAVQSQMGAVETNFEDVTNIFDTSEVKGLSGDLVDKIPKIKITNKNN
IDASGERVSCSVCLQDFQIGETVRSLPHCHHMFHLPCIDKWLLKHGSCPMCRRDM
>Sgl40127 E3_activity/RING/RING 27.7 11.6
MTASTSNTDAQYKYKMTALPVTKLAYDGARRSASDVNSSSLLMKIKYKVYLFHKSSHINN
INDDDNPDAVVRNKVRTRRMSVRYSVPWRHLISDDDDGNPNSNSWSKMSEVITHASSYIP
FPQSTLYWTDYQDRKKITPLDNQNQMITRILQTARSMVSQPTDSEAIHNNNYNNTSYQLN
LCLKKEIYLDHDEYVTRVCQSELDYRKWNIIRRCINRLQPPLETETVRRELIACLRAGGI
NNQIHDGGIDRLTNWVMMLFSGRSIRESMWHTTKPAAEDVIKNLQSHILDSDEVCPLCLE
TMIEGDVVNQLPCSHVYHPDCIMKWLHQCNSCPMCRFPMPI
>Sgl40128 E3_adaptor/Cullin_RING/SCF/F-box 12 0.0
MDKGKNQAKSGAVSKPNKIYMDLREIIQEHALRYLPAKSLYRFKAVCKDWKLQISTPFFE
HSQSVSFSSLSGLFWQYPDGSISFIPLDPMAHGVLDPELKFLPELVDVLSSSNGLVCCRG
RSGEKAYYICNPVNQQWKKLPKHEADHGQHLSPVLVFEPSLLSFVAEYKVICAFPSTDFE
GAYEFEIYTSTKDLWEISPEICFGENGRILKSGGLHVNGVVYWKSNNYALIGYDLKKNRV
KVIPTYELGGSFTFGIMDGKVCASSMKSSMVTRCLLSNEYANTMHMISESKTWEKRTTML
SHVRISDEAILLAVGGDTIVFSEGRQFFCHDLRTKETKRLMTNVEYNLLNFYVPCVNSLV
RLE
>Sgl40183 UBD/UBC-like/UBD_UBC 90.5 0.0
MTASSATSRKTLSKIASNRLQKELAEWQLNPPTGFKHKVTDNLQRWIIEVNGAPGTLYAN
EIYQLQVDFPEHYPMEAPQVIFMQPAPIHPHIYSNGHICLDILYDSWSPAMTVSSICISI
LSMLSSSTVKERPEDNDRYVKNCRNGRSPKETRWWFHDDKV
>Sgl40192 UBD/UBC-like/UBD_UBC 90.5 0.0
MTASSATSRKTLSKIASNRLQKELAEWQLNPPTGFKHKVTDNLQRWIIEVNGAPGTLYAN
EIYQLQVDFPEHYPMEAPQVIFMQPAPIHPHIYSNGHICLDILYDSWSPAMTVSSICISI
LSMLSSSTMKERPEDNDRYVKNCRNGRSPKETRWWFHDDKV
>Sgl40223 E3_adaptor/Cullin_RING/SCF/F-box 14.7 0.1
MSCRRVSWSDFPLELLLKIVGCLQSRSDIQNFRAVCKTWSRSISSSFVTSRNILSPLLPH
SLRPSSRYDSYWLDSDSSRQSPVLVATHVFLFRSITAPTASPWLFTAEELHPRKLFVSKL
LSPIAIETFPTDFPKTIDLSYIQVSELAAFHRLRFVDDATDMFTTKNLYDFNDNRVVLFK
NPKCTKTCPSISDCTAMILHHNGALCAMRLRNGKELPLGSTRKFDDIVNFKQKIYAIDRK
GRAYMMDYGSLSLTDFIREPLNEVYFEKRKRLAVSSDCQELYLIYRWCRSKTSDVVAFNI
YKLNEKERKWDEVGGIGDDMILFVTFDGCFFVSAKDFQGWKGNCIVFYSACFASYSVSSL
TNRDRVISLSVYDFEDGDCQFLASYQSKLLWPPPAWLSSPACMSKRKLEQDEVMQPGSSC
RPSTEPLDVQNHVTMNNVRNVAGEAEESMRSITSSEIFKSSASDTSTVKFKGLEVKCSSV
PMLHRIWSRHGNIIEKTCISNGDIIAKALESLANVVLILEGSTGKTLNDREADYLKSTLS
DLRHMNFNIDWLANSVEKALALHKSKPMVKPLNNLLKVKAQAVEIRFRLMEKLDRVEKEL
DEGIALARRKVPFSEREFEQSLGKGLV
>Sgl40229 E3_activity/RING/RING 35.1 7.3
MVCIMVNKFKSCFFPSKIRKFQTMNCFGVRDHPSESFHGSNNSVNCLLAPLQCILQKIKE
LFMVTNGRLHIRSSQQQAASVEASATSEIRVNSINYTLVRLEYQNLEQIQDMIRADRRVA
MCNMSNDCTQQTQTEAISDTNESSKTMTSVDTENPSILPKFEVLYDNECPTCLEEYEAEN
PKIVAKCSHHFHLSCIYAWKERSDKCPMCLQVIYYLSFFLLNYVYICC
>Sgl40264 E3_activity/RING/RING 30.6 11.6
MKNFYNKLTIILPLISLHYLCVPNVSNAQCCAAVGCSYNDRISIEYPYRLKGVQSDSCGC
QGFDLYCDDEQQGLILELPNAGNFTVGYIFYYSSTKKIIISDPNDCLPQKLLALDLTTTP
FRGIGQSVDYKLYNCTANAVYNLDRYSDAIDCLSGSGYTVIGVSSSTIVSDPYCTFLGNV
SIPTEYGFSRGLTTYSRIHLTWDDHGCKSCIDQKTRWGAILGISLSMSIALVLFCYISIR
LYLISRNDSRTSRIINSSATTTTTTENAPTSSGLDQVTIESFPVVVVGESRAVIKHDNNM
CPICLSEYSPTDTLKMLPHCLHCFHADCIDVWLQTKPTCPICRTSPSQKS
>Sgl40316 ULD/UDP/UBQ/UBQ_Other 34.6 0.0
MSKLDSPVQTQVPVGVFKNPLSGQFHGKQPTTGRRRVFVQTDTGSVLGIELDRSDNVHTV
KRRLQNALNVPTDESSLTYGDMVLKNDLDAIRHDSPLLLTRSNMHRSSSTPCLSPRGGDL
QQKDKSGLIEELGRSDRFCVTKQMVKEIVKGIKNGVEPLLVQSGLGGAYYFRNVRGENVA
IVKPTDEEPFAPNNPKGFVGRALGQPGLKRSVRVGETGIREVAAYLLDRQHFASVPATTL
VKITHSIFNVNDGVNNKAHKKMLVSKIASFQQFIQHDFDASDHGTSSFPVSSVHRIGILD
IRIFNTDRHAGNLLVRKLDGVGRFGQVELIPIDHGLCLPECLEDPYFEWIHWPQASIPFS
EDELAYIESLDPDEDCEMLRSELPMIREACLRILVLCTIFLKEAAASGLCLAEIGEMMSR
EFRSGEEEPSELELVCIEARRLVEERELYVPESEAGEEEFQFDIDCDFPDWDCTPKMAFG
EDYLTRSPGLGMNGRSPLSKLEESLDEEEEESEDGDIEGVRKTDVSSAFPILEKFPSMST
ISMSLKNTSLGEKKFPAMKPENGYSSSGHRSANEQLPASASFVKVADMNEEEWALFLEKF
LELLRPAFDERKSVTLGQRQRQRLGTSCQF
>Sgl40360 E3_activity/RING/U-box 94.2 0.0
MDRIETIDCMNHRVCEWKGLVNYTNSLYLLCISQSNGEVKHDLSIVKPLLALLSEITASI
SSLKIERINFVQIGSYFYRTASAITELHTSVNNSANEAKILQSLSQSSELAKSILVKLQQ
SEKTILDDEVRNMIKQLEEIVNHMGHDLSLIPTSSFIDEEHAEITVCSLSEEMKQAQFDI
SPVQETKINEQQTEPLHPKEHPQEDSIPIGSDLYSFSSMMVSTENSHVKDISQLVETIRS
TSQSSQSSRAKMNNRLSRSVKEVGQHMEPMYKSFICPLTNEIMEDPVTVSSGVTYERSAI
TKYFEEFGDLEEVTCPFTREKLKSKALSPNIALRNIIDEWKDRNDSAQLKVIRAALSIGS
TDSMVLEALKDLQNICQKSPIKKKEVHSLGMMPLLVKLLELRDRVVRCTALEMIRSLVEE
DEAKEEIAKTLAIPTTIKLLSSSYQPIRHAALLLLNDFSKSKLLSEKIGCVTGGILILIQ
TKYNRSIDTFASEAADQILRNMEQCSINIKLMAENGYLKPLLDNLIEGSEERKLEMMTYL
GEIILEDDTKTYVAERISPVLIQMLQNGNPSTRKTVFKALAQISSYPASGKILVEAGIVG
NMVEEMFTKKIYSEPMDSLKDASAILANILESGIEFENLIINSQGHTMVSGYVVFNIIYM
IKNSTPDDLNFNLLRILHSMAKSKKSNAQVISAVKESEASYTLVELVNNPSDDIAVAAVK
LLTLLSSYIGHLLIDRLCKTNGQPEGLIQSASDSSQITERQALSVSFLAKLPHQNLTLNA
ALLSKNTVPEILQSISQIQRNGTRQNRYASMYLEGLVGVLVRFTGTLYDPQMLFLAIDHN
FTAVLTDLLTETSKDEVQILAATGLEKLSAQSLRLSKPPAPSPRNKKQSCNPFRSKSPKK
AKVELCLAHKGVCSEQKTFCLIEAGAIERLLACLDNQNVQVAEAALSALSTLLDDKVDVE
NSVFMLSELDATQRILKAVRIHKNETLWQRAFWMIEMFLVKGGQRPLSLVSQDKLFYITV
VTAFHHGDAYTRQMAENILRYLDKMPSLTGTFNT
>Sgl40373 ULD/UDP/UBQ/UBQ_Other 34.6 0.0
MSKLDSPVQTQVPVGVFKNPLSGQFHGKQPTTGRRRVFVQTDTGSVLGIELDRSDNVHTV
KRRLQNALNVPTDESSLTYGDMVLKNDLDAIRHDSPLLLTRSNMHRSSSTPCLSPRGGDL
QQKDKSGLIEELGRSDRFCVTKQMVKEIVKGIKNGVEPLLVQSGLGGAYYFRNVRGENVA
IVKPTDEEPFAPNNPKGFVGRALGQPGLKRSVRVGETGIREVAAYLLDRQHFASVPATTL
VKITHSIFNVNDGVNNKAHKKMLVSKIASFQQFIQHDFDASDHGTSSFPVSSVHRIGILD
IRIFNTDRHAGNLLVRKLDGVGRFGQVELIPIDHGLCLPECLEDPYFEWIHWPQASIPFS
EDELAYIESLDPDEDCEMLRSELPMIREACLRILVLCTIFLKEAAASGLCLAEIGEMMSR
EFRSGEEEPSELELVCIEARRLVEERELYVPESEAGEEEFQFDIDCDFPDWDCTPKMAFG
EDYLTRSPGLGMNGRSPLSKLEESLDEEEEESEDGDIEGVRKTDVSSAFPILEKFPSMST
ISMSLKNTSLGEKKFPAMKPENGYSSSGHRSANEQLPASASFVKVADMNEEEWALFLEKF
LELLRPAFDERKSVTLGQRQRQRLGTSCQF
>Sgl40433 E3_activity/RING/U-box 104.9 0.3
MDIAELEESLFAISDAKLHGGMCKLFYNVYCKVLNIFPDLEASRPRSRSGIQALCSLHVA
LEKARNLLQHCSECSKLYLAITGDSVVMKFEKAKCALVDSLRRVEDIVPQTIGCQVQEIV
TELEETMFSLDPSEKQIGDDIIVLLQQGRKFDDSSSDNCELESFHQAACKLGITSSRAAL
AERRSLKKLIEKARIEEDKRKESIVAYLLHLMRKYSKLFRSDLGDDQDSQGSGPCSPTIL
GSSEDGLAGCNGRAFDRQISKINSFNFRPSFSFRTNRRPEQMPIPPEELRCPISLQLMYD
PVIIASGQTYEKICIEKWFSDGHNTCPKTQQQLSHRCLTPNYCVKGLIASWCEQNGVLIP
SGPPDSLDLNYWRLALSESESAQPRSEDSSNSGSIKGVKVLPLESDIAEEYEGNEGECCS
TEQEVSDENVFGKCENYLNVLQGEDDLRFKLKVVEQIRRLLKDDEEARMFLGAQGFVEVL
VGFLKSALAEKNDLALEVGAMALFNLAVNNNRNKEMMLAAGVIPVLEEMIADHDSHGLAA
ALYLNLSCLDEAKPVIGSCKAVSFLINLLVGTSDPQWKLDALHALFNISSCPANISNLLK
SGIINGLVLLLVEPRDHAWTEKSIAVLINLASNNTAKDAITSAPGLVGALASIMDMGEPI
EQEQAVACLLILCNGNDKCCQMVLQEGVIPTLVSIQVNGTARGREKAQKLLMLFREQRQR
DTSPQRVHRSPSVREFNGQVQPEDMKPLSKSISEKVMPGLEQKPLGIPGDGSCLFRAVVH
GSCIIQGKPAPNEGLQKELADELRDKVVDELIKRRKDAEWYLEDEFDRYIRRMRQCHVWG
GEPELLMASHVLKMPITVYMCDKMSCNFKIIAEYGETYGWQNPIRILYHGYGHYDALRSN
P
>Sgl40456 E3_activity/RING/U-box 25.8 0.7
MVTENSSKQTPKTNKTPLNQPQNSSENRSNSMSLISPRFKSVAAMAGWDEEALLLASLVV
EDTPERILKEKRNSDLNHKSPLSNSNNNYTSRRKRRRSRVVSIPVLNLEEDDHHQSSNTN
QKEIEKGKIDLLKKIEDEPKEEKEKEESANCSSSSTLACMDRLKDELSCAICLEICYEPS
TTTCGHSFCKNCLKSAADKCGKRCPKCRQLISNGRSCTINTVLWNTIQLLFPQEVEARKA
AAAAAATLSTSSSKAAEERRKGLGARMLNASNHSNNDSNLNVSRRTRVSRRLEEASVSRR
RGVPDQDEDAALALRLQREEFMEIYRSDSSLARDNLRAMARRAMNVPRNRGNT
>Sgl40496 E3_activity/RING/RING 26.3 10.9
MWQKQPTKSSYRESIKALEADIQHANNLAASLPRDYCGDSIQMRLSYSPLAPFLIYLIEW
MDYSCTDALPSFLGLHHILVYKVYVDGMPTMSSQEKRASLREFYAVLYPSLRQLEGNLIE
LEESNKKHRNLDVLSRNKVDDKRKLLDKDLERDDECGICMEPGTKMVLPTCGHSLCIRCF
HDWNSRSRSCPFCRGSLKRVNSKDLWVLTNNHEEKEDDYNSNNNKANTKEANH
>Sgl40498 E3_activity/RING/RING 21 14.9
MEMVYYQLGRSSYQELLKELEADIQHANALVTAIPKPKKGVCLHMKLEYNQLSPLFFLLL
QWLDGSCSCFFPLYFNLFHILIYEVYPDGRTHMPAQGSRATVKEFYAIILPSLRRLHNDL
VEQQSTSHLTKKSNEKKQLIGLQNGIDQEREEECGICLVPTTKMVLPGCCHAMCINCYRN
WNRKSESCPFCRGGLRRVKSEDLWVLTSESEIIDAETVSREELSRFYLYIQSLPKDSSDF
WVYYNYLT
>Sgl40539 E3_adaptor/Cullin_RING/DCX/DWD 106.3 6.8
MNLKNRFCLCSSASAVVEDGGDTTDDSTLSVSPTASPASNMTGHSSLTSHLSLQTLPSVP
SLQFFSLLETSLTVTVTHTLSTSLSLPSSISSLSLSKNLLYVSSGHQINVYDSSTLSLQH
TFNSDGTSTGAVKSIVFYDGKVFSAHQDGKIRVWKLTEKKHKLVSTLPTLTDRLSRFPLP
KNHVKVRRHKTRLWVEHNDAVSSLAVAKNGNIYSVSWDKTLKVWGPKSLRCRESVTAHED
AVNAVAVASDGIVYTGSADGRIRVWAKPEPGTGRGHASVATLEKHKSAVNALALNSDGSI
LFSGACDRSILVWEKEDNAKYMSVSGALRGHDGAILCLINVSDFLISGSADRTVRIWRRG
NEGKYCCLSVLTGHTKPVKSLAAKMEGDDGISVFSGGLNGEIKVWSLKINYTSSNDL
>Sgl40585 E3_activity/RING/RING 28.3 15.0
MGLSNFPSPAEGVLPILVMNTVMSVAILKNLLRSVLGLIGAVNWVSRENQSSSSSTTTTT
TTTEIDQSLSSQPNRGKRMRGVSITQFKCLCNQSNTNSKSESGNGNSKFSLEVEVEVEGR
TTIECCVCLCKFEDEDEVSELSCKHYFHRNCLDKWFDNHHTTCPLCRSIH
>Sgl40636 E3_activity/RING/RING 19 4.5
MECLHRFCRECIDKSMRMGNNECPACRTHCASRRSLRDDQRFDQLIAVLYPDIRKFEEEV
MYELEDVDLQKICYEVPPKRKKKSIEMAFYDEDEARNKQIQESITQVLIKQSEALGKKRS
SNKDAAGPSVTRSQR
>Sgl40639 E3_adaptor/Cullin_RING/SCF/F-box 16.9 0.0
MKQKTWPSRSDGSPFTALPLSKSNHHHQPPQSSRNFHSKPPFFLDRPIKSRATTDHRDFS
SLPYDLLTRIASPFSQRDLNAASLVCKSWNDALRPLREAMLLLKWGKRFKHGRAGVGPNM
EKALDSFLKGVARGSSLAMVDAGLVFWEMGRREEGIALYRRAAQLGDPSGLCNLAIAYLQ
ADFANPKEAVKLLLQSSSAGHVRAQYQLALCLHHGRGIDRNLPEAAKWYLRAAEGGYVRA
MYNVSLCYSVGEGFAKSHPQAKKWMKRAADHGHSKAQFEHGLNLFSEGELSKAVVYLELA
SRAGETGASHVKDVIIQQLSTASRDRAMRLAENWRALPSSR
>Sgl40686 UBD/Alpha-Helix/UBA 26.4 0.0
MIPLRFRLGGAAGARLFSNPGTNDNSTETHQGGDVHGCTDGEKGRDPTLHDGGENVRFAE
DCDTTNHTMMQYEEEQVEPVFSPPSYQVRKVQAAGKYSRLRKEEGRGGEKDSLKMTLGKR
KECSDNCEMEVDEVTKKALDMDNDGNSNSTSAKGKEIMIVDPDKDNLLDDYYCWDTDDEL
EIEYLKETLQMKDTEATSTSSSSSHKSPKVEYFISMGFKEKDVVQAIKESGEDNDDAILN
SLLTYSMQVPENSLGGDPKPEDDISLDGFSDSDSDTKVVLENSHGGDPRPEDDISLDGFS
DSDSDIKENGAESDHKDNTISILVDMGYEIEDALIALERCGYETPIEELADFICAAQLAK
TADVTEFVAPTRTVKSHEEKKRKAFPISRVNEWQIKRPIKRERIQRTEESSSRKLMIGYG
VPGCMPAVSYRRLPDHLNGPPYFYYENVAIAPKGVWNEISQCLYGIEPEFVDSIHFSAAA
RKRGYIHNLPIAGRQPLLPIPPKTIHEAIPDTRRWWPSWDNRTKLNCLLTCIGSAQLTER
IRQRLTSGEPSEADKQFVIEQCKKWNLVWVGKNRVAVLEPEDMEMLLGFPRYHTRGLSRT
DRYKSLGNSFQIDTVAYHLSVLKTMYPKGLNVLSLFSGIGGAEVALHKLGITLNNVVSVE
KENASRKVLQDWWEENGLKGRLIHFDDVQKVNEAMLDRWMDELNGFDLVIGGSPCNNLAG
GNRRTRDGLEGEHSSLFYNYYYILTYVRESMMKRRA
>Sgl40715 E3_adaptor/Cullin_RING/DCX/DWD 89.3 13.7
MDLLRSYEDEGEENPSLHSQNFESHNNKQLAKNEGGEEEEEEESSMISLPSKSAAPKVDD
TALSLLSSSSSASSKSKPLDPTQHLVNYNPTFDQLWAPIYGPAHPYAKDGLAQGLRNHKL
GFVENAAIDSFVFDEQYNTFHTYGYAADPSASAVNNFVGDFNALEKNRAVSVYNIPQSEQ
KRRRIEKKKGGDEVEEDEEMGVDKEEVENPASESWLSKNKVSPWAGKKEGLQGELTEEQK
KYAEEYAKKKAEERGEKVEKGEAVVDKTTFHGKEERDYQGRPWISPPKDKKATNDHCYIP
KRCVHTWSGHTKGVSAIRFFPKYGHLILSAGMDTKIKIWDVYGSGKCMRTYMGHSKAVRD
ICFSNDGTKFLSAGYDKNIKYWDTETGKVISTFSTGKVPYVVKLNPDDDKQNVLLAGMSD
KKIVQWDMNSGEITQEYDQHLGAVNTITFVDNNRRFVTSSDDKSLRVWEYGIPVVIKYIS
EPHMHSMPSISVHPNTNWLAAQSLDNQILIYSTRERFQLNKKKRFAGHIVAGYACQVNFS
PDGRFVMSGDGEGRMWFWDWKTCKVFRTLRCHEGVCIGCEWHPLEQSKVATCGWDGLIKY
W
>Sgl40724 E3_activity/RING/U-box 94.4 0.1
MIYNLNESTRRILTFPAVKPSESISITTLFNSLLSITKQISNFNESHFVFTSNKRNAKNA
LRFIQALRVFLEGVRDEGGFDKVGKYVISPLLDLHVALQKVNFLFEDCTRQDARVWMLMN
AELVSGHFRALIGSVGASLDHVLPLLRCDDEVQELGLLLIHQGKRAQFEVQMEDIWASNL
VKFALGRFESRVIPDPSELRRVLSYLGIKKWVDCNNQVKFLEEETGSGSVPAASLMGLMM
YCRCVLFDRIDCDYKRALGKKYSYNSGYLNPDDIKCPISLEIMVDPVTISTGQTYDRVNI
VKWFKAGNMVCPKTGQKIQTIDLVPNLAIKEVIKQYCLENGVLYPIPKYMGSSKRRNNII
QVVDNLVVQEATRMVADFLSLKLAMGTMGEKSKAAYEIRLLTKRSMFNRACFMESRAISY
LLNLLFSKDSVAQENSMAALLNLSKHPENKPVIVDNGGLSMIIRVLKSGIKMEARYHAAG
TLFYLSSVEEYRGVIGNNPDAIPSLVELVRVGGDQGRKNALVALFSLLLLPSNHCKVLEA
KLVSILVSLLGSVETSEDVIVDSLALLAALAEKPDGARAILHAKALDVITRMLCSPSLDS
SRIGREHLVSLLLTMCINCRGEVVDVLVKNTFLMRALYSLLVEGTSRASKKASSLISILH
EHSERRSVHPMPRALPHENFINVW
>Sgl40771 E3_adaptor/Cullin_RING/SCF/F-box 13.4 0.0
MSNSSIVYHHEAMEHNENKDRLSSLPDDILLSILQLIDIDEATRSSILSRRWRYLAPYSY
FTSLDLDANKKKALVGYKNCPISYKDGKPKFVNWVNQLVTLHRAPFLNDFRVCFPLLESD
SDCLCMWIRFAISKGVKKLELVFCSSGGFDYSGSLPLTPRCSFPSNVFKVDNNNNNNVFS
NNLLTSLCLRFVNISGELLELVLSRSHLLERLYIEGSNDLVNLKINNTSEKLKHLSIHRC
NFLQEIAIHAVNLVSFELSHSHKDLARFRPDSVKVVYASVPSLVDARFYWLDYYTFFPYF
SQMHGFAAQLTKLSLEMNMRVSREPNLPSFSNVKSLELRVTFGHHSFDWRHMNPLRLRRY
VKACPILEYIKLQVNWSCDCDRRQCEKELQLSDFESDDSDFELDDDFDMDSGSDEYEYSL
EDVRQWLERKEEEGFNGTLPFLRKIEWTAAFSNHFEAEYQLALYLIKNAVNLEKFICDPR
YHVNWSHHEAMIFKDDYFEDVCRLRATKLAMVIPSSVDFTIL
>Sgl40773 E3_activity/RING/RING 32.7 9.1
MTLLWCDIFIPVFKDKNYIYFLGFSSTMSLVESPSSSSLNNHDFFQRDTTSQSPESSSNS
GGKISPAILFIIIILAVIFFISGLLHLLVRFFIRKRSSSSSSFSQSNRYPDNISTSEGIQ
RQLQNLFHLHDSGLDQAFIDALPVFQYKEIVGLKEPFDCAVCLCEFSEQDKLRLLPLCSH
AFHIDCIDTWLLSNSTCPLCRGALYTPGLAIENPVFDFDESREDDTGGGGDCNGHHKGVE
IEIVSEKSKRVFPVRLGKFKSTSNSNINNSEVVHEQVLQRDVGETSSSNLDARRCFSMGS
YQYVVADSVMQVALCPNRPSNGGAESKIIKGRGGQNGNFTCNIRDDDDDVEARKINNIGT
KNESLSVSKIWLWSKKGKFPNSTNATDFSGGFPVDMNLPWTNRGQAT
>Sgl40802 E3_adaptor/Cullin_RING/DCX/DWD 26.4 10.8
MFVKKFVEKAIKKPGETLESLKPEDVDPRLAFHYGLPSSAAMLAHDPVQNILAVSTKNGQ
IKLLGKDNTQALLESNDMQPSKFLQFIHNQGILVNVTFKDQIEVWDIDRKMLLHVHDFNE
EITSFSIMQHCFFIFIGDSGGNVTVWKINKELSQFEKMNYWIPASASYGYTNKDAVDHAV
MYILPQPTLETKRILIIFSDGLITLWDIPESKAVFTTVGNEAMTHLASHESKRVTAASWV
CPFGSKVAVGYDTGDILVYTIPNSSLSRDSGNTQNVHTSYKINLGYRLEKTPIASLKWVF
SDGKVNRLYVLGASDATSTNLVQVILLNDDTESRTTKVGLQLPEPCHKLEIISSLKDQSK
HKQQFLLLIGISGLMYAYDDHSVEKSLLQSQSKSSVSLPSELIIKLPFSDSKITSAQFIT
NQSSNIDFKQEDYMVIAKTIPCVLPSEAKNISSPHFTGFSKVTNLYITGHNDGTIKFWDV
TCPLLIPLLSLTQQNEDDSSQSDIAVTAIQYCSALRLLFSGDKSGMVRIYQFKPEPFSIE
NAFFSLQGSTKKGNNHIIHSVKFIKVNASVLSFSINSSSKYLAVGSEQGHISIIDIESSS
ILYQKQIGTELSSDVMSLKFETSDNHGFEKNILVIATRDSSLLALDADTGSTLSSSAVHP
KKPSKALFMQTLETTSGSSTEEATQKQQLLLCSEKAVYIYSLPHIVQGTKKIFYKKKFHS
SSCVWASTFCSSSSTGLILLFSCGKIEIRSFPELSLVKDTTLKCFTCLPMKPNTLPDYFI
CSSADGEVIMMRSDQEVAVASMFLQNDKYRHLDSLSRVYDKHLTTLEDSSTSLSVHHKEK
KKGMFSNLFKDVTVSKTNHGADNEAADGKESYEELSNNLAVSNFPTQVEAPANSAPADRA
LETENVDMDIDDIDLDDQDEKPKGQNMIAMLNKQKLASRFNSFKGKLKQMTAKNEKPSTH
EEPQIEKTETQAVDQIKKKYGFSSSSTNTESNIAEQTKNKLMENVKKLQGISLKTTEMQD
NAQTFSSMAKETLRLAEQKNSPSKT
>Sgl40891 E3_adaptor/Cullin_RING/SCF/F-box 15.1 0.0
MEEELAMLRQLLSNFHELSQLYGYHTSSSFHPHLFSQSSSRCCILNLDDNLVEENYNSVI
MAAENPGILKMVDLYKPPPAKKSRKERSRGKQCRSSNSSENMSQELWKDFPDDLLEVVIA
RLPIASFFRFRSVCQKWNSLLASRSFLEHCSQVSQSQPWFYTITHENVNTGAIYDPSTKK
WRHPTIPSLPPKVILLPVASAGGLVCFLDLGHRYFYICNPLTQSWKELPERSVKVWSRVA
VGMIRYGNSAAGGAYKILWFGRDGEYEIYDSMKNSWARPGILPSNIKLPLSLNFRSHTVS
IESTIYFLRSDPEGIVSYDLESGIWKQYLIPTPPNSTDHNLAECGGQIFLVGLLTKNAAT
CVCIWELQKMTLLWKEVDRMPNVWCLEFYGKHVRMNCLGNKGLLLLSLRSRQMNRIVTYD
VAKRDWLKVPGCVLPHGRKRQFIACGTAFYPSLTAVP
>Sgl40932 E3_activity/RING/RING 11.5 9.4
MKRQLTLLTPFHSFIHLSLSIFISVKSFFFLFLSPNFGLSFLSLTNFNQQFTIVNFSPTQ
FLLHFRDFNNLKNCTEWLEMGEHLVLDVDRFVEHTSVQEQAEVASSSSSNSRLEGKKEED
VNEGEGGEDEPLIQMAECRICQEEDGISSLEVPCTCSGSLKYAHRKCVQRWCNEKGDITC
EICHQPYQPGYTAPPPAPQPEDASIDIGGGWTISGTPLDLHDPRLLAIAEAERQFLEAEY
DDYAASSASGAAFCRSAALILMALLLLRHAWTVPDSDDEDDMSAFFSLFLLRAAGFLLPC
YIMAWAISILQRRRQRQEAAALAATQVAFVLQSGQRRGLQFMIAPRSPSAVADEAV
>Sgl40953 E3_activity/RING/RING 33.8 5.5
MASESETEMQSMLERLISSRNRDLSTFLPLLFGIDPDPTHEVSGQNTGNPDHNTGNHSDP
DDQSQHQRDRIVLINPLTQGMVVIEGAGFDSLFRGLQSKDGQPPASKSAIEAMPSVEITE
DDQGQECVICLDGYEVGKSVKEMPCKHRFHGGCIEKWLKLHGSCPVCRFKMPIEEGGGGK
KSDENDDGDRMIGEREVWVSFTIGGSRRRRSSDENGNNTEDGNGNGSISGDLGNGSSEME
>Sgl40969 E3_activity/RING/RING 24 3.4
MGSHEPYWRTNTSFSPPPSRWDYGFQSEGIHYGSSESIQLFGSTSSNSKESRSWIRGGYH
PSHQYSASEGGAQYFSSPSDASLIQPWTPPPIRRISIDGFETSARRDTISGPLSFTPTME
GTSMVRDGGGFTSPHSDGSEFEHTAKLNLSTPRNFPSRRSFMSKPVHPLSFPVHSFTREA
SASPAAGFSAYDAATPQRDTHRLSSGSSSIDLTDISERLEPEFLARSSNVSEGFKCGLCD
RNLSQRSPWSSRRIVKSEDMPVAAVLSCRHVFHAECLDQATPKSHKSDPPCPICSKQEKE
HSPEQHIFPRLRNHLPRLRAFSEEGSSRTWSCVQAGDCVEGALHTPQKSSMLLLNRHKIK
KSLSHKGNSGKDFPGKLKKTSSNPLHLFGGKFLDHGAGGCSKTAAGPSNKKG
>Sgl41030 ULD/UDP/UFD/PB1 60.2 0.0
MSPPLLGVEGGGQSNDHPLVPSPTCTESGLKEHNYFGLSECSSVDSSNVSSLSEDNKGSL
NLKATELRLGLPGSQSPERDSDLCLVSASKLDEKPLFPLTPLKDGISSSSEKAAVSGSKR
GFSDTEHNWALKSSAHDTEAPKSVAQGKLPANDGVNVMLASRPGPPQAPPKSGAPQAPQK
ALGELPRPNSSNNAPAAKAQVVGWPPIRSFRKNTLATTSKNSEPLFVKVSMDGAPYLRKV
DLRTYTTYQELSSGLEKMFSCFTLGQCGSNMSETKLRDLLHGSEYVLTYEDKDGDWMLVG
DVPWEMFTESCKRLKIMKGSDAIGLAPRVMEKSKSRN
>Sgl41032 E3_activity/RING/RING 15.5 7.3
MGTGWRRAFCTSIPKNPDSTTTTTTNNTHNTTTSNRSPKLGFTKFNFFSSSSSAPSTPRS
QTPVSELKSPNLRCKTSIDETSPSTISPKLKYKKPNINTITTSSSAPSSPHSPSTFALLL
KNSLRLTKQTRCGVCLHSVKTGQGTAIFTAECSHTFHFPCITTLASKNNGVLLCCPLCGS
QWKEAPFLGTQNKIKIKSTSNNKSTLQSDLRLYDDDEPLAACAASIRFNPIPESEEENDN
GDDDDDNDEFPGFFADPVTPRHQITDANSRGVKVSISPEAAVIAVGRTYETYAVLLTVKA
PPFTARIRRPSVDVVVVLDVGSEMNDVKLHAMKRAMRGMICSLNSNDRLSMVVFSSHTKR
LLPLRRMTPSGKRSARRIIDAINLASEGCSLNDALRKAAKVVQDRKEKNQFASIVLLHGR
DEEKECGSVKTPCLGSSIRFSEIPVHTYKLRESFSDEEFVKSVNIFLSVVVLDVRVQFGL
ACGSAKAEIAAVYSCTGRPCLLNSGAAKLGDLYSSEEREIMVELRVPAASIGSHHMLSVR
SYHKDPSNSKQVIYGGDQSLIVPRPHTIRSSDPKIQRLRGLFVMTRAVAESRRLLGERND
LIGAERLLGSARAVLSQPGLRVTAADEYRRRVDAELAEVKWRRQGQSQGQTEEKRRREKE
GSIQGSGGNSGCCLVNEKGEPLTPTSAWKAAERLAKVAMMRKNLNRVSDLHGFEDARF
>Sgl41047 E3_adaptor/Cullin_RING/DCX/DWD 52.6 3.9
MSGNCLNFEEPIKDAITRLRFAPTSNNLLISSWDYSIRLVDVNTGKLRLEAQTEAAVLDC
CFEDEFAAFSAASDGSIFRYDLESGAYDIIGKHEDSATCVEYSPEISKLITGGWDGKVLS
WDMRSAKASQSVIYSNLHVESVSLCGIELLMTTGTSVRKYDLRKLNGAIQAEDLSMGFWI
RCVRSMACQKGFAVGSVDGHVTLQSDSDGMGYTFRCIPKSKKGKYHLVTVNDIAFSPSLP
GAFVTGDYEGYVIAWDGSSRKRLLELPRYPNSVASLSYNHTGELLAIASSYTYQEANERE
DNPQIFIQKLGESCLKSASYGSSSRR
>Sgl41079 E3_activity/RING/RING 15.5 7.3
MGTGWRRAFCTSIPKNPDSTTTTTNNNTHNTTTSNRSPKLGFTKFNFFSSSSSAPSTPRS
QTPVSELKSLNIRCKISIDETSSSTISPKLKYKNPNINTVTTSSSAPSSPHSPSTFALLL
KNSLRLTKQTRCGVCLHSVKTGQGTAIFTAECSHTFHFPCITTLASKNNGVLLCCPLCGS
QWKEAPFLGTQNKIKIKSTSNNKSTLQSDLRLYDDDEPLAACAASIRFNPIPESEEENDN
GDDDDDNDEFPGFFADPVTPRHQITDANSRGVKVSISPEAAVIAVGRTYETYAVLLTVKA
PPFTARIRRPSVDVVVVLDVGSEMNDVKLHAMKRAMRGMICSLNSNDRLSMVVFSSHTKR
LLPLRRMTPSGKRSARRIIDAINLASEGCSLNDALRKAAKVVQDRKEKSQFASIVLLHGR
DEEKECGSVKTPCLGSSIRFSEIPVHTYKLRESFSDEEFVKSVNIFLSVVVLDVRVQFGL
ACGSAKAEIAAVYSCTGRPCLLNSGAAKLGDLYSSEEREIMVELRVPAASIGSHHMLSVR
SYHKDPSNSKQVIYGGDQSLIVPRPHTIRSSDPKIQRLRGLFVMTRAVAESRRLLGERND
LIGAERLLGSARAVLSQPGLRVTAADEYRRRVDAELAEVKWRRQGQSQGQGQSEEKRRRE
KDGSVQGGGSGSNSGCCLVDEKGEPLTPTSAWKAAERLAKVAMMRKNLNRVSDLHGFEDA
RF
>Sgl41083 E3_adaptor/Cullin_RING/DCX/DWD 105.9 24.7
MKLLQCHFDDDSQSSNSNSFRSGYSSSSSSSSLTSQRSLQSVPSLSSPESQLDQKNNIFY
QCISTLKGHTSYVFSLVLHGKHLYSGSSNEEIRVWPREQTLTTHYQTQNNDNNNNNNNNV
VATSNGAVKSLVAWGDKLFSAHQDHKIRVWKIDNNNNSSNSNGNSNSNNSNSNNNSNSQK
SYQCVATLPTMNDRFSRLFSAKNYIKVRRHKSCTWVHHVDTVSSLALSADGSLLYSASWD
RSFKVWRTSDFKCLESVSNAHDDAINAITTSTDGFIYTGSADKTIKVWKKNHQTGATNHS
LVATLKRHKSAVNALALSKDGSVLYSGACDRSIVVWAKHNSLNQSESGGDDEDDHMVVVG
ALRGHTKAILCLTVVSDLLCSGSADNTIRVWKRTDDGGDKGYTCLAVLQGHTKPVKCITA
MVDPKCSSDSGTCYLIYSGSLDCDIKVWKIWVPFQ
>Sgl41241 E3_adaptor/Cullin_RING/SCF/F-box 12 0.0
MMQRLRDGDYMTMVDEEEEEDDDQGSPINRSGKRPKFTQKTRHLEHDDEDEEDDEDNEDE
IEKENMLYNSYYYIPPPSPTPSIVVCDALEFEFPIIYVNTTFEISTGYRANEVLGRNCRF
LQFRDPHAQRRHPLVDPVVVSEMRRCLEDGVEFQGELLNFRKDGTPLVNRLRLQPIYADD
GAVTHVIGIQLFSEAKINLNHVSYPVYKQTYDRRFKCTDEHSIKGGDLCGILQLSDEVLA
YNILSRLTPRDVASIGSVCRRIYQLTKNEHVRKMVCQNLWGREVTCNLELMTKNLGWVRL
ARELTTLEAVSWRKFTVGGSVEPSRCNFSACAAGNRLVLFGGEGVGMQPMDDTFVLNLDS
EHPEWRRVIVKSSPPGRWGHTLSCLNGSWLVVFGGCGRQGLLNDVFVLDLDAKQPTWTEI
SGGTPPVRRSWHSSCTVDGSKLVVSGGCTDYGVLLSDTYLLDLTTDRPVWTEIPTSWAPP
SRLGHSLSVYGRKKIFMFGGLVKSGQLRLRSGEAYTIDIGSEDPGWQQLDCGMGSQGGVV
PPPRLDHVAVSMPCGRIIIFGGSIAGLHSPSQIFLLDPSEEKPTWRTLNVPGQPPKFAWG
HSTCVVGGTRVLVLGGHTGEEWILNELHELCLASKHDSEL
>Sgl41298 E3_activity/RING/RING 12.4 0.1
MEFLELAKETQIEGKTRCPCNKCKLSKWLPVNDVGGHILFHGFYKIIENWIFHRVGEESN
IHQSLGEQSNVIGRDDMEGLLKSMFRANNPHSIHEPIEDPFDESDFREDGLHDIDVESGV
AHEDDDCDEFQYENTNEEAKFRRLMDASQEALYEGCSTFSKLSFLLHLFHLKCLYHWSAE
SFTKLLELLIDAFFQIKEFPSSY
>Sgl41391 E3_adaptor/Cullin_RING/Cullin 709.2 3.5
MVLHKFGEKLYLGLVGTMTAHLKEISKSVEIAQGGSFLEELNRKWTDHNKALQMIRDILM
YMDRTFVPSTHKTPVYELGLNLWRDNVIHSSNIQTRLLNTLLELIQKERTGEVINRGLMR
NIIKMLMDLGASVYQEDFEKPFLEVSANFYRVESQEFIECCDCGDYLKKAERRLNEEIER
VSHYLDLRSEFKITKVVEREMIANHMPRLVHMENSGLVNMLLDDKYEDLGRMYSLFRRVD
NGLGTIRDVMTSHIRETGKQLVTDPEKVKDPVEFVQRLLDEKDKYDKIISLAFTNDKTFQ
NALNSSFEYFINLNTRSPEFISLFVDDKLRKGLKGVSEEDVEIVLDKVMMLFRYLQEKDV
FEKYYKQHLAKRLLSGKTVSDDAERSLIVKLKTECGYQFTSKLEGMFTDMKTSQDTIQGF
YANHGAELGDGPTLVVQVLTTGSWPTQPSVPCNLPAELSLLCEKFRSYYLGTHTGRRLSW
QTNMGTADIKAIFSKGQKHELNVSTFQMCVLMLFNNADKLSYREIEQATEIPAPELKRCL
QSLACVKGKNVLRKEPMSKDIGENDVFLFNDKFTSKFYKVKIGTVVAQKESEPEKQETRQ
RVEEDRKPQIEAAIVRIMKSRKVLDHNNIIAEVTKQLQSRFLPNPVEIKKRIESLIEREF
LERDSADRKLYRYLA
>Sgl41570 E3_activity/RING/RING 14.7 11.9
MSTVVTRSPANQDRPLLLQPPRRSSDQRRIRTLLDLLTIEKTDGGDRTGRQSEEEINNNN
NNSSSNNISRWKVLRERLGLKVVGCCGIVTWGYDGNSNSSPLEEQNDVVQQGEEGEEEQS
MTRQQENEEGMNLAAALAAERQFRAVESSGGYGVDEDGGLLATPSRVSLMRLLEETSDGC
ELERDRSNGGGGGEERSESGSIGGGDGVCCVCMGRKKGAAFIPCGHTYCRVCSRELWLNR
GSCPLCNRRILEILDIF
>Sgl41576 E3_adaptor/Cullin_RING/DCX/DWD 84 4.4
MVETSIAEGAIVPYLKPDSDSPHSTDDLNTNNNNNNNNNNNDNDESISCDNDFLCPICMQ
IIKDAFLTACGHSYCFMCISTHLRNKSDCPCCGRFLTPKLIFPNITLDKILKKMSNHQFT
ESASSTEQLRRALVQGCNVSVKDLNCLLSLLAEKKRKMEQEEAETNLQVLFEFLICLRKR
KLEELSQIQNDLQYIEEDIDAVQKRKTDLLNETKSHLRLGVRGDDADTNGICSIVPTPVR
GGGSVAQQTRFSENQHSGRDNEVVPCSREFIENVDHTSLGLQQLAPDEGFKTRKRQVEAQ
FTDLQECYLQKRRLGAKQNQATETRDLNNMNSLGYHAGLVDFQSVLTSCTRYSQLRVMSE
LRLGNVFHSANIISSIEFDRDHELFATAGVSKRIKVFEFSSVVDEPEEVHCAVVDIPTRS
KLSCLSWNKYTKHCIASSDYEGIVTVWDVATNQSVGEYEEHEKRAWSVDFSRTEPSLLVS
GGDDCKVKIWCTKQERSVLNIDMNANICSVKCNPGSSMHVAVGSADHNIHYYDLRNISQP
LHVFSGHRKAVSYVKFLSTHELASASTDSTLRLWDVKENKLLQTYRGHINEKNFVGLTSN
SEYLSCGSETNEVFVYHKAISKPVARYKFNRSELYDADVERGSHFISAVCWKSDSQVIMA
ANSQGNVKLLALTA
>Sgl41601 E3_activity/RING/PHD 36.7 7.1
MAKTRPGKRDLDSYSIKGTNKVVRVGDCVLMRPADVGKPPYVARVEKIEADSRNNVKVRV
RWYYRPEESMGGRRQFHGAKELFLSDHHDVQSAHTIEGKCIVHSFKNYTKLENVGADDYF
CRFEYKAATGAFTPDRVAVYCKCEMPYNPDDLMVQCEGCKDWFHPSCMGMTIEEAKKLDH
FLCSDCVAEDDPKKGDSTFSASPLADGKPDNKRRKR
>Sgl41603 ULD/UDP/UFD/UBX 49.9 0.0
MASKDKKTSRSVSGGSRPAGGIRTLADLNRRSTPDSDSDSDNAPQEYYTGGEKSGMLVQE
PSKGNDVDDIFSQARQLGAVEGPMENLLPSSSRSFTGTGRTLASGDAVASATSPPESVVH
NIVFWQNGFTVNDGPLRRLDDPENATFLESIRKSECPKELEPEDRRSQVHVNLIRRETNC
PEPEVRTVPFQGVGRTLGGSTSAAVSDQTPAAPLNSAPPPSAGLVVDENQPSTSIQLRLA
DGTRMVARFNFHHTVNDIRTFIDSSRPGGSRTYQLQTVGFPPKPLSDLDQTIEQAGLANS
VVIQKL
>Sgl41616 E3_adaptor/Cullin_RING/DCX/DWD 82.8 4.9
MVETSIAEGAIVPYLKPDSDSPHSTDDLNTNNNNNNNNNNNDNDESISCDNDFLCPICMQ
IIKDAFLTACGHSYCFMCISTHLRNKSDCPCCGRFLTPKLIFPNITLDKKPMCHPVLEFY
VCTQLLGTKSEFNLHLPYGDTIGTQLSPCLQLIKILKKMSNHQFTESASSTEQLRRALVQ
GCNVSVKDLNCLLSLLAEKKRKMEQEEAETNLQVLFEFLICLRKRKLEELSQIQNDLQYI
DEDIDAVQKRKTDLLNETKSHLRLGVRGDDADTNGICSIVPTPVRGGGSVAQQARFSENQ
HSGRDNEVVPCSREFIENVDHTSLGLQQLAPDEGFKTRKRQVEAQFTDLQECYLQKRRLG
AKQKQATETRDLNNMNSLGYHAGLVDFQSVLTSCTRYSQLRVMSELRLGNVFHSANIISS
IEFDRDHELFATAGVSKRIKVFEFSSVVDEPEEVHCAVVDIPTRSKLSCLSWNKYTKHCI
ASSDYEGIVTVWDVATNQSVGEYEEHEKRAWSVDFSRTEPSLLVSGGDDCKVKIWCTKQE
RSVLNIDMNANICSVKCNPGSSMHVAVGSADHNIHYYDLRNISQPLHVFSGHRKAVSYVK
FLSTHELASASTDSTLRLWDVKENKLLQTYRGHINEKNFVGLTSNSEYLSCGSETNEVFV
YHKAISKPVARYKFNRSELYDADVERGSHFISAVCWKSDSQVIMAANSQGNVKLLALTA
>Sgl41702 DUB/USP 140.5 0.7
MGSKRDREEQTDGEVKRQKVEEEKESDSPKMHAFENPLLPLASYDDDEEEEERRREAIRR
RGVEENAKNAELNGRVNEVYDDDDDEEDEDDANFNQGKRNRSVEVRRDCPYLDTVNRQVL
DFDFEKFCSISLTNLNVYACLVCGKYFQGRGPKSHAYTHSLEAGHHVYINLKTEKVYCLP
DGYEINDPSLDDIRHVLNPRFNREQVQQLDKSKLWARALDGSDYLPGLVGLNNIKETEFV
NVTIQALMRVTPLRNFFLIPENYQHCKSPLVHRFGELTRKIWHARNFKGQVSPHEFLQAV
MKASKKRFRIGAQSDPVEFVSWLLNTLHTDLRSSKKNTSIIYDCFQGELEVEKEIQSKGV
VDRRENGDDQNGGSENPNVVRETFKMPFLMLGLDLPPPPLFQDVMEKNIIPQVPLFNILK
KFDGETITEVVRPQLARMKYRVTKLPPYIILHMRRFTKNNFFVEKNPTLVNFPVKNLELK
DYIPLPPQKEVKKSRTKYDLIANIVHEGKPNEGTYRVFVQRKSEEQWYEVQDLHVSETLP
QMVALSEAYMQVYELQQQP
>Sgl41705 E3_activity/RING/RING 32 9.9
MEYVDDDDDDDDDGGSEDEGDDMNKATTSEECKDVHVDNLDDDDEDDCVCVEEQNEECFD
DVIDCVKYWKKTQDGEEEPIIVFEMKPLLTIQEMELELMEDGNYKLLIDTTNTKLVGDEC
SICISGLTESVPKSSIFPWFPRMNSWCIVKLDCGHVFHHHCIFKWLARTPSCPLCRSSSI
VTV
>Sgl41711 ULD/UDP/UBQ/UBQ_Other 42 0.2
MSPVGGTASYRRPSKRKLEELCDACNSLPIRRNSISNFAGNSVIDSRFQSIPAGNSECKH
VNSDSTTFEIQFFVRMLSGETLVMRANLEDTVETVHRRISERKKIGVDVQRLLYNGKQLQ
LQETLKNSKIKNDAMLHLVGRMQSTDYPKVWRILCDLNSIIGRICKKELPFADPSPVKYT
MQQFMALRLDQDISLMVAFGRQFYHEKRRKLVQSGGIINKYDFCQIFMDACAPQSLIALY
MLGNKIYKECAEECIKSFVDFVKAFEGTWIERAYCAKPVLEFCKSLRMMVKEDDHLYIHC
RSVLGSMLAKVEVIKWPEDVSDVHDYVHDYVVGTDVFPFVKELGQTLLKDLVQSVESDSD
GPLYRDVCDFSALLQPVLSLIGMQPPAAANSLRTEGNYKLVTDVRDHIRLIFTNFLSWVD
KGLHKVKLSLFMKKKKGVVASTGGWSQYLAILKILHSISHFYPGSQDIFWTIVRLHKTGV
CSLILNYAERANDNSWLLQQRDILDFDSRRHLSLLLFPEVKEDYGDMLEMLIDRSNLLAE
SFEYMRDASSSSLHAGIFMQFKEEVATGPGVLREWFCLVCQAIFDSRHALFVSCPSDRRR
FYPSPGKSFVVCASKVQPQYLEYFKFSGRVVALALMYKIQVGVVLDRVFFLQLAGRHVSV
EDIRVADPFLYGSCKQILEMEAAFVDSDVLGLTFVTEEEELGARKVVELCDGGKDIAVNS
KNRKIFVDLIIKHRFVTSIAEQVSYFASGFSDIIGGDDLKKTFFEILELEDLDWMLHGSE
SEICVKDWMSHTEYTGFRKTDPQIIWFWEVVETLSAQQKKMLLFFWTSLKYLPVEGFRGL
ASQLYICNSKESEEFFPSSHTCFYQLCIPPYPSKDVMQQRLLVITQEHVSSSFGSE
>Sgl41712 E3_adaptor/Cullin_RING/SCF/F-box 15.2 0.0
MTELMDLPIDLTINIFLRLNAKPLMQFKSVCKLWYYLISSPRFEELHLDQTLAQSNPKLQ
FVFSAPYLSSAEFDTFDRICELDNPFRIQGFAHVVGSCHGLLCLTNYDLHLTIVLYNPTT
RTHKRLPFLPKPSSLSHRYSFGFGYDGVSRDYKFVRILQSDEGMGPFKSQVMVYSSKMDS
WVRAPDVPCPYFSYREDGVFVNGTLHWIHESLLKDVKFFRIVGFNLGNHSFIEVPQPQFE
EKFINLRVGVLDGCLCLVVNDLDYSEIWIMKEYGVVESWTRLYKVKQSQRLMFLEWPIAY
SLNQQKLFLQLNTWRVVSLDLQTMVLNDIKVCDFPRCFDTRVCIENLTMLKDTGSEVLEI
DHQQEKKRRRRGKDMHQRRTISVDDILDEHMEE
>Sgl41778 E3_adaptor/Cullin_RING/DCX/DWD 58.1 12.1
MDVTNWDEDAYRNTILEERGLEYRTVFRAIFGPSSTSNPNSDIVVSASSDGSIAAYSVST
ILSSHELCNGISNSQKVPAVQPNCFLQAHQGPAYDVKFYGDDADALLLSCGDDGRIKGWK
WKELEFSDTTIHVQGSHVKPIIDLINPQHRGPWNAMSPISENNAIAVDHQGGSIFAAAGD
TCAYNWDVETSKIKMVFKGHSDYLHCIIACKGSNQIITGSEDGTARIWDCRSGKCVQMIS
PERSKGLKELSSVSCITLDASESWLAYGSGQSIFVWNLLASQQISRICTPTTCQDVVFDH
NNILAVGSSPILARMDINGKILSQIRCAPESAFSVSLNRSGVVAVAGYGGLVDVISEFGS
HMCTFRSTSTRAEQAS
>Sgl41783 E3_adaptor/Cullin_RING/BCR/BTB 35.1 1.0
MQALSRPLFLLSVATSLSNRLTENEDSSGSSDASQPRIDPQSETLVTIASDSRGIDDTYR
LSKCVQIARLYLEGNNIETLARLLRLRRKTMQIAIQQYHTRSAAAWNYIPTTIFNHLLRF
KSDHSPILLLCHLTSTKEKRKRKGFKFESCWLLDETCEQVVRDAWSMGCDVGSKIEDVAR
GLRIWSGTKYNALGKKIKEVEESLRIAQNSPISEESCKECQQLESTLEDLNEKGNTGSRA
VTIMESRTAFSDSNDISNGSSICCIPNNTGTVTGTGTTTPTPDTADTAALCRLSENIQSL
FHPESESESFSDAKIVVSGDCREVSVHRCILSARSPFFRAEFSSRRKDKDKDKDNHKVEL
ELKDLAGDIDVRYESLVAVLGYLYSGKHTSNNLPHSVRVCVDDDCTHLACRPALDFALQV
LYLSHKFEILELLALYQRHLMEMLDKAAPDDILIVLSVADMCGSACERLRGRCIDLAVRS
NVDVTSLDKTLPQDIVKQIIDSRKEIGLTDPGYVEFPDKHVKRIHRALESDDVELVRMLL
KERHTTLDDAYALHYAVAHCDAKTTAELLELGLADVNLRNLRGYSVLHVAAMRKEPKIIV
SLLTKGAHPADITSDGKKALQIAKRLTKAVDFYKPTEQGKASPKDRLCIEILEQAERREP
LLGEGSVSLAKAGDDLRMKLLYLENRVALARLLFPMEAKVAMDIAQVDGTSEFTLSKNMA
DARRNAVDLNEAPFILKEEHLQRMKALSKTVELGKRFFPRCSDVLNKIMDAEDLSQLAFL
GNDTPEERQRKRKRYLELQDALTKAFSEDKEEFDRSTLSSSSSSTPLGRPYGKTNFRR
>Sgl41805 E3_adaptor/Cullin_RING/DCX/DWD 91.5 14.5
MRGKNQQSAVDEKYAQWKSLVPVLYDWLANHNLVWPSLSCRWGPQLEQATYKNRQRLYLS
EQTDGSVPNTLVIANCEIVKPRVAAAEHISQFNEEARSPFVKKYKTIIHPGEVNRIRELA
QHNHIVATHTDSPDVLIWDVETQPNRHAVLGASPSRPDLVLTGHKENAEFALAMCPKEPY
VLSGGKDRSVVLWSIQDHITTTASDPSSNKPQGSGATIAKPNGESPSVGPRGIFEGHEDT
VEDVQFCPKSSQEFCSVGDDSCLILWDARAGSDPAIKVEKAHNADLHCVDWNPFDENYIL
TGSADSSVHMFDRRKLTSDGVGSPVNKFEGHKAAVLCVQWSPDNPTVFGSAAEDGVLNIW
DYEKVGKKKEHDVTAPNGPPGLFFQHAGHRDKVVDFHWNAYDAWTIVSVSDDCDSSGGGG
TLQIWRMSDLIYRPEEEVLAELEEFKSHVATCGSKSEVRVIYYYNLVLLKILLFLLLPSI
RFFVLFIRFTFSCRYLRFFNSMLQQQAVLCSLQPSIKNVPFFSSQIPTSSSSLGLSMDYN
KFVSSSSFKSDYCNKLPFVSCKASIDAHNSSIKNENMPLPVHGVSEKVVGVLGGGQLGQM
LCQAASEMALKVAILDPKENCPASSLAHYHMVGSFDDSATVEEFAKRCGVLTVEIEHVDV
ATLEKLEQQGVDCQPKASTIRIIQDKYLQKLHFSQHGIPLPEFMQIDNFESAKRAGELFG
YPLMVKSKRLAYDGRGNAVAKSEEDLSSAITALGGYERDLYVEKWAPFVKELAVIVARGR
DNSILCYPVVETIHRENICHIVKAPAAVPWKIRKLATDVAHKAVSSLEGAGVFAVELFLT
EAGEILLNEVAPRPHNSGHHTIEACYTSQFEQHLRAVVGLPLGDPSMKTPAAIMYNILGE
EEGETGFLLAHDLMRRALTVPGASVHWYDKSEMKRQRKMGHITIVGSSMGIVDGHLKSLL
KEEKPADAIAPRVGIIMGSDSDLPVMKEASRILNMFEVAHEVRIVSAHRTPDVMFSYAKS
AWERGIQVIIAGAGGAAHLPGMVAALTALPVIGVPVRGSSMDGLDSLLSIVQMPRGVPVA
TVAINNATNAGLLAVRMLGVADSDLTSRMTQYLEDARDDVVVKADRLHKDGWEAYLNN
>Sgl41851 E3_activity/RING/RING 31.1 6.3
MGSSSSNLGSTSSPPPKHTKVNRTKQRLASFICGASASSTSEREDYAAGSVLNSADYSQQ
KANKSSSTINNSCSTSSMGTGFSSYSSPRSGAVSSSDSSNISSEFTSIQDSRVESSGKRK
CSSEVEEVVLPCTVNAERKHHQRRLADSVSTSSTGQSQHRGLSSNAHTDDLNNDMLQINS
EILSPTSLQHQEPEQPTVLEEVTEITGSQNSDSVVLPDVSESGLASQSRGDEAIREAMPS
GLELFVSDRTEARSGSEESLLHVDLVSISSNLLPNINNETSTREARRNSRRMFRDAFSSR
SSRRNADFPAILFATEDSSLMGSHRRWLLDLGDDFFDDSVDAEPWRFGRRSRFTNDRRRN
SRSEFWDRLRGAATENPHRTSCPLDLHPRGSCTCEVDEEASALSSISRIILLAEALFEVL
DEIHRQPDSFSLSMLSVPAPESVVDSLPIKTYEKPSTADHADDADQCYICLVEYEKGDKI
RVLPCQHAYHMSCVDKWLKEIHGICPLCRGDVRGGATEVAASSSDSVLT
>Sgl41853 E3_activity/RING/RING 28.4 11.2
MAAGKLPGVEAARRRRIHQSSSGSSFSSSSGTIIGSSPCSRRSSYSLFTPNSSSASSLLE
PRIRTYQDYDDEKLGHLARQAKERLDEKLRAQTKSLIRRKNSDLSEDGTSRRSEMNGRDL
RTEVYGSKKNGGAKKLMGWGKLGWKSGEQQECAVCLDEFRVGENLVNLPCAHRFHSRCLV
PWLNNHAQCPCCRMSIFSNP
>Sgl41854 E3_activity/RING/RING 29.8 9.9
MAGMLPGVEAARRRRVHQSNGSSTSSSSGIAIGSSPCSRRSSFSLFYPNSSASSLSQPRS
RTYQDDEKLGHLARQAKERLDEKLRAQTKSFMRRNNSDLSENGTIQRSEMSGRDLRTEVY
GSKKNGGAKKLMGWAKLGWKSGEQQECAVCLDEFRVGENLVNLPCAHRFHSRCLVPWLNN
NAQCPCCRMSIFSDP
>Sgl41866 ULD/UDP/UBQ/UBQ_PIM 73.9 0.2
MAHSANEVAGSNEAGNSGTSIEIKIKTMDSQTYTMQVDKQMPVPALKDRIASVTGVVTEH
QRLICRGKVLKDDQLLSAYHVEDGHTLHLVVREPNASSSGSLPADPAVDRSSNGNRGQYY
QVAPGIVVETFNMPGQGDRVLPDVSRIVSAVLGSIGITNPGNNNETTGTRDHAADRPGES
PILDGMADASRTQPEQSGMRSSNDRSRLHNAFGIPAGLSFGSLQAPVVPDALATLSQYLG
NMRQDFTDSGRTSGTDSGASLHGNGGSSTLAQSGSGPEGLPSPASLAALLSATRQMLGQQ
VEEFLLQLGRQLENQENITDPVARVTAQSGALRNGSLLHNLGAYFLELGRTVTTLRFGGS
PAEAVVNTGPAVFISPSGPNPLMVQPVPFQPGASFGTPLSGTLPSNSGTINSNGGGIVPR
RIDIQIRRVGPSAHQAEPVGSQQSSGQRNPTTNVSGEEQVNQSSNGTTGVPSSNNGPTVR
ILPLRSMMAAVPDLNRPPQESSGNSVGLLYPVVGRYSSIPSGNLSNRTGNQVSNEHPSSG
QPQSSPESTVQHNVEGAAGNGRVPASNPGQRESVSSRTIDINILSAGGVQNDQNTEGQIP
PGILQILRGLFPGGEFHVESVSSQGTGSGSAMEQERSSSAVAQEAEPTATEEGLFLSRVL
QQLMPLISLNSGTEQSGGYSGGASQQGDGLASSTVVEDHQAGTSRRDDDENPGPNPKRQR
RE
>Sgl41887 UBD/Alpha-Helix/UBA 49.2 1.4
MAAKLKIAGIWVGVLEIELKDYTVRMLREEIAKRSNCDAITVNLICGGRVLKDSDNELTD
VGVKNNAKIMATRINFAEGRTLQRELMAQEHRSSKLDRLKATVDRLAQRHADGSLPVEDY
NIELEDQNGQRVNMGCETDQKSIMMGLMLHSKGKKLVRKQLYKDALEVFELGEEAFSLCD
PKLIERVDNVSILQIDMVWCYFMLRDINLLSVAGERLAKAREGIERAHGKDASRVRLLQG
SHSIEVALYLRMELLEGVVAFHCGKLEKSREALTSAKMRFSKLEVKDETLSLLLSMGYDV
DEAKKALKMNGQDVQSAINFLVEENLKKIRKMEEDLQRQQEIREQKMYGKTPLGKAVDLQ
MLKGLSSIGFERELAAEALRRHENDTQKALDDLTNPELNSNIQLDIESKKRKRQQKHVNT
IIEELVSMGFERSRVTAAVDSHGTKAEALNVLLAQSAQPPPAAVDGILSSDSTPGSSNSP
NEDEGEEDEGPFAILDGQLGKVQEFELEHELVEELDRGNAYSDYDIDVCKEGEAINEYLA
LLDSAMNGGN
>Sgl41921 E3_activity/RING/RING 30.6 3.4
MGKRKRTGASTADYLPSSPSDSMPCSSGRALMLGEQNSSDPGDVSIFKNHPSGREIMDSL
GKQPNSQLSLNKHQQNLSRSMFLKRSRHHFGNQYARRNSSNYHKPSASYGISPFQDERLC
FKLGSRYSSDMGHHPDFSEFRERAFWRPERIRSSSSVIHAVSADGARMGCGTCQKSLRRK
PHQLGSNPSPEELSIVAVLVCGHLFHADCLEQTTQLEDRRDPPCPVCSGFVPKAEPT
>Sgl41930 DUB/USP 268.4 0.6
MSRIKNISVPKPCPHLAEFKSKHGSNSFRDLQNLIRARPMGRASIYRAENEPSYCPSCSS
RPHRRLYACITCAGVSCYVHARLHPHPIAVDVDRAELFCWHCGDQVYDPDFDAAVLAAAA
PNLGEFVSLPPPLPLPCKRQKVEYCPREPAPTLEAVIVENSTSITQAGPGPGIDQGQGLM
LGPSLGLRGLNNLGSTCFMNCVLQALVHTPPLINYFLSDRHNRHFCLKRRNGGNGIGSGN
GNGNGKTRGRRGNGNEGKKMNLCLACDLDALFWAVFSGDRRPFSPAKLLYSWWQHAANLA
TYEQQDAHEFFISMLDGIHEKVKDQSKMQSQGNGDCCIAHKVFSGILRSDVMCMVCGFTS
TTYDPCVDISLDLEPNLFPKVGAQKSQKSCNEEADTMNFSFNNRTSTLTGCLDRFTRPER
LGPDQKFFCQQCQISQESLKQMSIRKLPLVTCFHIKRFEHSSSQNTARKLDRYVQFPFSL
DMAPFTSSSILRSRFGNRICSFVEEESQDVPDELSSEFELFAVITHTGKLNGGHYVAYLR
LSNQWYKCDDAWITQVSENIVRAAQGYMMFYVQKTFYYKASQTQMPS
>Sgl41952 E3_adaptor/Cullin_RING/DCX/DWD 97.5 24.7
MPAQKIETGHNDVVHDVQMDYYGKRVATASSDTTVKIIGMSSGSSTQPLATLTGHQGPVW
QVSWAHPKFGSILASCSYDGRVIIWKEGNQNEWAQAHVLQEHKSSVNSISWAPHELGLCL
ACGSSDGCISVLTARSDGGWDTNRIDQAHPVGVTSVSWAPATAPGALVGSGLLEPVNKLV
SGGCDNTVRVWKLENGTWRMDCFPALQMHSDWVRDVAWAPNLGLPKSTIASASQDGTVVI
WTVGKEGEQWEGKVLKDFKTPVWRVSWSLTGNLLAVADGNNNVTLWKEAVDGDWHQVSTV
EP
>Sgl41993 E3_adaptor/Cullin_RING/DCX/DWD 87.7 5.3
MRYFEELVTGGEWDEAEKYLSGFTKVDDNRYSMKIFFEIRKQKYLEALDKRDRAKAVEIL
VKDLKVFSAFNEELFKEITFLITLENFRENEQLSKYGDTKSARSIMLAELKKLIEANPLF
RDKLQFPTLRNSRLRTLINQSLNWQHQLCKTPKPNPDIKTLFVDHTCGPPNGPNGARAPS
PVTNTLMNASPVPKAGAFPPLGAHGPFQSAPAPLPTSLGGWMANPSPVPHPAVSAGPMGL
GVPNNPAAIVKRPRTPPNNNAAMDYQTADSEHVMKRSRPFGAPEEVNNLPVNILPVAYNS
QSHGQSSYSSLDLPRDVVMSLSQGSAVKSLDFHPSQQILLLVGTNMGEVMVWDLVSRERT
AYKNFKVWELNACSMPLQASLASDYSASINRVIWSPDGSLFGVAYSKHIVHIYAYHGPND
LRNHLEIEAHIGSVNDLAFSYPGKNLSIVTCGDDRLIKVWDAVTGAKQYTFEGHESPVYS
VCPHHKENIQFIFSTATDGKIKAWLYDNVGSRVDYDAPGHSSTRMSYSADGSRLFSCGTN
KEGESFLVEWNESEGTVKRTYLSLGKRSVGVVHFDNTKNRFLAAGDEFTIKFWDMDSVNL
LTTTDAGGGLPASPCIRFNKEGTLMAVSTSDNGVKVLANTDGVRLLRSVENRPFDTSSSA
SGAIVKGPTMGVFPAANAAVGASMGDRTAAVPAMVAMNADNRSLVDVKPKFPDESADKSK
IWKMTEINESSQCRSLRLPDSISAMRVSRLIYTNSGLAILALASNAVHKLWKWPRNDRNM
TGKSTASIAPQLWQPSSGILMTNDLSETAPEDAVSCFALSKNDSYVMSASGGKISLFNMM
TFKTMTTFMPAPPAATFLAFHPQDNNIIAIGMEDSSIQIYNVRVDEVKTKLKGHQKRITG
LAFSNVQNVLVSSGADSQLCVWSMDGWDKLASKSLQIPSGRSVNPLADTRVQFHQDQTHL
LAVHETQIAIFEATKLDCQKQWVAPEARGPITHATYSCDSQSIYVSFEDGSVSILTASNL
RLRCRINPNAYLSPNPSMRVYPVCIAAHPSEANQFALGLTDGGVCVLEPLESEGQWGTPP
PAENGAGTSNTVAGTDQPQR
>Sgl41994 UBD/ZnF/ZnF_UBP 93.1 8.3
MFTIRIHSVDINHPLFLSPPSNSNPIPNPNFIERRGIIHLFRNLDSHPSTSDSSSTTIQS
DLLFIVAVPNYFSSDDLLRFFGSYITDVSEFLIIRNDGMEDRYSVLIRTWSQDLADGFYR
RFNGMQLKYATXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLSVLSMEFTELAEIA
STPPSGYAELPTCPICLERLDQDTGGIQSTLCDHSFQCSCISKWTYLSCQVCRLCQQQDD
RPNCSVCDASENLWVCIVCGFVGCGRYKEGHTFRHWKDTRHCYSLSLETQRVWDYEGDNY
VHRLNHSKADGKSAMVDSHCMSHDGDCGTCGHSEDSEMAGALYSSKVEAITDEYNHLLAT
QLENQRQYYESLLVEAKSKKEYTIAEAVEKGVTTKMQDLQCRLEKYEEDKKAVLDMNRIL
MKSQEEYKKRMKEIEEREMKSLGSRDEQILDLEEQIRDLKIYVEAQRKIGSITGSDNMKG
GTLLPVPQTQSSPASAKRRTKTGRHRN
>Sgl41998 E3_adaptor/Cullin_RING/DCX/DWD 15.3 10.7
MSSSSIESKPWESMLPGPAGRNNGGASDMTSSGLLAFASGSSISLIDSRSMQLLSVLPLP
PPPSTSSYSTSLSLSPFVTSVRWAPHSLRHVDILSSDSHSLSSSHLLLAVGDRQGRLALL
DFKSRSPLLWFDSSHNQPPSLKLGIQDICWVKSSIDSWALAAITGPHMLSLYSTSTGRCF
FKYDAVSEFLSCIRRDPFDSRHFVVLGLKGFLLSVKVTADTEDDVVLQEFQIRTDSSELA
KLEKDLNGGGGGSGGGSHHGGSGSSSNNSSNTSPASAIFPNYIAKCAFSPEWQHILFVSF
PRELVVFDLHYETALFSANLPRGGRFLDVLPDPNSELLYSVHLDGKLTTWRRREGEQAYS
ICSTQELMPSVGSCVPSPSILAAVLCESDYALQNVGKIYSDVPHTPFSDEDFDNPFDFCD
ESLPASKTHLVSISDDGKVWNWLLTADGPEVVPKDVPKTKALVNDSGSRTSDANAGNDTN
EGSERFRGRERSSKLTVVPEDTSFKIILVGQLHLLSSTVTTLAVPSPSLTATLARGGNHP
AVAVPMVALGTQSGAIEIVDVSANAVTSSFSVHHGVVRGLRWLGNSRLVSFSYTQANEKS
GGYINRLVVTCVRSGFNRAFRVLQKPERAPIRALRASSSGRYLLLLFRDAPVEVWAMTKN
PIMLRSLALPFTVLEWTLPTVPRPSASTKQSSASLKDRIVGTQAGTSPQANDAPQEPKPV
SSEGSQDESSESFSFALVNGALGVFEVQGRRIKDFRPKWPSSSFVSSDGLITAMAYRLPH
VVMGDRSGNIRWWDVTTGQSSSFNTHREGIRRIKFSPVVSGDRSRGRVAVLFYDNTFAVY
DLDSPDPLANSVVQPQFPGTLVLELDWLHLRSHNDDPLVLCIAGADSSFRLVEVNVTDQR
PAHGAIREKFRPMPLCAPILLPTPHALALRMILQLGVKPSWFNTSSIMINKRPHHIPGTP
KSEADLRSYIIDTPPVGDVAVPEMLLKVLEPYRQEGSILDDERARLYAKILNKGSAVRFA
FASMIFGESSEALFWLQLPRALNHLIKKSLIKQPQKKATLEPVSQVDEVALLTEIKSSGK
LLPGSDRRESLSQGQLRLMAFEQEELWETANERILWHEKLNGEEAIQNQVHDLVSVGNLE
GAVSLLLSTSPESHYFHANALRAVALASAVSKSLLELAVKVVAANMVRTDKSLSGTHLLC
AVGRHQEACSQLQDAGCWTDAATLAATHLKGSDYSRVLQRWADHVLHTEHNLWRALILYV
AAGAFREALTALREAQQPDTAAMFVVACREIHADILANMEDAGQGVESSTKDQLLVLPEL
SLENEEVIAAYEVYGQYQRKLVHLCMDSLPFSEQ
>Sgl42009 E3_adaptor/Cullin_RING/DCX/DWD 19.9 0.4
MGQANSREGLELSDSDDYDERDSDKEEDYDTSEENQLHSTPPSSSSLDDVESRLKALKLK
YSTPAPASATASASSLRRKNAVKLYCHVGGNTSDSKWKTADASTSYSFVKSKESEDEDED
DEEDEDDEENMDGCFWQLRVGSKIRARVSSDLQLKMFPDQLRVDFVWNGVWALKFFEKNN
YYDMFLSEFQDCLFENVFGLKASDENKLKVYGKDFMGWHNPEAADDTMWDAVDEEAEVKT
PASSSRIKQDLLEEFEEEATGIQSMALGALDNSFLVGKDGIQVVKNFRHGIHGKGVTVKF
DRGSGNSSSYSTPKKAILMRGETNMMLMSPVLEDKPHAQGLHQLDIETGKVVTEWKFAKD
GADISMRDITTDNKGSQLDPSGSTFLGLDDNRLCQWDMRDRRGLVQEIASANSPVLHWTQ
GHQFSRGTNFQCFASTGDGSIVVGSLDGKIRLYSKTSMRQAKTAFPGLGSPITNVDVTYD
GKWVLGTTDTYLVLICTLFTDKDGRTKTGFGGRMGNRVSAPRLLKLTPVDAHMAGPAPNN
KFHSGQFSWVTEEGKQERHIVVTAGKFSVIWNFEQVKNSAHECYRNQQGLKSCYCYKIVL
KDESIVDSRFMHEKFAVSDSPEAPLVVATPMKVTSFSISNKQ
>Sgl42021 DUB/USP 268.4 0.7
MSRIKNISVPKPCPHLAEFKSKHGSNSFRDLQNLIRARPMGRASIYRAENEPSYCPSCSS
RPHRRLYACITCAGVSCYVHARLHPHPIAVDVDRAELFCWHCGDQVYDPDFDAAVLAAAA
PNLGEFVSLPPPLPLPCKRQKVEYCPREPAPTLEAVIVENSTSITQAGPGPGIDQGQGLM
LGPSLGLRGLNNLGSTCFMNCVLQALVHTPPLINYFLSDRHNRHFCLKRRNGGNGIGSGN
GNGKTRGRRGNGNEGKKMNLCLACDLDALFWAVFSGDRRPFSPAKLLYSWWQHAANLATY
EQQDAHEFFISMLDGIHEKVKDQSKMQSQGNGDCCIAHKVFSGILRSDVMCMVCGFTSTT
YDPCVDISLDLEPNLFPKVGAQKSQKSCNEEADTMNFSFNNRTSTLTGCLDRFTRPERLG
PDQKFFCQQCQISQESLKQMSIRKLPLVTCFHIKRFEHSSSQNTARKLDRYVQFPFSLDM
APFTSSSILRSRFGNRICSFVEEESQDVPDELSSEFELFAVITHTGKLNGGHYVAYLRLS
NQWYKCDDAWITQVSENIVRAAQGYMMFYVQKTFYYKASQTQMPS
>Sgl42031 E3_adaptor/Cullin_RING/SCF/F-box 20 0.0
MPTLVNYSGKDELSMGLVDAYGPPFKRARITAPFVLWGHESEQEKRSSISVLPDECLFEI
FRRLPGQERSNCAGVSKHWLTLLTSIRRTEMWDKDTVVMSDDKEVDGCLTRSVEGKKATD
VRLAAIAVGTAARGGLGKLSIRASSGVTNSGLSAVARGCPSLKSLSLWNVPSIGDEGLFE
IANECHLLEKLDLCHCPSITNKGVSAIAEKCPNLTTISIESCHNLGNDSIQAIAQGCPKL
ESISIKDCPLVGDQGLASLFSSSSSVLTKAKLQSLNISDFSLAVIGHYGKSLTSLTLSSL
KNVSEKGFWVMGNAQGLKALSCLSISSCLGVTDLSLEAIGKGCSSLKQISLRNCCFMSNN
GLVGFSKSAESLETMQLEDCNRITLIGVVSALSNCSSRFRSLSLVKCMGLKDMPFQDAAL
VNPCISLRCLSIKNCPAVSSLSLSILGKMCPNLRQVDLSGLYGVTDEGVLSLLESSLAGL
VKLNLSGCIKLSDESVVAIAKLHGETIKVLNLEGCRKITDVSLSTISSSCPVLSELDVSN
SAVTDSGVAALSCSELNLQILSISGCSKISNKSLPYLIQLGKSLVGLNLQFCNSLSSSIV
DMLMGNLWRCDILC
>Sgl42088 E3_activity/RING/RING 9.5 7.8
MPKTRRDRSVSFERSRKSPAPCSSSLSCESKAKDSPPTGEDLKEWEDARCPVCMEHPHNA
VLLICSAYDKGCRPYMCDTSYRHSNCLDQFRKSFAEASTEAEMEEDVQPPPVQSSEIVAI
ETVVTSHDEGKSEDSVAADIASMHKLQQKLVCPLCRGQVIGWVVAESARDFMNEKTRSCS
CETCEFTGNYTDLRKHARLEHPQVRPFEADPERQRNWRRLERQRDIGDVFSTIQSSLMDD
QDDNAAVLPMDERGWITIYFLFRVWHPSSSPRSSSWSGSSRTRTRTLHGASTRRRSATAA
RHWGEPTEPAAGSVEDEDSSDDGTVSWRRRVRRRLSTPDDEV
>Sgl42113 E3_adaptor/Cullin_RING/DCX/DWD 92.2 15.6
MEKKRVAVPLVCHGHSRPVVDLFYSPVTPDGFFLISASKDSTPMLRNGETGDWIGTFEGH
KGAVWSCCLDTHALRAATASADFTAKVWDAITGDVKHSFEHKHIVRSCAFSEDTHLLLTG
GMEKVLRIYDMNRPDAPPREVDKSPGSVRTVAWLHSDQTILSSCTDIGGVRLWDVRSGEI
VRTLDTKSSVTSSEVSQDGRYITTCDGTSVKFWDANHFELVKSYEMPCTVESASLEPKYG
NKFVAGGEDMWVRVFDFHTGEETACNKGHHGPVHCVRFSPGGESYASGSEDGTIRIWQTG
PLSQEENDVAATTASSGKVRAAAAAEEVSQKMEGFHIADEGKAKEEVTNAK
>Sgl42132 E3_adaptor/Cullin_RING/DCX/DWD 67.4 9.0
MGSQTNWEADKMLDVYIHDYFVKRKLHASAKAFQQEGKVSTDPVAIDAPGGFLFEWWSVF
WDIFIARTNEKHSDAAASYIETQISKAREQQQMQQQKSQQQQQQMQMQQILMQRQAHQHQ
QQQQQQQQPRRDGGQLLNGSANGIANSDPLMRQNPGSANVMAAKMYEDKLKLPLQREASE
DIKPRFGDNVGHLLDPNHASMMKSAATGGQHQGQSLHGNAGSIPGNLQQYQNRSPQLPLS
GQDVKPEINPMINARAGGPPGSEGSLIGVPGSNQGGNSLTLKGWPLTGFDPLRPGVLPPQ
KSMMQSPQPMHQLQLQQQQLLMQAQQNLASPSMDMEARRRMILNNNRNVSLGKDGQLTSV
GEVVSNVGSPVQAGCPVLPRGESDMLIKQQLPNNQSQPQNPQNAPSGQSPQIPNQTDKTG
STSMTMDANLSNSFRGNDQASKGQMGRKRKQPNSSSGPANSTGTANTAGPSPSSAPSTPS
THTPQDVMSMPNLQHNGGSSKPSLMFGSDSAGTMTSGPNQLADMSRFGDEATLDDNVESF
LSHEEGDPRDAMGRGMEVSKGFTFKEMGLIHASAGKVNCCAFSSDGKLIATGGHDKKVVL
WHTDNQSLKASLEEHTHMITDVRFSPSLSRLATSSFDRTVRVWDADNTGYSLRNFTGHST
SVMSLDFHPTKEDLICSNDSNGEIRIWSITNGSCPKVSEGGTVQVRFQPRTGKYLAAASE
LGINIIDVEPFRLVQQLQGHAQKFHSVCWDSNGENLACVSEDMIRVYNVGAGGKFQRVHE
LPCTGNKFNTCVFHPVYPSLLIIGCYQANFSPLIYFIWSIFVKISKLHCTPFPFLDHITQ
VLKGKDTYLPNSDCYVLKH
>Sgl42142 E3_activity/RING/RING 34.4 8.6
MAVSSEEPTRESADHYPLLMEGCNSHRNDGHVIDIERGGEASSSNSPDLEYSRGVSPHNG
PREINDMQAPHNEPPSPSPSRTVSRSSSFVRRSEGIGRRNWSPFNSGFWISVELVFTLSQ
IIASLTVLCLSRHEHPQAPLFAWVVGYTTGCFASLPVLYWRFLHRNQGAERGALQANQAS
PRANSPSDPNSYVTISLSQSSEHENHQSAPESTFEGQSMEMAMTRVGLLMDHFKMALDCF
FAVWFVVGNVWIFGGHASATEAPNLYRLCIVYLTLSCIGYAMPFILCAMICCCLPCIISV
LGIREDLNQVRGASEECINALPTYRFKAKKDEGGSTGQTEYETEGGVVAVGTEKERAISG
EDAVCCICLASYIDDDELRELPCTHFFHTECVDKWLKINATCPLCKYEVVERDDTLSSPT
NAAPQS
>Sgl42195 E3_activity/RING/RING 28.2 2.7
MELKAVKDAFDPVTKKQKLCSSKFHEVVEQLGQKIEQALLDLHSADASSSYPDQKAIVTD
LKTNLKDIAHATQLESSQKEVNGALSKYPKQLEKHFNPDISKAYRNVDFDNHLINQIIIS
HLYREGLFEVGDCFADEAGEKEATALKSPFIEMYHIHQAIKSHNLEPALQWASANCDKLR
QNGSDLELKLHRLQFVEVLQNQGRDDALKYARTFLAPFATSHLAEIQKLMGCLLWVGKLS
ISPYPDVLAPINWEKLGDEFTRQFCNLLGQSFESPLSVTVAAGVQGLPTLLKLMNVMMSK
KQEWQTMKQLPVPIELDKEFQFHTIFVCPVSRDQATEENPPMLMSCGHVLCKQSITKLSK
NSTKTFKCPYCPSEIEASHCKQLYF
>Sgl42256 UBD/Alpha-Helix/UBA 17.5 0.0
MTPVIPCSVSNISFIPGTSFITRKSRCLTRYNRSVNPTIQSVSSKKHFIALPQSLTVFQH
LKTVSSRIQRLSATGTDVAVEEQGSDVADEASSTPPDQVTNEQPTTKSDSSSAPTRAKRR
LGRKSEMPPVKDEDLVPGTVYTGKVRSIQPFGAFVDFGAFTDGLVHVSKLSDTFVKDVND
VVSIGQEVKVRLVEVDNDTGRISLSMREDDSNNKPQQNKDGSNDKPRSARRNANLNSQKR
RSEVKKTSKFVLGQDLAGTVKNMARSGAFISLPEGEEGFLPRSEEPDDGFGNVMGETSLE
VGQEVNVRVLRTTRGTVTLTMRKDEDVKKLDSKLNQGVIHTATNPFVVAFRKNKDIAAFL
DEREGVEEPAETPASIEVESSTENVAETTTEEPDSEVIATSQDIPDEEDVATTTKEEAEE
PNSEVVATSQDDIPDEEDAATTTKEEVEEPNSEVVATSQDIPVKEDETTPVSASPLTEEK
EKTSEASSITQEVVAETQVESISAKEDQPVEIPTDEAKMETLSPEDNQSIDASSAEDEAT
ATLSPAPLAEDGDTKTEESPVNQETVAETQAETVSAIEDVPVEIPTSAASVETASPEVNE
SINGSSGGPNGSSPLENVSKAAISPALVKQLRDETGAGMMDCKKALSETGGDIVKAQEFL
RKKGLASADKKASRTTAEGRIGSYIHDSRIGVLVEVNCETDFVSRGDIFRELVEDLAMQV
AACPQVEYLTTDDVPKDLVDKETEIEMQKEDLLSKPEQIRSKIVEGRVNKRLAELSLLEQ
PYIKDDKVVVKDWVKQTIATIGENIKVNRFVKFNLGEGLEKKSQDFAAEVAAQTAVKSAP
ATAEEPAQPAAAEPEKAVEKPPTVAVSAALVKQLREETGAGMMDCKKALAETGGDLEKAQ
EYLRMKGLSSAEKKSSRLAAEGRIGSYIHDGRIGVLIEVNCETDFVGRSEKFKELADDMA
MQVAACPQVQYVSIEEIPESIVSKEKEIEMQREDILSKPENIREKIVEGRISKRLGELAL
LEQSFIKDDSVLVKDLVKQTVASLGENIKIRRFVRFVLGEQAESSNTETEE
>Sgl42271 E3_activity/RING/RING 30 6.8
MITRVNHLFLIIFIIISIKLASAQEDDHEQQHTPTSSNFQPSLFVVIGVLSFMFSLTSIL
LIYARFFYRQPSAIHSISRNQETNNAAVFGNDTRFSGIDKKVVDSLPFFKFSSLKGAKQG
LQCAVCLAEFEDVEVLRLLPKCKHGFHIECVDLWLEHHSTCPLCRQTVSAEDLTTFNTSS
SMRFITNGGGERQKSDVGEDAAAVGTAAASSASVELFLDRENNSVERCSRFSSFRRVFST
KVEDEVVQIQVDEKVLNRLNHQIVVSDVVFKHRWSDVSSSDLMFLNSEMLGVMSSDRVTC
SSNNNSNDDDADAEYRIINIRDEIERKKNFEDRVEQIKGCNSKEGFEELNGTNMNSNHTR
RNSLILPGDKRSMSEITALSRFKEMMSMKNKLRQCLTDNNSDNCNINDDDLIKRRKKWFP
IAKKTVQWFANREKNKSQQPQQSQGTSQTSDQSIDKSVP
>Sgl42298 E3_activity/RING/RING 26.9 13.8
MAAMSFSNYSVDLQFDLDEALDCSSTTMIIKPPSSTSSSPPSSSSHNYVINDDDNNIISD
DNNNNNSSSSLISRVYMELPTVAVGNDSVCCVCMEGFLQSHDHLHQINGAKQLPCRHVYH
PDCILTWLSSSHHSCPLCRHIIFHHDDDDDHQTFKSS
>Sgl42299 E3_activity/RING/RING 35.1 4.6
MATFSFDGVFDLDDALTMPMISTPIISPLTIVNVAETLLTFPTVATPNDAVCSVCTENFV
PPRGGGRRIPCGHVYHDDCIATWLSVRDSCPLCRVVVNQSSQIKKTSC
>Sgl42300 E3_activity/RING/RING 40.9 7.6
MNSNILYSYPINIHQTFDLDEALTMPPSPILNISHNVPPDHSSCATLPTVTVENNVICSV
CMETFRQSAKRMPCGHVFHATCIAPWLSINNSCPLCRNIVFGNAS
>Sgl42324 E3_adaptor/Cullin_RING/DCX/DWD 48.2 9.0
MGNKIARTTQASATEYYLHDLPSSYNLVLKEVLGRGRFFKSIQCKHDEGLVLVKVYFKRG
DQIDLRDYEKRLFQIREIFRSIENPHVWPFQFWQETDKAAYLLRQFFFNNLHDRLSTRPF
LSLVEKKWLAFQILVAAKQSHEHGICHGDIKCENVLVTSWNWVYLVDFASFKPTYIPDDD
PSDFSFFFDTGGRRLCYLAPERFYEHGDDMPVAPDAPLKPSMDIFAIGCVIAELFLEGHP
LFELSQLLAYRRGQYDPSQHLEKIPDPGVRKMILHMIQLNPDARLSADGYLQSYAGLVFP
NYFSPFLHNFYSCLRSLDSDARVVMCQSAFHEIVKQMTDNKFSIETSGGIRNSPGKTSQQ
TVSQQVQCHPKVALKKDLLTRGLANERFELFGDLNALLRDVDHSNHFSTDKTNKDDLSKI
NILQSQEVYRLQIPDLLQSISDVFKRREHAFLKTITIDDLKSLMSEYDDESDTYRMPFLQ
LPSEDMSCEGMVLITSLLCSCIRNVKFPQLRRSCILLLKYSSIYIDDEDRLQRVVPYVIA
LLSDTSAIVRCAALETLCDILPLVREFPPSDAKIFPEYIFPMLSSLPDDPEESVRICYAS
NISKLALTSYGFLVHSIRLSEAGMLDELNAPQKSTPSTDNGQALKVYSNAQLAHLRKSIS
EVVQELVMGPKQTPNIRRALLLDIAGLCCFFGQRQSNDFLLPILPAFLNDRDEQLRTVFY
GQIVYVCFFVGQRSVEEYLSPYIEQALSDTTEGVIANTLDCLTVLCYSGFLRKRVLLEMI
QHAFPLLCYPSQWVRRSVASFIAASSESLGAVDSYVFLAPVVRPFLRRQPASLASEKAVL
SCLKPPVSRQVFYQFLENARGSDMLERQRKIWYNTSAQTNQWGTVDFPRQDDELLSLENW
PDTNGNLENDNAVGFPADQIDSTECDSTEAKLKALRGYIHNSSSTIDIRDHISSDKLQFS
GLITPQLNSMNSLLHEKSSENIPLYSFSLDRRALGNPQAASDTSLQPNMVGLGSSTTPWM
DPVNKPFGMASSVPAPRAVSGSFSLANGSKQFHRVVHEPESRESDPTSYVSSKLQDLGIS
SNSSTRGGSMSMEDVPSSSDMAGSPSVSWTSALPDSGWKPRGVLVAHLQEHRSAVNDIAV
STDHSFFVTASDDSTARVWDSRKLEKDISFRSKLTYPLEGSRALCTTMIRGSAQVIVGAC
DGKLHMFSVDYISRGLGNVIEKYSGVADVKKKEVGEGAILSVVNYSAETSSSHLVMYTTQ
NYGIHLWDTRANADSWMLKSLPEEGYISTLVTDPCGNWFISGSSRGVLTLWDLRFRIPVN
SWEYSRPCPIENMCLYVPLPHTPFSAMGRPLVYVAAGCNEVSLWNAETGSCHQVFRVPGN
DGDSEFSELPWALARPQNKANPKSDPRRNVNLKYRVDELNEPPPRLSGMRSLLPLPGGDL
LTAGTDMKIRRWDHSRPERSYCVCGPTVKGLGHDELYESKSSFGVQVVQEMKKRPATTKL
TTKAVLAAAATDPAGCHRDSILSLASVKLNQRLLLSSSRDGAIKVWK
>Sgl42361 E3_adaptor/Cullin_RING/DCX/DWD 48.2 9.0
MGNKIARTTQASATEYYLHDLPSSYNLVLKEVLGRGRFFKSIQCKHDEGLVLVKVYFKRG
DQIDLRDYEKRLFQIREIFRSIENPHVWPFQFWQETDKAAYLLRQFFFNNLHDRLSTRPF
LSLVEKKWLAFQILVAAKQSHEHGICHGDIKCENVLVTSWNWVYLVDFASFKPTYIPDDD
PSDFSFFFDTGGRRLCYLAPERFYEHGDDMPVAPDAPLKPSMDIFAIGCVIAELFLEGHP
LFELSQLLAYRRGQYDPSQHLEKIPDPGVRKMILHMIQLNPDARLSADGYLQSYAGLVFP
NYFSPFLHNFYSCLRSLDSDARVVMCQSAFHEIVKQMTDNKFSIETSGGIRNSPGKTSQQ
TVSQQVQCHPKVALKKDLLTRGLANERFELFGDLNALLRDVDHSNHFSTDKTNKDDLSKI
NILQSQEVYRLQIPDLLQSISDVFKRREHAFLKTITIDDLKSLMSEYDDESDTYRMPFLQ
LPSEDMSCEGMVLITSLLCSCIRNVKFPQLRRSCILLLKYSSIYIDDEDRLQRVVPYVIA
LLSDTSAIVRCAALETLCDILPLVREFPPSDAKIFPEYIFPMLSSLPDDPEESVRICYAS
NISKLALTSYGFLVHSIRLSEAGMLDELNAPQKSTPSTDNGQALKVYSNAQLAHLRKSIS
EVVQELVMGPKQTPNIRRALLLDIAGLCCFFGQRQSNDFLLPILPAFLNDRDEQLRTVFY
GQIVYVCFFVGQRSVEEYLSPYIEQALSDTTEGVIANTLDCLTVLCYSGFLRKRVLLEMI
QHAFPLLCYPSQWVRRSVASFIAASSESLGAVDSYVFLAPVVRPFLRRQPASLASEKAVL
SCLKPPVSRQVFYQFLENARGSDMLERQRKIWYNTSAQTNQWGTVDFPRQDDELLSLENW
PDTNGNLENDNAVGFPADQIDSTECDSTEAKLKALRGYIHNSSSTIDIRDHISSDKLQFS
GLITPQLNSMNSLLHEKSSENIPLYSFSLDRRALGNPQAASDTSLQPNMVGLGSSTTPWM
DPVNKPFGMASSVPAPRAVSGSFSLANGSKQFHRVVHEPESRESDPTSYVSSKLQDLGIS
SNSSTRGGSMSMEDVPSSSDMAGSPSVSWTSALPDSGWKPRGVLVAHLQEHRSAVNDIAV
STDHSFFVTASDDSTARVWDSRKLEKDISFRSKLTYPLEGSRALCTTMIRGSAQVIVGAC
DGKLHMFSVDYISRGLGNVIEKYSGVADVKKKEVGEGAILSVVNYSAETSSSHLVMYTTQ
NYGIHLWDTRANADSWMLKSLPEEGYISTLVTDPCGNWFISGSSRGVLTLWDLRFRIPVN
SWEYSRPCPIENMCLYVPLPHTPFSAMGRPLVYVAAGCNEVSLWNAETGSCHQVFRVPGN
DGDSEFSELPWALARPQNKANPKSDPRRNVNLKYRVDELNEPPPRLSGMRSLLPLPGGDL
LTAGTDMKIRRWDHSRPERSYCVCGPTVKGLGHDELYESKSSFGVQVVQEMKKRPATTKL
TTKAVLAAAATDPAGCHRDSILSLASVKLNQRLLLSSSRDGAIKVWK
>Sgl42442 E3_adaptor/Cullin_RING/SCF/F-box 13.7 0.0
MMEWDSSSSDDSGVDEEEGFLLNDGGSMPFPIQNLLEAAPCGFVVTDALEADHPIIYVNT
VFEMVSGYRAEEVIGRNCRFLQCRGPFAKRRHPLVESAVVADIRRCLEDGVEFQGELLNF
RKDGSPLMNRLRLVPIYGDDEIITHFIGIQLFSEANVDLGPLPSYTAKESLRSSDLFRSS
LSSFQPFQSRERNVCYEVCGLLRLSDEVVALKILARLTPRDIAAVGSVCRRLYELTKNED
LWRMVCQNAWGTETTRVLEAVPGAKRLGWGRLARELTTLEAAAWRKVTVGGVVEPSRCNF
SACAVGNRVVLFGGEGVNMQPMNDTFVLDLNASNPEWRHVKVSSPPPGRWGHTLSCVNDS
NLVVFGGCGTQGLLNDVFVLDLDAKQPTWREISGLAPPLPRSWHSSCTLDGTKLIVSGGC
ADSGVLLSDTFLLDLSLDKPVWHEIPAAWSPPCRLGHTLSVYGGRKILMFGGLAKSGPLR
FRSNDVYTMDLNEDEPCWRSVTGSGMPGAGNPGGTAPPPRLDHVAVSLPGGRILVFGGSV
AGLHSASQLYLLDPTEEKPTWRVLNVPGWPPRFAWGHSTCVVGGTRAIVLGGQTGEDWML
TELHELSLASSVIHEDQL
>Sgl42501 E3_activity/RING/RING 34.3 8.6
MPRNNRNRQNAVVGDNFNPSISDDIRQLNSPEIPTKSNPKFLSLVLQALIMAFVISLFFI
FIGVAAIIFLHLCIAGGALRHRRNRRRPDSGNLDSSSGYSLELLETLPKSRFKGCEVCAI
CLDNVLEGEICRVLPNCKHVFHLNCVDKWIVKSPVCPVCRSSVKSVDHHEGKGRGAFDWE
HLWSACG
>Sgl42509 E3_activity/RING/RING 30.2 10.4
MERNPLAPLAEQHHNNVDSSGLNLDNKISPSIILIIIILAIIFFVSGLLHLLVRFLLKPN
ERNPDEFSDNVTALQGQLQQLFHLHDAGVDQSYIDTLPIFQYKTIIGLKDPFDCAVCLCE
FEFDDKLRLLPKCSHAFHMDCIDTWLLSHSTCPLCRASLLQDFGTHNHGLGPGIGFGYGL
SPVVCVLESGANTVESSMELERDSTYSGPSLAQQQGEFGSNRSDVGRKSSGSVQEIGKSE
DSNNKIVTVKLGKFRSVEGGEGSSDINYFSNNNNNNNNNNNNVSGNGNRNGGGVSSNELG
SRRCYSMGSFAYVLDETTSLQVPIRTPMKKEKNVAKKGNLKIGHRVAMSEYGGGGDSMRE
FNGIEFQGKGNESSRKKESFSISKIWSTGGGDKKGKGNGNGNGIGIEVDQSSRRTISEFE
IDVSELGNDEETQSCYSVDSLANNPNTTTSSSSTRRTLLWLMGRQNKIVHNHSSFSSNV
>Sgl42510 E3_activity/RING/RING 12.3 13.2
MRFLSIVGNSLGCSASGERLVSAARDGDLLEAKALLEYNPRLVRYSTFGVRNSPLHYSAA
QGHHEIVTLLLETGVDINLRNYRGQTALMQACQHGHWEVVQTLILFKANIHRADYLNGGT
ALHLSALNGHTRCIRLLLADYIPSVPNTWNLLQNKSKKDYGISEFNASALHQVINKPADG
GITALHMASLNGHFDTVQLLLDLGASVSEITVEDGTTIDLIGAGSTPLHYAACGGNLQCC
LVLVARGASLVADNANGWTPLMVARSWHRDSVLEILSTPQDIPLSTLPSPYLSLPLMSII
KIARDYGWRSSEFVPACQDPCVVCLEGRCTVASEGCNHEFCTRCALYLCTINCASAVAKG
PPGSIPCPLCRHGIVSFVKLPGTRPIPKEIARTSLSLSFCGCSCEKNERTPLTMPLCRPP
PVSSSSSSIRVSPLSSSFRSLSCQRFPSMKLNSGCCIGGSETSPSIISGSVNRSLKNQLS
RCGRVRLRRSSSHTEGRKSWFCSLNQYVATNS
>Sgl42533 E3_activity/RING/RING 34.3 8.6
MPRNNRNRQNAVVGDNFNPPISDDIRQLNSPEIPTKSNPKFLSLVLQALIMAFVISLFFI
FIGVAAIIFLHLCIAGGALRHRRNRRRPDSGNLDSSSGYSLELLETLPKSRFKGCEVCAI
CLDNVLEGEICRVLPNCKHVFHLNCVDKWIVKSPVCPVCRSSVKSVDHHEGKGRGAFDWE
HLWSACG
>Sgl42559 E3_adaptor/Cullin_RING/DCX/DWD 13.5 8.7
MAILHPQTQQQNNFQVHHLPQSNYIDAVRWLAPISAFDKFVIFSLFDSNSSSSTIELHSL
EFTDSSNPKPILSPLSSSSPSLSRTSSLKTSQSLIAFSTFSGSLNFLSPNHTSSGEISLN
STLSLQEKGFHVGPISCIDVLESECVSVGEDGRVNLVGFSGGKPSYRRVFDSNGLVCYTA
VKWASPSEFATGGLGCSLQWWDQRRKPGEPALHFKPQKSASGVVHSIDIHPSRKHTCMAG
GSSGTVFAWDLRWPQQPIVLSGVGISEKPSHPVSESEVWEVQFDCHSQSSNIASMSSSML
PAMMCSEDGILAVLEPGSEPVELLEEPCAINSFDIDKQNYDVICSLEWESVAILTRS
>Sgl42562 E3_activity/RING/RING 24.6 3.6
MSNKGDKETGREGHVQGDALIIESISSNNASMGVTTRRRSMIKSKKSEASSVAAKNPIKV
GVSENEPRNSGAKTASTSGSIQIASTEVPLTTKRRSAVKRAVPSEAQNKETGGRLETDQV
AQGSSVGKQPDSPVRKSKAKTATSQQAWKEKAQPESSTKKVSPRKQQGQASGSTSKPPTN
TTNASKQNKSANQKQGSSKKAVPKDQTPHGKQAKHKPSTSASQLNPSDYPKYHIEWKGFQ
EPHRLEVSCCLCENDIRVAPMETNLDSGFYEFSAIPVVAILPCGHVYHNDCLSRGELEQQ
QTDPICVFCDSL
>Sgl42666 E3_adaptor/Cullin_RING/SCF/F-box 13.1 0.0
MNTEDNRTELQGNSDWAELTHECLLNILSRLPLEDRFKGAMLVCKPWLEACKDSSLNTIL
DLEPYFESLTESTRWWSPEFERKIDSILLFVADSCNGRLTKICVRHCSDLALMFAAQRCP
ELEVLSIKSSQSVSDAAMAEVAKRCPKLKELDISFCHEISHESLSLIGRSCPNLKVLKRN
FMNWLDASQHRGIVPNEYLNACPQDSDSEAAAIGKCMPNLKHLELKFSKLSGKGLALISE
GCLNLEYMDLNGCANLTSRDILNASTNLKRLETIKKPNFYIPRSVYHTERTYSQNPNTPE
THHKTNPFTIWPRRSLWSRLSMVDYHARIDLPCKFHNPQCS
>Sgl42688 E3_activity/RING/RING 13.8 3.7
MTLEILFDCAKVRKKLTSDDLYEINTPTHDYGQFIDLYRSIAKHPTRETSQIPHLPTEEE
MSRVDFPRVDWDTDPTAEDLEESNSMRKKRGQKAPKRGVGGRVSGSSRGTKKKRTFRPCF
LVSMKVRQASVLLLYKRENVYCAGARDMFGNWWDFSINGGVLFPGSRGLGFEESYTKMEL
LNKRATVGLQQLEHAVFVFSNPAAHSVDDRKIAAQILIAVTSEAGRFKILERLFDDALND
DTGLSNVDVDGKRQRRLEVASKKYDVAMFQLGVDQFPENQSTMKRDEILHDDFAAASSFS
TSNSAHSVCKKKDDGNALTENDFNNSGNMPDSNYREQNEKVQPLKEEFSPLPAYGQSILV
SLTTRCVWKGVVCERAHLFRIKYYRNFDKPLGRFLLDDLFDQSYRCRVCEMPSEAHIHCY
THQQGILTISVRKLTEFPLPGERECKIWMWHRCLRCPRVNGFPPATRRIAMSDAAWGLSF
GKFLELSFSNHAAASRVASCGHSLHKDCLRFYGCGRMVACFRYAPIVVHSVYLPPSKLEF
SCANLEWIQREANEVNDEANRLYTEVRNLLNGKFLSSKSMENNSRACGLKKHILELERIL
EKEKEELEESLQKVLQMEGWN
>Sgl42711 E3_adaptor/Cullin_RING/SCF/F-box 14.3 0.0
MFRRPFRRWDPHEIYNAHCHSYFLRLRSSNFRFTNLMILRDENYMKHVEEFNNIVSSRRT
LFVTKEKDISNYQAGPAVPKAIDVQTKEVQPVLMEVTINTELDDRCKAVGAVEQGANTSL
SMEPSKGEQSLHSFVFTAGGQVKNSKGKGWRRRERMEGDGGMEVDADGGRVMVGNKRSVE
CDVDSVAGGEDARKRIRSSSEAQTLPTSPTEVVRRLKRWATAAAPDLIFVSETMISKAAV
EGLKERLGFSSCFRVSSFGKAGGLGIFWKSERVDFTILNFSNNHICGEVVVGEKRWCFVG
LYGWPGVSDKSRTWELLRSLTRGTTLPILVGGDFNEILSMEEKEGGSTQVRREIDFFREA
LDDCELRDLGFVGQWWTWERGKTIEKRVRERLDCFVASPQWCSLYPRAHVEHLLRFNSDH
APIILRTINGRRKKKKKGKHFKFETAWLLDDSCEEVVREAWRDGGCESVDHRLVGVGSRL
MAWSRDKFNDLGTKIEDLEKALREAQKKPISQESCDEFQFLSPTNSPMETNNSRNQNPNT
IKNLEELIFHEVFPKLPAESLLRFKFVARHWDAFIKSVEFLKTHVRHLPSHLNSNSSRSS
VLILDSRRFFQFLDYGEANFDDSSCKCLSFLISPCVDEEGIDRKIFCRRHVIGSYDILLS
SCNGIAFMVSPSEDADLSCRFGFHYVLYNPLLGPHPLVKIPHPDDNRLGSEDPWPFDSYG
FGFGYVSSTEDYYIVAINLPRGLKIVVSLYSLRSKTWRNDAIALSLSPEKVGSILPLVFK
NKYWYRNTGTLVKETLHWGIQQGLGHHIIFAYNLATLRYSRILYPAKFIATQDNVREMGL
CCLDDCLCAWAQNRRNTVELWRRKGSNWSGLFRIKTVHRVCDFFGFNKTDHFLIFSDVNQ
ANNKAGVDYKLYLSNFMGNKRLIGRHIRQKIWNAVNYVPSLESFQAMNSETNQ
>Sgl42712 E3_activity/RING/RING 9.8 34.3
MKARSSSMVDDDTLPQINQFFKTLKSEKPPISPKFKQKRMSNHHQKRSVSDLIILERGDY
SSEIKHNVVIDLNDDDYGGNSVKIIDDNDDDDDCVFVKSEVNLTNNIGNDKKYPICIENC
EKEMKSNGKSKLRKNFTIDLDDSVQCVDDYDDNDDVRVINVKSSSRKRRNTFSVFEIGES
SGSKREEETDEVVTVVEPVEVMFLCEICADSKPRKEAFKIKGCSHSYCSDCMKTYVASKL
QDGVSVINCPVPSCSGVLEPEYCREILPFEVFTRWGNLLCESVILASQKFYCPFKDCSAL
LVDDGGEKVTSCECPSCYRLFCAQCKVAWHAGIGCAEYQSLSKDERNSEDIMLRKLAKSK
KWQRCPKCKFYVEKSEGCLYMKCRCGIAFCYHCASVFKNPNYHYCNKCRR
>Sgl42721 E3_activity/RING/RING 24.8 13.0
MQYCSGEDAIHNFRISLVENILVKNLWHDFLFHSEAKHEDISTSSNNEDTFSDTSKVLVK
DRSEIKQGQLHDLGRCIIDVLCAMHSLECKLLAPFCDAFQDCCLETFQQAESVKVPSGKT
ERAVKFLLLVQKYTNLNSESWPLSYLVGPMLERSLPLIISLDSPEAVNFLSTVVSIFGPR
KIIPRFIQSEGIADDSATDLAEKELSKFLKWDVIISYAANMHHSTASCIGRLATFIEKAR
KLAMKKSLLDGNEMFEIACWRHELLDFLAISIMQSTSHFTDSDLQFIRAVLGGTSEDDAI
SFLSKTSVIQIYTDMFGKLIAFVMESPISCVRNFGSLLCTLLKSTTSEIQESANVARMAY
ISLEVLKSTPFSLKSYCEGSDLLPAIGGIVFVIDWEYHISRESDAKFNQTPVGSIIPRQD
FGKMMHAFRTSMDIQYWRSLLPQSRVTLRSLLIQFIRSSIFGQDGFVADMITTLCCKWIV
EVGKHLCLNLLEEQKLMDMLLSVDESWPLWITPDASNSWRNFSVKAERVLTDVNISQSQL
FVALVDKLISEMGINRVIAGSHLQVLIAEERASNEPIASQSEFSRAWVVAEMLCSWKWYS
GSALSTLLPSLSSYAKKESVDDLICLFDPIVNVLLEGALICGTKSQLSIFNTWPPSNKDL
DDIDEPFLRAWILPPLVSVLAHFLCHNGSNDLVKDFRETVVRDWLEKTLTFPSLISWTSG
MKEWFQLALSCYPLSTTADMGHLKLDPSSSEKKLILDVFRKQRHDGNSLIVTNELPVVSL
LLSRLIVIAVGYCWKDFHEEDWTFVLAHMRSWIELVVSTLEEAAECLDLEIGNGSGDNLD
LVINKLNHIMLNLDPSLVNVATNAFNAFSLVMELVGCDPSDNTEKLPVLKTEACQHTIDL
IQEGVLRIFFSVGVAEAISGPMSCESLSIIARGQHAYPHFWNLVSSITVKTSTLSREQAF
KAVELWGLRTGAISSLMAILFSSKPVSDWQLASFVLLSSQPFSNWALMEDHVSDSLTESS
TVDIGSHGIDLSSENNFPLREEIHILIHKLPLEILDMDLESQERVHVYFAWCLVLCYLSS
SSNREKLVQYIQESASSAILDCLFQHIPFELGASLVSKKKELETPPELLNIAAAATRAVS
TGSMLFAIESLWPIGPDKMASLAAATYGLMLRVLPAYVRVWFNDLRDRSASTAIESFTKT
WCSPHLMADELSQIKKSDFVDECFSVSVSKSANEVVATYTKDETSMDLVLRLPASYPLRP
VDVECVKSLGISEVKQRQWLLSMMSFVRNQNGALAEAIRIWKSNFDKEFEGVEECPICYS
VIHTANHSLPRLACKTCKHKFHAACLYKWFSTSHKSTCPLCQSPF
>Sgl42793 E3_activity/RING/RING 36.1 8.1
MAAIDTTLTLGEGSNAAGPSSSASKKPKRFEIKKWNAVSLWAWDIVVDNCAICRNHIMDL
CIECQANQASATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNSEWEFQKYGH
>Sgl42847 E3_activity/RING/PHD 40.9 25.3
MAEFSNQGHQLNYTNNFLFNDKVEVRSLEDGFQGSWHAGVVIACDSRYVKVKYKHLLLDD
ESDHLTETVEVDSTEGVLSSSKSRNRGRIRPIPLMGKVSKLDLHYGLCVDCYYKDAWWEG
VVFDQDNGSSKRNIFFPELGDEMTCGIKCLRLTQDWDEVTGDWNPRGRWWFMVMFEEFEK
NNYIPVSLKQIWYDTRERKEFGEIGEWPSPLWHELIEQVINENVQLTVNEFLTRYLSSEA
TSALDATLNHHPIPVNYVSAVPSAMDVILQGVDFTREIEGDLAMVGELVENAALAVDLLE
SSPTSMKIVPVQPMALSAICSDQEGLDSDTIYESEFTTNSRSNENKQLRRNKRKLEPDES
RINDLKPDCCPQSMYDYIQRDRPGSTLTTKVRCHLLYLGYKMEHASTRKYVQYTSPEGKK
FCALRACLNFELAKEEISPQAAEDVQTGKVSSAFNLNCTSPVRVASTSKVCDKKSQAKLL
DLDIEPKFCPEAVHKYVRSSEKRYPCRSELQDEVRSHLLAVGWNFWGKVKQGREEWRYDS
PTTNKTYYSLMSVCKAITNGVEILGSSPSEDANNENLKEHSGGELLLSNKEVSGNPLSQK
RSRKFPRAFRKCKASKLQRRKPDGFEHSMPSLLGIGEKEQEVGNNGSAKRHCHSMTTSFL
SKKNKVLGKVKNCSDSSNLSQVPRSSKRVRQAGPSISSQAPRTVLSWLISNGVVLGREKV
YYYRQDANRPSAEGRVTCSGINCSCCGRDFTISGFEAHAGSYSLWPAANILFDRDGKSLV
HRQLELVRQKIRISRGPLEKSKGNGQDNWNDHICSVCRYGGELILCDRCPSSFHASCLGL
QEIPEGEWFCPSCCCGICGDSYSDMNTECSSDQRILSCYQCERLYHACCIEKTDMIKLDV
PPTENWFCSKMCEKVHWGLQQLLGKRIVARHNDLTWTLLKPMDYGDIHRDDCDLSSLTEN
YSKLSIALEVMHECFEPVKEPESRRDLVEDVIFCRGSKLNRLNFRGFYTVLLERNDELIS
VAILRVHGGKVAEIPLIGTRVKYRQLGMCRLVLQEIEENLIKLGVKKLVLPAAPSVLKTW
TTAFGFVQVTESERSEFLSYSFLDFQDTVLCQKVLRKLPAPLPQLTRVMPRAHYQDHRIV
EGRSIIADPEGNSVSTEVSEGSEIVDHGTLASGLEDKLNSNGGDGGGGDGQDMPIVMITD
PTNRECESSTFLDLIEQKIERDKCGGFEKFYERKKAVELRSSAPKSNCPNLEISAIMATQ
MSKKRKFVADGVFYAELNEVFTRELAEDGYSGVEVRVTPMRTEIIIRATRTQNVLGEKGR
RIRELTSIVQKRFKFPENTVELYAEKVNNRGLCAIAQCESLRYKLLGGLAVRRACYGVLR
FVMESGAKGCEVIVSGKLRAQRAKSMKFKDGYMISSGHPVNEYIDSAIRHVLLRQGVLGI
KVKIMLDWDPKGKVGPQKPIPDVVIIHPPKDDDVYARFPVLTQEVELVDPVVA
>Sgl42850 E3_activity/RING/RING 33.7 10.0
MSNSPNYHDFGPPSLNDQSNNNNQYNLSMLYFGFLVVATAGLILAIYHCIVFNFCTDYPS
SLLLRHSTSSSGGGGSGSTPSHHGFNASKLKVVELESVLFKYNKKEKGVQLQTEQEEEEE
EEECVVCLSVFEEGEDVRKLVKCKHCFHAPCIDMWLYSHFDCPLCRATLGDAAAAAAATG
VSVPPSEGNSGARYSDSGVLPV
>Sgl42874 E3_activity/RING/PHD 34.8 9.9
MDGGGGAQYNPRTVEEVFRDFKGRRAGMIKALTTDVEEFYQQCDPEKENLCLYGYPNEQW
EVNLPAEEVPPELPEPALGINFARDGMQSKDWLSLVAVHSDAWLLSVAFYFGARFGFDKN
DRKRLFNMINDLPTIFEVVSGNAKKTSNSREKTTISNHSSTKSKSNSKSAKYSSKAAPAV
KDEEDGLDEELEDEHGDTLCGACGENYASDEFWICCDICEKWFHGKCVKITPARAEHIKQ
YKCPSCSNKRARP
>Sgl42881 E3_activity/RING/RING 29.4 13.4
MMGALSTLTSSQLTSLSLSLSTTFHRHHRHLISLLSSPTLFHSHPQPPLLYLSPSKIPPH
CPPPSLFPPPPYTVLIPNIFTSSSNKVRLRDLDSVLLLLFFCEVRQHHPTLLEETESPTR
WQEILKHYGSDTMLNNNMSAGFAVSLTMSPFQVLGAFVDLVVKCRKFVGSKGCSSNTEAK
REVAASVDAVVALPSVTIELGGGGVECVICKEEMKEGRDVCELPCEHKFHWKCVLPWLSK
RNTCPCCRFLLPTDDVYGEIQRLWDAIFKLNTQHVPLGVDDIYN
>Sgl42895 E3_activity/RING/U-box 69.8 0.0
MTTVAVAVNIGGNSRGNGSKRAVKWAVENLYSQSNHFVLVHVMPTITHIPTPSGNRISIT
ELDTKVVAKYMEDVREKTQAIFLQYKRLYKPGEFDFETLLLEHDNVAVALVDYVKTSSVR
SLVLGSESLNRFWRRIKGHRIPQSLLKSTPDTCDIFIVSKRRVKTKLASSMTSSAAIFTD
TQTESRRNGNDERPVIVTTGEIPLHSSSSIELSTGASHLSESSLSNSSPEAHERSNYNNV
HDDDLNAHAPSVISHTSTNTDLSSIGQMSLADSHVSYEQFDLNNEVEQLRLELQTTLALY
NRACEDLVHAQKKVRILSSECVVEAEKINAATEREENLRKFAEHEKLKHLQAEKDAQAAK
NLLAKESYERQIAELNALKEFKERQKIVDVLISNERRIRRYTTDEIKAATDNFSESKIIG
EGGYGKVYKGTLDHTRVAIKVLEHDATDKKEEFLREIRILSQLCHPNIVLLLGVCSEMGC
LVYEYMENGSLEEHIFRHNRRSPLPWFARFRIAFEIACGIAFLHRRKPEPIVHRDLKPGN
ILLGRNYVTKISDVGLAKLVSDNIPDSVTMFGNSLLAGTLYYIDPEYQRTGTVRPKSDLY
SFGIILLQLLTARSPNGLLLVMENAIASGTLSYILDDSVKDWPLAEVEELTKLALECCKL
RCRDRPDLETVVLPTLKKLADVADASMKVVQNSIFAPSHYFCPILHEVMDDPHVAGDGFT
YERRAIEAWLERHDISPVTKQKVAHFNLTPNMTLLTAIQEWKSRLASKHT
>Sgl42900 E3_activity/RING/RING 34.2 7.4
MSSTVPQQRSPTRNFNQYWCYQCQRVVRISSDNPSGVVCPRCNGHFISEMEIPRPRLVLD
FTYDDDVSSPHARLLEALALMLDPPVRVPTREQHDSLAIPQRPRVGSRENDVVLDGPNTG
RPRWVRAPRALARRDDWDLDLGVRPRPRSSWILVRPTGQPLGPAGPLPLPRPLPQDGLSN
ARNYYFGPGLQELIDELTENDRQGPPPAPDSAIEAVPTVKMEEQHAGDAGSDCPVCKEEL
EIGTEVRQLPCKHVYHSDCIVPWLRLHNSCPVCRTELPVVGDQGSSSGPIEIEGRRMIES
ENSSNNEDDVRPRRRCLNWRRLCSIWPFRSSYSRINPRDDDDGHDHNPRTSNAAIFLTCT
LCLMLVIPLLAYSQPV
>Sgl42909 E3_adaptor/Cullin_RING/DCX/DWD 79.4 9.9
MARGLKSSKKTKKKKSKGSTNGEASTSAASASLMPVKVWQPGVDAMGEDEELQCDPSAYN
SLHAFHADKPSLNSIGIFKVSNISGKRRDLVPKRDADGSDMDSDSDSDDDKDENELGPPI
LQLHKVAHQGCINRIRSMPQHPHISATWGDTGLVQVWDFSAHLNFSAESETGTSHQAPLS
VFRHKDEGYALDWNPLVPGRLVSGDCQNSIYLWEPVAESKWNVDKNPFIGHTASVEDLQW
SPYEDNVFASASVDKTIAIWDLRLGKSCATSFKAHDADVNVISWNRLASCMLASGSDDGS
FTIHDLRMVKQGDSSVAHFTYHKHPITSIEWSPHEGSTLAVTSADNQLTIWDLSLERDNE
EEEEFKAQTEDKVNAPEDLPPQLLFVHQGQKDLKELHWHLHIPGMIISTAADGFNILMPS
NIESNLPPANNA
>Sgl42919 E3_adaptor/Cullin_RING/SCF/F-box 12.5 0.1
MDTLPQQIIIDILSRLTNLSDIASCRLTCKTLNSLSSEISSINLLSSFDQYTQSRSQSSI
LPFKSNFIHFIRESDHLDSISIGVDDLLQSLVYDDVEDDGDDLHLSDEQFVSLWLPFVGC
QLKRLSLTDFWVQSCWRISC
>Sgl42966 E3_adaptor/Cullin_RING/DCX/DWD 82.4 7.3
MSAFSSLTNMSQNPNPNKSYEVPQPPTDSISSLNFSPRANHLIVTSWDNQVRCWEIMQSG
TNVSSTPKAVISHDQPVLCSAWKDDGTTVFSGGCDKQVKMWPLLSGGQPVTMAMHDAPIK
DMAWIPEMSLLVTGSWDKTLRYWDTRQPNPVHTQQLPERCYSLTVRHPLMVVGTADRNLV
VFNLQNPQTEFKRIMSPLKYQTRCLAAFPDKQGFLVGSIEGRVGVHHLDDAQSSKNFTFK
CHREGNEIFSVNSLNFHPIHGTFATAGSDGAFNFWDKDSKQRLKAMSRCSQPIPCSTFNH
DGSIYAYSSCYDWSKGAENHNPATAKTYIFLHLPQESEVKGKPRVGGTSRR
>Sgl42987 E3_activity/RING/RING 31.5 9.9
MTSAAVLFYGRRSRSSRTFDDLGFGSSAPLPLSSSTADLSSSSNHHHHHHRHRHRRGDLH
RRHRHINFDDSDQFRHSFNASHVCGRTPIAESEPHQRDCNEESSSREINNRETVRGLNGR
YHRNNQLPGSVLLARERLVQRLRGVSVSGIRDARETAQSLPSNDQGVVDADWETSVSREE
SASYTNLTDVPVGAHQSVHREPQTKPRGLTDEALSKLHLEVFVEQQNLITQPMSKASTEC
SICLENFVEGNKLINLPCGHRFHTSCLYPWLQTCGECPYCRSCIMLT
>Sgl42996 E3_adaptor/Cullin_RING/DCX/DWD 47.8 1.8
MDCETLKQRYIDASKRHGILPDKGICSSLTMDRMKMSQLEPCVVQLSLDNVRDCDYLPLF
ELFIDMNDSIVDGVDIYIYNNILCIMNGSYVLSLLHALNKKLRAVHLNEQSLEKDFLRDL
SKRGLTCKELNLRSSHLRQLNLTGSFMLLRTLNLDFNTSLSTFQESCFSCMPNLEHLSVC
ATRVSNLWTTSTALSKLPSLIELRFQNCLCCNNTGPCPVSFAQTTHDDTGDGSYDNLFAQ
ASSRHNLLLNQHHSYPEETIPDTSAIEDASFAEYSYWPREDFSEDYEGDAPSYYQELSFP
ELLSNALHNFDLLNNSVVMQQVPTEDRNLSASGLFSNQASSSDDSGKKKYLTHHPSPICF
ENHYRDYIISSLPQLQVLDNLPVNDTDKESAKLRFVKCFEYLPYRRRKKESVVSILNRRE
INSSQNSLHKHKTSCPHMKSAMYHYRSLGAAKVGASAWPSLHPLATSGYVFGDEKKSFRP
RQFEYHPSNSGLMAFGTLDGEVVVVNHENAKIFSYIPSVGAMNSVLGLCWLKKYPSKLIA
GSDSGSLRLYDVQQWQAAVTGRNFSASGFIFNDFDRLTSVHVNATDELFVASGYSKNVAL
YDINTGKRVSVFSDMHQQHINVVKFSNHSPSVFATSSFDQDVKMWDLRQGTIQPCFKASS
SHGNVMVCFSPDDLYLLVSAVDNEVKQLSANDGRVLLDFEIASTGSSQNYTRSYYMNGRD
YIISGSCDENIVRICCAQTGRRLRDISLEGRRSGASMFVQSLRGDPFRDFNMSILAAYMR
PSSNSEIIKVNLMASNDSSSDPSDDETYLPSFSMGG
>Sgl43005 E3_adaptor/Cullin_RING/DCX/DWD 82.4 7.3
MSAFSSLTNMSQNPNPNKSYEVPQPPTDSISSLNFSPRANHLIVTSWDNQVRCWEIMQSG
TNVSSTPKAVISHDQPVLCSAWKDDGTTVFSGGCDKQVKMWPLLSGGQPVTMAMHDAPIK
DMAWIPEMSLLVTGSWDKTLRYWDTRQPNPVHTQQLPERCYSLTVRHPLMVVGTADRNLV
VFNLQNPQTEFKRIMSPLKYQTRCLAAFPDKQGFLVGSIEGRVGVHHLDDAQSSKNFTFK
CHREGNEIFSVNSLNFHPIHGTFATAGSDGAFNFWDKDSKQRLKAMSRCSQPIPCSTFNH
DGSIYAYSSCYDWSKGAENHNPATAKTYIFLHLPQESEVKGKPRVGGTSRR
>Sgl43132 E3_activity/RING/RING 11.8 9.0
MGDHHVVSVDKLITPDTVQPDKGTEVSESTGDNHINVAESSNSHEHKEVEDGDVADEEQP
LIQVLECRICQEEDNVKNLEAPCSCSGSLKYAHRKCVQKWCNEKGDIICEICNQPYQSGY
TAPPPRTNDDTAVDISAQWTVSGAPLDLHESRIFAMTANERRLLEEYDEYGDANANGAAF
CRSAALILLALLLLRHALYVTSPDGDEDDISTFFSLFLLRAAGFLLPCYIMAWAISILQR
RRQRQEEEAIAAGEVAYVIQAGQNGGMHFTIAPGAAVAHHPGSTSIV
>Sgl43161 E3_adaptor/Cullin_RING/DCX/DWD 32.2 0.2
MLTSLQEGRAHRLAIDPGSPHVFYSCGEDGLVQHFDLRTKDFIELFTLCHSTFGRRRNSS
FVHLNAIAIDPRSPNLFAVGGSDDKQVEITGLAFSDISELLVSYNNENIYLFTKDMGWGP
NFAISSVSTCTDTAYEPEDDDPSEATKSVLDTNKKPLPQVYKGHHNCDTVKGVSFCGPKN
DYVVSGFDSGRIFIWRKKDGELIRIMEADRQLVNCIEAHPHTVVLASSGIESDIKIWTPK
AEERATLPANIYENGVPPPARHGRAIVEPDHKAWEGQKPISIVGSTGTIGTQDKCGKSRE
KLSTPSPSVITQAHPQPQALNHNAADDSTKDSPDGK
>Sgl43198 E3_activity/RING/RING 16.7 5.7
MFLMKLNKVYSGVRTNILMMNPLPNLPKAYSILIQEQKHKELSKMSENSSSQMIACLADK
RKFDNRGPYNGNHRNQPFNRNTNGGSTYNSSIVPKNVYKRPFCDFCKYHGHTKDTCYKLN
GYPPRDGKPLFKKYAAMAHTDDNDGDNNAQADGQHNSGSCSIPPSFNHEQYQQLLALIQP
SNISSNDSAALVAGKFCLFSYNSNSWVIDSGATDHMCSNLELFTSYAKIDDLNSFITVPD
GARVQVTHKGVIDFGSGIILRNVLFVPDFKFNLISVPQLCSDNICSVNFTPTSCIIQGPS
MTKPLMLGKLHSGLYFLQDHLSKTPSVSNSLPISTAANHTSTCLSAVDESKLLHLRMGHL
PFKKLSYIAPHLKNVVFHERYFPFHHLPHSSPSPFFLPISSPPPTFDDYPIPDALNISST
NSDNTLATSSSSSTIVDLSPLLSVPQPSASPLPEPVSTVRRSSRPTKLPSYLDDYIHPPL
PSSNTHIASATSFTPHCPAVVLLGYGIAWDFSFQCLILHNSATSLTCNHVSCNSCIQKSM
KTGVSCPVCKVPYQRRDLEYHEDGAPEQFKIMIPKSPAYFMVHSFSL
>Sgl43254 E3_adaptor/Cullin_RING/DCX/DWD 107.1 4.3
MAEVQKSEEATISFKNLFNREYHGHKKKVHSVAWNCTGTKLASGSVDQTARVWQIEPHSH
GKAKDIELKGHTDSVDQLCWDPKHADLLATASGDKTVRLWDARNGKCSQQAELSGENINI
TYKPDGTHIAVGNRDDELTILDVRKFKPIHRRKFNYEVNEIAWDMTGDKFFLTTGNGTVE
VLAYPSLKALDTLTAHTAGCYCIAIDPLGRYFAVGSADSLVSLWDIKEMLCVRTFVKLEW
PVRTLSFNHTGEYIASASEDLFIDIANVETGRSVHQIPCRAAMNSVEWNPKSNLLAYAGD
DKNKYQTDEGVFRIFGFQTA
>Sgl43366 E3_adaptor/Cullin_RING/BCR/BTB 18.7 0.0
MKFMKLGSKPDTFQSEDKNVRYVATELATDIVIKVGDVKFYLHKFPLLSKSSWLQQLVSN
EQSNDEVIITDIPGGTAAFEICAKFCYGMVVTLNAHNVVAARCAAEYLGMHETMEKGNLA
YKIDVFLHSVIFRSWKDSIIVLHSTKSMLPWSEDLKLISQCVEFIASKAVTDTSKVDWSY
TYNRKKLPEETGTDPNWTGIRNKVVPNDWWVEDLCDLEVDLYKRVIVSINGKGIVCGEVI
GEALKAYTDRHFPSLIKGVNRSSDLTNYRSTVDTIIFLLPDEKGCVTCSFLLKLLKASIL
GDSAEVVKKELIKKIGHQLEQASVSELLIRAPEGETLMYDVDIVLNIVHEFLIRDQSSEI
ETLEAGEEAHEFKDPGILSEASKLMVAKLIDGYLAEISRDRNLPVSKFVELAEMVSSISR
PGHDGLYRAIDMYLKEHPEISKSDRKRICKFMDCKKLSVDACMHAVQNERLPMRVIVQVL
FFEQVRAAATSGTSTPDLPKSIRDLNNGSQRSSKSTPIADEDWDTVATAEELKALKSELA
TLKLERKKSEKVVEGRHSIDKAAFHKMKGVVMTKKIFSKLLSSKSANTHGGDTSGSDSSE
TPSSANPEDVKSTPSMNRRVSVS
>Sgl43381 E3_adaptor/Cullin_RING/DCX/DWD 64.4 11.2
MTAVAPPVVGQELSNPPTDGITNLRFSNHSDHLLVSSWDKTVRLYDASANVLRGEFKHGG
PVLDCCFHDDSSGFSASGDSTVRRLVFNQGKEDILGKHDAHVRCVEYSYTTGQVISGSWD
KTLKCWDPRGAGGPERTLVGTYIQPERVYSMSLVGHRVVVATAGRHVNVYDLRNMSQPEQ
RRESSLKYQTRCVRCYPNGTGYALSSVEGRVAMEFFDLSEAGQSKKYAFKCHRKSEAGRD
IVYPVNAIAFHPIYGTFATGGCDGIVNVWDGNNKKRLYQYAKYPTSISALSFSRDGHLLA
VASSYTFEEGNKPHEPDAIFVRSVNEVEVKPKPKVYANPPA
>Sgl43677 UBD/UBC-like/UBD_UBC 109.1 0.0
MKLCPREVEKLALHNDGFLAQKRLASGLRLNYTEAVALIATQVVVHSEKFYNFRSSVFID
FEFCSCWKQECGGTDGHWKEASWKRPSETPYDGGVFQLAFAVPEQYPLQPPQVRFLTKIF
HPNVHFKTGEVCLDILKNAWSPAWTLQSVCRAIIALMAHPEPDSPLNCDSGNLLRSGDLR
GFQSMAKMYTRLAAMPKKG
>Sgl43709 E3_activity/RING/RING 28.1 8.1
MKISESDSVGGCVATEAFRLLGYHRKNWILYHRRFVDVDLHATRKEVQCPICLGIIKKTR
TVMECLHRFCRECIDKSMRMGNNECPACRTHCASRRSLRDDQRFDQLIVVLYPDIRKFEE
EEVAFYDEDEARNKQIQESITQVLIKQSEALGKKRSSNKDAAGASVTRSQR
>Sgl43828 E3_adaptor/Cullin_RING/DCX/DWD 107.1 4.3
MAEVQKSEEATISFKNLFNREYHGHKKKVHSVAWNCTGTKLASGSVDQTARVWQIEPHSH
GKAKDIELKGHTDSVDQLCWDPKHADLLATASGDKTVRLWDARNGKCSQQAELSGENINI
TYKPDGTHIAVGNRDDELTILDVRKFKPIHRRKFNYEVNEIAWDMTGDKFFLTTGNGTVE
VLAYPSLKALDTLTAHTAGCYCIAIDPLGRYFAVGSADSLVSLWDIKEMLCVRTFVKLEW
PVRTLSFNHTGEYIASASEDLFIDIANVETGRSVHQIPCRAAMNSVEWNPKSNLLAYAGD
DKNKYQTDEGVFRIFGFQTA
>Sgl43894 E3_adaptor/Cullin_RING/DCX/DWD 45.8 20.7
MIYGGRSFVSSSPAFSNDTKRLLICTGNTVSVFSTSTGMQITELEGHGSLVTSVVVVPSS
SKVLCYCWTSSLDGTIRYWDFSVPELIKTINIRLPIFSMVIPSVLSKQDDVGGKPASVFA
YISVENMSDPDNKPKHLHGQIRKCNLTKSKLVSSVILKETAQPQFLTISPSGKLFAIQTK
RTLHIWKVPDDDSERALVKKMKLQHTKSFTTFAFHPNDSVVAAADVSGRILVWRGFSMRT
LLESNEQAKGKLTKYEDDKAGVRGENDAESCTTWHWHSSEVKFLAFSSDGVYLYSGGNEG
VLVLWQLDTGKKKFLPRIGSPLLYFVHSPDPTLSLISCSDNQIHILKMSSLEILKSITGI
KLPCSSPEIWSGLSGGFSFDCSAGIVALPTDNYRIQFYSLFDDTEISEVQICERNHQPSD
DIMVVVSLVALSHDGSLMSTVETRLAEDGVGGLVCLKFWATESRKDYKLSTIVYEPHRDA
AISAIAFRPGWKMVVSSSYGGDFKIWVQSDSTQSKSGIHTSGWVCHSVGAYKEKSMTAAT
FSADGSILAVAAETVITLWDPDRNYLVAVIGETYTPIVNLAFVGNSEYIVSTSHGTRPQL
SLWCLSKLSRTWSYDFHVEAVASMEDDTFFAVLAVIPESSISVESHGGSISSGDGIILLF
DTNSPTPIATWLVREAKGGGLAFLQGNKLSSLEDTNSSGRPAILLAYVSRDHEYVVFDPL
SKEQHKLNMNFKKGAMDSQEAERSGYASIYGELPHFDPKKTMQARILPSERPWETIFSGP
SHTLPPLTKLCSAFLESLLEKRTAATG
>Sgl43929 E3_adaptor/Cullin_RING/DCX/DWD 28 0.1
MLTNFETKSNRVKGLSFHSKRPWILASLHSGVIQLWDYRMGTLIDRFDEHDGPVRGVHFH
KSQPLLFVSGGILDRFYKRSDVPGLNWQYPTLLIDQNSKLGFAHFP
>Sgl43935 E3_adaptor/Cullin_RING/DCX/DWD 96.2 4.4
MKSKTSKRKPSSMYNNKVKKNSQNSDSKRRRKFDAEDEELNGFDSEVSDSGDDFFADENG
GELKDGDSDSDSEEDELERETAEEKRRRLAWDLVHKVRKGEQELKDEEDDDDEEEDDRED
KEGNRDSLVAKILQQEQLEESGRVRRLIASKLQKPEDVEEPQLLLKHRQSVTAVALSEDD
RIGFSASKDGYIAHWDVEVGKAEKYLWPSDDVLKLHKLKNRTANSKSSRGRTPKHSKSVL
ALAVSSDGRFLATGGLDRHVHLWDIRTREHVMAFSGFRGPVSCLAFRQGTSEIFAGSFDR
TLGVWSAENLNKITTLYGHQSEVLSMDCLRKERVLTVGRDRTMQLYKVPEEARLVYRAPA
SSLECCCFVGNDEFLSGSDDGSIELWSALRKKPVSIVRNAHTIPSLKKQVDLADNGRMAN
GHIDGTEYKADNPCTTAQSWVSSITVCRNSDLAASGAGNGFVRLWTINSDNRGIEPLYDV
PLVGYVNSLAIAKSGKFLVAGVGQEPRLGRWDRIPTARNGVALQSFKLTS
>Sgl43938 E3_adaptor/Cullin_RING/DCX/DWD 30.4 0.1
MLTNFETKSNRVKGLSFHSKRPWILASLHSGVIHLWDYRMGTLIDRFDEHDGPVRGVHFH
KSQPLFVSGGILDRFYKRSDVPGLNWQYPTLLIDQNSKLGFAHIP
>Sgl44166 DUB/USP 360.6 0.0
MNASWFIHRNRNLKGLQICEAALNLYFDEVQPILCGLIVDHRWWQNWLDYVNQDGMYGVN
DEPSPRSLDPADAWLSRRPSSIDNKYLIFESVSSDSNAAELHDTLVEGRDYILLPEEVWH
QLYNWYGGGPTLARKVINFGISQMELAVEVYPLRIQLFLTPKGDRSTIRISKKETIRELY
KRVCEIFNLDSEKIRIYDYYGKKKHALPTDLDKTLDDANIQMNQEILVEVLNNATSSIKS
NGTMRKQLNSFLLEPSKSGLSIAGGLSATKDVSTNCNLETSPGQNQVSPHRELNVVQETS
GVTTRGATAGLTGLVNLGNTCFMNSAIQCLVHTPEFARYFREDYRAEINRRNPMGMVGEL
ALAFGELLRKLWAPGRTPIAPKPFKAKLSRFAPQFSGYNQHDSQELLAFLLDGLHEDLNR
VKDKPYILSRDADGRPDEEVADEYWQNHKARNDSIIVDVCQGQYKSTLVCPVCAKVSVTF
DPFMYLSLPLQSTATRPLTVTIFSSDGRLLPNICTVTVPKQGRCRDLIQALSAACSLRPN
EKLLLAEIQNHLIHRFFEDPLTPLSNIKDEDHLAAYRIPLPAKGIIFLQLIHRLEDKGTV
NAQGVKGWKPYGTPLVSPIAYDDITTRGDVQTMVRTMLSPLLKEREKTSLSENDITPAVE
NSCDNFIKPVDSSESATWTERKNTETCGLEKLPLQLVDENNVCIDLSVGDEKLVNIPSSS
KSLLVFINWSKVLMEKYDTSYLENLPDVCKVGLPAKKARTEPLSLYSCLEAFLREEPLVS
EPDMWKCPQCEERRQASKKLDLWRLPNVLVIHLKRFSYNRSLKHKLDTFVNFPIYDLDLL
KYIANKNNSDPQLYELYALINHYGSMGSGHYTAHIKLIDENKWYSFDDNQISAINEEEVK
TNAAYVLFYRRKKVDA
>Sgl44201 E3_adaptor/Cullin_RING/DCX/DWD 20.9 0.4
MAEWNPKKDLLALVTDDSKIILHHFNWQRLWTISPGKRIASLCWRPHGKSVAVGLEDGTI
SLHDVENGKLLRSVKSHNVIVVCLNWVEDDGHGQLTRACIFLFYFLFLFISILLSTFVDL
LVKRH
>Sgl44438 E3_adaptor/Cullin_RING/DCX/DWD 58.7 1.2
MQLTRMTGVGKNDPTKTAWGTTRISIVNSMKPKATSPMTATVSDHQEAIHKKIFQSLCGH
TTPVESLAFDSAEVLVLGGASSGTVKLWDLEEAKSEFVYVLHFIYPPFVLLIKKLCNSLK
KVVRTLTGHRSNCTSVEFHPFGEFFASGSADTDLKIWDIRKKGCIHTYKGHTGGINTIKF
TPDGRWVVSGGFLFHFVRNHLR
>Sgl44510 E1 384.1 0.1
MGEPKIKYDRQLRIWGDQGQAALEKASVCLLNCGPTGSETLKNLVLGGIGSITVVDGSKV
EVGDLGNNFMVDESSLGESKAKCVCAFLQELNDAVKAKFIVEFPEKLIESNPSFFSQFTL
VIATQLVEEKMVRLDKICREANVKLIFARSYGLTGLVRVSVKEHSVIESKPDHFLDDLRL
NNPWAELKSFVESIDINVPDPVAHKHIPYVVILVKMAEEWAQSHSNTLPSTGEEKKAFKD
LLKSRMIGFDEDNYKEAVDASFKLFAPRGISPNLKWILQDSCAEIDSNSTDFWVMVAALK
EFINHEGAGEVPLEGSIPDMTSSTEHYVNLQKVYQAKAEADFLAMENHVQNLLKDIGRDP
SSLSKITIKIFCKNARKLKVCRYQTVEEEFNSPNVSELQKYFTDEEYSIAVGFYILLRAV
DRFAANYNCFPGQFDGEMDEDISRLKTQTVNLLNDLGCNSSVMTEDLINEICRFGASELH
AVATFIGGIASQEVIKLITKQFIPMTGTFVFNGIDQKSQLLVL
>Sgl44624 E3_adaptor/Cullin_RING/DCX/DWD 60.1 2.7
MSRPLSSSPNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNKLARSPSP
RGSNCSIESRESRFSDNDRNNFLDKPSSSHFPFCPTILPVPVQGPSTGQRASRALDLAPA
NVSTIPVVGDDDGSDDEGRIEDARTPEDCPILETAYNYYKANIKKYREYCDFGEGYKLGF
PKPTTVVELKYINLNNRGMEINLKSLPFDIDFHPSNSLVATGLINGYLLLHLYAADAEPQ
RLLKVRAHKNSCRAARFIHEGNAIVTGSPDCSILATDVETGSKIAHLQNAHTAPINRIMN
LTEATIASGDDAGCVKVWDTRQQSCCNTFEVHEEYISDMTFAPDSMKLLATSGDGTLSVC
SLRSNKVHAQSEFCEDEPLSVLIMKNGRKVVCGTQTGTLLLYSWGLFKDCSDRFVDLSPN
PVDALLKYDEDRIVTGSYNGLISLVGILPNQIIQPIAEHSEYPVERLAFSHDKKLLGSIS
HDNILKLWDMDGLLQGSNTLTRNDTTALDNDSNSDGMDVDSDLPKASKGTKRKNNGQASS
SSFGGFFADL
>Sgl44899 DUB/JAMM 33.2 2.8
MDRLTRMFAGAGGALGHPPPDSPTLDTSEQVYISSLALLKMLKHGRAGVPMEVMGLMLGE
FVDEYTVRVVDVFAMPQSGTGVSVEAVDHVFQTNMLDMLKQTGRPEMVVGWYHSHPGFGC
WLSGVDINTQQSFEALNQRAVAVVVDPIQSVKGKVVIDAFRLINPQSMMLGQEPRQTTSN
LGHLNKPSIQALIHGLNRHYYSIAINYRKNELEEMMLLNLHKKKWTDGLSLKRFDIHSKT
NEQTVQVSAVYINCSISELA
>Sgl44921 E3_adaptor/Cullin_RING/BCR/BTB 19.5 0.0
MACVKLGSKSDAFQRNGQAWFCTTGLPSDIIVEVDEMSFHLHKFPLLSRSCVLERLIAES
DDGEVGSIISISDLPGGAKIFELVAKFCYGVKLELTASNVVYLRCAAEHLEMTEEYGEGN
LIFQTETFFTQAVLKNWKESLKALQTCDDILPCADELHITKRCIESLATKASTDPNLFGW
PVVERGGPMQSPGGSVLWNGISTGARPKNSTSDWWYDDVSTLSFRLYKRLISAMESRGLK
PEIVSGAIAYYARKFLPGLNRRQGDSSSRLGPHSMSSPPSEEDQKLLVEEIDKLLPVQKG
LVSAKFLFGLLRTAMILRADSNCISSLEKRVGMQLDQANLEDLLMPNFSYSMETLYNVDC
VQRILDHFLMMDQANGDASPCSIDDGQLIGSPSLTPITMVAKLIDGYLAEVAPDINLKLP
NFQALAAAVPEYGRPLDDGLYRAIDIYLKSHPWTSESEREQLCRLMDCQKLSLEACTHAA
QNERLPLRIVVQVLFFEQLQLRNSIAGCFLVSENLEGSRQLRSGVVGSNEGAGWATAVRE
NQVLKVGMDNMRMRVSELEMECSNMRSEIEKLGRVKGPSTWGNVSRKLGLGLKMKSQMCS
AEEGSVSNQSVVSGKGEKVKEKCAKTKKKL
>Sgl44929 E3_adaptor/Cullin_RING/Cullin 633 4.4
MSPPNNNKRPSSSSSSSSSAINNNSNINLNNNHSNNNNNNNNNNNNLSSSSSYFPPMKKL
KPQNSSLDSKNGIHSSSLTDDDVVVNHGASMIVDDDLKPDAVVSPSSNSRPITAGVTANL
SRKKATPPNPSTKKLVIKLVKAKPTLPPNFEEDTWATLKSAINAIFLKQPDSCDLEKLYQ
AVNDLCLHKMGGSLYQRIEKECEAHVSTVLYSLVGQSPDLVVFLSLVEKCWQDLCDQMLM
IRGIALYLDRTYVKQNPSVKSLWDMGLQLFRKHLSLCPEVEHKTVTGLLRMIERERLGEA
VDRTLLNHLLKMFTALGIYQDSFEKPFLACTEEFYAAEGAKYMQQSDVPDYLKHVEIRLH
EEQERCLLYLDVSTRKPLITTAEKQLLERHISAILDKGFMMLMDGSRIDDLQRMYNLFSR
VDALESLRQALSSYIRKAGQATVMDEEKDKDMVSCLLEFKAALDKIWEESFSKNESFGNT
IKDSFEYLINLRQNRPAELIAKFLDEKLRAGNKGTSEEELEGTLDKVLVLFRFIQGKDVF
EAFYKKDLAKRLLLGKSASIDAEKSMISKLKTECGSQFTNKLEGMFKDIELSKEINESFK
QSSQARTKLPSGIEMSVHVLTTGYWPTYPPMDVRLPHELNVYQDIFKEFYLSKYSGRRLM
WQNSLGHCVLKADFPKGKKELAVSLFQAVVLMLFNDAEKLSFQDIKDATGIEDKELRRTL
QSLACGKVRVLQKNPKSRDVEDDDSFVFNDGFAAPLYRIKVNAIQMKETVEENTSTTERV
FQDRQYQVDAAIVRIMKTRKVLSHTLLITELFQQLKFPIKPADLKKRIESLIDREYLERD
KNNPQIYNYLA
>Sgl45043 E3_adaptor/Cullin_RING/BCR/BTB 19.5 0.0
MACVKLGSKSDAFQRNGQAWFCTTGLPSDIIVEVDEMSFHLHKFPLLSRSCVLERLIAES
DDGEVGSIISISDLPGGAKIFELVAKFCYGVKLELTASNVVYLRCAAEHLEMTEEYGEGN
LIFQTETFFTQAVLKNWKESLKALQTCDDILPCADELHITKRCIESLATKASTDPNLFGW
PVVERGGPMQSPGGSVLWNGISTGARPKNSTSDWWYDDVSTLSFRLYKRLISAMESRGLK
PEIVSGAIAYYARKFLPGLNRRQGDSSSRLGPHSMSSPPSEEDQKLLVEEIDKLLPVQKG
LVSAKFLFGLLRTAMILRADSNCISSLEKRVGMQLDQANLEDLLMPNFSYSMETLYNVDC
VQRILDHFLMMDQANGDASPCSIDDGQLIGSPSLTPITMVAKLIDGYLAEVAPDINLKLP
NFQALAAAVPEYGRPLDDGLYRAIDIYLKSHPWTSESEREQLCRLMDCQKLSLEACTHAA
QNERLPLRIVVQVLFFEQLQLRNSIAGCFLVSENLEGSRQLRSGVVGSNEGAGWATAVRE
NQVLKVGMDNMRMRVSELEMECSNMRSEIEKLGRVKGPSTWGNVSRKLGLGLKMKSQMCS
AEEGSVSNQSVVSGKGEKVKEKCAKTKKKL
>Sgl45062 DUB/JAMM 32.8 2.8
MDRLTRMFAGAGGALGHPPPDSPTLDTSEQVYISSLALLKMLKHGRAGVPMEVMGLMLGE
FVDEYTVRVVDVFAMPQSGTGVSVEAVDHVFQTNMLDMLKQTGRPEMVVGWYHSHPGFGC
WLSGVDINTQQSFEALNQRAVAVVVDPIQSVKGKVVIDAFRLINPQSMMLGQEPRQTTSN
LGHLNKPSIQALIHGLNRHYYSIAINYRKNELEEMMLLNLHKKKWTDGLSLKRFDIHSKT
NEQTVQEMLGLAVKYNKAVQEEDELPPEKLAIANVGRQDAKKHLEEHVSNLMSANIVQTL
GTMLDTVVF
>Sgl45088 E3_adaptor/Cullin_RING/DCX/DWD 21.7 1.4
MELQNLGVAICGKWIKRPEKNVNLVVLGKSYKSSSAKSKVEIFSFDPNNNCLSPTPVSEV
EIEDGEPISIAVHPNGEQIICTTTSGDCKLFDLRVIENSIKLSAREAPSLKGVGRQTCVA
FSIDGCKLGLGGENGRLRIIEWPSMRIIIDEADAHKSFRDMDFSLDSEFLASTSTDGAAR
VWNVNEGVPVATLKRNPDEKIELCCFSKDGTKPFLFCTIQRAKFKPTTAVWDMSTWKRIG
FKVLLAKPASVMSTSPDGKYIGMASKDGDFCIVEVKTMRINHWSKRLYPNTFIETLEFCP
TERVVLTTTKEMGFKITKLTVPADWKDWQIYGILVALLLVSAVAFYIFYLYSDSFWQAPD
SYQNFPHYNTIRSDPQSSEDPFGPLDL
>Sgl45215 E3_adaptor/Cullin_RING/SCF/F-box 17.4 0.2
MSTIEEPRNWLELPHDVILLILMKLECSHILETVQFVCKLWYSCCKDPSIWCTIVMNTSD
EFLCVGDDRWNKMLYNAVDRSCGGLIKLDLEGFSSDKSDNLITCVVQQSSQLKHFRLACC
YEISGHALIEALGKLPSLEVVELTLCSIASARTIDIINCCPSVKTFKLNKLPYMNRTCDD
EALAIAASMPGLIHLQLIGNIMTNAGLVAILDNCPQLQSLDLRACLHLHFAGNLAKRCSE
QIKDLRRPSDSTYDYNYPTTPRDYWDDAIYVDGPHDVDYMSDSDPMWL
>Sgl45218 E3_activity/RING/U-box 24.5 0.7
MADTLYLEKMGRELKCPICLSLLNSAASLTCNHVFCNSCIQKSMKSGASCPVCKVPYQRR
EIRPAPHMDNLVNIYKSMEGASGVTLHVTQNEPTTKMADAEKHAGHRLDITENDGKNQEL
VECQRTEGTSSIASKLKPKRSGRNRGKSSFAMNKRVQMPESPTSETPIREMKDGLSQSRV
INTIMNKCSTFSSENPIPIENERPNLSPFFWLREEVERTSQQTDGEQLTLSCTPEKGPSF
SDLKDSDDELPLDISSKEQRNKCNADVFDSEMFEWTQRECSPELCSSPFKQQDEEPDCDT
MGEPMEAASRDAVADSKLITENLTNVSLQENTSTMDNKLLKDLFSKRKGQDSRNGPKVPY
KKGGKKIKQSKKKCRKNNMEIDEAFENPKTPDELMQCKGFDAELVLGDAEAAGTSKTGQN
QSFDVSIMNEADNHVVPESPVASRSKRGTNKNKKLENIKRRLDSIKASNEGQLVKRKKQK
KNLAQPVVNTEKSIPSNEMLLEKPCRVRKKLSSCSTSNKPNEICQLAAVKQKYSLDKNAR
GKNVGGEAAAQVAVASAQAKSNNDNSGNSLKRGKVHGNKDIPSLRKCDTVSVKCAFCHST
EETEATGEMAHYSEGRPVAANHSGGSVIHSHKYCTEWAPNVYFEDNMVVNLEEELTRSRR
IKCSLCGVKGAALGCYEKSCRKSFHVPCAKMLRECRWDTDHFVILCPLHAPSKLPSELPA
PQVRKRNCNFEGKIPCQKPPVAARQATSTAKWNCVRPSEKVVLCCSALATTEKDAVSKLA
KSSGAVVFKNWNPSVTHVIASTDENGACRRTLKVLMGILEGKWILSIRWIQACKEAMRLV
EEAPYEINCDIHGVRNGPRLGRLRLLNEQPKLFSGFNFYFMGDFEPSYKGYLQDLVTAAG
GTVLHRKPIAQTQGVNVPSSSASSTVIVYSIELPANCDIDKDVVLDRRHFDAEALAMSCG
AKLANNSWVLNCIAGHKLLDH
>Sgl45234 E3_adaptor/Cullin_RING/SCF/F-box 21 0.1
MSTIEEPRNWLELPHDVILLVLMKLDCSQILENVQFVCKLWYNCCKDPSIWRTIVMIVGE
FEMVGVRWKNMLYNAVDRSYGGLIKLNIEGFGSDDDITYVAHRSSQLKHLRLARCLKISG
RALIEAFGKLPSLEVVELTLCSFASKQTVAAINCCPSSIKTFKLNKRASSYYTLISDDEA
LAIAANMPGLIHLQLIGNTMTNAGLEAILNNCSQLQSLDLRACFNIRFDGNVAKRCSEQI
KDLRGPFDSTYDYNYPTTPTVYYSSDDDLLWDDYMISSHDLDYMSDYSDNDPMWYY
>Sgl45235 E3_activity/RING/U-box 24.6 0.8
MADTLYLEKMGRELKCPICLSLLNSAASLTCNHVFCNSCIQKSMKSGASCPVCKVPYQRR
EIRPAPHMDNLVNIYKSMEGASGVTLHVTQNEPTTKMADAEKHASHRLDITENDGKNQEL
VECQRTEGTSSIASKLKPKRSGRNRGKSSFAMNKRVQMPESPTSETPIREMKDGLSQSRV
INTIMNKCSTFSSENPIPIQNERPNLSPFFWLREEVERTSQQTDGEQLTLSCTPEKGPSF
SDLKDSDDELPLDISSKEQRNKCNADVFDSEMFEWTQRECSPELCSSPFKQQDEEQDCDT
MGEPMEAASRDAVADSKLITENLTNVSLQENTSTMDNKLLKDLFSKRKAQDSRNGPKVPY
KKGGKKIKQSKKKCRKNNMEIDEAFENPKTPDELMQCKGFDAELVLGDAEAAGTSKTGQN
QSFDVSIMNEADNHVVPESPVASRSKRGTDNNKKLENIRRRLDSIKASNEGQLVKRKKQK
KNLAQPVVNTEESIPSNEMLLEKPCRVGKKLSSCSTSNKPNEICQLASVKQKYSLDKNSR
GKNVDGGEAAAQVAVASAQAKSNNDNSGNSLKRGKVHGNKDIPSLRKCDTVSVKCAFCHS
TEETEATGEMAHYSEGRPVAANHSGGSVIHSHKYCTEWAPNVYFEDNMVVNLEEELTRSR
RIKCSLCGVKGAALGCYEKSCRKSFHVPCAKMLRECRWDTDHFVILCPLHAPSKLPSELP
APQVRKRNRNFEGKIPCQKPPVAARQTTSTAKWNCVRPSEKVVLCCSALATTEKDAVSKL
AKSSGAVVFKNWNPSVTHVIASTDENGACRRTLKVLMGILEGKWILSIRWIQACKEAMRL
VEEAPYEINCDIHGVRNGPRLGRLRLLNEQPKLFSGFNFYFMGDFEPSYKGYLQDLVTAA
GGTVLHRKPIAQTQGVNVPSSSASSTVIVYSIELPANCDIDKDVVLDRRHSDAEALAMSC
GAKLANNSWVLNCIAGHKLLDH
>Sgl45239 E3_adaptor/Cullin_RING/DCX/DWD 90.5 8.0
MRPILMKGHERPLTFLKYNRDGDLLFSCAKDHNPTVWFADNGERLGTYRGHNGAVWSCDV
SWDSSRLLTGSADTTVKLWDVKKGEQLFTFNFDSPARSVDFSVGDKLAVMTTDPFMEKTS
AIHIKRIAEDIEDQDKESALVIRGPSGRINRAVWGPLNKTIISCGEDAIIRVWDPVTGQE
IMSTKDHESGHKQAITSLSMSADKSHFLTGALDKSAKLWDTRTLTLIKTYGTERPVNAVT
MSPLLDHVVLGGGQEASSVTTTDHRAGKFEAKFYDKILQEEIGGVKGHFGPINALAFNPD
GKSFASGGEDGYVRLHHFDPDYFNIKL
>Sgl45243 E3_adaptor/Cullin_RING/SCF/F-box 20.7 0.1
MESEFTNAETLAMASSDMEVTPSSSLSLPSAIEEPRNWLELPRDVTLLILMKLNTFEILE
SAQFVCKLWYNCCKDPSMWRTIVMHNLDEHESVEKHQKMLYNAVDRSSGGLIKLDIEGFG
CDDLIIYIAQRSNQLKLLRLACCYAVSADALIEAFGKLPSLEEVELTLCSFTAAQTINII
HCCPSLKTFKLNEQGSRNPTMACDDEALAIAESMPGLNHLQLIGNSMTNVGLKAILDNCP
HLQSLDMRACFHIHLAGSLAKRCAEQIKDLRCPYDSTEDYSYLTTDYDSDFDEIYPDDYD
DLDFVSDDDYYEFSDDNDGHLYADVYDF
>Sgl45369 E3_adaptor/Cullin_RING/SCF/F-box 13 0.0
MKNNVKRMRIKSESKEEDRLSELPEEIIIDIISLLPIRSAAATSVLSRRWRNLWTHIHSI
DVRLSEFINTPVHARYNLNIIDDIVLKKLTSTSIERFTISGSFTNDNLDSWFSKICCRNV
KEIKIDCDSRGVPPILPTLVFRTVSLVVLDIGEGGNFFLPSNWSVNLINLPKLKKLRLIN
YRRYIKFVEKLVSSCPLLEELFIKTVYLGPLRCNKVFKLSCHNLKTLELENYKDNSVQGH
GVEIGVYTTKFVIDAPKLEYFSARAYRFEDLSFKFVGNPTALLHRTRLMRTYNIWNSLVW
VNPSSNFFKTTSLELDCIRVRPLRAFPNLTRLELRWPLDNDWGVLVRFLQYCPALEVLML
NIVSVYNVKNLRWIPSSRSSALETPNPPPCFLQMCLKKIELKIERRIRFKEQLINMVRYL
LRNFRVLEQFTFRADKQDDGRIKDKSHIQRDERKVCEDMFSLAKRSSRCQINFVGECHKA
SSNNARIVQES
>Sgl45372 E3_adaptor/Cullin_RING/SCF/F-box 12.8 0.0
MKNNVKRMRIKSESKEEDRLSELPEEIIIDIISLLPIRSAAATSVLSRRWRDLWTQIHSI
DVRQSEFNNSPNIDIKYYGFFTIIEDIVLEKVTSTTIERFSVSLGASPTYHLHSWFDKIC
CRNVKEIKVECKSRVVEPLTLTVSFLVLQTVSLVVLDIGEGFDFHLPSDDDYVDRVISII
NLPRLKKLRYSNFAGNAKFLENLVSSCPLLEELFIKMVYLDPQNKVFKLSCHNLKVLELE
YDKNKYIQRREGVYTTKFVIDAPKLEYFSARAYRFEDLSFKFVGNPTALLHRARLMRTYN
IWNSLVWVNPSSNFFKTTSLELDCIRVRPLRAFPNLTRLELRWPLDNDWSVLIRFLRYCP
ALDVLMLNIVSVYNVKNLRWTPSSRSSAFETPANPPPCLQKRLKKIELKIERRIHYREQL
INMVRYLLRNFFVLEQFTFRIDNRDDCKIKDKSRFQSYERKVCEEMFSLPERSSRCQINF
VGEYHKASTNKARIVQGS
>Sgl45373 E3_adaptor/Cullin_RING/SCF/F-box 13.3 0.1
MKNCVKRKRSCNIITLKSESKEDRLSELPDEIIIEIISLLPIRSAAATSVLSRRWRDLWT
QIHSIDVRQSEFNNSPNIDIKYYCFFNIIEDIVLEKVTSTTIERFSVSLGASPTYHLHSW
LNKICCRNVKEIKVECKSRVVEPFTLTVSNVVLQTVSLVVLDIGEGFDFYYFPSDDYVDR
VISIINLPRLKKLRYSNFAGNAKFLENLVSSCPLLEDLFIKVVYLDPQNKVFKLSCHNLK
VLELEYDKNKYIQRREGVYTTKFVIDAPKLEYFSARAYRFEDLSFKFVGNPTALLHRARL
MRTYNIWNSLVWVNPSSNFFKTTSLELDCIRVRPLRAFPNLTRLELRWPLDNDWSVLIRF
LRYCPALDVLMLNIVSVYNVKNLRWTPSSRSSAFETPANPPPCLQTRLKKIELKIERRIH
YREQLINMVRYLLRNFFVLEQFTFRIDNRDDCKIKDKSRFQSYERKVCEEMFSLPERSSR
CQINFVGEYHKASTNKARTVQGS
>Sgl45396 E3_activity/RING/RING 30.5 3.2
MGNAIHMNCSHDTLATSSSKDSSSPPKHIITSYITSVSYHRVVYHNNNTTSDGRRYTRFV
SRTEQPNPNVYRCSKPLNPLCVFCRKDIFALLLNSEYLRKEAHDELKRFSHEVRTKVKSM
RSDINKNNKHAKDKDKDNDNAAIVIYHQIHKHGLPDRVIDQEEYMRLLAKGVVFDEEVVP
IARPASELAIRGLQRVVLSNDKLVSNDEDNNMCSICLQELVIMKKEENYNDKDDNEELIN
KSSVVRLLCKHMFHEGCVVKWLRRSHVCPNCRFKLPLAS
>Sgl45422 E3_adaptor/Cullin_RING/SCF/F-box 16.6 0.0
MRKKNQISWNNSLPLELQREILARLPVKTLLQFRCVSKSWCSLIDCPYFKSLHFNRYNNN
NNNSTNNPKFIAIHEFHHNYITTLRRSDSFRRIGAEIASFDRNIHHLSLRQICKGVFLIR
HNLMMKLWNPSIRKCLIIPYSPILVPDYFVRYKLGFAPSSNDYKLVAIKPDLGITAIYSV
NDHRWRGLPAALQFDYKNRVVVSGGAMYWVISDQPEATPAIGEFDFESEELRVVQPPDAV
KGSIVWFIFRYGESIAVFTMSHENNCIWGMEKKKNGGRKDDVCNWRQWFLGKPNLNPKAY
SLFLCIKTEILYVQKTNTFVMVDKSSTKERVMSYNLINHRIKHLAKSLYSKISFNTYVES
LVLHKGVEGQNLASFP
>Sgl45436 E3_adaptor/Cullin_RING/DCX/DWD 64.4 12.0
MFLHTPPLAVSFANTIKNAHILGVTDEEGYVNLINTHSKLDPSATNQENAAKVVVSSWVV
HDNSVYDICWIKEDMNVLTASADHSIKLWDVEQKKCHGTLRGHVGSVKSISCHPTNCYLV
VSGSRDGFFMLWDLRCSPQRGRHWMMQTEQVNGAHASVKRKRFTRKKAASNPSMMVTSVL
YLKDDVSIVTEGVVDSVVKLCDTRNLRAPAVQASPLQETTTETVSVLASMGDYMELPAYP
KIEMESCFLHLVPIIEYIYIMFSNSKRVQSAPSLEVKLDHFISSPDASHILSGSADGNAY
IWQVDRPHQDPISLTRHEKKVTAVDWYVTNIYEVRFWDIQNRNYLLPRISTTRHKRVVKA
PRTECIEEKEPSPQRESPCNSSGKEAGSVLFNLL
>Sgl45476 E3_adaptor/Cullin_RING/SCF/F-box 16.6 0.0
MRKKNQISWNNSLPLELQREILARLPVKTLLQFRCVSKSWCSLIDCPYFKSLHFNRYNNN
NNNSTNNPKFIAIHEFHHNYITTLRRSDSFRRIGAEIASFDRNIHHLSLRQICKGVFLIR
HNLMMKLWNPSIRKCLIIPYSPILVPDYFVRYKLGFAPSSNDYKLVAIKPDLGITAIYSV
NDHRWRGLPAALQFDYKNRVVVSGGAMYWVISDQPEATPAIGEFDFETEELRLVQPPDAV
KGSIVWFIFRYGESIAVFTMSHENNCIWGMEKKKNGGRKDDACNWRQWFLGKPNLNPKAC
SLFLCIKTEILYVQKTNTFVMVDKSSTKERVMSYNLINHRIKHLAKSLYSKISFNTYVES
LVLHKGVEGQNLASFP
>Sgl45490 UBD/UBC-like/UBD_UBC 111.7 0.0
MKLCPREVEKLALHNAGFLAQKRLASGLRLNYTEAVALIATQVVVHSEKFYNFRSSVFID
FEFCSCWKQECGGTDGHWKEASWKGPSETPYDGGVFQLAFAVPEQYPLQPPQVRFLTKIF
HPNVHFKTGEVCLDILKNAWSPAWTLQLVCRAIIALMAHPEPDSPLNCDSGNLLRSGDLR
GFQSMAKMYTRLAAMPKKG
>Sgl45527 E3_adaptor/Cullin_RING/DCX/DWD 60.6 7.3
MEASGVPRRLKGHTATATSCIASRQRPRVIFTAAEDGCMCLFDLRCKEVQQIMKLGNDAI
SSLCFKEGNENMIYLSSGTEVRCFDVQMATFEKPMESYKYNKEEINQISCNSKSSFLAAA
DDSGDVKIIDIQRRCPFKTLRSGHASICSSVQFVPWKPWEVITGGLDSKMIMWDFSKGRP
FLVVDFGNVEETSKNSGQFCNPAFIHAIAVPDMDILINIEAELAADKSKGAAKPRKNSQG
GSSSATGGPDADTENQNKAKRLHLDHTLEGHTAAASCVTYSSFGERGKFIISGGNDKTVK
VWDWSRHLDETQPKADTAAVSSINLPKKVNWLCTTPTDSENLVVCDTSKVVKGV
>Sgl45547 E3_adaptor/Cullin_RING/SCF/F-box 15.5 0.0
MAALPTEIIAEILCRLPVKSLFRFLCVSKSWFSLIKNPKFIKQHLNQTLNSNSHRHLLLT
YSSLSSSPINRQFKFSKLPHPLKLKSPEKKPKILFWGSCNGVICISDADRNDIVLFNPTT
KTYRKLPKTKYPYPNEFAVFGLGYDAESGDYKVLRLMQCVGPDDGVLNDARVYSFKRNSW
KRVKDIPYNLIFDRNHGVFVNGGLHYVVSKVPFQSEYKSIARFDVRTEQYSLLECPDYDH
SLRCWTMYLGDLGGRLSCSVNFDLNGCGEVWMMDDYGKKESWIRLLGINKKEACLIDIKA
ITWCNDGNMILVMVDGELRWYDMRRGRAMRAGVLEGLPGEGFETGVFVESLVMLNEDKVD
FGAGIKTRKDEVKTGAKTVAQRDEVKTGEGTTAKKDKKKSVDDFLSKGFKLRL
>Sgl45575 E3_activity/RING/U-box 114.3 0.0
MATSAAFSSLRRRRSPPLEAFLAPVDLTDRGIIKTLLSVANELVELHSGKKLPFQKKNFL
SLVRKIEVFVVLLDYLKEYRPISRFSYTEIMCFKELYLLFYRCKILLDYCAQSSKLWMLL
QNQSISGHFHDLNQEISTLLDVLPIRDFGLSEDVREQIEMLKRQLSRAKGYVDKKDEMLR
NRLYSFLNEFEDGKVPHLTELSNFFIDQLRIFDAKSCRAEIEFLEEQIVNHEGDVEPTAS
VLNGFVALTRYCRFLLFRFEEEEMEVVVESIKKMRKAMISQEIADTFLTIPKDFSCPISL
ELMRDPVIVSTGQTYDRSSISRWLDEGHYTCPKTGQMLAHTRLIPNRALRNLIAQWSAAH
GVPFEPLEGAESSSELAAAASSKAAVAANQATAYLLIQKLASGSGDAQAIAAREIRLLAK
TGKENRAFIAEAGAVPHLKRLLSSANAVAQENSVTAMLNLSIYDKNKAKIMDEVGCLKSI
VDVLRFGHTTEARENAAATLFSLSAVHDYKKRIADENGAVEALADLLRYGTPRGKKGAIT
ALFNLSTHTENCVRMVESGAVTAVVEALGVDGVSEEAAGALALIVRQSAGAAAVGREETA
VAGLIGMMRGGTPRGKENAVAALLELCRCGGAAATERVLKAPALASLLQTLLFTGTKRAR
RKAASLARVFQRRENAAMRYGGLGVGHQLAGNSVPNRDPSFVGDVSVPMSISVPVVQG
>Sgl45587 UBD/UBC-like/UBD_UBC 135.6 0.0
MNEEEQEYQISRETFLAYFVFLKFVEDCSLITSQFLGIMQASRARLFKEYKEVQREKTAD
PDIQLACDDSNIFKWTALIKGPSETPYEGGVFQLAFAVPEQYPLQPPQVRFLTKIFHPNV
HFKTGEICLDILKNAWSPAWTLQSVCRAIIALMAHPEPDSPLNCDSGNLLRSGDLRGFQS
MAKMYTRLAAMPKKG
>Sgl45664 E3_activity/RING/U-box 114.2 0.7
MIASWRRKRAGRGADGGSKRKLSELIVPSHFRCPISLELMKDPVTLSTGITYDRDNIEKW
IEAGNVTCPVTNQVLKTLEPIPNHTIRRMIQDWCVDNRSHGVERIPTPRIPISSDEVGTI
LEKIETARAPNECQELVGKMSKAMKESERNKRCILENGASKSLSLAFQTFSETEGETVIS
LLEEIMSVITSMTPLEAQAQGSLRTPKSLGRLVWFLRRGGLSGRRSAVLILKELVLTPKD
QGKLVESLVAMEGTIEGLVKLVKEPICPSSTKASLVVIYNIITSSSSHVHASSSNKNIVI
GKFIEMGLMTLVLDILVDAEKSISEKALGVLEGLCRSREGLEAAYDQALMVPVVVKKILR
VSDLATEFSVSILCRLCENEGREDGGVIVEALQVGAFQKLLLILQVGWNINERIKEKVTK
LLKLLNLYRSKIECIESTDFKDLKRPF
>Sgl45665 E3_adaptor/Cullin_RING/SCF/F-box 12.4 0.0
MMMDLPTPLIMDILSRLPCKTLLRSRCVSKSWKYLIDDTHFISLQLKRSLENTTNHTLLL
RDCYIYSVDFPKLDEAVAIDHPLKSYSIGTDLVGSCNGLLCLSNGEGKQMNGTIIYNPTT
RKRWELPVSRFKFPENAFCVERTVYGFGYALGSDDYRVVRIIQFYNSYPDFYESEVKVFS
LKTLSWRRVQDFPHECYLTFKRQRGMYVNGYLHWIVTFKPESDGSKQILAFDMDSEDYKA
VPLPKYSPGEVHLNVEVFQQLLCLLVNYPTIRSEVWVMKVYGIEESWTKLFAIAQDDVIG
PFGYVRPLAYSKDGSKVLIEPDLGKLIWFDVERQKVETVKIRNMPTNPEITVFVESLVFG
SRKTHQRNKRSNERKRLENANITAMPNSSAVISGGPLDDVHNDTRNSDKDQQTLNGNHNP
RKKGQRDNMGGFLSKGFKLKL
>Sgl45666 E3_adaptor/Cullin_RING/SCF/F-box 49.5 0.2
MADYLPAPLVTEILSRLPAKSLLRFRCVSKTWKSLIDGPNLIKLHLKNSLQNTTNHTIIL
RHFSLFYLGFPTLNQVKEINHPLKSDCYGTEVVGSCNGLLCLSNGEEQGIEGTIIYNPVT
KKSRELPVSPIEFPKDDIFPFCERLVYGLGYDKGCDDYKLVRICQFYCGNPDFYDSEVKV
YSLKMNSWRRVMDFPKEYFLSYKRVSGVFVNGCLHWVVSKNPESDGAKSIIAFDLGSGRC
RIVSKPRALCGTCHINVDVLCGSLSVLVSHPEIRSEVWIMERYGVEGSWTKLFSIAYGSV
LGNFEYVRALVCSSDGSRVLLQKDMKSLFWYDLRTQRAKRVNVHGLPDWFEAQMLVESLV
PLDGYKKSKKKKPKRKRTELSEQADSLFTMLPEPLLLNIFSRLPADTLLQLTYVCKAWNN
VINDPEFAKMHLEVSAKCNENLNFVLGHEKLHLIDFNKLNAAVQINHPLVYPKGWTCVLG
ACNGLLCLYNREKDLAIWNPLTGRCHKIPIKETKSPNSYDMHFYMYGFGFDSSSDDYKVV
QIFQMHSFKGPSHDYFGSDSSDSESDICYGSEVQVYSLKDKCWRKIKCFPFTLSYVCPGV
FVNGALYWVADAKRGMDSISNVILSFDLGSEECRVVPQPDYGNLNFHLSLWLFGGSLCIL
CHYPRHGVDIWVMEDYEMQTWCKLISITQPKPIKYFEYIKPLTYSKNGSEVLLELDYKKL
IWYNLNKKTVRHVNISGLPESFDTEVFYKSLVDPGNLIPRQKKQSVQSCNFLAVFPEKLL
SHVLSYLPIKTLLRFQCVCKKWYNLINDSEFIKMQLEVSSNCNSSSLLILGGEKLFSLDF
QLLDDAMKVIHSRVCPDGLTNIVGSSNGLVCLHKDSDIALWNPWTGKYERLPPANFQFHV
SSGMYYCFIHGFGYNPTSNDYKVICILQLHNNLKGGSVHSEIHVYSLRSKSWGTTRKFPY
IICYPCSGVLASGALHWVARQNPELYSSSNLLIAFDLGSEKCRVVTQPNYIDTDFHMSLG
LLRNSLCLLCHYPKQSVDFWVMTEYGTESWTKLFSISQPKLIKQFEYLKPLGYSNDEAEV
LLEQDNEKLLCYNLVKNTIRYVKVRGLPTSFEAVMTCGSLVQIGTPPKNFHEKAPNKSQS
VKAKVRDGSDTFLAKGFKLKL
>Sgl45667 E3_adaptor/Cullin_RING/SCF/F-box 13.1 0.0
MAENNCDRFSNLPEELIHHIFSKFSYNEMNSMMNVSKKLQNLCFSSSTMAFGAYLHHPSS
TALDFRDFVDEFLAKASFRLTNSTTPLLRSLCLTWRRGKDGRKLHCSQALPQSSLASCVE
TLVVNYYKIELLEASNFGEWISSSFPCVKKLVVRFEDCSFGTNQTLSIDHCPTLEEIEVS
GPENSTYDHNLRLKIISCPSLEHLTIKNLRFEEATCEITIMGEQLRTLSIDGAMLLNCSS
LAHVFKIHAPNLRVFHWRGSAIKYFVDSTNSFQHLEKAVLDVKGKHKLLYYKFVNKLLSS
LQHAIHLEWRSTSKDYVFRELHFKVRRNHMVKIM
>Sgl45677 E3_activity/RING/U-box 103.6 0.2
MGNELPEYFKCPISLEIMVDPVILSSGHTFDRTSIQRWLDSGHRTCPITKLPLPNHPPLL
IPNHALRSLISNYAPPHHRLSTIGSEANSISQLAPLIEALVSKSSTEVEKVESITRLLAV
SKAHPGEFRARATDSGGLSAVLRCIGPECGPDLQEKSLSLLLNLSLDSDDNKVGLMAEGV
MEKLTAALVGPNAATAATLITSLATLEVNKAAIGAHPGAIRGLVTLMGGGRREKKEAATA
VFALCSFPENRRRAVDCGAVRVSLSMAKSGAERAVEVMGMLAKCTRGREELVRCCEEVVG
VLVWFVKNGSSRGVQYGLMTLNLISCCSERVKVEVRRFGVLEMCFGFMEEHYGNEKIIKV
ASNLAKVLQEN
>Sgl45685 E3_adaptor/Cullin_RING/SCF/F-box 18.1 0.0
MESQRLHEDVLMEILVRLPVKSLVRFTCVCKYWLSIIKSPDFATKHYAARLDRLRYLSHN
YDCFLTIRSRACSIFICNTVNMALETAFKFRPAVTYEPPRFEIGHYKVIKDYLIYGPCNG
LFVINLFIHKREQPVLLLWNPATRKVFKLPENKYNYHGNDCVALGFDHVTNDYKVISFLS
PSCTEDPMSLNSKGNSRLIPWYSLATNSWRQVDGGFDFNHLKKSVYCKPSNTSSSLNGRK
NHFLLGDSYPFPNGINPTFSLLTFDMVDEVFVETAMPDEITTNDLSFDGFLHQGSSHDTR
YPTIYSFGFNKAGQSDYDPIEVHIWVLEGYGRTGFWKKQQSIILSEYSWGNAKVAFWKIT
SYHFTTEYLTSVRKILGDGGTIIGYNESLVSIASKLPSPANHLSVETNDDTSCPQSVDTG
PPELMQDDDHDPSLSAQILENREEEEEEDDDKSSTDSAFLIPPRRDPSRMFDIEYDIQRR
TEQERLCQLPYCLREVKQPMKNNPYTF
>Sgl45688 E3_adaptor/Cullin_RING/SCF/F-box 12.3 0.0
MLDQVKRSEMGDCISELPDDVLCYILSFLTVRDAVRARSLSRRWRYLPYHCPTVLRFDAL
NVLGNERYSCVSHQSKFVRLVDHLMDTFTLRPSVLKLQFHLDKLYSSNIDTWIVRFVTMG
IKELDLFIPNYVFSCYLLCPWMEASSLTCLRLSFCALNLSSCCTSWISQLTTLQMSAVSM
DCNDMEFILSSALNVTSLSLAYCCNPTIQCLKVELLGLKKLFIEELLMDLKLNCPNLEVF
EFTGRLSNITLAHLPFLRQAKVFPNLHRDGGSLIFAELIRFAPHLKALSFSVMTVVQVQP
LPFEARTINSSLKQLDLLMFVPYCFDLFSITCFINACPSLEILRLKLKPGSDPRQSPEKE
YPDCQHNKLKEVEIDGHSERFNSLELALYLLRNAVALEKMVIVCPDRINNNKARLTTLLQ
NANSSVELIIQCFS
>Sgl45708 E3_activity/RING/RING 15.9 8.3
MKKLAAHSVQKKQEKDEQEDKLMLQKARELEAFDQQNHGAVPHQSDKSYYHNKNGFQGAN
SVKATSFEEEALRTMKAFWLPSATPEAPAKVEAPSTSTTCPEGSEKLKLKSLFPVYFTEE
NDDDNKSKVFDKKHICPSCKVTLTNAMSLVALSSCGHVFCKKCADKFVVVDKVCLVCDKP
CKEKSLVSLKKGGTGFAGHDENLEAKDFKHLGSGSGLGLVRPAQKV
>Sgl45737 E3_adaptor/Cullin_RING/SCF/F-box 14 0.0
MCSKKFKDSSKSETLHNISSFPDEVLEKVLGLLESHKDRSSVSLVCKDWYNAERWSRTHV
FIGNCYSVTPEIVARRFPKIRSVILKGKPRFSDFNLVPENWGADIHPWLLCFAKAYPFLE
ELRLKRMSVSDESLEFLALNFPNFKRISLLSCDGFSTDGLAAIATHCKNLVELDIQENGI
DDRSGSWLSCFPENFISLEILNFSNLNSEVSFSSLLRLVGRCKSMRVLKVNKYVNLEQLQ
RLLIQAPRLTQLGTGAFSQELQPSQYASLENIFNNYRSLQTICGLWETNSLYLSVLYPAC
SGLTFLNLSEAALQCDELAQLLNHCPNLRRLWVMDTVGDKGLEAVGSSCPLLEELRVFPA
SPFEADIGQGVTETGFVAVSYGCPKLHYVLYFCREMTNAAVATIVQNCPDFTHFRLCIMN
PGEPDHLTNEPMDEAFGSVVKSCKKLKRLALSGLLTDLTFEYIGKYAKNLETLSVAFAGS
SDLGMQCVLAGCPKLRRLEIRDCPFGNSALLSGLERYESMRSLWMSACNVTMSACRRLAT
EMPRLNVEVIKDEDTDECNANKVYVYRSVAGPRKDAPPFVLTL
>Sgl45744 E3_adaptor/Cullin_RING/SCF/F-box 14.4 0.0
MCSKKFKDSSKSETLHNISSFPDEVLEKVLGLLESHKDRSSVSLVCKDWYNAERWSRTHV
FIGNCYSVTPEIVARRFPKIRSVILKGKPRFSDFNLVPENWGADIHPWLLCFAKAYPFLE
ELRLKRMSVSDESLEFLALNFPNFKRISLLSCDGFSTDGLAAIATHCKNLVELDIQENGI
DDRSGSWLSCFPENFISLEILNFSNLNSEVSFSSLLRLVGRCKSMRVLKVNKYVNLEQLQ
RLLIQAPRLTQLGTGAFSQELQPSQYASLENIFNNYRSLQTICGLWETNSLYLSVLYPAC
SGLTFLNLSEAALQCDELAQLLNHCPNLRRLWVMDTVGDKGLEAVGSSCPLLEELRVFPA
SPFEADIGQGVTETGFVAVSYGCPKLHYVLYFCREMTNAAVATIVQNCPDFTHFRLCIMN
PGEPDHLTNEPMDEAFGSVVKSCKKLKRLALSGLLTDLTFEYIGKYAKNLETLSVAFAGS
SDLGMQCVLAGCPKLRRLEIRDCPFGNSALLSGLERYESMRSLWMSACNVTMSACRRLAT
EMPRLNVEKRRPSLCSHTLRLKHLISWFNLHMIDRIMFCEDEKYMVLSPLGSPFHQLLSI
QHDTYI
>Sgl45752 E3_adaptor/Cullin_RING/DCX/DWD 51.5 1.2
MASTSRKRENSTTDEEQQQKHHSKRQNLSSLKTDSLHRVKLNPADCDLAFHIEGDGLIGY
GLRDLGFAYWWSGARGDIGITTGKYCFGCKIIFNWPVSMHETHPDLRHISCIGISRGDDL
IGKLGETKHSFGYDGTGKFSNAGESDEDGERFGIGDTIVCLVDLESKPFSSLGYTKNGEQ
LGVFYFEAGTNGLEVIDSPTTELPWKSAFFPHILLKNTAVKMQFSIEDGLVPKEGYKPWD
LAIKDGNAIMGPGFSDPNDREVIMMVGLPASGKTTWAENWIREHPEKRYILLGSNMAFDH
MKIPGLKRKRRYNEILDRVMDLAAGIFNTLFIRASQLSRNYIIDQTNVSKVYRTLVFSYF
SYPCRIFAGYNKTMRVFDVHRPGRDFAQHSTLQRSKEGQSGIISAIAFSSAHSGMLATGS
YDQTTAIYREDNMELLYVLHGQEGGVTHVQFSKDGNYLYTGARKDPYIMCWDVRNTVEVV
YKLYRSTEQTNQRISFDIEPIGRHLATGGQDGLVHIYDLQTGQWTSSFAAASDTVNGFSF
HPFLPMAVSSSGHRRFGLPDDADDTVVPLSSDENCASVWSFSYTSATENPMSINGEDSLG
MLEDEKP
>Sgl45759 E3_adaptor/Cullin_RING/DCX/DWD 81.3 9.4
MAENHSQLQHNENQEDEQHQFVETNALQIENDETFEVDDTNSNDHQGQVYSWPQIQFDVQ
PYKSCHFYRQFRSSSNPNNFLKSVKWSPDGSCFLTSSEDSTLRIFSLPDNDYLAGSIASG
PDEDSYAAKLVINEGESVYDYCWYPYMSASDTTSCVFATTTRDHPVHLWDSTTGELRCTY
RAYDAMDEITAAFSIAFNPTGTKIFAGYNKTMRVFDVHRPGRDFAQHSTLQRSKEGQSGI
ISAIAFSSAHSGMLATGSYDQTTAIYREDNMELLYVLHGQEGGVTHVQFSKDGNYLYTGA
RKDPYIMCWDVRNTVEVVYKLYRSTEQTNQRISFDIEPIGRHLATGGQDGLVHIYDLQTG
QWTSSFAAASDTVNGFSFHPFLPMAVSSSGHRRFGLPDDADDTVVPLSSDENCASVWSFS
YTSATENPMSINGEDSLGMLEDEKP
>Sgl45761 E3_adaptor/Cullin_RING/DCX/DWD 30.9 3.4
MAENHSQLQHNENQEDEQHQFVETNALQIENDETFEVDDTNSNDHQGQVYSWPQIQFDVQ
PYKSCHFYRQFRSSSNPNNFLKSVKWSPDGSCFLTSSEDSTLRIFSLPDNDYLAGSIASG
PDEDSYAAKLVINEGESVYDYCWYPYMSASDTTSCVFATTTRDHPVHLWDSTTGELRCTY
RAYDAMDEITAAFSIAFNPTGTKYAPFLEIEK
>Sgl45766 E3_adaptor/Cullin_RING/DCX/DWD 16.5 6.1
MEADDSERVLPFQLQFDKPAPSQIKMAEWNPEKDLLALVTDDSKIILHRFNWQRLWTISP
GKCITSLCWRPDGKAVAVGLEDGTISLHDVENGKLLRSVKSHNVAVVCLNWVEDDGHGQD
NRENTMPFEDRSLRFFPPAPRVPRIPGVVSGDSTLMDSTEDSFQDLLNTSHQRFNILCSA
DKDGGICFSIFGIFPIGKINIQSLSLPLISNQVAYQIIHASINKVALSKDFCRLIVICSG
ELVSSSSEVNHEPLSRPETEGMHCLVLDTSVFQKRKQELHQVAQQVSSIEDLTEVIRASL
SIMYKQWSDAMQMFHDKFNSLSTLIVSNGLDSSPQDEFLSLLGGARTSPPIHQFLVNSLG
ESGLKRVTKAVSNAGKELQLILLDHIQPAAEIIGYRMGELRGLSRWRARYGGIGLDEKLI
DNGTEKVGMLLVQVVRFVQILSSVTQQFSNFFSWLLRCIKILMSEPSDQLPSYNSELVII
FLKFLYDRDPVKLLLDQSVDQSVQLNLYTKQRVEELVKLGGFADTECLHRTLAKEFQYME
SSFKEAFNMPYTTISKKIVCEQMLPLYPFRSSPPSTPISFPTSISFYWDAAPDVSTCETS
QENLVDYIAFQIPECSSSDASNCILILRGIINEADNVKSSYTTVDALLLSVSREFSCIDL
SLYKERQLILLLNETTAASDSSGNALLMMIQTSDLPFVSISTSTSLKFWNSDQLQDCILP
VQTESAKVRSIPHNVVSPLAVSSSRGVGCVFAARKRALVYILDEDEEEEEEETSDMD
>Sgl45777 E3_adaptor/Cullin_RING/SCF/F-box 15.1 0.0
MEGENDYISDLPDTILHQILSLIPTKLVVSSSCVSKRWGEISAGFFRYAHTFQFDEEFAK
QQTPDQLTENINRILSLNKSEKIRKFKLVFSPTIENMFDVTNWILFATGKDVEELDLDFL
FPTHFLSPVDAVDLEDVFVLPNFMFDCKTLETVKLSRCILGLPEQYTGFRGIQTLCLSQV
HVTDSMLGSLLSNCTLLEVLVLKECGALTSIRIRSHSHTRLQRLTVYECNNASFIEISGP
KIRSLLISASILKDCTLEDMFVLEEVLIGTRGYEHFDAYDDLKYLKLFGQLKHVRTMYIN
LSHSVPRWVKMYMVPFKNLRELHLVNSPLFGLFKSGVCSLLWCPSLQKLTIELPTVSEEE
NFSWVCTDPDSPRKEREFNSLRTVTFRNFRGTDADFELATHVLERAPSLESILLIAPQNL
NAQKVTAKDEVSSFWTLKIKETELWLWQKGIFEKFRYFPKVSEIADIQASEGDEHDISLL
SFFDLHYVSDVYNN
>Sgl45778 E3_adaptor/Cullin_RING/SCF/F-box 20.1 0.0
MEEGEKDYISDLPDAILHQILSLIPTKFVVSSSSVSKRWREISADHLLFASALEFGEEFA
KQQTPDQLTETLTRILSLNKSEKILKLKLVFSPRNEEHMVNATNWILFATCKGVRELDLD
FCRHIYIHFLSPAHVVGKKDVFALPNFLFNCKTLETVRLSRCILDLPEEYTGFRGIQTLC
LKEVHVTDSMLESLLSNCTLLEVLVLKECGALTSIRIRSHTRLQRLTVYECYNAMIIEIS
GPKIRSLLISAGHLDACKLEDMFMLEEVFVGTRGDEFGGVFSIFIKVFSQLAHVRTLSLY
LGHLVPNLIKDFKVKFGNLRELHLVNSPLFGMFNSDVYCFFRHCSCPVLQKITIELSTVS
EEENFIWEFRKPNIKPKERVFKSLRTITFRNFRGTNADIELATHFLERAPSLESMLLIAP
QNLNSQKVAAKDEVSFSALKEKETKVWQKAVCEKLRYLPKASEIADIRVCEGDEYDDGLL
SFFNWHHVSDVYYK
>Sgl45799 E3_adaptor/Cullin_RING/DCX/DWD 29 0.4
MTLSLLEMNSHDFIPNSCKIVDHEYLCFDQPAAEIIGYRMGELRGLSRWRARYGGIGLDE
KLIDNGTEKVGMLLVQVVRFVQILSSVTQQFLYDRDPVKLLLDQSVDQSVQLNLDTKQRV
EELVKLGGFADTECLHRTLAKEFQYMESSFKEAFNMPYTTISKKIVCEQMLPLYPFRSSP
PSTPISFPTSISFYWVCSLLHNSISFFKWDIIYNVESPLSAPDVIFGEEDDKFVSFILST
DPNNSPMHNLTDWNCKDPSRLLSFLLQLRWCCGLRSTGCSSAKPLSRDCAGAWCCAAAVV
NVLDVLVWDLTAGKLLHDFKFHDGHIRSLDFHPLEFLLATGSADRTVQFWDLETFEMIGS
ARAEATGVRAMTFHPDGRTLFCGYENNFKVYSWEPVICHDAIDMGWSTLGDLCINEGKLI
GCSYYRNSVGAWVADLSRVKPYGTGDSGESQERSPVGKVGKRETPTAEGVEPVVRSSLSS
RSTSPDADAKEIKNIYVDYEKPVSFRKARSLNASKTELRSDSKQSSKLSSRKQNTPNTAS
GRSNGQVGGRSFTAPSFVPRESSSGKAYSSSRRESITPMKHGGGGAIKAAHSRKYSHSKF
DIDDADPNFLDRLVQEVGAMELDEDKNPTPESAEEKFEEKTSLPSASNPRSEGGNPVDGK
EVPNTKVVNRVALGRTRSLVEKFERRGKFDGDEDQTVSASPDIIADRINSSTMLKEEPQV
SGRDSASASDSYIIEDLMENHDVILSGLRSRLTKLQMVRHLWERNDIKGAITSLKKLPDH
SVQADVISILMEKMEIVTMDLFSCLLPILVGLLDSKIERHAKMTLEMLLKLIAQFGPTIR
STISAPPSVGVDLHQEERIACCKQSFVQLQQIQGLLPALARRGGSLAKSALELNLVLQDH
SI
>Sgl45800 E3_adaptor/Cullin_RING/DCX/DWD 83 4.1
MAKRSYKLQEFVAHSGNVNCLRIGKKACRLLLTGGDDNKVNLWAIGKPTSLMSLCGHTTP
VESLAFDSAEVLVLGGASSGTVKLWDLEEAKMVRTLTGHRSNCTSVEFHPFGEFFASGSA
DTDLKIWDIRKKGCIHTYKGHTGGINTIKFTPDGRWVVSGGFDNVXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXCRGFSSPLRI
>Sgl45806 E3_adaptor/Cullin_RING/DCX/DWD 16.5 6.1
MEADDSERVLPFQLQFDKPAPSQIKMAEWNPEKDLLALVTDDSKIILHRFNWQRLWTISP
GKCITSLCWRPDGKAVAVGLEDGTISLHDVENGKLLRSVKSHNVAVVCLNWVEDDGHGQD
NRENTMPFEDRSLRFFPPAPRVPRIPGVVSGDSTLMDSTEDSFQDLLNTSHQRFNILCSA
DKDGGICFSIFGIFPIGKINIQSLSLPLISNQVAYQIIHASINKVALSKDFCRLIVICSG
ELVSSSSEVNHEPLSRPETEGMHCLVLDTSVFQKRKQELHQVAQQVSSIEDLTEVIRASL
SIMYKQWSDAMQMFHDKFNSLSTLIVSNGLDSSPQDEFLSLLGGARTSPPIHQFLVNSLG
ESGLKRVTKAVSNAGKELQLILLDHIQPAAEIIGYRMGELRGLSRWRARYGGIGLDEKLI
DNGTEKVGMLLVQVVRFVQILSSVTQQFSNFFSWLLRCIKILMSEPSDQLPSYNSELVII
FLKFLYDRDPVKLLLDQSVDQSVQLNLYTKQRVEELVKLGGFADTECLHRTLAKEFQYME
SSFKEAFNMPYTTISKKIVCEQMLPLYPFRSSPPCTPISFPTSISFYWDAAPDVSTCETS
QENLVDYIAFQIPECSSSDASNCILILRGIINEEDNVRSSYTTVDALLLSVSREFSCIDL
SLYKERQLILLLNETTAASDSSGNALLMMIQTSDLPFVSISTSTSLKFWNSDQLQDCILP
VQTESAKVRSIPHNVVSPLAVSSSRGVGCVFAARKRALVYILDEDEEEEEEETSDMD
>Sgl45816 E3_adaptor/Cullin_RING/SCF/F-box 14.8 0.0
MEGENDYISDLPDTILHQILSLIPTKLVVSSSCVSKRWGEISAGFFRYAHTFQFDEEFAK
QQTPDQLTENINRILSLNKSEKIRKFKLVFSPTIENMFDVTNWILFATGKDVEELDLDFL
FPTHFLSPVDAVDLEDVFVLPNFMFDCKTLETVKLSRCILGLPEQYTGFRGIQTLCLSQV
HVTDSMLGSLLSNCTLLEVLVLKECGALTSIRIRSHSHTRLQRLTVYECNNASFIEISGP
KIRSLLISASILKDCTLEDMFVLEEVLIGTRGYEHFDAYDDLKYLKLFGQLKHVRTMYIN
LSHSVPRWVKMYMVPFKNLRELHLVNSPLFGLFKSGVCSLLWCPSLQKLTIELPTVSEEE
NFSWVCTDPDSTRKEREFNSLRTVTFRNFRGTNADFELATHVLERAPSLESILLIAPQNL
NAQKLTAKDEVSLWTLKIQETELWLWQKGIFEKFRYFPKVSEIADIQASEGDEHDTSLLS
FFDLHYVSDVYNN
>Sgl45818 E3_adaptor/Cullin_RING/SCF/F-box 18.7 0.0
MEGEKDYISDLPDAILHQILSLIPTKFVVSSSSVSKRWREISADHLLFASTLEFGEEFAK
QQTPDQLTETLNRILSLNKSEKILKLKLVFSPRNEEHMVNATNWILFATCKGVQELELDF
CRHIYIHFLSPAHVVGKKDVFALPNFLFNCKTLETVRLSRCILDLPEEYTGFRGIQTLCL
KEVHVTDSMLESLLSNCTLLEVLALKECGALTSIRIHSYTRLQRLTVYECYNAMIIEISG
PKIRSLLISAGHLDACKLEDMFTLEEVFVGTRGDEFGGVFSIFIKVFSQLAHVRTLSLYL
GHLVPNLIKDFKVKFGNLRELHLVNSPLFGMFNSDVYCFFRHCSCPVLQKITIELSTVSE
EENFIWEFRKPNIKPKERVFKSLRTITLRNFRGTNADIELATHFLERAPSLESMLLIAPQ
NLNSQKVTAKDEVSFSALKEKETKVWQKAVCEKLRYLPKASENADIRVCEGDEYDDVLLS
FFNWHHVSDVYYK
>Sgl45839 E3_adaptor/Cullin_RING/DCX/DWD 119.7 6.9
MAKRSYKLQEFVAHSGNVNCLRIGKKACRLLLTGGDDNKVNLWAIGKPTSLMSLCGHTTP
VESLAFDSAEVLVLGGASSGTVKLWDLEEAKMVRTLTGHRSNCTSVEFHPFGEFFASGSA
DTDLKIWDIRKKGCIHTYKGHTGGINTIKFTPDGRWVVSGGFDNVVKVWDLTAGKLLHDF
KFHDGHIRSLDFHPLEFLLATGSADRTVQFWDLETFEMIGSARAEATGVHAMTFHPDGRT
LFCGYENNFKVYSWEPVLCHDAIDMGWSTLGDLCINEGKLIGCSYYRNSVGAWVADLSRV
KPYGTGDSGEPQERSPVGKVGKRETPTAEGVEPVVRSSLSSRSTSPDADAKEIKNIYVDY
EKPVSFRKTRSRNASKTELRSDSKQSSKLSSRKQNTPNNASGRSNGQAGGRSFTAPSFVP
RESSSGKAYSSSRRESITPMKHGGGGSIKAAHSRKYSHSKFDIDDADPNFLDRLVQEVGA
MELDEDKNPTPESAEEKFEEKTSLPSASNPRSEGGNPVDGKEVPNTKVVNRVALGRTRSL
VEKFERRGKFDGDEDQTVSASPDIIADRINSSTMLKEEPQVSGRDSASASDSYIIEDLME
NHDVILSGLRSRLTKLQMVRHLWERNDIKGAITSLKKLPDHSVQADVISILMEKMEIVTM
DLFSCLLPILVGLLDSKIERHAKMTLEMLLKLIAQFGPTIRSTISAPPSVGVDLHQEERI
ACCKQSFVQLQQIQGLLPALARRGGSLAKSALELNLVLQDHSI
>Sgl45842 E3_adaptor/Cullin_RING/SCF/F-box 34.4 0.1
MEFLPTQLLTEILSRLPVKSLLRCRSVAKSWQSLIDDKYFINLHLKRSSQNPNHHTLMIK
DCFLQDNYTPTNDPYLYSVDYPTLDHSKSINLQFQCNPLETEIVGQCNGLLCFADGSTLS
TLLYNPSTREKWVIPDSPVDIPGYVVLCDRIVYGFGFDHVNDDYKLLRIIQSREKTVDFH
VTEVKVFSLKSNCWKRVKDFPKEYYISYGMCWGIHVCGCLHWLAIRKPDREKVIVAFDLG
TEEYKVVPQPKYFGGGKDCFVVEGVLDGCLMMQALYPKNRTDVWVMKEYGVKKSWTKLFT
IPQWGCIGFYEALKPIVYVKENGSVKVLVEKNFKELIWIDLRKQKAESVKTLGIPWSFDA
VLLVESLVPLNNHRKKPVKKKKKKQRNNSVPSQNVQPVVAFPEKVLCHIFSWLPVNTLLQ
AQCVCKTWYNLINGTEFNTMYLENQSKCSSSLSLILKGDVFFSVNVQLLDKVSKVNHPLL
CNEEYTDIVGCCNGLVCVCADLNLALWNPWTGKHEKVCCPDFQLVHSSNVFRCLIHGFGY
DPTTNDYKILSILQQYSQLKGGTVDTEVQVYSLKTKSWKRIQHFPYFVSYPSSGVFTNGA
LHWVARPIPDLYSSSNLLLAFDLGVEKFRVVTQPNYVDTDFQMSLGLLGNRLCFLCHYPK
ESVDVWIMTDYYNESWTKLICISQPSVIRRFQFMKPLAYSQDGSEVLFEQDNEKLLWYNL
KKKTVKYINMPDLPKVFYSVICSGSFVPIGNATRNYQVVDEKPSKEFQKSRNTKERHNLD
GFLTKGFKLKL
>Sgl45843 E3_adaptor/Cullin_RING/SCF/F-box 13.2 0.0
MDQISFISPLIMADHLSELLVSEILSHLPVKSLLRFRCVSKPWKSLIDSKYFINLHLKNS
SKNPNKLVTQYGIVKINKKIGRDPFIYVVDFPTLDNPIVINKYDCPFYCSCRTKFYGSCN
GLIHLVNTVGYKRQISYICNPFRSTRKFRVIPESETDLQCSRVFYGFGYDSINDDYKIVQ
IVTLLSWTAPRTDTDTDTFCCNSKVNVFSFKDNCWKDVGYLPKYYIDYKVEAAIYFNGCL
HWIASDVPYLGTSRLMLVFDLGTEKFSVMPLPELAESSRGMSKSCYINVGVLKGCICIWE
CCDVSPPSLLKIDVWIMKEYGVNESWINLFSIDLNKFSSRLKNHCDYNCWRYIGYRKMNG
FEQVLINYQHSFAWYDVQQETVTFVRTEGFFHGLIAMLLVESLVPLESHT
>Sgl45851 E3_activity/RING/RING 17.1 9.5
MMMAEETLNLGLMNDFDFSDDDDDGFGIDADAFFNILNEDNPDQSPFPIDPFYPSTDNTQ
ESGSAIHVNDHLNIPSQTDYGAASENSAETVEVMDQLPHSSSPEMVLSEVNDTSFSKEST
EVNAFQLSNYANTEFLPFGQDWQSMLQMSSANHPNSLAGLSHDVMSTNEAMRGNMTSDLD
DSRSSHPWSDTKISIGAQAGAADVTASQVHMYDFFDGAGTESFFGGDYPVQHVDTMNTYD
NSSGSTTTEETSVEPYHWRLVGKSFMKQSVEAKDEKDYTLPLHNGSEWKSSEANTDGLLG
GFSFGSDAQQFLSYAETQYSGSVAGGPANYFPNASSSDNKISNVQLLEHPFSSADLFSEL
SSSYYNIEREDARNQHSIVKPNPWEGPLRASQRCLSEGQSDVDDNNDLCILENMSEPARL
QTFSAHKKPVTLMPAAFTPQCSKTMTPFHQMGPSGTKSKASDERLIFQSLVQDLSQPKSE
ASPPDGVLAVPLLRHQRIALSWMVQKETSSLHCSGGILADDQGLGKTVSTIALILTEKST
SAKTSKGKDSAELETLDLDEEDDKQMVNKIQSVKGRPSGGTLIVCPTSVIRQWDAELRSK
VSSDVGLSVYVYHGNNRTKDPYELAKHDVVLTTYSIVSMEVPKQPVVLKIGSDGRQIEVE
DSSVKSNKKRKHSSTSDNRPSKKGMDSQSIKPVALPLARVGWFRVVLDEAQSIKNFRTRV
AQACWGLRAKRRWCLSGTPIQNAVDDLYSYFRFLKYDPYSVYNSFCSMVKIPISKTPSKG
YPKLQAVLKNIMLRRTKGTLLDGKPIINLPPKTVTLKKVEFSEEERDFYSRLEADSRAQF
QAYADSGTVKQNYVNILLMLLRLRQACDHPFLVEGGSSSIVKSSIRTAKSLPREKQIFLL
SCLEGSLAICGVCRDPPEDAVVCICGHVFCNQCISLRLNGDENQCPSTNCKSELKSSHVF
SKGTLNSCLSDLVNQDSSHVAFAAGSSDQSEFIDSQPPVRFESSKIKAALEVLRALSKPH
VSVPDDVTVLPVASDINLLDKSDAAPCATDNEHSNVSDGLSRGNVVVKEKAIVFSQWTRM
LDLLEDCLKESSIQYRRLDGTMSVSARDKAVQDFNTLPEISVMIMSLKAASLGLNMVAAC
HVVLLDLWWNPTTEDQAIDRAHRIGQTRPVTVVRLTVKDTVEDRILALQQKKRELVASAF
GEDEKDSRQSRLTVEDLTYLFMA
>Sgl45880 E3_adaptor/Cullin_RING/SCF/F-box 17.2 0.0
MNNPPLPQRRIPPTTISDIDDDLLQNILSKLPAKSFASAACVSRNWNQISSRILLHPNFI
SAFSLNVSLSEAVNEVVGKVLSKPTKPHFGILSICSEFDLDEAHALVVGKLSSRIPIVTC
DCGGIIGRNAQTDEFAEVKFGYSDTSLPAFTAGISLTVGYLPGLKVDAVPLLDTSQGASI
DKFLMKLRDFSASVSGLTSPEAIIMFGDSKADVQPLVEKMDCTLSQQTVIAGNERCCFRH
SSIDNTENFLTNRGKKPHDDAVALVFARDRTKLDGVGKIEFHFAVGAGVSTVGPCYKVVS
AKMRKLEFTTWLTAKREGENEILDGEEMLNDFELEMGEPASMYDLYIGVRKRRKYSIGSK
QVKSVTSVAYHHVIEGDEQDLYVEGWDIKTGDAFYFHVPDLSFALNSCASVSENIGKLKH
KEMIGGFVFACCGRGETFFEKPNVDSSPILDNFPEIPLAGMFCGGEIGRGSPDLGQSDDK
GQEEASRDSLLHVYSSVYLLMSYNPPTCRP
>Sgl45902 E3_activity/RING/RING 32.7 10.9
MYVASMRKSFKDSLKVLEADIQHANTLASEFPREYDGACLQMRMSYAPAAHFLLFLVQWT
DCNLAGALGLLRILIYKVYVDGTTTMSTHERKASIREFYAVIYPSLLQLQSGVTDNEDKK
QKAACTERYRKRDEEEYRQYTDLDVEREDECGICMENYSKIVLPNCNHVMCLKCYREWRS
RSQSCPFCRDSLKRVNSGDLWVFTDSRDVIDMLTLTKENLRRLFMYIEKLPLIVPESLFD
AYDSHLK
>Sgl45930 E2/UBC 95.9 0.0
MEPFGDSDVESFSETSSDYQDDIFSMYSGHAQSILSSLEDSIEKIDDFLSFERGFMHGDI
VRSTGNSTGQMGKIVDLKTYVDLESVFGEVVKDVESGKLSRMRSILVGDYVIHGPWLGRV
EKVVENVCIIFDDGTKCEIMATDQAQLLPLSPNLLDDSLYPYHPGQRVRVCHRTGSTSAG
WLCAMSKKNQHEGTVFSVEVGLAYVDWISSAMVGVSMTLPPPCRLQDPKSLTMLSCFSHA
NWQLGDWCILPSENRLQKSLNTNIDDIFSILKKKIKFDVMWQDGSISLGLDSHSLLPVSV
LNGHDFFPEQFVLEKTSSDDLVSPVSRRWGVVRCVDANERTVKVKWESIGGVTEDTDEEN
MEETVSAYELVEHPDFSFNIGDIVFLSDNNYFVDQLNKMRIEDRTVLGSEGRAVDLSETQ
KRCFLSCIGYVFGFRNGNVEVEWASGVTTKVAPCKILRMEKDDGSVATHILPEQNVTEYN
DGMPDYESQSVHHQDSSDNSSNAAADSQSSHRSSHFFSLSQAAMGFFTSIAGNFFKQNGS
TTLPQHMSCTHAIDESNIGSFDVEEDIIESCVMFPDTQVMKMTEFDAYGSISLKPKVNDN
EENTELLSVVKPKGLKQFKQFDIVGDCSDHHFANAEGKGAALSQMKKGWLKKVQQEWSIL
EKDLPETISIRIYDERMDLLRAAIVGAPGTPYHDGLFFFDIMLPPDYPHVPPLVHYHSGG
LRLNPNLYESGKVCLSLLNTWTGTGSEVWNPGSSTILQVLLSLQALVLNEKPYFNEAGYD
QQIGRAEGENNSVSYNENAYLGTCKCMLYLLRKQPKHFEALVEEHFGKRSQHILSACKAY
MEGVPLGFGSKAENEKGNSMGFKIMLAKLFPKLVQAFSEKGIDCTQFAEPGK
>Sgl45950 E3_adaptor/Cullin_RING/DCX/DWD 95.6 8.5
MGSNNEWDAEEIFQKYLHDYLVKNNMHKTAEVFAKEANADVCAVVSAIDSPQGFLAEWWS
IFHDVYFHLHPRPAETGQKESPKGKQVTGTSSQGPCVEEPKYGITPQSSAHDCDSILAQK
SSKIREGANQKRMAKKFDSSSQTSTETPSRSKLAGCPSNSQRNPRKPAQQRQDKKRVATL
GSTPMGLSTYAEPKTIGLESKLTSAPLKGWPLIGGNQVPPRLGNQVLDSYLQSANTQKLV
DLSMSQTQQEIYAQFLANTPSKTLSSFPLTSDLDILFRNGIDRLSGQDGQDESIEMFFTQ
YEDQADCANAPSTLQHPSNEKNGHTGVSLVEIGSLHASKGKVFSCNFSPNGNFLACAGLD
KKVLLWNMNTMSYTSSLESHAHLITDIRFHPSSKFFATSSFDKTVQVWDASEPRKSLFTL
SGHDDHVMSLDFHPRNMELLCSSDSNNEFRLWDVKGYTCLRVSKGATRQVRFQTQLGRLL
AAASGNVVNIFNVETGNFEFSLKGHQGEVRSICWDVTGTYIASVSEESVRLWSILSSARC
IHELNSTGHNFQSCAFHPEHPLLLIIGSYQLLGLWDPTHSSTIDTIQAHNGQIASLSSSP
SAGLIASASHDQSVKLWR
>Sgl45967 E3_activity/RING/RING 25.3 8.2
MPAQKWSQNEDPPQNDAGNHDEQLEEDDDAVVDADVEEEDKVEVEDGEEEEVDDDDDDDD
DEHSDGDGGGDDDNEEEDEDEGEGEGEEEEEEEEDDEHGDGEAVDRSSSHSSDIEDDEED
RFIVIRLSDIRKEVQCPICLGIIRKTRTVMECLHRFCRECIDKSMRMGNNECPACRTHCA
SRRSLRDDSNYDALISAIYPDVDLYEEEELAFQEDEKARNKQIQSAIAQTVQRQTEALSR
KRRRSQGNHRRRRNYRSEDEDDVNGHDGGKDSSSADERGTEPKPKRPKRWRGQPLPAAVS
GDGAGNEKDQEVQREAGVSPAAFVGTSEMLVWGKGGIRSNTRYGSGSGGNGKHSRSRLSR
LSEHLRNSDKNDDELDINVVLVSLDKEKEPLLQHPYLCGRPALSVGQLCQFIAIETSLPP
EKVEILGVKGLCATLSTLQAKTSSSTAFDACKDELQVLDAKETLAELKAACNFARGQLML
AYRLKLT
>Sgl45968 E3_activity/RING/RING 17.4 9.0
MMLVQFHLQERSDEDHFQIDIVDHINEEDGDVEIVEEDDVEIIEDGDVEIVEEDGDVEIV
EEDDVEIIEDDDVVIEDENVDEEVVTPVNDKVTTQSFLNKCDNVNEEGYIMVKVSDIRKE
VECPICLGIIRNTRVFKKCIHRFCQECIDKSMRLGNNECPKCREHCASRRSLSNDPDYEA
VISAIFPDIDQYEEKELAFQEDDKARNKQTQATIAQANLRQKTRDKKQRRSKKKNHGRRN
YQSSSEDEDDVYGHGDGGKKCKAETSLAPASVDEANDTNMLENSLTRVSTEFFGTTSNSP
LLVWGKGGIRSSIARHGSCSNGNNNHPQSRLSRLAEHLQKSNINEDEMDIHVILVSLDKM
KEPFLDYPYVNGRPTLSIGELCQFISSRTFVPPDKVEIWGVRSISSKVSSLSTVELQSLK
SIAVDASKDGLQILDAKETLDGLKATSDFARGQLVLSYRLKLE
>Sgl46157 E3_adaptor/Cullin_RING/SCF/F-box 15.4 0.0
MDHVETNCKLPEDLFRDILSRLSVRDLLRFRSVSKSWCALIDDPSFILTHHFIQYAMHKA
NGDVPLLLWRHIGSIRGYQTECYLFFKQQGYDTISNWTSDVERYAHSVSPSDPNINLGIF
CRGSANGIICLDFQGTDLKVTGRDFYYISLWNPAIRDFKIVAYPHVADQRMPGNFVVVGF
GYDPVTNDYKIVATTVVSSDIVLVYMVYTLSTNSWKRVNEPSLFGSNASVRSSLMDSCLN
GVYYWTAHLLNNIEDKIFRILSFNFSTEAFIFSDPPQEALPHVYLMGNEFYWNIGLYNER
LALFLIHPALDTPESSADIWVATEFDDEFGVPVAWQCLISIKPIFERIGSTFGAQWVDGD
IVFQLFPNEFCLYNPTTGKFRRLGISFRHCFSYVESLFPLSRRVA
>Sgl46158 E3_adaptor/Cullin_RING/SCF/F-box 15.9 0.0
MDHVETNCKLPDDLFRDILSRLSVRDLLRFRSVSKSWCALIDDPSFIRTHHFIQYAMHKA
NGDVPLLLWRHTGSIRGYQIECYLFFKQQGYDTISNWTSDVERYAQSVFPTNSDINLSIF
CRGSANGIICLDFQGIDLKVKRRDFYYISLWNPATRDFKIVVYPHVADQRMPGQFVVVGF
GYDPVTNDYKIVATTVVSSDIVLAYMVYTLSTSSWKRVSEPSLFGKTASVRCSLMDSCLN
GVYYWTAHLLNNTEDKIFRILSFNFSTEAFIFSDPPQEALPPVYLMGNEFYWNIGLYNER
LALFLIHPALDTPEASADIWVATEFDDEFGVPVAWQCLISIKPIFERIGSTFGAQWVDGD
IVFELYPDEFSLYNPTTGKFRRLGISFRQCFSYVESLFPLSR
>Sgl46166 E3_adaptor/Cullin_RING/SCF/F-box 14.9 0.0
MDHVETNCKLPDDLFRDILSRLSVRDLLRFRSVSKSWCAVIDDPSFILTHHFIQYAMHKA
NGDVPLLLWRHIGSIRGYQTECYLFFKQQGYDTISNWTSDVERYAHSVSPSDPNINLSIF
CRGSANGIICLDFQGTDLKVTGRDFYYISLWNPATRDFKIVAYPHVADQRMPGQFVVVGF
GYDPVTNDYKIVATTVVSSDIVLVYMVYTLSTNSWKRVNEPSLFGSNASVRSSLMDSCLN
GVYYWTAHLLNNTEDKIFRILSFNFSTEAFIFSDPPQEALPPVYLMGNEFYWNIGLYNER
LALFLIHPALDTPEASADIWVATEFDDEFGVPVAWQCLISIKPIFERIGSTFGAQWVDGD
IVFQLYPDEFSLYNPTTGKFRRLGISFRPCFSYVESLFPLSRRVA
>Sgl46312 E3_activity/RING/RING 31 4.7
MDVCWLSFGSSFSQLKFVLFEKVVQLLQCMQNRAFGFQFALKLLNYVALAIGTIIFAFGG
VIVGGIAGAIKGQTTESGLCRGASIGFLSGAIVALELLDSLLNGHFHTKVALFGSIFDGK
AFREWVSPAVLKAYQWQTSMNEGLDNEEGSDIYNIVEIRGMCPEQIKKLPVINFSCTSSN
SSSLPISHNEVCCTICLQDLVEGEKARKLPGCEHLFHMMCIDEWLVRSTSCPVCRNNVDL
FDYLGCENVL
>Sgl46322 E3_adaptor/Cullin_RING/SCF/F-box 17.1 0.1
MATLFPQEIEEEILKRMPAKSLHRMKCVCKTWNSIICSPSFISSFNRRNSHNPKLLLLKH
PHPHRLPPNSATNIHFSVSSDSFVELHSIKVPQQINNGDDDLRPIRVELVTSNSINGILC
VLVYMGLSNGKLMNCEMFLWNPSTRETMTIPSSEFSGLFSGVPMVKFCCGFGVGFNRDDY
RVVRVSYLNTIKPTTEVYSLRNDRWMDLSLLPRSGISSNILWASSTCTFVDGAGYWGAFS
SESKDEFFVLGFYFACSYFRKINVPEECVDGRDLRYHSLWVYEGMLAISVLRFAEFESDI
TRHYIWVMKPGRTLGSPNWCNMFNIDLVGGPRKPVLTLGNGEVLLLGEDDGEHALYDPVM
EEVKRVDISDVDTVISYTESLVSLSKLMPQDGVAVSYG
>Sgl46324 ULD/UBL/ATG8 160.2 0.4
MAISSFKFEHPLEKRQAEAARIREKYPDRIPVIVEKAEKSDIPDIDKKKYLVPAELTVGQ
FVYVVRKRVNLSPEKAIFVFVKNILPPTAAIMSTIYEENKEEDGFLYMTYSGENVFGLRG
LH
>Sgl46363 E3_adaptor/Cullin_RING/SCF/F-box 14.1 0.1
MAVSTMDVDRISSLPLELKAEILSRIPSKSIFHMRCVSKNWESEIKNQVFIHLYVQCQLG
LNFGWCFEESPTMVMLLGDDSLYSYDFETDVQYRHRHSPPNLGGSLKAQLIGSCHGLLCF
QESCCRFSLYNSATRSYATLPTLGHEEFIKCTTKRDAGFGYDFTSNDYKVLAFDTIIPTN
NDLEAYYLTHIYSLKSNSWRKIKNMPRGDSMVYLKNALHWVTTSYREEEEDQIPVIIAFN
LGIEDYYELQLPSTAGNSTPSVYDSNLTALNGCLHMGDYTPWDMNMTIWVMKKYGVAKSW
TKLVQSTIFDNEPWRLRPLPYTYLKSETQILVGLEAYPERFVICDIQSQELETMLRIQVP
TEELHAEESDDEDGEGDGEVDGGFFVVPLPTSLACVDPLLPIIVRTKYFSMQNIKMTLLL
GDSIRVLELKKELRLLMKAITDEEDNQIHTNNYHNNNDFVSNLSSSSFFDTIDKVKDLSA
LQDVKLKRMTSLRLYDDTLSCPLSKQLMKDPVIIISTGQVHPHHSKKSNNLTRITWSGEV
EAK
>Sgl46369 E3_adaptor/Cullin_RING/SCF/F-box 13.7 0.1
MDVDRISSLPLELKAEILSRIPSKSIFHMRCVSKNWESEIKNQVFIHLYVQCQLGLNFGW
CFEESPTMVMLLGDDSLYSYDFETDVQYRHRHSPPNLGGSLKAQLIGSCHGLLCFQESCC
RFSLYNSATRSYATLPTLGHEEFIKCTTKRDAGFGYDFTSNDYKVLAFDTIIPTNNDLEA
YYLTHIYSLKSNSWRKIKNMPRGDSMVYLKNALHWVTTSYREEEEDQIPVIIAFNLGIED
YYELQLPSTAGNSTPSVYDSNLTALNGCLHMGDYTPWDMNMTIWVMKKYGVAKSWTKLVQ
STIFDNEPWRLRPLPYTYLKSETQILVGLEAYPERFVICDIQSQELETMLRIQVPTEELH
AEESDDEDGEGDGEVDGGFFVVPLPTSLACVDPLLPIIVRTKYFSMQNIKMTLLLEEETD
LARTSTRHNIRMAMYWLVGGCSLGTPCFFIIQAMVETIWPMDFETEGMIIDDEVNVALVR
PLPHGVKLHAIVDEEWNKMRKKKGME
>Sgl46385 E3_adaptor/Cullin_RING/DCX/DWD 91.9 3.6
MCLFMCSIEFDRDHELFATAGVSKRIKVFEFSSVVDEPEEVHCAVVDIPTRSKLSCLSWN
KYTKHCIASSDYEGIVTVWDVATNQSVGEYEEHEKRAWSVDFSRTEPSLLVSGGDDCKVK
IWCTKQERSVLNIDMNANICSVKCNPGSSMHVAVGSADHNIHYYDLRNISQPLHVFSGHR
KAVSYVKFLSTHELASASTDSTLRLWDVKENKLLQTYRGHINEKNFVGLTSNSEYLSCGS
ETNEVFVYHKAISKPVARYKFNRSELYDADVERGSHFISAVCWKSDSQVIMAANSQGNVK
LLALTA
>Sgl46396 E3_activity/RING/PHD 36.7 7.1
MAKTRPGKRDLDSYSIKGTNKVVRVGDCVLMRPADVGKPPYVARVEKIEADSRNNVKVRV
RWYYRPEESMGGRRQFHGAKELFLSDHHDVQSAHTIEGKCIVHSFKNYTKLENVGADDYF
CRFEYKAATGAFTPDRVAVYCKCEMPYNPDDLMVQCEGCKDWFHPSCMGMTIEEAKKLDH
FLCSDCVAEDDPKKGDSTFSASPLADGKPDNKRRKR
>Sgl46398 ULD/UDP/UFD/UBX 48.8 0.0
MASKDKKTSRSVSGGSRPAGGIRTLADLNRRSTPDSDSDSDNAPQEYYTGGEKSGMLVQE
PSKGNDVDDIFSQARQLGAVEGPMENLLPSSSRSFTGTGRTLASGDAVASATSPPESVVH
NIVFWQNGFTVNDGPLRRLDDPENATFLESIRKSECPKELEPEDRRSQVHVNLIRRETNC
PEPEVRTVPFQGVGRTLGGSTSAAVSDQTPAAPLNSAPPPSAGLVVDENQPSTSIQLRLA
DGTRMVAHFNFHHTVNDIRTFIDSSRPGGSRTYQLQTVGFPPKPLSDLDQTIEQAGLANS
VVIQKL
>Sgl46405 E3_activity/RING/RING 14.7 11.9
MSTVATRSPANQDRPLLLQPPRRSSDQRRIRTLLDLLTIEKTDGGDRTGRQSEEEINNNN
NNSSSNNISRWKVLRERLGLKVVGCCGIVTWGYDGNSNSSPLEEQNDVVQQGEEGEEEQS
MTRQQENEEGMNLAAALAAERQFRAVESSGGYGVDEDGGLLATPSRVSLMRLLEETSDGC
DLERERSKGGGEEGSESGSIGGGGGDAVCCVCMGRKKGAAFIPCGHTYCRVCSRELWLNR
GSCPLCNRRILEILDIF
>Sgl46412 E3_adaptor/Cullin_RING/DCX/DWD 84 4.4
MVETSIAEGAIVPHLKPDSDSPHSTDDLNTNNNNNNNNNNNDNDESISCDNDFLCPICMQ
IIKDAFLTACGHSYCFMCISTHLRNKSDCPCCGRFLTPKLIFPNITLDKILKKMSNHQFT
ESASSTEQLRRALVQGCNVSVKDLNCLLSLLAEKKRKMEQEEAETNLQVLFEFLICLRKR
KLEELSQIQNDLQYIDEDIDAVQKRKTDLLNETKSHLRLGVRGDDADTNGICSIVPTPVR
GGGSVAQQARFSENQHSGRDNEVVPCSREFIENVDHTSLGLQQLAPDEGFKTRKRQVEAQ
FTDLQECYLQKRRLGAKQKQATETRDLNNMNSLGYHAGLVDFQSVLTSCTRYSQLRVMSE
LRLGNVFHSANIISSIEFDRDHELFATAGVSKRIKVFEFSSVVDEPEEVHCAVVDIPTRS
KLSCLSWNKYTKHCIASSDYEGIVTVWDVATNQSVGEYEEHEKRAWSVDFSRTEPSLLVS
GGDDCKVKIWCTKQERSVLNIDMNANICSVKCNPGSSMHVAVGSADHNIHYYDLRNISQP
LHVFSGHRKAVSYVKFLSTHELASASTDSTLRLWDVKENKLLQTYRGHINEKNFVGLTSN
SEYLSCGSETNEVFVYHKAISKPVARYKFNRSELYDADVERGSHFISAVCWKSDSQVIMA
ANSQGNVKLLALTA
>Sgl46455 E3_adaptor/Cullin_RING/SCF/F-box 17.1 0.1
MMKFQVFGILLFLIIYTLSYPSLLVFSSSSLFPNSSSSFSSSQLCHHHDKVALLHFKNGF
TIDPQFYEWYPIIQYYGMSSYPKTKSWKEDRDCCLWDGVTCDTVSGHVIGLDLSFSQLRG
VIHQNSTLFHLSHLQALNLAANDFYASHISPNLANFTSLKTLNLSYSAFTGDVPINLGLL
SQLISLDLSRNYPLEMPNFDKIMRNLTSLRELILSGVFFNSAFPQAVANLSSLSSLDLSV
CNLQGSFPSNIFTLPHLHSLKVGKNDNLYIDASHFSNLSSSLEFIDFSYSSKLTGKLPEY
SLGSQPPQLRTFLAQDCNLYGSIPMWIWNTTDEINLRYNSLSGKLPSSVNTKHLSGLTSL
YLEDNLLNGNIPSWLMNLPSLKSLTLHSNQFTGEVPEPFPKGNCLLEDLFLGYNNLSLQF
NFLSNCNNLKRIDLSHTSLIGVNNPPLIWPNLTDVDMSSCNITSFPNFLHYSKLPLLQYL
DLSNNKIQGEIPTWFYNVGKDSLNGLNISHNNLTGGLHLRSWKNLDQIDIRSNSLQGLLP
LPPPNTTLFLASNNKFHGEINSSFCDLAMLYALDLSYNHLNGTIPKCKLFRGGLEVLNLR
SNRFRGVLPLNFTNDCILESMSLNDNLFEGKVPRSLKRCKALEVLDLGNNQLNDTFPHAL
GTLPHLKVLVLRSNHFQGLIKYHPKAHIKPFPKLQILDISRNQFCGNLPTRYIENFKAMM
VSNNVGANNNSDRYIGVSNDYSDYYHDSLVLTVKGIELSYERILSILASFDFSSNNFSGD
IPNSVGQLVTLIGLNISHNNLRGHIPPCLANLSSLEFLDLSCNELEGEIPPQLVRLTFLA
VFNVSNNKLDGPIPQGSQFSTFTNESYGGNLGLCGDPLPKCGEHDHQPTTPESQQEGSNL
IDIITSISLCEIILLGFGLGTVLGSSIGYCMLSARKSNWLSRKADRYIIEGXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXLDYKKLIWYNLNKKTVRHVNISGLPESFDTEVFYKS
LVDPGNLIPRQKKQSVQSCNFLAVFPEKLLSHVLSYLPIKTLLRFQCVCKKWYNLINDSE
FIKMQLEVSSNCNSSSLLILGGEKLFSLDFQLLDDAMKVIHSRVCPDGLTNIVGSSNGLV
CLHKDSDIALWNPWTGKYERLPPANFQFHVSSGMYYCFIHGFGYNPTSNDYKVICILQLH
NNLKGGSVHSEIHVYSLRSKSWGTTRKFPYIICYPCSGVLASGALHWVARQNPELYSSSN
LLIAFDLGSEKCRVVTQPNYIDTDFHMSLGLLRNSLCLLCHYPKQSVDFWVMTEYGTESW
TKLFSISQPKLIKQFEYLKPLGYSNDEAEVLLEQDNEKLLCYNLVKNTIRYVKVRGLPTS
FEAVMTCGSLVQIGSPPKNFHEKAPNKSQSVKAKVRDGSDTFLAKGFKLKL
>Sgl46456 E3_adaptor/Cullin_RING/SCF/F-box 13.2 0.0
MILPFGFPRKKFDQLILTTIFDHCDFCIFELRFCFGGGEVKMMVDLPTPLIMDILSRLPC
KTLLRSRCVSKSWKYLIDDTHFISLQLKRSMENTTNHTLLLRDCYIYSVDFPKLDEAVVI
DHPLKSYSIGTDLVGSCNGLLCLSNGEGKQMNGTIIYNPTTRKRWELPVSRFKFPENAFC
VERTVYGFGYALGSDDYRVVRIIQFFNSYPDFYESEVKVFSLKTLSWRRVQDFPHECYLT
FKRQRGIYVNGCLHWIVTFKPESDGSKQILAFDMDSEDYKVVPLPKYSPGEVHLNVEVFQ
QLLCLLVNYPTIRSEVWVMKVYGIEESWTKLFAIVQDDVIGPFGYVRPLAYSKDGSKVLI
EPDLGKLIWFDVERQKVETVKIRNMPTNPEITVFVESLVFGSRKTHQRNKRSNERKRLEN
ANITAMPNSSAVISGGPLDDVHNDTRNSDKGQQTLNGNHNPRKKGQRDNMGGFLSKGFKL
KL
>Sgl46457 E3_activity/RING/U-box 114.2 0.7
MIASWRRKRAGRGADGGSKRKLSELIVPSHFRCPISLELMKDPVTLSTGITYDRDNIEKW
IEAGNVTCPVTNQVLKTLEPIPNHTIRRMIQDWCVDNRSHGVERIPTPRIPISSDEVGTI
LEKIETARAPNECQELVGKMSKAMKESERNKRCILENGASKSLSLAFQTFSETEGETVIS
LLEEIMSVITSMTPLEAQAQGSLRTPKSLGRLVWFLRRGGLSGRRSAVLILKELVSTAKD
QGKLVESLVAMEGTIEGLVKLVKEPICPSSTKASLVVIYNMITSSSSHVHASSSNKNIVI
GKFIEMGLMTLVLDILVDAEKSISEKALGVLEGLCRSREGLEAAYDQALMVPVVVKKILR
VSDLATEFSVSILCRLCENEGREDGGVIVEALQVGAFQKLLLILQVGWNINERIKEKVTK
LLKLLNLYRSKIECIESTDFKDLKRPF
>Sgl46502 DUB/USP 140.4 0.7
MGSKRDREEQTDGEVKRQKVEEEKESDSPKMHAFENPLLPLASYDDDEEEEERRREAIRR
RGVEENAKNAELNGRVNEVYDDDDDEEDEDDANFNQGKRNRSVEVRRDCPYLDTVNRQVL
DFDFEKFCSISLTNLNVYACLVCGKYFQGRGPKSHAYTHSLEAGHHVYINLKTEKVYCLP
DGYEINDPSLDGIRHVLNPRFNREQVQQLDKSKLWARALDGSDYLPGLVGLNNIKETEFV
NVTIQALMRVTPLRNFFLIPENYQHCKSPLVHRFGELTRKIWHARNFKGQVSPHEFLQAV
MKASKKRFRIGAQSDPVEFVSWLLNTLHTDLRSSKKNTSIIYDCFQGELEVEKEIQSKGV
VDRRENGDDQNGGSENPNVVRETFKMPFLMLGLDLPPPPLFQDVMEKNIIPQVPLFNILK
KFDGETITEVVRPQLARMKYRVTKLPPYIILHMRRFTKNNFFVEKNPTLVNFPVKNLELK
DYIPLPPQKEVKKSRTKYDLIANIVHEGKPNEGTYRVFVQRKSEEQWYEVQDLHVSETLP
QMVALSEAYMQVYELQQQP
>Sgl46503 E3_activity/RING/RING 30.2 9.8
MEKVANVSVEDAHVKNLRLFKCSNFKQEKDGFILFKIFKTDYLGRPGTRTELIREWEPNY
TGISFCAEFFRFLYDEKLPLNEDEDHVFQTVKATNCFGLEVTRVLTQEICGFFRSCFGLY
EDTLLGIDHGCPSSKNDFLLIIVVDVFITTVSLDYLDAKLTMLDEQNRVLPKGDDQANEV
KNNSCGDDMMNSNNMVHNDEDNDHISKAHSSSDVVHVDMEYVDDDDDDDDDGDSEDEGDD
MNKATTSEECKDVHVDNIDDDDEDDCVCVEEQNEECFDDVIDCVKYWKKTQDGEEEPIIV
FEMKPLLTIQEMELDLMEDGNYKLLIDTTNNKLVGDECSICISGLTESVPKSSIFPWFPR
MNSWCIVKLDCGHVFHHHCIFKWLARTPSCPLCRSSSIVTV
>Sgl46509 ULD/UDP/UBQ/UBQ_Other 41.9 0.2
MKRGGMLLNGGVLYMWVGFFGGTASYRRPSKRKLEELCDACNSLPIRRNSISNFAGNSVI
DSRFQSIPAGNSECKHVNSDSTTFEIQFFVRMLSGETLVMRANLEDTVETVHRRISERKK
IGVDVQRLLYNGKQLQLQETLKNSKIKNDAMLHLVGRMQSTDYPKVWRILCDLNSIIGRI
CKKELPFADPSPVKYTMQQFMALRLDQDISLMVAFGRQFYHEKRRKLVQSGGIINKYDFC
QIFMDACAPQSLIALYMLGNKIYKECAEECIKSFVDFVKAFEGTWIERAYCAKPVLEFCK
SLRMMVKEDDHLYIHCRSVLGSMLAKVEVIKWPEDVSDVHDYVHDYVVGTDVFPFVKELG
QTLLKDLVQSVESDSDGPLYRDVCDFSALLQPVLSLIGMQPPAAANSLRTEGNYKLVTDV
RDHIRLIFTNFLSWVDKGLHKVKLSLFMKKKKGVVASTGGWSQYLAILKILHSISHFYPG
SQDIFWTIVRLHKTGVCSLILNYAERANDNSWLLQQRDILDFDSRRHLSLLLFPEVKEDY
GDMLEMLIDRSNLLAESFEYMRDASSSSLHAGIFMQFKEEVATGPGVLREWFCLVCQAIF
DSRHALFVSCPSDRRRFYPSPGKSFVVCASKVQPQYLEYFKFSGRVVALALMYKIQVGVV
LDRVFFLQLAGRHVSVEDIRVADPFLYGSCKQILEMEAAFVDSDVLGLTFVTEEEELGAR
KVVELCDGGKDIAVNSKNRKIFVDLIIKHRFVTSIAEQVSYFASGFSDIIGGDDLKKTFF
EILELEDLDWMLHGSESEICVKDWMSHTEYTGFRKTDPQIIWFWEVVETLSAQQKKMLLF
FWTSLKYLPVEGFRGLASQLYICNSKESEEFFPSSHTCFYQLCIPPYPSKDVMQQRLLVI
TQEHVSSSFGSE
>Sgl46510 E3_adaptor/Cullin_RING/SCF/F-box 15.4 0.0
MTELMDLPIDLTINIFLRLNAKPLMQFKSVCKLWYYLISSPRFEELHLDQTLAQSNPKLQ
FVFSAPYLSSAEFDTFDRICELDNPFRIQGFAHVVGSCHGLLCLTNYDLHLTIVLYNPTT
RTHKRLPFLPKPSSLSHRYSFGFGYDGVSRDYKFVRILQSDEGMGPFKSQVMVYSSKMDS
WVRAPDVPCPYFSYREDGVFVNGTLHWIHESLLKDVKFFRIVGFNLEIWIMKEYGVVESW
TRLYKVKQSQRLMFLEWPIAYSLNQQKLFLQLNTWRVVSLDLQTMVLNDIKVCDFPRCFD
TRVCIENLTMLKDTGSEVLEIDHQQEKKRRRRGKDMHQRRTISVDDILDEHMEE
>Sgl46580 E3_adaptor/Cullin_RING/DCX/DWD 58.1 12.1
MDVTNWDEDAYRNTILEERGLEYRTVFRAIFGPSSTSNPNSDIVVSASSDGSIAAYSVST
ILSSHELCNGISNSQKVPAVQPNCFLQAHQGPAYDVKFYGDDADALLLSCGDDGRIKGWK
WKELEFSDTTIHVQGSHVKPIIDLINPQHRGPWNAMSPISENNAIAVDHQGGSIFAAAGD
TCAYNWDVETSKIKMVFKGHSDYLHCIIACKGSNQIITGSEDGTARIWDCRSGKCVQMIS
PERSKGLKELSSVSCITLDASESWLAYGSGQSIFVWNLLASQQISRICTPTTCQDVVFDH
NNILAVGSSPILARMDINGKILSQIRCAPESAFSVSLNRSGVVAVAGYGGLVDVISEFGS
HMCTFRSTSTRAEQAS
>Sgl46585 E3_adaptor/Cullin_RING/BCR/BTB 36.1 1.2
MESRTAFSDSNDISNGSSICCIPNNTGTVTGTGTTTPTPDTADTAALCRLSENIQSLFHP
ESESESFSDAKIVVSGDCREVSVHRCILSARSPFFRAEFSSRRKDKDKDKDNHKVELELK
DLAGDIDVRYESLVAVLGYLYSGKHTSNNLPHSVRVCVDDDCTHLACRPALDFALQVLYL
SHKFEILELLALYQRHLMEMLDKAAPDDILIVLSVADMCGSACERLRGRCIDLAVRSNVD
VTSLDKTLPQDIVKQIIDSRKEIGLTDPGYVEFPDKHVKRIHRALESDDVELVRMLLKER
HTTLDDAYALHYAVAHCDAKTTAELLELGLADVNLRNLRGYSVLHVAAMRKEPKIIVSLL
TKGAHPADITSDGKKALQIAKRLTKAVDFYKPTEQGKASPKDRLCIEILEQAERREPLLG
EGSVSLAKAGDDLRMKLLYLENRVALARLLFPMEAKVAMDIAQVDGTSEFTLSKNMADAR
RNAVDLNEAPFILKEEHLQRMKALSKTVELGKRFFPRCSDVLNKIMDAEDLSQLAFLGND
TPEERQRKRKRYLELQDALTKAFSEDKEEFDRSTLSSSSSSTPLGRPYGKTNFRR
>Sgl46603 E3_adaptor/Cullin_RING/DCX/DWD 91.5 14.5
MRGKNQQSAVDEKYAQWKSLVPVLYDWLANHNLVWPSLSCRWGPQLEQATYKNRQRLYLS
EQTDGSVPNTLVIANCEIVKPRVAAAEHISQFNEEARSPFVKKYKTIIHPGEVNRIRELA
QHNHIVATHTDSPDVLIWDVETQPNRHAVLGASPSRPDLVLTGHKENAEFALAMCPKEPY
VLSGGKDRSVVLWSIQDHITTTASDPSSNKPQGSGATIAKPNGESPSVGPRGIFEGHEDT
VEDVQFCPKSSQEFCSVGDDSCLILWDARAGSDPAIKVEKAHNADLHCVDWNPFDENYIL
TGSADSSVHMFDRRKLTSDGVGSPVNKFEGHKAAVLCVQWSPDNPTVFGSAAEDGVLNIW
DYEKVGKKKEHDVTAPNGPPGLFFQHAGHRDKVVDFHWNAYDAWTIVSVSDDCDSSGGGG
TLQIWRMSDLIYRPEEEVLAELEEFKSHVATCGSKSEVRVIYYYNLVLLKILLFLLLPSI
RFFVLFIRFTFSCRYLRFFNSMLQQQAVLCSLQPSIKNVPFFSSQIPTSSSSLGLSMDYN
KFVSSSSFKSDYCNKLPFVSCKASIDAHNSSIKNENMPLPVHGVSEKVVGVLGGGQLGQM
LCQAASEMALKVAILDPKENCPASSLAHYHMVGSFDDSATVEEFAKRCGVLTVEIEHVDV
ATLEKLEQQGVDCQPKASTIRIIQDKYLQKLHFSQHGIPLPEFMQIDNFESAKRAGELFG
YPLMVKSKRLAYDGRGNAVAKSEEDLSSAITALGGYERDLYVEKWAPFVKELAVIVARGR
DNSILCYPVVETIHRENICHIVKAPAAVPWKIRKLATDVAHKAVSSLEGAGVFAVELFLT
EAGEILLNEVAPRPHNSGHHTIEACYTSQFEQHLRAVVGLPLGDPSMKTPAAIMYNILGE
EEGETGFLLAHDLMRRALTVPGASVHWYDKSEMKRQRKMGHITIVGSSMGIVDGHLKSLL
KEEKPADAIAPRVGIIMGSDSDLPVMKEASRILNMFEVAHEVRIVSAHRTPDVMFSYAKS
AWERGIQVIIAGAGGAAHLPGMVAALTALPVIGVPVRGSSMDGLDSLLSIVQMPRGVPVA
TVAINNATNAGLLAVRMLGVADSDLTSRMTQYLEDARDDVVVKADRLHKDGWEAYLNN
>Sgl46652 E3_activity/RING/RING 31.1 6.3
MGSSSSNLGSTSSPPPKHTKVNRTKQRLASFICGASASSTSEREDYAAGSVLNSADYSQQ
KANKSSSTINNSCSTSSMGTGFSSYSSPRSGAVSSSDSSNISSEFTSIQDSRVESSGKRK
CSSEVEEVVLPCTVNAERKHHQRRLADSVSTSSTGQSQHKGLSSNAHTDDLNNDMLQINS
EILSPTSLQHQEPEQPTVLEEVTEITGSQSSDSVVLPDVSDSGLASQSHGDEAIREAMPS
GLELFVSDRTEARSGSEESLLHVDLVSISSNLLPNINNETSTREARRNSRRMFRDAFSSR
SSRRNADFPAILFATEDSSLMGSHRRWLLDLGDDFFDDSVDAEPWRFGRRSRFTNDRRRN
SRSEFWDRLRGAATENPHRTSCPLDLHPRGSCTCEVDEEASALSSISRIILLAEALFEVL
DEIHRQPDSFSLSMLSVPAPESVVDSLPIKTYEKPSTADHADDADQCYICLVEYEKGDKI
RVLPCQHAYHMSCVDKWLKEIHGICPLCRGDVRGGATEVAASSSDSVLT
>Sgl46654 E3_activity/RING/RING 28.4 11.2
MAAGNKLPGVEAARRRRIHQSSSGSSFSSSSGTIIGSSPCSRRSSFSLFTPNSSSASSLL
QPRIRTYQDNDDEKLGHLARQAKERLDEKLRAQTKSLIRRKNSDLSEDGTSRRSEMNGRD
LRTEVYGSKKNGGAKKLMGWGKLGWKSGEQQECAVCLDEFRVGENLVNLPCAHRFHSRCL
VPWLNNHAQCPCCRMSIFSNP
>Sgl46655 E3_activity/RING/RING 29.8 9.9
MAGMLPGVEAARRRRVHQSNGSSTSSSSGIAIGSSPCSRRSSFSLFYPNSSASSLSQPRS
RTYQDDEKLGHLARQAKERLDEKLRAQTKSFMRRNNSDLSENGTIQRSEMSGRDLRTEVY
GSKKNGGAKKLMGWAKLGWKSGEQQECAVCLDEFRVGENLVNLPCAHRFHSRCLVPWLNN
NAQCPCCRMSIFSDP
>Sgl46668 ULD/UDP/UBQ/UBQ_PIM 73.9 0.2
MAHSANEVAGSNEAGNSGTSIEIKIKTMDSQTYTMQVDKQMPVPALKDRIASVTGVVTEH
QRLICRGKVLKDDQLLSAYHVEDGHTLHLVVREPNASSSGSLPADPAVDRSSNGNRGQYY
QVAPGIVVETFNMPGQGDRVLPDVSRIVSAVLGSIGITNPGNNNETTGTRDHAADRPGES
PILDGMADASRTQPEQSGMRSSNDRSRLHNAFGIPAGLSFGSLQAPVVPDALATLSQYLG
NMRQDFTDSGRTSGTDSGASLHGNGGSSTLAQSGSGPEGLPSPASLAALLSATRQMLGQQ
VEEFLLQLGRQLENQENITDPVARVTAQSGALRNGSLLHNLGAYFLELGRTVTTLRFGGS
PAEAVVNTGPAVFISPSGPNPLMVQPVPFQPGASFGTPLSGTLPSNSGTINSNGGGIVPR
RIDIQIRRVGPSAHQAEPVGSQQSSGQRNPTTNVSGEEQVNQSSNGTTGVPSSNNGPTVR
ILPLRSMMAAVPDLNRPPQESSGNSVGLLYPVVGRYSSIPSGNLSNRTGNQVSNEHPSSG
QPQSSPESTVQHNVEGAAGNGRVPASNPGQRESVSSRTIDINILSAGGVQNDQNTEGQIP
PGILQILRGLFPGGEFHVESVSSQGTGSGSAMEQERSSSAVAQEAEPTATEEGLFLSRVL
QQLMPLISLNSGTEQSGGYSGGASQQGDGLASSTVVEDHQAGTSRRDDDENPGPNPKRQR
RE
>Sgl46689 UBD/Alpha-Helix/UBA 49.2 1.4
MAAKLKIAGIWVGVLEIELKDYTVRMLREEIAKRSNCDAITVNLICGGRVLKDSDNELTD
VGVKNNAKIMATRINFAEGRTLQRELMAQEHRSSKLDRLKATVDRLAQRHADGSLPVEDY
NIELEDQNGQRVNMGCETDQKSIMMGLMLHSKGKKLVRKQLYKDALEVFELGEEAFSLCD
PKLIERVDNVSILQIDMVWCYFMLRDINLLSVAGERLAKAREGIERAHGKDASRVRLLQG
SHSIEVALYLRMELLEGVVAFHCGKLEKSREALTSAKMRFSKLEVKDETLSLLLSMGYDV
DEAKKALKMNGQDVQSAINFLVEENLKKIRKMEEDLQRQQEIREQKMYGKTPLGKAVDLQ
MLKGLSSIGFERELAAEALRRHENDTQKALDDLTNPELNSNIQLDIESKKRKRQQKHVNT
IIEELVSMGFERSRVTAAVDSHGTKAEALNVLLAQSAQPPPAAVDGILSSDSTPGSSNSP
NEDEGEEDEGPFAILDGQLGKVQEFELEHELVEELDRGNAYSDYDIDVCKEGEAINEYLA
LLDSAMNGGN
>Sgl46719 E3_activity/RING/RING 30.6 3.4
MGKRKRTGASTADYLPSSPSDSMPCSSGRALMLGEQNSSDPGDVSIFKNHPSGREIMDSL
GKQPNSQLSLNKHQQNLSRSMFLKRSRHHFGNQYARRNSSNYHKPSASYGISPFQDERLC
FKLGSRYSSDMGHHPDFSEFRERAFWRPERIRSSSSVIHAVSADGARMGCGTCQKSLRRK
PHQLGSNPSPEELSIVAVLVCGHLFHADCLEQTTQLEDRRDPPCPVCSGFVPKAEPT
>Sgl46724 DUB/USP 266.4 0.9
MSRIKNISVPKPCPHLAEFKSKHGSNSFRDLQNLIRARPMGRASIYRAENEPSYCPSCSS
RPHRRLYACITCAGVSCYVHARLHPHPIAVDVDRAELFCWHCGDQVYDPDFDAAVLAAAA
PNLGEFVSLPPPLPLPRKRQKVEYCPREPAPTLEAVIVENSTSITQAGPGPGIDQGQGLM
LGPSLGLRGLNNLGSTCFMNCVLQALVHTPPLINYFLSDRHNRHFCLNRRNGGNGIGSGN
GNGNGKTRGRRGNGNEGKKMNLCLACDLDALFWAVFSGDRSPFSPAKLLYSWWQHAANLA
TYEQQDAHEFFISMLDGIHEKVKDQSKMQSQGNGDCCIAHKVFSGILRSDVMCMVCGFTS
TTYDPCVDISLDLEPNLFPKVGAQKSQKSCNEEADTMNFSFNNRTSTLTGCLDRFTRPER
LGPDQKFFCQQCQISQESLKQMSIRKLPLVTCFHIKRFEHSSSQNTARKLDRYVQFPFSL
DMAPFTSSSILRSRFGNRICSFVEEECQDVPDELSSEFELFAVITHTGKLNGGHYVTYLR
LSNQWYKCDDAWITQVSENIVRAAQGYMMFYVQKTFYYKASQTQMPS
>Sgl46743 E3_adaptor/Cullin_RING/DCX/DWD 97.5 24.7
MPAQKIETGHNDVVHDVQMDYYGKRVATASSDTTVKIIGMSSGSSTQPLATLTGHQGPVW
QVSWAHPKFGSILASCSYDGRVIIWKEGNQNEWAQAHVLQEHKSSVNSISWAPHELGLCL
ACGSSDGCISVLTARSDGGWDTNRIDQAHPVGVTSVSWAPATAPGALVGSGLLEPVNKLV
SGGCDNTVRVWKLENGTWRMDCFPALQMHSDWVRDVAWAPNLGLPKSTIASASQDGTVVI
WTVGKEGEQWEGKVLKDFKTPVWRVSWSLTGNLLAVADGNNNVTLWKEAVDGDWHQVSTV
EP
>Sgl46768 E3_adaptor/Cullin_RING/DCX/DWD 87.2 5.3
MSSLSRELVFLILQFLEEEKFKDSVHRLEQESGFYFNMRYFEELVTGGEWDEAEKYLSGF
TKVDDNRYSMKIFFEIRKQKYLEALDKRDRAKAVEILVKDLKVFSAFNEELFKEITFLIT
LENFRENEQLSKYGDTKSARSIMLAELKKLIEANPLFRDKLQFPTLRNSRLRTLINQSLN
WQHQLCKTPKPNPDIKTLFVDHTCGPPNGPNGARAPSPVTNTLMNASPVPKAGAFPPLGA
HGPFQSAPAPLPTSLGGWMANPSPVPHPAVSAGPMGLGVPNNPAAIVKRPRTPPNNNAAM
DYQTADSEHVMKRSRPFGAPEEVNNLPVNILPVAYNSQSHGQSSYSSLDLPRDVVMSLSQ
GSAVKSLDFHPSQQILLLVGTNMGEVMVWDLVSRERTAYKNFKVWELNACSMPLQASLAS
DYSASINRVIWSPDGSLFGVAYSKHIVHIYAYHGPNDLRNHLEIEAHIGSVNDLAFSYPG
KNLSIVTCGDDRLIKVWDAVTGAKQYTFEGHESPVYSVCPHHKENIQFIFSTATDGKIKA
WLYDNVGSRVDYDAPGHSSTRMSYSADGSRLFSCGTNKEGESFLVEWNESEGTVKRTYLS
LGKRSVGVVHFDNTKNRFLAAGDEFTIKFWDMDSVNLLTTTDAGGGLPASPCIRFNKEGT
LMAVSTSDNGVKVLANTDGVRLLRSVENRPFDTSSSASGAIVKGPTMGVFPAANAAVGAS
MGDRTAAVPAMVAMNADNRSLVDVKPKFPDESADKSKIWKMTEINESSQCRSLRLPDSIS
AMRVSRLIYTNSGLAILALASNAVHKLWKWPRNDRNMTGKSTASIAPQLWQPSSGILMTN
DLSETAPEDAVSCFALSKNDSYVMSASGGKISLFNMMTFKTMTTFMPAPPAATFLAFHPQ
DNNIIAIGMEDSSIQIYNVRVDEVKTKLKGHQKRITGLAFSNVQNVLVSSGADSQLCVWS
MDGWDKLASKSLQIPSGRSVNPLADTRVQFHQDQTHLLAVHETQIAIFEATKLDCQKQWV
APEARGPITHATYSCDSQSIYVSFEDGSVSILTASNLRLRCRINPNAYLSPNPSMRVYPV
CIAAHPSEANQFALGLTDGGVCVLEPLESEGQWGTPPPAENGAGTSNTVAGTDQPQR
>Sgl46769 UBD/ZnF/ZnF_UBP 91.4 8.3
MFTIRIHSVDINHPLFLSPPSNSNPIPNPNFIERRGIIHLFRNLDSHPSTSDSSSTTIQS
DLLFIVAVPNYFSSDDLLRFFGSYITDVSEFLIIRNDGMEDRYSVLIRTWSQDLADGFYR
RFNGMQFSPPEVEICHILSVLSMEFTELAEIASTPPSGYAELPTCPICLERLDQDTGGIQ
STLCDHSFQCSCISKWTYLSCQVCRLCQQQDDRPNCSVCDASENLWVCIVCGFVGCGRYK
EGHTFRHWKDTRHCYSLSLETQRVWDYEGDNYVHRLNHSKADGKSAMVDSHCMSHDGDCG
TCGHSEDSEMAGALYSSKVEAITDEYNHLLATQLENQRQYYESLLVEAKSKKEYTIAEAV
EKGVTTKMQDLQCRLEKYEEDKKAVLDMNRILMKSQEEYKKRMKEIEEREMKSLGSRDEQ
ILDLEEQIRDLKIYVEAQRKIGSITGSDNMKGGTLLPVPQTQSSPASAKRRTKTGRHRN
>Sgl46774 E3_adaptor/Cullin_RING/DCX/DWD 15.3 10.7
MSSSSIESKPWESMLPGPAGRNNGGASDMTSSGLLAFASGSSISLIDSRSMQLLSVLPLP
PPPSTSSYSTSLSLSPFVTSVRWAPHSLRHVDILSSDSHSLSSSHLLLAVGDRQGRLALL
DFKSRSPLLWFDSSHNQPPSLKLGIQDICWVKSSIDSWALAAITGPHMLSLYSTSTGRCF
FKYDAVSEFLSCIRRDPFDSRHFVVLGLKGFLLSVKVTADTEDDVVLQEFQIRTDSSELA
KLEKDLNGGGGGSGGGSHHGGSGSSSNNSSNTSPASAIFPNYIAKCAFSPEWQHILFVSF
PRELVVFDLHYETALFSANLPRGGRFLDVLPDPNSELLYSVHLDGKLTTWRRREGEQAYS
ICSTQELMPSVGSCVPSPSILAAVLCESDYALQNVGKIYSDVPHTPFSDEDFDNPFDFCD
ESLPASKTHLVSISDDGKVWNWLLTADGPEVVPKDVPKTKALVNDSGSRTSDANAGNDTN
EGSERFRGRERSSKLTVVPEDTSFKIILVGQLHLLSSTVTTLAVPSPSLTATLARGGNHP
AVAVPMVALGTQSGAIEIVDVSANAVTSSFSVHHGVVRGLRWLGNSRLVSFSYTQANEKS
GGYINRLVVTCVRSGFNRAFRVLQKPERAPIRALRASSSGRYLLLLFRDAPVEVWAMTKN
PIMLRSLALPFTVLEWTLPTVPRPSASTKQSSASLKDRIVGTQAGTSPQANDAPQEPKPV
SSEGSQDESSESFSFALVNGALGVFEVQGRRIKDFRPKWPSSSFVSSDGLITAMAYRLPH
VVMGDRSGNIRWWDVTTGQSSSFNTHREGIRRIKFSPVVSGDRSRGRVAVLFYDNTFAVY
DLDSPDPLANSVVQPQFPGTLVLELDWLHLRSHNDDPLVLCIAGADSSFRLVEVNVTDQR
PAHGAIREKFRPMPLCAPILLPTPHALALRMILQLGVKPSWFNTSSIMINKRPHHIPGTP
KSEADLRSYIIDTPPVGDVAVPEMLLKVLEPYRQEGSILDDERARLYAKILNKGSAVRFA
FASMIFGESSEALFWLQLPRALNHLIKKSLIKQPQKKATLEPVSQVDEVALLTEIKSSGK
LLPGSDRRESLSQGQLRLMAFEQEELWETANERILWHEKLNGEEAIQNQVHDLVSVGNLE
GAVSLLLSTSPESHYFHANALRAVALASAVSKSLLELAVKVVAANMVRTDKSLSGTHLLC
AVGRHQEACSQLQDAGCWTDAATLAATHLKGSDYSRVLQRWADHVLHTEHNLWRALILYV
AAGAFREALTALREAQQPDTAAMFVVACREIHADILANMEDAGQGVESSTKDQLLVLPEL
SLENEEVIAAYEVYGQYQRKLVHLCMDSLPFSEQ
>Sgl46785 E3_adaptor/Cullin_RING/DCX/DWD 19.9 0.4
MGQANSREGLELSDSDDYDERDSDKEEDYDTSEENQLHSTPPSSSSLDDVESRLKALKLK
YSTPAPASATASASSLRRKNAVKLYCHVGGNTSDSKWKTADASTSYSFVKSKESEDEDED
DEEDEDDEENMDGCFWQLRVGSKIRARVSSDLQLKMFPDQLRVDFVWNGVWALKFFEKNN
YYDMFLSEFQDCLFENVFGLKASDENKLKVYGKDFMGWHNPEAADDTMWDAVDEEAEVKT
PASSSRIKQDLLEEFEEEATGIQSMALGALDNSFLVGKDGIQVVKNFRHGIHGKGVTVKF
DRGSGNSSSYSTPKKAILMRGETNMMLMSPVLEDKPHAQGLHQLDIETGKVVTEWKFAKD
GADISMRDITTDNKGSQLDPSGSTFLGLDDNRLCQWDMRDRRGLVQEIASANSPVLHWTQ
GHQFSRGTNFQCFASTGDGSIVVGSLDGKIRLYSKTSMRQAKTAFPGLGSPITNVDVTYD
GKWVLGTTDTYLVLICTLFTDKDGRTKTGFGGRMGNRVSAPRLLKLTPVDAHMAGPAPNN
KFHSGQFSWVTEEGKQERHIVVTAGKFSVIWNFEQVKNSAHECYRNQQGLKSCYCYKIVL
KDESIVDSRFMHEKFAVSDSPEAPLVVATPMKVTSFSISNKQ
>Sgl46799 E3_adaptor/Cullin_RING/SCF/F-box 20 0.0
MPTLVNYSGKDELSMGLVDAYGPPFKRARITAPFVLWGHESEQEKRSSISVLPDECLFEI
FRRLPGQERSNCAGVSKHWLTLLTSIRRTEMWDKDTVVMSDDKEVDGCLTRSVEGKKATD
VRLAAIAVGTAARGGLGKLSIRASSGVTNSGLSAVARGCPSLKSLSLWNVPSIGDEGLFE
IANECHLLEKLDLCHCPSITNKGVSAIAEKCPNLTTISIESCHNLGNDSIQAIAQGCPKL
ESISIKDCPLVGDQGLASLFSSSSSVLTKAKLQSLNISDFSLAVIGHYGKSLTSLTLSSL
KNVSEKGFWVMGNAQGLKALSCLSISSCLGVTDLSLEAIGKGCSSLKQISLRNCCFMSNN
GLVGFSKSAESLETMQLEDCNRITLIGVVSALSNCSSRFRSLSLVKCMGLKDMPFQDAAL
VNPCISLRCLSIKNCPAVSSLSLSILGKMCPNLRQVDLSGLYGVTDEGVLSLLESSLAGL
VKLNLSGCIKLSDESVVAIAKLHGETIKVLNLEGCRKITDVSLSTISSSCPVLSELDVSN
SAVTDSGVAALSCSELNLQILSISGCSKISNKSLPYLIQLGKSLVGLNLQFCNSLSSSIV
DMLMGNLWRCDILC
>Sgl46884 E3_adaptor/Cullin_RING/DCX/DWD 92.2 15.6
MEKKRVAVPLVCHGHSRPVVDLFYSPVTPDGFFLISASKDSTPMLRNGETGDWIGTFEGH
KGAVWSCCLDTHALRAATASADFTAKVWDAITGDVKHSFEHKHIVRSCAFSEDTHLLLTG
GMEKVLRIYDMNRPDAPPREVDKSPGSVRTVAWLHSDQTILSSCTDIGGVRLWDVRSGEI
VRTLDTKSSVTSSEVSQDGRYITTCDGTSVKFWDANHFELVKSYEMPCTVESASLEPKYG
NKFVAGGEDMWVRVFDFHTGEETACNKGHHGPVHCVRFSPGGESYASGSEDGTIRIWQTG
PLSQEENDVAATTASSGKVRAAAAAEEVSQKMEGFHIADEGKAKEEVTNAK
>Sgl46900 E3_adaptor/Cullin_RING/DCX/DWD 81.9 11.7
MQQQKSQQQQQQMQMQQILMQRQAHQHQQQQQQQPRRDGGQLLNGSANGIANSDPLMRQN
PGSANVMAAKMYEDKLKLPLQREASEDIKPRFGDNVGHLLDPNHASMMKSAATGGQHQGQ
SLHGNAGSIPGNLQQYQNRSPQLPLSGQDVKPEINPMINARAGGPPGSEGSLIGVPGSNQ
GGNSLTLKGWPLTGFDPLRPGVLPPQKSMMQSPQPMHQLQLQQQQLLMQAQQNLASPSMD
MEARRRMILNNNRNVSLGKDGQLTSVGEVVSNVGSPVQAGCPVLPRGESDMLIKQQLPNN
QPQPQNPQNAPSGQSPQIPNQTDKTGSTSMTMDANLSNSFRGNDQASKGQMGRKRKQPNS
SSGPANSTGTANTAGPSPSSAPSTPSTHTPQDVMSMPNLQHNGGSSKPSLMFGSDSAGTM
TSGPNQLADMSRFGDEATLDDNVESFLSHEEGDPRDAMGRGMEVSKGFTFKEMGLIHASA
GKVNCCAFSSDGKLIATGGHDKKVVLWHTDNQSLKASLEEHTHMITDVRFSPSLSRLATS
SFDRTVRVWDADNTGYSLRNFTGHSTSVMSLDFHPTKEDLICSNDSNGEIRIWSITNGSC
PKVSEGGTVQVRFQPRTGKYLAAASELGINIIDVEPFRLVQQLQGHAQKFHSVCWDSNGE
NLACVSEDMIRVYNVGAGGKFQRVHELPCTGNKFNTCVFHPVYPSLLIIGCYQNLELWNM
MESKTMTLVAHEGQITSLATSTLTGLVASASHDSYVKLWK
>Sgl46909 E3_activity/RING/RING 34.4 8.6
MAVSSEEPTRESADHYPLLMEGCNSHRNDGHVIDIERGGEASSSNSPDLEYSRGVSPHNG
PREINDMQAPHNEPPSPSPSRTVSRSSSFVRRSEGIGRRNWSPFNSGFWISVELVFTLSQ
IIASLTVLCLSRHEHPQAPLFAWVVGYTTGCFASLPVLYWRFLHRNQGAERGALQANQAS
PRANSPSDPNSYVTISLSQSSEHENHQSAPESTFEGQSMEMAMTRVGLLMDHFKMALDCF
FAVWFVVGNVWIFGGHASATEAPNLYRLCIVYLTLSCIGYAMPFILCAMICCCLPCIISV
LGIREDLNQVRGASEECINALPTYRFKAKKDEGGSTGQTEYETEGGVVAVGTEKERAISG
EDAVCCICLASYIDDDELRELPCTHFFHTECVDKWLKINATCPLCKYEVVERDDTLSSPT
NAAPQS
>Sgl46964 E3_activity/RING/RING 28.2 2.7
MELKAVKDAFDPVTKKQKLCSSKFNEVVEQLGQKIEQALLNLHSADASSSYPDQKAIVTD
LKTNLKDIAHATQLESSQKEVNGALSKYPKQLEKHFNPDISKAYRNVDFDNHLINQIIIS
HLYREGLFEVGDCFADEAGEKEATALKSPFIEMYHIHQAIKSHNLEPALQWASANCDKLR
QNGSDLELKLHRLQFVEVLQNQGRDDALKYARTFLAPFATSHLAEIQKLMGCLLWVGKLS
ISPYPDVLAPINWEKLGDEFTRQFCNLLGQSFESPLSVTVAAGVQGLPTLLKLMNVMMSK
KQEWQTMKQLPVPIELDKEFQFHTIFVCPVSRDQATEENPPMLMSCGHVLCKQSITKLSK
NSTKTFKCPYCPSEIEASHCKQLYF
>Sgl47032 UBD/Alpha-Helix/UBA 17.5 0.0
MTPVIPCSVSNISFIPGTSFITRKSRCLTRYNRSVNPTIQSVSSKKHFIALPQSLTVFQH
LKTVSSRIQRLSATGTDVAVEEQGSDVADEASSTPPDQVTNEQPTTKSDSSSAPTRAKRR
LGRKSEMPPVKDEDLVPGTVYTGKVRSIQPFGAFVDFGAFTDGLVHVSKLSDTFVKDVND
VVSIGQEVKVRLVEVDNDTGRISLSMREDDSNNKPQQNKDGSNDKPRSARRNANLNSQKR
RSEVKKTSKFVLGQDLAGTVKNMARSGAFISLPEGEEGFLPRSEEPDDGFGNVMGETSLE
VGQEVNVRVLRTTRGTVTLTMRKDEDVKKLDSKLNQGVIHTATNPFVVAFRKNKDIAAFL
DEREGVEEPAETPASIEVESSTENVAETTTEEPDSEVIATSQDIPDEEDVATTTKEEAEE
PNSEVVATSQDDIPDEEDAATTTKEEVEEPNSEVVATSQDIPVKEDETTPVSASPLTEEK
EKTSEASSITQEVVAETQVESISAKEDQPVEIPTDEAKMETLSPEDNQSIDASSAEDEAT
ATLSPAPLAEDGDTKTEESPVNQETVAETQAETVSAIEDVPVEIPTSAASVETASPEVNE
SINGSSGGPNGSSPLENVSKAAISPALVKQLRDETGAGMMDCKKALSETGGDIVKAQEFL
RKKGLASADKKASRTTAEGRIGSYIHDSRIGVLVEVNCETDFVSRGDIFRELVEDLAMQV
AACPQVEYLTTDDVPKDLVDKETEIEMQKEDLLSKPEQIRSKIVEGRVNKRLAELSLLEQ
PYIKDDKVVVKDWVKQTIATIGENIKVNRFVKFNLGEGLEKKSQDFAAEVAAQTAVKSAP
ATAEEPAQPAAAEPEKAVEKPPTVAVSAALVKQLREETGAGMMDCKKALAETGGDLEKAQ
EYLRMKGLSSAEKKSSRLAAEGRIGSYIHDGRIGVLIEVNCETDFVGRSEKFKELADDMA
MQVAACPQVQYVSIEEIPESIVSKEKEIEMQREDILSKPENIREKIVEGRISKRLGELAL
LEQSFIKDDSVLVKDLVKQTVASLGENIKIRRFVRFVLGEQAESSNTETEE
>Sgl47047 E3_activity/RING/RING 30 6.8
MITRVNHLFLIIFIIISIKLASAQEDDHEQQHTPTSSNFQPSLFVVIGVLSFMFSLTSIL
LIYARFFYRQPSAIHSISRNQETNNAAVFGNDTRFSGIDKKVVDSLPFFKFSSLKGAKQG
LQCAVCLAEFEDVEVLRLLPKCKHGFHIECVDLWLEHHSTCPLCRQTVSAEDLTTFNTSS
SMRFITNGGGERQKSDVGEDAAAVGTAAASSASVELFLDRENNSVERCSRFSSFRRVFST
KVEDEVVQIQVDEKVLNRLNHQIVVSDVVFKHRWSDVSSSDLMFLNSEMLGVMSSDRVTC
SSNNNSNDDDADAEYRIINIRDEIERKKNFEDRVEQIKGCNSKEGFEELNGTNMNSNHTR
RNSLILPGDKRSMSEITALSRFKEMMSMKNKLRQCLTDNNSDNCNINDDDLIKRRKKWFP
IAKKTVQWFANREKNKSQQPQQSQGTSQTSDQSIDKSVP
>Sgl47073 E3_activity/RING/RING 26.9 13.8
MAAMSFSNYSVDLQFDLDEALDCSSTTMIIKPPSSTSSSPPSSSSHNYVINDDDNNIISD
DNNNNNSSSSLISRVYMELPTVAVGNDSVCCVCMEGFLQSHDHLHQINGAKQLPCRHVYH
PDCILTWLSSSHHSCPLCRHIIFHHDDDDDHQTFKSS
>Sgl47074 E3_activity/RING/RING 35.1 4.6
MATFSFDGVFDLDDALTMPMISTPIISPLTIVNVAETLLTFPTVATPNDAVCSVCTENFV
PPRGGGRRIPCGHVYHDDCIATWLSVRDSCPLCRVVVNQSSQIKKTSC
>Sgl47075 E3_activity/RING/RING 40.9 7.6
MNSNILYSYPINIHQTFDLDEALTMPPSPILNISHNVPPDHSSCATLPTVTVENNVICSV
CMETFRQSAKRMPCGHVFHATCIAPWLSINNSCPLCRNIVFGNAS
>Sgl47098 E3_adaptor/Cullin_RING/DCX/DWD 48.2 9.0
MGNKIARTTQASATEYYLHDLPSSYNLVLKEVLGRGRFFKSIQCKHDEGLVLVKVYFKRG
DQIDLRDYEKRLFQIREIFRSIENPHVWPFQFWQETDKAAYLLRQFFFNNLHDRLSTRPF
LSLVEKKWLAFQILVAAKQSHEHGICHGDIKCENVLVTSWNWVYLVDFASFKPTYIPDDD
PSDFSFFFDTGGRRLCYLAPERFYEHGDDMPVAPDAPLKPSMDIFAIGCVIAELFLEGHP
LFELSQLLAYRRGQYDPSQHLEKIPDPGVRKMILHMIQLNPDARLSADGYLQSYAGLVFP
NYFSPFLHNFYSCLRSLDSDARVVMCQSAFHEIVKQMTDNKFSIETSGGIRNSPGKTSQQ
TVSQQVQCHPKVALKKDLLTRGLANERFELFGDLNALLRDVDHSNHFSTDKTNKDDLSKI
NILQSQEVYRLQIPDLLQSISDVFKRREHAFLKTITIDDLKSLMSEYDDESDTYRMPFLQ
LPSEDMSCEGMVLITSLLCSCIRNVKFPQLRRSCILLLKYSSIYIDDEDRLQRVVPYVIA
LLSDTSAIVRCAALETLCDILPLVREFPPSDAKIFPEYIFPMLSSLPDDPEESVRICYAS
NISKLALTSYGFLVHSIRLSEAGMLDELNAPQKSTPSTDNGQALKVYSNAQLAHLRKSIS
EVVQELVMGPKQTPNIRRALLLDIAGLCCFFGQRQSNDFLLPILPAFLNDRDEQLRTVFY
GQIVYVCFFVGQRSVEEYLSPYIEQALSDTTEGVIANTLDCLTVLCYSGFLRKRVLLEMI
QHAFPLLCYPSQWVRRSVASFIAASSESLGAVDSYVFLAPVVRPFLRRQPASLASEKAVL
SCLKPPVSRQVFYQFLENARGSDMLERQRKIWYNTSAQTNQWGTVDFPRQDDELLSLENW
PDTNGNLENDNAVGFPADQIDSTECDSTEAKLKALRGYIHNSSSTIDIRDHISSDKLQFS
GLITPQLNSMNSLLHEKSSENIPLYSFSLDRRALGNPQAASDTSLQPNMVGLGSSTTPWM
DPVNKPFGMASSVPAPRAVSGSFSLANGSKQFHRVVHEPESRESDPTSYVSSKLQDLGIS
SNSSTRGGSMSMEDVPSSSDMAGSPSVSWTSALPDSGWKPRGVLVAHLQEHRSAVNDIAV
STDHSFFVTASDDSTARVWDSRKLEKDISFRSKLTYPLEGSRALCTTMIRGSAQVIVGAC
DGKLHMFSVDYISRGLGNVIEKYSGVADVKKKEVGEGAILSVVNYSAETSSSHLVMYTTQ
NYGIHLWDTRANADSWMLKSLPEEGYISTLVTDPCGNWFISGSSRGVLTLWDLRFRIPVN
SWEYSRPCPIENMCLYVPLPHTPFSAMGRPLVYVAAGCNEVSLWNAETGSCHQVFRVPGN
DGDSEFSELPWALARPQNKANPKSDPRRNVNLKYRVDELNEPPPRLSGMRSLLPLPGGDL
LTAGTDMKIRRWDHSRPERSYCVCGPTVKGLGHDELYESKSSFGVQVVQEMKKRPATTKL
TTKAVLAAAATDPAGCHRDSILSLASVKLNQRLLLSSSRDGAIKVWK
>Sgl47171 E3_adaptor/Cullin_RING/SCF/F-box 13.7 0.0
MMEWDSSSSDDSGVDEEEGFLLNDGGSMPFPIQNLLEAAPCGFVVTDALEADHPIIYVNT
VFEMVSGYRAEEVIGRNCRFLQCRGPFAKRRHPLVESAVVADIRRCLEDGVEFQGELLNF
RKDGSPLMNRLRLVPIYGDDEIITHFIGIQLFSEANVDLGPLPSYTAKESLRSSDLFRSS
LSSFQPFQSRERNVCYEVCGLLRLSDEVVALKILARLTPRDIAAVGSVCRRLYELTKNED
LWRMVCQNAWGTETTRVLEAVPGAKRLGWGRLARELTTLEAAAWRKVTVGGVVEPSRCNF
SACAVGNRVVLFGGEGVNMQPMNDTFVLDLNASNPEWRHVKVSSPPPGRWGHTLSCVNDS
NLVVFGGCGTQGLLNDVFVLDLDAKQPTWREISGLAPPLPRSWHSSCTLDGTKLIVSGGC
ADSGVLLSDTFLLDLSLDKPVWHEIPAAWSPPCRLGHTLSVYGGRKILMFGGLAKSGPLR
FRSNDVYTMDLNEDEPCWRSVTGSGMPGAGNPGGTAPPPRLDHVAVSLPGGRILVFGGSV
AGLHSASQLYLLDPTEEKPTWRVLNVPGWPPRFAWGHSTCVVGGTRAIVLGGQTGEDWML
TELHELSLASSVIHEDQL
>Sgl47228 E3_activity/RING/RING 34.3 8.6
MPRNNRNRQNAVVGDNFNPPISDDIRQLNSPEIPTKSNPKFLSLVLQALIMAFVISLFFI
FIGVAAIIFLHLCIAGGALRHRRNRRRPDSGNLDSSSGYSLELLETLPKSRFKGCEVCAI
CLDNVLEGEICRVLPNCKHVFHLNCVDKWIVKSPVCPVCRSSVKSVDHHEGKGRGAFDWE
HLWSACG
>Sgl47239 E3_activity/RING/RING 30.2 10.4
MERNPLAPLAEQHHNNVDSSGLNLDNKISPSIILIIIILAIIFFVSGLLHLLVRFLLKPN
ERNPDEFSDNVTALQGQLQQLFHLHDAGVDQSYIDTLPIFQYKTIIGLKDPFDCAVCLCE
FEFDDKLRLLPKCSHAFHMDCIDTWLLSHSTCPLCRASLLQDFGTHNHGLGPGLGFGYGL
SPVVCVLESGANTVESSMELERDPTHSGPGIGPGLIQQQQREGEFGSNRSDIGRKSSGSV
QEIGKSEDSNNKIVTVKLGKFRSVEGGEGSSDINYFSNNNNVSGNSNGNGNRNGGGVSSN
ELGSRRCYSMGSFAYVLDETTSLQVPIRTPMKKEKNAAKKGNLKIGHRVAMSEYGGGGDS
MREFNGIEFQGKGNESSSKKESFSISKIWSRGGGDKKGKGNGNGIGIEVDQSSRRTISEF
EIDVSELGNDEETQSCYSVDSLANNPNTTTSSSSTRRTLLWLMGRQNKIVHNHSSFSSNV
>Sgl47240 E3_activity/RING/RING 12.3 13.2
MRFLSIVGNSLGCSASGERLVSAARDGDLLEAKALLEYNPRLVRYSTFGVRNSPLHYSAA
QGHHEIVTLLLETGVDINLRNYRGQTALMQACQHGHWEVVQTLILFKANIHRADYLNGGT
ALHLSALNGHTRCIRLLLADYIPSVPNTWNLLQNKSKKDYGISEFNASALHQVINKPADG
GITALHMASLNGHFDTVQLLLDLGASVSEITVEDGTTIDLIGAGSTPLHYAACGGNLQCC
LVLVARGASLVADNANGWTPLMVARSWHRDSVLEILSTPQDIPLSTLPSPYLSLPLMSII
KIARDYGWRSSEFVPACQDPCVVCLEGRCTVASEGCNHEFCTRCALYLCTINCASAVAKG
PPGSIPCPLCRHGIVSFVKLPGTRPIPKEIARTSLSLSFCGCSCEKNERTPLTMPLCRPP
PVSSSSSSIRVSPLSSSFRSLSCQRFPSMKLNSGCCIGGSETSPSIISGSVNRSLKNQLS
RCGRVRLRRSSSHTEGRKSWFCSLNQYVATNS
>Sgl47267 E3_activity/RING/RING 30.6 3.7
MPRNNRNRQNAVVGDNFNPSISDDIRQLNSPEIPTKSNPKFLSLVLQALIMAFVISLFFI
FIGVAAIIFLHLCIAGGALRHRRNRRRPDSGNLDSSSEGEICRVLPNCKHVFHLNCVDKW
IVKSPVCPVCRSSVKSVDHHEGKGRGAFDWEHLWSACG
>Sgl47269 E3_activity/RING/RING 34.3 8.6
MPRNNRNRQNAVVGDNFNPPISDDIRQLNSPEIPTKSNPKFLSLVLQALIMAFVISLFFI
FIGVAAIIFLHLCIAGGALRHRRNRRRPDSGNLDSSSGYSLELLETLPKSRFKGCEVCAI
CLDNVLEGEICRVLPNCKHVFHLNCVDKWIVKSPVCPVCRSSVKSVDHHEGKGRGAFDWE
HLWSACG
>Sgl47313 E3_adaptor/Cullin_RING/DCX/DWD 13.5 8.7
MAILHPQTQQQNNFQVHHLPQSNYIDAVRWLAPISAFDKFVIFSLFDSNSSSSTIELHSL
EFTDSSNPKPILSPLSSSSPSLSRTSSLKTSQSLIAFSTFSGSLNFLSPNHTSSGEISLN
STLSLQEKGFHVGPISCIDVLESECVSVGEDGRVNLVGFSGGKPSYRRVFDSNGLVCYTA
VKWASPSEFATGGLGCSLQWWDQRRKPGEPALHFKPQKSASGVVHSIDIHPSRKHTCMAG
GSSGTVFAWDLRWPQQPIVLSGVGISEKPSHPVSESEVWEVQFDCHSQSSNIASMSSSML
PAMMCSEDGILAVLEPGSEPVELLEEPCAINSFDIDKQNYDVICSLEWESVAILTRS
>Sgl47316 E3_activity/RING/RING 24.6 3.6
MSNKGDKETGREGHVQGDALIIESISSNNASMGVTTRRRSMIKSKKSEASSVAAKNPIKV
GVSENEPRNSGAKTASTSGSIQIASTEVPLTTKRRSAVKRAVPSEAQNKETGGSRLETDQ
VAQGSSVGKQPDSPVRKSKAKTATSQQAWKEKAQPESSTKKVSPRKQQGQASGSTSKPPT
NTTNASKQNKSANQKQGSSKKAVPKDQTPHGKQAKHKPSTSASQLNPSDYPKYHIEWKGF
QEPHRLEVSCCLCENDIRVAPMETNLDSGFYEFSAIPVVAILPCGHVYHNDCLSRGELEQ
QQTDPICVFCDSL
>Sgl47400 E3_adaptor/Cullin_RING/SCF/F-box 13.1 0.0
MNTEDNRTELQGNSDWAELTHECLLNILSRLPLEDRFKGAMLVCKPWLEACKDSSLNTIL
DLEPYFESLTESTRWWSPEFERKIDSILLFVADSCNGRLTKICVRHCSDLALMFAAQRCP
ELEVLSIKSSQSVSDAAMAEVAKRCPKLKELDISFCHEISHESLSLIGRSCPNLKVLKRN
FMNWLDASQHRGIVPNEYLNACPQDSDSEAAAIGKCMPNLKHLELKFSKLSGKGLALISE
GCLNLEYMDLNGCANLTSRDILNASTNLKRLETIKKPNFYIPRSVYHTERTYSQNPNTPE
THHKTNPFTIWPRRSLWSRLSMVDYHARIDLPCKFHNPQCS
>Sgl47423 E3_activity/RING/RING 11.7 5.5
MTLEILFDCAKVRKKLTSDDLYEINTPTHDYGQFIDLYRSIAKHPTRETSQIPHLPTEEE
MSRVDFPRVDWDTDPTAEDLEESNSMRKKRGQKAPKRGVGGRVSGSSRGTKKKRTFRPCF
LVSMKVRQASVLLLYKRENVYCAGARDMFGNWWDFSINGGVLFPGSRGLGFEESYTKMEL
LNKRATVGLQQLEHAVFVFSNPAAHSVDDRKIAAQILIAVTSEAGRFKILERLFDDALND
DTGLSNVDVDGDYRVLMRNWETVSSHIFKEYAKDTGIGEKISNNKLVELLEGAGMFNFNN
PEKFLGLLIRNLGSKTHSNLKRELQREWEMRKRQRRLEVASKKYDVAMFQLGVDQFPENQ
STMKRDEILHDDFAAASSFSTSNSAHSVCKKKDDGNALTENDFNNSGNMPDSNYREQNEK
VQPLKEEFSPLPAYGQSILVSLTTRCVWKGVVCERAHLFRIKYYRNFDKPLGRFLLDDLF
DQSYRCRVCEMPSEAHIHCYTHQQGILTISVRKLTEFPLPGERECKIWMWHRCLRCPRVN
GFPPATRRIAMSDAAWGLSFGKFLELSFSNHAAASRVASCGHSLHKDCLRFYGCGRMVAC
FRYAPIVVHSVYLPPSKLEFSCANLEWIQREANEVNDEANRLYTEVRNLLNGKFLSSKSM
ENNSRACGLKKHILELERILEKEKEELEESLQKVLQMEGWN
>Sgl47447 E3_adaptor/Cullin_RING/SCF/F-box 14.3 0.0
MFRRPFRRWDPHEIYNAHCHSYFLRLRSSNFRFTNLMILRDENYMKHVEEFNNIVSSRRT
LFVTKEKDISNYQAGPAVPKAIDVQTKEVQPVLMEVTINTELDDRCKAVGAVEQGANTSL
SMEPSKGEQSLHSFVFTAGGQVKNSKGKGWRRRERMEGDGGMEVDADGGRVMVGNKRSVE
CDVDSVAGGEDARKRIRSSSEAQTLPTSPTEVVRRLKRWATAAAPDLIFVSETMISKAAV
EGLKERLGFSSCFRVSSFGKAGGLGIFWKSERVDFTILNFSNNHICGEVVVGEKRWCFVG
LYGWPGVSDKSRTWELLRSLTRGTTLPILVGGDFNEILSMEEKEGGSTQVRREIDFFREA
LDDCELRDLGFVGQWWTWERGKTIEKRVRERLDCFVASPQWCSLYPRAHVEHLLRFNSDH
APIILRTINGRRKKKKKGKHFKFETAWLLDDSCEEVVREAWRDGGCESVDHRLVGVGSRL
MAWSRDKFNDLGTKIEDLEKALREAQKKPISQESCDEFQFLSPTNSPMETNNSRNQNPNT
IKNLEELIFHEVFPKLPAESLLRFKFVARHWDAFIKSVEFLKTHVRHLPSHLNSNSSRSS
VLILDSRRFFQFLDYGEANFDDSSCKCLSFLISPCVDEEGIDRKIFCRRHVIGSYDILLS
SCNGIAFMVSPSEDADLSCRFGFHYVLYNPLLGPHPLVKIPHPDDNRLGSEDPWPFDSYG
FGFGYVSSTEDYYIVAINLPRGLKIVVSLYSLRSKTWRNDAIALSLSPEKVGSILPLVFK
NKYWYRNTGTLVKETLHWGIQQGLGHHIIFAYNLATLRYSRILYPAKFIATQDNVREMGL
CCLDDCLCAWAQNRRNTVELWRRKGSNWSGLFRIKTVHRVCDFFGFNKTDHFLIFSDVNQ
ANNKAGVDYKLYLSNFMGNKRLIGRHIRQKIWNAVNYVPSLESFQAMNSETNQ
>Sgl47448 E3_activity/RING/RING 9.8 34.3
MKARSSSMVDDDTLPQINQFFKTLKSEKPPISPKFKQKRMSNHHQKRSVSDLIILERGDY
SSEIKHNVVIDLNDDDYGGNSVKIIDDNDDDDDCVFVKSEVNLTNNIGNDKKYPICIENC
EKEMKSNGKSKLRKNFTIDLDDSVQCVDDYDDNDDVRVINVKSSSRKRRNTFSVFEIGES
SGSKREEETDEVVTVVEPVEVMFLCEICADSKPRKEAFKIKGCSHSYCSDCMKTYVASKL
QDGVSVINCPVPSCSGVLEPEYCREILPFEVFTRWGNLLCESVILASQKFYCPFKDCSAL
LVDDGGEKVTSCECPSCYRLFCAQCKVAWHAGIGCAEYQSLSKDERNSEDIMLRKLAKSK
KWQRCPKCKFYVEKSEGCLYMKCRCGIAFCYHCASVFKNPNYHYCNKCRR
>Sgl47456 E3_activity/RING/RING 24.3 13.0
MGKQKGESARNKARASSSSLAASLVPAGAAPIGFGGYVGSSRVDSAFRGDESTSFAGIDG
DMVLHLKRLARKDPITKLKALNSLSTQLKDKSGKNVLPIIPQWGFEYRRLLMDYNREVRR
ATHDTMTSLVSAAGRDLALHLKSLMGPWWFAQFDSVPEVSQAAQRSLQAAFPSQEKRLDA
LIFCASDIFEYLEENLKLTQKGMADLASASDELAEMHQRAISSSLLALATLLDVLIGTKS
EKSPGEDLKNQSKKVSKVQDMAISSAKSLFLSHQYFLDFLKSESPVIRSATYAVLRSFIK
NISEVFSEENVKGLSTAILGAFQEKDPSCHTALWELFLLFCRRFPGSWSYINFHKTFSNR
LLQFLRNGCFGSQQVSYPALVLLLDTLPPEGIGGLKFFVDFFQCLWAGKNASHPSMPDRM
AFFVALKECFLWVVHNSGRYCSGEDAIHNFRISLVENILVKNLWHDFLFHSEAKHEDIST
SSNNEDTFSETSKVLVKDRSEIKQGQLHDLGRCIIDVLCAMHSLECKLLAPFCDAFQDCC
LETFQQAESVKVPSGKTERAVKFLLLVQKYTNLNSESWPLSYLVGPMLERSLPLIISLDS
PEAVNFLSTVVSIFGPRKIIPRFIQSEGIADDSATDLAEKELSKFLKVFENTFVSWCFSG
SESSLNARMDLLLALLDDQCFNKQWDVIISYAANMHHSTASCIGRLATFIEKARKLAMKK
SLLDGNEMFEIACWRHELLDFLAISIMQSTSHFTDSDLQFIRAVLGGTSEDDAISFLSKT
SVIQIYTEMFGKLIAFVMESPISCVRNFGSLLCTLLKSTTSEIQESANVARMAYISLEVL
KSTPFSLKSYCEGSDLLPAIGGIVFVIDWEYHISRESDAKFNQTPVGSIIPRQDFGKTMH
AFRTSMDIQYWRSLLPQSRVTLRSLLIQFIRSSIFGQDGFVADMITTLCCKWIVEVGKHL
CLNLLEEQKLMDMLLSVDESWPLWITPDASNSWRNFSVKAERVLTDVNISQSQLFVALVD
KLISEMGINRVIAGSHLQVLIAEERASNEPIASQSEFSRAWVVAEMLCSWKWYSGSALST
LLPSLSSYAKKESVDDLICLFDPIVNVLLEGALICGTKSQLSIFNTWPPSNKDLDDIDEP
FLRALVSLLFTLLNEGMWNQEKAMGLWELLLNKLFIGQETDMNCLRILPPLVSVLAHFLC
HNGSNDLVKDFRETVVRDWLEKTLTFPSLISWTSGEGMKEWFQLALSCYPLSTTADMGHL
KLDPSSSEKKLILDVFRKQRHDGNSLIVTNELPVVSLLLSRLIVIAVGYCWKDFHEEDWT
FVLAHMRSWIELVVSTLEEAAECLDLEIGNGSGDNLDLVINKLNHIMLNLDPSLVNVATN
AFNAFSLVMELVGCDPSDNTEKLPVLKTEACQHTIDLIQEGVLRIFFSVGVAEAISGPMS
CESLSIIARGQHAYPHFWNLVSSITVKTSTLSREQAFKAVELWGLRTGAISSLMAILFSS
KPVSDWQLASFVLLSSQPFSNWALMEDHVSDSLTESSTVDIGSHGIDLSSENNFPLREEI
HILIHKLPLEILDMDLESQERVHVYFAWCLVLCYLSSSSNREKLVQYIQESASSAILDCL
FQHIPFELGASLVSKKKELETPPELLNIAAAATRAVSTGSILFAIESLWPIGPDKMASLA
AATYGLMLRVLPAYVRVWFNDLRDRSASTAIESFTKTWCSPHLMADELSQIKKSDFVDEC
FSVSVSKSANEVVATYTKDETSMDLVIRLPASYPLRPVDVECVKSLGISEVKQRQWLLSM
MSFVRNQNGALAEAIRIWKSNFDKEFEGVEECPICYSVIHTANHSLPRLACKTCKHKFHA
ACLYKWFSTSHKSTCPLCQSPF
>Sgl47546 E3_activity/RING/RING 36.1 8.1
MAAIDTTLTLGEGSNAAGPSSSASKKPKRFEIKKWNAVSLWAWDIVVDNCAICRNHIMDL
CIECQANQASATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNSEWEFQKYGH
>Sgl47606 E3_activity/RING/PHD 42.2 25.2
MAEFSNQGHQLNYTNNFLFNDKVEVRSLEDGFQGSWHAGVVIACDSRYVKVKYKHLLLDD
ESDHLTETVEVDSTEGVLSSSKSRNRGRIRPIPLMGKVSKLDLHYGLCVDCYYKDAWWEG
VVFDQDNGSSKRNIFFPELGDEMTCGIKCLRLTQDWDEVTGDWNPRGRWWFMVMFEEFEK
NNYIPVSLKQIWYDTRERKEFGEIGEWPSPLWHELIEQVINENVQLTVNEFLTRYLSSEA
TSALDATLNHHPIPVNYVSAVPSAMDVILQGVDFTREIEGDLAMVGELVENAALAVDLLE
SSPTSMKIVPVQPMALSAICSDQEGLDSDTIYESEFTTNSRSNENKQLRRNKRKLEPDES
RINDLKPDCCPQSMYDYIQRDRPGSTLTTKVRCHLLYLGYKMEHASTRKYVQYTSPEGKK
FCALRACLNFELAKEEISPQAAEDVQTGKVSSAFNLNCTSPVRVASTSKVCDKKSQAKLL
DLDIEPKFCPEAVHKYVRSSEKRYPCRSELQDEVRSHLLAVGWNFWGKVKQGREEWRYDS
PTTNKTYYSLMSVCKAITNGVEILGSSPSEDANNENLKEHSGGELLLSNKEVSGNPLSQK
RSRKFPRAFRKCKASKLQRRKPDGFEHSMPSLLGIGEKEQEVGNNGSAKRHCHSMTTSFL
SKKNKVLGKVKNCSDSSNLSQVPRSSKRLRQAGPSISSQAPRTVLSWLISNGVVLGREKV
YYYRQDANRPSAEGRVTCSGINCSCCGRDFTISGFEAHAGSYSLWPAANILFDRDGKSLV
HRQLELVRQKIRISRGPLEKSKGNGQDNWNDHICSVCRYGGELILCDRCPSSFHASCLGL
QEIPEGEWFCPSCCCGICGDSYSDMNTECSSDQRILTCYQCERLYHACCIEKTDMIKLDV
PPTENWFCSKMCEKVHWGLQQLLGKRIVARHNDLTWTLLKPMDYGDIHRDDCDLSSLTEN
YSKLSIALEVMHECFEPVKEPESRRDLVEDVIFCRGSKLNRLNFRGFYTVLLERNDELIS
VAILRVHGGKVAEIPLIGTRVKYRQLGMCRLVLQEIEENLIKLGVKKLVLPAAPSVLKTW
TTAFGFVQVTESERSEFLSYSFLDFQDTVLCQKVLRKLPAPLPQLTRVMPRAHYQDHRIV
EGRSIIADPEGNSVSTEVSEGSEIVDHGTLASGLEDKLNSNGGDGGGGDGQDMPIVMITD
PTNRECESSTFLDLIEQKIERDKCGGFEKFYERKKAVELRSSAPKSNCPNLEVSCR
>Sgl47611 E3_activity/RING/RING 33.6 10.0
MSNSPNYHDFGPPSLNDQSNNNNQYNLSMLYFGFLVVATAGLILAIYHCIVFNFCTDYPS
SLLLRHSTSSSGGGGSGSTPSHHGFNASKLKVVELESVLFKYNKKEKGVQLQTEQEEEEE
EEECVVCLSVFEEGEDVRKLVKCKHCFHAPCIDMWLYSHFDCPLCRATLGDAAAAAAAAA
TGVSVPPSEGNSGARYSDSGVLPV
>Sgl47627 E3_activity/RING/PHD 40.9 25.3
MAEFSNQGHQLNYTNNFLFNDKVEVRSLEDGFQGSWHAGVVIACDSRYVKVKYKHLLLDD
ESDHLTETVEVDSTEGVLSSSKSRNRGRIRPIPLMGKVSKLDLHYGLCVDCYYKDAWWEG
VVFDQDNGSSKRNIFFPELGDEMTCGIKCLRLTQDWDEVTGDWNPRGRWWFMVMFEEFEK
NNYIPVSLKQIWYDTRERKEFGEIGEWPSPLWHELIEQVINENVQLTVNEFLTRYLSSEA
TSALDATLNHHPIPVNYVSAVPSAMDVILQGVDFTREIEGDLAMVGELVENAALAVDLLE
SSPTSMKIVPVQPMALSAICSDQEGLDSDTIYESEFTTNSRSNENKQLRRNKRKLEPDES
RINDLKPDCCPQSMYDYIQRDRPGSTLTTKVRCHLLYLGYKMEHASTRKYVQYTSPEGKK
FCALRACLNFELAKEEISPQAAEDVQTGKVSSAFNLNCTSPVRVASTSKVCDKKSQAKLL
DLDIEPKFCPEAVHKYVRSSEKRYPCRSELQDEVRSHLLAVGWNFWGKVKQGREEWRYDS
PTTNKTYYSLMSVCKAITNGVEILGSSPSEDANNENLKEHSGGELLLSNKEVSGNPLSQK
RSRKFPRAFRKCKASKLQRRKPDGFEHSMPSLLGIGEKEQEVGNNGSAKRHCHSMTTSFL
SKKNKVLGKVKNCSDSSNLSQVPRSSKRVRQAGPSISSQAPRTVLSWLISNGVVLGREKV
YYYRQDANRPSAEGRVTCSGINCSCCGRDFTISGFEAHAGSYSLWPAANILFDRDGKSLV
HRQLELVRQKIRISRGPLEKSKGNGQDNWNDHICSVCRYGGELILCDRCPSSFHASCLGL
QEIPEGEWFCPSCCCGICGDSYSDMNTECSSDQRILSCYQCERLYHACCIEKTDMIKLDV
PPTENWFCSKMCEKVHWGLQQLLGKRIVARHNDLTWTLLKPMDYGDIHRDDCDLSSLTEN
YSKLSIALEVMHECFEPVKEPESRRDLVEDVIFCRGSKLNRLNFRGFYTVLLERNDELIS
VAILRVHGGKVAEIPLIGTRVKYRQLGMCRLVLQEIEENLIKLGVKKLVLPAAPSVLKTW
TTAFGFVQVTESERSEFLSYSFLDFQDTVLCQKVLRKLPAPLPQLTRVMPRAHYQDHRIV
EGRSIIADPEGNSVSTEVSEGSEIVDHGTLASGLEDKLNSNGGDGGGGDGQDMPIVMITD
PTNRECESSTFLDLIEQKIERDKCGGFEKFYERKKAVELRSSAPKSNCPNLEISAIMATQ
MSKKRKFVADGVFYAELNEVFTRELAEDGYSGVEVRVTPMRTEIIIRATRTQNVLGEKGR
RIRELTSIVQKRFKFPENTVELYAEKVNNRGLCAIAQCESLRYKLLGGLAVRRACYGVLR
FVMESGAKGCEVIVSGKLRAQRAKSMKFKDGYMISSGHPVNEYIDSAIRHVLLRQGVLGI
KVKIMLDWDPKGKVGPQKPIPDVVIIHPPKDDDIYARVPVLTQEVELVDPVVA
>Sgl47636 E3_activity/RING/RING 33.7 10.0
MSNSPNYHDFGPPSLNDQSNNNNQYNLSMLYFGFLVVATAGLILAIYHCIVFNFCTDYPS
SLLLRHSTSSSGGGGSGSTPSHHGFNASKLKVVELESVLFKYNKKEKGVQLQTEQEEEEE
EEECVVCLSVFEEGEDVRKLVKCKHCFHAPCIDMWLYSHFDCPLCRATLGDAAAAAAATG
VSVPPSEGNSGARYSDSGVLPV
>Sgl47646 E3_activity/RING/PHD 34.8 9.7
MDGGGGAQYNPRTVEEVFRDFKGRRAGMIKALTTDVEEFYQQCDPEKENLCLYGYPNEQW
EVNLPAEEVPPELPEPALGINFARDGMQSKDWLSLVAVHSDAWLLSVAFYFGARFGFDKN
DRKRLFNMMNDLPTIFEVVSGNAKKTSNSREKTTISNHSSTKSKSNSKSAKYSSKAAPAV
KDEEDGLDEELEDEHGDTLCGACGENYAADEFWICCDICEKWFHGKCVKITPARAEHIKQ
YKCPSCSNKRARP
>Sgl47648 E3_activity/RING/RING 28.7 13.3
MMGALSTLTSSQLTSLSLSLSTTFHRHHRHLISLLSSPTLFTHTLNHLYSISLPQKSLLI
ARHLLSFLRLLTPYLSPPSSTTLFTSSSNKVRLRDLDSVLLLLFFCEVRQHHPTLLEKTE
SPTHWQEILKHYGSDTMLNNMSAGFAVSLTMSPFQVLGAFVDLVVKCRKFVGSKGCSSNT
EAKREVAASVEAVVALPSVTIELGGGGVECVICKEEMKEGRDVCELPCEHKFHWKCVLPW
VSKRNTCPCCRFLLPTDDVYGEIQRLWDAIFKLNTQHVSLGS
>Sgl47668 E3_activity/RING/PHD 34.8 9.9
MDGGGGAQYNPRTVEEVFRDFKGRRAGMIKALTTDVEEFYQQCDPEKENLCLYGYPNEQW
EVNLPAEEVPPELPEPALGINFARDGMQSKDWLSLVAVHSDAWLLSVAFYFGARFGFDKN
DRKRLFNMINDLPTIFEVVSGNAKKTSNSREKTTISNHSSTKSKSNSKSAKYSSKAAPAV
KDEEDGLDEELEDEHGDTLCGACGENYASDEFWICCDICEKWFHGKCVKITPARAEHIKQ
YKCPSCSNKRARP
>Sgl47671 E3_activity/RING/RING 28.7 13.3
MMGALSTLTSSQLTSLSLSLSTTFHRHHRHLISLLSSPTLFTHTLNHLYSISLPQKSLLI
ARHLLSFLRLLTPYLSPPSSTTLFTSSSNKVRLRDLDSVLLLLFFCEVRQHHPTLLEKTE
SPTHWQEILKHYGSDTMLNNMSAGFAVSLTMSPFQVLGAFVDLVVKCRKFVGSKGCSSNT
EAKREVAASVEAVVALPSVTIELGGGGVECVICKEEMKEGRDVCELPCEHKFHWKCVLPW
VSKRNTCPCCRFLLPTDDVYGEIQRLWDAIFKLNTQHVSLGS
>Sgl47687 E3_activity/RING/U-box 69.8 0.0
MTTVAVAVNIGGNSRGNGSKRAVKWAVENLYSQSNHFVLVHVMPTITHIPTPSGNRISIT
ELDTKVVAKYMEDVREKTQAIFLQYKRLYKPGEFDFETLLLEHDNVAVALVDYVKTSSVR
SLVLGSESLNRFWRRIKGHRIPQSLLKSTPDTCDIFIVSKRRVKTKLASSMTSSAAIFTD
TQTESRRNGNDERPVIVTTGEIPLHSSSSIELSTGASHLSESSLSNSSPEAHERSNYNNV
HDDDLNAHAPSVISHTSTNTDLSSIGQMSLADSHVSYEQFDLNNEVEQLRLELQTTLALY
NRACEDLVHAQKKVRILSSECVVEAEKINAATEREENLRKFAEHEKLKHLQAEKDAQAAK
NLLAKESYERQIAELNALKEFKERQKIVDVLISNERRIRRYTTDEIKAATDNFSESKIIG
EGGYGKVYKGTLDHTRVAIKVLEHDATDKKEEFLREIRILSQLCHPNIVLLLGVCSEMGC
LVYEYMENGSLEEHIFRHNRRSPLPWFARFRIAFEIACGIAFLHRRKPEPIVHRDLKPGN
ILLGRNYVTKISDVGLAKLVSDNIPDSVTMFGNSLLAGTLYYIDPEYQRTGTVRPKSDLY
SFGIILLQLLTARSPNGLLLVMENAIASGTLSYILDDSVKDWPLAEVEELTKLALECCKL
RCRDRPDLETVVLPTLKKLADVADASMKVVQNSIFAPSHYFCPILHEVMDDPHVAGDGFT
YERRAIEAWLERHDISPVTKQKVAHFNLTPNMTLLTAIQEWKSRLASKHT
>Sgl47692 E3_activity/RING/RING 34.3 7.4
MSSTVPQQRSPTRNFNQYWCYQCQRVVRISSDNPSGVVCPRCNGHFISEMEIPRPRLVLD
FTYDDDVSSPHARLLEALALMLDPPVRVPTREQHDSLAIPQRPRVGSRENDVVLDGPNTG
RPRWVRAPRALARRDDWDLDLGVRPRPRSSWILVRPTGQPLGPAGPLPLPRPLPQDGLSN
ARNYYFGPGLQELIDELTENDRQGPPPAPDSAIEAVPTVKMEEQHAGDAGSDCPVCKEEL
EIGTEVRQLPCKHVYHSDCIVPWLRLHNSCPVCRTELPVVGDQGSSSGPIEIEGRRMIES
ENSSNNEDDVRPRRRCLNWRRLCSIWPFRSSYSRINPRDDDDGHDHNPRTSNAADQSRCR
IQ
>Sgl47701 E3_adaptor/Cullin_RING/DCX/DWD 79.4 9.9
MARGLKSSKKTKKKKSKGSTNGEASTSAASASLMPVKVWQPGVDAMGEDEELQCDPSAYN
SLHAFHADKPSLNSIGIFKVSNISGKRRDLVPKRDADGSDMDSDSDSDDDKDENELGPPI
LQLHKVAHQGCINRIRSMPQHPHISATWGDTGLVQVWDFSAHLNFSAESETGTSHQAPLS
VFRHKDEGYALDWNPLVPGRLVSGDCQNSIYLWEPVAESKWNVDKNPFIGHTASVEDLQW
SPYEDNVFASASVDKTIAIWDLRLGKSCATSFKAHDADVNVISWNRLASCMLASGSDDGS
FTIHDLRMVKQGDSSVAHFTYHKHPITSIEWSPHEGSTLAVTSADNQLTIWDLSLERDNE
EEEEFKAQTEDKVNAPEDLPPQLLFVHQGQKDLKELHWHLHIPGMIISTAADGFNILMPS
NIESNLPPANNA
>Sgl47711 E3_adaptor/Cullin_RING/SCF/F-box 12.5 0.1
MDTLPQQIIIDILSRLTNLSDIASCRLTCKTLNSLSSEISSINLLSSFDQYTQSRSQSSI
LPFKSNFIHFIRESDHLDSISIGVDDLLQSLVYDDVEDDGDDLHLSDEQFVSLWLPFVGC
QLKRLSLTDFWVQSCWRISC
>Sgl47749 E3_adaptor/Cullin_RING/DCX/DWD 78.2 11.0
MARGLKSSKKTKKKKSKSSTNGEASTSVASASLMPVKVWQPGVDAMGEDEELQCDPSAYN
SLHAFHVGWPCLSFDIVRDSLGLNRTEFPHTVFVVSGTQADKPSLNSIGIFKVSNISGKR
RDLVPKRDADGSDMDSDSDSDDDKDENELGPPILQLHKVAHQGCINRIRSMPQHPHISAT
WGDTGLVQVWDFSAHLNFSAESETGTSHQAPLSVFRHKDEGYALDWNPLVPGRLVSGDCQ
NSIYLWEPVAESKWNVDKNPFIGHTASVEDLQWSPYEDNVFASASVDKTIAIWDLRLGKS
CATSFKAHDADVNVISWNRLASCMLASGSDDGSFTIHDLRMVKQGDSSVAHFTYHKHPIT
SIEWSPHEGSTLAVTSADNQLTIWDLSLERDNEEEEEFKAQTEDKVNAPEDLPPQLLFVH
QGQKDLKELHWHLHIPGMIISTAADGFNILMPSNIESNLPPANNA
>Sgl47774 E3_adaptor/Cullin_RING/DCX/DWD 81 7.5
MSQNPNPNKSYEVPQPPTDSISSLNFSPRANHLIVTSWDNQVRCWEIMQSGTNVSSTPKA
VISHDQPVLCSAWKDDGTTVFSGGCDKQVKMWPLLSGGQPVTMAMHDAPIKDMAWIPEMS
LLVTGSWDKTLRYWDTRQPNPVHTQQLPERCYSLTVRHPLMVVGTADRNLVVFNLQNPQT
EFKRIMSPLKYQTRCLAAFPDKQGFLVGSIEGRVGVHHLDDAQSSKNFTFKCHREGNEIF
SVNSLNFHPIHGTFATAGSDGAFNFWDKDSKQRLKAMSRCSQPIPCSTFNHDGSIYAYSS
CYDWSKGAENHNPATAKTYIFLHLPQESEVKGKPRVGDTNKPSPEASKPGPDTNKPSPEA
SKRGPATTQPSPEASKPGPATSKPSLEASKPGPETS
>Sgl47809 E3_activity/RING/RING 31.5 9.9
MTSAAVLFYGRRSRSSRTFDDLGFGSSAPLPLSSSTADLSSSSNHHHHHHRHRHRRGDLH
RRHRHINFDDSDQFRHSFNASHVCGRTPIAESEPHQRDCNEESSSREINNRETVRGLNGR
YHRNNQLPGSVLLARERLVQRLRGVSVSGIRDARETAQSLPSNDQGVVDADWETSVSREE
SASYTNLTDVPVGAHQSVHREPQTKPRGLTDEALSKLHLEVFVEQQNLITQPMSKASTEC
SICLENFVEGNKLINLPCGHRFHTSCLYPWLQTCGECPYCRSCIMLT
>Sgl47818 E3_adaptor/Cullin_RING/DCX/DWD 52.4 4.2
MNSVLGLCWLKKYPSKLIAGSDSGSLRLYDVQQWQAAVTGRNFSASGFIFNDFDRLTSVH
VNATDELFVASGYSKNVALYDINTGKRVSVFSDMHQQHINVVKFSNHSPSVFATSSFDQD
VKMWDLRQGTIQPCFKASSSHGNVMVCFSPDDLYLLVSAVDNEVKQLSANDGRVLLDFEI
ASTGSSQNYTRSYYMNGRDYIISGSCDENIVRICCAQTGRRLRDISLEGRRSGASMFVQS
LRGDPFRDFNMSILAAYMRPSSNSEIIKVDPCLYSVH
>Sgl47828 E3_adaptor/Cullin_RING/DCX/DWD 82.4 7.3
MSAFSSLTNMSQNPNPNKSYEVPQPPTDSISSLNFSPRANHLIVTSWDNQVRCWEIMQSG
TNVSSTPKAVISHDQPVLCSAWKDDGTTVFSGGCDKQVKMWPLLSGGQPVTMAMHDAPIK
DMAWIPEMSLLVTGSWDKTLRYWDTRQPNPVHTQQLPERCYSLTVRHPLMVVGTADRNLV
VFNLQNPQTEFKRIMSPLKYQTRCLAAFPDKQGFLVGSIEGRVGVHHLDDAQSSKNFTFK
CHREGNEIFSVNSLNFHPIHGTFATAGSDGAFNFWDKDSKQRLKAMSRCSQPIPCSTFNH
DGSIYAYSSCYDWSKGAENHNPATAKTYIFLHLPQESEVKGKPRVGGTSRR
>Sgl47834 E3_activity/RING/RING 31.7 9.9
MEAPPIDFNGPFSEELMEYLHNPTQTRAFRMPYIQPPYPITLLITQDQKFLSTTPPYPTY
PESWINYEGSLQTRASTISTSLDNDQARYETSPHSGPNRCSSNVSSSGDTDEVVDGEAAE
GVRRPCHSLEVATTRRSSARVTKGQKSPRFELETGRSGLGKHDKQSLSXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXHSFNASHVCGRTPIAESEPHQRDCNEESSSREINNRETV
RGLNGRYHRNNQLPGSVLLARERLVQRLRGVSVSGIRDARETAQSLPSNDQGVVDADWET
SVSREESASYTNLTDVPVGAHQSVHREPQTKPRGLTDEALSKLHLEVFVEQQNLITQPMS
KASTECSICLENFVEGNKLINLPCGHRFHTSCLYPWLQTCGECPYCRSCIMLT
>Sgl47973 E3_adaptor/Cullin_RING/DCX/DWD 32.2 0.2
MLTSLQEGRAHRLAIDPGSPHVFYSCGEDGLVQHFDLRTKDFIELFTLCHSTFGRRRNSS
FVHLNAIAIDPRSPNLFAVGGSDDKQVEITGLAFSDISELLVSYNNENIYLFTKDMGWGP
NFAISSVSTCTDTAYEPEDDDPSEATKSVLDTNKKPLPQVYKGHHNCDTVKGVSFCGPKN
DYVVSGFDSGRIFIWRKKDGELIRIMEADRQLVNCIEAHPHTVVLASSGIESDIKIWTPK
AEERATLPANIYENGVPPPARHGRAIVEPDHKAWEGQKPISIVGSTGTIGTQDKCGKSRE
KLSTPSPSVITQAHPQPQALNHNAADDSTKDSPDGK
>Sgl48082 E3_adaptor/Cullin_RING/DCX/DWD 107.1 4.3
MAEVQKSEEATISFKNLFNREYHGHKKKVHSVAWNCTGTKLASGSVDQTARVWQIEPHSH
GKAKDIELKGHTDSVDQLCWDPKHADLLATASGDKTVRLWDARNGKCSQQAELSGENINI
TYKPDGTHIAVGNRDDELTILDVRKFKPIHRRKFNYEVNEIAWDMTGDKFFLTTGNGTVE
VLAYPSLKALDTLTAHTAGCYCIAIDPLGRYFAVGSADSLVSLWDIKEMLCVRTFVKLEW
PVRTLSFNHTGEYIASASEDLFIDIANVETGRSVHQIPCRAAMNSVEWNPKSNLLAYAGD
DKNKYQTDEGVFRIFGFQTA
>Sgl48184 E3_adaptor/Cullin_RING/DCX/DWD 64.4 11.2
MTAVAPPVVGQELSNPPTDGITNLRFSNHSDHLLVSSWDKTVRLYDASANVLRGEFKHGG
PVLDCCFHDDSSGFSASGDSTVRRLVFNQGKEDILGKHDAHVRCVEYSYTTGQVISGSWD
KTLKCWDPRGAGGPERTLVGTYIQPERVYSMSLVGHRVVVATAGRHVNVYDLRNMSQPEQ
RRESSLKYQTRCVRCYPNGTGYALSSVEGRVAMEFFDLSEAGQSKKYAFKCHRKSEAGRD
IVYPVNAIAFHPIYGTFATGGCDGIVNVWDGNNKKRLYQYAKYPTSISALSFSRDGHLLA
VASSYTFEEGNKPHEPDAIFVRSVNEVEVKPKPKVYANPPA
>Sgl48442 UBD/UBC-like/UBD_UBC 109.1 0.0
MKLCPREVEKLALHNDGFLAQKRLASGLRLNYTEAVALIATQVVVHSEKFYNFRSSVFID
FEFCSCWKQECGGTDGHWKEASWKRPSETPYDGGVFQLAFAVPEQYPLQPPQVRFLTKIF
HPNVHFKTGEVCLDILKNAWSPAWTLQSVCRAIIALMAHPEPDSPLNCDSGNLLRSGDLR
GFQSMAKMYTRLAAMPKKG
>Sgl48480 E3_activity/RING/RING 27 8.1
MMADEQELHPPKELSSSDSSIWDSLKVGVSPFVLGLSHSAPQFPSLSKHEGTVVEMGETR
VVIEVVMGLKKGWSMEWKLVFWECAVDLVLGKVGCSRVKKSPSRFWRREKGFLEMKEIEM
GEVRLLGYHRKNWILYHRRFVDVDLHATRKEVQCPICLGIIKKTRTVMECLHRFCRECID
KSMRMGNNECPACRTHCASRRSLRDDQRFDQLIVVLYPDIRKFEEEVMYELEDVDLQKIC
YEVPPKRKKKNVVFIWFQEVAFYDEDEARNKQIQESITQVLIKQSEALGKKRSSNKDAAG
ASVTRSQR
>Sgl48514 E3_adaptor/Cullin_RING/BCR/BTB 18.7 0.0
MKFMKLGSKPDTFQSEDKNVRYVATELATDIVIKVGDVKFYLHKFPLLSKSSWLQQLVSN
EQSNDEVIITDIPGGTAAFEICAKFCYGMVVTLNAHNVVAARCAAEYLGMHETMEKGNLA
YKIDVFLHSVIFRSWKDSIIVLHSTKSMLPWSEDLKLISQCVEFIASKAVTDTSKVDWSY
TYNRKKLPEETGTDPNWTGIRNKVVPNDWWVEDVCDLEVDLYKRVIVSINGKGIVCGEVI
GEALKAYTDRHFPSLIKGVNRSRDLTNYRSTVDTIIFLLPDEKGCVSCSFLLKLLKASIL
GDSAEVVKKELIKKIGHQLEQASVSELLIRAPEGETLMYDVDIVLNIVHEFLIRDQSSEI
ETLEAGEEAHEFKDPGILSEASKLMVAKLIDGYLAEISRDRNLPVSKFVELAEMVSSISR
PGHDGLYRAIDMYLKEHPEISKSDRKRICKFMDCKKLSVDACMHAVQNERLPMRVIVQVL
FFEQVRAAATSGTSTPDLPKSIRDLNNGSQRSSKSTPIADEDWDTVATAEELKALKSELA
TLKLERKKSEKVVEGRHSIDKAAFHKMKGVVMTKKIFSKLLSSKSANTHGGDTSGSDSSE
TPSSANPEDVKSTPSMNRRVSVS
>Sgl48594 E3_adaptor/Cullin_RING/DCX/DWD 107.1 4.3
MAEVQKSEEATISFKNLFNREYHGHKKKVHSVAWNCTGTKLASGSVDQTARVWQIEPHSH
GKAKDIELKGHTDSVDQLCWDPKHADLLATASGDKTVRLWDARNGKCSQQAELSGENINI
TYKPDGTHIAVGNRDDELTILDVRKFKPIHRRKFNYEVNEIAWDMTGDKFFLTTGNGTVE
VLAYPSLKALDTLTAHTAGCYCIAIDPLGRYFAVGSADSLVSLWDIKEMLCVRTFVKLEW
PVRTLSFNHTGEYIASASEDLFIDIANVETGRSVHQIPCRAAMNSVEWNPKSNLLAYAGD
DKNKYQTDEGVFRIFGFQTA
>Sgl48663 E3_adaptor/Cullin_RING/DCX/DWD 45.8 20.6
MIYGGRSFVSSRPAFSNDTKRLLICTGNTVSVFSTSTGMQITELEGHGSLVTSVVVVPSS
SKVLCYCWTSSLDGTIRYWDFSVPELIKTIDIRLPIFSMVIPSVLSKQDDEGGKPASVFA
YISVENMSDPDNKPKHLHGQIRKCNLTKSKLVSSVILKETAQPQFLTISPSGKLFAIQTK
RTLHIWKVPDDDSERALVKKMKLQHTKSFTTFAFHPNDSVVAAADVSGRILVWRGFSMRT
LLESNEQAKGKLTKYEDDKAGVRGENDAESCTTWHWHSSEVKFLAFSSDGVYLYSGGNEG
VLVLWQLDTGKKKFLPRIGSPLLYFVHSPDPTLSLISCSDNQIHILKMSSLEILKSITGI
KLPCSSPEIWSGLCGGLSFDCSAGIVALPTDNYRIQFYSLFDDTEISEVQICERNHQPSD
DIMVVVSLVALSHDGSLMSTVETRLAEDGVGGLVCLKFWATESRKEYKLSTIVYEPHRDA
AISAIAFRPGWKMVVSSSYGGDFKIWVQSDSTQSKSGIHTSGWVCHSVGAYKEKSMTAAT
FSADGSILAVAAETVITLWDPDRNYLVAVIGETYTPIVNLAFVGNSEYIVSTSHGTRPQL
SLWCLSKLSRTWSYDFHVEAVASMEDDTFFAVLAVIPESSISVESHGGSISSGDGIILLF
DTNSPTPTATWLVREAKGGGLAFLQGNNLSSLEDTNSSWRPAILLAYVSRDHEYVVFDPL
SKEQHKLNMNFKKGAMDSQEAERSGYASIYGELPHFDPKKTMQARILPSERPWETIFSGP
SHTLPPLTKLCSAFLESLLEKRTAATG
>Sgl48695 E3_adaptor/Cullin_RING/DCX/DWD 28 0.1
MLTNFETKSNRVKGLSFHSKRPWILASLHSGVIQLWDYRMGTLIDRFDEHDGPVRGVHFH
KSQPLLFVSGGILDRFYKRSDVPGLNWQYPTLLIDQNSKLGFAHFP
>Sgl48702 E3_adaptor/Cullin_RING/DCX/DWD 30.4 0.1
MLTNFETKSNRVKGLSFHSKRPWILASLHSGVIHLWDYRMGTLIDRFDEHDGPVRGVHFH
KSQPLFVSGGILDRFYKRSDVPGLNWQYPTLLIDQNSKLGFAHIP
>Sgl48704 E3_adaptor/Cullin_RING/DCX/DWD 13.6 3.0
MESMIDAHRLELVRNKCGFSDGVCLSSIGNSGGMGLWWKDINAHVISYSAHHFAVEVRDG
EGDPKWVAIGVYGWPESSNKHRTFELITQLRITINLPMVVFGDFNEILYESEKRGGAVRG
DNKMRLFRDVLCDCGLADLGFTGCPFTWQRVHAAIILNAEVEQRGRRRKKRFAFESLWLS
HEDFHATVKHAWDSNPMANLNEKVASCANDLSKWAWLTFGDIKKRIASKEEELVEWQRSV
PDASMLQNCKRLLCYFHHKASSRKRRNWIKKLEDEDGVSHTEEEKIGVIIANYFTNIFTS
TQPSTFEEAIAGLEELVTTEMNAALTQDPTPEEIHEALFQMHPTKSPGIDGMHALFFQKC
WHIMGGDITKFVLDWWRNGGNLNEANLTCIVLIPKCQEPKKMTDFRPINGTEYKADNPCT
TAQSWVSSITVCRNSDLAASGAGNGFVRLWTINSDNRGIEPLYDVPLVGYVNSLAIAKSG
KFLVAGVGQEPRLGRWDRIPTARNGVALQSFKLTS
>Sgl48935 DUB/USP 360.6 0.0
MNASWFIHRNRNLKGLQICEAALNLYFDEVQPILCGLIVDHRWWQNWLDYVNQDGMYGVN
DEPSPRSLDPADAWLSRRPSSIDNKYLIFESVSSDSNAAELHDTLVEGRDYILLPEEVWH
QLYNWYGGGPTLARKVINFGISQMELAVEVYPLRIQLFLTPKGDRSTIRISKKETIRELY
KRVCEIFNLDSEKIRIYDYYGKKKHALPTDLDKTLDDANIQMNQEILVEVLNNATSSIKS
NGTMRKQLNSFLLEPSKSGLSIAGGLSATKDVSTNCNLETSPGQNQVSPHRELNVVQETS
GVTTRGATAGLTGLVNLGNTCFMNSAIQCLVHTPEFARYFREDYRAEINRRNPMGMVGEL
ALAFGELLRKLWAPGRTPIAPKPFKAKLSRFAPQFSGYNQHDSQELLAFLLDGLHEDLNR
VKDKPYILSRDADGRPDEEVADEYWQNHKARNDSIIVDVCQGQYKSTLVCPVCAKVSVTF
DPFMYLSLPLQSTATRPLTVTIFSSDGRLLPNICTVTVPKQGRCRDLIQALSAACSLRPN
EKLLLAEIQNHLIHRFFEDPLTPLSNIKDEDHLAAYRIPLPAKGIIFLQLIHRLEDKGTV
NAQGVKGWKPYGTPLVSPIAYDDITTRGDVQTMVRTMLSPLLKEREKTSLSENDITPAVE
NSCDNFIKPVDSSESATWTERKNTETCGLEKLPLQLVDENNVCIDLSVGDEKLVNIPSSS
KSLLVFINWSKVLMEKYDTSYLENLPDVCKVGLPAKKARTEPLSLYSCLEAFLREEPLVS
EPDMWKCPQCEERRQASKKLDLWRLPNVLVIHLKRFSYNRSLKHKLDTFVNFPIYDLDLL
KYIANKNNSDPQLYELYALINHYGSMGSGHYTAHIKLIDENKWYSFDDNQISAINEEEVK
TNAAYVLFYRRKKVDA
>Sgl49057 E3_adaptor/Cullin_RING/DCX/DWD 48.9 0.4
MLSFVAAEQQDDYVSKLTGHKPEVCGLKWSYDNRELASGGNDNRLFVWNQHSTQPILKYS
EHTATVKAIAWSPHLHGLLASGGGTADRCIRFWNTTTNSQLGCVDTGSQVSFLNCFALLY
VW
>Sgl49203 E3_adaptor/Cullin_RING/DCX/DWD 58.7 1.2
MQLTRMTGVGKNDPTKTAWGTTRISIVNSMKPKATSPMTATVSDHQEAIHKKIFQSLCGH
TTPVESLAFDSAEVLVLGGASSGTVKLWDLEEAKSEFVYVLHFIYPPFVLLIKKLCNSLK
KVVRTLTGHRSNCTSVEFHPFGEFFASGSADTDLKIWDIRKKGCIHTYKGHTGGINTIKF
TPDGRWVVSGGFLFHFVRNHLR
>Sgl49279 E1 384.1 0.1
MGEPKIKYDRQLRIWGDQGQAALEKASVCLLNCGPTGSETLKNLVLGGIGSITVVDGSKV
EVGDLGNNFMVDESSLGESKAKCVCAFLQELNDAVKAKFIVEFPEKLIESNPSFFSQFTL
VIATQLVEEKMVRLDKICREANVKLIFARSYGLTGLVRVSVKEHSVIESKPDHFLDDLRL
NNPWAELKSFVESIDINVPDPVAHKHIPYVVILVKMAEEWAQSHSNTLPSTGEEKKAFKD
LLKSRMIGFDEDNYKEAVDASFKLFAPRGISPNLKWILQDSCAEIDSNSTDFWVMVAALK
EFINHEGAGEVPLEGSIPDMTSSTEHYVNLQKVYQAKAEADFLAMENHVQNLLKDIGRDP
SSLSKITIKIFCKNARKLKVCRYQTVEEEFNSPNVSELQKYFTDEEYSIAVGFYILLRAV
DRFAANYNCFPGQFDGEMDEDISRLKTQTVNLLNDLGCNSSVMTEDLINEICRFGASELH
AVATFIGGIASQEVIKLITKQFIPMTGTFVFNGIDQKSQLLVL
>Sgl49381 E3_adaptor/Cullin_RING/DCX/DWD 60.1 2.7
MSRPLSSSPNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNKLARSPSP
RGSNCSIESRESRFSDNDRNNFLDKPSSSHFPFCPTILPVPVQGPSTGQRASRALDLAPA
NVSTIPVVGDDDGSDDEGRIEDARTPEDCPILETAYNYYKANIKKYREYCDFGEGYKLGF
PKPTTVVELKYINLNNRGMEINLKSLPFDIDFHPSNSLVATGLINGYLLLHLYAADAEPQ
RLLKVRAHKNSCRAARFIHEGNAIVTGSPDCSILATDVETGSKIAHLQNAHTAPINRIMN
LTEATIASGDDAGCVKVWDTRQQSCCNTFEVHEEYISDMTFAPDSMKLLATSGDGTLSVC
SLRSNKVHAQSEFCEDEPLSVLIMKNGRKVVCGTQTGTLLLYSWGLFKDCSDRFVDLSPN
PVDALLKYDEDRIVTGSYNGLISLVGILPNQIIQPIAEHSEYPVERLAFSHDKKLLGSIS
HDNILKLWDMDGLLQGSNTLTRNDTTALDNDSNSDGMDVDSDLPKASKGTKRKNNGQASS
SSFGGFFADL
>Sgl49662 DUB/JAMM 33.2 2.8
MDRLTRMFAGAGGALGHPPPDSPTLDTSEQVYISSLALLKMLKHGRAGVPMEVMGLMLGE
FVDEYTVRVVDVFAMPQSGTGVSVEAVDHVFQTNMLDMLKQTGRPEMVVGWYHSHPGFGC
WLSGVDINTQQSFEALNQRAVAVVVDPIQSVKGKVVIDAFRLINPQSMMLGQEPRQTTSN
LGHLNKPSIQALIHGLNRHYYSIAINYRKNELEEMMLLNLHKKKWTDGLSLKRFDIHSKT
NEQTVQVSAVYINCSISELA
>Sgl49691 E3_adaptor/Cullin_RING/Cullin 633 4.4
MSPPNNNKRPSSSSSSSSSAINNNSNINLNNNHSNNNNNNNNNNNNLSSSSSYFPPMKKL
KPQNSSLDSKNGIHSSSLTDDDVVVNHGASMIVDDDLKPDAVVSPSSNSRPITAGVTANL
SRKKATPPNPSTKKLVIKLVKAKPTLPPNFEEDTWATLKSAINAIFLKQPDSCDLEKLYQ
AVNDLCLHKMGGSLYQRIEKECEAHVSTVLYSLVGQSPDLVVFLSLVEKCWQDLCDQMLM
IRGIALYLDRTYVKQNPSVKSLWDMGLQLFRKHLSLCPEVEHKTVTGLLRMIERERLGEA
VDRTLLNHLLKMFTALGIYQDSFEKPFLACTEEFYAAEGAKYMQQSDVPDYLKHVEIRLH
EEQERCLLYLDVSTRKPLITTAEKQLLERHISAILDKGFMMLMDGSRIDDLQRMYNLFSR
VDALESLRQALSSYIRKAGQATVMDEEKDKDMVSCLLEFKAALDKIWEESFSKNESFGNT
IKDSFEYLINLRQNRPAELIAKFLDEKLRAGNKGTSEEELEGTLDKVLVLFRFIQGKDVF
EAFYKKDLAKRLLLGKSASIDAEKSMISKLKTECGSQFTNKLEGMFKDIELSKEINESFK
QSSQARTKLPSGIEMSVHVLTTGYWPTYPPMDVRLPHELNVYQDIFKEFYLSKYSGRRLM
WQNSLGHCVLKADFPKGKKELAVSLFQAVVLMLFNDAEKLSFQDIKDATGIEDKELRRTL
QSLACGKVRVLQKNPKSRDVEDDDSFVFNDGFAAPLYRIKVNAIQMKETVEENTSTTERV
FQDRQYQVDAAIVRIMKTRKVLSHTLLITELFQQLKFPIKPADLKKRIESLIDREYLERD
KNNPQIYNYLA
>Sgl49813 E3_adaptor/Cullin_RING/BCR/BTB 23.9 0.0
MACVKLGSKSDAFQRNGQAWFCTTGLPSDIIVEVDEMSFHLHKFPLLSRSCVLERLIAES
DDGEVGSIISISDLPGGAKIFELVAKFCYGVKLELTASNVVYLRCAAEHLEMTEEYGEGN
LIFQTETFFTQAVLKNWKESLKALQTCDDILPCADELHITKRCIESLATKASTDPNLFGW
PVVERGGPMQSPGGSVLWNGISTGARPKNSTSDWWYDDVSTLSFRLYKRLISAMESRGLK
PEIVSGAIAYYARKFLPGLNRRQGDSSSRLGPHSMSSPPSEEDQKLLVEEIDKLLPVQKG
LVSAKFLFGLLRTAMILRADSNCISSLEKRVGMQLDQANLEDLLMPNFSYSMETLYNVDC
VQRILDHFLMMDQANGDASPCSIDDGQLIGSPSLTPITMVAKLIDGYLAEVAPDINLKLP
NFQALAAAVPEYGRPLDDGLYRAIDIYLKSHPWTSESEREQLCRLMDCQKLSLEACTHAA
QNERLPLRIVVQVLFFEQLQLRNSIAGCFLVSENLEGSRQLRSGVVGSNEGAGWATAVRE
NQVLKVGMDNMRMRVSELEMECSNMRSEIEKLGRVKGPSTWGNVSRKLGLGLKMKSQMCS
AEEGSVSNQSVVSGKGEKFPLLSRSCVLERLIAESDDGEVGSIISISDLPGGAKIFELVA
KFCYGVKLELTASNVVYLRCAAEHLEMTEEYGEGNLIFQTETFFTQAVLKNWKESLKALQ
TCDDILPCADELHITKRCIESLATKASTDPNLFGWPVVERGGPMQSPGGSVLWNGISTGA
RPKNSTSDWWYDDVSTLSFRLYKRLISAMESRGLKPEIVSGAIAYYARKFLPGLNRRQGD
SSSRLGPHSMSSPPSEEDQKLLVEEIDKLLPVQKGLVSAKFLFGLLRTAMILRADSNCIS
SLEKRVGMQLDQANLEDLLMPNFSYSMETLYNVDCVQRILDHFLMMDQANGDASPCSIDD
GQLIGSPSLTPITMVAKLIDGYLAEVAPDINLKLPNFQALAAAVPEYGRPLDDGLYRAID
IYLKSHPWTSESEREQLCRLMDCQKLSLEACTHAAQNERLPLRIVVQVLFFEQLQLRNSI
AGCFLVSENLEGSRQLRSGVVGSNEGAGWATAVRENQVLKVGMDNMRMRVSELEMECSNM
RSEIEKLGRVKGPSTWGNVSRKLGLGLKMKSQMCSAEEGSVSNQSVVSGKGEKVKEKCAK
TKKKL
>Sgl49831 DUB/JAMM 32.8 2.8
MDRLTRMFAGAGGALGHPPPDSPTLDTSEQVYISSLALLKMLKHGRAGVPMEVMGLMLGE
FVDEYTVRVVDVFAMPQSGTGVSVEAVDHVFQTNMLDMLKQTGRPEMVVGWYHSHPGFGC
WLSGVDINTQQSFEALNQRAVAVVVDPIQSVKGKVVIDAFRLINPQSMMLGQEPRQTTSN
LGHLNKPSIQALIHGLNRHYYSIAINYRKNELEEMMLLNLHKKKWTDGLSLKRFDIHSKT
NEQTVQEMLGLAVKYNKAVQEEDELPPEKLAIANVGRQDAKKHLEEHVSNLMSANIVQTL
GTMLDTVVF
>Sgl49856 E3_adaptor/Cullin_RING/DCX/DWD 21.7 1.4
MELQNLGVAICGKWIKRPEKNVNLVVLGKSYKSSSAKSKVEIFSFDPNNNCLSPTPVSEV
EIEDGEPISIAVHPNGEQIICTTTSGDCKLFDLRVIENSIKLSAREAPSLKGVGRQTCVA
FSIDGCKLGLGGENGRLRIIEWPSMRIIIDEADAHKSFRDMDFSLDSEFLASTSTDGAAR
VWNVNEGVPVATLKRNPDEKIELCCFSKDGTKPFLFCTIQRAKFKPTTAVWDMSTWKRIG
FKVLLAKPASVMSTSPDGKYIGMASKDGDFCIVEVKTMRINHWSKRLYPNTFIETLEFCP
TERVVLTTTKEMGFKITKLTVPADWKDWQIYGILVALLLVSAVAFYIFYLYSDSFWQAPD
SYQNFPHYNTIRSDPQSSEDPFGPLDL
>Sgl50011 E3_adaptor/Cullin_RING/SCF/F-box 17.4 0.2
MSTIEEPRNWLELPHDVILLILMKLECSHILETVQFVCKLWYSCCKDPSIWCTIVMNTSD
EFLCVGDDRWNKMLYNAVDRSCGGLIKLDLEGFSSDKSDNLITCVVQQSSQLKHFRLACC
YEISGHALIEALGKLPSLEVVELTLCSIASARTIDIINCCPSVKTFKLNKLPYMNRTCDD
EALAIAASMPGLIHLQLIGNIMTNAGLVAILDNCPQLQSLDLRACLHLHFAGNLAKRCSE
QIKDLRRPSDSTYDYNYPTTPRDYWDDAIYVDGPHDVDYMSDSDPMWL
>Sgl50015 E3_activity/RING/U-box 24.5 0.7
MADTLYLEKMGRELKCPICLSLLNSAASLTCNHVFCNSCIQKSMKSGASCPVCKVPYQRR
EIRPAPHMDNLVNIYKSMEGASGVTLHVTQNEPTTKMADAEKHAGHRLDITENDGKNQEL
VECQRTEGTSSIASKLKPKRSGRNRGKSSFAMNKRVQMPESPTSETPIREMKDGLSQSRV
INTIMNKCSTFSSENPIPIENERPNLSPFFWLREEVERTSQQTDGEQLTLSCTPEKGPSF
SDLKDSDDELPLDISSKEQRNKCNADVFDSEMFEWTQRECSPELCSSPFKQQDEEPDCDT
MGEPMEAASRDAVADSKLITENLTNVSLQENTSTMDNKLLKDLFSKRKGQDSRNGPKVPY
KKGGKKIKQSKKKCRKNNMEIDEAFENPKTPDELMQCKGFDAELVLGDAEAAGTSKTGQN
QSFDVSIMNEADNHVVPESPVASRSKRGTNKNKKLENIKRRLDSIKASNEGQLVKRKKQK
KNLAQPVVNTEKSIPSNEMLLEKPCRVRKKLSSCSTSNKPNEICQLAAVKQKYSLDKNAR
GKNVGGEAAAQVAVASAQAKSNNDNSGNSLKRGKVHGNKDIPSLRKCDTVSVKCAFCHST
EETEATGEMAHYSEGRPVAANHSGGSVIHSHKYCTEWAPNVYFEDNMVVNLEEELTRSRR
IKCSLCGVKGAALGCYEKSCRKSFHVPCAKMLRECRWDTDHFVILCPLHAPSKLPSELPA
PQVRKRNCNFEGKIPCQKPPVAARQATSTAKWNCVRPSEKVVLCCSALATTEKDAVSKLA
KSSGAVVFKNWNPSVTHVIASTDENGACRRTLKVLMGILEGKWILSIRWIQACKEAMRLV
EEAPYEINCDIHGVRNGPRLGRLRLLNEQPKLFSGFNFYFMGDFEPSYKGYLQDLVTAAG
GTVLHRKPIAQTQGVNVPSSSASSTVIVYSIELPANCDIDKDVVLDRRHFDAEALAMSCG
AKLANNSWVLNCIAGHKLLDH
>Sgl50022 E3_adaptor/Cullin_RING/DCX/DWD 90.5 8.0
MRPILMKGHERPLTFLKYNRDGDLLFSCAKDHNPTVWFADNGERLGTYRGHNGAVWSCDV
SWDSSRLLTGSADTTVKLWDVKKGEQLFTFNFDSPARSVDFSVGDKLAVMTTDPFMEKTS
AIHIKRIAEDIEDQDKESALVIRGPSGRINRAVWGPLNKTIISCGEDAIIRVWDPVTGQE
IMSTKDHESGHKQAITSLSMSADKSHFLTGALDKSAKLWDTRTLTLIKTYGTERPVNAVT
MSPLLDHVVLGGGQEASSVTTTDHRAGKFEAKFYDKILQEEIGGVKGHFGPINALAFNPD
GKSFASGGEDGYVRLHHFDPDYFNIKL
>Sgl50025 E3_adaptor/Cullin_RING/SCF/F-box 20.7 0.1
MESEFTNAETLAMASSDMEVTPSSSLSLPSAIEEPRNWLELPRDVTLLILMKLNTFEILE
SAQFVCKLWYNCCKDPSMWRTIVMHNLDEHESVEKHQKMLYNAVDRSSGGLIKLDIEGFG
CDDLIIYIAQRSNQLKLLRLACCYAVSADALIEAFGKLPSLEEVELTLCSFTAAQTINII
HCCPSLKTFKLNEQGSRNPTMACDDEALAIAESMPGLNHLQLIGNSMTNVGLKAILDNCP
HLQSLDMRACFHIHLAGSLAKRCAEQIKDLRCPYDSTEDYSYLTTDYDSDFDEIYPDDYD
DLDFVSDDDYYEFSDDNDGHLYADVYDF
>Sgl50149 E3_adaptor/Cullin_RING/SCF/F-box 13.8 0.1
MKNCVKRKRSCNIITLKSESKEDRLSELPDEIIIEIISLLPIRSAAATSVLSRRWRNLWT
QIHSIDVRQSEFNNSRNIDIKYYCFFNIIEDIVLEKVTSTTIERFSVSLGASPTYHLHSW
LNKICCRNVKEIKVECKSRVVEPFTLTVSNVVLQTVSLVVLDIGEGFDFYYFPSDDYVDR
VISIINLPRLKKLRYSNFAGNAKFLENLVSSCPLLEDLFIKVVYLDPQNKVFKLSCHNLK
VLELEYDKNKYIQRREGVYTTKFVIDAPKLEYFSARAYRFEDLRFKFVGNPTALLHRTRL
MRTYNIWNSLVWVNPSSNFFKTTSLELDCIRVRPLRAFPNLTRLELRWPLDNDWSVLIRF
LRYCPALDVLMLNIVSVYNVKNLRWTPSSRSSAFETPANPPPCLQTRLKKIELKIERRIH
YREQLINMVRYLLRNFFVLEQFTFRIDNRDDCKIKDKSRFQSYERKVCEEMFSLPERSSR
CQINFVGEYHKASTNKARTVQGS
>Sgl50189 E3_activity/RING/RING 30.5 3.2
MGNAIHMNCSHDTLATSSSKDSSSPPKHIITSYITSVSYHRVVYHNNNTTSDGRRYTRFV
SRTEQPNPNVYRCSKPLNPLCVFCRKDIFALLLNSEYLRKEAHDELKRFSHEVRTKVKSM
RSDINKNNKHAKDKDKDNDNAAIVIYHQIHKHGLPDRVIDQEEYMRLLAKGVVFDEEVVP
IARPASELAIRGLQRVVLSNDKLVSNDEDNNMCSICLQELVIMKKEENYNDKDDNEELIN
KSSVVRLLCKHMFHEGCVVKWLRRSHVCPNCRFKLPLAS
>Sgl50221 E3_adaptor/Cullin_RING/DCX/DWD 56.4 9.0
METYNTKSILHHINSRELHGFKEKGSYLVIEPQLMSLAVVEVFPVHISMFLHTPPLAVSF
ANTIKNAHILGVTDEEGYVNLINTHSKLDPSATNQENAAKVVVSSWVVHDNSVYDICWIK
EDMNVLTASADHSIKLWDVEQKKCHGTLRGHVGSLLSFANIFCWFLCYPLDLVVSGSRDG
FFMLWDLRCSPQRGRHWMMQTEQVNGAHASVKRKRFTRKKAASNPSMMVTSVLYLKDDVS
IVTEGVVDSCAIQEIFELQLFKLVRFRRLQQRRMGDYMELPAYPKIEMESCFLHLVPIIE
YIYIMFSNSKRVQSAPSLEVKLDHFISSPDASHILSGSADGNAYIWQVDRPHQDPISLTR
HEKKVTAVDWYVTNIYEVRFWDIQNRNYLLPRISTTRHKRVVKAPRTECIEEKEPSPQRE
SPCNSSGKEAGSVLFNLL
>Sgl50300 E3_adaptor/Cullin_RING/DCX/DWD 60 10.4
MEASGVPRRLKGHTATATSCIASRQRPRVIFTAAEDGCMCLFDLRCKEVQQIMKLGNDAI
SSLCFKEGNENMIYLSSGTEVRCFDVQMIVQALILASLFISSVRLQISCNSKSSFLAAAD
DSGDVKIIDIQRRCPFKTLRSGHASICSSVQFVPWKPWEVITGGLDSKMIMWDFSKGRPF
LVVDFGNVEETSKNSGQFCNPAFIHAIAVPDMDMLDKLGKTCAIARGDGIVSLINIEAEL
AADKSKGAAKPRKNSQGGSSSATGGPDADTENQNKAKRLHLDHTLEGHTAAASCVTYSSF
GERGKFIISGGNDKTVKVWDWSRHLDETQPKADTAAVSSINLPKKVNWLCTTPTDSENLV
VCDTSKVVKVYSLA
>Sgl50357 E3_activity/RING/U-box 114.3 0.0
MATSAAFSSLRRRRSPPLEAFLAPVDLTDRGIIKTLLSVANELVELHSGKKLPFQKKNFL
SLVRKIEVFVVLLDYLKEYRPISRFSYTEIMCFKELYLLFYRCKILLDYCAQSSKLWMLL
QNQSISGHFHDLNQEISTLLDVLPIRDFGLSEDVREQIEMLKRQLSRAKGYVDKKDEMLR
NRLYSFLNEFEDGKVPHLTELSNFFIDQLRIFDAKSCRAEIEFLEEQIVNHEGDVEPTAS
VLNGFVALTRYCRFLLFRFEEEEMEVVVESIKKMRKAMISQEIADTFLTIPKDFSCPISL
ELMRDPVIVSTGQTYDRSSISRWLDEGHYTCPKTGQMLAHTRLIPNRALRNLIAQWSAAH
GVPFEPLEGAESSSELAAAASSKAAVAANQATAYLLIQKLASGSGDAQAIAAREIRLLAK
TGKENRAFIAEAGAVPHLKRLLSSANAVAQENSVTAMLNLSIYDKNKAKIMDEVGCLKSI
VDVLRFGHTTEARENAAATLFSLSAVHDYKKRIADENGAVEALADLLRYGTPRGKKDAIT
ALFNLSTHTENCVRMIESGAVTAVVEALGVDGVSEEAAGALALIVRQSAGAAAVGREETA
VAGLIGMMRGGTPRGKENAVAALLELCRCGGAAATERVLKAPALASLLQTLLFTGTKRAR
RKAASLARVFQRRENAAMHYGGLRVGHQLAGNSVPNRDPSFVGDVSVPMSISVPVVQG
>Sgl50369 UBD/UBC-like/UBD_UBC 136.5 0.0
MQASRARLFKEYKEVQREKTADPDIQLACDDSNIFKWTALIKGPSETPYEGGVFQLAFAV
PEQYPLQPPQVRFLTKIFHPNVHFKTGEICLDILKNAWSPAWTLQSVCRAIIALMAHPEP
DSPLNCDSGNLLRSGDLRGFQSMAKMYTRLAAMPKKG
>Sgl50423 E3_adaptor/Cullin_RING/SCF/F-box 32.6 0.0
MADYLPAPLVTEILSRLPAKSLLRFRCVSKTWKSLIDGPNLIKLHLKNSLQNTTNHTIIL
RHFSLFYLGFPTLNQVKEINHPLKSDCYGTEVVGSCNGLLCLSNGEEHGIEGTIIYNPAT
KKSRELPVSPIEFPKDDIFPFCERLVYGLGYDKGCDDYKLVRICQFYCGNPDFYDSEVKV
YSLKMNSWRRVMDFPKEYFLSYKRVSGVFVNGCLHWVVSKNPESDGAKSIIAFDLGSGRC
RIVSKPRALCGTCHINVDVLCGSLSVLVSHPEIRSEVWIMERYGVEGSWTKLFSIAYGSV
LGNFEYVRALVCSSDGSRLLLQKDMKSLFWYDLRTQRAKRVNVHGLPDWFEAQMLVESLV
PLDGYKKSKKKKPKRKRTELSEQADSLFTMLPEPLLLNIFSRLPADTLLQLTYVCKAWNN
VINDPEFAKMHLEVSAKCNENLNFVLGHEKLHLIDFNKLNAAVQTNHPLVYPKGWTSVLG
ACNGLLCLYNREKDLAIWNPLTGRCHKIPIKETKSPNSYDMHFYMYGFGFDSSSDDYKVV
QIFQMHSFKGPSHDYFGSDSSDSESDICYGSEVQVYSLKDKCWRKIKCFPFTLSYVCPGV
FVNGALYWVADAKRGMDSISNVILSFDLGSEECRVVPQPDYGNLNFHLSLWLFGGSLCIL
CHYPRHGVDIWVMEDYEMQTWCKLISITQPKPIKYFEYIKPLTYSKNGSEVLLEXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXX
>Sgl50425 E3_adaptor/Cullin_RING/SCF/F-box 13.1 0.0
MAENNCDRFSNLPEELIHHIFSKFSYNEMNSMMNVSKKLQNLCFSSSTMAFGAYLHHPSS
TALDFRDFVDEFLAKASFRLTNSTTPLLRSLCLTWRRGKDGRKLHCSQALPQSSLASCVE
TLVVNYYKIELLEASNFGEWISSSFPCVKKLVVRFEDCSFGTNQTLSIDHCPTLEEIEVS
GPENSTYDHNLRLKIISCSSLEHLTIKNLRFEEATCEITIMGEQLRTLSIDGAMLLNCSS
LAHVFKIHAPNLRVFHWRGSAIKYFVDSTNSFQHLEKAVLDVKGKHKLLYYKFVNKLLSS
LQHAIHLEWRSTSKDYVFRELHFKVRRNHMVKIM
>Sgl50436 E3_activity/RING/U-box 103.6 0.2
MGNELPEYFKCPISLEIMVDPVILSSGHTFDRTSIQRWLDSGHRTCPITKLPLPNHPPLL
IPNHALRSLISNYAPPHHRLSTIGSEANSISQLAPLIEALVSKSSTEVEKVESITRLLAV
SKAHPGEFRARATDSGGLSAVLRCIGPECGPDLQEKSLSLLLNLSLDSDDNKVGLMAEGV
MEKLTAALVGPNAATAATLITSLATLEVNKAAIGAHPGAIRGLVTLMGGGRREKKEAATA
VFALCSFPENRRRAVDCGAVRVSLSMAKSGAERAVEVMGMLAKCTRGREELVRCCEEVVG
VLVWFVKNGSSRGVQYGLMTLNLISCCSERVKVEVRRFGVLEMCFGFMEEHYGNEKIIKV
ASNLAKVLQEN
>Sgl50446 E3_adaptor/Cullin_RING/SCF/F-box 18.1 0.0
MESQRLHEDVLMEILVRLPVKSLVRFTCVCKYWLSIIKSPDFATKHYAARLDRLRYLSHN
YDCFLTIRSRACSIFICNTVNMALETAFKFRPAVTYEPPRFEIGHYKVIKDYLIYGPCNG
LFVINLFIHKREQPVLLLWNPATRKVFKLPENKYNYHGNDCVALGFDHVTNDYKVISFLS
PSCTEDPMSLNSKGNSRLIPWYSLATNSWRQVDGGFDFNHLKKSVYCKPSNTSSSLNGRK
NHFLLGDSYPFPNGINPTFSLLTFDMVDEVFVETAMPDEITTNDLSFDGFLHQGSSHDTR
YPTIYSFGFNKAGQSDYDPIEVHIWVLEGYGRTGFWKKQQSIILSEYSWGNAKVAFWKIT
SYHFTTEYLTSVRKILGDGGTIIGYNESLVSIASKLPSPANHLSVETNDDTSCPQSVDTG
PPELMQDDDHDPSLSAQILENREEEEEEDDDKSSTDSAFLIPPRRDPSRMFDIEYDIQRR
TEQERLCQLPYCLREVKQPMKNNPYTF
>Sgl50449 E3_adaptor/Cullin_RING/SCF/F-box 12.3 0.0
MLDQVKRSEMGDCISELPDDVLCYILSFLTVRDAVRARSLSRRWRYLPYHCPTVLRFDAL
NVLGNERYSCVSHQSKFVRLVDHLMDTFTLRPSVLKLQFHLDKLYSSNIDTWIVRFVTMG
IKELDLFIPNYVFSCYLLCPWMEASSLTCLRLSFCALNLSSCCTSWISQLTTLQMSAVSM
DCNDMEFILSSALNVTSLSLAYCCNPTIQCLKVELLGLKKLFIEELLMDLKLNCPNLEVF
EFTGRLSNITLAHLPFLRQAKVFPNLHRDGGSLIFAELIRFAPHLKALSFSVMTVVQVQP
LPFEARTINSSLKQLDLLMFVPYCFDLFSITCFINACPSLEILRLKLKPGSDPRQSPEKE
YPDCQHNKLKEVEIDGHSERFNSLELALYLLRNAVALEKMVIVCPDRINNNKARLTTLLQ
NANSSVELIIQCFS
>Sgl50463 E3_activity/RING/RING 20.6 23.7
MPQRHSKNNNDLAFFTYDEKRKLGYGTQKERLGKDSIKPFDACCLCLKPVIDPLCCPKGH
IFCKECILECLLSQKKDIQRKLAAHSVQKKQEKDEQEDKLMLQKARELEAFDQQNHGAVP
HQSDKSYYHNKNGFQGANSVKATSFEEEALRTMKAFWLPSATPEAPAKVEAPSTSTTCPE
GSEKLKLKSLFPVYFTEENDDDNKSKVFDKKHICPSCKVTLTNAMSLVALSSCGHVFCKK
CADKFVVVDKVCLVCDKPCKEKSLVSLKKGGTGFAGHDENLEAKDFKHLGSGSGLGLVRP
AQKV
>Sgl50493 E3_adaptor/Cullin_RING/SCF/F-box 14 0.0
MCSKKFKDSSKSETLHNISSFPDEVLEKVLGLLESHKDRSSVSLVCKDWYNAERWSRTHV
FIGNCYSVTPEIVARRFPKIRSVILKGKPRFSDFNLVPENWGADIHPWLLCFAKAYPFLE
ELRLKRMSVSDESLEFLALNFPNFKRISLLSCDGFSTDGLAAIATHCKNLVELDIQENGI
DDRSGSWLSCFPENFISLEILNFSNLNSEVSFSSLLRLVGRCKSMRVLKVNKYVNLEQLQ
RLLIQAPRLTQLGTGAFSQELQPSQYASLENIFNNYRSLQTICGLWETNSLYLSVLYPAC
SGLTFLNLSEAALQCDELAQLLNHCPNLRRLWVMDTVGDKGLEAVGSSCPLLEELRVFPA
SPFEADIGQGVTETGFVAVSYGCPKLHYVLYFCREMTNAAVATIVQNCPDFTHFRLCIMN
PGEPDHLTNEPMDEAFGSVVKSCKKLKRLALSGLLTDLTFEYIGKYAKNLETLSVAFAGS
SDLGMQCVLAGCPKLRRLEIRDCPFGNSALLSGLERYESMRSLWMSACNVTMSACRRLAT
EMPRLNVEVIKDEDTDECNANKVYVYRSVAGPRKDAPPFVLTL
>Sgl50504 E3_adaptor/Cullin_RING/DCX/DWD 81.3 9.4
MAENHSQLQHNENQEDEQHQFVETNALQIENDETFEVDDTNSNDHQGQVYSWPQIQFDVQ
PYKSCHFYRQFRSSSNPNNFLKSVKWSPDGSCFLTSSEDSTLRIFSLPDNDYLAGSIASG
PDEDSYAAKLVINEGESVYDYCWYPYMSASDTTSCVFATTTRDHPVHLWDSTTGELRCTY
RAYDAMDEITAAFSIAFNPTGTKIFAGYNKTMRVFDVHRPGRDFAQHSTLQRSKEGQSGI
ISAIAFSSAHSGMLATGSYDQTTAIYREDNMELLYVLHGQEGGVTHVQFSKDGNYLYTGA
RKDPYIMCWDVRNTVEVVYKLYRSTEQTNQRISFDIEPIGRHLATGGQDGLVHIYDLQTG
QWTSSFAAASDTVNGFSFHPFLPMAVSSSGHRRFGLPDDADDTVVPLSSDENCASVWSFS
YTSATENPMSINGEDSLGMLEDEKP
>Sgl50510 E3_adaptor/Cullin_RING/DCX/DWD 16 0.0
MEADDSERVLPFQLQFDKPAPSQIKMAEWNPEKDLLALVTDDSKIILHRFNWQRLWTISP
GKCITSLCWRPDGKAVAVGLEDGTISLHDVENGKLLRSVKSHNVAVVCLNWVEDDGHGQD
NRENTMPFEDRSLRFFPPAPRVPRIPGVVSGDSTLMDSTEDSFQDLLNTSRQRFNILCSA
DKDGGICFSIFGIFPIGKINIQSLSLPLISNQVAYQIIHASINKVALSKDFCRLIVVCSG
ELVSSSSEVNHEPLSRPETEGMHCLVLDTSVFQKRKQELHQVAQQVSSIEDLTEVIRASL
SIMYKQWSDAMQMFHDKFNSLSTLIVSNGLDSSPQDEFLSLLGGARTSPPIHQFLVNSLG
ESGLKRVTKAVSNAGKELQLILLDHIQPAAEIIGYRMGELRGLSRWRARYGGIGLDEKLI
DNGTEKVGMLLVQVVRFVQILSSVTQQFSNFFSWLLRCIKILMSEPSDQLPSYNSELVII
FLKFLYDRDPVKLLLDQSVDQSVQLNLDTKQRVEELVKLGGFADTECLHRTLAKEFQYME
SSFKEAFNMPYTTISKKIVCEQMLPLYPFRSSPPSTPISFPTSISFYWDAAPDVSTCETS
QENLVDYIAFQIPECSSSDASNCILILRGIINEADNVKSSYTTVDALLLSVSREFSCIDL
SLYKERQLILLLNETTAASDSSGNALLMMIQTSDLPFVSISTSTSLKFWNSDQLQDCILP
VQTESAKVRSIPHNVVSPLAVSSSRGVGCVFAARKRALVYILDEDEEEEEEETSDMD
>Sgl50520 E3_adaptor/Cullin_RING/SCF/F-box 15.1 0.0
MEGENDYISDLPDAILHQILSLIPTKLVVSSSCVSKRWGEISAGFFRYAHTFQFDEEFAK
QQTPDQLTENINRILSLNKSEKIRKFKLVFSPTIENMFDVTNWILFATGKDVEELDLDFL
FPTHFLSPVDAVDLEDVFVLPNFMFDCKTLETVKLSRCILGLPEQYTGFRGIQTLCLSQV
HVTDSMLGSLLSNCTLLEVLVLKECGALTSIRIRSHSHTRLQRLTVYECNNASFIEISGP
KIRSLLISASTLKDCTLEDMFVLEEVLVGTRGYELYDAVDGIKYVKLFGQLKHVKTMYIN
LSHSVPSWIDGFRVPFKNLRELHLVNSPLFGLFKSGVCSLLWCPSLEKLTIELPTVSEEE
NFSWVCTDPPDSPRKEREFNSLRTVTFRNFRGTDADFELATHVLERAPSLESILLIAPQN
LNAQKVTAKDEVSSFWTLKIKETELWLWQKGIFEKFRYFPKVSEIADIQASEGDEHDISL
LSFFDLHYVSDVYNN
>Sgl50521 E3_adaptor/Cullin_RING/SCF/F-box 20.1 0.0
MEEGEKDYISDLPDAILHQILSLIPTKFVVSSSSVSKRWREISADHLLFASALEFGEEFA
KQQTPDQLTETLTRILSLNKSEKILKLKLVFSPRNEEHMVNATNWILFATCKGVRELDLD
FCRHIYIHFLSPAHVVGKKDVFALPNFLFNCKTLETVRLSRCILDLPEEYTGFRGIQTLC
LKEVHVTDSMLESLLSNCTLLEVLVLKECGALTSIRIRSHTRLQRLTVYECYNAMIIEIS
GPKIRSLLISAGHLDACKLEDMFMLEEVFVGTRGDEFGGVFSIFIKVFSQLAHVRTLSLY
LGHLVPNLIKDFKVKFGNLRELHLVNSPLFGMFNSDVYCFFRHCSCPVLQKITIELSTVS
EEENFIWEFRKPNIKPKERVFKSLRTITFRNFRGTNADIELATHFLERAPSLESMLLIAP
QNLNSQKVAAKDEVSFSALKEKETKVWQKAVCEKLRYLPKASEIADIRVCEGDEYDDGLL
SFFNWHHVSDVYYK
>Sgl50534 E3_adaptor/Cullin_RING/DCX/DWD 120 6.8
MAKRSYKLQEFVAHSGNVNCLRIGKKACRLLLTGGDDNKVNLWAIGKPTSLMSLCGHTTP
VESLAFDSAEVLVLGGASSGTVKLWDLEEAKMVRTLTGHRSNCTSVEFHPFGEFFASGSA
DTDLKIWDIRKKGCIHTYKGHTGGINTIKFTPDGRWVVSGGFDNVVKVWDLTAGKLLHDF
KFHDGHIRSLDFHPLEFLLATGSADRTVQFWDLETFEMIGSARAEATGVRAMTFHPDGRT
LFCGYENNFKVYSWEPVICHDAIDMGWSTLGDLCINEGKLIGCSYYRNSVGAWVADLSRV
KPYGTGDSGESQERSPVGKVGKRETPTAEGVEPVVRSSLSSRSTSPDADAKEIKNIYVDY
EKPVSFRKARSLNASKTELRSDSKQSSKLSSRKQNTPNTASGRSNGQVGGRSFTAPSFVP
RESSSGKAYSSSRRESITPMKHGGGGAIKAAHSRKYSHSKFDIDDADPNFLDRLVQEVGA
MELDEDKNPTPESAEEKFEEKTSLPSASNPRSEGGNPVDGKEVPNTKVVNRVALGRTRSL
VEKFERRGKFDGDEDQTVSASPDIIADRINSSTMLKEEPQVSGRDSASASDSYIIEDLME
NHDVILSGLRSRLTKLQMVRHLWERNDIKGAITSLKKLPDHSVQADVISILMEKMEIVTM
DLFSCLLPILVGLLDSKIERHAKMTLEMLLKLIAQFGPTIRSTISAPPSVGVDLHQEERI
ACCKQSFVQLQQIQGLLPALARRGGSLAKSALELNLVLQDHSI
>Sgl50546 E3_adaptor/Cullin_RING/SCF/F-box 15 0.0
MPEVESSRISSDSPEVSSTSVIHSDPFLITNSDSPTASLVATLFNGSNFVRWNRNVRRSL
AAKNKEGFINGDLLEPDLADPNYKKWKRADYMVLQWILSSMTPDLADDFSYMERSIDLWL
ELQERFGQSNGPLVYQLKKDLDALKQENLSILSYYGKVKKLWDEMTSIHSLPICSCGALK
SCTCHFLKKLADFESNEKLMQFLLGLNSAYDATVSTILASDPLPTLNRAFSITQQIEKQK
EVTGSFDGQIESSALAVTRSSKSSGGRPPSGPPNGARKKDWRKDRLERRCDHCKGTGHTI
DQCFKLIGYPDWYTAIKPGVKPSDSGPKLAATVATSSHLDAGLETPLDDAAGGLDSQMLN
AICKEVMKAMKGKGSADSSVGHSFTSFAAGITSVSPIISHTKNSNTWIVDTGASDHMIFD
STLFLDSYTLPTPMRVGLPDGTHKLISTAGSVRISPDLLLPNVLLVPGFHHNLLSVSRLT
SHLGIRVGFNNYGFWFQDPHTDRILAQGSQADGLYLLHTNKDTSFVASSVPESVSPIFVL
PNKTATSIDQKPRPSIDLHILHARLGHLSLSKMLHIPDCNCTGLTEYNCEICHCAKFHKF
PFSLSTSRAAHCFDLIHIDLWGPYKVAAIGGAKYFLTIVDDHSRTTWTFLLNNKTQVASC
VANFLSMVYTQFGTLIKYIRSDNGTELIKEQCITLFASKGIIHQKSVPHVPQQNSRVERK
HKHLLEVSRALRLHANLPKKFWGDCVLSATYIINKLPTKVLNWKSPSEILFNKPPDYSNL
RTIGCLCYAHDHRTKDKLDPKARKCIFLGYPLGQKAYKLYDLSQHTTFVSRDVTFYETVF
PFHSTSPDPIISAPTPSLISFGNDNDITVPSASPSNDGDNVPSHTQPLSPTPVPVQSPLS
PPHSPISPSSPAPVRKSTRQIKLPDKLNQFLVPYHPTNDSSSNGSTLSTLLYNPSTREKW
DIPDSPVDIPGYVVLCDRIVYGFGFDHVNDDYKLLRIIQSREKTVDFHVTEVKVFSLKSN
CWKRVKDFPKEYYISYGMCWGIHVCGCLHWLAIRKPDREKVIVAFDLGTEEYKVVPQPKY
FGGGKDCFVVEGVLDGCLMMQALYPKNRTDVWVMKEYGVKKSWTKLFTIPQWGCIGFYEA
LKPIVYVKENGSVKVLVEKNFKELIWIDLRKQKAESVKTLGIPWSFDAVLLLESLVPLNN
HRKKPVKKKKKKQRNNSVPSQNVQPVVAFPEKVLCHIFSWLPVNTLLQAQCVCKTWYNLI
NGTEFNTMYLENQSKCSSSLSLILKGDVFFSVNVQLLDKVSKVNHPLLCNEEYTDIVGCC
NGLVCVCADLNLALWNPWTGKHEKVCCPDFQLVHSSNVFRCLIHGFGYDPTTNDYKILSI
LQQYSQLKGGTVDTEVQVYSLKTKSWKRIQHFPYFVSYPSSGVFTNGALHWVARPIPDLY
SSSNLLLAFDLGVEKFRVVTQPNYVDTDFQMSLGLLGNRLCFLCHYPKESVDVWIMTDYY
NESWTKLICISQPSVIRRFQFMKPLAYSQDGSEVLFEQDNEKLLWYNLKKKTVKYINMPD
LPKVFYSVICSGSFVPIGNATRNYQVVDEKPSKEFQKSRNTKERHNLDGFLTKGFKLKL
>Sgl50547 E3_adaptor/Cullin_RING/SCF/F-box 13.2 0.0
MDQISFISPLIMADHLSELLVSEILSHLPVKSLLRFRCVSKPWKSLIDSKYFINLHLKNS
SKTPNKLVTQYGIVKINKKIGRDPFIYVVDFPTLDNPIVINKYDCPFYCSCRTKFYGSCN
GLIHLVNTVGYKRQISYICNPFRSTRKFRVIPESETDLQCSRVFYGFGYDSINDDYKIVQ
IVTLLSWTAPRTDTDTDTDTFCCNSKVNVFSFKDNCWKDVGYLPKYYIDYKVEAAIYFNG
CLHWIASDVPYLGTSRLMLVFDLGTEKFSVMPLPELAGSSRGMSKSCYINVGVLKGCICI
WECCDVSPPSLLKIDVWIMKEYGVNESWINLFSIDLNKFSSRLKNHCDYNCWRYIGYRKM
NGFEQVLINYQHSFAWYDVQQETVTFVRTEGFFHGLIAMLLVESLVPLESHT
>Sgl50552 E3_activity/RING/RING 17 9.5
MMMAEETLNLGLMNDFDFSDDDDDGFGIDADAFFNILNEDNPDQSPFPIDPFYPSTDNTL
ESGSAIHVNDHLNIPSQTDYGAASENSAETVEVMDQLPHSSSPEMVLSEVNDTSFSKEST
EVNAFQLSNYANTEFLPFGQDWQSMLQMSSANHPNSLAGLSHDVMSTNEAMRGNMTSDLD
DSRSSHPWSDTKISIGAQAGAADVTASQVHMYDFFDGAGTESFFGGDYPVQHVDTMNTYD
NSSGSTTTEETSVEPYHWRLVGKSFMKQSVEAKDEKDYTLPLHNGSEWKSSEANTDGLLG
GFSFGSDAQQFLSYAETQYSGSVAGGPANYFPNASSSDNKISNVQLLEHPFSSADLFSEL
SSSYYNIEREDARNQHSIVKPHPWEGPLRANQRCLSEGQSDVDDNNDLCILENMSEPASL
QTFSARKKPVTLMPAAFTPQCSKTMTPFHQMGPSGTKSKASDERLIFQSLVQDLSQPKSE
ASPPDGVLAVPLLRHQRIALSWMVQKETSSLHCSGGILADDQGLGKTVSTIALILTEKST
SAKTSKGKDSAELETLDLDEEDDKQMVNKIQSVKGRPSGGTLIVCPTSVIRQWDAELRSK
VSSDVGLSVYVYHGNNRTKDPYELAKHDVVLTTYSIVSMEVPKQPVVLKIGSDGRQIEVE
DSSVKSNKKRKHSSTSDNRPSKKGMDSQSIKPVALPLARVGWFRVVLDEAQSIKNFRTRV
AQACWGLRAKRRWCLSGTPIQNAVDDLYSYFRFLKYDPYSVYNSFCSMVKIPISKTPSKG
YPKLQAVLKNIMLRRTKGTLLDGKPIINLPPKTVTLKKVEFSEEERDFYSRLEADSRAQF
QAYADSGTVKQNYVNILLMLLRLRQACDHPFLVEGGSSSIVKSSIRTAKSLPREKQIFLL
SCLEGSLAICGVCRDPPEDAVVCICGHVFCNQCISLRLNGDENQCPSTNCKSELKSSHVF
SKGTLNSCLSDLVNQDSSHVAFAAGSSDQSEFIDSQPPVRFESSKIKAALEVLRALSKPH
VSVPDDVTVLPVASDINLLDKSDAAPCATDNEHSNVSDGLSRENVVVKEKAIVFSQWTRM
LDLLEDCLKESSIQYRRLDGTMSVSARDKAVQDFNTLPEISVMIMSLKAASLGLNMVAAC
HVVLLDLWWNPTTEDQAIDRAHRIGQTRPVTVVRLTVKDTVEDRILALQQKKRELVASAF
GEDEKDSRQSRLTVEDLTYLFMA
>Sgl50583 E3_adaptor/Cullin_RING/SCF/F-box 17.2 0.0
MNNPPLPQRRIPPTTISDIDDDLLQNILSKLPAKSFASAACVSRNWNQISSRILLHPNFI
SSFSLNVSLSEAVNEVVGKVLSKPTKPHFAILSIYSEFDLDEAHALVVGKLSSRIPIVTC
DCGGIIGRNAQTDEFAEVKFGYSDTSLPAFTAGISLTVGYLPGLKVDAVPLLDTSQGASI
DKFLMKLRDFSASVSGLTSPEAIIMFGDSKADVQPLVEKMDCTLSQQTVIAGNERCCFRH
SSIDNTENVLTNRGKKPNDDAVALVFARDRTKLDGVGKIEFHFAVGAGVSTVGPCYKVVS
AKMRKLEFTTWLTAKREGENEILDGEEMLNDFELEMGEPASMYDLYIGVRKRRKYSIGSK
QVKSVTSVAYHHVIEGDEQDLYVEGWDIKTGDAFYFHVPDLSFALNSCASVSENIGKLKH
KEMIGGFVFACCGRGETFFEKPNVDSSPILDNFPEIPVAGMFCGGEIGRGSPDLGQSDDK
GQEEASRDSLLHVYSSVYLLMSYNPPTCRP
>Sgl50601 E3_activity/RING/RING 32.7 10.9
MYVASMRKSFKDSLKVLEADIQHANTLASEFPREYDGACLQMRMSYAPAAHFLLFLVQWT
DCNLAGALGLLRILIYKVYVDGTTTMSTHERKASIREFYAVIYPSLLQLQSGVTDNEDKK
QKAACTERYRKRDEEEYRQYTDLDVEREDECGICMENYSKIVLPNCNHVMCLKCYREWRS
RSQSCPFCRDSLKRVNSGDLWVFTDSRDVIDMLTLTKENLRRLFMYIEKLPLIVPESLFD
AYDSHLK
>Sgl50629 E2/UBC 95.5 0.0
MEPFGDSDVESFSETSSDYQDDIFSMYSGHAQSILSSLEDSIEKIDDFLSFERGFMHGDI
VRSTGNSTGQMGKIVDLKTYVDLESVFGEVVKDVESGKLSRMRSIFVGDYVIHGPWLGRV
EKVVENVCIIFDDGTNCEIMATDQAQLLPLSPNLLDDSLYPYHPGQRVRVCHRTGSTSAG
WLCAMSKKNQDEGTVFSVEVGLAYVDWISSAMVGVSMTLPPPCRLQDPKSLTMLSCFSHA
NWQLGDWCILPSENRLQKSLNTNIDDIFSILKKKIKFDVMWQDGSISLGLDSHSLLPVSV
LNGHDFFPEQFVLEKTSSDDLVSPVSRRWGVVRCVDANERTVKVKWESFGGVTEDTDEGN
MEETVSAYELVEHPDFSFNIGDIVFLSDNNYFVDQLNKMRIEDRTVLGSEGRAVDLSETQ
KRCFLSCIGYVFGFRNGNVEVKWASGVTTKVAPCKILRMEKDDGSVATHILPEQNVTEYN
DGMPDYESQSVHHQDSSDNSSNAAADSQSSHRSSHFFSLSQAAMGFFTSIAGNFFKQNGS
TTLPQHMSCTHAIDESNIGSFDVEEDIIESCVMFPDTQVMKMTEFDAYGSISLKPKVNDN
EENTELLSVVKPKGLKQFKQFDIVGDCSDHHFANAEGKGAALSQMKKGWLKKVQQEWSIL
EKDLPETISIRIYEERMDLLRAAIVGAPGTPYHDGLFFFDIMLPPDYPHVPPLVHYHSGG
LRLNPNLYESGKVCLSLLNTWTGTGSEVWNPGSSTILQVLLSLQALVLNEKPYFNEAGYD
QQIGRAEGENNSVSYNENAYLGTCKCMLYLLRKQPKHFEALVEEHFGKRSQHILSACKAY
MEGVPLGFGSKAENEKGNSMGFKIMLAKLFPKLVQAFSEKGIDCTQFTEPGK
>Sgl50646 E3_adaptor/Cullin_RING/DCX/DWD 93.8 9.2
MGSNNEWDAEEIFQKYLHDYLVKNNMHKTAEVFAKEANADVCAVAIDSPQGFLAEWWSIF
HDVYFHLHPRPAETGQKESPKGKQVTGTSSQGPCVEEPKYGITPQSSAHDCDSILAQKSS
KIREGANQKRMAKKFDSSSQTSTETPSRSKLAGCPSNSQRNPRKPAQQRQDKKRVATLGS
TPMGLSTYAEPKTIGLESKLTSAPLKGWPLIGGNQVPPRLGNQVLDSYLQSANTQQLVDL
SMSQTQQEIYAQFLANTPSKTLSSFPLTSDLDILFRNGIDRLSGQDGQDESIEMFFTQYE
DQADCANAPSTLQHPSNEKNGHTGVSLVEIGSLHASKGKVFSCNFSPNGNFLACAGLDKK
VLLWNMNTMSYTSSLESHAHLITDIRFHPSSKFFATSSFDKTVQVWDASEPRKSLFTLSG
HDDHVMSLDFHPRNMELLCSSDSNNEFRLWDVKGYTCLRVSKGATRQVRFQTQLGRLLAA
ASGNVVNIFNVETGNFEFSLKGHQGEVRSICWDVTGTYIASVSEESVRLWSILSSARCIH
ELNSTGHNFQSCAFHPEHHLLLIIGSYQLLGLWDPTHSSTIDTIQAHNGQIASLSSSPSA
GLIASASHDQCVKLWR
>Sgl50665 E3_activity/RING/RING 25.3 8.2
MPAQKWSQNEDPPQNDAGNHDEQLEEDDDAVVDADVEEEDKVEVEDGEEEEVDDDDDDDD
EHSDGDGGGDDDNEEEDEDEGEGEEEEEEEEEDDDEHGDGEAVDRSSSHSSDIEDDEEEF
IVIRLSDIRKEVQCPICLGIIRKTRTVMECLHRFCRECIDKSMRMGNNECPACRTHCASR
RSLRDDSNYDALISAIYPDVDLYEEEELAFQEDEKARNKQIQSAIAQTVQRQTEALSRKR
RRSQGNHRRRRNYRSEDEDDVNGHDGGKDSSSADERGTEPKPKRPKRWRGQPLPAAASGD
GAGNEKDQEVQREAGVSPAAFVGTSEMLVWGKGGIRSNTRYGSGSGGNGKHSRSRLARLS
EHLRNSDKNDDELDINVVLVSLDKEKEPLLQHPYLCGRPALSVGQLCQFIAIETSLPPEK
VEILGVKGLCATLSTLQAKTSSSTAFDACKDELQVLDAKETLAELKAACNFARGQLMLAY
RLKLT
>Sgl50666 E3_activity/RING/RING 17.4 9.0
MMLVQFHLQERSDEDHFQIDIVDHINEEDGDVEIVEEDGDVEIVEEDGDVEIVEEDGDVE
IVEEDGDVEIVEEDDDVEILEEDDDIVIEDENVDKEVVTPENDKVTIQSFLNKCDNVNEE
GYIMVKVSDIRKEVECPICLGIIRNTRVFKKCIHRFCQECIDKSMRLGNNECPKCREHCA
SRRSLRNDPDYEAVISAIFPDIDQYEEKELAFQEDDKARNKQTQATIAQANRRQKTRDKK
QRRSKKKNHGRRNYQSSFEDEDDVYGHGDGGKKCKAETSLAPAIVDEANDTNMLENSLTR
VSTEFFGTTSNSPLLVWGKGGIRSSIARHGSCNNGNNNHPQSRLSRLAEHLQKSNINEDE
FISSRTFVPPDKVEIWGVRSISSKLSSLSTVELQSLKSIAVDASKDELQILDAKETLDGL
KATSDFARGQLVLSYRLKLE
>Sgl50856 E3_adaptor/Cullin_RING/SCF/F-box 29.8 0.0
MDHVETNCKLPEDLFRDILSRLSVRDLLRFRSVSKSWCALIDDPSFILTHHFIQYAMHKA
NGDVPLLLWRHIGSIRGYQTECYLFFKQQGYDTISNWTSDVERYAHSVSPSDPNINLGIF
CRGSANGIICLDFQGTDLKVTGRDFYYISLWNPAIRDFKIVAYPHVADQRMPGNFVVVGF
GYDPVTNDYKIVATTVVSSDIVLVYMVYTLSTNSWKRVNEPSLFGSNASVRSSLMDSCLN
GVYYWTAHLLNNIEDKIFRILSFNFSTEAFIFSDPPQEALPHVYLMGNEFYWNIGLYNER
LALFLIHPALDTPESSADIWVATEFDDEFGVPVAWQCLISIKPIFERIGSTFGAQWVDGD
IVFQLFPNEFCLYNPTTGKFRRLGISFRHCFSYVMDHVETNCKLPDDLFRDILSRLSVRD
LLRFRSVSKSWCALIDDPSFIRTHHFIQYAMHKANGDVPLLLWRHTGSIRGYQIECYLFF
KQQGYDTISNWTSDVERYAQSVFPTNSDINLSIFCRGSANGIICLDFQGIDLKVKRRDFY
YISLWNPATRDFKIVVYPHVADQRMPGQFVVVGFGYDPVTNDYKIVATTVVSSDIVLAYM
VYTLSTSSWKRVSEPSLFGKTASVRCSLMDSCLNGVYYWTAHLLNNTEDKIFRILSFNFS
TEAFIFSDPPQEALPPVYLMGNEFYWNIGLYNERLALFLIHPALDTPEASADIWVATEFD
DEFGVPVAWQCLISIKPIFERIGSTFGAQWVDGDIVFELYPDEFSLYNPTTGKFRRLGIS
FRQCFSYVESLFPLSR
>Sgl50863 E3_adaptor/Cullin_RING/SCF/F-box 14.9 0.0
MDHVETNCKLPDDLFRDILSRLSVRDLLRFRSVSKSWCAVIDDPSFILTHHFIQYAMHKA
NGDVPLLLWRHIGSIRGYQTECYLFFKQQGYDTISNWTSDVERYAHSVSPSDPNINLSIF
CRGSANGIICLDFQGTDLKVTGRDFYYISLWNPATRDFKIVAYPHVADQRMPGQFVVVGF
GYDPVTNDYKIVATTVVSSDIVLVYMVYTLSTNSWKRVNEPSLFGSNASVRSSLMDSCLN
GVYYWTAHLLNNTEDKIFRILSFNFSTEAFIFSDPPQEALPPVYLMGNEFYWNIGLYNER
LALFLIHPALDTPEASADIWVATEFDDEFGVPVAWQCLISIKPIFERIGSTFGAQWVDGD
IVFQLYPDEFSLYNPTTGKFRRLGISFRPCFSYVESLFPLSRRVA
>Sgl51026 E3_activity/RING/RING 32.4 4.5
MDVCWLSFASSFSQLKFVLFEKVVQLLQCMQNRAFGFQFALKLLKYVALAIGTIIFAFGG
VIVGGIAGAIKGQTTESGLCRGASIGFLSGAIVALELLDSLLNGHFHTKVALFGSIFDGK
AFREWVSPAVLKAYQWQQTSMNEGLDNEEGSDIYNIVEIRGMCPEQIKKLPVINFCCTSS
NSSSLPISHNEVCCTICLQDLVEGEKARKLPGCEHLFHMMCIDEWLARSTSCPVCRNNVD
LSDYLGCENVL
>Sgl51036 E3_adaptor/Cullin_RING/SCF/F-box 15 0.1
MATLFPQEIEEEILLRMPAKSLHRMKCVCKTWNSIICSPSFISSFNRRNSHNPKLLLLKH
PHPRRLPPNSATNIHFSVSSDSFVELHSIKVPQQINNGDDDLRPIRVELVTSNSINGILC
VLVYMGLSNGKLMNCEMFLWNPSTRETMTIPSSEFSGLFSGVPMVKFCCGFGVGFNRDDY
RVVRVSYLNTIKPTTEVYSLRNDRWMDLSLLPRSGISSNILWASSTCTFVDGAGYWGAFS
SESKDEFFVLGFYFACSYFRKVNVPEECVDGRDLRYHSLWVYKGMLAISVLRFAEFESDI
TRHYIWVMKPGRTLGSPNWCNMFNIDLVGGPRKPVLTLGNGEVLLLGEDDGEHALYDPVT
EEVKRVDISDVDTVISYTESLVSLSKLMPQDGVAVSYG
>Sgl51038 ULD/UBL/ATG8 160.2 0.4
MAISSFKFEHPLEKRQAEAARIREKYPDRIPVIVEKAEKSDIPDIDKKKYLVPAELTVGQ
FVYVVRKRVNLSPEKAIFVFVKNILPPTAAIMSTIYEENKEEDGFLYMTYSGENVFGLKG
LH
>Sgl51076 E3_adaptor/Cullin_RING/SCF/F-box 14.1 0.1
MAVSTMDVDRISSLPLELKAEILSRIPSKSIFHMRCVSKNWESEIKNQVFIHLYVQCQLG
LNFGWCFEESPTMVMLLGDDSLYSYDFETDVQYRHRHSPPNLGGSLKAQLIGSCHGLLCF
QESCCRFSLYNSATRSYATLPTLGHEEFIKCTTKRDAGFGYDFTSNDYKVLAFDTIIPTN
NDLEAYYLTHIYSLKSNSWRKIKNMPRGDSMVYLKNALHWVTTSYREEEEDQIPVIIAFN
LGIEDYYELQLPSTAGNSTPSVYDSNLTALNGCLHMGDYTPWDMNMTIWVMKKYGVAKSW
TKLVQSTIFDNEPWRLRPLPYTYLKSETQILVGLEAYPERFVICDIQSQELETMLRIQVP
TEELHAEESDDEDGEGDGEVDGGFFVVPLPTSLACVDPLLPIIVRTKYFSMQNIKMTLLL
GDSIRVLELKKELRLLMKAITDEEDNQIHTNNYHNNNDFVSNLSSSSFFDTIDKVKDLSA
LQDVKLKRMTSLRLYDDTLSCPLSKQLMKDPVIIISTGQVHPHHSKKSNNLTRITWSGEV
EAK
>Sgl51113 E3_activity/RING/RING 31.1 10.1
MGLGGDQSSSVSVSSSSCSCSSSSDSSGPIRVLLYFHKAFRGELELLLRLASDSDQTYTH
RAAQLDKRLHFFRTVFTYHCAAEDEVIFMALDARVKNIATTYSLEHHMIESIFGSIFSCL
NSIMNKEEHEQDDHPFQQLTLHITTLQASISQHMTKEEQQVFPLLMTHFSDKEQGFLLWQ
FVCSVPVVLMEDLFLWISSFLPPQQHLDLKHTITTILPHHTLLQQVVISWIDNTTQPHCL
NYQLDFFKHISTPSFSFSFPIIDQPHFHSDTPFHALFLWHTALRSDFKQILDNLSKIGSN
NFSTLPSLLVRINFLTDVLIFYSGALETIFYPLLQGASIFQTLPSYKAFPFKYEIEGFQK
IIFDVTQVNFANPTFFKMLCRKMEDLMLATTSHLSFQETKVFPLIINNYDHETQQKLLFR
SLCMLPLGLLKCVATWFSSHLPRDKLNCILLGVKHSSFLARPFASLLHQWIRIGYSGKFT
MEDLQEMFNSRLSYLFKQFREGKDLSNNLEHAMTKHTSLDSSSFFSHSLSRCFQQTEKHG
TLYSSGINLLVFSSRTSNQVHTIFGSPVEAVSANHREPRPMDHIYYFHKAIKKDLESLVL
DSTKLSKNLDLFVDFNRHFRLVRSLYELHSETEDQVAFPALEAKQKVQNVTKSYSIDHKL
EDGCFSRVAGILDQMSELYGTLSGSGVDEVGPASLKYHHLCVKLQESCKLLEKILNDHIH
REEIELWPLFRENFSTEEQEKIVGYMLGRTRAEILQKMIVWLMASLTSEEQQAMMDCWRK
VTKCTKFDEWLGDWWEGMESNVFSEVEKPDFSSSSTMGSLNTIVKHFSTGVSHNRGKNFK
VGRMKFPDDEARTINMVKTMEGLGKDNKKQKSFEYKMLLGEKEKHKKEGTLTDSVSELEA
AIRKVSQDSSLDLQAKTRIMQDLMTSHCVVQSLPDSNRVITSESGKLPGQFPSYRDTEGS
ILGCKHYQQNCKLVAACCSQIFTCRRCHDEVSDHLMDRKSTTQMMCMLCLEIQPIGPTCL
TPSCNKYSMARYYCKICRLFDDNREIYHCPYCNLCRLGKGLGIDYFHCMKCNACMSRSLS
STHICREKCIEDKCPICHEDMFTSSDPVKALACGHLMHSSCFEEYTCMRYTCPVCSKSLG
DMQVLFGMLDALLAEEKIPEEHIGQTQAILCNDCEKKGIAPFHRLYHKCPFCGSYNTRLL
>Sgl51124 DUB/USP 79.3 0.3
MNNTSQRKPSSPPLSQSMELELADSSMIKQECEKALNALRRGNHNKALRLMKESSNKFEN
SALFHRVHGTIAVKVAGIIDDPNAKHRHFRNAVESARRAALLSPSSIEFAHFYANLMFDT
ANDGKDYEEVVSECERALAIENPIDPLKDNLNNQQLEEESAEVRIAQLQGELRGLIQKSN
IASISTWMKNLGGPPGEEKFRLIPLRRLSEDPLDSRYFSTTNSNARRPNEIKKATKTPEE
RRKEIEVRVAAARLLQQKSEQGQIAEEGRNGTGTHSATLVSGSGASKAAERRRNGSSRRI
ISFCERKDQVRSFWNSMSSEMKKGLLRVSVSDLMAHFSGLSNKDGGQAFEVLSEALEFGK
MNKSWKFWVCCHCGVMFSNADAHVQHVVQEHMGNLLSKVQSAVPHSVDNEWVEMFVSCPW
KPLDLTASVRMFEDLPKHEGSQYPGQENHTEKIGEFWIESLCSEEWGRFPKKKILSDGFN
GSFSEGEGGGNDSKFECKTYDSKKDSKLYSLPKNWPLLDDIEREKLLEKINSLFQMLIRH
KCLAITHLQKEVSHACGLGRYPGKVTQDDAVNHSLGSDCHERIVLNEDASSLLLDESLLN
SDGMSSDMGSKYSLSTSEKGVQYVSDSFLSWIYAGFSSDEQLATWCKLREERSQQGMELL
QMLEKEFCHLQSICDRKFELLGYEEALQGLEDLCLEESKKREHITEFAHCSYDSILRKRR
DELAEGENEDLFSSNRLELEAISSVLKEAENLNINQFGYEETYGGVNSHLCDLEAGEDDW
KSKDYLHQVDTCIEIAIQRQKEQMSVELSKIDARILRNVGSMQQLELKLEPASALDYRSI
LLPFMKSFMRARLEDLVEKDATEKSDAAREAFLAELALDSKKGSGNGNDNSRQMQDKMKD
RKKNKDAKRNKYLKAGSFNEHPEPSEQFSLAATSGCDYVHTDSVASTSRDDLKALEEEFQ
RKNELEAEERKLEETLEYQRQLENEAKQKLLVEQHQRKAVATSHGVEKYLHDVPLDPNFL
LAVQCEREQLVSKFCVEDLDGVNRNVVDGGVCADIADGVLDREIFSGTDSSEHRTFTKGK
RRSSTKLLEGRLQASHGKEIGNSCADMLQKDQVWNRDSGRSCSGNSDAGSKTLRQLQAEE
DEEERFQADLKKAVRQSLDTFQSGLKQSMVQNSSVAQQRSQLVDALEFSTGERIRLNGSG
MDTFGAGLLNDIGEYNCFLNVIIQSLWHLRKFRVEFLKRSPTEHAHVGDPCVVCSLHNIL
TALSVASGDSSSEPVAPATLRIALSNLYPESNFFQQGQMNDASEVLAVIFECLHLSFTSV
SGGSDCESVESNSLGSWDCSSPSCIAHTLFGMDIFERMNCYNCGLESRHLKYTSFFHNIN
ASALRTMKVMCAETSFDELLNLVEMNHQLACDLEVGGCGKLNHIHHILSNPPHIFTTVLG
WQNTCESVHDITATLAALATEIDISMLYRGLDPKNVHRLVSMVCYYGQHYHCFAYSLDHE
RWIMYDDKTVKVIGTWEEVVCMCERGHLQPQVLFYEAAN
>Sgl51142 E3_adaptor/Cullin_RING/SCF/F-box 12.4 0.0
MAGAAIPLDILHNAILPRLPAKSLLRFKCVSKQWLALISTHQFIKLHLSYAITNHLLILT
ANHNCFYSFNLDFPSDPALKLPTFGIDSVVVGTCNGLLCIQSFRPYRLSLLNPSTRTYRE
IPSLLPPRRCSALNFGFGYDSTNDDYKLVRIADRYPSLGFLTHQLDRIVHVYSLSTNSWE
FIELTSPHSSMGVRENGALLNNILLHWKFWCYQQGKYRIRCFHLCEKQWTHDVPLPEFLD
MNSSSQSNTSTKDALLDFGVLDGCLYLSTKNQQQSAIDIWLMNDYGVKESWTKLCQISDS
RVFRSLRVSPIAYTSLKHQILLRTVDKTEHKILWYDIKGESAETFEINGVADCIWIVASK
DSLASVPGGFQIGTNKEKDETELLLVDALM
>Sgl51260 E3_activity/RING/RING 38.4 4.0
MGDIDFTIYIPDWSSSESNNTLIGIAACLVVALCVYIVVKVKKLYQALFGSPAVSNGHDD
RDNNNNSTELKEVVVVVDEETVKEVSKNCSECAICLEKLGVEYEKYGREKGELVLKQCGH
KFHEPCMLTWFSHGNLTCPTCRRPCYAI
>Sgl51287 E3_activity/RING/RING 21.7 11.3
MGKSHQKKQNFSQRRQRTSENRKEKLLHDCNDHHLGDDTKKIQTCSSSNFQPSYQPKFKW
VSRNSGAHVENSGSGPKLEVGQSSSDNGPKPEVCQSSCEVGESSFDERESEVRERKCGDE
EEKVEEGFELNEEGGGVDDVVRRLEELQLGVEEVELSEEQINNNDQAQEDELLAMESIYG
DSVYVIEKRQGLRSFQIHIHIELPSAYTVSAKFNADTHDESTSSNSDEFLYNFKVQYLSP
IILTCLLPRSYPSHSPPSFIVSVQWLHESKISKLCSMLDMLWNEQPGLEILYQWVDWLHS
SALRYLGFEEELLLGPYSMRSISDRRALSGSISADVDIPSMKSYNEERQHENFLNGCHEC
CICFSEYAGTEFLRLPCHHFFCTKCMKTYADVHVKEGTVKKLQCPTTKCGGMIPPGLLKR
LLGEEDFERWESLMLQKTLDSMSDVAYCPRCETACLEDEEQHALCSKCFFSFCTLCRDRR
HVGIACMTPEMKLQFLQERQKIFRTIKDGQRHMELEKFNELLSLTEIRRDAKQCPSCKVA
ISKTGGCNKMVCSNCGQYFCYRCGKAISGYEHFNEKGCELFPQEMIQHWEQRMNNRQAIG
QIQANLYAANVQPCPNCRQVNAKVGNNNHIFCWACQNHFCYLCRKNVRRCSEHYGPRGCK
QHTVG
>Sgl51300 E3_activity/RING/RING 30.4 13.3
MSSIESPPIPEPPYPQDPTPPVTLVLTILLLVMFFVGFFSIYFCRCFLENIVNSLNNRQT
PNGTPINPSSLTPPGLDNKIVSSFPTFSYSTVKDYRREKYGLECAICLCEFDDSDMLRLL
TTCCHVFHKDCIDLWFESHRSCPVCRRNLDALEIRQSSERIPNVIESTRNSIGNNIVVDP
EIADGNNNNNNNNSNSMDNDAIIVIKEDSYEEPIDEAASSSSKGNIQDLYSNEKFSRSHS
TGHSIIRNNPKEDDDKYTLRIPEHIRRHLALSWANLGEYSNNSTSKHECFGEISGTATQG
DTNKVLV
>Sgl51303 E3_activity/RING/RING 29.8 7.7
MNTKDCSLKLCSTFCPQWCDGIFLPPSPPPPPPFTFPDDKSETSPTFSPLVIAIIGILAS
AFLLVSYYAIITKYCGKSNSSSRRSREIRRSNNEELFEDGNDDGGNTTNNTQQQHHEAWL
INTPGLDEALINKITLVSFKKGDGLIGSSDCSVCLGEFHEDDTLRLLPKCSHAFHVACID
TWLRSHLNCPLCRANIISTYSQPPPSNHNNPHIVVDNSNNNNNDNNNNNNVIQDHSTMVE
NQVAANEEISSSGEGRQQLEVIVEQGNGNIPKTTPFRALSDLGVRGHGGRDTMRRSISMD
HRHETRVSIPDVYVCSHGEDCIVQICRIDEQPLKITVGESSKVSVSSSSNTSAVLHCVKN
SVAMKRSFSGGKFLFSKHVKGKNAVNPL
>Sgl51315 DUB/USP 287.4 2.3
MDLEEETRKFKTLDPLQSIETEIPVVGEITVSKSMENDKPLSDVGVSDRIPGDSSGTQSN
VISSEEVNPILEITEIENQSSDFVQFNETLIGSSLIDESQCSKPLVELENGKKFDDIESS
KAETLDESVKEGDKKLEDSQIKKIIDDSVDEEGEDEELTKTLTELSAVAIEGDEIGKFNC
TDLLNDLENRNGFGDNSESGIGEEELSLVPGPWSEGHRNQCDCAHCLEAEQEEWSWRNNG
LGWPSSSSRMFQPKRHCRRRGFNFRREKEAEMYDYMGGYNARLNCLNIGYYEPEPCPVGA
GLANLGNTCFLNAIMQCFTHTVPLVEGLLSLKHKASSHGADEFCVLCAVCDQIEYSLVNS
GRVISPSNLVDNLSHISSYFRRYQQEDAHEFLQCLLDKLDYNWSKYETSDNDSLWSDDTL
VKQIFGGRLVSQIRCCSCGHHSDTYEPLIDLSLEIEDTDSIEGALKSFTKVESIEVTENF
LCDNCKEKVKVEKQLILDQAPSVVGLHLKRFKSDGIYVEKIDKKVEFPLELDLGPYTKGS
NDGHEDLKYELFAVVVHVGFSSTSGHYFCYIRTSPEKWYRFDDSKVTMVEEETVLDQHAY
ILFYVRKGTPWFDSLIENWKAECHKKILSTSPKSVLVDTDLQSSSFPARTSFLGGDGINT
GDSGFEVQNKPGVGIGLHSCEAAEMRDATWDASVAPTTELEQDEVEVKAGLDAWDAAGAN
QAYVSSSSVPKRNSLEDKGDGVKEIDANEDQNCKEIGKIEQISCGGTCSPSLVKNTFDGE
PQNEASISPSTPPRALSPDIYSDTEPTGEAYCIPTSHLKIKDKPSSAKKSVNTLKQDMKR
KEAAKYIRRSMPGGRGHMFMAAMSGSKSDSIMSKKRRKHASLHGRQSPKKRVKVSPKRVL
RPVTA
>Sgl51333 DUB/USP 354 0.1
MDDTFDLDDFPTVESSTFNFDNDDDDDILFSNTDLRRRRRRISPSSSLRYDRVFLVCYKW
WNEASKSECLGEEKGVFYAAASPSSDDDGGGSKEEECGTCTDDEIVLNFRREGDDEDDKD
KGEGFSGREYALISESMWFKALKWHSDYWTRIKDVGCSLTAENGNQDVFPIHLRLFVMWQ
TNLLAVKISLMDNPVELYKRAYQIFNVQFDSVCIRDFSGQMTRFLEGDAALPPRLQVLLE
LQVYGLPKHGKDTQSRKLEIAMQGRSNSGGPCSSYSTKMNGIAENHNSYLPFLSSYSCTQ
GYRETGVLGLTGLLNLGNTCFMNSAIQCLAHTSKLVDFFLGDYKKEINYENPLGMNGELA
LAFGDLLRKLWAPSGMPIAPRLFKSTLESFAPQFCGYNQHDSQELLAFLLDGLHEDLNRV
KNKPYVQLGNTEGCPDDDVAKEFWQCYLARNDSIIVDLFHGQFQSTLVCPICKKASVTFD
PFMYLSLPLPSATMRTMTVTLLSSNNEHMLSSPLTVTVPKYGSCKDLIQALSMASTLRDD
ETLFVAEVYNHRILRSLEDLCDSLALIRDDDCLVAYQIPKEKESSLLVIFMHQRSERHPG
FRMTRPCWSLFGIPLVARISSLSRGSQIHEEYMKLLRPFLNTVENDNTEKSDKDLAKIES
RSSSNSDNSWSSDDEMVAQLHGASDFQFHFTDERGMVMGQRIKLGEPLDVSGETKKINVL
VNWSEKMWRLYEISHLNLLPEVFRSGFFASKPQESVSLYKCLEGFLKEEPLGPEDMWFCP
SCKEHRQASKKLDLWRLPEILVVHLKRFSYSRFLNNKLDTYVDFPMDQLDLTGFLARESD
QSANCYRLYAISNHYGSMGGGHYTALAYHGKRWYEFNDNVVESVDEEEIKTSAAYVLFYR
RISDT
>Sgl51350 E3_adaptor/Cullin_RING/SCF/F-box 15 0.6
MVTGESKPPSVASAGALFDTEYQRSYVFLFVIHSSELLEKALLLQSLEELVGRNNVTIFA
PKNEALERDLNPEFKRFLLEPRNLKSLQTLILHHIVPSRVDLTNIVKPTRKRAMSNHHLH
LSSTNNKILVEDSVEVVDRNSIVRPDGLIHGVNKILIPQSILQDFNQRRELRSISAVLPT
AAPTVDPRKTKRTPRSKMGPAGSPQAGPAVSIYEALAPGPSLAPAPAPGPGGPHHHFDGA
SQVQDFITTLVHYGGYNELADILVNLTSLATEMGRLVSEGYVITVLAPNDEAMAKLTADQ
LAEPGAPEEIMYYHIIPEYQTEESMYGSVRRFGKVRYETLRLPHKVMAEEADGSVRFGSG
DGSAYLFDPDIYTDGRISVQGIDGVLFPTEEAKSPSGVKKVVAKQRRGKLLEVACTLAAA
FGQDSQFTSCSPRI
>Sgl51352 E3_activity/RING/RING 28.2 13.9
MDLARESDDQVTDLAAIVEGGVHGESDDACSICLEDFSQCDPSTITDCKHQFHLQCILEW
CRRSANCPMCWQPVSLNDATSQDLLEDIERERTPKANRSRNPQAFYHPTVTNVDLHLPAD
GSEIDLEEHIFQHLAVAASRQSRHHVSRREGQQPGFLFTRTPSIFNFLNSHNPS
>Sgl51396 E3_activity/RING/RING 21.4 10.0
MGCTVREKHIRTGRRSRLTKPTNTNTNTDVDHNHNHNHNHQSGINDRTSALAKSMLESGF
KPWTHNMGFNDSMQNSGSNPNNPNSSSTQNFGFDDSGWGYCTEEQLEEILLKQLEFLYNQ
AVSKLVSLGYDEEVVLKAVLRSGHCYGGMDVLTNIVHNSLTYLSSGCCGNDEEFEESELV
FMDLRQLEEYSLAGMVCLLQQVRPQLSRGDAMWCLLMSDLHVGRASTIEIPVAPSPSNVC
GNALSSVGSFSTNPSSSGISVPPGLCKFHGGWGFGNEASSELPVNGLGGFFPYSEASFQR
EIDCAKRFNLSPSMKSLLKRNVAAFAAGFRSKQQLQLQSQRCTTSAASGGSSKGTAPVVD
VPSVPSAESKDSNQDIVNSLLSKFRDLNLDENLDCVTEDQKDEIMLTLLHQVKDLEKQVT
ERKDWAHQKAMQAARKLSSDLTELKTLRAEREETQRLKKGKQTLEDTTMKRLSEMENALR
KASSQVDRANASVKRLEVENAEIRAEMEASKLSASESVTTCLEVAKREKKCLKRLLAWEK
QKTKLQEEISAEKQKIADLRRQMLQILASQKEAEAKWKREMKEKELAMTQVEEERRSKEA
TESNNKRKLEALRLRVEIDFQRNKDDLQRLEQELSRLKANAQPLEPHDSSDAFAKGSPEA
ATNQGESIERLLQDLDEPEKEGSERECLICMKEEVSVVFLPCAHQIMCASCGEDYGKQGR
ATCPCCRCPIEQRIRVFGASS
>Sgl51403 E3_adaptor/Cullin_RING/SCF/F-box 20 1.4
MDSNDENLVETKTLIEFDQSTSSSVVKEESHKLDLTNSTAMGGRISKSQENGSGVLEDEN
FHRNSANGGSDGGGGKDVMVGKKEASVADDVEVGKGVKEIKNDEKLDGIPIRSNGSGDGV
KEVCGKSGPVAEFQDERSSSDTKLNDDVSGSIAQRTRNRVVTGKKEDIDEDDVRMGNTSD
DDVDEEHGFSVGDFVWGKVKSHPWWPGRIYDPSDASEFALKYKHEGRLLVGYFGDRTFAW
CDPSQLKSFEENFEEMSKQSSLKTFVNAVQEAENEFGTLVKIQMTRSYARESQSSLPLVV
NAGVKEGVHIPETGIGFFTVAQFKPLAMLADIRRFAIFDSVANTLELTVLKSRLVAFNHA
KFGYSLPIHCEPIGIEDLTDNQGALLGPLFPGPDDGGMFVGPEDQPVGQNEPMTPVGMSH
STRKVKSIAELLERETKDKLKGHDLEKTKGETQSGKLVSTSRKKRWNVSDEDQSTVNEVK
GDDGSSKDEEQQPVRKSGRKKKMAVDENQSNEVGDVVVTRSSSRKNKQSSARSTSSEKKA
SASDGTEDGGKVKDQRKMETMPQVSVNSGSAVEEGYERISPREKKLSKYLCPPYTNILQR
QRSSCSQTSSEAGHVFSDVAKVGERMAKTPGKLTGSPPLVKCSAETFRKSSKVSGPMRKK
IDHPNQNTSKEDPSLEVKGPVKSINSVNSVLLDLRSAALDPLYSRRGQSFDSINGFISSY
RSSNYIDGSNYASYKKALADVRKRQRKRKRNVSDNEHLLGQKLLDAVDQQTPKSEPLEAK
STRKRKQKSESKAGREVGPSPSATLVITFPASFPLPTQKDIINMCSKMGGVDKSKTEVVP
ESSTVKIVFVQSSAAEAAMDSMQKSMPFGSVGVSYNIEHLATGSSDRKQLKVNVQNKKKM
KSSETSEATVANSLGKQLSVSPAPAPAPAPAPAPAPESDPLAIVFIKQKLEAMTSMLSQA
DGKMTQEIKANLENEAKELLKKVKKMTASPSE
>Sgl51457 E3_activity/RING/RING 34.5 6.5
MRTVNNTSLSTSNAGPTPTTPDFSGQDESVGGFTYGLGVSIGILVLITTITLASFFCTRD
EANQSEGQHQNHHHQGGENDHTVITIEGIDEKTLNTYPKWLYSQLKLTKNNDNDNKKGST
VMSCCSICLADYKGNDVIRELPDCGHVFHLQCVDPWLKSHPTCPVCRTSPLPTPQSTPLA
QVGVAPLASTPNG
>Sgl51464 E3_activity/RING/U-box 105.8 0.8
MDFSEEIEIPSYFLCPISLQIMKDPVTVCTGITYDRESIEKWVFNNNNTICPVTKQPLNV
VENTTDIFLTPNHTLRRLIQSWCTLNASYGVERFPTPKAPVTKAQVQKLIDEAMTHLSPH
RVVKSLETIKSISTQSGANKRCLETTPGVPEFLARVIVLGEDEEDRLLYVNNTRVSDEAL
RILAHLQILDSEIVLRKMLNEKVGNKLVESLVRMMQRSNYESRAYAVGLLKQLVQVGDPT
HVVALKREHFVEVVSLVKDDISPKATRAALKVLALACPWGRNRIRIVESGAVPVLVGILV
ESNDKRIIETALAVLDYLSGCAEGRAEILGHGAGLAIISKKILRVSSFATEKGVKILSSI
CKFSGSPSVVQDMMQLGVVMKLCLVLQVDCEAKTKEKVREILKLHARAWRNSPCVPAHIF
GSLC
>Sgl51465 E3_activity/RING/U-box 100.9 3.4
MDFNEEIEVPSYFLCPISMDIMKDPVTVCTGITYDRESIEKWVFNNGNTSCPVTKQPLNI
VNENTTTTTMAADIFLTPNHTLRRLIQSWCTLNACYGVERFPTPKVPVSKAEVRKLIGEA
EAHSSSPQRLLKCLEMIKSISAQSSANKRCLETTPGVPEFLARVIVLGEEEDEEGRCGNK
NGSSMRMMGGSRVSDEALDILAHLRIPDNEIVLKKVLNENEGKLVESLVKVMQRSNCDSR
GYAVGLLKQLAQIGDPTHLAALKREQFVEIVKVVKDEVSPKATKAALRMLALVCPWGRNK
IRVVESGAVSVLIGLLVESNDKRIVEMVLAVLDHLSGCAEGRAEIVGHGAGLAIVSKKIL
RVSSFATQRGIKILYAVAKYSGSPSVVQEMLQLGVVMKLCLVLQMDCEDKIKEKAKEILK
LHARAWRNSPCAPAQIFGST
>Sgl51548 ULD/UBL/ATG8 161.2 0.2
MAKSSFKQEHDLDKRRAEAARIREKYPDRIPVIVEKAERSDIPNIDKKKYLVPADLTVGQ
FVYVIRKRIKLSAEKAIFIFVDNVLPPTGAIMSSLYEEKKDDDGFLYVTYSGENTFGYPS
ME
>Sgl51660 E1 578 0.0
MLPVKRPAGGEADNDEVVEVFAFNSTLKKPCLISIAAASSSSALTATANGNAQGSENGES
ENSTMGLGDGDSKKTNNNNPNDIDEDLHSRQLAVYGRETMRRLFASNVLVSGMQGLGAEI
AKNLILAGVKSVTLHDDGVVELWDLSSNFIFSEEDVGKNRAHVSVQKLQELNNAVAVSTL
TTELTKEKLSEFQAVVFTNISLDKAIEYDDYCRSHQPPIAFIKSEVCGLFGSVFCDFGPE
FTVVDVDGNDPQTGIIASISNDNPALITCVDDERLEFQDGDLVVFSEVCGMTELNDGKPR
KIKNARPYSFTLEEDTSGFNPYEKGGIVTQVKEPKVLSFKSLREALQDPGDFLLSDFSKF
DRPPLLHIAFQGLDKFISTLGRFPVAGSEEDVQKLISFVKEINDSTTDSKLDDIDQNLLR
HFAFGSKAVLSPMAAMFGGIVGQEVIKACSGKFHPLFQFFYFDSLESLPTEPLDPSDLKP
VNSRYDAQISVFGAKLQKKLEDAKVYVVGSGALGCEFLKNLALMGVSCGSQGKLTITDDD
VIEKSNLSRQFLFRDWNIGQSKSTVAAAAAAVMNPRLNIEALQNRASPETENVFDDTFWE
NLNVVINALDNVNARLYIDQRCVYFQKPLLESGTLGAKCNTQMVIPHLTENYGASRDPPE
KQAPMCTVHSFPHNIDHCLTWARSEFEGLLEKTPAEVNAFLNNPGEYASSMRKAGDAQAR
ETLERVIECIDKDRCDTFQDCITWARLKFEDYFSNRVKQLTFTFPEDAVTSTGAPFWSAP
KRFPRPLQFSTDDATHLNFVLAGAILRAETFGIPIPDQIKSPQALADAINKVIVPEFEPK
KDAKIVTDEKATSLSNASIDDAEVIEQSIARLESSRGRLSPSFRMNPVQFEKDDDTNYHM
DMIAGLANMRARNYGIPEVDKLKAKFIAGRIIPAIATATAMATGLVCLELYKAMDKGHKV
EDYRNTFANLALPLFSMAEPVPPKVIKHQDMNWTVWDRWILKDNPTLRQLLDWLQSKGLN
AYSVSYGSCLLYNSMFPRHKDRMDRKMVNLAKEVAKAELPAKRKHFDVVVACEDEEDNDV
DIPQVSIYFE
>Sgl51665 E3_adaptor/Cullin_RING/BCR/BTB 27.4 0.0
MQNNILSTMRSLKLIDGCKGTQVYAINTSSTTTTTTTPNGGDNNNNNGGGVGGTISGTGE
KLLHQLQDHLRVNSVRSKTRTNSNLDAKILQTNLLQEAVLPFGLPSTDLVEPQVETCLKF
VDFVETLADIYRRIEGCPQFEKSKFYVEQCAIFRGLSDPKLFRRSLRLARQHAVDVHTKI
VLAAWLRFERREDELIGSSPLDCCGRNTECPKASLVSGYDPESAFDDCVCRRVGNDVILD
GNGDGDGDGEDGSVAEEDDSEGFTRIEDEECSTSEEDFDMSFVVGEEEVWCIRDNIASLS
RPFETLLCGSFIESKREKINFTQNGISAEVVRALEFYSRTKSVDRFNPQLVLELLSLANR
FCCDELKSACDVYLSSLVVDKERALMLMDYGLEEAASLLVAACLQVFLRDLPGSLHDQNV
MKYFCSSDASNKLAFTGHYSFLLYYFFSQTAIEEDMKSNTTVMLLERLVDSATESWQKQL
AFHQLGCVFYERKEFKDAQNWFEAAAEAGHVYSLVGVARTKYKRGHKYTAYKLMNSLISD
YNPTGWMFQERSLYCVGKEKLSDLEKATELDPTLSFPYKYRAIALLEDSKLGAAISEVNK
VIGFKVSPDCLELRAWFSIAFEDYEGALRDIRALLTLEPNYMMFHGKMPGEQLVELLRAH
VQQWSQADCWMQLYDRWSSVDDIGSLAVVHHMLANDPGKSLLRFRQSLLLLRWIENFRIY
SSLPKGLSQLSSGVVPDLLMDDHKEEEAIAELSGAIFFKPDLQLLHLRAAFHDSMGDYAA
TLRDCEAALCLDPTHVDTLKLYSEARERVVDQQQSSFEDVDRNDALES
>Sgl51668 ULD/UDP/UBQ/UBQ_Other 40.6 0.0
MNQSEEVDEKEWEMRPGGMLVQKREDGDEDDGGPMFKIKVSYGSSFYDFTLPCKFTFGEL
KKLLAQKTALEPEDQRLFFRGREKEDAETLLKAGLKDHSKLLLMERPASKEKKLEEARKK
EEISKACAAIAGVRAEVDKLSQRVSSLEASVISGTKVDEKEFIIATELLMVQLLKLDSIE
AEGEAKTQRKNEVHRVQGYVDALDALKAKNSNPFGDCGNTVSVSTNWETFDSGVGSLTPP
SVSSTKVTEDWERYLIPYKLKSLHSDAKNLKNLIDADIVHPNQSLLPILNDVAALIRGNW
VVIINHIPRDANEVAHQLARLSLGLPDNHTVHLAMPDYVANAFRRDLENAGSSSSASAST
SVPARG
>Sgl51704 E3_adaptor/Cullin_RING/DCX/DWD 14.4 14.5
MFAKRLLQKAIHHHHQHQNQKDTQHETYKPNDLDPQILIHFGIPNTASILAVDPIQQLLA
IGTLDGRIKVIGGYNVEALLTSPKQIPYKNLEFMQNQGYVVGVLNDNDIQVWNLERRCIT
CSLQWESNITTFSVLSGSPFMFVGDEYGMVSVLKFGAEEEILVNMPYHMSPDYIHEKTGI
SLPNDQSVVGVLPQPSSFGNRLLIAYQYGLFILWDILESKVIVIKGDKDLLIKDHVSDSP
SELAADPLDNAHEHMNEKEISALCWASSVGSMFAVGYIDGDILLWNIPRGASIKRKNASV
SRDDVVKLQLSSAEKRLPVIYLCWGESSMSQSSCGGQLFVYGGCEIGSEEVITVVSLQWS
PGMEVLKGVRRVDFSLIGAFADMVSLSSLETAGKSLFDGLFVLTRPGNLKFYSTDCLSAL
ISQPERKSSVSGIEFPVIIPSSDPQMTAAILSLQPSDGNLSMWLSEMASVFSTLNPAEGK
KWPLTGGVRRKISSAEENSQNLIYIAGFQDGSVRIWNAADPIFPLVYTIEGQVHGIADVG
ANISVTKLDFCASTMNLAVGTYCGEVRVYCLNNDSGGIKLHWIKHAEHIVYDVPSQKGPQ
CRAVFTLMNSPVQSLQFSVSGAKLAVGFESSHVAVFDMIALSVLFSTDPVANSNSQVISV
NLNTFSDAQGSTTGPKHSESKNVELAGEELLFTLTRDAKVNVVNSKTGSPISSRSLQLKE
HTAISMYVLEGSCFSSASSTEHHEQSNKETKILDEAKQDISKRKDDMKETKLDSGVLVCC
ENTVRLYNTKSVIQGEDKPFCKVKLAKPCSWTSIFTEDDKGFGLILVYHSGELEIRSLPG
LEVLAESSLTSVLRWNMRLNMKLASSTDHGHVFLANGSELAFISLSTSEIEKRFLESLPL
LHDEVLAAAADAAISFSIKQKKQVPHAGIIGDIVKGFKKEKQNDANDSIPACNFTQIGEI
FSRPIVPESSMTAEKYEEEEEEELDIDDIEIDEPVMVASTSSHQAKGKTTKSERDKLFDG
APADLKPKTRTPEEIMAKYKGAEYAAAAAERAKNKLVERQEKLEKISQRTEDLRYEAENF
ASMANELVKTMEGKKKWWKI
>Sgl51711 E3_activity/RING/PHD 35.2 8.8
MSSSNPRTVEEIFKDFSARRSSIVRALTSDVDEFYGLCDPEKENLCLYGHPNESWEVNLP
AEEVPPELPEPALGINFARDGMNRRDWLSLVAVHSDCWLLSVAFYFGARLNRNERKRLFS
MINELPTVFEVVTEKKPVKDKPSVDSGSKSRGSTKRSNDGQVKSTPKLTADEGFEDDEDE
QGETLCGSCGGNYSADEFWICCDICERWFHGKCVKITPAKAENIKQYKCPSCSLKKAGRS
H
>Sgl51715 E3_activity/RING/RING 19.2 13.8
MAETSSVPPPSPPSPTDEGPSSSSTTSFGGQSRSSEVEERVDEPSEAVPQPPAMTYRVRS
SSRYTTTTDDHSADDNFSCAVVVLTFWFFVSMTLIMGIFGSDTLQVGPNSSILLRPNSLF
VESLKVETSDDTEAAPVLYGFYETPPLENTKLWSESVNATIQPGYHKEWIYYLNKGSQMN
VSYNVVGSSSLLLVVAKGVEGFAEWLEDPSYPDSTLSWNIIRGRGSLRQDITRSYDYYVG
IGNVNSMRVKVELNFSIRSSMHAITDSYYKCGLRNSGVCNLKIPFPGGTAALLTTPEPLE
ATGGNRMKVKLSYEPRWLTYFLGIGGMTSIMLGAFNLLNKIRRNMQDDTENQSVDMGSER
APLLSRKDDDLLSLGSSYDSASQDGDEPQEDLEEGCKRLCVICFDAPKDCFFIPCGHCAT
CFSCGIRIAEDAATCPICRRKMKKVRRIFTV
>Sgl51749 E3_adaptor/Cullin_RING/SCF/F-box 26.8 0.0
MSNLDEEDEFLAQFLESEVLSEGSDQDDDTKDMERPMKRMCTEDILRETNNHACDSDGDC
GAKVKSSSCSGSSTADVNAERRIETGILSKIPPELFQHILKFLSSEDLFSCSRVCKFLNN
VASEESLWHRLYCLRWGLLPPTKKLRDHAWKKLYIQRDERDMVLSMKNCQPEFKEYYLQM
YAAKRSQAPLRSQVNDDLIFVDKTVADQVSIWKRSRGLSDKVVTDHTCSGEVCSYFQIGN
VFICEKTGNVHVCDDTCKEVIVDPENMLLVCTISGRCYDRVVSQSDEEDEFDREQQQGAA
VDEPEVFIGKGRFARAYMMGYNCEDEKELEDALRYV
>Sgl51768 E3_activity/RING/RING 29.3 7.7
MGSGSSKTRRIGGSSASSASSTSSFSSSVSSSVGRRSKTRGVFSSSCLGSSSRTYGSDDD
DDDDDQVSDRHVEAIRTRLQRPRTESDEVKVDCYQASKIDEPNNLPCVSSNTELGEWDYA
NGVDNGIRADESSSQAFSGQSMNHSNRFLSRFSFVPGSVSFRLNRAASVGSSRAYPSSPT
SFAVSSNEGDRHVPGGFPNRLGISNESQHSSSLNSSCPTSATVRSHGNSSINLVGHLANS
TLSSSLQGNQAISAQDLEDNDSERIRPGVCLPSLGRHMEMEGLNRRIGDRRNGAREPAER
NVRFSRTLSVGRLRDRVLRRSSFSELTLSPLEQESAAASDGNSVNSLMPSPHLLSSLPNS
YHPSQSNDVENAHLREGRHHDLLEHRSNFLERRRRIRSQVRALQRLGSRFDNLSGHERYC
ILSGQHRTGRCSCRTGTRDSNSNNDGGARASISRIVMLAEALFEVLDEIHQQSVVLSSRP
SVSSIGSVPAPSEVVESLPVSDRHVEAIRTRLQRPRTESDEVKVDCYQASKIDEPNNLPC
VSSNTELGEWDYANGVDNGIRADESSSQAFSGQSMNHSNRFLSRFSFVPGSVSFRLNRAA
SVGSSRAYPSSPTSFAVSSNEGDRHVPGGFPNRLGISNESQHSSSLNSSCPTSATVRSHG
NSSINLVGHLANSTLSSSLQGNQAISAQDLEDNDSERIRPGVCLPSLGRHMEMEGLNRRI
GDRRNGAREPAERNVRFSRTLSVGRLRDRVLRRSSFSELTLSPLEQESAAASDGNSVNSL
MPSPHLLSSLPNSYHPSQSNDVENAHLREGRHHDLLEHRSNFLERRRRIRCYICLLEYEE
GDDMRTLPCHHDFHKKCIDKWLKEIHRVCPLCRGDICRSDSVPVEGGSC
>Sgl51866 E3_adaptor/Cullin_RING/DCX/DWD 91.8 18.6
MEEEDVFPPSSSSKPYLINHPSKIARPSLNLDKIEEGPTTPSRVIDRMINSNHFPSPSRT
ILSDRFIPSRTSSNFSLFSLTSPNSSSSSSTSTPNSNSNSTPQSSKQPDGARDDSSSAYT
SLLRAALFGPDSGSFFPGTPDKGPQNRNIFRFKTETKRPLPSLMPFGPDDSLPGVSYSPV
KSPRKVPRSPYKVLDAPALQDDFYLNLVDWSSHNVLAVGLGNCVYLWNACSSKVTKLCDL
GDDDNVCSVGWAQRGTHLAVGTNNGKVQIWDASRCKRVRTMEGHRFRVGALAWSSSVLAS
GSRDKNIYLRDIRAQDDYVSKLTGHKSEVCGLKWSYDNRELASGGNDNRLFVWNQHSTQP
ILKYSEHTAAVKAIAWSPHLHGLLASGGGTADRCIRFWNTTTNSQLGCVDTGSQVCNLVW
SKNVNEIVSTHGYSQNQIVVWRYPSMSKLATLTGHTYRVLYLAISPDGQTIVTGAGDETL
RFWNVFPSSKSQNTDGELGFLSLGRAQIR
>Sgl51898 ULD/UDP/UBQ/UBQ_Other 46.5 0.0
MMKKANINNNINVGKMQGHEWEMRPGGMLVQKRNLDSNKNNSIPFPFPSIKVLVKFGSSF
HEITINSHATFGELKKRLSEVTGLHPQDQKLIFKERERESNSFLNDSGVNNGSRIVLVKN
TVIIQDKTFTDSRRNLTMDRALKSVAEVTIEVDKLVSQVTSMETVIWKGGSVAEKELLSL
IELFMAQLIKLDGIVADGDVKLKRKTQVNRIQRYMDNLDGLKAQNAMAIRNGGGGGGGGQ
VGLIVSQQQQGRPLIIQQQREQRKFSGMTSKWEKY
>Sgl51905 ULD/UDP/UFD/UBX 48.9 0.0
MATVNQEAIETFMSITGAPETVAIQRLQEFGGNLNEAVNAHFSEGDRNVMQEAPITGTGT
PNDLMDIDDPPVLEPRGPASLLSASRGMNPFSLLDPALRSSLLDTRNIFDTSPELMGRAP
IVTQPREVRQIPIEVKDDGDTLAAPSGHGPRIEDVTDIIDAEGPQIHGTVVAADENDDAI
SADIGATRSSSRPSAPQFDDASGYANDIEEEMIQAAIEASKRDAELQNNQGLDAVSLQQG
PPHRDDAEIAHAVSLSLKTAERESLKREGSLKAGASGSAANDPVEMEELGKIDEPIRRQG
VSSSDKSSSSHNKIEAGGPSIQDEVDELDEHPLVRNRSRRRSAVSTRNPREVGESVASPA
GNPLEPTVASQAHPNGNAFPTDEWGGISSEEHDEAVMLEAAMFGGIPESGYRVPFAPHQM
MHPGVDTSWRMPRPPSPGLVAQRAIREQQDDEYLAALEADREREMKAIEEEKAAREAALE
EQKRKEEESRKKFEEEQELERQLAAKEASLPEEPSLDSENSVTLLVRMPDGSRRGRRFHK
SDKLQSLFNFIDVGRAVKPGAYRLVRPYPRKAFSSEDSNLSLNELGLTSKQEALFLELI
>Sgl51919 E3_activity/RING/RING 31 13.1
MSSLDASPFISPPPSHPTTARAQGVSYATRMIQRASGLGRYLRAASVTVRETAAREIEGR
QTDWYYSHPIVVLDAIWNLAFVLAAFTVLFLTLSDSPRLPLRVWIVAYALQCLVHVFCVS
FEFRRRMRTSIAVADATHATEDNSEDSGTMIKQLETANTMFSFVWWILGFYWICVGGNGL
LIDSPLLYWLCIAFLILDLCFAFFCVILALAVAVAVCFCLPCIIAFLYVMQDLPQGASKE
DVGLLRKYTFFKCDSKEINGEIESSCGGIMKECGTDSPVERTLTAEDAECCICLGAYEDG
TEVRELPCNHHYHCSCVDKWLYINSTCPLCKYDVLKGTYDDGEV
>Sgl51942 E3_activity/RING/RING 31.7 3.9
MMEVQPSFSQFLQQNSGMEVVELARTAVNTLNKLANWGQYSNQPGVGPKEGDVLMDFLAK
IDGRLVRVARKRAKVSGRNFEEVFAETKFEFYFNEAKFMETEMLVDPREEVVKVARTVTE
ADKGEVCGVCQEEVEEGDVVVTTACMHTFHGLCLWTWLNGRKTCPLCRFTVLQSYDDRI
>Sgl51980 E3_activity/RING/PHD 54.6 53.9
MGKGRPRAVERGGGLGQISAANGSMNINPAPVYYPTEEEFKDPLEYIYKIRGEAELFGIC
KIIPPKSWKPPFALDLDSFSFPTKTQAIHQLQARPASCDSKTFELEYNSFLESHCGGRKP
RRKVVFEGEELDLCKLFNAAKRFGGYDKVAKQKKWGEVFRFVRPSSKISECAKHVLAQLY
LEHLYDYEEYYNELNKGKSKGCKREMHSRDRKRDQISDSSSSKKRQKGDSGEAVKVSKDS
KPKKEERDQICEQCKSGLHGAVMLLCDRCNKGWHTYCLSPPLDAIPLGNWYCLECLNSDK
DNFGFVPGKSLSLEAFRKIADRTKKKWFGSASCSRMQFEKKFWEIVEGSLGEVEVMYGSD
LDTSVYGSGFPRSNDKRPESIDGEVWNEYCNSPWNLNNLPKLKGSMLRAVHHSIAGVMVP
WLYMGMLFSAFCWHFEDHCFYSMNYHHWGEPKCWYSVPGSEASAFEKVMRSCLPDLFDAQ
PDLLFQLVTMLNPSVLQENGVPVYSVLQEPGNFVITFPRSYHGGFNLGLNCAEAVNFAPA
DWLPHGGFGSELYKLYHKPAVLSHEELLCVAVKIGCDAKVAPYMNKELRRVFSKEKIWRE
RLWKKGLVRTSVMSSRKHPDYVGTEEDPTCIICQQYLYLSAVVCRCRSSTFVCLEHWERL
CECNPRKRRLLYRHSLGELGELLAMTENVTSCSNGNPRRNVLPRQNICSIDSDTLTKKVK
GKQMSFAQLAEEWLLNSCKILKLPFSSSAYASALKEVQQFLWAGHEMDPVRDVMRNLVQA
KDWAERVRNSLSAVESWSENGAKDVDKVHLEHINNLLKHDLLPCNEPGHLKLKEYANSAS
LLAQEINNLLSTSKFSVAELENLFNQTSSFPIYIRESETLARKISSLKVWLDSVKKCVTE
TSPAAIEIDFLRHLKEEMLELQLHVPENEKLLELIGQAELCQAQCNEMLKGSITLEKLEL
LIYEFGALVVNIPELKVLQQYHSDTISWLSRFNNVLVDINEREDQENVVEELRCLLKDGS
ELRVQVDELARVDVELSKACCREKALKVRRYKTEIGFVQQVLSEAAVLQIESEELFVSLS
QMVATAFSWEERVTKILAFESILDEFEDAIRSSEDIFVNLPSLPTVQDAVSAAYAWLESS
KPFLQASVPTTSDSNDALVFEDLKELVYQSKFLKVKLAEIGLIEAILKKCEEWRHRACSS
LKDVEELLNRKDIFSRLHCDVILEIEELRAMVVSVANAGQSLGFAFPEVSRLWNAASTLK
WCSKVLIFHFEPPSLQDVDNLIEEMKDLPIGEAVAFVLVSLVDAVSWLKKAAVFLSVSST
EEKRKCHLESAEDILVKSQDMLVSFPAINVQLEQAIKKHKLWQEEVQAFFSDNSSDRSWS
SLLHLKELGKGSFDCLELDMIMSEFETVGNWKRRGEELVGCSDGDATNLFSSLLKIKQSL
HRSLYIYEKSRCWKVRYFCIGCSSNSDDLEFVTCSTCKDCYHLRCLIPKSVGSNSTKEYI
CPYCVLVDSGSICRSKDSPLRYKGKRPELEKLVELSSDAKKFATRLEESDLLQEILDEAL
ACRDCLSGVVDSALSIFDNDVSSISGKLTIALKGLDVAGVCDSVAIRKFDQALARNSWRI
RAFKLVDGSQKPVMQQVQRHLKEGSAISVPPEDYFRQKLIGMKEAGMRWVEMAKKVSSDS
GDLELDKVFELIAEGEKLPIHFEKELKLLRARSVLYCICRKPYDQRSMIACDECDEWYHF
DCVNVISPPDTYYCPACKPRMEGKMPMSPSVKQERSQSAKDNEPQTPSPRHVESRWRPKK
RKPSMKRKVFVAADRKSLLWSSGFDKLLWRNKKPFRRTVKKRTELGSLSPFFLLQQ
>Sgl51992 ULD/UDP/UBQ/UBQ_Other 36.5 0.0
MMGTMPILPLPAPPEDGNLGPTPLSQLPPDHDEKKEVDDQQKSGKPDSVATHTRTIGIIH
PPPDIRNIVDKTAQFVAKNGPDFEKRIIANNAGNVKFNFLNASDPYHAYYQHRLSEFRSQ
NQSTVQQPSSQLDSEAEAVAAAASDGASAAAEKPDPAAQFRPVRKVLEPPEAEQYTVRLP
EGITGEELDIIKLTAQFVARNGKSFLTGLTSREMNNPQFHFLKPTHSMFMFFTALADAYS
KVLMPPKGLTEKLKKSIADRTVVLERCLHRLEWEKSQEQARQKAEDEIEQERIQMAMIDW
HDFVVVESIDFADDEDESLPMPMTLEEVIRRSKITTKDEEEIIEPGKEVEMDMDEEEMQL
VQEGMKAATLEENGEDKTNEVKADMDEDEAPMRIVKNWKRPEDRVPAEKDPTKFTVSPIT
GELIPISEMSEHMRISLIDPKYKEQKERMFAKIRETTLAHDDEISRNIVGLARTRPDIFG
TTEEEVSNAVKAEIDKKKDEQPKQVIWDGHTGSIGRTANQAMSQSMGGEDEANNDGRPLP
GPAAPPPPRPPVPMIRPLPPPAGLAVNMPRVPTSNVQYSAPNSAGLMAPPPPRPMVGVNQ
MVPPPPPPMQMAPGQQHMMMNRPPMPPGSMNQSGMQVPPAPGSQFTPLGVHRHFTPVPPH
GMPVGPPQPMSQGMPPPPPPPPEEAPPPLPEEPEPKRQKVDDSALIPEEQFLAQHPGPVR
INISVPNIDEGNLKGQVLEITMSVNETVGSLKEKISGEIQLPSNKQKLSGKAGFLKDNLK
LAYYNVGDGETLSLSLRERGGRKR
>Sgl52019 E3_adaptor/Cullin_RING/DCX/DWD 25.4 0.4
MNSLIDSQNPKSNSSSSSNIVTLNVGGELFQTTQQTLTLAGPNSILSSSSSSSSNSSSNS
NSDIPFFDRDPQLFSNILSLLRTGNLLPNFQTVDLPNLILESQFYGIEHLLTDCLSNPSQ
FNPLNLQNSLILPLNGRDFPSVISSTSIGSVHVAHGCKITSFDWSLTRKSTVLTQFVAID
SLVALSPDLAAAGATDFSGLQIIDLEKGSVKENLNWVNSTRSSSTVQAIGSSNEHLFTCF
ESGRRNSNAIVVYDRLGDFRPVFEIARNEIYGAEFDCSTIPATKLSWVSSYNLLMASGSH
SGPTGVSGSIKLWDIRSGNVVWEMKETVDCYADVSVSDSSSCMFKVGINSGEVFFLDLRN
LTPESEWECLGNRAKLITSKKEGLGCKVECHGSDVFVSKGGNLELWSQVMVKSTRSGENV
VDDRVFKRTLMGRAKDMNGNRITNLRFGGNKMFVTRKDEQFVEVWKVSN
>Sgl52028 UBD/UBC-like/UBD_UBC 100.8 0.0
MSSPSKRREMDLMKLMMSDYKVEMINDGMQEFFVEFHGPTESPYKGGAWKIRVELPDAYP
YKSPSIGFVNKIFHPNVDEMSGSVCLDVINQTWSPMFDLVNVFEVFLPQLLLYPNPSDPL
NGEAAALMMRDKAAYEQKVKDFGSCCMRILATSNLDRSGVRMFPVALGRNREGGGGLWNL
DQLTRPVERLSSSSFSAVLLFHDHTKKLSHFPEYCEKYAKLEDIGAAQEEEISSEEELSE
DGYPSSDGDDEVAGKVDP
>Sgl52043 E3_adaptor/Cullin_RING/DCX/DWD 25.4 0.4
MNSLIDSQNPKSNSSSSSNIVTLNVGGELFQTTQQTLTLAGPNSILSSSSSSSSNSSSNS
NSDIPFFDRDPQLFSNILSLLRTGNLLPNFQTVDLPNLILESQFYGIEHLLTDCLSNPSQ
FNPLNLQNSLILPLNGRDFPSVISSTSIGSVHVAHGCKITSFDWSLTRKSTVLTQFVAID
SLVALSPDLAAAGATDFSGLQIIDLEKGSVKENLNWVNSTRSSSTVQAIGSSNEHLFTCF
ESGRRNSNAIVVYDRLGDFRPVFEIARNEIYGAEFDCSTIPATKLSWVSSYNLLMASGSH
SGPTGVSGSIKLWDIRSGNVVWEIKETVDCFADVSVSDSSSCMFKVGINSGEVFFLDLRN
LTPESEWECLGNRAKLITSKKEGLGCKVECHGSDVFVSKGGNLELWSQVMVKSTRSGEDV
VDDRVFKRTLMGRAKDMNGNRITNLRFGGNKMFVTRKDEQFVEVWKVSN
>Sgl52056 UBD/UBC-like/UBD_UBC 103.1 0.0
MSSPSKRREMDLMKLMMSDYKVEMINDGMQEFFVEFHGPTESPYKGGAWKIRVELPDAYP
YKSPSIGFVNKIFHPNVDEMSGSVCLDVINQTWSPMFDLVNVFEVFLPQLLLYPNPSDPL
NGEAAALMMRDKAAYEQKVKEYCEKYAKLEDIGAAQEEEISSEEELSEDGYPSSDGDDEV
AGKVDP
>Sgl52058 E3_activity/RING/RING 31.5 10.2
MVGCCCCCFPSRRSEPVRTPTYYYCPRTSEEREPLSANHGIPPGLGGGLLVDTNLDTSSL
DTYISPPAPIPYDSDLGRPRTPLGRDNNLSKSNTSAGVANSGSEEGLNNADSIENQEKVM
KELDDKAQSVLDLNLSEDSDDDLKKGVEANLTIIEEEDCPICLEEYTEENPKMVTKCEHH
FHLCCILEWLERSETCPVCDKEMLIDEAFNL
>Sgl52061 E3_activity/RING/RING 31.5 10.2
MVGCCCCCFPSRRSEPVRTPTYYYCPRTSEEREPLSANHGIPPGLGGGLLVDTNLDTSSL
DTYISPPAPIPYDSDLGRPRTPLGRDNNLSKSNTSAGVANSGSEEGLNNADSIENQEKVM
KELDDKAQSVLDLNLSEDSDDDLKKGVEANLTIIEEEDCPICLEEYTEENPKMVTKCEHH
FHLCCILEWLERSETCPVCDKEMLIDEAFNL
>Sgl52075 E3_activity/RING/RING 26.6 9.7
MGFPAGYTEVLLPKLLLTTLSLLGFVRRFILSFLRLMGLSSLVEPATEPDQPDPIPAQSV
SSAAALIREMLPAVKYSEIAPSSGHCGPEDEPGPTESCAVCLYEYEGEDEIRRMRNCRHM
FHRCCVDRWIDHDRKTCPLCRKPFVPDELQEDFNEKLWAASGIPDFYSEYSPITNFL
>Sgl52085 E3_activity/RING/RING 31.9 8.1
MGFPSGYAEQMLPKFFLNSLSLLTFVRTLILALLKLIGLSHILEPQICWPEPEPDYRPIS
ASIIQEMLPILKFSEVSSGQPEPGPCDEHCAVCMNEFRDHEEIRQLTNCRHIFHRVCVDR
WMDHDQITCPLCRALFVPDDLMESYHEKLGAATISAAIPEFGGEFSVINSFL
>Sgl52089 E3_adaptor/Cullin_RING/SCF/F-box 18.1 0.0
MADLLPTILCDVMFEILGWLPVKSLLRCKSVCKDWYNLINTSTFVEHHLKQSINNSHHLC
HRQRPFVFASRKSLYLGEDIDFPKKLIELKLLFKDNENALLEYDDAHIIGLCNGLVCLRL
GSTPKYFAICNPLTRTCKVVASHGEEMGHNLWYPMYGFGYDTQTDEYKIVVITMGRDRQI
WIYSFKKNSWKKGSSDRLHQPPFQKNIYHNQLAYGIFGHGMLHCIVRGVEDGIRAILGSV
DDFMYKELPQILRFNFSSEDWEEDLSFPNLSNNLSEYMYVEARILDGFFCIATYDLWEKL
NIWIMKEYGVEKSWTKLCNCDLSSYNLIAFSRTRPNGLWFNTRSQGLVWYDPKQETKELF
EYDSPFKNVFHYEVTLCGQSLVSIPGSSYMIGEEFQAEIQR
>Sgl52120 E3_adaptor/Cullin_RING/DCX/DWD 36.5 10.9
MAMRCRSIVGIWSETPPSHRITAVTTIDEPPTLYTGASDGSVAWWQLSSLTIKPVAMLCG
HVAPIADLCISYPLLASVDENSNPSRDVGHNSLPGDQAALISVCIDGVVCVWSRGSGHCR
SRRKLPPWVGSPFIIRTLPTNRRYMCMASCFTETSQTSESDFVDSGEGNEVTGNEESLGR
KPPKCTVVIIDSYSLNIVQTVFLGHLSIGPLEFMEIVEPVADSQKHSILLIDSYGNSQCI
PLVKDSHLNEGEPKLHQNSSLVNTAPLKNGPYEGEMVLCVSTYGQLLGLVCKTRCIFLLV
SSDTVVGVLSLKDNSHHGVDCTLSHVTGGMFISSNNTSISESGKTHMFGLKFSVWDDRGS
VVIYELSYVNDIFKYEISNEIPAITCPIDVKVSIKIVQLSNYFLRVESICFRNEEPSLWR
PHVTIWSLHQQLDDHESFGKNCRLLGEGNFLVDWVDYSSDAINNEAPENTSGEKSATGGP
SSSSYKNNLNCTSVWKESIVSSTMVISLNAHTPYAIVYGYHSGQIELIQLNFLAPKIDSD
AVNLHPELECLGSKRHFSGHTGPVVCLAAHLTVGNSTERASKKLLLSGSMDCTVRVWDLE
TCNAIRVMHHHVAPVRQIILPPLQSYHPWSNCFLSVGEDSCVALVSLETLQVERMFPGHP
SYPLQVVWDGVRGYLACLSQNNSVTSGTKDVLYIWDIKAGSRERVLRNAAAHSMFNNFCK
AKDTNNISGFASNYNTSRSSFIFSLTEDGSSLSSKMENNMSISSSVVNPLDRCMSSINNS
SARSVKLRTGNYDKHAIRCSCPISGIAILNFDLSDLLSTDICGDGENHFRAPSNESQQRT
TSYDSSEQGNFQKIMQDDQCVETFKLCLLQFSLSFLHLWGVDAELDHLLEMEMNLKRYEN
VMSAPGLEGDGGSVTLAFPAFSSALQLWQSSSEFCAMRSLTTVSLAQSLVSLSHSCSGAS
SALSAFYTRNFAEKVPDVKPPSLQLLASFWQDEDEHVRLAARSLFHCAASRAIPPPLCCS
RTTEHTKTADHVDQVGRSEREYQKRTETGAGFLLAERPETLGDSQVGEAEMMKWLESYEL
QDWISCVGGTSQDAMASHIIVASALAVWYPSLVKPSLSVLVVRPLIKLVMSMNEKYSCTA
AELLAEGMESTWKECIGGEIYSLIEDIFFQIECVSGASTNTPSAAAAVPPKLRETLVSIL
LPSLALADIPGFLSVVEGLIWSTASDSPVHLVSLMTLIRLMRGSPRHLALYLNKVVNFIL
QTMDPANTVMRKSCLQSSMATLREVVRVYPMVALNDTSTRLAVGDAIAEVNSANIHIYDM
QSVTKIKVLDASGPPGIPTFLSGAPETVVSAISTLNFSPDGEGLVAFSEHGLIIRWWSLG
SGWWEKLSRNFIPIQCTKLIFVPPWEGFSPNSSRASIMANIAANGRHSQVHTRSSDIDSL
NLLLYNLDLSYKLEWVVDRQVCLTRHGQELGTFLL
>Sgl52121 E3_activity/RING/RING 20.5 4.4
MSVVQIAPNQTATPTNDDVSGKSQTQLALELNSCRIIAVAEQLLMCAQSGDQPFKVHQLC
LSLARGIDYGLANNEVPAAASQLPQVLKMVCSRKNDVNLQAGIMVLMISVKNACKLGWFT
ANDTQELLTLADEVASYFVTKKDTGVCNSLPTVSTIMSRFYPRFKLGHVISFLEVEPGYG
THLVDFHISKDVAFSKEERIRLFVAMKDNIDTSSCIITPQQVNILLNGKPVEHRNSVLMD
HGPQLPTVVNPSLKYGINLLQVMGQFNGHYILIVALMNVIPSSDLQPPVDYVQPASAASS
SDAEIIEGSSRVSLRCPISKTRIRTPVKGSSCKHYQCFDYNNYVEINFKRPSWRCPSCNQ
SVCFTDLRVDQKMVKALKEMGENVSEVIISVDGTWTPASSDKRKDESHHKTSANQQEGQV
LEVSSGMLDASDNMCDLTGEDDEMDTDSRSEPVDTKPVIHHHAQGQSAPSNCTLPQASRS
TIEVAQYSSGQVVNSASPRTMFNSGSAGFNFRPHAQLGGTSRTLTGNGGVTPVLTDAVSP
ALNRQPDNFQGTNCSPSLNRQLQEALFSPGLMNNNLHLIPRNVTRVPNAIQALPVPTTPQ
QHSRPTVSSPTGSGSTPFQRSVAGSNARAPSPYSSNVERQRHLSQSFAGSHMSNMPSLQP
LNRSASPGVGISNPSHNMPMPQTLSQPPHLMRTSQLPRNHMQHGTGPRMAVNNSPSTLQR
VQLTPQQTSHVRQQPQIQTQAARMMSSLPLNSGVIPQAVSRTESLIDLQAEQNWRPSGRM
RGALTGKAYSDALNQFMGQAAPPVQTQSPRPTVSQSSTPPIVNNILLANRRIASEVQDRS
GAGSGTVNTQEEGSG
>Sgl52140 E3_adaptor/Cullin_RING/SCF/F-box 19.2 0.0
MDMEPGPSWEDLVLQVSEENHTSEPNVVDSFVGLTYVDDENKDVVCINSILPDDILEQVL
GHLPISTVIRAGSVCKKWNDVSQTGRFIQNLPNTSPQKPWYFMFTGDSDPLGHVYDPILL
KWFRFEIPYVETSSWYIVSSSGLMCFMDNDSRRKLYVCNPITKRCRKLEKLSSVEVSDYC
ALAISLDKSSQNYIVTIVRSIQAPTEAMDWKLSIDVYSSENDSWACPVNVTLQDWRGGFD
SVICGRVLYFVVYQTRTMGFIRPRYGVMAYDLASESFDLDMDEPIIRAPCPITCMRLMNL
EEELVMVGGIEKQGRPGIIKGIGIWVLKGKEWEEVSRMPNKLFKGFGEIDDVFSSSGFNK
LIYIQGYGSPALLMFEMNSKEWSWAHRCPAIKKFPLQLFSGICFEPRLDVSP
>Sgl52141 E3_adaptor/Cullin_RING/BCR/BTB 32.2 0.1
MASPNDSNSTDNGSVHNNSVADPLFISNSDNPTHSLTNVVFSGVNFVRWKRNIHRALGAK
NKLGFLDGTIAVPDESNVLEYQKWKRADYMVVCWILSSMNGELADDFSYAESAVELWHDV
CERFGQSNGPLIYQLRKEIDALKQENLSILSYYGKIKRLWDELQSLKSSPMCTCGALNSC
SCNFLKRLSDCESEDKMMQFLLGLNPVFDSTISQILSMDPLPTMNRAFSIVQQIEKQKEI
SATHDGAVPESSAMAVQRFNKPFGAGRGGYQQMNSGRKDWRKDKMTRFCDFCKGKGHFAD
QCFKKNGYPDWYTSLKGGKPAVAANAAVTDEAIGDSPLDSGSNSHGVDNSFLNSVCQEVI
KAMQGKQLSESGGCSSFANCAGTIAYSLSCNTIGCVDKMTWIVDSGASDHMVCDSSCLTS
IRKLDVPIRVGLPDGSCKMVNVVGSVKVNDKFVLHDVMLVEGFKHNLLSVGKLLDTSSIN
VQFTRNGCIFQDHSSKVVAEGVKVAGLFLLQNNQATAGAKISASSSTSCNNVSGDLSKIP
LDIMHSRLGHVSLSKMKYIPGCNCSGLKSYDCEICVCAKHHKLPFNKSMSRADSAFELVH
FDLWGPYKIMALDGSKYFLTVLDDYSRVTWTFLLQNKLQVAKTISNFLAYVANQFGKSVK
VIRSDNGTEIIKEQCLSLFLEKGIVHQRSVPGVPQQNGRVERKHKHLLEMSRALRLNASL
PKKFWGECVLTSTHLINKLPTKVLNWKTPFEVLFGKVPMYDNLRVFGCLCFAYNKNSKSD
KLESRARRCVLIGYPFGQKAYKLFDLESKVTFVSRDVTFQESIFPFKTDNALLPISPKKA
PTLISFGSFEPEFLPTPPTSSAPISQLLPPTDSSVSTSSQSFSTAVPVPFTTEIPISSSQ
TQAPVKSSRVVNPPAKYMLRVQLSLVTEQQIYSISKEKDYETYSTSTTITGSGDETLQNN
DASLNMDCLVEVKTIHISSPILAAKSPFFYKLFSNGMMESEQRHVTLRIHASEEAALMDL
LNFMYSNTLRTNTPPGVLDVLMAADKFEVASCMRYCSKILRDFPMTSESALLYLDLPSSV
LMADAVKPLTDSAKEFLASRFKDMTKFQEEVMNLPLAGIEAVLCSDDLQIASEDAVYDFA
VKWTRAHYPKLEERRNVLGSRLCRLIRFPHMTCRKLRKVMTCNDLDPELSSKLVTEALFF
KAEQPYRQRALLADETKTSGHRYVERAYKYRPVKVIEFDTPRPQCIVYLDLRKEECQKLF
PSGRVYSQAFHLGGQGFFLSAHCNMDQQSLFHCFGLFLGMQEKGSVSFAVDYEFSARQKP
NDEFVTKYRGNYVFTGGKAVGYRNLFGTPWTSFMADDSLFFINGVLHLKAELTIRQ
>Sgl52160 E3_adaptor/Cullin_RING/DCX/DWD 87.4 14.4
MDEGYADDVTTVSQAEDVPAQGKDQVLVESRNVLEPRGRVITGEGNMRRSSIQQFVDILG
GQDASSSVNIVEIPEGPCSSYQDAGEGRVQELTLGNYTTGFNTVNEGEMMNTILNEWQHG
NQTGLGSEAETTNEHPTHKEKSSRSSALRDSRPANVLDGQGFNHEASSSPGRDDCDAVLQ
HAFSSGPMRMKILSRSSECPEYFVKDTLKGKGILCRGPTSAGEYKGQNTVKAVAAPMLAS
NPSVKIGENFVIPSKCGNVASYGNKSVNAGTNLREWMRSRQKLLNKVDTLDTFKQILDLV
YLLHSDGKVLVDLRPSFFRLLPSKTIQYSGRVCAQKEMLGNVTHKDFHKSHPRKRQLEQG
MSPHTYLSAKHQKSIDKANFLKMKSQFQLGYGPRPITNKVDANLAGAGPADSKISSRLHL
PPSAQQHAVFAEEQQEEKWYRSPEELLGRDCTSSSNIYSLGVFFFELLSSFDSVKMQTTV
MSDLRHRILPPNFLSESPKEAGFCLWLLHPEPSLRPTAREILQSEVMREIALCGDEKSSS
IQEDEGESEMLLHFLLSVKEQKQRHAAKLVEDLGCIESDIKELENRHLKNSVIVSSTGED
LLYARQRDFLFHENGLPNPVSDGGDSRFLKNAVQLENAYFSARSQIHHPVIDSRDQDDRG
VLTIRDDWNSNQNEEQKPLDDRGAFFDGLCKYARYSKLKVCGTVRNRDITNSTNVVCSLS
FDRDEEYFAAAGVSKKIKIFDIQALYDNSVDIHYPVVEMVNKSKLSCVCWNNYIRNYLAS
TDYDGIVKLWDANTGQEISQFTEHEKRAWSVDFSLLDPMKLVTGSDDCCVKLWSINERNS
LHTIRNIANVCCVQFSPHSSHLMAFGSADYKIYCYDLRNANSPWCVLAGHEKAVSYVKFV
DSGTLVSASTDNTLKLWDLSKTSPVGLSNNACSLTLEGHKNEKNFVGLSVSEGYITCGSE
TNEVYTYYKSLPMPITSHKFGSIDPISGKETDECNGQFVSSVCWKGKSNVIVAANSSGCI
KVSDCISLIVWLRFGAFPIRIHSIKGRNCKNHLKGMTIRYLLFIS
>Sgl52175 E3_adaptor/Cullin_RING/DCX/DWD 37.9 5.4
MEKKVATLEKGTLCSAWNYSAQRLASASINGFLTIFDSPDSASSSPFSPSSSFQVHKGSI
LKVVWVPPEFGDAVACILDDGTLSLWEEVAEDGKSLQWKFCTKFHNDGARVLDIQFGGTS
TCLKLVAAYSDGYVKIHELQNPLELNTWQLQAEFQNVIDSVSKYAKVLCSSASISWIPQR
GENQQLSFVMGFSSDIPQLNSSKVWEFDQLHQRWLSVAELSLSENSGDPVYAVAWAPNIC
RPYEIIAIATEKGIAIWHVGLNPDVNGHLSVENIALLSGHKGEVWQMEWDMSGMTLASTG
SDGLVRLWQSNLNGVWHEQAILEPAS
>Sgl52209 E3_activity/RING/RING 28.9 7.2
MNQYSLILSFFFFFVIILSNLTPSQLCSSTSIDCSSQPSFQTHFPFRIPEFETTRCGYPG
FELSCSSNGSTILSLPSLSQPLRVENISYEHQYILLSDPNLCTPKWAMDPYLVSTPFIVE
PSNAVNDEPRYYAFVNCSGPPLMNDEVPFGSSVISCMSGADYTIVATLRNDAEKIMVDRG
CQVVKRMSETEFWWEGKMMNDVENYPQDFSRVFLLLSWDEPDCSACTSNGSSCGFAADSG
LDVACYNAGAFADGIIPTHSKWDYIVLDIVFPLSMLIVLLSILIVCCNPNTNTESSRYEF
PQQMLPRLGLDESIIESYPKTVLGESKRLPNNLGDNICSICLSEYEAKEILRTIPECQHF
FHADCIDEWFRMHTTCPMCRNSPQPSPALAA
>Sgl52237 DUB/UCH 265 0.5
MQTSKVILIMSWCTIESDPGVFTELIQQMQVKGVQVEELYSLDLETLESMRPVYGLIFLF
KWRPGEKDDRAVVKEPNPNLFFASQVINNACATQAILSILLNSPDVDVGSELSNLKEFTK
NFPSELKGLAINNSEAIRTAHNSFARPEPFVPEEQKAATKDDDVYHFISYLPFDGVLYEL
DGLKEGPISLGPCTGGQGDADWLRMVQPVIQERIERYSKNEIRFNLLAVIKNRKELYTVE
LKECQRKRERILQQLSSIQSGVTDNSKLEELNKQLAEVNSGIEAATEKIVVEEEKFKKWK
TENIRRKHNYIPFLFNFLKILAEKKQLKPLIEKAQQNKVSNSS
>Sgl52243 ULD/UDP/UBQ/UBQ_PIM 69.1 0.2
MSGGVGVALSSNYEDMVHFPGFFENRVDLHPSESILVYLSVAGSVIPIRVLESDSIASVK
LRIQTCKGFVVKKQKLVFGGRELARNDTLVKQYGVTSGDVLHLVLKLSDLLSIIVSTTCG
KEFEFQVDRFRNVGYLRQRIFKEGKAKVRAIPIEKDVELSVVASDIRPRDNKSDESEKKQ
SSELCNQPIRSTEGTGGAYFMLDSSGQRISAVFKPTDEEPMAVNNPQGLPVSENGEGLKK
GTKVGEGALREVAAYLLDHPKNGPRSSSSREVIGFSGVPPTAMVRCLHKGFNHPNGFEGT
LKDVKVGSLQMFRENDGNCEDIGPQAFPVEEVHKISVLDMRLANADRHAGNILYKKNDNN
GQIELIPIDHGYCLPDSFEDCTFDWYIGHKLANFLFRNNKLHKVT
>Sgl52245 E3_adaptor/Cullin_RING/SCF/F-box 13.3 0.0
MPKQPEKQHYDRLSQLPDDIVLLILSSFPLKEAARTSVISHRWKHLWHCLPTLIFEDVKS
IFYKENKRAR
>Sgl52250 E3_activity/RING/RING 20.2 11.3
MEVELFSNNVLSEEDTVEVDTEFDNLGDEGERCGICMDIVIDRGVLDCCQHWFCFVCIDN
WATITNLCPLCQNEFQLITCVPVYDTIGGSKNDEESDSRDDNWSVEGTNNTLSFPSYYID
ENAVTCLDGDACKIRNGLVTFEETLTLDTSIACDSCDIWYHAFCVGFDPEGTSVDSWLCP
RCLVNEEDQNSDLKELYCTGKNDDEHCFVDTSTGKVSIRVADSGETAVVVSRINGENLTG
EPNVNSLSNQELVGHCKVGKSVLDPDCCTAEMERPLDQGNEGIDTFKPESNLPFSRLGET
VIKCEPEEYESKMSFDAELAFAPTLSDDKALLGQDENMEDVKADVGPKLGAKRKRPGNSF
RKNSDEEPHEGRLVGSSSTKKAKAQRRTRSTMNDQVDVCEEFKKNNKAIDSSADEIDRNI
TMKKNQPIDIMSIVQGTKPIAGNRSVSKKEAGKSAKVEKNAAGLRVKRIMRRPTEEKESD
AVVQKLRKEIREAVRDKPSDEIGKSIFDPNLLTAFRAAVAGSVSEPAKKSTSAMVKAKKL
MLQKGKARENLTKKIYATSSGKRRRAWDRDCEIEFWKHRCRTTGKPEKIETLISVLNLLK
KSPGTKNVDQTSEEEAKAPILSRLYLADTSLFPRKDDIKPVSALRAAACSNHNDKPSTLD
KPPASADDKKSVCTSTKNGSASESLHSAGQPNKASPQKKMTGKTDDVKIDKRKWALEFLA
RKSASDVSSPIHKKEDNAALKGSYPLLAELPTDMRPKLAPTRQNKIPLSVRQVQLYRLTE
HFLKLTNLSIMRRTAETELAVADAINIEKQVADRSNSKVVYLNLCSQEIRNFTNCSSPGT
LGKSTTTSSTVPVLSKGDSEFTPPSSIPIPSTGGQTSTLSLNSEADAALRAAGLLSDSPP
NSPLHEAEYLNGDDNAKGETKEEIDNIFEMNSHPDLDIYGDFEYNLDEEDYIGATVINAS
KAQAEDGESKVKIVFSSLSSIKSDSASEANEQGLPKTDLLLSTPSLLEGPNDVDSGNSPL
EDKVDSISLPGVTTLDGEVEELSVAECEALYGPDDDLANKNISDLAPAEQFALTGSTNVD
VISDKDKVTTDSLQSMTAGEKSSSSLNPKGNDDEEKNSNRKVDKKDEHGDSVLKKVEAYI
KEHIRPLCKSGVITTEQYRWAVGKTTEKVMKYHTKSKNAYFLIKEGEKVKKLAEQYVDAA
KHKAK
>Sgl52254 E3_adaptor/Cullin_RING/SCF/F-box 15.2 0.0
MEVTLSSFLSSQSFIVAFAATLLCGIFAVRFSLSSSSKIDSSRRKNFTTESKDSNSSNNC
VSDCNCSCNGVVLRPDPTVAAVNGGEMPAVAMVAAEKQTGASMMEQLVPEITTHALSYLD
YPSLCRLSMTNSLMRKAANDDNAWKALYHKDFTVEQDSVRPANGWKAYYAATRALVNINA
EFFNIIRERSLPAMSRFWLNADYVKCVHVSGELITGYNAVMQSWQIAFNWNQETDGFQIR
DVRARVLTDMAWITMKTYVGMNGGPYSVTNVFEHHNGKWYMVHHHCSLMLVDEDVEQQIV
HG
>Sgl52285 E3_activity/RING/RING 35.1 10.3
MGRHEDSIPPNSSLYPEELQLKLYQAFIFSIPILFSIILFLLFYLFYLKRRANNNLLAQT
PTTQHSALHSVSFLATPWSLGIKGELKDKLQVILFDEELRERDTICCVCLGEFELKEELR
QLPLCKHVFHGDCIRHWLRNNATCPLCRCPVLSGMKMDCPVGLRQDLTSQENDNNLAPQQ
QEQENVASSTSEVHNSSSRSEVHVIQIVDEPPSSSSSSNHAS
>Sgl52307 E3_adaptor/Cullin_RING/DCX/DWD 76.7 9.7
METACVESDAFYDAPEEISSVSDSESEDSDELQQVGNNGISSLHYDFWSGNPKSIDERRD
DFIRRTGFVLDRCQTAREGPDDATCVTSGMCNDRTESVENEHDEGKELTAGVIQEVVDGG
DQGLLWRIQSLDDRKEFDVENEGIASRKDNAAGVSSRAAIDEFHTAFGTSNLFQQTKTKS
EENGTVCKKKPQCKEGWLKRFSFKAANMFNKDKDHKELLQKCKSLGYRSQRVRVRSHKKW
SKELSSLYRKQEFSAHKGSILAMKFSLDGQYLATGGEDGTLNVWKVIEDEMLTDLDLLRF
SPVSANLNFSVNGVPNLACFLKFKEGRKVINKLKKSLDSEGIMIPRKVFQIVEKPLNEFH
GHEGEILDISWSNNGLLLSSSIDKTARMWKVGCSQCLRVFPHHDFVTCAQFNPMDDSYFI
SGSIDGIVRLWDIQRGQVIDWIDIKEIVTAICYRPDGKGGIVGSMVGNCSFFEIADDFLH
QVSVIYLQDKKTLTCKRITGFQFSPNNPSEVVVSSADSLVRILKGADIICKLRGSLPLID
RGSQVFASFTADGKHVISATDDSNVYIWNHLNKGRITNNKPKNVWSCESFLSQNAIIAVP
WHGITSTSALPPSTPRQPTSTSKYNQKSPVSSSYHTVNHAEVSSMKSSATARDCEALLRS
NQADISPAIGDMEYEFLKNVCEGVLSGSHMWGLVIVTAGKDGRIRTYHNYGLPVRYPTRK
FSLSNIRNRCRENCSNIKGSTSLGR
>Sgl52318 ULD/UDP/UFD/UBX 59.9 0.0
MVDSNDKLAYFQAITGLEDTDLCTEILAAHNWDLELAISAFTGNHDSNPLPSSDVGSSGQ
SIPTSSSNDAVFPPEPNPGNPGIAWRIITLPISVVSGSLGLISGAVGLGFWAAGGVLSYS
LGMLGLGARRGGGPASSPLVEGTPSSAEAMEFVAAMEREYGSLLKVNFVSEGFMDALQRS
RHAYKLLFVYLHSPDHPDTALFVERTLGNEAVAEFVNENFVAWGGSIRAPEGFKMSNSLK
ASRFPFCAVVMAATNQRIALLQQIEGPKSPEEIMSMLQRVLEETAPVLVSARLEAEERRN
NVRLREEQDAAYRAALEADQARERQRREEQERLERERAEAERKRQEEEEAREREAREAAE
REAALARRKQEKALSLGAEPEKGPDVTQVLVRFPTGERKDRRFSSSATIQSLYDFVDSLD
CSTFESYSLVSNFPRTVYGPEKHSLTLVEAGLHPQASLFVEPNP
>Sgl52363 DUB/USP 370.8 0.7
MTIPYYEHANSLDNGVICSPQEQKRIIKELNDQAESNLKEGNLYYVVSTKWYLSWEKYTG
QDNVDCEMNGSSPLQNGVDRPGPIDNSQLVSSVNESDVDNKDLIRTLEEGQDYVLVPDEV
WKKLLEWYNGGPSLPRKLILQGDTNKKFNVEVYPLCLVVTDSRDNSQSDIRLSKKASLLE
LYEKVCTLKGLPQEKIDIWDYFNKQKQCVLLPSNKTLEDANLQMDQHLLLELQNVGEGSS
GHGVSLAGNELALVPMEPSRSTVTIAGGPTSSNGYSTRSRSNVSPGLIFSTNVENGGHDR
LGSLSKKEKGGLAGLQNLGNTCFMNSALQCLVHTPPLVDYFLQDYVNEINKQNPLGMHGE
LAIAFGNLLREVWSSGQTLITPRPFKGKLARFAPQFSGYNQHDSQELLAFLLDGLHEDLN
RVKQKPYIEMKDADGRPDDEYAEECWKNHKARNDSIIVDFYQGQYKSTLVCPVCNKISIT
FDPFMYLSLPLPSMINRTMTVTVLYGNGNGLPMPYTVTVSKHGCCRDLIQALGTACCLKN
DESLLLAEVYDHKIYRYFETALETLSSIKDDEHIVAYRVPKKLTGLKRLEIVHQSPEKKR
LGSPLVTYMHEEPQNVADVCTAITTILSPLKKAVVSSNRNHNEKNNGSASSANNEADNGL
MDNTADDSNFPFQLTVTEDNLSSGKIIDDDYVKNSPLLKVTLHWTDSELDNYDISYLENL
PDVYKSGFSAKKTRQEAVSLFSCLDAFLKEEPLGPDDMWYCPNCKEHRQASKKLDLWRLP
DILVFHLKRFSYSRYFKNKLDTFVSFPIQNLDLGKYANKEASNGPYVYELYAISNHYGGL
GGGHYSAYAKLIDEDRWYHFDDSHVSPVSESEIKTSAAYVLFYRKVKVEANYEAR
>Sgl52494 E3_adaptor/Cullin_RING/DCX/DWD 39 0.5
MASKIQEARRKFKNRERKVAANASMEKSGDEMLLTPKQIEELLKLIPSATKKTDPESEDE
LADSFAFAGMAKCCSVLNKNEKWILDSGASDHMVCDVRYLEKPVKIKHKININLPTGKKV
EISHMGEVNLGKGIKLKDVLYVPAFEHNLVSMSKLTQEGKYNVIFNDRKCLLQDCLPGKT
DELGSLREGLYCVDLAVGRKKNEVRSVSKEGYVNQVGSKNVDFKVWHNRLGHVPLSKLKQ
IGCIDPKFSKDDCVCVTCPMAKFAKLPFKLSKSVASKPFHLIHIDIWGPYKVCTGGKFNY
FLTIVDDYSRCVWVYLMKQKSDAFSVIQKFGNFVKNQFDSKIKVIRSDNALEFKDKNCNA
YFDQEGIVHETSCVDRPQQNGRVERKHRNILEMSRALRMQAGLPLKYWGDCVLTAVYITN
RVPSLVIGNKTPYEKLFNKQPDYSHLRSFGCLVFASNPSVKRDKFGVKGVPCVFLGYPAH
TKGYKLLNLLTNQSFVSRDVKFYEHIFPCNKNAESQYLQPMPVQMTNLQEIQEEWCEDDC
ETDSQESGNSDTQDAEPEAVATSETEAIVAESEIRRSSRQLKSPTWLKDYVTDSKGTQAL
NVATSKVCGLKWSYDNRELASGGNDNRLFVWNQHSTQPILKYYEHTAAVKAIAWSPHLHG
LLASGGGTADRCIRFWNTTTNSQLGCVDTGSQDVDYEATITTKLSIAKKIFTLEKDLIPL
IYL
>Sgl52503 UBD/SH3 41.7 0.0
MVCNSLRTLVRSAELEDARLLVRRYDKLWNEVETQAAEVLKLRSKATEGAKSEENFAKLE
LAEDKLDDLKSRLMALGKEATSAMLSVEAHQQNMTFQQLVVMLSAERYYHQNVLSTLEKL
LPEMLRLEQMSELVLPEDATQNQLHALETERNPDSNGSKEHEDDAYVAKVVHPFDAEAEG
ELTLLIGDIVVVQQSILGGWSKGECNGKTGWFPSPYVQRLDEVSEGNVKWANL
>Sgl52544 E3_adaptor/Cullin_RING/DCX/DWD 95.3 10.1
MEEEVIMASSSMDGGVGCWELKSGNEKLRYKSCLSPPHSLISVGSRFFASSQLRASSSSG
SILYWSWHKPQPEVKSFPAEPIKPLVSNREGSYIIGGGASGNIYVWEVFTGRLLKKWYAH
NGAISCLTLSDDESLLISGAEDGGVKVWSLFMMFSDDRRKKARNDHVHSFRDHTLRVTDV
KSGHGGSNVVIISASEDHTCKVWSLATGKLLRNIIFPSVIDAIAIDVGEYAFYAGGRDGK
IYITALNASTTCSTDYGKHIIGSLANSSRAVTSLAFCADGISLVSGSEDGNIRIWDISTR
NIVRMFRHSKGPVTNVLVTCVSETMKSQALAGRKTLFIPPSLEKYANSSEEVVGSKVFIG
CDSMSDSATVSYLTEHVLNNQIKEIQQKGSTAAAEMEVERLKLESKRAMQMVEQWKKMYD
NLHQFCVNEIVDDSEAKLSCVNSG
>Sgl52594 E3_activity/RING/RING 18.9 4.5
MECLHRFCRECIDKSMRMGNNECPACRTHYASRRSLRDDQRFGQLIAVLYPDIRKFEEEV
MYELEDVDLQKICYEVPPKRKEKEMAFYDEDEARNKQIQESITQVLIKQSEALGKKCSSN
KDAAGPSVTRSQR
>Sgl52609 E3_adaptor/Cullin_RING/SCF/F-box 13.8 0.0
MLSCKRLLFNSNKRKNMKKKKKNRANLTNNQKKNRANSINNQPSFDTAEEHEDEEANVFS
LRNSINHGVQPLGNFFLSSTSQNSRDIGLGNFKVVSDELVLEILGILDVNSLGILATVSK
SFYVFCTHEPLWRNLVLETLKGGFLFNGSWRKTYIAANFPCFDVSNVGFCGLSIKEFYSD
YLFQSWLCANLEMKPEWLQRDNIPRRKGISVEEFILKFEEPNKPVLLEGCLDNWVAKDVW
DKDYLIKTCGDVKFSVGPVEMKLEDYFRYSELTREERPLYLFDPKFAEKVPSLGKEYEVP
VYFKEDLFSVLGEERPDYRWIIIGPAGSGSSFHIDPNSTSAWNAVIKGSKKWVLFPPEVV
PPGVHPSPDGAEVACPVSIIEWFMNFYGATKDWKKRPIECVCKAGEVIFVPNGWWHLVIN
LEESIAITQNYVSRRNLLNVLEFLQKPNASELVSGTRDRVNLHNKFKKAIDAAFPGTIDQ
LVTKAEEQKKILSYWETVADSHTGGFKFSF
>Sgl52637 E3_adaptor/Cullin_RING/DCX/DWD 15.7 0.1
MKVYNLFEEETPQIFALCGQGPRSSLRILRPGLGVSDMATSPLPGVPNGIWTVKRNVKDE
FDAYIVVSFASATLVLSIGETVEEVSDSGFLDTTASLAVSLIGDDSLMQVHPSGIRHIRE
DGRINEWRTPGKKMITKVGYNRLQAVIALSGGELLYFEVDMTGQLMEVEKHEMPGDIACL
DIAPIPDGRKRSRFLAVGSYDNCIRILSLDPDDCLQVLSLQSVYSPPESLLFLEIQASTG
GEDGADHPANLFLNAGLQNGVLFRTVVDMVTGQLSDSRSRFLGLRAPKLFAVNVRGRRAM
LCLSSRTWIGYMYQGNFFLTPLTHGILEFAATFSSDNCAEGIVAVAAEALTVFTIDKLGE
TFDQTVFPLRYTPRKFVLQPKRKLLVILESDQRAFKAEEREAAQNECFQTGMDDNGNLRM
EYVDDNEFSDEQYGYPKAEVQQWVSCIRVLDPRTGESISCLELEDNEAALSICNVTFNDK
ECGTLLAVGTAKSLQFFPKKSFDAAYIHIYRFVDGGKLELLHKTQVDGVPLALSQFQGRL
LAGIGTVLRLYDLGKKRLLRKCENKLFPSTIISLHTYRDRIYVGDIQESFHYCKYRRDEN
QIYVFADDFYPRWLTASQHVDFDTMAGADKFGNVFFVRLPQDVSDDIEEDPTGGKIKWEQ
CKLNGAPNKLEEIVQFHVGDIVSSLQKASLTPGGVECVLYGTVMGSLGAFLPFSSRDDVD
FFSHLEMHMRQEHPPLCGRDHMAYRSAYFPVKDVIDGDLCEQFPTLPVELQKKIAEELDR
SPAEILKKLEEIRNKII
>Sgl52638 E3_adaptor/Cullin_RING/DCX/DWD 13.3 0.1
MYLYNLTLEKPTGIVTAINGNFSGSSKQEIVVGRGKVLDLISPDENGKLQTLVSVEIFGA
IRSLSQFRFTGSSKDYIVVGSDSGRIVILDYNKVTNSFDKIHQETFGKSGCRRIVPGQYL
GVDPKGRAVMISACEKQKLVYVLNRDSSARLTISSPLEAHKSHTLTYSICGVDCGFDNPV
FAAIEVDYSEFDQDSTGLSVAQAQKHLTFYELDLGLNHVSRKWSEPIDNGANMLITVPGG
GDGPSGVLVCAENFLIYKNQGCSDVRVLIPRREDLPAERGVIIVSVARHKSLSFILVQTE
YGDIFKVTLEHGEEGVSELKIKYFDTIPVTSSMCVLKPGYLFAASEFGDHALYQFQGTGD
EPDVESLLCYNDGLGNRRRLPASVL
>Sgl52644 E3_adaptor/Cullin_RING/DCX/DWD 25.7 1.0
MYLYNLTLEKPTGIVTAINGNFSGSSKQEIVVGRGKVLDLISPDENGKLQTLVSVEIFGA
IRSLSQFRFTGSSKDYIVVGSDSGRIVILDYNKVTNSFDKIHQETFGKSGCRRIVPGQYL
GVDPKGRAVMISACEKQKLVYVLNRDSSARLTISSPLEAHKSHTLTYSICGVDCGFDNPV
FAAIEVDYSEFDQDSTGLSVAQAQKHLTFYELDLGLNHVSRKWSEPIDNGANMLITVPGG
GDGPSGVLVCAENFLIYKNQGCSDVRVLIPRREDLPAERGVIIVSVARHKSLSFILVQTE
YGDIFKVTLEHGEEGVSELKIKYFDTIPVTSSMCVLKPGYLFAASEFGDHALYQFQGTGD
EPDVESSSATMMDLETDEGFRPVFFKPRKLKNLIRVDQVQSLMPIIDMKVYNLFEEETPQ
IFALCGQGPRSSLRILRPGLGVSDMATSPLPGVPNGIWTVKRNVKDEFDAYIVVSFASAT
LVLSIGETVEEVSDSGFLDTTASLAVSLIGDDSLMQVHPSGIRHIREDGRINEWRTPGKK
MITKVGYNRLQAVIALSGGELLYFEVDMTGQLMEVEKHEMPGDIACLDIAPIPDGRKRSR
FLAVGSYDNCIRILSLDPDDCLQVLSLQSVYSPPESLLFLEIQASTGGEDGADHPANLFL
NAGLQNGVLFRTVVDMVTGQLSDSRSRFLGLRAPKLFAVNVRGRRAMLCLSSRTWIGYMY
QGNFFLTPLTHGILEFAATFSSDNCAEGIVAVAAEALTVFTIDKLGETFDQTVFPLRYTP
RKFVLQPKRKLLVILESDQRAFKAEEREAAQNECFQTGMDDNGNLRMEYVDDNEFSDEQY
GYPKAEVQQWVSCIRVLDPRTGESISCLELEDNEAALSICNVTFNDKECGTLLAVGTAKS
LQFFPKKSFDAAYIHIYRFVDGGKLELLHKTQVDGVPLALSQFQGRLLAGIGTVLRLYDL
GKKRLLRKCENKLFPSTIISLHTYRDRIYVGDIQEALTLLYLNSMSLNS
>Sgl52662 E3_adaptor/Cullin_RING/DCX/DWD 23.6 1.0
MYLYNLTLEKPTGIVTAINGNFSGSSKQEIVVGRGKVLDLISPDENGKLQTLVSVEIFGA
IRSLSQFRFTGSSKDYIVVGSDSGRIVILDYNKVTNSFDKIHQETFGKSGCRRIVPGQYL
GVDPKGRAVMISACEKQNLFYWFICGSSSKHLTFYELDLGLNHVSRKWSEPIDNGANMLI
TVPGGGDGPSGVLVCAENFLIYKNQGCSDVRVLIPRREDLPAERGVIIVSVARHKSLSFI
LVQTEYGDIFKVTLEHGEEGVSELKIKYFDTIPVTSSMCVLKPGDEPDVESSSATMMDLE
TDEGFRPVFFKPRKLKNLIRVDQVQSLMPIIDMKVYNLFEEETPQIFALCGQGPRSSLRI
LRPGLGVSEMATSPLPGVPNGIWTVKRNVKDEFDAYIVVSFASATLVLSIGETVEEVSDS
GFLDTTASLAVSLIGDDSLMQVHPSGIRHIREDGRINEWRTPGKKMITKVGYNRLQAVIA
LSGGELLYFEVDMTDGRKRSRFLAVGSYDNCIRILSLDPDDCLQVLSLQSVYSPPESLLF
LEIQASTGGEDGADHPANLFLNAGLQNGVLFRTVVDMVTGQLSDSRSRFLGLRAPKLFAV
NVRGRRAMLCLSSRTWIGYMYQGNFFLTPLTHGILEFAATFSSDNCAEGIVAVAAEALTV
FTIDKLGETFDQTVFPLRYTPRKFVLQPKRKLLVIVESDQRAFKAEEREAAQNECFQAGM
DDNGNLRMEYVDDNEFSDEQYGYPKAEVQQWVSCIRVLDPRTGESISCLELEDNEAALSI
YGVPLALSQFQGRLLAGIGTVLRLYDLGKKRLLRKCENKLFPSTIISLHTYRDRIYVGDI
QESFHYCKYRRDENQIYVFADDFYPRWLTASQHVDFDTMAGADKFGNVFFVRLPQDVSDD
IEEDPTGGKIKWEQCKLNGAPNKLEEIVQFHVGDIVSSLQKASLTPGGVECVLYGTVMGS
LGAFLPFSSRDDVDFFSHLEMHMRQEHPPLCGRDHMAYRSAYFPVKDVIDGDLCEQFPTL
PVELQKKIAEELDRSPAEILKKLEEIRNKII
>Sgl52695 DUB/USP 239.2 2.1
MTMMTQPALDQEDEEMLVPHSDVVVEGPQPMEAVAQADANSVADNQAVEEPPTSKFTWTI
EGFSKLNVKKHYSDVFVVGGYKWRILIFPKGNNVDYLSMYLDVADAPALPYGWSRYAAFS
LLVVNQAQHKYSIRKETQHQFNARESDWGFTSFMSLSDVYDPSRGYLLNDTLIIEAEVAV
RRVMDYWSYDSKKETGFVGLKNQGATCYMNSLLQTLYHIPYFRKAVYHMPTTENDNPTNS
IPLALQSLFYKLQYNDTSVSTKELTKSFGWDTYDSFMQHDVQELNRVLSEKLEDKMKGTV
VEGTIQKLFEGHHMNYIECVNVDYKSTRKESFYDLQLDVKGCRDVYASFDKYVEVERLEG
DNKYHAENHGLQDAKKGVLFLDFPPVLQLQLKRFEYDFMRDTMVKINDRYEFPLQLDLDR
ENGKYLAPGADRSVRNLYTLHSVLVHSGGVHGGHYYAFIRPTLTDQWFKFDDERVTKEDV
KRALEEQYGGEEELPQTNPGFNNAPFKFTKYSNAYMLVYIRESDKDKVVCNVDEKDIAEH
LRTRLKKEQEEKEDKRRYKAQAHLYTIIKVARDDDLVEQIGRDIYFDLVDHDKVRSFRVQ
KQMTFNVFKEEVAKEFGIPVQFQRYWIWAKRQNHTYRPNRPLTPAEEAQTVGQLREASNK
MHSAELKLFLEIEIGLDLHPIAPPDKTKEEILLFFKLYDPEKEELRYVGRIFVKSAGKPS
EILSKLNELAGFAVDEEIELYEEIKFEPCVMCEHLDKRVSFKLSQLEDGDIICFQKVPSA
DSEERYRYPDVPSFLEYVHNRQVVHFRSLERPKEDDFSLELSKINTYDEVVERVAQRLGL
DDPSKIRLTSHNCYSQQPKPQPIKYRGVDHLSDMLIHYNQNKKDEWTCKSSDILYYEVLD
IPLPELQGLKNLKVAFHPATKDEVAIHNIRLPKQSTVGDVIDELKTKVELSHPDVELRLL
EVFYHKIYKIFPSSEKIENINDQYWTLRAEEVPEEEKNLELNDRLIHVYHFTKDTTQNQL
QVQNFGEPFFLVIREGETLAEIKVRIQKRLHVPDDEFSKWKFAFMSLGRPEYLDDSDIVS
SRFQRRDVYGAWEQYLGMEHTDTTPKRAYSANQNRHTFEKPVKIYN
>Sgl52722 UBD/Alpha-Helix/UBA 29.2 0.1
MRPNIVSEASVTTRLNQWWEGIPFITSAVVAVCAAIYLVCLLFGYDSFVEICFLPSAIVS
QFQVYRIYTSILFHGSFLHVFFNMLALVPMGSELERIMGSVRLLYTTLLLALSNAVFHLS
IAFMVAHNPFHPYPYLMAECAIGFSGVLFSMIVIQTSLSGAQSQSVFGLFNVPTKWYPWI
LLVVFQLLMTNVSLLGHLCGILSGFAYTYGLFNLIIPGTSFFSGIESSSWLSACVRRPKF
ILCTGGNPSGYIPTYTNPNSTSSGSVTNLWSHLTSLMPQRDTSSQNVQSTQDNRFPGRGR
TLAAPRSETAPSVTPDSNLQTRLLDDTGSNEQSDMRAINSGGGRSPAVNSATEPTSSPQQ
QALVVSAEDSQRLVAMGFDKTQVEVALAAADGDLDVAVEILMTQQV
>Sgl52928 UBD/UBC-like/UBD_UBC 67.5 0.0
MEKTKAQEVLIVSRKQVTKTLQETRAIWILLTKELADEGIKLISNINNPALQQLVRKYED
VFPAELPPGLPPLRGIEHQIDLIPGASELAADLKQAKPKFDAAGVELIAVGVGTADKARL
LGERNVKADSEKIQKSMNLEHEPVEKVKKSLPRAYSRIDSEKDLTSQMGLSPYKGGAWKI
MVELPNAYPYKSPSIGFVNKIFHPNVDEMSASVCLYVINQTWIPMFDLVKVFDVFLPQLL
LYPNSSDPLNGEAAALMMRDKVAYEQRVKGSGVTAQWLKFDNSYFKVLHLLPLNPKVYSF
SNLA
>Sgl53099 ULD/UDP/UBQ/UBQ_Other 23.8 0.0
MVMIRVRSRDGVERLSIDNPNTTTISQLKTLIESQLHVPISNQTLSLNQNLLLAKTPSDR
SQFCDMANPQTLISSLNITHGSLIFMYYDGEREIVAPSRRPTITPAGSFGKKMTMDDLIA
KQMRVTRQESPNCALVSFDRDAANAFQHYVNETLAFGVKRGGIMYGTVSEDGRVEVDFIY
EPPQAGQEERLVLMRNKDEEKIVDAIANGLGMRKVGFIFTQAVGQDKKDYTMSSLEVAQA
IELHAESELKEWVTALVKLKVNEDGGADVHFEAFQMSDMSVRLFKEGWFDFECKEGEEID
PKVSRMKKDVVVGGKDVREVDNDFFLVVVKIFDHQGPLSSTFPIENRMVPVTTKAVKTHL
ERTKSLPFVKRISDFHLLLTLGRFFDLNADIPALTECVHSQSSVPEGYQLLIESIANAGV
>Sgl53128 UBD/UBC-like/UBD_UEV 173 0.1
MAPLQPHSQSQSIHSNPQILQFLSNVLSQRGPSSLPYSEDVKWLIRQHLVSLTDAFPSLQ
PKTATFTHNDGRTVNLLQADGTVPMSYGGVTYNIPVVIWLMELYPRHPPCVFVNPTRDMI
IKRPHPHVSPSGLVSIPCLHKWVYPSSNLVDLARDLSVFFGRDPPLYSQRKPDSPSNNPN
PNPTVSTYSNHSHSHSFGGDSSNSASSGSIGHPPRVFPPSPYVGSGRIMPQRPSGGTDDP
NEVFKRNAINKLVEMVHGDVVGLRKTREADMEGMFSAQATLRQREEKISNGLKNMLDEKE
GLEQQLQLVLTNADVLEAWLKENEEKMSKLGDNVDVDDAFEPCDSISKQIIEASASDLAI
EDVIYALDKAVQDGVIPFDQYLKNVRLLAREQFFHRATSMKVRAAQMQAYVASMASRTAQ
HMM
>Sgl53322 E3_activity/RING/RING 19 4.5
MECLHRFCRECIDKSMRMGNNECPACRTHCASRRSLRDDQRFDQLIAVLYPDIRKFEEEV
MYELEDVDLQKICYEVPPKRKKKEVAFYDEDEARNKQIKESITQVLIKQSEALGKKRSSN
KDAVGPSVTRSQR
>Sgl53358 E3_activity/RING/RING 35.7 6.5
MNKYPLITFTLLYICFLLPQLKAVELCSSFSCNRHRHDPIMFPFRVPDNQSTRCGYPGFE
LSCNNSNDQTLLSLSSEPLVVEAIQYMYQLILLSDPNHCIPKRVMDLGLQPTPYSFGRRA
SPYTFLNCSKTNNNVTLVDDLPKGSSVISCMSDGNDTVVATFNNRAEEEMVGRRGCTVMK
RLNAAFWWRDMEYGYEEVDLSDALVELSWGVPDCRECYGRGGSCGLVGGSGLEVGCLLPD
SSDFPKGAKYGLILGAGIPALLCIIGLIIYIGSRIRIARNRHHHHTNTGSSPSIFPQPIV
LTLGLDQPTIESYPKTVLGESKRLPKPSDNTCPICLSEYQPKESLRTIPECKHYFHADCI
DEWLRMNATCPLCRNSPDRSSTLPNC
>Sgl53733 UBD/UBC-like/UBD_UBC 177.6 0.0
MVDFARVQKELKECNKEMNVSGISVKIKDDSLSHLIGTIPGPVDSPYEGGSFLIDIVLTD
GYPFEPPKMKFLTKVWHPNISSQSGAICLDILKDQWSPALTLKTALVSIQALLSAPEPDD
PQDAVVAKQYLKEYQTFVGTARHWTEAFAKTSSHGIEEKVQRLVEMGFPEAQVRSALEVV
GGDENLALEKLCSS
>Sgl53748 ULD/UDP/UBQ/UBQ_Other 40.9 0.0
MPEEDLVDIKFRVYDGSDIGPFRYSSASTIEMLKERIVSEWPKGKTVVPKAATEIKLIYF
GKVLENNKTVGQSRAPFGELTGGVMVMHVVVQPSQAKTKSEKKIEESKKFVCSCCIM
>Sgl53780 E3_adaptor/Cullin_RING/DCX/DWD 109.3 33.4
MAPIFEYFIVCGIGAEIRTLDEYKGFYGTNYRYLPSLLDQYPPSNQSPSPPPPPQLPTCV
LPAGVEFYASGFDRNDPSTYPRTYPIVLTEGDGSKIYVTCIAFRDPVDEDIVDAHHIPLN
SLADKCICLVSRLPSFHVLRYALEEIFALCFSPSGSCKPLWDVIAYMVSNVPLPTPGKDR
VLFAIENSLLCVEAPPKDGLPHADISFQPLVQCLDVDNLLKLFTAVLLERRILLRSNKYS
LLTLVSEAICHLIYPFRWQHVYIPLLFFSGVDYIDAPTPYMMGLHSGVDTTGLSMDGVVI
VDLESNRITTSEEIPPIPEPELSSLRGDILKLLYPNVVDIDLMKSGLRKSFDLYHRVANR
PWSEEHDAQLRMIFLKFLASILSGYRNFIENSATNIFNTQAFLKKRSRLTNQPQDEMIFQ
FLETQGFLDFLERGLGSDYNNSNLLDKLQDAIGRGQDYMSILPSPVLDPEIITISDLGGG
IPASGARYTYERFPSNIRTEEQEEKRKQILAAVSGAQDNPAKATLDHAESLSPRERAAER
ERMVLDIKVKLQGLWLRLLKLGTTDDPLSSFEYGTILALIESDADGVGGSGFVECIREHI
HTGWTCQLTEEQFIAVKELLKTAINLATSRNDMSTVRDALEVSAEIYKKDSNNVSDCVQR
HLISLSIWEELRFWEGYFEYLMDQTSNKPSNYATLVMTQLVVVASHMAGLGLPDTDAWLI
IETIAEKNNIGYKQFIQLRGFLSHIHQLRYAYWGIAASKVQSLSSYGVQSALPQDGVHDS
QQTTEASSGRSWVQSMFSRDSSLRAQSFTRVRSGLSASDENKQDLANATGQKRPQTNVRI
LRGHNGAVTALHCVTRKEVWDLVGDREDAGFFISGSTDCLVKIWDPSLRGSELRATLQGH
TGTVRAISSDRGKIVSGSDDQVILVWDKQTYQLREELKGHTAPISSVRMLSGERVLTSSH
DGTLKMWDVRTDACVATVGRCSSAILCMDYDDSTGVLAAAGRDSVAYLWDIRAGRQIHKL
LGHTKWIRSIRMVGDTLITGSDDWTARMWSVSRGTCDAVLACHAGPVQCVEYSPLEKGII
SGSTDGMLRFWENTDGGIRCVKNVTIHSAPILSINAGEHWLGIGAADNSMSLFQRPQERL
GGLSSSGSKVTGWQLYRTPQKSSAVVRCVASDLERKRVCSGGRNGFLRLWDVTINI
>Sgl53785 E3_adaptor/Cullin_RING/DCX/DWD 111.6 25.9
MARLFDYFVVCGIGPEIRSLDGRSGYFGMDLAYEASLIDQYPPLSHSSYAPLPPELPMCV
MPAGVEFQRSGFEANDPSSYPRSYPIVLTAGDGAKIYVSCIAFRDPVDEDISEAYGIPLN
SFAGKCISLVSRIPCFCVLRDALEEIFALCFSARGSCKPIWEVITATISNVPLPTPGIDR
VLFSIDNCLFSAEAPPENGLPHADISFEPLVQCLDAHNIIFLFTALLLERRILLRSDKYT
LLTLVSEAICHLIYPFQWQNVYIPILFSKGVDYVDAPTPYIIGLHSSVDTSGLSMDGVII
VDIDHNCISTSEEIPPVPEPELSLIHGEIRKLLYPNVMHIDDVYSGIGELYMRCPKDAVK
PWGKDHDLQLRLIFLKFFASTLSGYRNFIVDNAEYSFDAQAFLIHRCRSNNQEPDSMITE
FLASQGLSNYIERIVSSGESNDNVLDKLIDAIGRGESAMSVIPSPHTDLNIVTIPDPTDG
ILDSHAKYMYVKFPANMRSEEDEEKRKQILQYIKDKDDEEKGMIMDIKVKLQGLWTSLLK
LGDAEIILSSDEYETILALVETDAKGIVGRTLIECIREHMRAGWNGQLSMEQFIAVKELI
KGLITCATYQNDIPTLRDALEISAEMYKKDFNDVADYMQRHLLSLPIWEDLGFWEAFFES
LMDQSSLKPSSNERFIMSQLIMMASHMGGLGMPDADAWPIMQDIAQKNNVSYEHYIQLRG
FFSYIYQLQMVYWGISDLKAQSMSSITQSPHFEDAIVDSQQPAKPSTVAKNWVRNMFGRE
SVLKPNSFYRARGWAFDTETTAANEIGTPRKQRKVQTNVRVLRGHRSAITALHCITRRDG
WDVVGDREDMGFFISGSTDCSVKIWDPSHRGSELRATLRGHTGAVRAISSDQRKVVSGSD
DLSIVVWDKHEFLPLEELKGHEAQISYVRMLSGERVLSSAHDGKVKMWDARNGSCIATVA
RCPGAVLCTEYDDTTGILAAAGRDSVVHIWDIRAGKLMHKLSGHKKWIRSIRMAGDTVIT
GSNDWTARLWSISRGSCDAILASHGGSVLAVEYSSLDGGIITGSDDGSVRFWDNTAYNIK
CDKDMKLNSPILSINAEQQWLGVGAADNSMLLFHQSREDTSGRWQLYRTPQFSATTVRCV
ASDLERKRICSGGRDGRLRLWDATVNI
>Sgl53925 E3_activity/RING/RING 37.3 5.1
MASDSSIAEHLKWRKPKIHNHPKHSTTPSSDPNPQMPSIIQSTGCKSTISSLLLSTFTNN
ENPHNSKNKPPRKSSSLRALGCASSQPQVTVPNVIRSSAVWEENNKDKKKNKKKKNKNKK
KMMMINQQQLQGVLMDEQIGVQDLWCADSSAANDSVDCVRPRSARGKIDLDKLHQRERAS
YTSRQRVNNEQFSGLEMDSAFDVPSFGPDVFEARYYNNLRNRSPEGLAEILMFQNGILSN
RRSGADKYRDLRLDVDNMSYEELLELGDRIGHVSTGLGEDQIGRCLRKTKLSVLHELPPH
PHMSSGIEGKCSICQEEYEAEDEVAKLECEHAYHLHCIEQWLVRKNACPVCKAEASSP
>Sgl53978 E3_adaptor/Cullin_RING/DCX/DWD 151.2 21.5
MGEQLQLRGTMRAHTDMVTAIATPIDNSDMIVTASRDKSIILWKLTKEDKTYGVPSRRLT
GHSHFVEDVVLSSDGQFALSGSWDGELRLWDLAAGTTARRFVGHTKDVLSVAFSIDNRQI
VSASRDRTIKLWNTLGECKYTIQEGDGHTDWVSCVRFSPNNLQPTIVSSSWDKTVKIWNL
TNCKLRSTLAGHSGYVNTVAVSPDGSLCASGGKDGVILLWDLAEGKKLYSLDAGTIIHSL
CFSPNRYWLCAATESGIKIWDLESKSIVEDLKVDLKTEADHLEGATTTASKKKVIYCTSL
SWSADGQTLFSGYTDGVIRVYGIARY
>Sgl54007 UBD/Alpha-Helix/UIM 12.9 0.6
MESSCNGGLLYHEVQESKLCAVHCVNTVLQGPFFSEFDLAALAADLDGKERQMMMENRAS
VGDFRSDESHNVSLGGDFSIQVLQKALEVWDLQVIPLNSPVAEPAQIDPELESAFICHLQ
DHWFSIRKVNGEWYNFDSLYAAPEHLSKFYLSAYLDSLKGAGWSIFLVRGNFPTECTLPS
SEASNGYGQWLTPEDCVRILKSCNSKGESSLAIDRTPNQPTDQFASLSEAELLAMEDEDL
KAAIAASLQDSAPAIPVSESGAPSTEKSS
>Sgl54059 E3_activity/RING/RING 30.5 5.6
MNSTGSTYWCHRCDRFIRVHTQHIAICSDCGGGFVEAIDGSSISPLSPISSTTPTRLVPT
NFEDSRSISTSSSPSFNPVIALSRSPEGISFPNYQLFYDDVNDNGIDNDDESRLGFRPLP
VNVAEFVMGSGFDQVLSQLGQLDLNGGFSGLDNSPASKAAVESIPFVEIVDAHVDCDSHC
CAVCKEQFEVGTEARELPCKHIYHSDCILPWLLLNNSCPVCRFKLPTDSGNGNGSGNGNR
DLNSEGISIWRLPGGGFAVGRFMGGGRRNAEEGLFPVVYTEMDHNHNGFENIGDLRRISW
PSRGRRSGRRRGWGRAFRSFFGLFNRNRSSSSRLSVEVEASVSHSRFRMGV
>Sgl54107 E3_adaptor/Cullin_RING/DCX/DWD 103.8 9.0
MDLKRKMTMNWDGLLDEDDDFFDTTNRISAVVPMDMLACPYDDSSDEDEFEDPRMSFTSV
SSFKNGGHTRPTTTANVCGPTPPMPAPKSSSSNEEYDIWMAAPTSIEDRRRRLLHGMGLN
SSKELMRIQTMAMSKKFAAASETSLSSHPLPATSNGEDQEHPCETTSPDTKVTDDHNDHD
HSTTTTSSTPSPDSSVYLIRSRSDGDIEPFSMETRRRKEHLIGDVSKQRLTRTLSTLAPF
TRVCKMSYNDGNSCTTSGTTTATTTTTTSCNDKSHDEKNVGSNKECNDNVCKNNDNCNNK
KSAKNGKKGKSNQQKSGEQLGAFFLIKNLDTGKEFVVKEFAEDGMWNRLSEVQTGKQLTL
EEFEKSVGYSPVVKELMRRQNQRRSNSIDSGGAPLTLERKTSVNAYLSKSFRNSKRRGVS
LLKNINKVANSVTGLGGSTPEREPHSVAQAQTQTQTQSQTQTQTQNQAPTPVEQPKGGKS
GASGNNNDWVRVRTQGKAYKELTALRFCQEIQAHQGSIWTIKFNFDGRYLASAGEDKVIH
IWEVQECEIASLKPPEECANSIPVHPMFCPSPDRDTPAIDKKKKGRSGSRRGSIMPDYVQ
LPETVFALSNEPVCTFQGHLDDVLDLSWSRSQLYLLSSSMDKTVRLWDLETKTCLKLFAH
NDYVTCIQFNPINDEYFISGSLDAKVRIWSVPGRRVVDWTDLHEMVTAACYTPDGQGAAV
GSHKGNCRMYTITDGKLNQTIQFDIQNKKKTAPKKITGFEFASDNPNEVLVTSADSRIRI
YDGSEVTQKFRGFRNTSSQISASFSPDGKYVICGSEDSNVYVWKREEPRNNGKTKTLIDT
RSYEHFQCKDVSVAIPWPGSIKFDPPTIQLHAKKNTKKPAATSSSSATNSPRKDEVNKNN
KRQHLPPLPNNKKNTNVTDKSNNKDNNNNNESQTNVNNNKDEENDKSNISNNNNTNEGNL
EGEKAPESPEADPAQISRTDSGIGDSFSSSAGASLRYDDSPSITSNHASSPSWAPGWSWF
DGGASHGSDTMQARAWGLVIVTAGLGGEIKAYQNIGLPLKVGRQSNLFLA
>Sgl54127 E3_adaptor/Cullin_RING/DCX/DWD 71.1 5.0
MRPILMKGHERPLTFLKYNRDGDLLFSCAKDHNPTVWFADNGERLGTFRGHNGAVWSCDV
SWDSSRLLTGSADTTVKLWDVKKGEQLFTFNFDSPARSVDFSVGDKLAVMTTDPFMEKTS
AIHIKHIAEDIEDQDKESALVIRGPTGRINRAVWGPLNETIISCGEDAIIRVWDPVTGQE
IMSTKDNKSGHKQAITSLSMSADKAQFLTGALDKSAKLWDTRTLTLIKTYVTERPVNAVT
MSPLLDHVVLGGGQEASSVTTSDPRAGKFEAKFYDKVNCSAF
>Sgl54133 E3_adaptor/Cullin_RING/DCX/DWD 88.5 6.7
MRPILMKGHERPLTFLKYNRDGDLLFSCAKDHNPTVWFADNGERLGTFRGHNGAVWSCDV
SWDSSRLLTGSADTTVKLWDVKKGEQLFTFNFDSPARSVDFSVGDKLAVMTTDPFMEKTS
AIHIKHIAEDIEDQDKESALVIRGPTGRINRAVWGPLNETIISCGEDAIIRVWDPVTGQE
IMSTKDNKSGHKQAITSLSMSADKAQFLTGALDKSAKLWDTRTLTLIKTYVTERPVNAVT
MSPLLDHVVLGGGQEASSVTTSDPRAGKFEAKFYDKILEEEIGSVKGHFGPINALAFNPD
GRSFASGGEDGYVRLHHFDTDYFNIKL
>Sgl54247 E3_adaptor/Cullin_RING/BCR/BTB 26.5 0.0
MRTFFHSESCKEPHLNVLNPQSWLQVERGKVSKVAAQASSSIGSLIKVPEPPIVPHFKPV
DYVQVLAQIHEEFESCPPNERSSLYLIQFQVFRGLGEVKLMRRSLRNAWLKASSVHEKII
FGSWLKYEKKGEEFIFDLLGSCSKCAKEFGPIDVASELQDDCSSPLSENASISGSEGIET
VFFRIGSERVRCDRQKMACLSAPFSAMLNGCFTESLCQEIDFSENNISAIGMRAISDFSR
NGCLDDLSPELLVELLVFANKFCCENLKDACDRKLASLVSCRQDAVDLLECAIEENSPIL
AASCLQVFLHDLPDCLNDERVVEILGNANGEQLSVVVGQAAFSLFCLLSEVSMSLDASSD
TTVLFLERLVQSAKNNRQNMIAFHQLGCVRFLRKEFDEAEQLFQKAVREGHTYSIAGLAR
ICYNKNQKSVAFEKLNALILTSSPLGWMYQERSLYYEGDKRWDDLEKATELDPTLTYPYM
YRAASLMRREEAEAAIAEINRILGFKLALECLELRFCFYLALENYEAAFCDVQAILTLSP
GYQMFEGRVAATKLRMLVREHVEKWTTADCWLKLYDRWSSVDDIGSLSVIYQMLESDAAK
GVLYFRQSLLLLRLNCPEAAMRSLQLARQHASSEDERLVYEGWILYDTGHCEEGLCKAEE
SIKLKRSFEAFFLKAYALADSSQDPSCSSAVISLLEDALKCPSDRLRKGQALNNLGSVYV
DCGKFDLAADCYVNALKIRHTRAHQGLARVHFLRNDKTAAYEEMTKLIEKAQNNASAYEK
RSEYCDRELTKADLEMVTRLDPLRVYPYRYRAAVLMDSHKEKEAIEELSRAIAFKADVHL
LHLRAAFHEHIGDVMGALRDCRAALSVDPNHQEMLELHSRVNSHEP
>Sgl54271 E3_adaptor/Cullin_RING/DCX/DWD 35 14.9
MKWTTLLKDLKEKVGLTQQQQSSSSSSLASSSAFPSSSAPSLSSLAVLRGDYNDAPYSTP
DYHRTYLNNTRDKHELEMDFKRFWEDFRSSSSEKEKEAALNMAVDAFCKLAKQYADVAQL
VTMLVEMHIFSFVVGRAFVTDIEKLKISNKMRSLVVEEVLRFFSEVTKDGICPGANLLSA
IELLIAGAVDKQSLLDSGILCCLIHLLNSLLGSNGGNVGNTDSDHDRQLECNHMAEAGGL
RARQLEVEGSVVHVMKALASHPCAAQSLIEDDSLQLLFQMVVNGSLHVYMQYRDGLVPLH
SFQLHRHAMQILGLLLVNDNGSTAKYIRKHQLIKALLMAIKDFNPDFGDPSYTIGIVDLL
LECIELSHRPEAGGVKLREDIHNAHGYHFLVQFALTLASMSQKQTDRALHSNSFSEESAT
GDSRAIGNSGNEESIDSEDGKTSNLSPALSRLLDVLVNLAQIGPAEPPAPRSSKSSHVKG
GGHGRSRTPSVDLSTDEIWEKGNGKVKDLEAVQMLQDIFLKAGCTELQAEVLNRMFKIFS
SHIENYKLCQQLRTVPLFILNMAGFPSALQDIILKILEYAVTVVNCIPEQELLSLCCLLQ
QPITSDLKHTILSFFVKLLSFDQQYKKVLREVGVLEVLLDDLKHNKFQSGPDHQNSETNH
LERKSSPTGFQKHMNSKDAIITSPKLMDSGSGKYLLFEVEVTVSIAWDCMVSLLKKAETN
QSSFRSANGVAIVLPLLVSDVHRSGVLRALSCLIMEDVTQVHAEELGVLVEVMKSGMLTS
VSGSQYKLHDDAKCDIFGALWRVLGVNSSAQRVFGEATGFSLLLTTLHSFQSDGEQTDHS
HLIVYVKVLTYLLRVVTAAVCDNPVNRTKLHVIVSSHTFYDLLCESGLLCVDFERQVVHL
LLELALEIVISPFLASGSATSSEKVDSSSFLLTTPSGVVNPTMERVYNAGAIRVVLRSLL
LFTPKVQLEVLELIEKLAHAGPFNQENLTSVGCVELLLEMIHPFLQGSSPLLMHALRIVE
VLGAYRLSTSELRLLVRYVTQLRKKNSSESLVGMMERLILMEDMASESVSLAPFVEMDMS
KVGHSCVQVSLGERSWPPVAGYSFVCWFQYQNFLKSPAKESEHSKVGSKKLSSSGQQQQV
LRLFSVGSVDSGNTFYAELFLQEDGVLKLATSNSSSLSFSGSDLEEGRWHHLAVVHSKPN
ALTGLFQASIAYVYINGKLRYTGKLGYSPSPVGKPLQITIGTPASHARVSELQWKLRSCY
LFEEVLSSGCICFMYILGRGYRGLFQDTDLLRFVPNQACGGDCMSILDSLEADVNSVSGT
QKPDSSVKTGISRTDGSGIVWDLERLGNLSLQLSGRKLIFAFDGTSTEPLRASGTLSLLN
LVDPTSAAASPIGGIPRFGRLHGDVYVCKPCVIGDIIHPIGGMVSVLALVEAAESRDMLR
MALTLLSCALHQNPQNVREMQACRGYHLLSLFLYRRMSLFDMHCLEIFFKIAACEASFSE
PKKLGISHPSLSPASSAPEASFEELSLSKFRDELSSLGSHGDMDDFSAQKDVFSHISELE
TADMPSENTNCIVLSNADMVEHVLLDWTLWVTAQVSIQIALLNFLEHLVSIHWYRYHNLT
VLRRINLVQHLLVTLQRGDVEVPVLEKLVVLLGVILEDGFLASELENVVRFVIMTFDPPQ
LAHRTAVVRESMGKHVIVRNMLLEMLIDLQVTIRSDELLEQWHRVVSSRIITYFLDEAVH
PSSMRWIMTLLGVCLTSSPTFALKFRTSGGYPGLTRVLPSFYDSPDIYYILFCLMFGKPV
YPRLPEVRMLDFHALVPSDGDHSEIKFVELMDSIIAMAKSTFDRLSTQSMLAHETGNLSQ
IGPSLVAELAEENSDMIGELQGEALMHRTYAARLMGGEASAPSAATSILRFMVDLAKMCP
SFANVCRRAEFLENCVDLYFSCVRASYAVKLARELSIKTEEKNIIDFEDTNSSQNTFSSL
PQDQDQSGKTSISGGSFPQGQVSSSSEDIPLAMNGKIVKQEDLSASNKKSEVTLATQEDI
PAVQILDDVTNDKVSMNPSSITDVNVPNVTTMVMSDIPTDTQSSTSIAMPNSPILSERSG
SKLAPTIGPSDVALTSGPHSTTNASFVSSNLTSENDLIVDKKHSPQGSSESSFFVISSKL
LLEIDDSGYGGGPCAAGATAVLDCLAEVLSDVLTEQIKAVPMVERILESVPLYADTEAVL
VFQGLCLSRVMNFLERRLLRDDEENSKKLDKSRWSSNLDVFCGVIVDRIYMGAFPRPAGV
LRTLEFLLSMLQLANKDGRIEEAYSVAKGLLSIGRGTRQLDPYISAILKSTNRMILYCFL
PSFLGTIGEDDLLSSLGIPSFNEKEQTSAYQQEETGIDICTVLQLLDAHVRIVFCPSNVD
AELNCCLCVNLISLLHDQRQNARNMAIDILKYLLVHRRASFEDLLVSKSNRLDVLRGGFD
KLLTGSISSFFEWFQSSQPTVNKVLEQGAGLMWVQSITGSSKFPGLRIKSMDNHRGSEMI
KKSKELAKLDVKHWEQITERRYALELVRDAMSTELRVVRQDKYGWVLHAESEWQTHLQQL
IHERGIFPTRKTPEAGESEWELCPIEGPYRMRKKLDRCKLKVDTIQNVLDSQFDLGQADL
SKEKNENGRDASDSGSDSFSQLLVDGGQQLSLEGELYDEFSVKDCDDVREVSSAREALID
DRASSINESLHSAVEFGTRSSALSGPISDSLQGKSEVESQLMSSSMKTDDIKVAEDRSER
ELLDNGEYLIRPYLEPFEKIRFRYNCERVVGLDKHDGIFLIGELCLYIIENFYIDSSGCI
CEKESEDDLSIIDQALGVKKDVMFMDFQSKSTSSWAATVKTGAGGRAWAYNGGAWGKEKT
CSTGTLPHVWRMWKLNSVHEILKRDYQLRPVAVEIFSMDGCNDLLVFHKKEREEVFKNLV
AMNLPRNSMLDTTISGATKQDSNEGSRLFKLVAKSFSKRWQNGEISNFQYLMHLNTLAGR
GYSDLTQYPVFPWVLADYESEDLDLSNPNTFRKLDKPMGCQTPEGEDEFRKRYESWDDPE
VPKFHYGSHYSSAGIVLFYLLRLPPFSTENQKLQGGQFDHADRLFNSIRDTWSSAAGKGN
TSDVKELIPEFFYMPEFIENRFSLDLGEKQSGEKVGDVVLPPWAKGSAREFIRKHREALE
CDYISENLHHWIDLIFGFKQRGKAAEDAVNVFYHYTYEGSVDIDSVTDPAMKASILAQIN
HFGQTPKQLFVKPHVKRKVDRKPPHPLKHSINLVPHDIRKTSSSITQIVTMNDRILLAGT
NHVLKPRTYAKYIAWGFPDRSLRFMSYDQDKLLSTHENLHGGDQIQCVGVTHDGQSVVTG
ADDGLVSVWRIQKDSSQRVRRLQLEKALCGHSAKVSCLYVSQPYMLVVSGSDDCTVILWD
LSSLAFVRQLPEFPSPISAVYVNDLTGDIITAAGVLLAIWSVNGDCLAVINTSQLPSDFI
LSVATSSSSDWQDTNWFVTGHQSGAVKVWKMVHCTDKESAQSKPTANGTAGLALRKQPEY
KLLLHKVLKSHKHPVTALHMTSDLKQLLSGDSAGHLLSWTLSGDSLRGSSSYG
>Sgl54304 E3_activity/RING/RING 32.3 11.5
MSSDHIIIHQDEELSTSSFIRIIKITPYPVSFGSINKPLERYSVACTIKQTTITVFSSYD
EQGNPTQPGLLVRAHESHPNKSITVNYVPSSEIELEITRFCLRSRLHLSPKNEDALMDMI
HHQININNGFNNVRPNNNNNHNQQEQDVWPDQMHLDVTFHQVDIERRYVSLDQLHGFALS
LKNEECSVCLEELDKNGKTRPLICLCCNHVFHESCIVNWLATSLSCPLCRREVPLEI
>Sgl54306 ULD/UDP/UFD/PB1 70.8 0.0
MARSETYENDLHLEATELRLGLPGSKEPQDVSNNVSKSNKRSSPDQVLEDSSSTNNSSVS
DARNDECPPPSKTQIVGWPPIRSYRKNTLQAKKTESEASGMYVKVSMDGAPYLRKIDLKV
YQSYEELLKALESMFKICIGKYSERDGYNGSDLAPTYEDKDGDWMLVGDVPWEMFTTSCK
RLRVMKSSEAKGLGCL
>Sgl54307 ULD/UDP/UFD/PB1 61.2 0.0
MEVGLKMEDTELSLGLGLGLGLRGGGDKSSDGGGGVVKSNKRGYSETVELKLNNNNNNNC
VAVAKEESATSNPLDLLMKNDNKKNDVSPKEVSSKVVDHAAKPPSKTQVVGWPPVRAYRK
NMLAVQKTTGGQDSESEKLMSGGGGALVKVSMDGAPYLRKVDLKMYKSYQDLSAALGKMF
SSFTLGNYGAQGMIDFMNESKLMDLLNDSDYVPTYEDKDGDWMLVGDVPWEMFVESCKRL
RIMKGKEAAGLAPRAMEKCKNRS
>Sgl54309 E3_adaptor/Cullin_RING/SCF/F-box 13.4 0.2
MRHHIATPSTPATPFVDPTKRPKKRGSYNCGRCGLPKKGHVCDTAAVPTTVSVNPVTPRH
PPPRPQRALSFDNLDVADSFDNEAAVASTAALLDYHHHHNNNDGGGEDDEVYFDGDEIVS
GGLPAICMWEVMTRLPPSSVMSASGVCKGWRDLAGRVWRNTRELRVRVPSHGAVGFVGSL
LKKCCSSLVRISLQMESDVDATLLACIAFSCPNLESLEISTTESSINRITGDELSRFLAD
RRCLTNLKMEGCSNLGSVVVSSSSLSTLWLSDLHSLSKTIFNCPSLREVSLNFSHQENDS
TDIAAMMDNLGKFCPKLQNIHVASPRLSHATVLALTEANLRGLKMLSLVLGSGITDASVA
AIAYSFLKLEHLDLSGSSITDSGIGIICNVFSRTLSRLLLALCPNITSSGIQFATAQLPL
LELMDCGMTICDPNVNEVTGDDSNDYEPPKSSNMHHIYQKLIIKHNQLKKLSLWGCSGLD
ALYLNCPELGDLNLTSCRNLHPERLLLQCPNLESIHAAGCVDSLSRVIETQIENAPLESH
LLIKRMADGSKRVRVPHILSPQPSDDSKQCHVRKRRCIVVKE
>Sgl54324 ULD/UDP/UFD/UBX 43.3 0.0
MNIDSPLAWKRRRLIDIDPMEAEAARAKLEAAKQKYGRELRVLETSTGSQSSPEAANTDE
PDDFFEFTAEDYYVLMGNKKEDKFLKTKKIREAEAAARRSKITKAVVRLRFPDDHILEAT
FHPSEPLQSIYDLLKKVLARPELPHYLYTTPPKKQIKDTRQDFFAAGFIPGAIVHFSYDL
PRDDAAFSGPFLQEDVMSLKGLDLVPETTKEPITETTSETAVVNDRPIVPERKPAEKKAA
KPKWLKM
>Sgl54335 ULD/UDP/UFD/UBX 43.3 0.0
MNIDSPLAWKRRRLIDIDPMEAEAARAKLEAAKQKYGRELRVLETSTGSQSSPEAANTDE
PDDFFEFTAEDYYVLMGNKKEDKFLKTKKIREAEAAARRSKITKAVVRLRFPDDHILEAT
FHPSEPLQSIYDLLKKVLARPELPHYLYTTPPKKQIKDTRQDFFAAGFIPGAIVHFSYDL
PRDDAAFSGPFLQEDVMSLKGLDLVPETTKEPITETTSETAVVNDRPIVPERKPAEKKAA
KPKWLKM
>Sgl54380 E3_adaptor/Cullin_RING/SCF/F-box 12.4 0.1
MANSSSSSMIIPEIDDANHSLIPNLPNDLSSLILSFIPLPFHGRLKSICKSWRKFYSSKT
PFYLRNTHLPSSSLSHLLCVFPQDPSLSSPYLFDPTFLAWAPLPPMPVNPHVYSLSNFAA
LSIGPHVYVLGGSLFDTRAFPMDRPVASSAVFRYDLVVGRWFQLAPMRAPRGSLAAAAVG
RGKIVVAGGGSRHSMFGAAGTRVGSAEVYDVERDEWAQVAGLPGSRAGCVGFYVGRSREF
WVMGGYGEAKTINGVLPVDEHYKDAVVLGLEDGRWREIGDMWDDNERPRLGKVVVINDDD
DKYLPEVFMLDGNDIFRYNMASNRWFKESHVPKKNQDGSPFGFVALHGELHVISHLQGVE
LSAIKRSRHRRRGNALFMQIYNPRKMSWRSLVTRTPFQCPLDFKTAVMCTIRV
>Sgl54410 E3_activity/RING/RING 39 5.6
MDSSLLSQQQQQQQPPPTPHTSNSDFPIAIAVLAILALAILLVSYYIFVTKCCISWHTFD
PLRRFSISRTPRDEGSIISFSPMLGPIHHRGLDEFLLNNIPTMQYKPNNQNFNKNNLGRS
FRGCAVCLNEFEEKEMLRVLPRCNHTFHLDCIDVWLLNNASCPLCRSNISGRTKYPLDHI
IAPSSSPQDLISPMYSGNLSMISFNGDDQDYLVIEIGDEDATQPSSTQRKNEHNTKLMSR
KKLHNFSIMGDECINIGHKDEQFAVQQPIRRSFSMDSAADRGLILQVQEIVRQNHMQLYC
NNNNNNNNEVSSSTSASIHEECNNNNNSVSGRIRRSSFFSFRHGRGRSRSSSILPIECDH
>Sgl54438 E3_activity/RING/RING 9.1 8.7
MLQIRLNKGASLDGSTGAKPLPGETVTVACPDHLVLADLPVAKGLGSATSASMVKIVGRR
SRRQLAERVHFCVRCDFPIAVYGRLSPCEHAFCLDCARSDSICYLCDERIHKIQTIKMME
GIFVCAAPHCLKSFLKKSEFESHIHESHADLLQPNMKKEEMSESEVSGSKQSSTLDTTVR
GPQRSGFPLGSNDRDDKGRRQQPREQPPLRPLMPPKLPPFYGQAHPSDPQPDNRAMGLDG
AGQTRMQQQNVEAQGGTQQDFGQFSDKQQQGLLPDPHREYPQMYPQQPPNFPMPGNGNPM
MMGAPPFGFPPFQSDGAPPFYGASNTYEVARSDSIGEGGSEQGSVLGFAPGPGGPVNYPD
GFPRPWNGGPANVPFEAGQGGQGLMAPPPPPPGPPPPHLMQHKHGYYSGDSSNDGKSYGW
QSERHDGFGSSQD
>Sgl54453 E3_activity/RING/U-box 95.2 0.2
MYHYVINGDVGGIHFLSKQGASLEWKDKEGKTPLMVAAKDPRLYDVSKTLIEMGANVNAF
CKGHKGGTPLHYAATEGLDNTVALLLSHGANAFVKNREHLTPLDVARKNGRNLVVREIES
RVCYFAGHIRESFGPGLSNVAAPQSSSSAVIWVVVVPRSLHNPPTPPKLELVIYSTPQDA
EPRKILSLRRSKIKAPRFDQPSPTLIVFDKQTSTRYKFSSVTINDKQQLRRLYNACKGIS
QVAPTAAQIMISEATNSPLHPSSQISSPAWRTPRIFSPPMTPNNNVWVYESPRRIDYYSN
ANWGVTQLNPATAVPSPTPSAPPVSNSNSNNSIIGNDGVSASVAAADTAVQPPEVSNSAV
CVVCWEARVEAACVPCGHVSTCMPCLKKIKDNNEACPVCRAEIDQIVKLYASPASGEMET
TYMRCLNNSISRFIHLMSCQTSKVIPSQNDFENLAAMLKHLKPVLDEIDDAKIASEEDLW
KECEDLDIYINAARELMERWSSKMSRIVSVSQGEQLLKKIKKSSLEICSILCRLLRTSSS
SSCFAGVQVCTEIMHCVQELQSWQPDRISRHIEKALRSKNDNLISCSEHLAEIVESLSLV
SNHELLKESIAVERERAKVHANKQTEEMDDINQIVDLLALIREYLLKNECFGTINGVSIP
LYFRCPLSLDFMLDPVIVASGQTFERSSIQKWLDQGLRCCPKTRQYLSHTNIIPNYTVKG
LIANWFQENNVKPPNSSDRTNGNGLPAQDVIHTDSFHCSVHSSDSLSRSSLEVGDAVGRL
NIDEPSVSGEMSSSTCQGLETEKSNHQTSEQSYTHSRTHSVTSAVSSCDYVPSSATEMSR
ISDRREKFGEIISEPSPLSSSLSGRGSRSAKASSEMNEKGNNNHARVHSFSFSDLGHDET
TTSSYVNELVENLKNPSNAMQTAAAEELRLLAKHNMENRIIAGKCGVIDPLISLLNSDVK
ITQEHAVTALLNLSLNEEIKARIAEAGIIEPLIHVLKTGTDTAKENSAAALFSLSLLEDF
KMRIGRSGAVKVLVDLLARGTVRGQKDAATALFNLSICHENKARIVQAGAVKYLIQLLDS
STGMLDKSVALLANLSTISEGRLAIVKEGGIPLIVEIVETGSQRGKENAASVLLQLCLNN
TKYCNLVLQEGAVPPLVALSQSGTPRAKEKAQQLLSHFRTQREGAAGRKKK
>Sgl54454 E3_activity/RING/RING 21.9 10.3
MGQKQSRDKLMYHYVLNKDVGGIQFLSKQGAGLEWKDKEGKTPLMVAAKESDLYDVAKTL
IEMGANVNAFCKGRKGGTPLHFAARQGLDNTVALLLSHGANAFVENREHHTPLDVARNNG
HNLVVREIESRVCYFAGHIRENFGPGLSDVAVAARSQSSTSAIIWVVVVPRSPHNPPKPP
ILELVIYSTPEDAAPRKIVSLRRSKMKAPRFDQPSPTLTIFDKQTKTRYKFSSVTFNNKQ
QLRRLYNACKGISQAAPSAAQMMASETTNSPLHPTSQINSPAWRTPGISSPPMSPNNNVW
VHESPRRADQYSNANSGATQTQLNPAAVSSPTVSVPLKNNTCSNSNNNNNNNDSTNIIDV
DEGSTSVGADTTIQPAGCDSALCVVCWETRVEAACVPCGHVSTCMSCLKKIKDNKEACPV
CRGEINQIVKLSWYLKFSGL
>Sgl54455 E3_activity/RING/RING 23.1 9.6
MGQKNSKDEMVYQKVMEGNVEAIKALFSEGARLEWIDQQGKTPLMAACMDSRLYIVAKTL
IELGANVEAYRPGGHAGTPLHHAAKRGLHDMVKLLLMHKANPFARNDECQTPLDVARAKG
HINVIRVIEDHICYYSGNVRESMAVPGILESLVPHRLTRKSSKKCWVVVVPSGPPNKKKP
PKLELVVYSSRQAHQPRTVIPLWKSNIVEPKFHESDPSLTVINESTKTRHKFISTIEGDM
QQLVQLYSACKGFPKVMPSLVPSSSSGTSPSLPAASASNQPELSSVSNSQSSSNTNGWGD
LDGIATHSECGPSSVPPPTTASCNGWANEPTTEELNGWADPSPGPSRPTISPNVAPPPVP
STPSAPPLPMDDLDEGLIHYPAVDMVPVDLPVASGDAKGKAEDTCCVICWDAPIEGACIP
CGHMAGCMSCLTEIKSKKGDCPVCRAMIDQIVRVYAV
>Sgl54497 E3_activity/RING/RING 16.2 7.1
MEEVVLFIDDDFNNSPNYCRICHEAEFESSRKLETPCSCSGTVKFAHRECIQRWCDEKGD
IICELCLQKYEPGYTAVPKQPKKNVVQHEVVSIRGSLEIPRTEQEPQNVDLLAIAECTAE
AERSASCCRTVALIFTFLLLVRHLIEALLGGAEHQPFSLLTVLILRSCGVIIPMFIIIQT
ISAVQNSIRRHRILHETLMHNTRDTDEEEQLHQR
>Sgl54504 E3_adaptor/Cullin_RING/DCX/DWD 95.2 19.1
MDVKNYASANLMPSLPSKTPSISNKVQESRHFDERDRVTGRAIVADKVPENSHFEGKERV
AGHAAVADVDIDLREVYLLVLHLLSAGPCQKTFAQLLNELMEHQLLPRRYHAWYSRTGVH
SAEENDDGVSVPLTYEKLLHRYPHIAKDHLVRLLKQLMLAPPGLSLGVGNGPNAADVPTL
LGTGSFSLLSCDRIAEKKQVKRVPRYLRWPHSQIDQVHALHLRAIGGGFTRHHRASSIHA
ACYAIAKPSTMVQKMQNIKRLRGHRNAVYCAIFDRAGRYVITGSDDRLVKVWSMETAFCL
ASCRGHEGDITDLAVSSNNALVASASNDFVIRVWRLPDGLPISILQGHTGAVTAIAFSPR
TAYQLLSSSDDGTCRIWDARNSQFKPRIYVPKPVDTGIGTSNQNHQITCCAYNANGTVFV
TGSSDTCARVWNAPKLSIDDSEQPYNEIDLLAGHENDVNYVQFSGCAIIARSVTGDALKD
DQSLKFKNLWFSHDNIVTCSRDGSAIIWVPRSRRSHGKVGRWTKAYHLKVPPPPLPPQPP
RGGPRRRILPTPRGVNMIVWSLDNRFVLAAIMDCRICVWNAADGSLVHCLTGHTESTYVL
DVHPFNPRIAMSAGYDGKTIIWDIWEGTPVRVFEIGRGKLVDGKFSSDGTSIVLSDDVGQ
IYLLKTGQGESHKDAQYDQFFLGDYRPLIRDALGNVLDQESQFSPYQRNLLDPLCDSSMI
PYPEPYQSMYQRRRLGALGVEWRPSNIKFAIGPDFSLGEDYQMAPLPDPEAIIDIPEPLD
AALWEPENEAMTDDAGSDYDAAEEYSSAKEQESLGTSSYDDTDSDAENFDVKQRQKDILR
RSKRKNERPEAEFTVPGRRIRRKRVEDCSGTSSQNIRDRRMGSNSKTTKKKKKSLKAKLL
RPQRAAARNAKNVFSSIPETSSLGEDDEDGSEEESSDGGSFSQDSEIQIDEHGWVLQNSF
VQGGEKTLFDESATVMDPIQLPESQASVGNKKKLVLKFSVRDSKKSLPKTDDKSEFDPSS
SLLQKEEDKQCNLGDEDVDLHPPAAIYPKPFESSNRVKIKCKGLLEKIPNDTSATIGSDT
RREVSCSRQYEKGSREDGGDYSIENDLVFSNGNSHELKENAQPVPTRIKIKSSGTIKQER
PPKLKLVTGAKKAVATEDSSVSYAASYGSDVEENISNTGYYETCPGADFPDADTDVVRRT
RSMEIKASTRETGRGSSKLKLRKSSRSAGPSKISENWSRDSILNSSIPSRSRSSRSRQVD
SFEDDQGPPRMSLSNLGVGKISWLMLSEHEPGYRYIPQLGDEVVYLRQGHQEYIESYATH
ERGPWVTMKGRINDVETCLVEGLIYAPVPGSGESCCKLTLKFVDESSCVFGKSLRLTLPE
LLHAPDFLVEKTWYDLAVSRSWTPGDMCSVWWRHENGDGGSWWEGQIISAKPKSSDFPYS
PWDRYAVQYQGDPGPELHSPWELHNPDFRWEPPHIGFDMRNKLLDYLSKLERRKQEYGLI
NLEQVSQRPDFLNRFPVPLSLNVIRSRLTNNYYRSVQAVKHDINVMTSNAMSYFSKNSPH
SKKMKRMADFFERMFSNL
>Sgl54525 E3_adaptor/Cullin_RING/SCF/F-box 15.1 0.0
MKESKTEVHHHRYVPVDLINDILLRLPVKSLLRCKSVSKSWYYVINDPNFIKLHLRRGLE
TDSNTSLIMIDDHYTQLTQGLMSVVCNVSKHADTKVAHQLCYPKHIIPPYAQCVGSCHGV
LCFLYVPHRRDQHYCLYNPATRAYKVLPVFNFTIGEEFHAIMSIGYDSISDEFKVMKIVY
LLILGCSKIVQHQTLLYSSKADAWEIIESPPWNDNVLRTSSAVFANNAFHWLSPSSKEIM
CFNISTQRYYVKLVPENISSNSPKLTALQGQLCLVTYEFDIWILKEYDNDEGWTQIFRNL
YEIFNGDDLQANWIFELNISCLRDGSNNNIIIVPSKGRDITRRRMHQVLIYCNLKYGTLK
KIDISYGFEPYNLLLADTQPWVESLLDPAYCRAALS
>Sgl54541 E3_activity/RING/RING 32.6 6.6
MKIFSGNILYDFTVSEIDAPISSVETDEFQIEFHYRKFQSSWQTPDFEARRSIKCHRDST
QSFVTDALQEFEVQENARVDMATHFRFYLDRLLRINMRRRRSCSSEGACVKVSLDAKEIS
PERLAEIGRRRERASRRMTVEMTTVTVTETVVNLPAKKAVVEKLERERVVVVDDEKECAI
CLEKFGERGEGIELPCLHVYHKECILQWLGRNHFCPFCRFKLPC
>Sgl54616 ULD/UDP/UBQ/UBQ_PIM 97.3 1.4
MQIFVKTLTGKTITLEVESSDTIDNVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLADYN
IQKESTLHLVLRLRGGAKKRKKKTYTKPKKIKHKKKKVKLAVLQFYKVDDSSKLQRLRKE
CPNAECGGGTFMANHHDRHYCGKCGLTYVYQKAGGD
>Sgl54622 E3_adaptor/Cullin_RING/DCX/DWD 80.6 37.2
MEEHKVWSVNGGQYLGEISALCFLHLPSSLSSLPLLLAGSGSEIILFDVNLGRQIKSFFV
FEGVRVHGITSSCMNYEENSSSVTFKVVISGERIVKLYSLGLQFRSGILDEPDVLADLTL
LQLLPRFTHWVLDFCFLKNGRFSLEEGCCYLAVGCNDNSVHIWDVLMSRLLFKVLCPERC
LLYSMKFWGHDLEALLIASGTIFNEIVVWKLIRQHGTLPITSAEQEPDVMSTLVDVHSQE
CLEYEAEIVSKLAGHQGSIFCLSWSDDGSKLVSVSDDRSARMWIANAELNLTDALTKSPN
LYSAGPVLFGHGARVWDCCISESLIVTAGEDCTCRLWGLDGKELTVIKEHIGRGIWRCLY
DPNTSLLVTAGFDSAIKAHCLHSSLPAISGSSVNKVEERKEEVFRFCIPNSSGQSGLMDS
KSEYVRCLKFARKDMIYVATNHGYVYHVRLSDGGSVECTELIRITEEVPIICMDLLSKNV
SELSLEVEDWLAVGDGKGTMKVIRVICSGGAAHVTVNISWSAERERQLLGAYWCKSLGCG
FMLTSNPRGAVKLWRLPETSSYDSVMNFDVHLVAEFMSPFGARIMCLDASCEEEVLVCGD
LRGNLVLFPLSKRTLFGGSVLSIEKIPSVTYFKGAHGISTVSSISIARINSSLIEICSTG
GDACICYLEYSKDQQTVEFVGMKHTKELSLVQSVNPYHHSLEDSANISYAVGFSSTDFLI
WNILSETKVMQVNCGGWRRPHSYYLDETPEICSGFAYVKDDFIYVHRNCLPDGEKKIFFR
HLHLQFHGREIHSLRFIPEDECATNNFHPKLSWIATGCEDGTVRLTRYNHGIGKWAMSNL
LGEHVGGSAVRSLCFASKIHSVDSKVVEVTSGNPGTNSSLENTECPCLLISVGAKRVITS
WLLRRRLKIEGDASVYGQSSSRPISLMSFKWLSTDMPVKCAHTQKKTQNRKNSVKSLDKV
PASESVSTSIEMELEPHGDVHDNDWRYLAVTAFLVNVAESRFTVCFVVVACSDATLMLRA
LVLPYRYWFDVASLTPLSSPVLALQHAVSPVSHVYQGKLMMKNIYIVISGSTDGSIAFWD
VTESIEAFIHRVPSFHIEKSIDFQKRPRTGRGSQGGRWWKSIGAVTGKEKSDAEVISSDN
GIIDGSPATMILKGKNISSDHTEIASSRSVESLNDLSERLDEIKPLHVLQNVHQSGVNCL
NICSHIIGNGLPFSIISGGDDQALNFFQFVVAPSPTQPNFYDIGKNDRTSESVSPEYLIQ
HDLKQSYSIKFSYQTKSIAAHSSAVKGVWTDGTWTFSTGLDQRVRCWKLQEDGNLIEHGH
FITSVPEPETLDVRSFGGNCYQVVVAGRGMQMVEITLSSGDDKLD
>Sgl54647 UBD/UBC-like/UBD_UBC 157.5 0.0
MSTPARKRLMRDFKRLQQDPPAGISGAPQDNNIMLWNAVIFGPDDTPWDGGTFKLTLQFT
EDYPNKPPTVRFVSRMFHPNIYADGSICLDILQNQWSPIYDVAAILTSIQSLLCDPNPNS
PANSEAARLFSENKREYNRRVREIDVRLGKKDEKPWGKNGRRDDVKEIGYSPIVLLIIRQ
IDLG
>Sgl54648 UBD/UBC-like/UBD_UBC 156.8 0.0
MRDFKRLQQDPPAGISGAPQDNNIMLWNAVIFGPDDTPWDGGTFKLTLQFTEDYPNKPPT
VRFVSRMFHPNIYADGSICLDILQNQWSPIYDVAAILTSIQSLLCDPNPNSPANSEAARL
FSENKREYNRRVREIVEQSWTAD
>Sgl54695 E3_adaptor/Cullin_RING/SCF/F-box 14.8 0.0
MIHQSELLENILSRLPAKSIGRFRCVSKPWKSLLSQPGFIKLHLRRTKCLPRKEYSLMMV
CDESHSLYSAQLKYAHQMSNDTSITTFATKLDFGDRKFSSEECLDTMASCDGLV
>Sgl54732 E3_activity/RING/RING 34.9 7.3
MENFEDGSFEDRYIGVYDYIPKFIGGAVSGALTGVFALAGAFTGAITGALAGRASDSGLI
RGAGLGAVAGAVLSVEVLEASRAYWCSQQSGLRSSSSMADFIEELLHGRFIEEQLPPAVL
TGYYWQASIANVVYDDVYDVYGDYAPCGLSGDSLKELPCHVILDIRPTDNISCTICLQDF
EVGETARRLPHCSHTFHQNCVDKWLITRNSCPVCRRDV
>Sgl54741 E3_adaptor/Cullin_RING/DCX/DWD 37.9 0.0
MSLISQNAVIKDKIKKKKLLRRNDDEGEEPSLMEEGRKDLSENGGSDVEAAVSHKKKKKR
MNKEAKQMLIEEELEMQNLGNFLFGSVHSPVEFGKENEVENQDEVDVDDSALFVMDRSGN
DTLLVDGEDVGYQVGINDEDGDKQRKPAWLDDEEENVVNISKVNRLRKLRKEEDETVISG
LTYVSRLRAHHAKLNPGTDWANLDSKSKPYDSDEEPEVDNGAVVASGYKHVDDILKSNEE
LVVKRGSKLLPGIIENSRLVDANAEDPSNGPINSVQFHRNHQLLLAAGLDRKLRFFQIDG
KRNKLMDSIFIEDCPIRNAAFLPDGSQVIVAGRRKFFYSVDISKGTVDKIGPLTGREEKS
LEVFEVSPDSRTIAFLGNEGYILLVSTKTKELIGTLKMNGTARSLAFTDDGQQLISSGGD
GQVYHWDLRTRTCLHKGVDEGSINGTALCTAPLGSLFAAGSSSGIVNVYNREEFLGGKRR
PIKTLEHLKTEVNFMKFNHDAQILAICSRMQKSSLKLVHVPSFTVFSNWPPGNKTLNYPR
SLDFSPAGGFMAVGNAAGKVLLYKLHHYQQA
>Sgl54753 E3_activity/RING/RING 31.6 7.3
MWTRASSAIANCVHLKNDLLNRNSECSDDDASFDANQEEGLECPICWESFNLVENVPYVL
WCGHTLCKNCVLGLPWAALKFPTLPIQLPFFVSCPWCNVLCPRMMYKGVLRFPRKNYFIL
WMVESMNGDRTRSYTSGNGEFRQPSSWNGNVGMNTHSHVRNNREISTEGTELNHNNVSLL
RQYFSRERFSVSLRKSLVFVVHLTAKFPLVLIFLLITLYAIPASAAILALYFLITVLFAI
PSFLVIYFAYPSLDWLVREILT
>Sgl54772 E3_activity/RING/U-box 30 0.6
MSFNTDGNSSIVGNFADGIDDVEEFICANVGVLAISNERFQQVFEFVQTGNQAFRRGRFE
EAINCYSKATLVKPGDPIILSNRCAAYIRLSQFLKGRAPSASEYSPLYGLDPTTHAELAL
KDAEKVVSCRKNSVKSYILQADALILLERYELARGAVIAGLTLDPLCTHLQDLLSILERT
CTGLVLERSRVKPERSDDFDCTLCLKLLYEPVTTPCGHSFCRSCLFQSMDRSNKCPLCRT
VLFITPRTCAISVTLNNIIQKSFSEEYAERKLENDNLAKLGVDLMPLFVMDAVLPCEKLP
LNIFEPRYRLMVRRIMEGNHRMGMVTLDSTTGQIADFACEVELTECEPLPDGRFYIEVEG
RRRFRILRSWDQDGYRVAEVEWIEDTCPGEGTREKTELQELARNAAEYAQMWMMRAKEAS
KQDRRRLGEILNVEAMMPSREDPERFSFWLTTLTKRRPSERLELLRLKDTKERIKRALIY
LRQEEQGCRLQ
>Sgl54774 E3_activity/RING/RING 38.4 3.1
MFDIPIHCSHKTTSSSTTPRSISELPPKQLTVYLISTKYQRVVYVNNDNNNDNDNNSTVF
VSRHEHPSIFSRKYVNPVDPSCVSCMPYILGAILNHGYVGATDALGQYRCLREEISRKVA
SMLENNENYSVITYELRKYDHSDFRPCDEEEYRTLVAQGEEFEEVVISDSDVEDEEGLVP
ASESAIERLERVVVDDEGEFVFEDVVSDDRTCSICLEELVMLNEDDDDDDNKSKNKFIGI
IRLPCKHLFHEDCIVEWLRKNHVCPYCRFELPIVD
>Sgl54775 E3_adaptor/Cullin_RING/SCF/F-box 20 0.0
MANIVPTKYSKENKSNRSSPSEAKSHSSYWLPEDLILEILVRLPLKSLIQFQIVCKRWKS
LIKNPKFAKTQLHYSNQHHLPSLQLIFQYNSVLASYIDLNDYLDNPTKANEFEPKFVELS
SQPFQKNDYDYIIVGSSNGIICFYLFKDNKLCLWNPIIHETRFISLPPNRKDEYCRHDIL
FSAFGYAPSIDDYKILLLVKKNKYRDRSLIVYSLRRDNWSEYDHQFSKVQYFYDWFRNCQ
RFGRRVEDVVFNDALHFDMGELCSCEPSYIVKFDMVKECFEKVVDLPRAQYYSYWDATKM
VVTEDSKTWYYQPYYEKSYKTDTDTGATAVIKRQVVEVFKLLDNNSWEMKVVYQGSWEDK
DGRELYLIRISNNGKVLLFKEMTCGPWSIGKLHILDLRHGEPSFIQVNNEDNPPLETFPA
HKYAKPNSASYVPSLVSPYYSC
>Sgl54776 E3_activity/RING/RING 37.7 2.1
MEDNNVMGGVVVHCDHKFRHPYRPFPKQVKQLLMVRLNTRCYQPVVYTNNGTPLVSTEPQ
PCSSLNIYTRSRNPRCRQCFSEIIHFLVQRHQYSFTDAVNEIYRLFDVVERKVQSMLLRH
DELNENNDEHLSRMNFNEVFNYEVRIIINHGYRLCLEEEYRALVANGVAFERLVVTVIPA
NNTVSLLVIKGLEMVSNKTDFQEELLVKEEDNVCAICLDKLSIKVNKDEEREDDPTVQEK
EVTTIKNDDNKTKNNKLIVKLPCKHVFHEGCIIKWVRQHHICPFCRFQLPVILFDALLHC
N
>Sgl54777 E3_activity/RING/U-box 27.9 0.1
MLAVNIYTRSRNPHCKHCFFETIDFLVERNYSLHDAIDEIFRFFDVAERKVRSMLLGYDE
LNNDNEHYCSRLKFNEVFNYEAPINLGYRLCVEEEYRELVANGVAFERLLVLLIPANTVI
SRLLVIKGLEMVNNNTDVQELLAKEDNVCAICLDGFSTKVDKGDEEKEDDPTVQEKAVTT
IDDDDNKNKDHKLIVRLPCKHVFHEGCITKWVREHHICPFQHRYYSVFDALDEYFRFFDV
VEGKVYSMLLGYDELNDEEQRSHLKFKEDFYYEVGINLGYRLCVEEEYRTLVADGVAFEV
LVVATPANSDTMLVIKGVEMVDNNNNNNNNNTDFLELLGKEDNNCPICLDEFSVKVNKHE
DSQDDPTAVQEEEDTINDHDDHNNNNTKDHKLMVRLPCKHVYHRGCISDWVQHDHICPCC
RFPLSFDVFL
>Sgl54849 UBD/Alpha-Helix/UBA 18.8 0.0
MAFSVLTRNSLRNLNTFQFHQISLLQTHKFAPFSNTSNSKSFNLSNINQQIQHRKQISLS
TLLQRYGFSSSEIPTFLEKNTFLLNSNASEIEQSLKILLLSFKLQQNLLVSLIYGCPNVL
DLNFLKKWELGISSLGLLVNSPRVIKSVLEFSRKFGITPDRFCSFIEKFKGLGFSDGTII
SVLGMFPGVIMIDDHEIEKRIGFWKSIGVEREGIDKIYHCFPGVLGFKVENRLKPLLNEF
MEMGFGRRLVRQEIIREPRILSLELGELRRCLELLQRLRCRESIKEKIFCEGEFKAGFAV
KLRVECLCKYGLIRSDALNILKREPRLITYDIEDIEKKIEFLLERMKLEVGSLIEVPEYL
GVNFDKQIVPRYNVIEYLSSKGGLGFEVGLRDIIKPSRLRFYNLYVKPYPECENLYGRFT
ECVEKKARHPTGLWKHFKPPKSPKSKEDVKNLKSFTEFLI
>Sgl54854 E3_adaptor/Cullin_RING/DCX/DWD 96.5 2.1
MGIDGNFEQILHEGNLFRDVNLLIVAHLRDNNLIQAASAVASATMTPLNVEAPPNRLLDL
VSKGLAVEKGEPIKGVSASTLFDSSPTVPAAYGSIPVPRTTAIDFSAPLDVKGASKSFTE
HETRHVSEHKNVARCARFSPDGRYVATGSADTSIKLFEVAKIKQMMLPEARDGPIRPVIR
TFYDHIQPINDLDFHPQNTILISGAKDHTIKFFDFSKTTAKRAFRVIQDTHNVRSVSFHP
SGDYLLAGTDHSVPHLYDINTFKCYLTSNADDIAANAAINQVRYSSTGGMYVTASKDGAV
RLWDGVSAKCVRLLKGAHGVEATSASFTKDNRFILSCGKDSTVKLWEVCSGRLVKQYIGA
THSHLRCQAVFSFTEEFVLSIDEPRNEIVVWDALTAAEVTRLRSNHVGPPRWIEHSPIEA
AFVSCGTDRSVRFWKEVL
>Sgl54883 DUB/USP 116.9 4.2
MHLPVLIFQLYGLTVQASFLGESKKYKAAIIRIDSPGGDALASDLPEEADLFAKSAQYAY
AQFRDKAAHSRSMPFLLPLHCSSSKCQIIHWRQGHKHECHPQDHSASEKDDFDENADSVE
QCKTNDISSAEYFSRMDDKNISQHRHDDVFDLPVPRLSTVTVASFDTGRSSCGENETLSS
HIDATKMGHREDKINSMEMNASTGLTPNGAVNSVRKLKKKSRQDDRRKFRPSNSEHSPGS
QQDKSDRTFGNVPSSKAEEVLFVDNDEQKHSSYSVPPRRSVSNELSRNGLASSFQKVVHH
FKASNQKKPSPHDTLLGISANRNCKTIFPYDAFLKLYSSNEVELRPFGPINCGNRYAVDT
MQSVCAELAGVVGPEREESTLVGMTFGGFLHSKIRCLKCNNKSEKYERMMDLTVEIDGDV
RTLEQALRRFTASEMLEGDNKYYCNRCKSYKKAKKKLTIFQAPNILTIVLKRFQAGSFAK
LKKPVQFPEILNMTPYMSDSSDKDKHPQYNLIYILWSAHP
>Sgl54889 DUB/USP 123.2 1.7
MGHREDKINSMEMNASTGLTPNGAVNSVRKLKKKSRQDDRRKFRPSNSEHSPGSQQDKSD
RTFGNVPSSKAEEVLFVDNDEQKHSSYSVPPRRSVSNELSRNGLASSFQKVVHHFKASNQ
KKPSPHDTLLGISANRNCKTIFPYDAFLKLYSSNEVELRPFGPINCGNRPEREESTLVGM
TFGGFLHSKIRCLKCNNKSEKYERMMDLTVEIDGDVRTLEQALRRFTASEMLEGDNKYYC
NRCKSYKKAKKKLTIFQAPNILTIVLKRFQAGSFAKLKKPVQFPEILNMTPYMSDSSDKD
KHPQYNLIYILWYVSSS
>Sgl54925 E3_activity/RING/RING 10.9 14.4
MFDMSGRRYSISWRKVAMALQGFGAHALLFTFTLLLVLKLDHIISCSWWVIFLPVWMFHA
VVARGRFSLPAPSAPHDRHWAPCHAVVAIPLIVAFELLLCVYLDSLSVYGVGAVSLKIVF
IPILAFETVILVDNFRMCRALMPGDEESLTDEAIWETLPHFWVAISMVFFLAGTLFTALK
LSGNIDSLGWWDLFVNFGIAECFAFLVCTKWSNPMIHRSSLTMANAASSSTVSFLDWNSG
LLVYPEEEQNQESSLCGLSDIGGHLMKIPIIAFQVLLCMRLEGTPNGARYMPLPVLFSPL
FLLQGVGVLFSISRLVEKIFLFLNSDAGQGWYFTFSAKLRESLAFMHHGSRLLGWWSIDE
GSREELAKLLHDGPSGYNTFCSYPPEVVKKMPKKDLAEEVWRLQAVLSQQTEMNKYTKQE
YEKLQNDKVICRVCFERDISIVLLPCRHRILCRICSDKCKKCPVCRVAVEDRLVTVNLLA
DHL
>Sgl54951 E3_activity/RING/RING 34.4 42.9
MAVLQQNLPCDSDGVCMVCKHKPSEHERLVCSTCVTPWHADCLVNKPESMASLSKWECPD
CCPEDDDDDDNNGGGGVASVVTGPAGELVAKIREIEADASLSENEKAKKRQELLSGIGSS
DENGGGGGKVKDDNEILQILGDNIKCSFCMLLPDRPVTTPCGHNFCLKCFEKWVGKGKTS
CAKCREPIPKRVASQPRINDSLVLAIRMARSSKPAAAEVPRMIQYVHNEDLPDEAFTTDR
AKKTGKANAKSGRIFVTIPNDHLGPITAEHDPVRNKGVVVGDSWTDRLACRQWGAHFPHV
SGIAGQSSFGAQSVVLSGGYEDDEDHGEWFLYTGSGGRDLSGNKRTNKLQSSDQKFTKAN
ESLRMSCRKGYPVRVVRSFKEKRSNYAPEVGVRYDGIYRIEKCWLKKGQQQFKVCRYLFV
RCDNSPAPWTSDEHGDRPRPLPNVPELKKALQLTERKESPHWDFDVEQGCWMWKKPPPPS
RKGKKTGAGHARKSSKAKLMKEFSCLLCHKVLTLPITTPCAHNFCKACLDGAFDGQKFVR
ERNTGGRSLRTQKTVMKCPSCTTDISEFLPNAQVNRELMGVIESLMRKFEEEEKADSEAS
SGDLNDENEESLSEGAEISTSDAEETASKPAKEEVDVAKEEPEVVEKESKDEAVYENVDE
VKAELADAKKRVAIEEPEVVGKENQKEAVCEDADEVKAELPVAKKRGRPKKNTVANGAAV
SAVTPTGARKSRRLANDGNVSPSSPLHLRSDNELE
>Sgl54954 E3_adaptor/Cullin_RING/DCX/DWD 61.6 2.4
MNGRGILKKPKREIESDNEEEHNKINHNSSKYDDDNDGDDDSVSISNYEEQEEALVALIE
HRSKEVEHLNNRISYYQSQLKQAEQRLDDSQGKLVNVRRKISDLKWNNSAKKEGKKEHRH
RSRSPVNGGSLQRQPHNKPQLLISNTSQKSSRQTPSETGPKASSSHYDSPVKARGDKSHG
TPSRSEDSKSDAVGAKRKLETSEHKELVSKVRNSSSPTMIQCYASTHISSQHKRKIRSLT
LCPVIDKLFITSALDGMVHLWQIQAKGSGATLLSSTECLSPKQRRWPEDIAWHPEGNRLL
SVYSADGGDNQISVLNLNKNQSSRVSFLEEKPHVRGIINCVSFMPWDDTCFATGGSDHAV
VFWNEKDGGDDAWKPKTLHRNLHSSAVMGVAGMRHKPMVVSAGADKRIIGYDVLAGRADY
KYLIESKCMNVLPNPCDHHLFMVQTGTPERQLRLFDIRLRNSELHSFGWKQESSESQSAL
INQAWSPDGLYLTSGSADPMIHVFDIRYNAHKPSQSIKAHQKRVFKAEWHPTMPLLISIS
SDLNIGLHKI
>Sgl55006 E3_adaptor/Cullin_RING/DCX/DWD 57.7 13.3
MDEECKTEINGTQVEGTEIDETQIEEKDSNSQSEVAPALIAVHPFDQSVAVAIGSELRVF
NLAKNCSISLGNESSELLHKDAIRAVRFSDKGKLLVSAGDDKLVKIWSTETWQCLCTVNS
EKRVSAVVISKDEQYVCFADKFGVVWIVDLVGLAENQPCSNKKAVALFGHYCSIITSLEF
SPNGSFIVSADRDFKIRVSVFPRSPLKGVHEIQSFCLGHSEFVSCLTFVHNSDFPQGFLV
SGSGDSTVCMWDVTSGSLLCTSEVGREANLSEESQPAVIDLCATDDGTVVAVAIQRLQGI
LLLSCDLSAAKLSTLKMVPVPGEAFIPTRLGMALSGNFLWMVTGVSNLPGSKAASFARIR
IVSSFKESDLEPRVLEDQEIPGGEQLLEKLQGSVSVDSADFSAAADTLNAAMSSLLRKKQ
YSNEKREFRKKTRNDKKYNQ
>Sgl55025 E3_adaptor/Cullin_RING/DCX/DWD 169.5 27.5
MSSTQTQQQQQQPQPQPAAAYQPYRLCKTLATHKRAVSSVKFSNDGELFASGSLDQTIAL
YSSQTLTLISLLVGHTDGISDLSWSSDSHYLVSASDDTTLRIWDARASSHDCVKTLRGHS
DPVFCVNFNQPSNLIVSGSFDETIRVWDVKTGRTVHVLRGHSLPVTSVSFNPDGSLIVSS
SHDGSCKIWDTATGTCLKVLIDDEIGVSFAKFSPNGKFILVATLDNSLRLSNYLSGKFLK
NYQGHTNKTYCIIPTFSVTNGKYIVSGSEDHCVYIWDLQGRNMIQKLEGHTDAVISVSCH
PKQNMIASGALDNDRTVRIWVQDA
>Sgl55075 E3_adaptor/Cullin_RING/SCF/F-box 16 0.0
MRNCRRKINWSEFPDEILRFIANYLKDSPKDLHNFRSVCEKWRRATAIPALLPYDMGFET
LFSSSVFLLRSPDSIPPWIVTIVEITKGKLQYCHPLTGEQFLNIPEDFNFRRFNPRRLSL
DFHMSDVNDKCNLSRALFCHDKVLLFFKDQCSVPSIVDDCSLLVLFRGGQLGGSPPVRPE
YQFGTELPWFDISYGSLDKFDEILCFNGAIYALDRLGKLYQMFTHQFAVLKMFVGKPVVK
PDCVHKGWRKRLVGSVSTGKLFMIRRSDEVIRVSYSFFVPATEFIGFKDCVIFSYDAFRP
YSKAAETKCDRKEIQIFQLGCHDGGTIKSLSDFPGFLVENFCPPSWAFQPQTSTFPEDCQ
SDPEEDEMMEPGPTDQEAGASAQDHVSSPSRIPKSEEQSVEIPSTSAAQAKSASHLSGFD
QKHEEAPDNSDSKDFRADSASVTSSAMNSMECESNNKFYEGLRIKPNLLPTLQTVWIKHG
NPVSESAVRSKDMLSCALESLAKMINVLQSTTARTLTDSLAKDLDSIMFDLQCVGLKVDW
LVPFVKRALAIQKSKPVIESIMAIEKEKDRVDEEEREFLMRSAKKKQELEDKKACVSAAL
PFPEPFNLDQCLGEGLI
>Sgl55079 E3_adaptor/Cullin_RING/SCF/F-box 21.1 0.0
MGHSCSASWSSKLPRKLIHNISNRLTTRDQLVRFKRVCRRWRKHSPPLPVNNLSFTLPLT
IPVSKSCKTLPFHSSTRSLVLQVSSIYLITPSHPSQDCHGSLKPWMVMVEESKPGKLRLR
HSLTAKRINKFPPTLDMSRFRALELVRGFSFKNNDRVRKVILCSSTSTCLEVIVLCHDGN
VGKLTVRVSESQAQHKKRSADSETTDDTDEMEEDNDQEGFSWKRLKRERSISCFKYLDDV
VEFKKKYLIVDRKGKLYELDIESMKVVSLLVSKPVYEEDSKWHIQRQKRLVVDPTSGELH
LVVRERSKATRIGFTIYKYNENSNKWDIVEDLGRDRLLFVGVNHCFFAKAKDFPGCKGNC
IVLAANCFPGYRSNNATDQALFGDNDDVEVGVYRLGKGDNFNFLSAFNPKHSKSIWPPPT
WFSSKRYAFYGHNHSFCSYIRIISNN
>Sgl55084 E3_adaptor/Cullin_RING/SCF/F-box 11.7 0.0
MASHRKTPRATENWSNPPPEIISAIKKRLNSTIDVLRCRSVCKNWRVSINPNPNSSILSP
FLPLKISNPTLPFNNRPNETLILFARTVLLVKPLSSSNDDSTSTSSWILTVEEVTQGKLR
ILHPLSNDRVTSLPPNFPKSLNLLDFSVSEICKSYGFKHASDGKDVCGVHKVVFCSDFTA
MVLYGEGILVSARLKKGKWGFVRDSLVTPFSDVILFNGNVCAVDCNRNVHTIDHKMMKVI
KSVVDDRILRNSLVSTNGGKRLVERKGKLLLVTWWIGKLCSTDRSETVEVMCYDLNEKSN
AWFETRLLGFVLFVSLNWCFLVCPKDLGISDYLPKIGEQEIISCSYGIDDLHYDTNFPPW
DVKRREYLVLSRTCFNSSALPVFMKYNSQYFEGARVNFSVGLFNYMHEEHDRRNYIYSSI
RGAIWPPPFWFWPDDDTSSRDDEDDEDLEFCVEDVSTDSKQEMPPSLIVPAVNGIAKNNA
QDLRTKEIDMSTFLEDSHALRIQNVNSCASTALFERVKIKANLLTTLQNIWAKHGNILEE
SRIRSGDLIAKALESLATTVLILQRSSGRSLNYIQAEYLSSTLSDLQHMHCKVDWLVPFI
EKALAVHKSKPLVDSLKEHDEAKARVKDTKLKLLNELAKLDEVEDDMKLVFETIPCLESV
DLNESLGEGIC
>Sgl55087 E3_adaptor/Cullin_RING/SCF/F-box 13 0.0
MEIERVIDWSELCPEILSEIADRLGTRPNVYNFRGVCRNWRYALSYIPPTLPYFSPLFPH
TSDSDLLLFLTRGAIHLLVADGVYLLRPRKNPASSKPLLITVEELFRGKLSVRLPLTRII
ATEHLYKNEAFLKTLDLSDFHVYVIARGYTLRATFAANAGLSQRNKLVLFANPAAFEPLS
ISDYTALVWFDHGPVVWVRLSQPSDWGFLGYKGTSKFDDIVNFNGRVYGVDRIGKVYAVN
YDFKVYKLNEESSKLDEVSGIGDDQILFVSFDWCFFALAADFPGVKGNCIIFSKSSFAMY
SESTSVEYFCFGRDDKDFELDSVLKWENRIPCKLDLSSFSRLRSKARGLEMMLSEIHES
>Sgl55089 E3_adaptor/Cullin_RING/SCF/F-box 16.7 0.0
MSRRKIFWSELPTEILSSIAERLKLRSDVLHFRAVCRTWRKSAPSSLLTGKKSLSPILPH
FFSIKPCNEAMNRGQWNFASNRLVLVANSVFLVHSIANPNFEPWLFSVEEFNPGKLYLRT
PLKRTVVEHMPKGFPTNLDFSRFRVSEISRMYSLSFDPSDSSVKIKNKKNRVSQCFDRVV
LHVNSDKCDADTVAIDDCTLMVLYYDSSVGSFGKISLRDRQFSVLECCSIKKFDDVVSFK
GKVLAIDRKGKLYEECNGMMSRITDVPETEGGLGIGLGGDRKKRLVKSCGELYLVYRCSW
REKVAFKVFKLEDDGKMMKWEQLKGIGDDRIIVATHDGCFFVPSKDIPSWPGNSLVFVRG
VFPAYDSIHKADLELFKSRNGPPSEIAIYNFGSGTCKVKVCNSPKVLWPPPAWLSSDPHL
PNSSSSHMNEEEEEKGSLVQNCLESSSINENTSTPEFQGDSQVECISPLDIQENLPAEDA
GALDITMQIQPNTTIYIDSTPTTTISDNAITECCDVISKSPESDVAKTKFQGVDVSSDLI
PTLKAIWAKHGNILEGNRVQSNVLVAWALESLAKMVILLQNTSGGSLDNSQVDYLSSTLC
DLQLMQLNVDWLASSVAKVLKLQKARTLRAEMKDTLSEIDKVKTLVTDFKLKFLAELSGL
EKMLDEKRKMVHESLCDFNCLDSSSGFGEGLC
>Sgl55090 E3_adaptor/Cullin_RING/SCF/F-box 16 0.0
MDSWSALPPDLLVSIAERLESRSHIINFRAVCQSWRSAVSTSLLTPTNILSSLFPYKGII
FNNNPSSILVASSVSLLQSSVNPKFEPWLVTVEEFNPGKLLIRAPLSRVVYRGLSSNTNL
DLSNINVLELGRFYTFRRVDKLEEMFSEKRLSEYDNKVVLFVNPNCEKNNNPSIDDCTLI
ELYDQVDHLSVTRLKNGYKHQVSFKGREFDDVVNFNGRIYAVDFLGRLCYMEYDSLEMLS
VTESPLPGCSRSNYKKRLAVLDEELYVVYRRCQISDNEGGAFKVFKLNEAEEKWDELDGV
GVDKILFVTFDGCFFVSVKDIPGWKGNCIVFRRGSFPEYSGIRSFDCKIFESWHLHRDVA
VFYFQNGDCKPLVTCSGYSGIFTPPSWIFYERIKTNSSTR
>Sgl55137 UBD/Alpha-Helix/UBA 47.6 0.6
MASSVVIKVKYEDTLRRFNVSINGEQHFDLNMEGLRLKICSLFNFPSNANFSLTYRDEDN
DLVTLVDDEDLHDVVRQGLNPVRITVDLKTNMTAPTPVAASAASSTPRESSPIDSQQKFV
PNIPETLNSVPEPLRVAVSKISTELTSKAALASPLLGELMDGLSKMGQSYLNASHSDCGT
TNVGGHAEGSAGSKQDSPSEKVDTLINEGIKHNDIKSFSSLFQSPESIQATREAEPKQPS
PSNCSSHKSKYANSGFCSHKLSTSKCKKKKEIIDYSAGKSGVNEESIKNLNASMKNHASS
KRETSNPNVRSFQFGGNFLGSNPPLGSPIPYNWKPEPFIYKADPMGLVFHKGIRCDGCGV
LPITGPRFKSKVKRDYDLCSICFGRMGNNFDYTRLDRPLFGIHALHPKATKGRTTKFCTT
KDSTDKPFRPVPVTLEDFPLLEQVNGIRARSRLDSRFIKDVNVLDGTVMAPLTPFTKIWR
MRNNGTLSWQHGLKLLWIGGVRFSSSDSVEIELPVNGLNNGEEVDIAVDFVSPELPGQYV
SYWRMADPSGHSFGHRVWVSIQVDASVDLTIQSSSNLNLNLLPSTDGALDSQVLDTSEPA
NVETGDSGFPSMDEQIGDLNFPINDDLLVASDVLCPALAASSSSATSSIRADNGATPEAS
IVSNPDVAADGIHESPSAPPANLYPVINTSDAPSTSCSTEKNDENNLVQSQGKAAVEETL
LKELEDMGFKEVELNKKVLRGNNYDLEQSVDDLCEVSEWDPILEDLQEMGFEDKETNKKL
LVKNNGSIMRVVMDLIAGETPQNSN
>Sgl55140 E3_adaptor/Cullin_RING/SCF/F-box 16.1 0.0
MDALDTDCCILPEDLFPDILSRLPVRDLLRFRCVSRSWRALIDNPSFIRTHHNAQYVLHK
AHGFLPLFLWKRTLTIQGHLLNCYLLSKHQGNDTVLNLTSELKHDTISITPNDPDLLFNI
ECRGSANGIICLDISAIDKRWSGKDFFFCGLWNPASREFKVVDYPHVPDQRTPGECYVVA
FVFDPISSDFKIMVETHVASDISVVYMVYTLSTNSWNRVCEPSLLGATAFASLPKMGSCF
NGVYYWTARLMKENENQLFRILSYNFGTEMFRLSDPPQGALSFINRSEVAWNIGLYKECL
ALFLTESVLQVGGTSVEIWVVSEFGEDFGIPLAWQCLISIKPIFECYSCFGAQRMTGDLL
FIMDGGDSCLYSLTTGKIRRLGISFHMCFEYVESLFPLSKRVIMR
>Sgl55142 E3_adaptor/Cullin_RING/SCF/F-box 15.2 0.0
MDAVDTDCILPEDLFPDILFRLPVRDLLRFRCVSRSWRALIDNPSFIRTHHNAQYNLHKA
HAVLPLFLWNRNLLNCYLLSKQQGNDTILNLTSELQHDTISITPDDPDLLFNICCRGSAN
GIICLQIYAIDKRWSGKDFFSCGLWNPASREFKVVDYPNVPDQHTLGECYVVAFVFDPIS
SDFKIMVETHVVSDISVVYMVYTLSTNSWNRVCEPSLLGATAFASLPKMGSCFNGVYYWT
ASLMKENEHQLFRILSYNFGTEMFRFSDPPQGALSFINRSDKVVWNIGLYKECPALFLTE
SVLQVGETSVEIWVVSEFGEDFGIPLAWQCLISIKPIFECYSCFGAQRMTGDLLFLMHGG
DSCLYNLTTGKIRRLGISFTMCFEYVESLFPLSRRVIMR
>Sgl55143 E3_adaptor/Cullin_RING/SCF/F-box 17.1 0.0
MDALDKDCILPEDLFLDILSRLPVRNLLRFRCVSRSWRSLIDNSSFIRTHHNAQYAMHKA
NGVLPLLLWKHTSTIQGRHLLNCYLLSKQQGNDTILNLSSEIQHDTISITPDDPDLLFNI
ECRGSANGIICLDISAIDKRLSGKDSFFCGLWNPASREFKVVDYPHVPDQSTPGECYVVA
FVFDPISSDFKIMVETHVASDISVVYMVYTLSTNSWNRVCEPSLLGATAFAYLPRMGSCF
NGVYYWTARLMKENEPQLFRILSYNFGTEMFRFSDPPQGALSFANRGDVVWKIGLYKEYL
ALFLMESGLQVGGTSVEIWVVSEFGEDFGIPLAWQCLISIKPNFECYSCFGAQRMTGDLL
FVMHGGDSCLYSLTTGKIRRRRFSRRCLRLWQASNWRCDLKFVTLVPTTQFYKPLELNFS
DVRTNSGDGLIRRLRLLELILIGIGTSIGAGIFVVTGTVGRDVGPAWSFGDLKPGTEVKL
TNRFGKEMLMPKDPNATIIMEKPHS
>Sgl55144 E3_adaptor/Cullin_RING/SCF/F-box 48.6 0.0
MDALDTDCILPEDLFLDILSRLPVRDLLRFRCVSRSWRALIDNPSFIRTHHNTQYVMHKA
HGVLPLFLWNRNLRNCYLLSKQQGNDTILNLTSELQHDTISITPDDPDLLFHIDCRGSAN
GIICLHIYAIDKRWSGKDFFSCGLWNPASREFKVVDYPHVPDQRTPGECYVVAFVFDPIS
SDFKIMVETHVASDISVVYMVYTLSTNSWNRVCEPSLLGATAFAYLPKMGSCFNGVYYWT
ARLMKENENQLFRILSYNFGTEMFRFSDPPQGALSFANRGDVVWNIGLYKECLALFLTES
VLQAVRLLESIGNKNSAISKIISRGRAVMDAVDTECILPEDLFSDILSRLPVRDLLRFRC
VSRSWRALIDNPSFIRTHHNAQYVLHKAHGVLPLFLWNRNLRNCYLLSKQQGNDTILNLT
SELQHDTISITPDDPDLLFHIDCRGSANGIICLHIYAIDKRWSGKDFFSCGLWNPASREF
KVVDYPHVPDQRTPGECYVVAFVFDPISSDFKIMVETHVASDISVVYMVYTLSTNSWNRV
CEPSLLGATAFAYLPKMGSCFNGVYYWTARLMKENENQLFRILSYNFGTEMFRFSDPPQG
ALSFANRGDVVWNIGLYKECLALFLTESVLQAEAGAVMDAVDTDCILPDDLFPDILSRLP
VRDLLRFRCVSRSWRALIDNPSFIRTHHNAQYVLHKAHGVLPLFLWKRTSTIQGHLLLNC
YLLSKQQGNDTILNLSSEIQHDTISITPDDPDLSFNIECQGSANGIICLRIYAIDMRRSG
KDFFSCGLWNPASREFKVVDYPNVPDQHTPGECYVVAFVFDPISSDFKIMVETHVVSDIS
VVYMVYTLSTNSWNRVCEPSLLGATAFASLPKMGSCFNGVYYWTASLMKENEHQLFRILS
YNFGTEMFRFSDPPQGALSFANRGDVVWNIGLYKECLALFLTESVLQMGKFSVEIWVVSE
FGEDFGIPLAWQCLISIKPVFECYSCFGTQRMTGDLLFLMHRGDSCLYSLTTGKIRRLGI
CFNTCFEYVESLFPLSRRVMR
>Sgl55167 E3_adaptor/Cullin_RING/SCF/F-box 21.7 0.1
MANIAPTKDSKEKKSNRSSPSEAKSHSSYWLPEDLIVEILVRLPLKSLIQFQTVCKRWKS
LIKNPKFAKTQLHYSNQHHLPSLQLIFQYNSVLASYIDLNDYLDNPTKANEFEPKFVELS
SQPFQKNDYDYLIVGSSNGIICFYLFKDNKLCLWNPIIHETRFISLPPNRKDECCRQDIL
FSAFGYAPSIDDYKIVLLIKKNKYRRDGSFIVYSLRRDNWSEYDHQFSKLQYFHDWFRIC
QRFGRRVEDVVFNDALHFDMGELGSCEPSYIVKFDMVKECFEKVVDLPRVQYYSYWNTTK
MVVTEDSKTWYYQPYYEKSYRTDIDTDTDATVVIKRQVVEVFKLLDNNSWEMKFVYQGSW
EDKDGRELYLIRISNNGKILLFKEMTCGPWLIGKLHILDLRHGEPSFIQVNNEDNPPLET
FPAHKYAKPNSASYVPSLVSPYYSC
>Sgl55168 E3_adaptor/Cullin_RING/SCF/F-box 21.7 0.1
MANIAPTKDSKEKKSNRSSPSEAKSHSSYWLPEDLIVEILVRLPLKSLIQFQTVCKRWKS
LIKNPKFAKTQLHHSNQHHLPSLQLIFQYNSVLASYIDLNDYLDNPTKANESEPKFVELS
SQPFQKNDYDYLIVGSSNGIICFYLFKDNKLCLWNPIIHETRFISLPPNRKDECCRQDIL
FSAFGYAPSIDDYKIVLLIKKNKYRRDGSFIVYSLRRDNWSEYDHQFSKLQYFHDWFRIC
QRFGRRVEDVVFNDALHFDMGELGSCEPSYIVKFDMVKECFEKVVDLPRVQYYSYWDTTK
MVVTEDSKTWYYQPYYEKSYRTDIDTDTDTDATVVIKRQVVEVFKLLDNNSWEMKFVYQG
SWEDKDGRELYLIRISNNGKVLLFKEMTCGPWLIGKLHILDLRHGEPSFIQVNNEDNPPL
ETFPAHKYAKPNSASYVPSLVSPYYSC
>Sgl55169 E3_adaptor/Cullin_RING/SCF/F-box 16.9 0.0
MEKTGEKKKQENFLSFSYLPNEVIFDILVRVPAKTLLQSKTICKEWKSIITSPLFARTQF
RFFKQQFHLPSHYLLSRYVTSFAVDLNRNDDFRHNITAKELENQVMPLSSKYFKLTSAKD
VLLSSCHGIMCIYYVEKNNLLLWNPTIDECRFVSLPYENYKVHRFYYVGFGYASSIDDYK
IVIAIEYLAHNCINYRKSISVYSLRRNEWRELDFEYCNSIIPELYSKLGYHTDRKNAMRV
ESIVMNDALHWVIGRHKCNKNMKFFLYKFDLVNECFEKVVDLNRISVLTDDEEDDKLAPR
QIEIGVSENNRLMIYKLYSDIPTTRTDHISKTMAIKRDVVKAWEMVDQYDYKSWKTKFHY
VGRWDDMRDDHDLVQITGDGKVVIIGGSFAEHNNRIELQKLQIQKVDFYAAHYVPSLVSP
NNF
>Sgl55203 ULD/UDP/UFD/UBX 54.9 0.1
MSSSNMRDNPRTRSGDNPSCSGIVRRMVNLPRSILGGLRGMGNGIDFMGSRERRNQIFPP
APPPPPPPPPFLPPPQFPVFPPHYEPQTALVNEEWTFLNNFEQNYGVSHPFFYACRFIQA
LKIAQDEKRFVFLYLHSPDHPFTAGFCSQTLSSEIVVQFLDANFVSWGAIADKGEGLQMS
GILRPASFPFSAVIAPTPAPGDNIAVLQQIEGPVSPAELLEILQSTLEEQGVAFGSTRAK
EEDRRREDRRLREEQDAAYVAALKLDQEREKLRNIPPQQTVQKSEPPTLASNRGISDWLR
KTPNQVKESAATNRENLHNDSLNKGKNQVTQILIRFPNGERKEHSFSVTDKVQAIYNYID
SLRLPGIGNYRLVSSFPRKVYGVDETDMTLQEVGLYPRASLFLDLL
>Sgl55213 E3_adaptor/Cullin_RING/DCX/DWD 45.4 7.5
MDFGHCCLEGNTDAVEFCPHDGFQNILAVATYTLQEGDPPSRLGSISLFDVSSKSRSFNQ
VGIVETAGIFDMKWNPAGCASSPLLAQADADGCLRIHELECSSSGPTLTGALLKEKCGIQ
ISSSMCLWLDWNPLATSLAVGLSDGCVSIASLAVSQLVEDQQWKGHDFEVWTATFDTHQP
AVLYTGSDDCKFLGWDLRVGSSMPAFQNSKAHTMGVCCIVKNPSDPYSLLTGSYDEHLRV
WDVRSISKPVNETSISLGGGVWRIKYHPFVKDLVLAACMHNGFSIVKIDSDSPKVIETYN
KHESLAYGADWQRYMPDNQEGKKEDNAVATCSFYDRMLRVWIPEADVLA
>Sgl55240 E3_activity/RING/RING 33.8 5.9
MAIRGVDFKWYDGFFLSMLATSVVIVGINWKRYHLCTYPLHVWIVVDYTTVFVFRLLMFV
DNGLAAGMGLDFGWQQRYARFCGRIAVLSVLTLVLYPFLWGWTVVGSLWFTKGKDCLPEE
GQKWGFLIWLMFSYAGLCCIAFICVGKWLLRRQTHMARAQQGGVPISEYRVLVDMIRVPD
WAFEAAGQEMRGMGQDAATYHPGLYLTTAQREAVEALIQELPKFRLKAVPTDCSECPICL
EEFRVGNEVRGLPCAHNFHVECIDQWLRLNVKCPRCRCSVFPNLDLSAISNLRAESEQER
TSATVVTTAQYVRAQTPSQSYRLRLQGLLRPVRSSENVGSGNESENALEVAENGGIFTNP
GPARVNPSPYHVEHDVAAPSSVSSH
>Sgl55249 E3_activity/RING/RING 29.4 12.2
MDIIISIFLLFVGIAILVIIHICIVGRAFSREFFGSDGLPIIKGAGLSVQDLKKLPAFEY
SQSQQQQQQQQTEDNSCNVKEHSIVECSVCLEPFKRGDQCRLLPNCHHFFHAYCVDAWLM
KSPFCPICRTCTTFVATMLSPKVGSADMDMAHQEGNNHHHVLSATTATSYVVAEEVC
>Sgl55251 E3_activity/RING/U-box 105.3 0.1
MIRKIDPDNRRILNFPAVRPCESISPAILLTSLITLSTEITTFKSKFFPSQKRLIREVIR
QIVILQFFFEEIRDQQPRFTKSLVLCLSELHYALQKMHFLLQDCTREGCRLYILMKSQFI
AGQFGVLINSIGTSLDILRLNSLEINSEVKDLVELLAKQAQKARVEVNLNDQCAMERVIL
ILNQFENEFEPERGLIKRVMDYLGIYTWGDCNKEVKFLEEELNNVEDEQEREITLISNLL
GLMCYCRGVIFENLDENEEIIGKSVGELLNCLNPEDFRCPISLELMMDPVTVSTGQTYDR
GSIQKWLKSGHLLCPKTGEKLKTTEVVPNTALKKLIHQFCTDNGISISKPGRRNKDTAKA
GTSPSPASREAMRFLAQFLAARLTYGADEQKNKAAYEIRLLTKSSVFNRSTLIEMGNVPL
LLDLLTSTDANTQENAIAALLKLSKHYKGQKSIIEEGGLMLVIQVLRRGLKIESRQIAAA
TIFYLSSVDKYRRLIGSTREGIPGLIELIKYGTMCGKKNAIAAIFGLLLYHRNHEKTLEA
GIVPTLIDLLSTIERSDLLADSLAVLACLAEKVDGSIAILQTSALPLIIGMVKSSISKAG
KEYCVSILTSLCNNGGDEVVAILAKEQALMPCLYALVTDGSAYASKKARSLIDMLQKFQE
SSSSNWAAASKVHKERFVDAEFS
>Sgl55262 E3_activity/RING/RING 31.3 9.3
MSNLATQFKESDSISISPSPTSPFQSPSNSNNSPNSSSSSNNSNKISPVILLIIVVLAMI
FFVAGILHLLIRYLMKRPSFYSSSSSVSNSRNPENNNSNSGALQRQLQQLFRLHDSGLDQ
ALIDALPVFYYKDIMGLKEPFDCAVCLCEFSDQDKLRLLPLCSHAFHISCIDTWLLSNST
CPLCRGSLLGSELENQEFSLEFWRALSFGRSINCENSFHFGNSFNNSSHSHSVKPTIMEE
NASERRVFSVRLGKFRNVDDRGDTNNITNKVYESGETSGRGSGREGGGGGVDGSSSRQLD
ARRCYSLGSYQYVVADSNLQVALSTDVDVSGTKIEKLMGQCGGNSMVEGDIEGKKISRRN
KRDSFSVSKIWLWSKKSKFPGSSENNANNHGPPPLNVVLPLSTRDHLDFP
>Sgl55263 UBD/UBC-like/UBD_UBC 99.2 0.0
MSSPSKRREMDVMKLMMSDYSVETINDGLNEFYVMFNGPKESLYEGGVWKVHVQLPDAYP
YKSPSIGFVNKIFHPNVDELSGSVCLDVINQSWSPMFDLLNVFEVFLPQLLLYPNASDPL
NSDAASLMMKDRQQYDQKVKEYCDRYAKKENANGSAAEDESDEEDISDGNCTSSDDEIAG
KADP
>Sgl55268 E3_adaptor/Cullin_RING/SCF/F-box 16.8 0.0
MRNRKKGTPLPEHYHFPPELLNEVLGRLPPKTLLRFRCVCKSWCSLIDSPDFIDFHLHLY
PNNCNKTQLFVKEKVPKTCYETVITIRRSDTFRKVSQCVKIPNTVMGCRSNMVHGLMLMK
SICDELSLWNPSIQKLVRLPFCPFKFDYADARCMLGFSPLSNDYKVIFCKLIDTTAFEVG
IAVYSLRGECWRVKNNRLTVSKCCFDELKSRRGAIFVQGFVYYRPNQCWWYNKDTELLCF
DFDAEDFSFLKLPEMEVEMYRMIFAFGGSLGLLGVSSVRTCIWKLEKNDGVEPWRPYWNG
DTNLDVYAFYKDSSNNYKETMYIEHTGKLLLQSMKKLIAYDFRSNQTKRLGKSIPLRYVD
TYVESLVLHKGHNDAASTSHG
>Sgl55271 E3_adaptor/Cullin_RING/SCF/F-box 13.8 0.0
MRNRKSRKQLPEHYHFPSDLWSDVFSRLTPKTLLQLRCVCKSWCSLIDSLDFIDCHLKFN
PRNCAKTQLLVEERVPKTRSDTKFTVRRSDTFRKIAQLVLPSKFHMVYKSPTIHGLMLIE
NSRENELCLWNPSIRKSVLLPPSPLKFDFWNYSCLLGFAPSSKDYKVFVCKLVDAKAFEC
AIAVYSLRNHSWSVKHNSLKVPRWCYEELKCQKGTAFVQGVVYWRPTYYRRHNDSIELFS
FDFDNEEFRYLKLPEMEEDMYRFIFELGGSLAVLGISSVRSCIWVMEKKGEIELWRHYWQ
GDTNSDVFNFFADFTYNEFELLFDEDIGRFFIQSNRKLMAYNIGSNQAQWWAKYVRLRYA
ETYVESLVLHKGYEGVALTFHE
>Sgl55289 E3_adaptor/Cullin_RING/SCF/F-box 14.7 0.0
MSFLDTKMEIDMIPSKNLLPELWMEIFSKLPAKILVKLRCVSKSWRSMIDNPSFISMHMS
QFKNNLNKHFLLCFETHSLLDEDEFELKIRVRTMGKFRKREQILSVTFSAVDYLIDYKGY
VDGLLLFGRYYEGSYDLFLLNPSIRKSIVLPQIPPSPAGRAETVIGFDPVKNDYKVVMIL
FPIRLVELSFPDSILVYEFRTGVWRFNTGIEIPDQWYLGESVLTRGVVHWLSFNLSMDLP
LPKNFTHIVSFNFGSETFSYTELPGIEVMIAKKSLTPFFLAILLPCWIFLLMSWMFTMQI
FAYG
>Sgl55292 E3_activity/RING/U-box 53.5 0.3
MGGKGNGKFLKLNFSFYKNSPSRSCSTPPQPQSQQPPPEYICPICNTLLSDPVVVGSGHT
IDRLCLEVCEAHNFSPKLPDGTRPDFTTKIPNLALRSAIPTWCTKNGVTLPTKDKASIER
IVIGMLEKDEQQNRDSSNNNNQNDELKKIRPSERFLLDSVTDKPDPDYSHAVTELTHRVN
RFDSSTSSEESVIAAPVSPLTPLPFTTRPACWSPFHDHNNNTSSSSETLNSDEMMMMNSN
SNPNFTISEDDEFIAKFKSCDPFNQEQGAASLRKATRTDEKARINLCTPRLLLAIGSLLF
SNYEKVQINAIAALVNLSLAKPNKIKIVRSGIVPTVVQLLKGRLSETQEHAAGLIFSLSL
EEKNRTAIGVLGALPPLLNSLLRSESERTRSDSALALYNLSLDHSNRLKLVKQLNAVTPL
LAVLRQEKEAISGRVLLVLYQLAASAEGKAAMLDGNAVEHLVAMLRKGRDEFESESTREN
CVAVLYALSHGSMRFKALAKEARAVEVIKEVEENGSERAKEKARRILTMLKGRRESGDED
VDWEAILEGGISGGDGGGGVSRARYRAGVSPGVGKTTEF
>Sgl55360 E3_adaptor/Cullin_RING/SCF/F-box 16 0.0
MGGIFSLKSSGDRNCQNYEGTASGCKRQRVTTCFEHTTRLVPSLPNEISLQILARVPRVY
YLQLKLVSRSWKEALSTSEIYKLRREFKMTEEWLFILSRVEENLLWCALDPVSQKWQKLP
PMPHDSAHDESKRGLALVQMWNALGSRGKIADAIRGWLGGGDPLDEIPFCGCSIGAVNGC
LYVVGGLSKTSALSCVWRYDPILNSWNEVSPMLYGRAYSKTGVINNKLYVVGGVSRHRGG
LTPLQSAEVFDPETEQWSEVPSMPFSKAQIMPTAFLADLLKPIATGLTAYKGKLYVPQSL
YCWPFFVDAGGEIYDPETNSWNEMPIGMGEGWPAKQAGTKLSVVVDEELYALDLSGSLDN
AKVKVYDHRDDSWKIVSAEVPMTHDQADAESPYLLAAFRGKLHVIIKDGNSDITVLQATA
GSLAQPSQSNQSSSRSSSSGGSVTSSPPAVTWNVIASTRAGPAELVSCQILRI
>Sgl55361 E3_adaptor/Cullin_RING/SCF/F-box 15.9 0.0
MKLRLRSLETKQTQNIEVPNNCNLQQLKQIIILQLFSSSSTIQQNLTLSLNGKEQLFGSS
PEESIQSIGVTSGDLIYYSQNPFAFSSQIPNFSHVQLENENSREINIINCDKGDNLMNTH
EVESGKSDELNNLDVEIRDLMEGTSNLVDSGDHSDDLGKTQVLELCKDDELIGSSSRIRE
SSDYDEENSTELMEESNDQEVDDESEVEGNCRFSVPSFLKKIFVKEVRDAADNGSDHKLL
VIAVHAVLMESGFVVYDPILRKKADSFRLADEWPSLAFGITLYYTLPEAPTSEGVETVVL
KFQSLGKFMTIYGSLPKKGFRVHRVCLDEPLFVPAFSYIWKKSDYTGSENEIGGSRKLFP
NHEIFEFWKIVKDGLAYPLLIDLCEQMGLVSPPCLMRLPTELKLKILEFLPAIDVARVEC
VCSELRFVASNNDLWKLKYEEEFDCAVASQRECQWKARFSSLWDIRKRRKRVCMPPLRWQ
EPPQFRPLFPGRRNRNRFGPPFIIGGDYDRLPAFGIPQHPGRRILGGIVTLEGLVESESL
IDSLS
>Sgl55448 E3_activity/HECT 348.7 0.0
METRSRKRAEASSSAPSSSSAGPTTRAAKRTRFSSANTATATPTTRSRSRTNISLSSATA
MDESSSRGGRRGKNHHGSDKDNDKNLTSASSALQGLLRKLGAGLDDLLPSSAMGSASSSS
HQNGRLKKILAGLRADGEDGKQVEALTQFTFSVDSFVPVLVGLLNHESNPDIMLLAARAI
THLVDVLPSSCAAVVHYGAVNCFCARLLTIEYMDLAEQSLQALKKISQEHPTACLRAGAL
MAVLSYLDFFSTGVQRVALATAANMCKKLPSDAADFVMEAVPHLTNLLQYHDAKVLEHAS
VCLTRIVEAFASFPDKLDELCNHGLVTQAASLISTSNSGGGQASLSTSTYTGLVRLLATC
ASGSTVGAKTLLLLGISGILKDILAGSGLVGNMSVSPALSRPPEQIFEIVNLANELLPPL
PQGTISLPTSSNLFVRGPLFKKSPMSSSSKPDEINGNVQDVSAREKLLNEQPELLQQFGM
DLLPVLIQIHGSSVNGPVRHKCLSVIGKLMFFSNSDMISKFNNSTNISSFLAGVLAWKDP
QVLVPALQIAEILMEKLPETFSKMFVREGVVHAVDSLITAPSTHAATTEKDTESTPGSSA
RARRLRRRSGNQHQDTNSVEESKSTVSVTVGSPPTSVELPTVNSNLRTTVSGCAKSFKDK
YFPSDPGAVDVGVSDDLLHLKNLCAKLNAGVEEQKLKVKGKSKTAGAYIADFSAGKEESL
VGIVSEMLEELSKGDGVSTFEFIGSGVVATLLNYFSCGYFNKEKISEANLPKLRQQALKR
YKLFISVALLTGVDGGDLTPMTVLVQKLQNALSSLERFPVVLSHSARSSGGSARLSSGLS
ALSQPFKLRLCRAPGEKALRDYSNTVVLIDPLASLAAVEDFLWPRVQRSESGQKPSTSVG
NSESGPSPTGAGASSPSAFTPATSTRRQSARSRSGLNIGDTSRKESLQDKTNSASKGKGK
AILKPAAEESKGPQTRNAARRRAASDKDAQLKSPTGESSSEDEDLEMSPVDIDDALVIED
DDDISDDDEDDHDDVLRDDTLPTCMAEKVHDVKLSDSAEDSAAAPATSDSQNNPASGSSS
RAATVRGSDSTDFRSGSSFGSRGAMSFAAAAMAGLASNGRGIRGGRDRHGRPLGGSSDPP
RLVFSAGGKQLNPNLTIYQAIQRQLVTDEEEDERYNGNDPVASDGSRLWSDIYTITYQKA
DSQVEKSHGTVSSASPSKSTKSGSVSSSNVDASSHRSPLDSILQGELPCDMEKNNPTYNI
LSLLRVLEGLNQLAPRLRVQTASDKFSEGMILSLNELSATGSRVPSSEFVNSKLTPKLAR
QIQDALALCSGSLPSWCYQLTKACPFLFPFETRRQFFYSTAFGLSRALYRLQQQQGDGHG
SNEREVRVGRLQRQKVRVSRNRILDSAAKVMEMYSSQKAVLEVEYFGEVGTGLGPTLEFY
TLLSHDLQKVDLGMWRSNNSFDKSSMEIDSDEQTKDGKSEDASRLSSRANTNIVQSPLGL
FPRPWSPNADSSEGGQFSKVIEHFRLLGRVMAKALQDGRLLDLPLSTAFYKHVLGQELDL
HDILSFDPEVGKTLRELQALVCRKQYLESIGGDHPDVIAELCFRGTPIEDLCLDFTLPGY
PDYVLKPGDENVNINNLEEYISLVVDATVKSGIVKQMEAFRAGFNQVFDVTSLQIFSPDE
IDCLLCGRRELWKPDALVDHIKFDHGYTAKSPAITNLLEIMGEFTPEQQRAFCQFVTGAP
RLPPGGLAVLNPKLTIVRKHSSSATAAANGTGPSESADDDLPSVMTCANYLKLPPYSTKE
IMYKKLLYAINEGQGSFDLS
>Sgl55456 UBD/UBC-like/UBD_UBC 236.9 0.0
MASRRILKELKELERDPPSSCSAGPVAEDMFHWQATIYGPHESPYAGGVFLVNIHFPPDY
PFKPPKVAFKTKVFHPNINSNGSICLDILKEQWSPALTISKVLLSICSLLTDPNPDDPLV
PEFAHLYKTDRNAYESMARSWTQKYAMV
>Sgl55460 E3_adaptor/Cullin_RING/DCX/DWD 118.3 7.8
MGEDEEMPMTEEQLKEEFEVWKKNTPILYDLVLFNPLEWPSLTVQWLPSSPVINSDSSLA
VHQLILGTHTSDHSPNFLMVADVHLPHKNTPCSSVPKVEIVKKFQVDGEVNRAVCMPQKQ
NLVAAKTSGLEVYVYDITKEPSSGVCDPEVRLRGHEKEGYGLSWNPLKEGYLLSGSYDCR
ICLWDVSSMPQSKVLDSMSVFQAHESIVEHVAWHTKNESMFGSVGDDGKLMIWDLRSDKP
QHSVEAHEKEVNYLSFNSFNEWIVATASSDTTIGLFDLRKLTTPLHSLSSHTEEVFQVEW
DPNHETVLASSSDDRRLMVWDLNRVGDEQLEGEAQDGPPELLFSHGGHKAKISDFSWNKN
EPWMISSVADDNTVQVWQMAESICCDEEEIPAE
>Sgl55468 E3_adaptor/Cullin_RING/SCF/SKP1 112.4 1.0
MASAPKKITLKSSDNEEFEVDEVVALESQTIKHMIEDDCADNAIPLPNVTGKILSKVIEY
CKKHVEAAAAKSSSEDRSSSNSAADDELKNWDTEFVKVDQNTLFDLILAANYLNIKSLLD
LTCQTVADMIKGKTPEEIRKTFNIKNDFTPEEEEEVRRENQWAFE
>Sgl55480 E2/UBC 87.2 0.0
METDQNGALNGVEGATSVSGDSFLSGGVNVEGSSNCNVKNEGNPLTAKLESDKHIYRQDV
VKCKDGSMIGVVTEVAGDSDSESESESESGITDDEDEDDKEEEEEGEEVEGESGEGKEED
GEEKDDDRVRDGEDNESCDDNKSDGNNKRDPLTGDQVRVLWMDDSEKMHHRNELTVVDRG
FLHGDYVASALNPSGQVGLVVDVNIIVDLWSTDGNVVKDVSARELKRVRDIVVGDYVVSG
PWLGRVDDVLDNVNVLFDDGSVCKVARAEPMRLRPIAKNLLEDGHCPYHPGQRVRASSSS
VFKNARWLSGSWKANRLEGTVMKVTVGSVYVHWLASAGFGPNSSTSPPEEQSPKNLKLLS
CFAHANWQLGDWCLHPAIKWFSSIPLDKGLSNLRLNESVPCASVSDADELLPEESNVHVE
LMDHDAASTSESVDGNGKNNASPESSSCGSSLSISKDTVHESWNNHRKKLRKVVVKRDKK
ARKKEENFERALLIVNTKTTVDVAWQDGTVQHGVDSTLLIPIESPGDHDFVAEQYVIEKV
ADDGEEVPEIRRVGVVKSVDAKEKTACVKWLKQVARPEEPREFEKEEVVSVYELEGHHDY
DYCYGDVVVRLSPVSIMEALAFSDPKVSNVPNGGKGESETNYNDKEGEASDEVASNELSN
LSWVGNITGLKNGDIEVTWADGMVSTVGPQAVYVVGRDDDDSMVAGSEISDDAASWETVE
DDEMDSLENTKKESPPEGTEAHPDSVEDIVVTEHDPGNNGPLFAAIGYVTRFASGIFSRG
RKDGDSFDSEDSVGTRMQPEGEIVLSNERTSSNVDNSLDICANDTGSRQINLDKSDEPAE
VEAAKCSQMADVLGHLNHKESNPSLCADDNICSFKRFDTAKDPVDHFFLGANTPSNSGRK
WLKKVQRDWNILQNNLPDGIYVRVYEDRMDLLRAVIVGAYGTPYQDGLFFFDFHLPPEYP
DVPPSAHYHSGGWRINPNLYEEGKVCLSLLNTWTGRGNEVWDPQSSSILQVLVSLQGLVL
NSKPYFNEAGYDKQVGTAEGEKNSLSYNENAFLLSCKTVMYLVRKPPKDFEDLVKEHFRQ
RGCLILKACDAYMKGYLIGSLAKDASVTERIVVAVQESVLYCQFNSATAQVFGSKFRSNY
HFRLTKMCRIEIS
>Sgl55514 E3_adaptor/Cullin_RING/DCX/DWD 72.4 7.9
MGVKRPRSAVVDVWQREVGQISSRNFAHRLAASEDLVLRLDILRKLVKHRGCVNTVSFNS
SGDILVSGSDDRKVILWDWEVGHAKLSFHSGHVNNVFQAKMLPYSDDHNIVTCAADGKVR
LAQILEGGHVETSLLGSHKGRAHRLAIDPGSPHVFYSCGEDGLVQHFDLRTKDCTELFTC
HSTFGRRRNSSFVHLNAIAIDPRSPNLFAVGGSDEYTRLYDIRRYKWDGSSDFGQPINFY
CPEHLIGSKQVEITGLAFSDKSELLVSYNNENIYLFTKDMGWGPNFAPSSVSTCSDTAYE
PEDDDPSEATKSVLDTNKKPIPQVYKGHHNCDTVKGVSFCGPKNDYVVSGSDCGRIFIWR
KKDGELIRVMEADRQVVNCIEAHPHTAVLASSGIESDIKIWTPKAEERATLPANIYEVKC
GRPYFFDSDEDETSFSDDDGDDDDSEDDEEMYEYDNNSYDDEDDDYDDYYDDDDVDEDDD
EVEDEDDDDYDGGGSGGGGGGGGDINLRPRQRGLMNGASSPQELIMQLFSLQNRRFSSPE
PEDSEENSGLRQDFIDLMLSMSRHSDDSSDDGAGDESGPEDFYS
>Sgl55519 E3_adaptor/Cullin_RING/SCF/F-box 16.3 0.0
MEEGGGGEEEEEKMALEQLPSTLLATIIAKLDMASICSVASTCRTFNSCASHILTFLPTV
HLLDVAPSMDLLVPLLPQNPYLTSLKVDCCRLDDTAINRLIRPSLHELFLHNCGDFSGRL
LSEIGGHCHNLRSLYLGSVGDKRGRAVHISDLEELLKGCAELETLNLMFDVSTFLRHNFA
RAWTMASANLTSLEIGYISSVMVTELLSPTPGPNQFLQQEEPPVLPNLQKLCLSVDYITD
TMINTISQNLTSLIHLDLRDAPIIEPRVTFDLTNNGLQQINQHGKLKHLSLVRSQEFLIT
YFRRVNDLGILLMSDKCASMESICLGGFCRVTDTGFRAILHACTNLYKIKISHGTQLTDL
VFHDISATPLSLTHVGLRWCNLLTNLAITRLASNLDLTVLDLRDCRSLGDESVMAISFLP
KLKTLLLDGSDISDVGMSHLKPRVASSLISLSVRGCKRLTDKCIPALFCSSLKPVLQELD
LSNLPNLSDNGVLLLAKSRVRICELRMRQCPLIGDTSVMALASMQVDDNKWHGNCLRLLD
LYNCGRISALSFRWLKKPYFPRLKWLGVTGSVNRDMVDALARSRPFLHVAGRGEELGTGQ
WDHADGFYIHDYEEMDELERFILEGDEEISDEEMAEGELDEEQEE
>Sgl55594 ULD/UDP/UBQ/UBQ_PIM 84.4 0.0
MGAEGDSSDTNVAVTEEVSVNIRCSNGSKFSVKTTLDSNVSAFKSLVAQNCDVPAEQQRL
IYKGRILKDDQTLESYGLQADHTIHMVRGFAASASTAPSGTTAASDTTPAAAQAAAPAPA
ANPAEGGGLGSAGLGASLFPGLGGLGGTGASGVLGAGLPDFEQMQQQLTQNPNMMREIMN
MPAIQSLMNNPDLMRNLIMSNPQMRDIIDRNPELAHILNDPSILRQTLETARNPELMREM
MRNTDRAMSNIESSPEGFNMLRRMYENVQEPFLNATTMAGEGGNNQASNPFASLLGNQGA
VGGQQTDGSQNPSTTGSETGVPNTNPLPNPWNSTGGGTQTNSAPRANSTGDTRPSPLGGL
SSLPELDRMFGGAAAGGGGVPDASMMNQVLQNPAISQMMQSMLSNPQYMNQILNMSPQLR
AMTESNPQLREMMQNSDVLRQLANPEMMQQMLTMQQSLLSAMNRPQSNQDQSPNAGAAPA
AGNANNNMGLEMLMNMFGGLGAGGLTTPENSNVPPEELYATQLTQLQEMGFFDAQENIRA
LQATRGNVNAAVERLLGNMGQ
>Sgl55618 E3_activity/RING/RING 37.8 5.9
MASLHIHRKLLPANSPDEYSSEDLTVETCLYFCHSQRNNTSPKPGFCPEACLAICPSVCH
YSLTDVPFPPPAIPNKSQNLSPLLLCMLILLASTFLLITLYILYTKLYYHFYAPNSNNSF
LQRRSRRRRRESDAGSYSVDEENRNRVVFHPFWSIPTVGLPPAEIRSIPVHKYGKEMEER
DCAVCLAEFEEGDELRVLPKCNHAFHIPCIDTWLSSHTTCPLCRSPVTSPDDDHNSDHDH
PHKAEDTSSSLTSMEGASREDDNSPAEVLSITVTGGEEVENNTNENHTENSRNKDQENPR
RVNEGSSSSSQRWSLERGAANLLSRSLSCSGKIFSSRSSNIRPSPNS
>Sgl55623 E3_adaptor/Cullin_RING/SCF/F-box 17.1 0.0
MGPLPIDIISNILARLPVKYLLRSKTVCKSWNAIISSKPFINLHLQLNSISTSDKLLLFS
TNDHSLYSLTLDSLESPATKLNFFNNNDSSFSGFGGSCNGLLLCFTNTGGSNSGVCLVNP
STLQCKMIPRLKVPKSYVCVNYGFGYDHIHDDYKVVRVINLVYGCEYTSVFNAREVMVYS
LRNNSWKFIEEKVSNYATLASRNGALVNNHLLHWVFWCISSNRHRISSFDVCSEQWGEVP
MPCYVRGNLRENPSNVDVWIMKEYGVKESWVKLLNVSNLNAIPIAYSEKFKEILFRKEKE
LSVFWYDLRRRTSRNVEICGLQDCCGVTSCIRTIVPLNCHGEIDD
>Sgl55659 E3_activity/RING/RING 20 14.5
MSEATEQNQQDQAETVCSFARKPLRNKNIRKRPSDDNEDGSEGSSMLTTNKKLAKTDNKL
CFSSGTTKRSAPAESTEDSKNMFFQYESSKEIQVQNDSKATATLETETDFSRDARAIRER
ALKLADEGLKGKNKSGEKVYKGMHNYTDYRAGFRREQTVAAEKAGGAHGPLRASSHIRVS
ARFDYQPDICKDYKETGYCGYGDSCKFMHDRGDYKSGWQMEKEWDEAEKTRKRNLALGGH
DSDEENAVNDEEDDDDALPFACFICREPFVDPVMTKCKHYFCEHCALKHHTRNKKCFVCN
QPTLGIFNTAHEIRKRIAADKKKADNN
>Sgl55685 E3_adaptor/Cullin_RING/SCF/F-box 16.8 0.0
MATFPPEIITEILSRLPVKSLLRFKIVCKFWHFLIETPNFVKLHLNLSLISNSNLHLLLY
YPYLYFAELNSHHNHLSFSTLHHPLEPRQVHLLGSCNGVICISDPSKTDTFLFNPLTKSQ
FKLPDNRIPDLSPAVILFGFGFDAKSDDYKVLRLVQGYKIGKVYYEETKVFSLKTNSWKS
VGGTSFYLFDVDCHGVLVNEALHFTVILKETKSKGHLIAKFDLHNDSFSLMEYPNYGGKG
KGTAVLTLTNLGGCLCAMVNHHKDFVLEFADLWVMKDYGKKESWFKLYRICQNQGFDSRM
QIKPIVYSKDKRKVVVEIDNLVFGWYDLESKYLEKIAPNGLPNGNIETSSFVGSLVSVGD
KLQSGGGTLPRRNNKKNDAEKFLSKGFKLRL
>Sgl55719 E3_activity/RING/RING 39.6 5.5
MFFLYESKLCMTTIIFYTCIYIPLLQIKNAICSILGFILFLHDNTLEHPEGLTPVDLVEE
ACSIDLPMSQYSDLKVSGCNTGNLEDGECDEACSVCLVEFMSEDLVSKLSKCGHIFHMEC
IEKWVERNQFTCPLCRSSFLNLDESKCHAICNDMVLSCFST
>Sgl55730 E3_activity/RING/U-box 121.5 0.6
MREKRIPIVPLEPLDAAGIQIPYYFRCPISLELMQDPVTVCTGQTYDRSSIESWVATGNT
TCPVTRAPLSDFCLIPNHTLRRLIQEWCVSNRSFGVERIPTPKQPADPSLIRSLLAQSSS
GSNPIPNRVAALRRLRGLARDSEKNRSLIASLNARDVFVSILFNSDESNSNSFDDSSELN
HEALALLASFPPSDAACASVASDPERVGYLVNLLFHPSSLDVRVNSAAVIESIIAGTKSS
DLRSFICASEQVYVGVISILTNPIPSPRALKIGVKTLFALCLSKQHRHKAVTAGAANALI
TRLTELDKCDCERALATVELLCRVPQGCAAFGAHALTVPLLVKTILKVSDRATEYAAGAL
LSLASSSERLQREAVNAGVLTQLLLLVQSDCTERAKRKAQMLLKLLRDSWPEDSIGNFSD
DFNCSDVVPF
>Sgl55733 E3_activity/RING/RING 30.3 6.7
MLGQFVPFYPQCNCFVYLVYMEYYCEKLIKAGILYIPIYGGPRHENNGFVVDRDRFGNLR
LNSDELSYEELVSLSEWIGSVTTGLSEETIMALMKRKSYECVNTNPVPGDDTCCICRVKF
FFPTGEYETGEDIGVLNCGHEFHTECIKQWLVIKNNCPICKLKGLDA
>Sgl55747 E3_activity/RING/RING 10.5 12.7
MEISPASPASYNTQIQSSNSDDKDSNDVVSIEDGEREFSRQNDDFSATSTSSTVVKRSSS
SYDDDDDEEDVCRICRNPGEPDNPLRYPCACSGSIKFVHQDCLLQWLNHSNARQCEVCKH
AFAFSPVYAEDAPVRLPFREFLLGIGKKTCHVLKFFLRLGFVLSVWLLIIPFITFWIWRL
AFVRSFSEASQLFLSHMSFTVILTDCLHGFLLSASIVFIFLGATSLRDYFRHVREAQGHD
LDREDEGDRNGARAVRRPLGQANRNLLADGNADDGGDAQGIAAAGQLIRRAENVAAQWER
QAARLEVHVDQIFDGLDDADGAEDVPFDELVGMQGPVFHLVENAFTVLASNLIFLGVVIF
APFSLGRLILHYVSWLFSSATNPVLSTVMPLTESALSLANITLKNALTTVTNLSSENSEN
LMDHMSEILQANASGLNVSPNNISTPSTSDVLKGVTAGTSRLSDVTTLAVGYMFIFSLIF
LYFGMVALIRYTKGEPLTMGRFQGIASAAENIPSLLRQFFAGMRHLMTMIKVAFLLVIEL
GVFPLMCGWWLDICTIRMFGKSMAQRVEFFSVSPLASSLVHWVVGIFYMLQISIFVSLLR
GVLRNGVLYFLRDPADPNYNPFRDLIDDPVHKHARRVLLSVAVYGSLIVMLVFLPVKLAM
RMAPSIFPLDISVSDPFTEIPADILLFQICIPFAIEHFKLRTTIKSLLRYWFTAVGWALG
LTDFLLPKPDENAVQDNGNAEAGRQDRLHGLQLGAGQQDQAQQPLLADAQNNEAHAESSD
VMEEYDGEEQSDSERYSFVFRIVLLLVVAWMTLLIFNSALIVIPVSLGRAIFNSIPMLPI
THGIKCNDLYAFTIGSYVIWTVIAGIRYTIEQVKSRRAAVLFGQIWKWCAIALKSSALLS
IWIFVIPVLIGLLFELLVIVPMRVPVDESPVFLLYQDWALGLIFLKIWTRLVMLDHMMPL
VDEGWRAKFERVREDGFSRLQGLWVLREIVLPIILKLLTALCVPYVLARGVFPVFGYPLI
VNSAVYRFAWLGCLCLSVLFFCAKRFHVWFTNLHNSIRDDRYLIGRRLHNFGEAAVERPA
EEAETISVERDAVIGLEDVGLRFRRGNPVDA
>Sgl55767 E3_activity/RING/RING 34.7 3.0
MDAEDLELSTISGEGVEVTSYAVEHATSSNNHVHRPVDDLFNVMLCYEDTRIPNNVARYL
SFTMVKERDQSDRTDIVTDVIGKLDEFDVDANVYPSVIDVVQSSCEILLKQVRDLGRRSL
AMIVKIIVFEHVVEEEDLVGIAPDEEEEPEPMMGEEEPMTAEQIARSMAESARKLKRLEG
IVIIVGNDGLDGVKIKRRDQFSTDMGPCSICFEDFEAQENNGGESDDSKHNNTGLLALPC
SHVFHNLCLLPWVYKGKGTCPNCRFNFFKNL
>Sgl55809 E3_activity/RING/RING 15.7 13.5
MDSETLASSSSTAEVPAPDAWITAYQKLLPQWNSYSLLSRLIIPITISRVNQFDAARLDV
EMSAMLKEQLVKVFSLMKPGILFQYEAELDAFLEFFIWRFSIWVDKPTPGNALMNLRYRD
ERVMEVRGKVRTGLEGPGLTAAQKMWYCIATVGGQYIWTRLQSFSAFRRWGDSEQTTLAQ
RAWLLLQHIEGFYKAASFGNLLIFLLTGKYKSLIERVLRARLVYGSPNMNRSVSFEYMNR
QLVWNEFSEMLLLLLPLLNSSSFKNLFRPFSKDKSSDSATDETFCPICQGSPSIPFIALP
CRHRYCYYCLRTRCAATPSFRCVRCSQPVTAIQRLGSSRAETSSKK
>Sgl55846 E3_adaptor/Cullin_RING/DCX/DWD 113.9 17.0
MGIQKIETGHQDTIHDFQMDYYGKRIATASSDHTIKIIGVSNNSQQHLATLSGHQGPVWQ
VSWAHPKFGSILASCSYDGKVIIWKEGNQNEWSQAHVFDDHKSSVNSIAWASHELGLCLA
SGSSDGNIMVYTMRTDGGWDSAKIDQAHPVGVTSVSWAPATAPGALVASGLHDPVQKLCS
GGCDNTVKIWKLNNGIWKMDCFPALQMHTDWVRDVAWAPNLGLPKTTIASASQDGKVIIW
TVARDGDQWEGKVLNDFKTPVWRVSWSLTGNILAVADGNNNVTLWNEAVDGIWQMVTTVD
S
>Sgl55866 ULD/UDP/UFD/PB1 57.2 0.1
METPEVSSLDLKETELTLGLPGKTVSNLEEKIVLKRRFSDTLDLNLGSHPNNSDEKKVQQ
PSSAPTNPPSKTQLVGWPPVRASRKNVMKRCKYVKVAVDGAPYLRKVDLELYSSYQELLK
ALEDMFSSFTIRNFFNDGKLMDPLNGSDYVPTYEDKDGDWMMVGDTPWKMFVESCKRLRL
MKSSEAVGLEARSSSEVD
>Sgl55872 E3_activity/RING/RING 31.6 8.9
MGTPLLVSHSETFSDRFPLLMGRLDDCEGCQHVIDIAAVNDAPSSSSNTVSVNQAESHHT
VDRPSSSTQHINSSLSSSSERINSRNSSFGVRGDSYGYTSPLNSGLWISVELVVTLAQIV
ASVVILSLSRYNSTEAPLFAWVVGYASGCLATLPILCWRLRNCSRGPERFLVQSHQSSPG
SVTTAEATASNSSFQQEEVDSHENSRIVSRSSLLRRRISVRLNGIVEHFKMALDCFFAVW
FVVGNVWIFGAHSSPAVAPKLYRLCIVFLTFSCIGYALPFLLCATIFCCLPCIISVMGIR
EDLSKPRGASIETIDALPTYKFKLKKDESINEAQICLKAHKDGILADETQDEFVLSGEDA
LCCICLATYVENDELREMPCSHLFHTECVDKWLKINASCPLCKLEIGEDRSMALSSDQNN
SRRQNASNEGDLSLTPANVS
>Sgl55890 E3_adaptor/Cullin_RING/DCX/DWD 113 18.9
MTLRLNMKRKFAQRSERVKSVDLHPTEPWILASLYSGTVVIWNYQSQTMAKSFEVSELPV
RSAKFISRKQWVVAGADDMFIRVYNFNTMDKVKVFEAHTDYIRCVAVHPSLPYVLSSSDD
MLIKLWDWDKGWVCTQIFEGHSHYVMQVTFNPKDTNTFASASLDRTIKIWNLGSPDPNFT
LDAHVKGVNCVDYFTGGDKPYLITGSDDHTAKVWDYQTKSCVQTLEGHTHNVSAVCFHPE
LPIIITGSEDGTVRIWHSTTYRLENTLNYGLERVWAIGYMKSSRRVVIGYDEGTIMVKMG
REVPVASMDNSGKIIWAKHNEIQTVDIRRVGAGYEVTDGERLPLAVKELGSCDLYPQYLK
HNPNGRFVVVCGDGEYIIYTAVAWRNRSFGSALEFVWSSEGEYAVRESTSKIKIFSKNFQ
EKKSFRPSFSAERIYGGTMLALCSNDFICFYDWADCRFIRRIDVNVKSLYWADSGDLVAI
ASDTSFYILKYNRDAVASFVDSGKPIDDQGVEDAFELLHETSERVRTGLWVGDCFIYNNS
SWRLNYCVGGEVTTMFHLDRPMYLLGYLAGQSRVYLIDKEFNVIGYTLLLSLIEYKTLVM
RGDFDRANELLPTIPKEHHNSVARFLESRNMVAEALEVATDPDFKFELAIQLGRLEVAKE
IATEVQSESKWKQLGELAMSTGKFEMAEECLKYAMDFSGMLLLYSSIGDAEGISTLASLA
KEQGKNNVAFLCLFMLGKLEECLQLLIDSNRIPEAALMARSYLPSKVSEIVALWRKDLSK
VNPKAAESLADPEEYPNLFEDWQIALAVESKVADTRGSYPPAEQYLQYADKLKIDLVEEF
KSMQVEEDQPLENGETEHEEEQEEENGADESQEEDVVVDADSNDGAVLVNVLKIQILSLF
LLNILKVSFNLLVLTVHFVV
>Sgl55956 E3_adaptor/Cullin_RING/SCF/F-box 15.2 0.0
MSIFVRLPEDAILEILLRLPVKSLQRFKCVAKSWYARISDPHFMIRHFISSNNHEFLLVS
HLHPVRRQVLSLLPSETLQNKAKHFQLPYASSSEENRSFVQISGPCNGIFCLFNSKDGAI
SLWNPATRQLKTLPKSNVEPPLTSYPFDICVGFGFDKESNDYKVLAYKHMCFPSSSTIAH
AELYTLSTSTWKEIDVGEEFQATGNLPYSTSYPSVNGIFSWFEIDNHVEKVIFSFDMKNE
VFMKTRLPDYNGIPSKRVHGCLASLKDSLAFIHDYPVGEFSKCFDVWVLGEYSVRESWMK
QLTIGPLLGVTAPLGFWKNGELLLQEEDETKRLVSYDPITKDMKDVQARGVAHILQVIPY
KESLVCFKEDEQESEQNRDDEIPFSVSECQEEDILHTIV
>Sgl55958 E3_adaptor/Cullin_RING/SCF/F-box 13.8 0.0
MSTFVTLPEDVITEILLRLPIKSLQRFKCVAKTWYARISDPCFMVKHFISSNNQEFFDCL
LIDQYHPTKLQVLSLLSSEPLQINMKHIQLSYANSIENTLCSTKILGPSNGIFCLFDPPD
CSISLWNPANQQLKTLPVSHIEPPPNAISYQNIVGFGFDNERNDYKVLVYKQMYFPSSSS
TPKIAHAELYTMSTNNWKEIDVGEEFQATNAPLSSPTSVNGMFSWFESDNTLVEMVVFSF
NMTTEVFMKTRLPNIPFKRDYERLASLKESLAYIHTHFVGGIGVMNDVWVLGEYGVQDSW
MKQLSIGPISNLRSVRGFWKNGELLIQTQRHKMVSYDPLTQKAKDVQLRGVFYISEVLPY
NKSPVCFKEDDEQESADHDHKTDVIPLCVTECDEEYLVQTIASYDD
>Sgl55968 E3_adaptor/Cullin_RING/DCX/DWD 129.9 17.4
MNYRFQNLLGAPYRGGNVVVSSNNKLISSVGNRISVTDLIKSETITLPCQSSANVSHIAV
SPDGNFILAVDENSRSQFINLNRRIVLHRITFKGKVSSLQFSPNGQFIAVAVGKLVQIWR
SPGFRKEFFPFELVRTFADFDDGVSCLNWSPDSGYLLAGSRDLTVRLFCLRKLDERKSNK
PFLFLGHRDVIVGAFFGVDKKTGKVLRVYSVSRDGGLFSWGLPEFDVKLGGLGDRDEEMV
DPPSPGTPDKVDEDGGVVGNDVNGNENGKKRKEFDGKAKDFGDESQLLLHKIEWKLLKKD
YFMQAPAKVTACDYHQGLDLVVVGLSSGVFGLYQMPDFVCIHLLSISREKITTAVFNGLG
NWLTFGCAKLGQLLVWEWKSESYILKQQGHYFDVNCLAYSPDSQLLATGADDNKIKVWNV
SSGFCFVTFSEHTNAVTALHFLANNHSLLSASLDGTVRAWDLFRYRNFRTFTTPSSRQFV
SLTADQSGEVICAGTLDSFEIFVWSMKTGRLLDVLSGHEGPVHGLMFSPTNAILASSSWD
KTVRLWDVFEGKGSVETFQHVHDVLTVVYRPDGKQLACSTLDGQINFWDPLDGSLMYSIE
GRRDIAGGRLMTDRRSAANSTSGKYFTSLCYSADGSYILAGGNSKFICMYDIAEQVLLRR
FQLTLNLSLDGVLDILNSKNMTEAGPLNLIDDNNSDTEEGIDKQVRGKLGLDLPGSMPNR
GRPVIRTKCLKISPTGRNFSAATTEGVLVYSVDESIIFDPTDLDIDVTPEAVDAALNEDQ
PSRALVLSLRLNEDSLIKKCILAVNPADIPAVVSSIPFRYLQRSMEALTELLEGCPFLEF
ILRWCQEICKVHGHSIQQNNRNLLPTLRSLQKAITSLHQDLAEMCSSNEYTLRYLCSTSV
RK
>Sgl56005 E3_adaptor/Cullin_RING/DCX/DWD 96.2 6.4
MSTFGSNTASTTSHNPNKSTEVVSPPGDSVSSLCFSPKANFLVATSWDNQVRCWEVTKNG
MNTATVPKASISHEQPVLCSAWKDDGTTVFSGGCDKQVKMWPLLSGGQPVTVAMHDAPVK
DVAWIPEMNLLATGSWDKTLKYWDTRQANPVHTQQLPDRCYGFAVSHPLMVVATADRNII
VFNLQNPQTEFKRITSPLKYQTRCVTTFPDKQGFLVGSIEGRVGVHHLDDAQQSKNFTFK
CHRDGNEIYSVNSINFHPVHHTFATAGSDGGLNFWDKDSKQRLKAMSRCNQPIPSGAFNN
DGSIYAYSVCYDWSKGAENHNPATAKSYILLHSTQESEVKPKPRTNTGRR
>Sgl56022 UBD/ZnF/ZnF_UBP 93.1 7.2
MEEATSAASASTHLTSDLPSNTIVSDESSTMISTQTLSFSSGNPRIEETSGVMHLYSNDL
TSSSSSSPLHLPVGRKPLVCVVGVPNHMTYADFCRFSGSFIQHMLEMRIVRNDEAEDTYI
ALIRFDDQDSTDGFYKHFNGQKFSSLEPEACHVLYIVDVQYTGSIERGQASLLSSTEQPT
CPVCLERLDQDTSGILTTICNHSFHCSCISKWTDSSCPVCRYCQQQPEKSTCIICETSEN
LWICVICGFVGCGRYKEGHAIIHWKETQHCYSLDLETRRVWDYAGDNYVHRLIQSKTDGK
LVELNVPCSHGMHGCGSCECSGDPGINEAVLSSKVEAIVNEYNDLLSTQLENQKLYFEAL
LQEVKEETEKEIAEAVDKAVSLKLQKLQAKLDRCIKEKKFLDDINENLSKNQEIWKAKIQ
EIEEREEKAIRLKDGKIRDLEEQLKDLMLDLEAGQAVEQQSLSDEVKSGSVLKIGGESST
SGASKSKNRKKR
>Sgl56036 E1 369 0.1
MTSQQQLDAIKGARVLMVGAGGIGCELLKTLALSGFQDIHIIDMDTIEVSNLNRQFLFRR
SHVGQSKAKVARDAVLKFRPHIQITAHHANVKSSDFNVDFFKKFNVVMNGLDNLDARRHV
NRICLAAGVPLVESGTTGFLGQVAVHVKDRTECYECYPKPAPKTYPVCTITSTPSKFVHC
IVWAKDLLFTKLFGDKNQENDLNVRSSDGASSSEHIDDVFEHRNGEDIECYGKRIYDHVF
GYNIEQALSNEETWKNRAKPKPLYSRDVLSDKQQNGNRDKTLSSDLASASVSAMATLGLK
NPQDVWNLTENSKVFLETLNLFYSKRSKEIGSLPFDKDDQLAVEFVTAAANIRAASFGIP
LHSLFEAKGIAGNIVHAVATTNAIVAGLIVIEAIKLLSKDDKNLRMTYCNEHPKRKMLLM
PVEPFEPNKACFVCSETPLVLEVNTLRTKLRDFIEKIVRAKLGMNLPMVTLGNSLLYEVG
DDLDDAMIRIYEANLEKVLSELPSPVVSGTVLVVEDLRQELSCKINITQREDFDEEKEPD
GMVLIGWSQAPTDTEKIASVENGESRSGTLVAKPLEIAQVDEAEGNLASKKRKSSEVSNS
SGSHPSSGNDLKNKNKEVIFEDDGDDLIVLDHLSSETAKKKRLV
>Sgl56043 E3_activity/RING/RING 23.1 1.2
MGAACCVASRDRTIQHGSSGEFLHRNFRHSPTWSFRWDNRVGVAGEEPSLGWLSDAASRN
DLMDVKSATDVSAQVSDGGSSLDSYRMGALRKSPVDHELTKSIKTSASGQSVARNASTEV
KQYTESPQPSDSASVKLSPLTHTSSLHMSPISAQSFPPPPSPTPSSWTRGSPAHLQAHQA
SDSHSSGRNSPINSVSEEGQVPFGNSAASNLSTRGSYGRSSDGWSAHGFSEIMSGSQRER
WSFDSDSGSLARDKLSRTSGHNSQSVSVDLQTCGICSKLLAENSAWSSQKIIAGNEQSIV
AVLICGHVYHAECLETITPEINKYDPACPVCTFGEKQTLKLTAKMLKAEKDLKAKNSKKS
RNQVVDTNTSFDFDYWKKSATVYEGKSPKLGNSSSLKISGAKPFLKRHFSFGSRGNKSAS
ESPSIRKKGLFWAKSSRE
>Sgl56089 E3_adaptor/Cullin_RING/DCX/DWD 131.2 31.6
MAAIAATAEEKKEKLSVTELKERHAAAIEQVNSLREQLKQRRRILLDTDVANFAAAQGKT
AVSFGQTDLVCCRTLQGHTGKVYSLDWTPEKNRIVSASQDGRLIVWNALTSQKTHAIKLP
CAWVMTCAFSPTGQSVACGGLDSVCSIFNLNSPTDKDGNLPVSKTLSGHKGYVSCCQYIP
DEDTHLITSSGDQTCILWDTTTGLRTSVFGGEFQSGHTSDVLSLSISKANSKTFVSGSCD
STARLWDTRVASRAVRTFYGHEGDVNAVQFFPDGHRFGTGSDDGTCRLFDIRTGHQLQVY
YQPHGDDDVPQVKTIAFSVSGRLLFAGYSNGACYVWDTLLAKMVLDIKSLQNSHTGRISC
LGLSADGSALCTGSWDTNLKIWAFGGHRRVI
>Sgl56111 E3_adaptor/Cullin_RING/DCX/DWD 118.2 7.8
MGEDEEMPMTEEQLKEEFEVWKKNTPILYDLVLFNPLEWPSLTVQWLPSSPVINSDSSLA
VHQLILGTHTSDHSPNFLMVADVHLPLKNTPCSSIPKVEIVKKFQVDGEVNRAVCMPQKQ
NLVAAKTSGLEVYVFDITKEPSSGVCDPEVRLRGHEKEGYGLSWNPLKEGYLLSGSYDCR
ICLWDVSSMPQSKVLDSMSVFQAHESIVEHVAWHTKNESMFGSVGDDGKLMIWDLRSDKP
QHSVEAHEKEVNYLSFNSFNEWIVATASSDTTIGLFDLRKLTTPLHSLSSHTEEVFQVEW
DPNHETVLASSSDDRRLMVWDLNRVGDEQLEGEAQDGPPELLFSHGGHKAKISDFSWNKN
EPWMISSVADDNTVQVWQMAESICCDEEEIPAE
>Sgl56116 UBD/UBC-like/UBD_UBC 236.9 0.0
MASRRILKELKELERDPPSSCSAGPVAEDMFHWQATIYGPHESPYAGGVFLVNIHFPPDY
PFKPPKVAFKTKVFHPNINSNGSICLDILKEQWSPALTISKVLLSICSLLTDPNPDDPLV
PEFAHLYKTDRNAYESMARSWTQKYAMV
>Sgl56123 E3_activity/HECT 347.1 0.0
METRSRKRAEASSSAPSSSSAGPTTRAAKRTRFSSANTATATPTTRSRSRTNISLSSATA
MDESSSRGGRRGKNHHGSDKDNDKGKEKEHEVEKERERENERGLGLNIDDDDDDDNDNDD
SEGGGGVGLLHQNLTSASSALQGLLRKLGAGLDDLLPSSAMGSASSSSHQNGRLKKILAG
LRADGEDGKQVEALTQLCELLSIGTEDSLSTFSVDSFVPVLVGLLNHESNPDIMLLAARA
ITHLVDVLPSSCAAVVHYGAVNCFCARLLTIEYMDLAEQSLQALKKISQEHPTACLRAGA
LMAVLSYLDFFSTGVQRVALATAANMCKKLPSDAADFVMEAVPHLTNLLQYHDAKVLEHA
SVCLTRIVEAFASFPDKLDELCNHGLVTQAASLISTSNSGGGQASLSTSTYTGLVRLLAT
CASGSTVGAKTLLLLGISGILKDILAGSGLVGNMSVSPALSRPPEQIFEIVNLANELLPP
LPQGTISLPTSSNLFVRGPLFKKSPMSSSSKPDEINGNVQDVSAREKLLNEQPELLQQFG
MDLLPVLIQIHGSSVNGPVRHKCLSVIGKLMFFSNSDMISKLNNSTNISSFLAGVLAWKD
PQVLVPALQIAEILMEKLPETFSKMFVREGVVHAVDSLITAPSTHAATTEKDTESTPGSS
ARARRLRRRSGNQHQDTNSVEESKNTVSVTVGSPPTSVELPTVNSNLRTTVSGCAKSFKD
KYFPSDPGAVDVGVSDDLLHLKNLCAKLNAGVEEQKLKVKGKSKTAGAYIADFSAGKEES
LVGIVSEMLEELSKGDGVSTFEFIGSGVVATLLNYFSCGYFNKEKISEANLPKLRQQALK
RYKLFISVALLTGVDGGDLTPMTVLVQKLQNALSSLERFPVVLSHSARSSGGSARLSSGL
SALSQPFKLRLCRAPGEKALRDYSNTVVLIDPLASLAAVEDFLWPRVQRSESGQKPSTSV
GNSESGPSPTGAGASSPSAFTPATSTRRQSARSRSGLNIGDTSRKESLQDKTNSASKGKG
KAILKPAAEESKGPQTRNAARRRAASDKDAQLKSPTGESSSEDEDLEMSPVDIDDALVIE
DDDDISDDDEDDHDDVLRDDTLPTCMAEKVHDVKLSDSAEDSAAAPATSDSQNNPASGSS
SRAATVRGSDSTDFRSGSSFGSRGAMSFAAAAMAGLASNGRGIRGGRDRHGRPLGGSSDP
PRLVFSAGGKQLNPNLTIYQAIQRQLVTDEEEDERYNGNDPVASDGSRLWSDIYTITYQK
ADSQVEKSHGTVSSASPSKSTKSGSASSSNVDASSHRSPLDSILQGELPCDMEKNNPTYN
ILSLLRVLEGLNQLAPRLRVQTASDKFSEGMILSLNELSATGSRVPSSEFVNSKLTPKLA
RQIQDALALCSGSLPSWCYQLTKACPFLFPFETRRQFFYSTAFGLSRALYRLQQQQGDGH
GSNEREVRVGRLQRQKVRVSRNRILDSAAKVMEMYSSQKAVLEVEYFGEVGTGLGPTLEF
YTLLSHDLQKVDLGMWRSNNSFDKSSMEIDSDEQTKDGKSEDASRLSSRANTNIVQSPLG
LFPRPWSPNADSSEGGQFSKVIEHFRLLGRVMAKALQDGRLLDLPLSTAFYKHVLGQELD
LHDILSFDPEVGKTLRELQALVCRKQYLESIGGDHPDVIAELCFRGTPIEDLCLDFTLPG
YPDYVLKPGDENVNINNLEEYISLVVDATVKSGIIKQMEAFRAGFNQVFDVTSLQIFSPD
EIDCLLCGRRELWKPDALVDHIKFDHGYTAKSPAITNLLEIMGEFTPEQQRAFCQFVTGA
PRLPPGGLAVLNPKLTIVRKHSSSATAAANGTGPSESADDDLPSVMTCANYLKLPPYSTK
EIMYKKLLYAINEGQGSFDLS
>Sgl56148 E3_adaptor/Cullin_RING/DCX/DWD 129.4 11.8
MLTKFETKSNRVKGLSFHSKRPWILASLHSGVIQLWDYRMGTLIDRFDEHDGPVRGVHFH
KSQPLFVSGGDDYKIKVWNYKLHRCLFTLLGHLDYIRTVQFHHENPWIVSASDDQTIRIW
NWQSRTCISVLTGHNHYVMCATFHPKEDLVVSASLDQTVRVWDIGALRKKSASPADDILR
LSQMNTDLFGGVDAVVKYVLEGHDRGVNWAAFHPTLPLIVSGADDRQVKLWRMNDTKAWE
VDTLRGHMNNVSCVMFHAKQDIIVSNSEDKSIRVWDVTKRTGIQTFRREQDRFWILAAHP
EMNLLAAGHDSGMIVFKLERERPAYSVSGDSMFYAKDRFLRFFEFSTQRDTQVIPIRRPG
SASLNQGPRTLSYSPTENAVLVCSDVDGGSYELYVVPKEQFGRGDMAQEAKRGVGGSAVF
IARNRFAVLDKTNNQVLSKNLKNETVKKSPLPIATDAIFYAGTGNLLCRAEDKVVIFDLQ
QRIILGDLQTPFVKYVIWSNDMQSVALLSKHAIVIANKNLVHQCTLHETIRVKSGAWDDN
GVFIYTTLNHIKYCLPNGDSGIIKTLDVPIYITKVFGNTIFCLDRDGKNKSIVIDATEYI
FKLSLLKKKYDSVMKMIRSSQLVGQAMIAYLQQKGFPEVALHFVKDERTRFNLALESGNI
QIAVASAKEIDEKDHWYRLGLEALRQGNAGIVEYAYQRTKNFDRLSFLYLITGNTEKLNK
MLKIAEVKNDVMGQFHNALYLGDVVERVKILENAGHLPLAYVTASVHGLHEVAERLASEL
GDDVPTLPEGKKPSLLIPPAPVMCAGDWPLLRVMKGIFQSDFDGADRVAAEDEEDIDTAW
GEELELYDAEKVENDDDDAVFNADGPVADDNEEPGGWDLEDLELPPEDDTPRASISARSA
NFVAPPSGTPVSQIWIQRSSLAAEHAAAGNFETAMRLLNRQLGITNFTPLKPMLLDLHTG
SHSFLRAFASAPVISLALERGWTDAASPNVRKQPALVFNFSQLEEKLKAGYKSTTQGKFS
DALRIFLGILHTIPLIVVESRREVDEVKELIIIVKEYVLGLKMETKRRELKDDPKRQQEL
AAYFTHCKLQMPHLRLALQNAMTVCYKAKNLSTAASFARRLLETNPGDQQKKLAEQVERA
AVKNMNDAIELDYDFRNPFVVCGATYVPIYRGQKDVSCPYCSARFVPSQEGQLCNVCELA
VNGADASGLLCSQTQIR
>Sgl56149 E3_adaptor/Cullin_RING/SCF/F-box 15.6 0.0
MDSNTASSPSYSSVDGELFDFLNSVELIDEHENDNENIDDIDDGMEVILSSWNNGSSVDD
ERDWGSSMPKELLTKIVEHVQHFEDFETMSQVCSSWRSAACDAIFGRERLNNNQTHTLPW
LLLPKNGADNYHSTCRLYSLSKREVRCVNLPAHKNDTYRFLSSHGWLLLVLDGHSGENVC
LFNPYSAYTIIPPPVNLSCPNCQGIPFFDSKFVLSANPSSTRDFIIFLALEQPLYINLLP
AMLVYWRSNYDRWIQIAEPPIPLGLALEPPQLTRFLDSMCRDITFYQGEFYGINFHGHVV
KFQTLQDKPHYEFITILETGYGELGNRQFEPDEKCFYYLVESRDKLLVIAQEAWVELDNL
NSYYVRRTRSFEVFELNVNNGTLNPVPSLGKRSIFVGSNSSFSVEVSHNNDHGFKPNCIY
NTDDRVTWAWTACGYGQKDACVYNLSNGMIDKFYHGPSLQPGRLTSFTWVESPHPSDKLE
PT
>Sgl56162 E3_adaptor/Cullin_RING/DCX/DWD 84.4 8.3
MATEAEELQQVENSQKRENEPKNALEVEQQERRENEELDPELFSCLLQPISADSDLDYVG
IRRFLLHRKAQSGDRRRIEWRCNGRGYVAYRNYINRPRNWENQLQSQSSSPNQSGRWITS
PGPLSLLYEADSLSSNRDLRGSSQARNSFSSSTSDYEHRSDRSRRTAEPAYSFVGMHCIF
DQCNVAVTVLKFGHLSSDLLAYGAADGSLTVCTVSDPPTVSKQLIGHSKDVTDFDFTANN
QYIASASLDKTVRVWDISKGVCIRVIYGVTSQWCIRFHPVNNNFLSVGNANKEINVYNFS
TGRLIHKQKLDDEVTAMDHDHTGQLLFCGDAQGCIYTVGMNSHTGALSRIHRNRNGSKRK
SPVTVVQYRTFSLLARGPVLLTCTQDGSLAFFSVALEVKGYLTLRCALKLTPRVHRIRAT
FCPLLSLEKGEYIVAGSEDSNVYFYDLTRPRHTCVNKLQGHSSCVIGITWNSGENLLASS
DAGGTVIVWKRAKIS
>Sgl56164 E3_activity/RING/PHD 37.9 7.4
MGKPRAPKRTLDSVTIKPLNKAIKSGDCVLMRPAEPSSPSYVARVERIESDARGTNVRVH
VRWYYRPEESMGGRRQFHGSKELFLSDHFDVQSADTIEGKCIVHSFKSYTKLDAVGNEDF
FCRFEYNSASGAFTPDRVAVYCKCEMPYNPDDLMVQCEGCSDWFHPACIEMTAEEAKRLD
HFFCQNCSSDDPKKLQNSHAASRLSDTKVDTKRRRR
>Sgl56166 E1 369.7 0.1
MTSQQQLDAIKGARVLMVGAGGIGCELLKTLALSGFQDIHIIDMDTIEVSNLNRQFLFRR
SHVGQSKAKVARDAVLKFRPHIQITAHHANVKSSDFNVDFFKKFNVVMNGLDNLDARRHV
NRICLAAGVPLVESGTTGFLGQVAVHVKDRTECYECYPKPAPKTYPVCTITSTPSKFVHC
IVWAKDLLFTKLFGDKNQENDLNVRSSDGASSSEHIDDVFEHRNGEDIECYGKRIYDHVF
GYNIEQALSNEETWKNRAKPKPLYSRDVLSDKQQNGNRDKTLSSDLASASVSAMATLGLK
NPQDVWNLTENSKIFLETLNLFYSKRSKEIGSLPFDKDDQLAVEFVTAAANIRAASFGIP
LHSLFEAKGIAGNIVHAVATTNAIVAGLIVIEAIKLLSKDDKNLRMTYCNEHPKRKMLLM
PVEPFEPNKACFVCSETPLVLEVNTLRTKLRDFIEKIVRAKLGMNLPMVTLGNSLLYEVG
DDLDDAMIRIYEANLEKVLSELPSPVVSGTVLVVEDLRQELSCKINITQREDFDEEKEPD
GMVLIGWSQAPADAEKIASVENGESTSGTLVAKPLEIAQVDEAEGNLASKKRKSSEVSNS
SGSHPSSGNDLKKQEQRGIQLLLAVADDSL
>Sgl56329 E3_activity/RING/RING 33.9 5.4
MAGRLRLLSTVNTSVSAGDAGLTSSQSDYVVILAALFCALICAIGLAIAARCVCLHHPLN
LFMTAPIPHTSAPPPGLNKKTLELLPTTKYICEAGTSNKQSDCSICLTEFADGDIMRILP
RCGHVFHVACVDTWLGSHSSCPSCRQLVLVVGQCHRCGGYSAQQGIHGTEVHMRETNTMC
RQDYVRAFLP
>Sgl56356 E3_adaptor/Cullin_RING/DCX/DWD 65.7 18.5
MSSLSRELVFLILQFLDEEKFKETVHKLEQESGFFFNMKYFEDEVHNGNWDEVEKYLSGF
TKVDDNRYSMKIFFEIRKQKYLEALDKHDRSKAVDILVKDLKVFASFNEELFKEITQLLT
LENFRENEQLSKYGDTKSARAIMLVELKKLIEANPLFRDKLQFPNLKNSRLRTLINQSLN
WQHQLCKNPRPNPDIKTLFVDHSCGQPNGARAPSPANNPLLGSLPKAGGFPPLGAHGPFQ
PTPAAVPAPLAGWMSNPATVSHPAVSGGPIGLGAPSIPAALKHPRTPPTNSSMDYPSGDS
DHAAKRTRPIGLSDEVNLPVNVLPVSFPGHGHNQAFNVPDDLPKTVVRTFTQGSSPMSMD
FHPVEPTLLLVGTNVGDIALWEVGSRERIVLRNFKVWDLTTCSMPLQASLVKDPAVSVNR
VIWNPDGTLFGVAYSRHIVQIYSYHGGEDIRQHLEIDAHVGGVNDIAFSTPNKQLCVITC
GDDKTIKVWDAASGTKQYTFEGHEAPVYSVCPHYKESIQFIFSTAVDGKIKAWLYDNLGS
RVDYDAPGRWCTTMAYSQDGTRLFSCGTSKDGESHIVEWNESEGAVKRTYQGFRKRSLGV
VQFDTTKNRYLAAGDDFSIKFWDMDNVQLLTSIDADGGLPASPRIRFNKHGALLAVSASD
NGIKILANSDGLRLLRTYEMSYDSSRASESLTKPLINPISANPISGNVNAAAAAAAAAAT
SSGLPDRSAPMVGMSGMNGDARSLGDVKSRILEETNDKSKIWKLSEISEPAQCRSLRLPE
HMRTAKISRLIYTNSGNAILALTSNAIHLLWKWQRNERNSSGKASANVPPQLWQPASGIL
MTNDVSDASSEEAVPCFALSKNDSYVMSASGGKISLFNMMTFKTMTVFMPPPPAATFLAF
HPQDNNIIAIGMDDSTIQIYNVRVDEVKSKLKGHSKRITGLAFSHSLNVLVSSGADAQIC
VWSSDNWEKQRSKFLQLPAGRAPTAQSDTRVQFHQDQTHFLVVHETQLAIFETKQLECVK
QWVPRESSAPISHAAFSCDSQLIYASFLDATVCVFSAANLRLRCRINPSAYLPANVSSSN
VHPLVIAAHPQEANQFAVGLSDGGVHVFEPLESEGKWGVPPPMENGSAGSVPTTPSVGPS
GSDQQQR
>Sgl56387 E3_adaptor/Cullin_RING/DCX/DWD 32.8 14.0
MTTPSEVNRQTLISVLACLKNENYKETVHQLERESGIFFDMEYFEELVINGDLDEAEKYL
SGFTSIDDNPYSSTIFFQIRQQKYVEALLRIEKKKAIDILTNELKFIIEHNTKIFEDLMM
LSKLEDIREVLKLIGYVDIKTARTNLFGFLKKSIHQNVAFQDKLHFPKSSIRLKELLSQS
MQDDRRSMPSYICGQPHDQSAPFPLSHLPRFIEAASSSIQLPITTIANSAVGGQVYTPGP
RLLFPTKAAADDLPEKLVAILSEGSSVSCMAFHPLQHNLIFVGTCTGDVSIWDVDSKQRL
VYRKFMAWHLLPKSLQSASQADDTVSVSCVSWSQDGAHIGVGYSKRVSQIYLNSGGTELN
NNLKIDAHDGCVRDIAFSKLPHRVIVVTCGDDNTVKVWHCAPNPNIPEKVLKGHTAAVHS
VCLDYIIEENGGLSESIISTDVDGRIIQWLNAELNTSYLSPGLSTMRMRFSANGSRLFSC
GTNKGGQSYLVEWEYCKGLKGDRPKGEYQGLGKSVSVVSFDIALSKYLAVGDESVIKFWH
MDHSNILELLMWVVCRHLHAFGLTKKEHCWLYQLLIMQFKYLPIQNDCSTI
>Sgl56388 E3_adaptor/Cullin_RING/DCX/DWD 39.6 10.5
MAMAEHEARILYNVRNKPQIRELPKFVDVNICLGGEFKVHNGVNEYCGGTSYTKYCAWLK
DLDVSYLRAEVESAMSIVYNGRVNSNFCIWYKVRGVDLKYVNKVVEGTDDIVALIDGRDW
YERVTIYVEEFKDVGKKADLKMKGKVSPRPKVKQEKAVAQPKPLRIGNSPTRRSPRLECW
PDVIVLPPNHPDIPKSPSQPKATKLKPTTKSKNTSSVKVKAHKVSPKPAPLPKPAPPQDI
PEQRTKTPPKTLPQEAKNTTVTPSPLKKSTPRRKQVARKHGNGKALKLKGKEKKAENTED
HVGGEAGWSSDSELSDLDVDFVPEEEDFADKEGVDDFVNFTPRDVTKAVVEAFRNYKDSG
NSKKKNEGDATVDGVEEKSYNSDELESLHGSDEEVDSYPTFNPRTDFSKKLSLFATGMPQ
ISARPRLPLCNRLERESGLFFNMEYFEELVINGDLDEAEKYLSGFTSIDDNRHSTKIFFE
IRKQKFLEALDRHDEEEAKNILRNELKFVIEHDEKLFEDMTKLLILTDDRIKKLGSVDAD
RTNLVGSLKAFIHENIVFRDKLLFPRTSIGRLSELLQQSMYWQHLRCTDYTNTPFSSLEL
ETLFTDHTCDQSHDHSLSSNFPVVNPVAEGLMPRPVGQRVTIPPRPGGIDYCMSFIPEIA
IERPLLLSPAIVTMPPEEGLSSRDAAASSSRIQQPITAITNSAVGGEAAADDLPKIVVAY
LSEGSSVSSMAFHPLQHVLLLVGTNMGDVSIWDVGYKKRLVASKSKASQTDDNDSINCVS
WSLDGALIGVAYSKGILCIYLYRGGAELKDFLQIDAHFGEVRDLAFSKLTSNLVLTCGDD
KTVKIWDCTTGTGLVLEGHEAAVHSLCLLYKKDDLWIQSESIVSTAVDGRIIAWMNSNPN
NSYLAPGRSIMRMRSSADELRLFSCGTAKDGQSYLVEWEDHKSGCLKREYWGLGKSASVV
EFDTTRNKYLAVGDESVIKFWHMDHSDLLETVDVGGLPESPCIRFNEEGTLLAVSTIDNA
IKVLANADGMDLVRFKETLGLRL
>Sgl56421 E3_activity/RING/RING 31.1 10.1
MGLGGDQSSSVSVSVSSSSCSCSSSSDSSGPIRVLLYFHKAFRGELELLLRLASDSDQTY
THRAAQLDKRLHFFRTVFTYHCAAEDEVIFMALDARVKNIATTYSLEHHMIESIFGSIFS
CLNSIMNKEEHEQDDHPFQQLTLHITTLQASISQHMTKEEQQVFPLLMTHFSDKEQGFLL
WQFVCSVPVVLMEDLFLWISSFLPPQQHLDLKHTITTILPHHTLLQQVVISWIDNTTQPH
CLNYQLDFFKHISTPSFSFSFPIIDQPHFHSDTPFHALFLWHTALRSDFKQILDNLSKIG
SNNFSTLPSLLVRINFLTDVLIFYSGALETIFYPLLQGASIFQTLPSYKAFPFKYEIEGF
QKIIFDVTQVNFANPTFFKMLCRKMEDLMLATTSHLSFQETKVFPLIINNYDHETQQKLL
FRSLCMLPLGLLKCVATWFSSHLPRDKLNCILLGVKHSSFLARPFASLLHQWIRIGYSGK
FTMEDLQEMFNSRLSYLFKQFREGKDLSNNLEHAMTKHTSLDSSSFFSHSLSRCFQQTEK
HGTLYSSGINLLVFSSRTSNQVHTIFGSPVEAVSANHREPRPMDHIYYFHKAIKKDLESL
VLDSTKLSKNLDLFVDFNRHFRLVRSLYELHSETEDQVAFPALEAKQKVQNVTKSYSIDH
KLEDGCFSRVAGILDQMSELYGTLSGSGVDEVGPASLKYHHLCVKLQESCKLLEKILNDH
IHREEIELWPLFRENFSTEEQEKIVGYMLGRTRAEILQKMIVWLMASLTSEEQQAMMDCW
RKVTKCTKFDEWLGDWWEGMESNVFSEVEKPDFSSSSTMGSLNTIVKHFSTGVSHNRGKN
FKVGRMKFPDDEARTINMVKTMEGLGKDNKKQKSFEYKMLLGEKEKHKKEGTLTDSVSEL
EAAIRKVSQDSSLDLQAKTRIMQDLMTSHCVVQSLPDSNRVITSESGKLPGQFPSYRDTE
GSILGCKHYQQNCKLVAACCSQIFTCRRCHDEVSDHLMDRKSTTQMMCMLCLEIQPIGPT
CLTPSCNKYSMARYYCKICRLFDDNREIYHCPYCNLCRLGKGLGIDYFHCMKCNACMSRS
LSSTHICREKCIEDKCPICHEDMFTSSDPVKALACGHLMHSSCFEEYTCMRYTCPVCSKS
LGDMQVLFGMLDALLAEEKIPEEHIGQTQAILCNDCEKKGIAPFHRLYHKCPFCGSYNTR
LL
>Sgl56431 DUB/USP 51 0.1
MMNEEDGGENGGEMNQEDGGENGDTFQSGLKQSMVQNSSVAQQRSQHVDALEFSTGERIR
LNGSGMDTFGAGLLNDIGEYNCFLNVIIQSLWHLRKFRVEFLKRSPTEHAHVGDPCVVCS
LHNILTALSLASGDSSSEPVAPATLRIALSNLYPESNFFQQGQMNDASEVLAVIFECLHL
SFTSVSGGSDCESVESNSLGSWDCSSPSCIAHTLFGMDIFERMNCYNCGLESRHLKYTSF
FHNINASALRTMKVMCAETSFDELLNLVEMNHQLACDLEVGGCGKLNHIHHILSNPPHIF
TTVLGWQNTCESVHDITATLAALATEIDISMLYRGLDPKNVHRLVSMKSKMAIYVKDKVT
GGASEFSMGAIEDKDQETGNQPLNGESESDDNVNLPILQLIPLQVNLENTP
>Sgl56432 DUB/USP 79.3 0.3
MNNTSQRKPSSPPLSQSMELELADSSMIKQECEKALNALRRGNHNKALRLMKESSNKFEN
SALFHRVHGTIAVKVAGIIDDPNAKHRHFRNAVESARRAALLSPSSIEFAHFYANLMFDT
ANDGKDYEEVVSECERALAIENPIDPLKDNLNNQQLEEKSAEVRIAQLQGELRGLIQKSN
IASISTWMKNLGGPPGEEKFRLIPLRRLSEDPLDSRYFSTTNSNARRPNEIKKATKTPEE
RRKEIEVRVAAARLLQQKSEQGQIAEEGRNGTGTHSATLVSGSGASKAAERRRNGSSRRI
ISFCERKDQVRSFWNSMSSEMKKGLLRVSVSDLMAHFSGLSNKDGGQAFEVLSEALEFGK
MNKSWKFWVCCHCGVMFSNADAHVQHVVQEHMGNLLSKVQSAVPHSVDNEWVEMFVSCPW
KPLDLTASVRMFEDLPKHEGSQYPGQENHTEKIGEFWIESLCSEEWGRFPKKKILSDGFN
GSFSEGEGGGNDSKFECKTYDSKKDSKLYSLPKNWPLLDDIEREKLLEKINSLFQMLIRH
KCLAITHLQKEVSHACGLGRYPGKVTQDDAVNHSLGSDCHERIVLNEDASSLLLDESLLN
SDGMSSDMGSKYSLSTSEKGVQYVSDSFLSWIYAGFSSDEQLATWCKLREERSQQGMELL
QMLEKEFCHLQSICDRKFELLGYEEALQGLEDLCLEESKKREHITEFAHCSYDSILRKRR
DELAEGENEDLFSSNRLELEAISSVLKEAENLNINQFGYEETYGGVNSHLCDLEAGEDDW
KSKDYLHQVDTCIEIAIQRQKEQMSVELSKIDARILRNVGSMQQLELKLEPASALDYRSI
LLPFMKSFMRARLEDLVEKDATEKSDAAREAFLAELALDSKKGSGIGNDNSRQMQDKMKD
RKKNKDAKRNKYLKAGSFNEHPEPSEQFSLAATSGCDYVHTDSVASTSRDDLKALEEEFQ
RKNELEAEERKLEETLEYQRQLENEAKQKLLVEQHQRKAVATSHGVEKYLHDVPLDPNFL
VAVQCEREQLVSKFCVEDLDGVNRNVVDGGVCADIADGVLDREIFSGTDSSEHRTFTKGK
RRSSTKLLEGRLQASHGKEIGNSCADMLQKDQVWNRDSGRSCSGNSDAGSKTLRQLQAEE
DEEERFQADLKKAVRQSLDTFQSGLKQSMVQNSSVAQQRSQLVDALEFSTGERIRLNGSG
MDTFGAGLLNDIGEYNCFLNVIIQSLWHLRKFRVEFLKRSPTEHAHVGDPCVVCSLHNIL
TALSVASGDSSSEPVAPATLRIALSNLYPESNFFQQGQMNDASEVLAVIFECLHLSFTSV
SGGSDCESVESNSLGSWDCSSPSCIAHTLFGMDIFERMNCYNCGLESRHLKYTSFFHNIN
ASALRTMKVMCAETSFDELLNLVEMNHQLACDLEVGGCGKLNHIHHILSNPPHIFTTVLG
WQNTCESVHDITATLAALATEIDISMLYRGLDPKNVHRLVSMVCYYGQHYHCFAYSLDHE
RWIMYDDKTVKVIGTWEEVVCMCERGHLQPQVLFYEAAN
>Sgl56447 E3_adaptor/Cullin_RING/SCF/F-box 12.4 0.0
MAGAAIPLDILHNAILPRLPAKSLLRFKCVSKQWLALISTHQFIKLHLSYAITNHLLILT
ANHNCFYSFNLDFPSDPALKLPTFGIDSVVVGTCNGLLCIQSFRPYRLSLLNPSTRTYRE
IPSLLPPRRCSALNFGFGYDSTNDDYKLVRIADRYPSLGFLTHQLDRIVHVYSLSTNSWE
FIELTSPHSSMGVRENGALLNNILLHWKFWCYQQGKYRIRCFHLCEKQWTHDVPLPEFLD
MNSSSQSNTSTKDALLDFGVLDGCLYLSTKNQQQSAIDIWLMNDYGVKESWTKLCQISDS
RVFRSLRVSPIAYTSLKHQILLRTVDKTEHKILWYDIKGESAETFEINGVADCIWIVASK
DSLASVPGGFQIGTNKEKDETELLLVDALM
>Sgl56564 E3_activity/RING/RING 38.4 4.0
MGDIDFTIYIPDWSSSESNNTLIGIAACLVVALCVYIVVKVKKLYQALFGSPAVSNGHDD
RDNNNNSTELKEVVVVVDEETVKEVSKNCSECAICLEKLGVEYEKYGREKGELVLKQCGH
KFHEPCMLTWFSHGNLTCPTCRRPCYAI
>Sgl56578 DUB/USP 353.5 0.1
MDDTFDLDDFPTVESSTFNFDNDDDILFSNTNLRRRRRRISSSSSLRYDRVFLVCYKWWN
DASKSECLGEEKGVFYAAASPSSDDDGGGSKEEECGTCTDDEIVLNFRREGDDEDDKDKG
EGFSDREYALISESMWFKALKWHSDYWTRIKDVGCSLTAENGNQDVFPIHLRLFVMRQTN
LLAVKISLMDNPVELYKRAYQIFNVQFDSVCIRDFSGQMTRFLEGDAALPPSDCLGQDPQ
EVLLELQVYGLPKHGKDTQSRKLEIAMQGRSNSGGPCSSYSTKMNGIAENHNSYLPFLSS
YSCTQGYRETGVLGLTGLLNLGNTCFMNSAIQCLAHTSKLVDFFLGDYKKEINYENPLGM
NGELALAFGDLLRKLWAPSGMPIAPRLFKSTLESFAPQFCGYNQHDSQELLAFLLDGLHE
DLNRVKNKPYVQVGNTEGCPDDDVAKEFWQCYLARNDSIIVDLFHGQFQSTLVCPICKKA
SVTFDPFMYLSLPLPSATMRTMTVTLLSSNNEHMLSSPLTVTVPKYGSCKDLIQALSMAS
TLRDDETLFVAEVYNHRILRSLEDPCDSLALIRDDDCLVAYQIPKETESSLLVIFMHQRS
ERHPGFRMTRPCWSLFGIPLVARISSLSRGSQIHEEYMKLLRPFLNTVENDNTEKSDKDL
AKIESRSSSNSDNSWSSDDEMGAQLHGASDFQFHFTDERGMVMGQRIKLGEPLDVSGETK
KINVLVNWSEKMWRLYEISHLNLLPEVFRSGFFASKPQESVSLYKCLEGFLKEEPLGPED
MWFCPSCKEHRQASKKLDLWRLPEILVVHLKRFSYSRFLNNKLDTYVDFPMDQLDLTGFL
ARESDQSANCYRLYAISNHYGSMGGGHYTALAYHGKRWYEFNDNVVESVDEEEIKTSAAY
VLFYRRISDT
>Sgl56597 E3_adaptor/Cullin_RING/SCF/F-box 14.8 0.7
MNSLHPSSSHFHVFSRFFLLTLLFVSLSFASLNQVNGKVQQQISSNSILVALLDSSYTEL
AELLEKALLLQSLEELVGRNNVTIFAPKNEALERDLNPEFKRFLLEPRNLKSLQTLILHH
VVPSRVDLTNIVKPTRKRAMSNHHLHLSSTNNKILVEDSVEVVDHNSIVRPDGLIHGVNK
ILIPQSILQNFNQRRELRSISAVLPTAAPTVDPRKTKRTPRSKMGPAGSPQAGPAVSIYE
ALAPGPSLAPAPAPGPGGPHHHFDGASQVQDFITTLVHYGGYNELADILVNLTSLATEMG
RLVSEGYVITVLAPNDEAMAKLTADQLAEPGAPEEIMYYHIIPEYQTEESMYGSVRRFGK
VRYETLRLPHKVMAEEADGSVRFGSGDGSAYLFDPDIYTDGRISVQGIDGVLFPTEEAKS
PSGVKKVVAKQRRGKLLEVACTLAAAFGQDSQFTSCSPRI
>Sgl56599 E3_activity/RING/RING 26.8 13.9
MVYNLGILHLCLSWANFGFFELSICPPFFLLRIPHFQKLSGMDLARESDDQVTDLAAIVE
GGVHGESDDACSICLEDFSQCDPSTITDCKHQFHLQCILEWCRRSANCPMCWQPVSLNDA
TSQDLLEDIERERTPKANRSRNPQAFYHPTVTNVDLHLPADGSEIDLEEHIFQHLAVAAS
RQSRHHVSRREGQQPGLSSREHHPFLIFSTATTPHDTSASTSQNPIRTESHSNVSTMNPS
TLDAQVSPSLSPSQMNEVSIRRVGSSVTSANRPRFLFETRSFASQSSQASHNIAEPSDMQ
SSESIRSRLNAWSMRYKESISRNTRGWKERLFARNSSMTSLSSEVRREVNSGICGLSRIM
ERLDSRMSSGSGHASESSQAGRRTETSDGI
>Sgl56639 E3_activity/RING/RING 21.4 10.0
MGCTVREKHIRTGRRSRLTKPTNTNTNTDVDHNHNHNHNHQSGINDRTSALAKSMLESGF
KPWTHNMGFNDSMQNSGSNPNNPNSSSTQNFGFDDSGWGYCTEEQLEEILLKQLEFLYNQ
AVSKLVSLGYDEEVVLKAVLRSGHCYGGMDVLTNIVHNSLTYLSSGCCGNDEEFEESELV
FMDLRQLEEYSLAGMVCLLQQVRPQLSRGDAMWCLLMSDLHVGRASTIEIPVAPSPSNFH
GGWGFGNEASSELPVNGLGGFFPYSEASFQREIDCAKRFNLSPSMKSLLKRNVAAFAAGF
RSKQQLQLQSQRCTTSAASGGSSKGTAPVVDVPSVPSAESKDSNQDIVNSLLSKFRDLNL
DENLDCVTEDQKDEIMLTLLHQVKDLEKQVTERKDWAHQKAMQAARKLSSDLTELKTLRA
EREETQRLKKGKQTLEDTTMKRLSEMENALRKASSQVDRANASVKRLEVENAEIRAEMEA
SKLSASESVTTCLEVAKREKKCLKRLLAWEKQKTKLQEEISAEKQKIADLRRQMLQILAS
QKEAEAKWKREMKEKELAMTQVEEERRSKEATESNNKRKLEALRLRVEIDFQRNKDDLQR
LEQELSRLKANAQPLEPHDSSDAFAKGSPEAATNQGESIERLLQDLDEPEKEGSERECLI
CMKEEVSVVFLPCAHQIMCASCGEDYGKQGRATCPCCRCPIEQRIRVFGASS
>Sgl56646 E3_adaptor/Cullin_RING/SCF/F-box 20 1.4
MDSNDENLVETKTLIEFDQSTSSSVVKEESHKLDLTNSTAMGGRISKSQENGSGVLEDEN
FHRNSANGGSDGGGGKDVMVGKKEASVADDVEVGKGVKEIKNDEKLDGIPIRSNGSGDGV
KEVCGKSGPVAEFQDERSSSDTKLNDDVSGSIAQRTRNRVVTGKKEDIDEDDVRMGNTSD
DDVDEEHGFSVGDFVWGKVKSHPWWPGRIYDPSDASEFALKYKHEGRLLVGYFGDRTFAW
CDPSQLKSFEENFEEMSKQSSLKTFVNAVQEAENEFGTLVKIQMTRSYARESQSSLPLVV
NAGVKEGVHIPETGIGFFTVAQFKPLAMLADIRRFAIFDSVANTLELTVLKSRLVAFNHA
KFGYSLPIHCEPIGIEDLTDNQGALLGPLFPGPDDGGMFVGPEDQPVGQNEPMTPVGMSH
STRKVKSIAELLERETKDKLKGHDLEKTKGETQSGKLVSTSRKKRWNVSDEDQSTVNEVK
GDDGSSKDEEQQPVRKSGRKKKMAVDENQSNEVGDVVVTRSSSRKNKQSSARSTSSEKKA
SASDGTEDGGKVKDQRKMETMPQVSVNSGSAVEEGYERISPREKKLSKYLCPPYTNILQR
QRSSCSQTSSEAGHVFSDVAKVGERMAKTPGKLTGSPPLVKCSAETFRKSSKVSGPMRKK
IDHPNQNTSKEDPSLEVKGPVKSINSVNSVLLDLRSAALDPLYSRRGQSFDSINGFISSY
RSSNYIDGSNYASYKKALADVRKRQRKRKRNVSDNEHLLGQKLLDAVDQQTPKSEPLEAK
STRKRKQKSESKAGREVGPSPSATLVITFPASFPLPTQKDIINMCSKMGGVDKSKTEVVP
ESSTVKIVFVQSSAAEAAMDSMQKSMPFGSVGVSYNIEHLATGSSDRKQLKVNVQNKKKM
KSSETSEATVANSLGKQLSVSPAPAPAPAPAPAPAPESDPLAIVFIKQKLEAMTSMLSQA
DGKMTQEIKANLENEAKELLKKVKKMTASPSE
>Sgl56692 DUB/USP 287.6 1.9
MDLEEETRKFKTLDPLQSIETEIPVVGEITVSKSMENDKPLSDVGVSDRIPGDSSGTQSN
VISSEEVNPILEITEIENQSSDFVQFNETLIGSSSIDESQCSKPLVELENGKKFDDIESS
KAETLDESVKEGDKKLEDSQIKKIIDDSVDEEGEDEELTKTLTELSAVAIEGDEIGKFNC
TDLLNDLENRNGFGDNSESGIGEEELSLVPGPWSEGHRNQCDCAHCLEAEQEEWSWRNNG
LGWPSSSSRMFQPKRHCRRRGFNFRREKEAEMYDYMGGYNARLNCLNIGYYEPEPCPVGA
GLANLGNTCFLNAIMQCFTHTVPLVEGLLSLKHKASSHGADEFCVLCAVCDQIEYSLVNS
GRVISPSNLVDNLSHISSYFRRYQQEDAHEFLQCLLDKLDYNWSKYETSDNDSLWSDDTL
VKQIFGGRLVSQIRCCSCGHHSVTYEPLIDLSLEIEDTDSIEGALKSFTKVESIEVTENF
LCDNCKEKVKVEKQLILDQAPSVVGLHLKRFKSDGIYVEKIDKKVEFPLELDLGPYTKGS
NDGHEDLKYELFGVVVHVGFSSTSGHYFCYIRTSPEKWYRFDDSKVTMVEEETVLDQHAY
ILFYVRKGTPWFDSLIENWKAECHKKILSTSPKSVLVDTDLQSSSFPARTSFLGGDGINT
GDSGFEVQNKPGVGIGLHSCEAAEMRDATWDASVAPTTELEQDEVEVKAGLDAWDAAGAN
QAYVSSSSVPKRNSLEDKGDGVKEIDANEDQNCKEIGKIEQISCGGTCSPSLVKNTFDGE
PQNEASISPSTPPRALSPDIYSDTEPTGEAYCIPTSHLKIKDKPSSAKKSVNTLKQDMKR
KEAAKYIRRSMPGGRGHMFMAAMSGSKSDSIMSKKRRKHASLLHGRQSPKKRVKVSPKRV
LRPVTA
>Sgl56703 E3_activity/RING/RING 29.8 7.7
MNTKDCSLKLCSTFCPQWCDGIFLPPSPPPPPPFTFPDDKSETSPTFSPLVIAIIGILAS
AFLLVSYYAIITKYCGKSNSSSRRSREIRRSNNEELFEDGNDDGGNTTNNTQQQHHEAWL
INTPGLDEALINKITLVSFKKGDGLIGSSDCSVCLGEFHEDDTLRLLPKCSHAFHVACID
TWLRSHLNCPLCRANIISTYSQPPPSNHNNPHIVVDNSNNNNNDNNNNNNVIQDHSTMVE
NQVAANEEISSSGEGRQQLEVIVEQGNGNIPKTTPFRALSDLGVRGHGGRDTMRRSISMD
HRHETRVSIPDVYVCSHGEDCIVQICRIDEQPLKITVGESSKVSVSSSSNTSAVLHCVKN
SVAMKRSFSGGKFLFSKHVKGKNAVNPL
>Sgl56706 E3_activity/RING/RING 30.4 13.3
MSSIESPPIPEPPYPQDPTPPVTLVLTILLLVMFFVGFFSIYFCRCFLENIVNSLNNRQT
PNGTPINPSSLTPPGLDNKIVSSFPTFSYSTVKDYRREKYGLECAICLCEFDDSDMLRLL
TTCCHVFHKDCIDLWFESHRSCPVCRRNLDALEIRQSSERIPNVIESTRNSIGNNIVVDP
EIADGNNNNNNNNSNSMDNDAIIVIKEDSYEEPIDEAASSSSKGNIQDLYSNEKFSRSHS
TGHSIIRNNPKEDDDKYTLRIPEHIRRHLALSWANLGEYSNNSTSKHECFGEISGTATQG
DTNKVLV
>Sgl56718 E3_activity/RING/RING 21.7 11.3
MGKSHQKKQNFSQRRQRTSENRKEKLLHDCNDHHLGDDTKKIQTCSSSNFQPSYQPKFKW
VSRNSGAHVENSGSGPKLEVGQSSSDNGPKPEVCQSSCEVGESSFDERESEVRERKCGDE
EEKVEEGFELNEEGGGVDDVVRRLEELQLGVEEVELSEEQINNNDQAQEDELLAMESIYG
DSVYVIEKRQGLRSFQIHIHIELPSAYTVSAKFNADTHDESTSSNSDEFLYNFKVQYLSP
IILTCLLPRSYPSHSPPSFIVSVQWLHESKISKLCSMLDMLWNEQPGLEILYQWVDWLHS
SALRYLGFEEELLLGPYSMRSISDRRALSGSISADVDIPSMKSYNEERQHENFLNGCHEC
CICFSEYAGTEFLRLPCHHFFCTKCMKTYADVHVKEGTVKKLQCPTTKCGGMIPPGLLKR
LLGEEDFERWESLMLQKTLDSMSDVAYCPRCETACLEDEEQHALCSKCFFSFCTLCRDRR
HVGIACMTPEMKLQFLQERQKIFRTIKDGQRHMELEKFNELLSLTEIRRDAKQCPSCKVA
ISKTGGCNKMVCSNCGQYFCYRCGKAISGYEHFNEKGCELFPQEMIQHWEQRMNNRQAIG
QIQANLYAANVQPCPNCRQVNAKVGNNNHIFCWACQNHFCYLCRKNVRRCSEHYGPRGCK
QHTVG
>Sgl56744 E3_activity/RING/RING 34.5 6.5
MRTVNNTSLSTSNAGPTPTTPDFSGQDESVGGFTYGLGVSIGILVLITTITLASFFCTRD
EANQSEGQHQNHHHQGGENDHTVITIEGIDEKTLNTYPKWLYSQLKLTKNNDNDNKKGST
VMSCCSICLADYKGNDVIRELPDCGHVFHLQCVDPWLKSHPTCPVCRTSPLPTPQSTPLA
QVGVAPLASTPNG
>Sgl56752 E3_activity/RING/U-box 105.8 0.8
MDFSEEIEIPSYFLCPISLQIMKDPVTVCTGITYDRESIEKWVFNNNNTICPVTKQPLNV
VENTTDIFLTPNHTLRRLIQSWCTLNASYGVERFPTPKAPVTKAQVQKLIDEAMTHLSPH
RVVKSLETIKSISTQSGANKRCLETTPGVPEFLARVIVLGEDEEDRLLYVNNTRVSDEAL
RILAHLQILDSEIVLRKMLNEKVGNKLVESLVRMMQRSNYESRAYAVGLLKQLVQVGDPT
HVVALKREHFVEVVSLVKDDISPKATRAALKVLALACPWGRNRIRIVESGAVPVLVGILV
ESNDKRIIETALAVLDYLSGCAEGRAEILGHGAGLAIISKKILRVSSFATEKGVKILSSI
CKFSGSPSVVQDMMQLGVVMKLCLVLQVDCEAKTKEKVREILKLHARAWRNSPCVPAHIF
GSLC
>Sgl56753 E3_activity/RING/U-box 100.9 3.4
MDFNEEIEVPSYFLCPISMDIMKDPVTVCTGITYDRESIEKWVFNNGNTSCPVTKQPLNI
VNENTTTTTMAADIFLTPNHTLRRLIQSWCTLNACYGVERFPTPKVPVSKAEVRKLIGEA
EAHSSSPQRLLKCLEMIKSISAQSSANKRCLETTPGVPEFLARVIVLGEEEDEEGRCGNK
NGSSMRMMGGSRVSDEALDILAHLRIPDNEIVLKKVLNENEGKLVESLVKVMQRSNCDSR
GYAVGLLKQLAQIGDPTHLAALKREQFVEIVKVVKDEVSPKATKAALRMLALVCPWGRNK
IRVVESGAVSVLIGLLVESNDKRIVEMVLAVLDHLSGCAEGRAEIVGHGAGLAIVSKKIL
RVSSFATQRGIKILYAVAKYSGSPSVVQEMLQLGVVMKLCLVLQMDCEDKIKEKAKEILK
LHARAWRNSPCAPAQIFGST
>Sgl56832 ULD/UBL/ATG8 161.2 0.2
MAKSSFKQEHDLDKRRAEAARIREKYPDRIPVIVEKAERSDIPNIDKKKYLVPADLTVGQ
FVYVIRKRIKLSAEKAIFIFVDNVLPPTGAIMSSLYEEKKDDDGFLYVTYSGENTFGYPS
ME
>Sgl56970 E1 578 0.0
MLPVKRPAGGEADNDEVVEVFAFNSTLKKPCLISIAAASSSSALTATANGNAQGSENGES
ENSTMGLGDGDSKKTNNNNPNDIDEDLHSRQLAVYGRETMRRLFASNVLVSGMQGLGAEI
AKNLILAGVKSVTLHDDGVVELWDLSSNFIFSEEDVGKNRAHVSVQKLQELNNAVAVSTL
TTELTKEKLSEFQAVVFTNISLDKAIEYDDYCRSHQPPIAFIKSEVCGLFGSVFCDFGPE
FTVVDVDGNDPQTGIIASISNDNPALITCVDDERLEFQDGDLVVFSEVCGMTELNDGKPR
KIKNARPYSFTLEEDTSGFNPYEKGGIVTQVKEPKVLSFKSLREALQDPGDFLLSDFSKF
DRPPLLHIAFQGLDKFISTLGRFPVAGSEEDVQKLISFVKEINDSTTDSKLDDIDQNLLR
HFAFGSKAVLSPMAAMFGGIVGQEVIKACSGKFHPLFQFFYFDSLESLPTEPLDPSDLKP
VNSRYDAQISVFGAKLQKKLEDAKVYVVGSGALGCEFLKNLALMGVSCGSQGKLTITDDD
VIEKSNLSRQFLFRDWNIGQSKSTVAAAAAAVMNPRLNIEALQNRASPETENVFDDTFWE
NLNVVINALDNVNARLYIDQRCVYFQKPLLESGTLGAKCNTQMVIPHLTENYGASRDPPE
KQAPMCTVHSFPHNIDHCLTWARSEFEGLLEKTPAEVNAFLNNPGEYASSMRKAGDAQAR
ETLERVIECIDKDRCDTFQDCITWARLKFEDYFSNRVKQLTFTFPEDAVTSTGAPFWSAP
KRFPRPLQFSTDDATHLNFVLAGAILRAETFGIPIPDQIKSPQALADAINKVIVPEFEPK
KDAKIVTDEKATSLSNASIDDAEVIEQSIARLESSRGRLSPSFRMNPVQFEKDDDTNYHM
DMIAGLANMRARNYGIPEVDKLKAKFIAGRIIPAIATATAMATGLVCLELYKAMDKGHKV
EDYRNTFANLALPLFSMAEPVPPKVIKHQDMNWTVWDRWILKDNPTLRQLLDWLQSKGLN
AYSVSYGSCLLYNSMFPRHKDRMDRKMVNLAKEVAKAELPAKRKHFDVVVACEDEEDNDV
DIPQVSIYFE
>Sgl56974 E3_adaptor/Cullin_RING/BCR/BTB 27.2 0.0
MQNNILSTMRSLKLIDGCKGTQVYAINTSSTTTTTTTTNGGDNNNNNGGGVGGTISGTGE
KLLHQLQDHLRVNSVRSKTRTNSNLDAKILQTNLLQEAVLPFGLPSTDLVEPQVETCLKF
VDFVETLADIYRRIEGCPQFEKSKFYVEQCAIFRGLSDPKLFRRSLRLARQHAVDVHTKI
VLAAWLRFERREDELIGSSPLDCCGRNTECPKASLVSGYDPESAFDDCVCRRVGNDVILD
GNGDGDGDGDGEDGSVAEEDDSEGFTRIEDEECSTSEEDFDMSFVVGEEEVWCIRDNIAS
LSRPFETLLCGSFIESKREKINFTQNGISAEVVRALEFYSRTKSVDRFNPQLVLELLSLA
NRFCCDELKSACDVYLSSLVVDKERALMLMDYGLEEAASLLVAACLQVFLRDLPGSLHDQ
NVMKYFCSSDASNKLAFTGHYSFLLYYFFSQTAIEEDMKSNTTVMLLERLVDSATESWQK
QLAFHQLGCVFYERKEFKDAQNWFEAAAEAGHVYSLVGVARTKYKRGHKYTAYKLMNSLI
SDYNPTGWMFQERSLYCVGKEKLSDLEKATELDPTLSFPYKYRAIALLEDSKLGAAISEV
NKVIGFKVSPDCLELRAWFSIAFEDYEGALRDIRALLTLEPNYMMFHGKMPGEQLVELLR
AHVQQWSQADCWMQLYDRWSSVDDIGSLAVVHHMLANDPGKSLLRFRQSLLLLRLNCQKA
AMRSLRLARNCSTSDHERLVYEGWILYDTGHREEALARAEESISIQRSFEAFFLKAYALA
DSNLDEESSSYVIHLLEEALRCPSDGLRKGQALNNLGSVYVDCEKLDLAADCYMSALNIK
HTRAHQGLARVFHLKNQRKAAYDEMTKLIEKARNNASAYEKRSEYCDREMAKRDLTMATQ
LDPLRTYPYRYRAAVLMDDHKEEEAIAELSGAIFFKPDLQLLHLRAAFHDSMGDYAATLR
DCEAALCLDPTHVDTLKLYSEARERVVDQQQSSFEDVDRNDALES
>Sgl56976 ULD/UDP/UBQ/UBQ_Other 40.3 0.0
MNQSEEVDEKEWEMRPGGMLVQKREDGDEDDGGPMFKIKVSYGSSFYDFTLPCKFTFGEL
KKLLAQKTALEPEDQRLFFRGREKEDAETLLKAGLKDHSKLLLMERPASKEKKLEEARKK
EEISKACAAIAGVRAEVDKLSQRVSSLEASVISGTKVDEKEFIIATELLMVQLLKLDSIE
AEGEAKTQRKNEVHRVQGYVDALDALKAKNSNPFGDCGNTVSVSTNWETFDSGVGSLTPP
SVSSTKVTEDWERFE
>Sgl56980 E3_activity/RING/RING 31.7 9.0
MDFTNYYPNTNSSSSSSTPINNYIPPSSSYYTRIVSNNTSTRYTKNGNNNKNQGNKLNNN
NKNKAKTRLSTDPQSVAARLRRHKISDRFKILQSLIPGGAKLDIVSMLDQAIHYVKFLKA
QILLHETILDNNNNNIDSSIDINSDIDNNDINNNNYNGASASATTYYYYDDDHQCCYAPI
MCNGYCCDNNNNCHNNVSDEQQSFGGAEEGNMVTVSWNHGEAQQIHDLWGTNGQRLNHRA
PVHGSHAMVVEKPQQFNFNMDIDQDLQVNGIGKGVVFSLFIFFVIVFLALGFIYYLYTSK
HQSHSGTVQTTAHLSVQVHSTSSNSGLELGPVTCESVINNLPVVSYGLGPIKNSQNCKQE
VDCCICLASFEEEEKVKVVPNCFHAFHSECLDQWLVNRLSCPLCRGSVS
>Sgl57010 E3_adaptor/Cullin_RING/DCX/DWD 14.4 14.5
MFAKRLLQKAIHHHHQHQNQKDTQHETYKPNDLDPQILIHFGIPNTASILAVDPIQQLLA
IGTLDGRIKVIGGYNVEALLTSPKQIPYKNLEFMQNQGYVVGVLNDNDIQVWNLERRCIT
CSLQWESNITTFSVLSGSPFMFVGDEYGMVSVLKFGAEEEILVNMPYHMSPDYIHEKTGI
SLPNDQSVVGVLPQPSSFGNRLLIAYQYGLFILWDILESKVIVIKGDKDLLIKDHVSDSP
SELAADPLDNAHEHMNEKEISALCWASSVGSMFAVGYIDGDILLWNIPRGASIKRKNASV
SRDDVVKLQLSSAEKRLPVIYLCWGESSMSQSSCGGQLFVYGGCEIGSEEVITVVSLQWS
PGMEVLKGVRRVDFSLIGAFADMVSLSSLETAGKSLFDGLFVLTRPGNLKFYSTDCLSAL
ISQPERKSSVSGIEFPVIIPSSDPQMTAAILSLQPSDGNLSMWLSEMASVFSTLNPAEGK
KWPLTGGVRRKISSAEENSQNLIYIAGFQDGSVRIWNAADPIFPLVYTIEGQVHGIADVG
ANISVTKLDFCASTMNLAVGTYCGEVRVYCLNNDSGGIKLHWIKHAEHIVYDVPSQKGPQ
CRAVFTLMNSPVQSLQFSVSGAKLAVGFESSHVAVFDMIALSVLFSTDPVANSNSQVISV
NLNTFSDAQGSTTGPKHSESKNVELAGEELLFTLTRDAKVNVVNSKTGSPISSRSLQLKE
HTAISMYVLEGSCFSSASSTEHHEQSNKETKILDEAKQDISKRKDDMKETKLDSGVLVCC
ENTVRLYNTKSVIQGEDKPFCKVKLAKPCSWTSIFTEDDKGFGLILVYHSGELEIRSLPG
LEVLAESSLTSVLRWNMRLNMKLASSTDHGHVFLANGSELAFISLSTSEIEKRFLESLPL
LHDEVLAAAADAAISFSIKQKKQVPHAGIIGDIVKGFKKEKQNDANDSIPACNFTQIGEI
FSRPIVPESSMTAEKYEEEEEEELDIDDIEIDEPVMVASTSSHQAKGKTTKSERDKLFDG
APADLKPKTRTPEEIMAKYKGAEYAAAAAERAKNKLVERQEKLEKISQRTEDLRYEAENF
ASMANELVKTMEGKKKWWKI
>Sgl57018 E3_activity/RING/PHD 35.2 8.8
MSSSNPRTVEEIFKDFSARRSSIVRALTSDVDEFYGLCDPEKENLCLYGHPNESWEVNLP
AEEVPPELPEPALGINFARDGMNRRDWLSLVAVHSDCWLLSVAFYFGARLNRNERKRLFS
MINELPTVFEVVTEKKPVKDKPSVDSGSKSRGSTKRSNDGQVKSTPKLTADEGFEDDEDE
QGETLCGSCGGNYSADEFWICCDICERWFHGKCVKITPAKAENIKQYKCPSCSLKKAGRS
H
>Sgl57022 E3_activity/RING/RING 19.2 13.8
MAETSSVPPPSPPSPTDEGPSSSSTTSFGGQSRSSEVEERVDEPSEAAPQPPAMTYRVRS
PSRYTTTTDDHSADDNFSCAVVVLTFWFFVSMTLIMGIFGSDTLQVGPNSSILLRPNSLF
VESLKVETSDDTEAAPVLYGFYETPPLENTKLWSESVNATIQPGYHKEWIYYLNKGSQMN
VSYNVVGSSSLLLVVAKGVEGFAEWLEDPSYPDSTLSWNIIRGRGSLRQDITRSYDYYVG
IGNVNSMRVKVELNFSIRSSMHAITDSYYKCGLRNSGVCNLKIPFPGGTAALLTTPEPLE
ATGGNRMKVKLSYEPRWLTYFLGIGGMTSIMLGAFNLLNKIRRNMQDDTENQSVDMGSER
APLLSRKDDDLLSLGSSYDSASQDGDEPQEDLEEGCKRLCVICFDAPKDCFFIPCGHCAT
CFSCGIRIAEDAATCPICRRKMKKVRRIFTV
>Sgl57055 E3_adaptor/Cullin_RING/SCF/F-box 26.8 0.0
MSNLDEEDEFLAQFLESEVLSEGSDQDDDTKDMERPMKRMCTEDILRETNNHACDSDGDC
GAKVKSSSCSGSSTADVNAERRIETGILSKIPPELFQHILKFLSSEDLFSCSRVCKFLNN
VASEESLWHRLYCLRWGLLPPTKKLRDHAWKKLYIQRDERDMVLSMKNCQPEFKEYYLQM
YAAKRSQAPLRSQVNDDLIFVDKTVADQVSIWKRSRGLSDKVVTDHTCSGEVCSYFQIGN
VFICEKTGNVHVCDDTCKEVIVDPENMLLVCTISGRCYDRVVSQSDEEDEFDREQQQGAA
VDEPEVFIGKGRFARAYMMGYNCEDEKELEDALRYV
>Sgl57076 E3_activity/RING/RING 28.1 7.7
MGSGSSKTRRIGGSSASSASSTSSFSSSVSSSVGRRSKTRGVFSSSCLGSSSRTYGSDDD
DDDDDQVSDRHVEAIRTRLQRPRTESDEVKVDCYQASKIDEPNNLPCVSSNTELGEWDYA
NGVDNGIRADESSSQAFSGQSMNHSNRFLSRFSFVPGSVSFRLNRAASVGSSRAYPSSPT
SFAVSSNEGDRHVPGGFPNRLGISNESQHSSSLNSSCPTSATVRSHGNSSINLVGHLANS
TLSSSLQGNQAISAQDLEDNDSERIRPGVCLPSLGRHMEMEGLNRRIGDRRNGAREPAER
NVRFSRTLSVGRLRDRVLRRSSFSELTLSPLEQESAAASDGNSVNSLMPSPHLLSSLPNS
YHPSQSNDVENAHLREGRHHDLLEHRSNFLERRRRIRSQVRALQRLGSRFDNLSGHERYC
ILSGQHRTGRCSCRTGTRDSNSNNDGGARASISRIVMLAEALFEVLDEIHQQSVVLSSRP
SVSSIGSVPAPSEVVESLPVKTYTKSTKVQNEEVAQCYICLLEYEEGDDMRTLPCHHDFH
KKCIDKWLKEIHRVCPLCRGDICRSDSVPVEGGSC
>Sgl57164 E3_adaptor/Cullin_RING/DCX/DWD 91.8 18.6
MEEEDVFPPSSSSSSKPYLINHPSKIARPSLNLDKIEEGPTTPSRVIDRMINSNHFPSPS
RTILSDRFIPSRTSSNFSLFSLTSPNSSSSSSTSTPNSNSNSTPQSSKQPDGARDDSSSA
YTSLLRAALFGPDSGSFFPGTPDKGPQNRNIFRFKTETKRPLPSLMPFGPDDSLPGVSYS
PVKSPRKVPRSPYKVLDAPALQDDFYLNLVDWSSHNVLAVGLGNCVYLWNACSSKVTKLC
DLGDDDNVCSVGWAQRGTHLAVGTNNGKVQIWDASRCKRVRTMEGHRFRVGALAWSSSVL
ASGSRDKNIYLRDIRAQDDYVSKLTGHKSEVCGLKWSYDNRELASGGNDNRLFVWNQHST
QPILKYSEHTAAVKAIAWSPHLHGLLASGGGTADRCIRFWNTTTNSQLGCVDTGSQVCNL
VWSKNVNEIVSTHGYSQNQIVVWRYPSMSKLATLTGHTYRVLYLAISPDGQTIVTGAGDE
TLRFWNVFPSSKSQNTDGELGFLSLGRAQIR
>Sgl57191 ULD/UDP/UBQ/UBQ_Other 46.5 0.0
MMKKTNINNNNNNNNNNINVGKMQGHEWEMRPGGMLVQKRNLDSNKNTSIPFPFPSIKVL
VKFGSSFHEITINSHATFGELKKRLSEVTGLHPQDQKLIFKERERESNSFLNDSGVNNGS
RIVLVKNTVIIQDKTFTDSRRNLTMDRALKSVAEVTIEVDKLVSQVTSMETVIWKGGSVA
EKELLSLIELFMAQLIKLDGIVADGDVKLKRKTQVNRIQRYMDNLDGLKAQNAMAIRNGG
GGGGGGQVGLIVSQQQQGRPLIIQQQREQRKFSGMTSKWEKY
>Sgl57197 ULD/UDP/UFD/UBX 49.1 0.0
MATVNQEAIETFMSITGAPETVAIQRLQEFGGNLNEAVNAHFSEGDRNVMQEAPITGTGT
PNDLMDIDDPPVLEPRGPASLLSATRGMNPFSLLDPALRSSLHDTRNIFDTSPELMGRAP
IVTQPREVRQIPIEVKDDGDTLAAPSGHGPRIEDVTDIIDAEGPQIHGTVVAADENDDAI
SADIGATRSSSRPSAPQFDDASGYANDIEEEMIQAAIEASKRDAELQNNQGLDAVSLQQG
PPHRDDAEIAHAVSLSLKTAERESLKREGSLKAGASGSAANDPVEMEEPGKIDEPIRRQG
VSSSDKSSSSHDKIEAGGPSIQDEVDELDEHPLVRNRSRRRSAVSTRNPREVGESVVSPA
GNPLEPTVASQAHPNGNAFPTDEWGGISSEEHDEAVMLEAAMFGGIPESGYRVPFAPHQM
MHPGVDTSWRMPRPPSPGLVAQRAIREQQDDEYLAALEADREREMKAIEEEKAAREAALE
EQKRKEEESRKKFEEEQELERQLAAKEASLPEEPSLDSENSVTLLVRMPDGSRRGRRFHK
SDKLQSLFDFIDVGRAVKPGAYRLVRPYPRKAFSSEDSNLSLNELGLTSKQEALFLELI
>Sgl57214 E3_activity/RING/RING 31 13.1
MSSLDASPFISPPPSHPTTARAQGVSYATRMIQRASGLGRYLRAASVTVRETAAREIEGR
QTDWYYSHPIVVLDAIWNLAFVLAAFTVLFLTLSDSPRLPLRVWIVAYALQCLVHVFCVS
FEFRRRMRTSIAVADATHATEDNSEDSGTMIKQLETANTMFSFVWWILGFYWICVGGNGL
LIDSPLLYWLCIAFLILDLCFAFFCVILALAVAVAVCFCLPCIIAFLYVMQDLPQGASKE
DVGLLRKYTFLKCDSKEINGEIESSCGGIMKECGTDSPVERTLTAEDAECCICLGAYEDG
TEVRELPCNHHYHCSCVDKWLYINSTCPLCKYDVLKGTYDDGEV
>Sgl57235 E3_activity/RING/RING 31.8 3.9
MMEVQPSFSQFLQQNSGMEVVELARTAVNTLNKLANWGQYSNQPGVGPKEGDVLMDFLAK
IDGRLVRVARKRAKVSGRNFEEVFAETKFEFYFNEAKFMETEMLVDPREEVVKVARTVTE
ADKGEVCGVCQEEVEEGDVVVTTACMHTFHGLCLWTWLNGRKTCPLCRFTVLQ
>Sgl57283 E3_activity/RING/PHD 54.6 53.9
MGKGRPRAVERGGGLGQISAANGSMNINPAPVYYPTEEEFKDPLEYIYKIRGEAELFGIC
KIIPPKSWKPPFALDLDSFSFPTKTQAIHQLQARPASCDSKTFELEYNSFLESHCGGRKP
RRKVVFEGEELDLCKLFNAAKRFGGYDKVAKQKKWGEVFRFVRPSSKISECAKHVLAQLY
LEHLYDYEEYYNELNKGKSKGCKREMHSRDRKRDQISDSSSSKKRQKGDSGEAVKVSKDS
KPKKEERDQICEQCKSGLHGAVMLLCDRCNKGWHTYCLSPPLDAIPLGNWYCLECLNSDK
DNFGFVPGKSLSLEAFRKIADRTKKKWFGSASCSRMQFEKKFWEIVEGSLGEVEVMYGSD
LDTSVYGSGFPRSNDKRPESIDGEVWNEYCNSPWNLNNLPKLKGSMLRAVHHSIAGVMVP
WLYMGMLFSAFCWHFEDHCFYSMNYHHWGEPKCWYSVPGSEASAFEKVMRSCLPDLFDAQ
PDLLFQLVTMLNPSVLQENGVPVYSVLQEPGNFVITFPRSYHGGFNLGLNCAEAVNFAPA
DWLPHGGFGSELYKLYHKPAVLSHEELLCVAVKIGCDAKVAPYMNKELRRVFSKEKIWRE
RLWKKGLVRTSVMSSRKHPDYVGTEEDPTCIICQQYLYLSAVVCRCRSSTFVCLEHWERL
CECNPRKRRLLYRHSLGELGELLAMTENVTSCSNGNPRRNVLPRQNICSIDSDTLTKKVK
GKQMSFAQLAEEWLLNSCKILKLPFSSSAYASALKEVQQFLWAGHEMDPVRDVMRNLVQA
KDWAERVRNSLSAVESWSENGAKDVDKVHLEHINNLLKHDLLPCNEPGHLKLKEYANSAS
LLAQEINNLLSTSKFSVAELENLFNQTSSFPIYIRESETLARKISSLKVWLDSVKKCVTE
TSPAAIEIDFLRHLKEEMLELQLHVPENEKLLELIGQAELCQAQCNEMLKGSITLEKLEL
LIYEFGALVVNIPELKVLQQYHSDTISWLSRFNNVLVDINEREDQENVVEELRCLLKDGS
ELRVQVDELARVDVELSKACCREKALKVRRYKTEIGFVQQVLSEAAVLQIESEELFVSLS
QMVATAFSWEERVTKILAFESILDEFEDAIRSSEDIFVNLPSLPTVQDAVSAAYAWLESS
KPFLQASVPTTSDSNDALVFEDLKELVYQSKFLKVKLAEIGLIEAILKKCEEWRHRACSS
LKDVEELLNRKDIFSRLHCDVILEIEELRAMVVSVANAGQSLGFAFPEVSRLWNAASTLK
WCSKVLIFHFEPPSLQDVDNLIEEMKDLPIGEAVAFVLVSLVDAVSWLKKAAVFLSVSST
EEKRKCHLESAEDILVKSQDMLVSFPAINVQLEQAIKKHKLWQEEVQAFFSDNSSDRSWS
SLLHLKELGKGSFDCLELDMIMSEFETVGNWKRRGEELVGCSDGDATNLFSSLLKIKQSL
HRSLYIYEKSRCWKVRYFCIGCSSNSDDLEFVTCSTCKDCYHLRCLIPKSVGSNSTKEYI
CPYCVLVDSGSICRSKDSPLRYKGKRPELEKLVELSSDAKKFATRLEESDLLQEILDEAL
ACRDCLSGVVDSALSIFDNDVSSISGKLTIALKGLDVAGVCDSVAIRKFDQALARNSWRI
RAFKLVDGSQKPVMQQVQRHLKEGSAISVPPEDYFRQKLIGMKEAGMRWVEMAKKVSSDS
GDLELDKVFELIAEGEKLPIHFEKELKLLRARSVLYCICRKPYDQRSMIACDECDEWYHF
DCVNVISPPDTYYCPACKPRMEGKMPMSPSVKQERSQSAKDNEPQTPSPRHVESRWRPKK
RKPSMKRKVFVAADRKSLLWSSGFDKLLWRNKKPFRRTVKKRTELGSLSPFFLLQQ
>Sgl57295 ULD/UDP/UBQ/UBQ_Other 36.5 0.0
MMGTMPILPLPAPPEDGNLGPTPLSQLPPDHDEKKEVDDQQKSGKPDSVATHTRTIGIIH
PPPDIRNIVDKTAQFVAKNGPDFEKRIIANNAGNVKFNFLNASDPYHAYYQHRLSEFRSQ
NQSTVQQPSSQLDSEAEAVAAAASDGASAAAEKPDPAAQFRPVRKVLEPPEAEQYTVRLP
EGITGEELDIIKLTAQFVARNGKSFLTGLTSREMNNPQFHFLKPTHSMFMFFTALADAYS
KVLMPPKGLTEKLKKSIADRTVVLERCLHRLEWEKSQEQARQKAEDEIEQERIQMAMIDW
HDFVVVESIDFADDEDESLPMPMTLEEVIRRSKITTKDEEEIIEPGKEVEMDMDEEEMQL
VQEGMKAATLEENGEDKTNEVKADMDEDEAPMRIVKNWKRPEDRVPAEKDPTKFTVSPIT
GELIPISEMSEHMRISLIDPKYKEQKERMFAKIRETTLAHDDEISRNIVGLARTRPDIFG
TTEEEVSNAVKAEIDKKKDEQPKQVIWDGHTGSIGRTANQAMSQSMGGEDEANNDGRPLP
GPAAPPPPRPPVPMIRPLPPPAGLAVNMPRVPTSNVQYSAPNSAGLMAPPPPRPMVGVNQ
MVPPPPPPMQMAPGQQHMMMNRPPMPPGSMNQSGMQVPPAPGSQFTPLGVHRHFTPVPPH
GMPVGPPQPMSQGMPPPPPPPPEEAPPPLPEEPEPKRQKVDDSALIPEEQFLAQHPGPVR
INISVPNIDEGNLKGQVLEITMSVNETVGSLKEKISGEIQLPSNKQKLSGKAGFLKDNLK
LAYYNVGDGETLSLSLRERGGRKR
>Sgl57322 E3_adaptor/Cullin_RING/DCX/DWD 25.7 0.4
MNSLIDSQNPKSNSSSSSNIVTLNVGGELFQTTQQTLTLAGPNSILSSSSSNSSSNSNSD
IPFFDRDPQLFSNILSLLRTGNLLPNFQTVDLPNLILESQFYGIEHLLTDCLSNPSQFNP
LNLQNSLILPLNGRDFPSVISSTSVGSVHVAHGCKITSFDWSLTRKSTVLTQFVAIDSLV
ALSPDLAAAGATDFSGLQIIDLEKGSVKENLNWVNSTRSSSTVQAIGSSNEHLFTCFESG
RRNSNAIVVYDRLGDFRPVFEIARNEIYGAEFDCSTIPATKLSWVSSYNLLMASGSHSGP
TGVSGSIKLWDIRSGNVVWEMKETVDCYADVSVSDSSSCMFKVGINSGEVFFLDLRNLTP
ESEWECLGNRAKLITSKKEGLGCKVECHGSDVFVSKGGNLELWSQVMVKSTRSGENVVDD
RVFKRTLMGRAKDMNGNRITNLRFGGNKMFVTRKDEQFVEVWKVSN
>Sgl57333 UBD/UBC-like/UBD_UBC 100.8 0.0
MSSPSKRREMDLMKLMMSDYKVEMINDGMQEFFVEFHGPTESPYKGGAWKIRVELPDAYP
YKSPSIGFVNKIFHPNVDEMSGSVCLDVINQTWSPMFDLVNVFEVFLPQLLLYPNPSDPL
NGEAAALMMRDKAAYEQKVKDFGSCCMRILATSNLDRSGVRMFPVALGRNREGGGGLWNL
DQLTRPVERLSSSSFSAVLLFHDHTKKLSHFPEYCEKYAKLEDIGAAQEEEISSEEELSE
DGYPSSDGDDEVAGKVDP
>Sgl57335 E3_activity/RING/RING 31.5 10.2
MVGCCCCCFPSRRSEPVRTPTYYYCPRTSEEREPLSANHGIPPGLGGGLLVDTNLDTSSL
DTYISPPAPIPYDSDLGRPRTPLGRDNNLSKSNTSAGVANSGSEEGLNNADSIENQEKVM
KELDDKAQSVLDLNLSEDSDDDLKKGVEANLTIIEEEDCPICLEEYTEENPKMVTKCEHH
FHLCCILEWLERSETCPVCDKEMLIDEAFNL
>Sgl57343 E3_activity/RING/RING 26.6 9.7
MGFPAGYTEVLLPKLLLTTLSLLGFVRRFILSFLRLMGLSSLVEPATEPDQPDPIPAQSV
SSAAALIREMLPAVKYSEIAPSSGHCGPEDEPGLTESCAVCLYEYEGEDEIRRMRNCRHM
FHRCCVDRWIDHDRKTCPLCRKPFVPDELQEDFNEKLWAASGIPDFYSEYSPITNFL
>Sgl57344 E3_activity/RING/RING 31.9 8.1
MGFPSGYAEQMLPKFFLNSLSLLTFVRTLILALLKLIGLSHILEPQICWPEPEPDYRPVS
ASIIQEMLPVLKFSEVSSGQPKPEPGPCDEHCAVCMNEFRDHEEIRQLTNCRHIFHRVCV
DRWMDHDQITCPLCRALFVPDDLMESYHEKLGAATITAAIPEFGGEFSVINSFL
>Sgl57347 E3_adaptor/Cullin_RING/SCF/F-box 21.1 0.0
MADLLPTIPCDVMFEILVRLPVKSLLRCKSVCKDWYNLINTSTFVEHHLKQSINNSHHLC
HRPRPFVFASRKSLYLGEDIDFPKKLIELKLLFKDNENALLEYDDAHMIGLCNGLVCLRL
GSTPKYFAICNPLTRTCKVVASHGEEMGHNLWYPVYGFGYDTQTDDYKIVVITMGRDRQI
WIYSFKKNSWKKGSSDRLHQPPFQQNIYHNQLAYGVFGHGMLHCIVRGVEDGIRPILGSV
DDFMYKELPQILRFNFSSEDWEEDLSFPNLSNNLSEYMYVEARILDGFFCIATYDLWEKL
NIWIMKEYGVEKSWTKLYNCDLSSYNLIAFSRTRPNGLCFNTRSQGLVWYDPKQETKELF
EYDSPFKNVFHYEVTLCGQSLVSIPGSSYMTREEFQAKV
>Sgl57389 E3_adaptor/Cullin_RING/DCX/DWD 36.5 11.4
MAMRCRSIVGIWSETPPSHRITAVTTIDEPPTLYTGASDGSVVWWQLSSLTIKPVAMLCG
HVAPIADLCISYPLLASVDENSNPSRDVGHNSLPGDQAALISVCIDGVVCVWSRGSGHCR
SRRKLPPWVGSPSIIRTLPTNRRYMCMASCFTETSQTSESDFVDSGEGNEVTGNEESLGR
KPPKCTVVIIDSYSLNIVQTVFLGHLSIGPLEFMEIVEPVADSQKHSILLIDSYGNSQCI
PLVKDSHLNEGEPKLHQNSSLVNTAPLKNGPYEGEMVLCVSTYGQLLGLICKTRCIFLLV
SSDTVVGVLSLKDNSHHGVDCTLSHVTGGMFISSNNTSISESGKTHMFGLKFSVWDDRGS
VVIYELSYVNDIFKYEISNEIPAITCPIDVKVSIKIVQLSNYFLRVESICFRNEEPSLWR
PHVTIWSLHQQLDDHESFGKNCRLLGEGNFLVDWVDYSSDAINNEAPENTSGEKSATGGP
SNSSYKNNLNCTSVWKESIVSSTMVISLNAHTPYAIVYGYHSGQIELIQLNFLAPKIDSD
AVNLHPELECLGSKRHFSGHTGPVVCLAAHLTVGNSTERASKKLLLSGSMDCTVRVWDLE
TCNAIRVMHHHVAPVRQIILPPLQSYHPWSNCFLSVGEDSCVALVSLETLQVERMFPGHP
SYPLQVVWDSVRGYLACLSQNNSVTSGTKDVLYIWDIKAGSRERVLRNAAAHSMFNNFCK
AKDTNNISGFASNYNTSRSSFIFSLTEDGSSLSSKMENNMSISSSVVNPLDRCMSSINNS
SARSVKLSTGNYDKHAIRCSCPISGIAILNFDLSDLLSTDICGDGENHFRAPSNESQQRT
TSYDSSEQGNFQKIMQDDQCVETFKLCLLQFSLSFLHLWGVDAELDHLLEMEMNLKRYEN
VMSAPGLEGDGGSVTLAFPAFSSALQLWQSSSEFCAMRSLTTVSLAQSLVSLSHSCSGAS
SALSAFYTRNFAEKVPDVKPPSLQLLASFWQDEDEHVRLAARSLFHCAASRAIPPPLCCS
RTTEHTKTADHVDQVGRSEREYQKRTETGAGFLLAERPETLGDSQVGEAEMMKWLESYEL
QDWISCVGGTSQDAMASHIIVASALAVWYPSLVKPSLSVLVVRPLIKLVMSMNEKYSCTA
AELLAEGMESTWKECIGGEIYSLIEDIFFQIECVSGASTNTPSAAAAVPPKLRETLVSIL
LPSLALADIPGFLSVVEGLIWSTASDSPVHLVSLMTLIRLMRGSPRHLALYLNKVVNFIL
QTMDPANTVMRKSCLQSSMATLREVVRVYPMVALNDTSTRLAVGDAIAEVNSANIHIYDM
QSVTKIKVLDASGPPGIPTFLSGAPETVVSAISTLNFSPDGEGLVAFSEHGLIIRWWSLG
SGWWEKLSRNFIPIQCTKLIFVPPWEGFSPNSSRASIMANIAANGRHSQVHTRSSDIDSL
NLLLYNLDLSYKLEWVVDRQVCLTRHGQELGTFLL
>Sgl57390 E3_activity/RING/RING 21.6 4.4
MSVVQIAPNQTATPTNDDVSGKSQTQLALELNSCRIIAVAEQLLMCAQSGDQPFKVHQLC
LSLARGIDYGLANNEVPAAASQLPQVLKMVCSRKNDVNLQAGIMVLMISVKNACKLGWFT
ANDTQELLTLADEVASYFVTKKDTGVCNSLPTVSTIMSRFYPRFKLGHVISFLEVEPGYG
THLVDFHISKDVAFSKEERIRLFVAMKDNIDTSSCIITPQQVNILLNGKPVEHRNSVLMD
HGPQLPTVVNPSLKYGINLLQVMGQFNGHYILIVALMNVIPSSDLQPPVDYVQPASAASS
SDAEIIEGSSRVSLRCPISKTRIRTPVKGSSCKHYQCFDYNNYVEINFKRPSWRCPSCNQ
SVCFTDLRVDQKMVKALKEMGENVSEVIISVDGTWTPASSDKRKDESHHKTSANQQEGQV
LEVSSGMLDASDNMCDLTGEDDEMDTDSRSEPVDTKPVIHHHAQGQSAPSNCTLPQASRS
TIEVAQYSSGQVVNSASPRTMFNSGSAGFNFRPHAQLGGTSRTLTGNGGVTPVLTDAVSP
ALNRQPDNFQGTNCSPSLNRQLQEALFSPGLMNNNLHLIPRNVTRVPNAIQALPVPTTPQ
QHSRPTVSSPTGSGSTPFQRSVAGSNARAPSPYSSNVERQRHLSQSFAGSHMSNMPSLQP
LNRSASPGVGISNPSHNMPMPQTLSQPPHLMRTSQLPPANQTQAARMMSSLPLNSGVIPQ
AVSRTESLIDLQAEQNWRPSGRMRGALTGKAYSDALNQFMGQAAPPVQTQSPRPTVSQSS
TPPIVNNILLANRRIASEVQDRSGAGSGTVNTQEEGSG
>Sgl57413 E3_adaptor/Cullin_RING/SCF/F-box 19.2 0.0
MDMEPGPSWEDLVLQVSEENHTSEPNVVDSFVGLTYVDDENKDVVCINSILPDDILEQVL
GHLPISTVIRAGSVCKKWNDVSQTGRFIQNLPNTSPQKPWYFMFTGDSDPLGHVYDPILL
KWFRFEIPYVETSSWYIVSSSGLMCFMDNDSRRKLYVCNPITKRCRKLEKLSSVEVSDYC
ALAISLDKSSQNYIVTIVRSIQAPTEAMDWKLSIDVYSSENDSWACPVNVTLQDWRGGFD
SVICGRVLYFVVYQTRTMGFIRPRYGVMAYDLASESFDLDMDEPIIRAPCPITCMRLMNL
EEELVMVGGIEKQGRPGIIKGIGIWVLKGKEWEEVSRMPNKLFKGFGEIDDVFSSSGFNK
LIYIQGYGSPALLMFEMNSKEWSWAHRCPAIKKFPLQLFSGICFEPRLDVSP
>Sgl57414 E3_adaptor/Cullin_RING/BCR/BTB 32.2 0.1
MASPNDSNSTDNGSVHNNSVADPLFISNSDNPTHSLTNVVFSGVNFVRWKRNIHRALGAK
NKLGFLDGTIAVPDESNVLEYQKWKRADYMVVCWILSSMNGELADDFSYAESAVELWHDV
CERFGQSNGPLIYQLRKEIDALKQENLSILSYYGKIKRLWDELQSLKSSPMCTCGALNSC
SCNFLKRLSDCESEDKMMQFLLGLNPVFDSTISQILSMDPLPTMNRAFSIVQQIEKQKEI
SATHDGAVPESSAMAVQRFNKPFGAGRGGYQQMNSGRKDWRKDKMTRFCDFCKGKGHFAD
QCFKKNGYPDWYTSLKGGKPAVAANAAVTDEAIGDSPLDSGSNSHGVDNSFLNSVCQEVI
KAMQGKQLSESGGCSSFANCAGTIAYSLSCNTIGCVDKMTWIVDSGASDHMVCDSSCLTS
IRKLDVPIRVGLPDGSCKMVNVVGSVKVNDKFVLHDVMLVEGFKHNLLSVGKLLDTSSIN
VQFTRNGCIFQDHSSKVVAEGVKVAGLFLLQNNQATAGAKISASSSTSCNNVSGDLSKIP
LDIMHSRLGHVSLSKMKYIPGCNCSGLKSYDCEICVCAKHHKLPFNKSMSRADSAFELVH
FDLWGPYKIMALDGSKYFLTVLDDYSRVTWTFLLQNKLQVAKTISNFLAYVANQFGKSVK
VIRSDNGTEIIKEQCLSLFLEKGIVHQRSVPGVPQQNGRVERKHKHLLEMSRALRLNASL
PKKFWGECVLTSTHLINKLPTKVLNWKTPFEVLFGKVPMYDNLRVFGCLCFAYNKNSKSD
KLESRARRCVLIGYPFGQKAYKLFDLESKVTFVSRDVTFQESIFPFKTDNALLPISPKKA
PTLISFGSFEPEFLPTPPTSSAPISQLLPPTDSSVSTSSQSFSTAVPVPFTTEIPISSSQ
TQAPVKSSRVVNPPAKYMLRVQLSLVTEQQIYSISKEKDYETYSTSTTITGSGDETLQNN
DASLNMDCLVEVKTIHISSPILAAKSPFFYKLFSNGMMESEQRHVTLRIHASEEAALMDL
LNFMYSNTLRTNTPPGVLDVLMAADKFEVASCMRYCSKILRDFPMTSESALLYLDLPSSV
LMADAVKPLTDSAKEFLASRFKDMTKFQEEVMNLPLAGIEAVLCSDDLQIASEDAVYDFA
VKWTRAHYPKLEERRNVLGSRLCRLIRFPHMTCRKLRKVMTCNDLDPELSSKLVTEALFF
KAEQPYRQRALLADETKTSGHRYVERAYKYRPVKVIEFDTPRPQCIVYLDLRKEECQKLF
PSGRVYSQAFHLGGQGFFLSAHCNMDQQSLFHCFGLFLGMQEKGSVSFAVDYEFSARQKP
NDEFVTKYRGNYVFTGGKAVGYRNLFGTPWTSFMADDSLFFINGVLHLKAELTIRQ
>Sgl57429 E3_adaptor/Cullin_RING/DCX/DWD 87.4 14.4
MDEGYADDVTAVSQAEDVPAQGKDQVLVESRNVLEPRGRVITGEGNMRRSSIQQFVDILG
GQDASSSVNIVEIPEGPCSSYQDAGEGRVQELTLGNYTTGFNTVNEGEMMNTILNEWQHG
NQTGLGSEAETTNEHPTHKEKSSRSSALRDSRPANVLDGQGFNHEASSSPGRDDCDAVLQ
HAFSSGPMRMKILSRSSECPEYFVKDTLKGKGILCRGPTSAGEYKGQNTVKAVAAPMLAS
NPSVKIGENFVIPSKCGNVASYGNKSVNAGTNLREWMRSRQKLLNKVDTLDTFKQILDLV
YLLHSDGKVLVDLRPSFFRLLPSKMIQYSGRVCAQKEMLGNVTHKDFHKSHPRKRQLEQG
MSPHTYLSAKHQKSIDKANFLKMKSQFQLGYGPRPITNKVDANLAGAGPADSKISSRLHL
PPSAQQHAVFAEEQQEEKWYRSPEELLGRDCTSSSNIYSLGVFFFELLSSFDSVKMQTTV
MSDLRHRILPPNFLSESPKEAGFCLWLLHPEPSLRPTAREILQSEVMREIALCGDEKSSS
IQEDEGESEMLLHFLLSVKEQKQRHAAKLVEDLGCIESDIKELENRHLKNSVIVSSTGED
LLYARQRDFLFHENGLPNPVSDGGDSRFLKNAVQLENAYFSARSQIHHSVIDSRDQDDRG
VLTIRDDWNSNQNEEQKPLDDRGAFFDGLCKYARYSKLKVCGTVRNRDITNSTNVVCSLS
FDRDEEYFAAAGVSKKIKIFDIQALYDNSVDIHYPVVEMVNKSKLSCVCWNNYIRNYLAS
TDYDGIVKLWDANTGQEISQFTEHEKRAWSVDFSLLDPMKLVTGSDDCCVKLWSINERNS
LHTIRNIANVCCVQFSPHSSHLMAFGSADYKIYCYDLRNANSPWCVLAGHEKAVSYVKFV
DSGTLVSASTDNTLKLWDLSKTSPVGLSNNACSLTLEGHKNEKNFVGLSVSEGYITCGSE
TNEVYTYYKSLPMPITSHKFGSIDPISGKETDECNGQFVSSVCWKGKSNVIVAANSSGCI
KVSDCISLIVWLRFGAFPIQIHSIKGRNCKNHLKGMTIRYLLFIP
>Sgl57449 E3_adaptor/Cullin_RING/DCX/DWD 37.7 5.2
MEKKVATLEKGTLCSAWNYSAQRLASASINGFLTIFDSPDSASSSPFSPSSSFQVHKGSI
LKVVWVPPEFGDAVACILDDGTLSLWEEVAEDGKSLQWKFCTKFHNDGARVLDIQFGGTS
TCLKLVAAYSDGYVKIHELQNPLELNTWQLQAEFQNVIDSVSKYAKVLCSSASISWIPQR
GENQQLSFVLGFSSDVPQLNSSKVWEFDQLHQRWLSVAELSLSENSGDPVYAVAWAPNIC
RPYEIIAIATEKGIAIWHIGLNPDVNGHLSAENIALLSGHKGEVWQMEWDMSGMTLASTG
SDGLVRLWQSNLNGVWHEQAILEPAS
>Sgl57481 E3_activity/RING/RING 28.9 7.2
MNQYSLILSFFFSVIILSDLTPSQLCSSTSIDCSSQPSFQTHFPFRIPEFETTRCGYPGF
ELSCSSNGSTILSLPSLSQPLRVESISYEHQYILLSDPNLCTPKWAMDLYLVSTPFIVEP
SNAVNDEPRYYAFVNCSGPPLMNNAVPFGSSVISCMSGGDYTIVATLRNDAEKIMVDRGC
QVVKRMSETEFWWEGKMMNDVENYPQDFSQVFLLLSWDEPDCSACTGNGSSCGFAADSGL
DVACYNAGAFADGIIPTHSKWDYIVLDIVFPLSMLIVLLSILIVCCNPNTNTESSRYEFP
QQMLPRLGLDESIIESYPKTVLGESKRLPNNLGDNICSICLSEYEAKEILRTIPECQHFF
HADCIDEWFRMHTTCPMCRNSPQPSPALAA
>Sgl57495 DUB/UCH 265 0.5
MQTSKVILIMSWCTIESDPGVFTELIQQMQVKGVQVEELYSLDLETLESMRPVYGLIFLF
KWRPGEKDDRAVVKEPNPNLFFASQVINNACATQAILSILLNSPDVDVGSELSNLKEFTK
NFPSELKGLAINNSEAIRTAHNSFARPEPFVPEEQKAATKDDDVYHFISYLPFDGVLYEL
DGLKEGPISLGPCTGGQGDADWLRMVQPVIQERIERYSKNEIRFNLLAVIKNRKELYTVE
LKECQRKRERILQQLSSIQSGVTDNSKLEELNKQLAEVNSGIEAATEKIVVEEEKFKKWK
TENIRRKHNYIPFLFNFLKILAEKKQLKPLIEKAQQNKVSNSS
>Sgl57499 ULD/UDP/UBQ/UBQ_PIM 91.8 1.0
MSGGVGVALSSNYEDMVHFPGFFENRVDLHPSESILVYLSVAGSVIPIRVLESDSIASVK
LRIQTCKGFVVKKQKLVFGGRELARNDTLVKQYGVTSGDVLHLVLKLSDLLSIIVSTTCG
KEFEFQVDRFRNVGYLRQRIFKEGKGFVDLKNQELFCRGEKLDDHRVINDISKTNDGTIH
LLVKKSAKVRAIPIEKDVELSVVASDIRPRDNKSDESEKQSSELCAAVSRKHPDRDFWFE
PVFGNPTVKLPLALSNLINSTFDGLGKGNQPIRSTEGTGGAYFMLDSSGQRISAVFKPTD
EEPMAVNNPQGLPVSENGEGLKKGTKVGEGALREVAAYLLDHPKNGPRSSSSREVIGFSG
VPPTAMVRCLHKGFNHPNGFEGTLKDVKVGSLQMFRENDGNCEDIGPQAFPVEEVHKISV
LDMRLANADRHAGNILYKKNDNNGQIELIPIDHGYCLPDSFEDCTFDWLYWPQARQPFCS
ETINYIKSLDAEQDLALLKIHGWDVPTECARTLRISTMLLKKGAEKGLSPFTIGNIMCRE
TINNESMIEKIVSEAQQSLLPGMKEEDFLEAVSQVMDHRLAEMF
>Sgl57503 E3_activity/RING/RING 20.2 11.3
MEVELFSNNVLSEEDTVEVDTEFDNLGDEGERCGICMDIVIDRGVLDCCQHWFCFVCIDN
WATITNLCPLCQNEFQLITCVPVYDTIGGSKNDEESDSRDDNWSVEGTNNTLSFPSYYID
ENAVTCLDGDACKIRNGLVTFEETLTLDTSIACDSCDIWYHAFCVGFDPEGTSVDSWLCP
RCLVNEEDQNSDLKELYCTGKNDDEHCFVDTSTGKVSIRVADSGETAVVVSRINGENLTG
EPNVNSLSNQELVGLDPDCCTAEMERPLDQGNEGIDTFKPESNLPFSRLGETVIKCEPEE
YESKMSFDAELAFAPTLSDDKALLGQDENMEDVKADVGPKLGAKRKRPGNSFRKNSDEEP
HEGRLVGSSSTKKAKAQRRTRSTMNDQVDVCEEFKKNNKAIDSSADEIDRNITMKKNQPI
DIMSIVQGTKPIAGNRSVSKKEAGKSAKVEKNAAGLRVKRIMRRPTEEKESDAVVQKLRK
EIREAVRDKPSDEIGKSIFDPNLLTAFRAAVAGSVSEPAKKSTSAMVKAKKLMLQKGKAR
ENLTKKIYATSSGKRRRAWDRDCEIEFWKHRCRTTGKPEKIETLISVLNLLKKSPGTKNV
DQTSEEEAKAPILSRLYLADTSLFPRKDDIKPVSALRAAACSNHNDKPSTLDKPPASADD
KKSVCTSTKNGSASESLHSAGQPNKASPQKKMTGKTDDVKIDKRKWALEFLARKSASDVS
SPIHKKEDNAALKGSYPLLAELPTDMRPKLAPTRQNKIPLSVRQVQLYRLTEHFLKLTNL
SIMRRTAETELAVADAINIEKQVADRSNSKVVYLNLCSQEIRNFTNCSSPGTLGKSTTTS
STVPVLSKGDSEFTPPSSIPIPSTGGQTSTLSLNSEADAALRAAGLLSDSPPNSPLHEAE
YLNGDDNAKGETKEEIDNIFEMNSHPDLDIYGDFEYNLDEEDYIGATVINASKAQAEDGE
SKVKIVFSSLSSIKSDSASEANEQGLPKTDLLLSTPSLLEGPNDVDSGNSPLEDKVDSIS
LPGVTTLDGEVEELSVAECEALYGPDDDLANKNISDLAPAEQFALTGSTNVDVISDKDKV
TTDSLQSMTAGEKSSSSLNPKGNDDEEKNSNRKVDKKDEHGDSVLKKVEAYIKEHIRPLC
KSGVITTEQYRWAVGKTTEKVMKYHTKSKNAYFLIKEGEKVKKLAEQYVDAAKHKAK
>Sgl57507 E3_adaptor/Cullin_RING/SCF/F-box 15.2 0.0
MEVTLSSFLSSQSFIVAFAATLLCGIFAVRFSLSSSSKIDSSRRKNFTTESKDSNSSNNC
VSDCNCSCNGVVLRPDPTVAAVNGGEMPAVAMVAAEKQTGASMMEQLVPEITTHALSYLD
YPSLCRLSMTNSLMRKAANDDNAWKALYHKDFTVEQDSVRPANGWKAYYAATRALVNINA
EFFNIIRERSLPAMSRFWLNADYVKCVHVSGELITGYNAVMQSWQIAFNWNQETDGFQIR
DVRARVLTDMAWITMKTYVGMNGGPYSVTNVFEHHNGKWYMVHHHCSLMLVDEDVEQQIV
HG
>Sgl57532 E3_activity/RING/RING 35.1 10.3
MGRHEDSIPPNSSLYPEELQLKLYQAFIFSIPILFSIILFLLFYLFYLKRRANNNLLAQT
PTTQHSALHSVSFLATPWSLGIKGELKDKLQVILFDEELRERDTICCVCLGEFELKEELR
QLPLCKHVFHGDCIRHWLRNNATCPLCRCPVLSGMKMDCPVGLRQDLTSQENDNNLAPQQ
QEQENVASSTSEVHNSSSRSEVHVIQIVDEPPSSSSSSNHAS
>Sgl57573 E3_adaptor/Cullin_RING/DCX/DWD 76.7 9.7
METACVESDAFYDAPEEISSVSDSESEDSDELQQVGNNGISSLHYDFWSGNPKSIDERRD
DFIRRTGFVLDRCQTAREGPDDATCVTSGMCNDRTESVENEHDEGKELTAGVIQEVVDGG
DQGLLWRIQSLDDRKEFDVENEGIASRKDNAAGVSSRAAIDEFHTAFGTSNLFQQTKTKS
EENGTVCKKKPQCKEGWLKRFSFKAANMFNKDKDHKELLQKCKSLGYRSQRVRVRSHKKW
SKELSSLYRKQEFSAHKGSILAMKFSLDGQYLATGGEDGTLNVWKVIEDEMLTDLDLLRF
SPVSANLNFSVNGVPNLACFLKFKEGRKVINKLKKSLDSEGIMIPRKVFQIVEKPLNEFH
GHEGEILDISWSNNGLLLSSSIDKTARMWKVGCSQCLRVFPHHDFVTCAQFNPMDDSYFI
SGSIDGIVRLWDIQRGQVIDWIDIKEIVTAICYRPDGKGGIVGSMVGNCSFFEIADDFLH
QVSVIYLQDKKTLTCKRITGFQFSPNNPSEVVVSSADSLVRILKGADIICKLRGSLPLID
RGSQVFASFTADGKHVISATDDSNVYIWNHLNKGRITNNKPKNVWSCESFLSQNAIIAVP
WHGITSTSALPPSTPRQPTSTSKYNQKSPVSSSYHTVNHAEVSSMKSSATARDCEALLRS
NQADISPAIGDMEYEFLKNVCEGVLSGSHMWGLVIVTAGKDGRIRTYHNYGLPVRYPTRK
FSLSNIRNRCRENCSNIKGSTSLGR
>Sgl57582 ULD/UDP/UFD/UBX 59.9 0.0
MVDSNDKLAYFQAITGLEDTDLCTEILAAHNWDLELAISAFTGNHDSNPLPSSDVGSSGQ
SIPTSSSNDAVFPPEPNPGNPGLAWRIITLPISVVSGSLGLISGAVGLGFWAAGGVLSYS
LGMLGLGARRGGGPASSPLVEGTPSSAEAMEFVAAMEREYGSLLKVNFVSEGFMDALQRS
RHAYKLLFVYLHSPDHPDTASFVERTLGNEAVAEFVNENFVAWGGSIRAPEGFKMSNSLK
ASRFPFCAVVMAATNQRIALLQQIEGPKSPEEIMSMLQRVLEETAPVLVSARLEAEERRN
NVRLREEQDAAYRAALEADQARERQRREEQERLERERAEAERKRQEEEEAREREAREAAE
REAALARRKQEKALSLGAEPEKGPDVTQVLVRFPTGERKDRRFSSSATIQSLYDFVDSLD
CSTFESYSLVSNFPRTVYGPEKHSLTLVEAGLHPQASLFVEPNP
>Sgl57584 E3_adaptor/Cullin_RING/DCX/DWD 76.7 9.7
METACVESDAFYDAPEEISSVSDSESEDSDELQQVGNNGISSLHYDFWSGNPKSIDERRD
DFIRRTGFVLDRCQTAREGPDDATCVTSGMCNDRTESVENEHDEGKELTAGVIQEVVDGG
DQGLLWRIQSLDDRKEFDVENEGIASRKDNAAGVSSRAAIDEFHTAFGTSNLFQQTKTKS
EENGTVCKKKPQCKEGWLKRFSFKAANMFNKDKDHKELLQKCKSLGYRSQRVRVRSHKKW
SKELSSLYRKQEFSAHKGSILAMKFSLDGQYLATGGEDGTLNVWKVIEDEMLTDLDLLRF
SPVSANLNFSVNGVPNLACFLKFKEGRKVINKLKKSLDSEGIMIPRKVFQIVEKPLNEFH
GHEGEILDISWSNNGLLLSSSIDKTARMWKVGCSQCLRVFPHHDFVTCAQFNPMDDSYFI
SGSIDGIVRLWDIQRGQVIDWIDIKEIVTAICYRPDGKGGIVGSMVGNCSFFEIADDFLH
QVSVIYLQDKKTLTCKRITGFQFSPNNPSEVVVSSADSLVRILKGADIICKLRGSLPLID
RGSQVFASFTADGKHVISATDDSNVYIWNHLNKGRITNNKPKNVWSCESFLSQNAIIAVP
WHGITSTSALPPSTPRQPTSTSKYNQKSPVSSSYHTVNHAEVSSMKSSATARDCEALLRS
NQADISPAIGDMEYEFLKNVCEGVLSGSHMWGLVIVTAGKDGRIRTYHNYGLPVRYPTRK
FSLSNIRNRCRENCSNIKGSTSLGR
>Sgl57595 ULD/UDP/UFD/UBX 59.9 0.0
MVDSNDKLAYFQAITGLEDTDLCTEILAAHNWDLELAISAFTGNHDSNPLPSSDVGSSGQ
SIPTSSSNDAVFPPEPNPGNPGIAWRIITLPISVVSGSLGLISGAVGLGFWAAGGVLSYS
LGMLGLGARRGGGPASSPLVEGTPSSAEAMEFVAAMEREYGSLLKVNFVSEGFMDALQRS
RHAYKLLFVYLHSPDHPDTALFVERTLGNEAVAEFVNENFVAWGGSIRAPEGFKMSNSLK
ASRFPFCAVVMAATNQRIALLQQIEGPKSPEEIMSMLQRVLEETAPVLVSARLEAEERRN
NVRLREEQDAAYRAALEADQARERQRREEQERLERERAEAERKRQEEEEAREREAREAAE
REAALARRKQEKALSLGAEPEKGPDVTQVLVRFPTGERKDRRFSSSATIQSLYDFVDSLD
CSTFESYSLVSNFPRTVYGPEKHSLTLVEAGLHPQASLFVEPNP
>Sgl57655 DUB/USP 370.8 0.7
MTIPYYEHANSLDNGVICSPQEQKRIIKELNDQAESNLKEGNLYYVVSTKWYLSWEKYTG
QDNVDCEMNGSSPLQNGVDRPGPIDNSQLVSSVNESDVDNKDLIRTLEEGQDYVLVPDEV
WKKLLEWYNGGPSLPRKLILQGDTNKKFNVEVYPLCLVVTDSRDNSQSDIRLSKKASLLE
LYEKVCTLKGLPQEKIDIWDYFNKQKQCVLLPSNKTLEDANLQMDQHLLLELQNVGEGSS
GHGVSLAGNELALVPMEPSRSTVTIAGGPTSSNGYSTRSRSNVSPGLIFSTNVENGGHDR
LGSLSKKEKGGLAGLQNLGNTCFMNSALQCLVHTPPLVDYFLQDYVNEINKQNPLGMHGE
LAIAFGNLLREVWSSGQTLITPRPFKGKLARFAPQFSGYNQHDSQELLAFLLDGLHEDLN
RVKQKPYIEMKDADGRPDDEYAEECWKNHKARNDSIIVDFYQGQYKSTLVCPVCNKISIT
FDPFMYLSLPLPSMINRTMTVTVLYGNGNGLPMPYTVTVSKHGCCRDLIQALGTACCLKN
DESLLLAEVYDHKIYRYFETALETLSSIKDDEHIVAYRVPKKLTGLKRLEIVHQSPEKKR
LGSPLVTYMHEEPQNVADVCTAITTILSPLKKAVVSSNRNHNEKNNGSASSANNEADNGL
MDNTADDSNFPFQLTVTEDNLSSGKIIDDDYVKNSPLLKVTLHWTDSELDNYDISYLENL
PDVYKSGFSAKKTRQEAVSLFSCLDAFLKEEPLGPDDMWYCPNCKEHRQASKKLDLWRLP
DILVFHLKRFSYSRYFKNKLDTFVSFPIQNLDLGKYANKEASNGPYVYELYAISNHYGGL
GGGHYSAYAKLIDEDRWYHFDDSHVSPVSESEIKTSAAYVLFYRKVKVEANYEAR
>Sgl57689 E3_activity/RING/U-box 26.2 0.4
MAVYYKFKSAKDYHSIPIDGPFISIINLKERIFNSKLHGKGKDYDLVISNAQTNEDYLDE
AMLIPKNISVLIRRIPGPPCKPIVTQPDKPKVENQAVYDQHVKDNCKANDCSGSLDIDDS
EWNDLFGSSLYTTSASDAVPSRKSDEDNKIKAVVENSGLKQLNHHTLPGRRAGRVSRGFG
QGGWESKTPPQGYICRRCKVAGHFIQHCPTNGDRDYDIKKTLIGIPKPNEALFEKEMEGL
PSTHCRGDLPPELHCPLCNEVMKDAVLTSKCCFGSFCDKCIRDNIISKSMCICGAREILA
DDLIPNMTLRDTISRILESGSSSANSGRSGLRVQASTHSPQPRISPPTQSAASKGDQMVP
SGAKETPNIKENVDGSRHNDASQQPVQSSGEVKIAKVPVLPNVSEAAPESAVKKVESAVE
EGQQKVAAVESGKKKKIKKMPNPATAADMGWSGMQPFMDGYMDPSAYNTYWPGMQPAVNE
FWSPFGGNIPYNMGYGFGPFGDFIHPYPSGAQGFMNAAMLSPWQRDIPQNRDSGREPSSI
PSIQSKHNQAPARRSPSKGRYIHHHDHDHGHKNEQKRSSPGHLRSQSKPSFSTLQPSEAS
SDKNHRKRGLVRVESEVRRTKPRQECVV
>Sgl57701 UBD/UBC-like/UBD_UBC 95.3 0.0
MENSLQNALQKTAIPETTDQLLRSNKKPKRNFTNFFFNDNQPNDVDMADNTPPPPEAQIQ
PPPPPIHPTVPPRSFSQMVQGNFNSIIGASDTADDDFSDDDEPPEDFVNNDKCPAILLTK
EEKKRIRQPWKNSLIIKMFNSKIGYMSLMKRLKKKWQLKGGLILTDIGYDYFIARFSSME
DFNHVLTQGPWMLDDNYLTIRKWVPNFIPDDSPIQFLTAWVRIPNLSVEYFDMEFLKKVG
NKIGKVVRIDKTTASAERGQFTRLSVEIDLSKPLLSKFWLRGKIWKIQYEGLKMICYECG
KIGHKAENCPLHHEDPEVEVMETNANPVEAPPPPDQSPHKPEEINTFGSWMVVKKPAARK
RAPKDGHDKAKQGAAPNSKPKSTAEVNVVNGGSRFDILENIQNENIPNNITSNMAENMGE
SSSKEKSNLNFPPTQFPTVNLGENSQQPSSANIFNLGKNVMNPTFHATSSTAAKIWKEKI
STSKNKLKKPLQEITNLTHQVSKNLNVNASLPSQKQAVEIESTHAIAKEPSQATESISHT
SPAQSLNSQIIENSSSHDIDYVPPTPTTPHISHLISLSLFCTVCCIYLLKNRNWKRNSRI
HQKPRFAGKMINLFKVKAKQKETAENLNGKTPGKKQTAGELRLHKDISELNLPKSCTISF
PNGKDDLMNFEVVIRPDEGYYLGGTFVFSFHVPSVYPHDPPKVKCKTKVYNPNIDLEGNV
CLNILREDWKPVLNVNTVIYGLYHLFTQPNYEDPLNHEAAAVLRDNPKMFESNVRRAMSG
GYVGQTYFSRCIS
>Sgl57767 UBD/SH3 40.8 0.0
MEAIKRKANKFKEQVAKQQQALRRQFGHFGADAFLVEEAEIACRDQLHKLYTSTRAAKHF
EKDIVHSIEGIISVTSKQREFDRKFAEDCCRYEAESRCSNSPLAEAALQVGTSRSSMVEE
KETLLGIFNEKVCNSLRTLVRSAELEDARLLVRRYDKLWNEVETQAAEVLKLRSKATEGA
KSEENFAKLELAEDKLDDLKSRLMALGKEATSAMLSVEAHQQNMTFQQLVVMLSAERYYH
QNVLSTLEKLLPEMLRLEQMSELVLPEDATQNQLHALETERNPDSNGSKEHEDDAYVAKV
VHPFDAEAEGELTLLIGDIVVVQQSILGGWSKGECNGKTGWFPSPYVQRLDEVSEGNVKW
ANL
>Sgl57821 E3_adaptor/Cullin_RING/DCX/DWD 95.7 9.8
MEEEVIMASSSMDGGVGCWELKSGNEKLRYKSCLSPPHSLISVGSRFFASSQLRASSSSG
SILYWSWHKPQPEVKSFPAEPIKPLLSNREGSYIIGGGASGNIYVWEVFTGRLLKKWYAH
NGAISCLTLSDDESLLISGAEDGGVKVWSLFMMFSDDRRKKARNDHVHSFRDHTLRVTDV
KSGHGGSNVVIISASEDHTCKVWSLATGKLLRNIIFPSVIDAIAIDVGEYAFYAGGRDGK
IYITALNASTTCSTDYGKHIIGSLANSSRAVTSLAFCADGISLVSGSEDGNIRIWDISTR
NIVRMFRHSKGPVTNVLVTCVSETMKSQALAGRKTLFIPPSLEKYANSSEEVVGSKVFIG
CDSMSDSATVSYLTEHVLNNQIKEIQQKGSTAAAEMEVERLKLESKRAMQMVEQWKKMYD
NLHQFCVNEIVDDSEAKLSCVNSG
>Sgl57880 E3_activity/RING/RING 18.9 4.5
MECLHRFCRECIDKSMRMGNNECPACRTHYASRRSLRDDQRFGQLIAVLYPDIRKFEEEV
MYELEDVDLQKICYEVPPKRKEKEMAFYDEDEARNKQIQESITQVLIKQSEALGKKCSSN
KDAAGPSVTRSQR
>Sgl57899 E3_adaptor/Cullin_RING/SCF/F-box 13.8 0.0
MLSCKRLLFNSNKRKNMKKKKKNRANLTNNQKKNRANSINNQPSFDTAEEHEEEEANVFS
LRNSINHGVQPLGNFFLSSTSQNSRDIGLGNFKVVSDELVLEILGILDVNSLGILATVSK
SFYVFCTHEPLWRNLVLETLKGGFLFNGSWRKTYIAANFPCFDVSNVGFCGLSIKEFYSD
YLFQSWLCANLEMKPEWLQRDNIPRRKGISVEEFILKFEEPNKPVLLEGCLDKWVAKDVW
DKDYLIKTCGDVKFSVGPVEMKLEDYFRYSELTREERPLYLFDPKFAEKVPSLGKEYEVP
VYFKEDLFSVLGEERPDYRWIIIGPAGSGSSFHIDPNSTSAWNAVIKGSKKWVLFPPEVV
PPGVHPSPDGAEVACPVSIIEWFMNFYGATKDWKKRPIECVCKAGEVIFVPNGWWHLVIN
LEESIAITQNYVSRRNLLNVLEFLQKPNASELVSGTRDRVNLHNKFKKAIDAAFPGTIDQ
LVTKAEEQKKILSYWETVADSHTGGFKFSF
>Sgl57928 E3_adaptor/Cullin_RING/DCX/DWD 15.7 0.1
MKVYNLFEEETPQIFALCGQGPRSSLRILRPGLGVSDMATSPLPGVPNGIWTVKRNVKDE
FDAYIVVSFASATLVLSIGETVEEVSDSGFLDTTASLAVSLIGDDSLMQVHPSGIRHIRE
DGRINEWRTPGKKMITKVGYNRLQAVIALSGGELLYFEVDMTGQLMEVEKHEMPGDIACL
DIAPIPDGRKRSRFLAVGSYDNCIRILSLDPDDCLQVLSLQSVYSPPESLLFLEIQASTG
GEDGADHPANLFLNAGLQNGVLFRTVVDMVTGQLSDSRSRFLGLRAPKLFAVNVRGRRAM
LCLSSRTWIGYMYQGNFFLTPLTHGILEFAATFSSDNCAEGIVAVAAEALTVFTIDKLGE
TFDQTVFPLRYTPRKFVLQPKRKLLVILESDQRAFKAEEREAAQNECFQTGMDDNGNLRM
EYVDDNEFSDEQYGYPKAEVQQWVSCIRVLDPRTGESISCLELEDNEAALSICNVTFNDK
ECGTLLAVGTAKSLQFFPKKSFDAAYIHIYRFVDGGKLELLHKTQVDGVPLALSQFQGRL
LAGIGTVLRLYDLGKKRLLRKCENKLFPSTIISLHTYRDRIYVGDIQESFHYCKYRRDEN
QIYVFADDFYPRWLTASQHVDFDTMAGADKFGNVFFVRLPQDVSDDIEEDPTGGKIKWEQ
CKLNGAPNKLEEIVQFHVGDIVSSLQKASLTPGGVECVLYGTVMGSLGAFLPFSSRDDVD
FFSHLEMHMRQEHPPLCGRDHMAYRSAYFPVKDVIDGDLCEQFPTLPVELQKKIAEELDR
SPAEILKKLEEIRNKII
>Sgl57929 E3_adaptor/Cullin_RING/DCX/DWD 13.3 0.1
MYLYNLTLEKPTGIVTAINGNFSGSSKQEIVVGRGKVLDLISPDENGKLQTLVSVEIFGA
IRSLSQFRFTGSSKDYIVVGSDSGRIVILDYNKVTNSFDKIHQETFGKSGCRRIVPGQYL
GVDPKGRAVMISACEKQKLVYVLNRDSSARLTISSPLEAHKSHTLTYSICGVDCGFDNPV
FAAIEVDYSEFDQDSTGLSVAQAQKHLTFYELDLGLNHVSRKWSEPIDNGANMLITVPGG
GDGPSGVLVCAENFLIYKNQGCSDVRVLIPRREDLPAERGVIIVSVARHKSLSFILVQTE
YGDIFKVTLEHGEEGVSELKIKYFDTIPVTSSMCVLKPGYLFAASEFGDHALYQFQGTGD
EPDVESLLCYNDGLGNRRRLPASVL
>Sgl57935 E3_adaptor/Cullin_RING/DCX/DWD 25.7 1.0
MYLYNLTLEKPTGIVTAINGNFSGSSKQEIVVGRGKVLDLISPDENGKLQTLVSVEIFGA
IRSLSQFRFTGSSKDYIVVGSDSGRIVILDYNKVTNSFDKIHQETFGKSGCRRIVPGQYL
GVDPKGRAVMISACEKQKLVYVLNRDSSARLTISSPLEAHKSHTLTYSICGVDCGFDNPV
FAAIEVDYSEFDQDSTGLSVAQAQKHLTFYELDLGLNHVSRKWSEPIDNGANMLITVPGG
GDGPSGVLVCAENFLIYKNQGCSDVRVLIPRREDLPAERGVIIVSVARHKSLSFILVQTE
YGDIFKVTLEHGEEGVSELKIKYFDTIPVTSSMCVLKPGYLFAASEFGDHALYQFQGTGD
EPDVESSSATMMDLETDEGFRPVFFKPRKLKNLIRVDQVQSLMPIIDMKVYNLFEEETPQ
IFALCGQGPRSSLRILRPGLGVSDMATSPLPGVPNGIWTVKRNVKDEFDAYIVVSFASAT
LVLSIGETVEEVSDSGFLDTTASLAVSLIGDDSLMQVHPSGIRHIREDGRINEWRTPGKK
MITKVGYNRLQAVIALSGGELLYFEVDMTGQLMEVEKHEMPGDIACLDIAPIPDGRKRSR
FLAVGSYDNCIRILSLDPDDCLQVLSLQSVYSPPESLLFLEIQASTGGEDGADHPANLFL
NAGLQNGVLFRTVVDMVTGQLSDSRSRFLGLRAPKLFAVNVRGRRAMLCLSSRTWIGYMY
QGNFFLTPLTHGILEFAATFSSDNCAEGIVAVAAEALTVFTIDKLGETFDQTVFPLRYTP
RKFVLQPKRKLLVILESDQRAFKAEEREAAQNECFQTGMDDNGNLRMEYVDDNEFSDEQY
GYPKAEVQQWVSCIRVLDPRTGESISCLELEDNEAALSICNVTFNDKECGTLLAVGTAKS
LQFFPKKSFDAAYIHIYRFVDGGKLELLHKTQVDGVPLALSQFQGRLLAGIGTVLRLYDL
GKKRLLRKCENKLFPSTIISLHTYRDRIYVGDIQEALTLLYLNSMSLNS
>Sgl57953 E3_adaptor/Cullin_RING/DCX/DWD 23.6 1.0
MYLYNLTLEKPTGIVTAINGNFSGSSKQEIVVGRGKVLDLISPDENGKLQTLVSVEIFGA
IRSLSQFRFTGSSKDYIVVGSDSGRIVILDYNKVTNSFDKIHQETFGKSGCRRIVPGQYL
GVDPKGRAVMISACEKQNLFYWFICGSSSKHLTFYELDLGLNHVSRKWSEPIDNGANMLI
TVPGGGDGPSGVLVCAENFLIYKNQGCSDVRVLIPRREDLPAERGVIIVSVARHKSLSFI
LVQTEYGDIFKVTLEHGEEGVSELKIKYFDTIPVTSSMCVLKPGDEPDVESSSATMMDLE
TDEGFRPVFFKPRKLKNLIRVDQVQSLMPIIDMKVYNLFEEETPQIFALCGQGPRSSLRI
LRPGLGVSEMATSPLPGVPNGIWTVKRNVKDEFDAYIVVSFASATLVLSIGETVEEVSDS
GFLDTTASLAVSLIGDDSLMQVHPSGIRHIREDGRINEWRTPGKKMITKVGYNRLQAVIA
LSGGELLYFEVDMTDGRKRSRFLAVGSYDNCIRILSLDPDDCLQVLSLQSVYSPPESLLF
LEIQASTGGEDGADHPANLFLNAGLQNGVLFRTVVDMVTGQLSDSRSRFLGLRAPKLFAV
NVRGRRAMLCLSSRTWIGYMYQGNFFLTPLTHGILEFAATFSSDNCAEGIVAVAAEALTV
FTIDKLGETFDQTVFPLRYTPRKFVLQPKRKLLVIVESDQRAFKAEEREAAQNECFQAGM
DDNGNLRMEYVDDNEFSDEQYGYPKAEVQQWVSCIRVLDPRTGESISCLELEDNEAALSI
YGVPLALSQFQGRLLAGIGTVLRLYDLGKKRLLRKCENKLFPSTIISLHTYRDRIYVGDI
QESFHYCKYRRDENQIYVFADDFYPRWLTASQHVDFDTMAGADKFGNVFFVRLPQDVSDD
IEEDPTGGKIKWEQCKLNGAPNKLEEIVQFHVGDIVSSLQKASLTPGGVECVLYGTVMGS
LGAFLPFSSRDDVDFFSHLEMHMRQEHPPLCGRDHMAYRSAYFPVKDVIDGDLCEQFPTL
PVELQKKIAEELDRSPAEILKKLEEIRNKII
>Sgl57982 DUB/USP 239.2 2.1
MTMMTQPALDQEDEEMLVPHSDVVVEGPQPMEAVAQADANSVADNQAVEEPPTSKFTWTI
EGFSKLNVKKHYSDVFVVGGYKWRILIFPKGNNVDYLSMYLDVADAPALPYGWSRYAAFS
LLVVNQAQHKYSIRKETQHQFNARESDWGFTSFMSLSDVYDPSRGYLLNDTLIIEAEVAV
RRVMDYWSYDSKKETGFVGLKNQGATCYMNSLLQTLYHIPYFRKAVYHMPTTENDNPTNS
IPLALQSLFYKLQYNDTSVSTKELTKSFGWDTYDSFMQHDVQELNRVLSEKLEDKMKGTV
VEGTIQKLFEGHHMNYIECVNVDYKSTRKESFYDLQLDVKGCRDVYASFDKYVEVERLEG
DNKYHAENHGLQDAKKGVLFLDFPPVLQLQLKRFEYDFMRDTMVKINDRYEFPLQLDLDR
ENGKYLAPGADRSVRNLYTLHSVLVHSGGVHGGHYYAFIRPTLTDQWFKFDDERVTKEDV
KRALEEQYGGEEELPQTNPGFNNAPFKFTKYSNAYMLVYIRESDKDKVVCNVDEKDIAEH
LRTRLKKEQEEKEDKRRYKAQAHLYTIIKVARDDDLVEQIGRDIYFDLVDHDKVRSFRVQ
KQMTFNVFKEEVAKEFGIPVQFQRYWIWAKRQNHTYRPNRPLTPAEEAQTVGQLREASNK
MHSAELKLFLEIEIGLDLHPIAPPDKTKEEILLFFKLYDPEKEELRYVGRIFVKSAGKPS
EILSKLNELAGFAVDEEIELYEEIKFEPCVMCEHLDKRVSFKLSQLEDGDIICFQKVPSA
DSEERYRYPDVPSFLEYVHNRQVVHFRSLERPKEDDFSLELSKINTYDEVVERVAQRLGL
DDPSKIRLTSHNCYSQQPKPQPIKYRGVDHLSDMLIHYNQNKKDEWTCKSSDILYYEVLD
IPLPELQGLKNLKVAFHPATKDEVAIHNIRLPKQSTVGDVIDELKTKVELSHPDVELRLL
EVFYHKIYKIFPSSEKIENINDQYWTLRAEEVPEEEKNLELNDRLIHVYHFTKDTTQNQL
QVQNFGEPFFLVIREGETLAEIKVRIQKRLHVPDDEFSKWKFAFMSLGRPEYLDDSDIVS
SRFQRRDVYGAWEQYLGMEHTDTTPKRAYSANQNRHTFEKPVKIYN
>Sgl58008 UBD/Alpha-Helix/UBA 29.2 0.1
MRPNIVSEASVTTRLNQWWEGIPFITSAVVAVCAAIYLVCLLFGYDSFVEICFLPSAIVS
QFQVYRIYTSILFHGSFLHVFFNMLALVPMGSELERIMGSVRLLYTTLLLALSNAVFHLS
IAFMVAHNPFHPYPYLMAECAIGFSGVLFSMIVIQTSLSGAQSQSVFGLFNVPTKWYPWI
LLVVFQLLMTNVSLLGHLCGILSGFAYTYGLFNLIIPGTSFFSGIESSSWLSACVRRPKF
ILCTGGNPSGYIPTYTNPNSTSSGSVTNLWSHLTSLMPQRDTSSQNVQSTQDNRFPGRGR
TLAAPRSETAPSVTPDSNLQTRLLDDTGSNEQSDMRAINSGGGRSPAVNSATEPTSSPQQ
QALVVSAEDSQRLVAMGFDKTQVEVALAAADGDLDVAVEILMTQQV
>Sgl58201 UBD/UBC-like/UBD_UBC 66.6 0.0
MSLDEEDEEEQIESSSEEECTPETESDNDRDERTLVLRRNLHTQSSSNKEKRENIFHTRC
KIGKKTCTLIIDGGSCTNAIFEKTVNRLQIETARHPKPYKLKWLDDDSEVQVRRQAVVNF
TIGSYQDEVLCDVVPMDAWENEKTLLPLPPSKVAEKMEKTKAQEVLIVSRKQVTKTLQET
RAIWILLTKELADEGIKLISNINNPALQQLVRKYEDVFPAELPPGLPPLRGIEHQIDLIP
GASELAADLKQAKPKFDAAGVELIAVGVGTADKARLLGERNVKADSEKIQKSMNLEHEPV
EKVKKSLPRAYSRIDSEKDLTSQMGLSPYKGGAWKIMVELPNAYPYKSPSIGFVNKIFHP
NVDEMSASVCLYVINQTWIPMFDLVKVFDVFLPQLLLYPNSSDPLNGEAAALMMRDKVAY
EQRVKGSGVTAQWLKFDNSYFKVLHLLPLNPKVYSFSNLA
>Sgl58376 ULD/UDP/UBQ/UBQ_Other 23.8 0.0
MVMIRVRSRDGVERLSIDNPNTTTISQLKTLIESQLHVPISNQTLSLNQNLLLAKTPSDR
SQFCDMANPQTLISSLNITHGSLIFMYYDGEREIVAPSRRPTITPAGSFGKKMTMDDLIA
KQMRVTRQESPNCALVSFDRDAANAFQHYVNETLAFGVKRGGIMYGTVSEDGRVEVDFIY
EPPQAGQEERLVLMRNKDEEKIVDAIANGLGMRKVGFIFTQAVGQDKKDYTMSSLEVAQA
IELHAESELKEWVTALVKLKVNEDGGADVHFEAFQMSDMSVRLFKEGWFDFECKEGEEID
PKVSRMKKDVVVGGKDVREVDNDFFLVVVKIFDHQGPLSSTFPIENRMVPVTTKAVKTHL
ERTKSLPFVKRISDFHLLLTLGRFFDLNADIPALTECVHSQSSVPEGYQLLIESIANAGV
>Sgl58403 UBD/UBC-like/UBD_UEV 173 0.1
MAPLQPHSQSQSIHSNPQILQFLSNVLSQRGPSSLPYSEDVKWLIRQHLVSLTDAFPSLQ
PKTATFTHNDGRTVNLLQADGTVPMSYGGVTYNIPVVIWLMELYPRHPPCVFVNPTRDMI
IKRPHPHVSPSGLVSIPCLHKWVYPSSNLVDLARDLSVFFGRDPPLYSQRKPDSPSNNPN
PNPTVSTYSNHSHSHSFGGDSSNSASSGSIGHPPRVFPPSPYVGSGRIMPQRPSGGTDDP
NEVFKRNAINKLVEMVHGDVVGLRKTREADMEGMFSAQATLRQREEKISNGLKNMLDEKE
GLEQQLQLVLTNADVLEAWLKENEEKMSKLGDNVDVDDAFEPCDSLSKQIIEASASDLAI
EDVIYALDKAVQDGVIPFDQYLKNVRLLAREQFFHRATSMKVRAAQMQAYVASMASRTAQ
HMM
>Sgl58595 E3_activity/RING/RING 19 4.5
MECLHRFCRECIDKSMRMGNNECPACRTHCASRRSLRDDQRFDQLIAVLYPDIRKFEEEV
MYELEDVDLQKICYEVPPKRKKKEVAFYDEDEARNKQIKESITQVLIKQSEALGKKRSSN
KDAVGPSVTRSQR
>Sgl58621 E3_activity/RING/RING 35.7 6.5
MNKYPLITFTLLYICFLLPQLKAVELCSSFSCNRHRHDPIMFPFRVPDNQSTRCGYPGFE
LSCNNSNDQTLLSLSSEPLVVEAIQYMYQLILLSDPNHCIPKRVMDLGLQPTPYSFGRRA
SPYTFLNCSKTNNNVTLVDDLPKGSSVISCMSDGNDTVVATFNNRAEEEMVGRRGCTVMK
RLNAAFWWRDMEYGYEEVDLSDALVELSWGVPDCRECYGRGGSCGLVGGSGLEVGCLLPD
SSDFPKGAKYGLILGAGIPALLCIIGLIIYIGSRIRIARNRHHHHTNTGSSPSIFPQPIV
LTLGLDQPTIESYPKTVLGESKRLPKPSDNTCPICLSEYQPKESLRTIPECKHYFHADCI
DEWLRMNATCPLCRNSPDRSSTLPNC
>Sgl58997 UBD/UBC-like/UBD_UBC 177.6 0.0
MVDFARVQKELKECNKEMNVSGISVKIKDDSLSHLIGTIPGPVDSPYEGGSFLIDIVLTD
GYPFEPPKMKFLTKVWHPNISSQSGAICLDILKDQWSPALTLKTALVSIQALLSAPEPDD
PQDAVVAKQYLKEYQTFVGTARHWTEAFAKTSSHGIEEKVQRLVEMGFPEAQVRSALEVV
GGDENLALEKLCSS
>Sgl59010 ULD/UDP/UBQ/UBQ_Other 40.9 0.0
MPEEDLVDIKFRVYDGSDIGPFRYSSASTIEMLKERIVSEWPKGKTVVPKAATEIKLIYF
GKVLENNKTVGQSRAPFGELTGGVMVMHVVVQPSQAKTKSEKKIEESKKFVCSCCIM
>Sgl59043 E3_adaptor/Cullin_RING/DCX/DWD 109.3 33.4
MAPIFEYFIVCGIGAEIRTLDEYKGFYGTNYRYLPSLLDQYPPSNQSPSPPPPPQLPTCV
LPAGVEFYASGFDRNDPSTYPRTYPIVLTEGDGSKIYVTCIAFRDPVDEDIVDAHHIPLN
SLADKCICLVSRLPSFHVLRYALEEIFALCFSPSGSCKPLWDVIAYMVSNVPLPTPGKDR
VLFAIENSLLCVEAPPKDGLPHADISFQPLVQCLDVDNLLKLFTAVLLERRILLRSNKYS
LLTLVSEAICHLIYPFRWQHVYIPLLFFSGVDYIDAPTPYMMGLHSGVDTTGLSMDGVVI
VDLESNRITTSEEIPPIPEPELSSLRGDILKLLYPNVVDIDLMKSGLRKSFDLYHRVANR
PWSEEHDAQLRMIFLKFLASILSGYRNFIENSATNIFNTQAFLKKRSRLTNQPQDEMIFQ
FLETQGFLDFLERGLGSDYNNSNLLDKLQDAIGRGQDYMSILPSPVLDPEIITISDLGGG
IPASGARYTYERFPSNIRTEEQEEKRKQILAAVSGAQDNPAKATLDHAESLSPRERAAER
ERMVLDIKVKLQGLWLRLLKLGTTDDPLSSFEYGTILALIESDADGVGGSGFVECIREHI
HTGWTCQLTEEQFIAVKELLKTAINLATSRNDMSTVRDALEVSAEIYKKDSNNVSDCVQR
HLISLSIWEELRFWEGYFEYLMDQTSNKPSNYATLVMTQLVVVASHMAGLGLPDTDAWLI
IETIAEKNNIGYKQFIQLRGFLSHIHQLRYAYWGIAASKVQSLSSYGVQSALPQDGVHDS
QQTTEASSGRSWVQSMFSRDSSLRAQSFTRVRSGLSASDENKQDLANATGQKRPQTNVRI
LRGHNGAVTALHCVTRKEVWDLVGDREDAGFFISGSTDCLVKIWDPSLRGSELRATLQGH
TGTVRAISSDRGKIVSGSDDQVILVWDKQTYQLREELKGHTAPISSVRMLSGERVLTSSH
DGTLKMWDVRTDACVATVGRCSSAILCMDYDDSTGVLAAAGRDSVAYLWDIRAGRQIHKL
LGHTKWIRSIRMVGDTLITGSDDWTARMWSVSRGTCDAVLACHAGPVQCVEYSPLEKGII
SGSTDGMLRFWENTDGGIRCVKNVTIHSAPILSINAGEHWLGIGAADNSMSLFQRPQERL
GGLSSSGSKVTGWQLYRTPQKSSAVVRCVASDLERKRVCSGGRNGFLRLWDVTINI
>Sgl59048 E3_adaptor/Cullin_RING/DCX/DWD 111.6 25.9
MARLFDYFVVCGIGPEIRSLDGRSGYFGMDLAYEASLIDQYPPLSHSSYAPLPPELPMCV
MPAGVEFQRSGFEANDPSSYPRSYPIVLTAGDGAKIYVSCIAFRDPVDEDISEAYGIPLN
SFAGKCISLVSRIPCFCVLRDALEEIFALCFSARGSCKPIWEVITATISNVPLPTPGIDR
VLFSIDNCLFSAEAPPENGLPHADISFEPLVQCLDAHNIIFLFTALLLERRILLRSDKYT
LLTLVSEAICHLIYPFQWQNVYIPILFSKGVDYVDAPTPYIIGLHSSVDTSGLSMDGVII
VDIDHNCISTSEEIPPVPEPELSLIHGEIRKLLYPNVMHIDDVYSGIGELYMRCPKDAVK
PWGKDHDLQLRLIFLKFFASTLSGYRNFIVDNAEYSFDAQAFLIHRCRSNNQEPDSMITE
FLASQGLSNYIERIVSSGESNDNVLDKLIDAIGRGESAMSVIPSPHTDLNIVTIPDPTDG
ILDSHAKYMYVKFPANMRSEEDEEKRKQILQYIKDKDDEEKGMIMDIKVKLQGLWTSLLK
LGDAEIILSSDEYETILALVETDAKGIVGRTLIECIREHMRAGWNGQLSMEQFIAVKELI
KGLITCATYQNDIPTLRDALEISAEMYKKDFNDVADYMQRHLLSLPIWEDLGFWEAFFES
LMDQSSLKPSSNERFIMSQLIMMASHMGGLGMPDADAWPIMQDIAQKNNVSYEHYIQLRG
FFSYIYQLQMVYWGISDLKAQSMSSITQSPHFEDAIVDSQQPAKPSTVAKNWVRNMFGRE
SVLKPNSFYRARGWAFDTETTAANEIGTPRKQRKVQTNVRVLRGHRSAITALHCITRRDG
WDVVGDREDMGFFISGSTDCSVKIWDPSHRGSELRATLRGHTGAVRAISSDQRKVVSGSD
DLSIVVWDKHEFLPLEELKGHEAQISYVRMLSGERVLSSAHDGKVKMWDARNGSCIATVA
RCPGAVLCTEYDDTTGILAAAGRDSVVHIWDIRAGKLMHKLSGHKKWIRSIRMAGDTVIT
GSNDWTARLWSISRGSCDAILASHGGSVLAVEYSSLDGGIITGSDDGSVRFWDNTAYNIK
CDKDMKLNSPILSINAEQQWLGVGAADNSMLLFHQSREDTSGRWQLYRTPQFSATTVRCV
ASDLERKRICSGGRDGRLRLWDATVNI
>Sgl59153 E3_activity/RING/RING 26.4 8.7
MTSVTAFSDEHLTNNLIIPDQGEMEEVIEKGVEMGALVNDGVCAICLDDIELQETALIKG
CEHAYCVNCILQWATYHEHPRCPQCKHPFESLGLHRGLDGSLHDYMLEESVCLLLRASWF
KPLDVEHQPGFYDDPDDIFYYQYQQYHQYEYEDMDEDLEDSFFHNSTSLRIGNRRWGDNG
YVRAGRQEARPVHRSNPQNSGGSSSRQRKKKEVEKDPESASSSDSPNKKEAGKDLVGRRA
KRALKREAADKAAAVKHQQHLVRLGLY
>Sgl59177 E3_activity/RING/PHD 37.8 34.9
MDVNACVGLGVELRSGDASGVVDANHVNNSVCEAQLEGVGPEAATPDQCQDGTLGQRKRR
KFGRNLKSSAETVLRRSARRAKVVAADENNGSSAILVDDPNDLSMSGVIDEIEEKSLRKK
LETPVEPQVPPKIELPPSSATLNLEGIPVLDLFCVYSCLRSFSTILYLSPFKLEDFVAAL
TSRVSNQLLDIIHVSILLTLRKHLDFLASEGCESASTCLRNLNWDLLDVITWPVFMVEYL
LLHSSGLKPGFTFSHLKLFDGEYYKQPAEVKLDLLRCLCDDVVEVDAIRSELTKRKIIAE
ANMEASRTMCSGRKRKTSIEAPGDSCLSEDVNEELADGNSDECCLCKMDGNLICCDGCPA
AYHSKCVGIVSSLLPEGDWFCPECVIGRLNKKSVQGAELLGTDPYGRLFFSCFNYLLVSD
SNDAEALCSYYHKDDLGAVIQLLQSFSIHYGSISSAISQHWALTDSCQPKSDVESKPCIE
TDNLLTTSEGFGEVLQENGSTKSGKPVSDIVAGGAASKQRKKKGSARRGRPSLKAKEEDV
FQGQSGDNYINCYNFALTASSVVEELLRKPSGKVSIDAPKTEEEIISIQLKFILNKSSKP
CWTAIQELNRERQKEDCGWCYCCRFPVEGRGCLFSVQNSSPIPDALKVEIEGILCKKNKK
GHLADVICYIISMEERLRGFLVGPWLRPQYSELWRKRVLKASDVLSLKAPLLLLESNLRP
LALSADWLKHVDLVTTMGSATHFVASSRATSKNGISRKKVRGGESKSKSSTAGLVYFWWR
GGKTSRSLFNWKGIPHSVAMKVARKAGCMKIPEIQYSDASENARRTKCFAWRAGVETSTS
IEQLALQVREFDLFIRWNDIENTHPHSLLDKGSIKSIRLFKKVIIRRKRLEGTVAQYLLD
FGKRRNVPDVVLKHGQKFEESDSERKKYWLNEEYVPLYLLKSFEERRISRKVGKTNSSKL
WKDGKVIKKPLREKGFDYLFSRAERVDSHQCGHCNKNVPISDAVSCQLCNGYFHKRHVMK
FSEGITTGCTYTCHRCRAGKHVKKESNLGKRKLSKLRDPKLLKVAIEGHSATLRAKPKKR
GRPSAASKRQVILRNAKKMPCHEQTSLQKNADVSIGINLRRSARKANCTTTYFSKFAKGT
VHSNKISKGTLHSTKIGKGKKRKTNKRRKVETKEIPKSFSWKKKRTDVLHSFWINGLLLS
MKSNDERVIRFKRRKLLAPSEFFTENDDQLKCSLCSRKGSTSTMMYIACEICGDWYHGDA
FGLNKGNVESLIGFKCHICRERSPPVCPFVDISRDNSFLNESEACHAEESPSAVVHKEAN
RVQELQCNEGPVLLEDHTAQNCVGTLDQDETAMLDSELIVENESNTCKDVASCSVESQNA
NLGPNLPKESDGNNISEGPDFLEVHTPQICDETLDQDESLMLNSELRVENEALTCEEGAS
CLVESQDVNLAAKVLKVSDDNSILEGPSGFLEANTAHNCDGTLAQDESLLLGSALRVGKK
SLICEEVASCSVESHVNLGAKLPKESDNNIISEGPGFLEVHAAQICDVTFNQNDTAMLES
ELSVGNGSFTCKEIASCPVEGQDVNLGTELPKESDGNSVPEGPSGVLEDHEAQSCDGTEL
RAENESLTCKEVASCSVESPDVNLQAKVLKESDDNSIVDGNQIN
>Sgl59182 UBD/UBC-like/UBD_UBC 133.3 0.0
MTMNGGYSDNTPATTPAAVPAKQNVAPAKTVDTQSVLKRLQSELMSLMMSGDPLISAFPE
EDNIFSWKGTIHGSKDTVFEGTEYKLSLNFPADYPFKPPKVKFETGCFHPNVDVFGNICL
DILQDKWSSAYDVSTILLSIQSLLGEPNTSSPLNTQAATLWSNQEEYRKMVEKLYKQPTT
A
>Sgl59201 E3_adaptor/Cullin_RING/SCF/F-box 20.6 0.0
MEEGEEESPQKVINFNNLPKDIIFDILSRIPLKTLCQFRIVCKKWQFYLCLNPEFRLFYH
QKHKINPILLFNHLIPENHSTQFSSYFIDGTPLTQISTNFAQPLNSILTCNGILCLISEK
SVYFYDPITKLHSQLPNSTRFDSTLSWAFGFSRVRNVFILLHFYTIEKFDNFHYCPLKEK
MCEILTTPISDLWVEESHEEWRDLGYCPFEFLSLKNNFAFVDGKFYWLMREKGFNPIKIM
SFDLETEVFGMFYFSQTNVSVECLDLVEIKERLCMTDRLPWSSTMNVWMMKKEDDGVDDL
WVKKYMIDLKGINHHDVRIFGHFPRVNNGDYEDEILMKIGKSFGFYEIESGVFKDMATET
NMEKWGLELLLNRKSLL
>Sgl59254 E3_activity/RING/RING 37.3 5.1
MASDSSIAEHLKWRKPKIHNHPKHSTTPSSDPNPQMPSIIQSTGCKSTISSLLLSTFTNN
ENPHNSKNKPPRKSSSLRALGCASSQPQVTVPNVIRSSAVWEENNKDKKKNKKKKNKNKK
KMMMINQQQLQGVLMDEQIGVQDLWCADSSAANDSVDCVRPRSARGKIDLDKLHQRERAS
YTSRQRVNNEQFSGLEMDSAFDVPSFGPDVFEARYYNNLRNRSPEGLAEILMFQNGILSN
RRSGADKYRDLRLDVDNMSYEELLELGDRIGHVSTGLGEDQIGRCLRKTKLSVLHELPPH
PHMSSGIEGKCSICQEEYEAEDEVAKLECEHAYHLHCIEQWLVRKNACPVCKAEASSP
>Sgl59303 E3_adaptor/Cullin_RING/DCX/DWD 151.2 21.5
MGEQLQLRGTMRAHTDMVTAIATPIDNSDMIVTASRDKSIILWKLTKEDKTYGVPSRRLT
GHSHFVEDVVLSSDGQFALSGSWDGELRLWDLAAGTTARRFVGHTKDVLSVAFSIDNRQI
VSASRDRTIKLWNTLGECKYTIQEGDGHTDWVSCVRFSPNNLQPTIVSSSWDKTVKIWNL
TNCKLRSTLAGHSGYVNTVAVSPDGSLCASGGKDGVILLWDLAEGKKLYSLDAGTIIHSL
CFSPNRYWLCAATESGIKIWDLESKSIVEDLKVDLKTEADHLEGATTTASKKKVIYCTSL
SWSADGQTLFSGYTDGVIRVYGIARY
>Sgl59339 UBD/Alpha-Helix/UIM 12.9 0.6
MESSCNGGLLYHEVQESKLCAVHCVNTVLQGPFFSEFDLAALAADLDGKERQMMMENRAS
VGDFRSDESHNVSLGGDFSIQVLQKALEVWDLQVIPLNSPVAEPAQIDPELESAFICHLQ
DHWFSIRKVNGEWYNFDSLYAAPEHLSKFYLSAYLDSLKGAGWSIFLVRGNFPTECTLPS
SEASNGYGQWLTPEDCVRILKSCNSKGESSLAIDRTPNQPTDQFASLSEAELLAMEDEDL
KAAIAASLQDSAPAIPVLESGAPSTEKSS
>Sgl59396 E3_activity/RING/RING 30.5 5.6
MNSTGSTYWCHRCDRFIRVHTQHIAICSDCGGGFVEAIDGSSISPLSPISSTTPTRLVPT
NFEDSRSISTSSSPSFNPVIALSRSPEGISFPNYQLFYDDVNDNGIDNDDESRLGFRPLP
VNVAEFVMGSGFDQVLSQLGQLDLNGGFSGLDNSPASKAAVESIPFVEIVDAHVDCDSHC
CAVCKEQFEVGTEARELPCKHIYHSDCILPWLLLNNSCPVCRFKLPTDSGNGNGSGNGNR
DLNSEGISIWRLPGGGFAVGRFMGGGRRNAEEGLFPVVYTEMDHNHNGFENIGDLRRISW
PSRGRRSGRRRGWGRAFRSFFGLFNRNRSSSSRLSVEVEASVSHSRFRMGV
>Sgl59434 E3_adaptor/Cullin_RING/DCX/DWD 103.8 9.0
MDLKRKMTMNWDGLLDEDDDFFDTTNRISAVVPMDMLACPYDDSSDEDEFEDPRMSFTSV
SSFKNGGHTRPTTTANVCGPTPPMPAPKSSSSNEEYDIWMAAPTSIEDRRRRLLHGMGLN
SSKELMRIQTMVMSKKFAAASETSLSSHPLPATSNREDQEHPCETTSPDTKGTDDHNDHD
HSTTTTSSTPSPDSSVYLIRSRSDGDIEPFSMETRRRKEHLIGDVSKQRLTRTLSTLAPF
TRVCKMSYNDGNSCTTSGTTTATTTTTTSCNDKSHDEKNVGSNKECNDNVCKNNDNCNNK
KSAKNGKKGKSNQQKSGEQLGAFFLIKNLDTGKEFVVKEFAEDGMWNRLSEVQTGKQLTL
EEFEKSVGYSPVVKELMRRQNQRRSNSIDSGGAPLTLERKTSVNAYLSKSFRNSKRRGVS
LLKNINKVANSVTGLGGSTPEREPHSVAQAQTQTQTQTQAQTQTQTQNQAPTPVEQPKGG
KSGASGNNNDWVRVRTQGKAYKELTALRFCQEIQAHQGSIWTIKFNFDGRYLASAGEDKV
IHIWEVQECEIASLKPPEECANSTPVHPMFCPSPDRDTPAIDKKKKGRSGSRRGSIMPDY
VQLPETVFALSNEPVCTFQGHLDDVLDLSWSRSQLYLLSSSMDKTVRLWDLETKTCLKLF
AHNDYVTCIQFNPINDEYFISGSLDAKVRIWSVPGRRVVDWTDLHEMVTAACYTPDGQGA
AVGSHKGNCRMYTITDGKLNQTIQFDIQNKKKTAPKKITGFEFASDNPNEVLVTSADSRI
RIYDGSEVTQKFRGFRNTSSQISASFSPDGKYVICGSEDSNVYVWKREEPRNNGKTKTLI
DTRSYEHFQCKDVSVAIPWPGSIKFDPPTIQLHAKKNTKKPAATSSSSATNSPRKDEVNK
NNKRQHLPPLPNNKKNTNVTDKSNNKDNNNNNESQTNVNNNKDEENDKSNISNNNNTNEG
NLEGEKAPESPEADPAQISRTDSGIGDSFSSSAGASLRYDDSPSITSNHASSPSWAPGWS
WFDGGASHGSDTMQARAWGLVIVTAGLGGEIKAYQNIGLPLKVGRQSNLFLA
>Sgl59450 E3_adaptor/Cullin_RING/DCX/DWD 88.5 6.7
MRPILMKGHERPLTFLKYNRDGDLLFSCAKDHNPTVWFADNGERLGTFRGHNGAVWSCDV
SWDSSRLLTGSADTTVKLWDVKKGEQLFTFNFDSPARSVDFSVGDKLAVMTTDPFMEKTS
AIHIKHIAEDIEDQDKESALVIRGPTGRINRAVWGPLNETIISCGEDAIIRVWDPVTGQE
IMSTKDNKSGHKQAITSLSMSADKAQFLTGALDKSAKLWDTRTLTLIKTYVTERPVNAVT
MSPLLDHVVLGGGQEASSVTTSDPRAGKFEAKFYDKILEEEIGSVKGHFGPINALAFNPD
GRSFASGGEDGYVRLHHFDTDYFNIKL
>Sgl59534 E3_adaptor/Cullin_RING/DCX/DWD 17.4 0.7
MKNCQSKFFRGEAKSGNDGAGVGAILSLGVLPPSKAVEILKLYSCFYKGVQSAAIDVCGV
SYMNQCTVPFDASFVSSLIPSSSPIVSAFSSSDDSILVAHSGQISLYHPLTLAFQSSFRT
HAPQVLVTAAVADSGPVFSAAYNSHHGENALLLIDKETLKVVSEIARQSGNSAKSSSITK
IRWVPHTRLLVGSSVNSGAFGYSAYVRVWDPRSGEMVWETNEPGTNTTRGTCFLGEMPTW
KLGQQWRRTHTIGLGLCKQVSWSRFGKRENYWGATTLLVLVYTKQVLVES
>Sgl59587 E3_adaptor/Cullin_RING/SCF/F-box 18.4 0.0
MEALPPELIEKILSRLPAESLLCLKTVCKSWNSIIKNPEFIKLHLNETLISNSHRRLLKS
SMDLKKRKLSFYSAELDSDTRTHTRTDRRRLSYSMLNHPLKFNYATLFGSCNGVVSICDF
TSRPNILLLYNPFTKSRRILPMEGLPCFNSNSEWINLLYGFGYDSKTEDYKVLRIVQRYR
FYEGDHVCSVYSLNRSCWKSVNGTVLNRCSFSHNCVHGVLVNETLHYLVNDRKMMIVCFD
LGTESSSLMDCPNHDDENNNNLMMITRCKSYLAELDGCLCVMVMYFTQNYNAVRADLLVM
KEYGNKESWSKVFSVSVDQLTSVCVCFRRIKPITYSKDRRRILIDIDDGFVTGWFDLEAK
KFKKHRHRGLPVRHFDTSSFMGSLVSFTRT
>Sgl59593 E3_adaptor/Cullin_RING/BCR/BTB 26.5 0.0
MRTFFHSESCKEPHLNVLNPQSWLQVERGKVSKVAAQASSSIGSLIKVPEPPIVPHFKPV
DYVQVLAQIHEEFESCPPNERSSLYLIQFQVFRGLGEVKLMRRSLRNAWLKASSVHEKII
FGSWLKYEKKGEEFIFDLLGSCSKCAKEFGPIDVASELQDDCSSPLSENASISGSEGIET
VFFRIGSERVRCDRQKMACLSAPFSAMLNGCFTESLCQEIDFSENNISAIGMRAISDFSR
NGCLDDLSPELLVELLVFANKFCCENLKDACDRKLASLVSCRQDAVDLLECAIEENSPIL
AASCLQVFLHDLPDCLNDERVVEILGNANGEQLSVVVGQAAFSLFCLLSEVSMSLDASSD
TTVLFLERLVQSAKNNRQNMIAFHQLGCVRFLRKEFDEAEQLFQKAVREGHTYSIAGLAR
ICYNKNQKSVAFEKLNALILTSSPLGWMYQERSLYYEGDKRWDDLEKATELDPTLTYPYM
YRAASLMRREEAEAAIAEINRILGFKLALECLELRFCFYLALENYEAAFCDVQAILTLSP
GYQMFEGRVAATKLRMLVREHVEKWTTADCWLKLYDRWSSVDDIGSLSVIYQMLESDAAK
GVLYFRQSLLLLRLNCPEAAMRSLQLARQHASSEDEQLVYEGWILYDTGHCEEGLCKAEE
SIKLKRSFEAFFLKAYALADSSQDPSCSSAVISLLEDALKCPSDRLRKGQALNNLGSVYV
DCGKFDLAADCYVNALKIRHTRAHQGLARVHFLRNDKTAAYEEMTKLIEKAQNNASAYEK
RSEYCDRELTKADLEMVTRLDPLRVYPYRYRAAVLMDSHKEKEAIEELSRAIAFKADVHL
LHLRAAFHEHIGDVMGALRDCRAALSVDPNHQEMLELHSRVNSHEP
>Sgl59610 E3_adaptor/Cullin_RING/DCX/DWD 35 14.9
MFQGTNKKTMKWTTLLKDLKEKVGLTQQQQSSSSSSLASSSAFPSSSAPSLSSLAVLRGD
YNDAPYSTPDYHRTYLNNTRDKHELEMDFKRFWEDFRSSSSEKEKEAALNMAVDAFCKLA
KQYADIAQLVTMLVEMHIFSFVVGRAFVTDIEKLKISNKMRSLVVEEVLRFFSEVTKDGI
CPGANLLSAIELLIAGAVDKQSLLDSGILCCLIHLLNSLLGSNGGNVGNTDSDHDRQLEC
NHMAEAGGLRARQLEVEGSVVHVMKALASHPCAAQSLIEDDSLQLLFQMVVNGSLHVYMQ
YRDGLVPLHSFQLHRHAMQILGLLLVNDNGSTAKYIRKHQLIKALLMAIKDFNPDFGDPS
YTIGIVDLLLECIELSHRPEAGGVKLREDIHNAHGYHFLVQFALTLASMSQKQTDRALHS
NSFSEESATGDSRAIGNSGNEESIDSEDGKTSNLSPALSRLLDVLVNLAQIGPAEPPAPR
SSKSSHVKGGGHGRSRTPSVDLSTDEIWEKGNGKVKDLEAVQMLQDIFLKAGCTELQAEV
LNRMFKIFSSHIENYKLCQQLRTVPLFILNMAGFPSALQDIILKILEYAVTVVNCIPEQE
LLSLCCLLQQPITSDLKHTILSFFVKLLSFDQQYKKVLREVGVLEVLLDDLKHNKFQSGP
DHQNSETNHLERKSSPTGFQKHMNSKDAIITSPKLMDSGSGKYLLFEVEVTVSIAWDCMV
SLLKKAETNQSSFRSANGVAIVLPLLVSDVHRSGVLRALSCLIMEDVTQVHAEELGVLVE
VMKSGMLTSVSGSQYKLHDDAKCDIFGALWRVLGVNSSAQRVFGEATGFSLLLTTLHSFQ
SDGEQTDHSHLIVYVKVLTYLLRVVTAAVCDNPVNRTKLHVIVSSHTFYDLLCESGLLCV
DFERQVVHLLLELALEIVISPFLASGSATSSEKVDSSSFLLTTPSGVVNPTMERVYNAGA
IRVVLRSLLLFTPKVQLEVLELIEKLAHAGPFNQENLTSVGCVELLLEMIHPFLQGSSPL
LMHALRIVEVLGAYRLSTSELRLLVRYVTQLRKKNSSESLVGMMERLILMEDMASESVSL
APFVEMDMSKVGHSCVQVSLGERSWPPVAGYSFVCWFQYQNFLKSPAKESEHSKVGSKKL
SSSGQQQQVLRLFSVGSVDSGNTFYAELFLQEDGVLKLATSNSSSLSFSGSDLEEGRWHH
LAVVHSKPNALTGLFQASIAYVYINGKLRYTGKLGYSPSPVGKPLQITIGTPASHARVSE
LQWKLRSCYLFEEVLSSGCICFMYILGRGYRGLFQDTDLLRFVPNQACGGDCMSILDSLE
ADVNSVSGTQKPDSSVKTGISRTDGSGIVWDLERLGNLSLQLSGRKLIFAFDGTSTEPLR
ASGTLSLLNLVDPTSAAASPIGGIPRFGRLHGDVYVCKPCVIGDIIHPIGGMVSVLALVE
AAESRDMLRMALTLLSCALHQNPQNVREMQACRGYHLLSLFLYRRMSLFDMHCLEIFFKI
AACEASFSEPKKLGISHPSLSPASSAPEASFEELSLSKFRDELSSLGSHGDMDDFSAQKD
VFSHISELETADMPSENTNCIVLSNADMVEHVLLDWTLWVTAQVSIQIALLNFLEHLVSI
HWYRYHNLTVLRRINLVQHLLVTLQRGDVEVPVLEKLVVLLGVILEDGFLASELENVVRF
VIMTFDPPQLAHRTAVVRESMGKHVIVRNMLLEMLIDLQVTIRSDELLEQWHRVVSSRII
TYFLDEAVHPSSMRWIMTLLGVCLTSSPTFALKFRTSGGYPGLTRVLPSFYDSPDIYYIL
FCLMFGKPVYPRLPEVRMLDFHALVPSDGDHSEIKFVELMDSIIAMAKSTFDRLSTQSML
AHETGNLSQIGPSLVAELAEENSDMIGELQGEALMHRTYAARLMGGEASAPSAATSILRF
MVDLAKMCPSFANVCRRAEFLENCVDLYFSCVRASYAVKLARELSIKTEEKNIIDFEDTN
SSQNTFSSLPQDQDQSGKTSISGGSFPQGQVSSSSEDIPLAMNGKIVKQEDLSASNKKSE
VTLATQEDIPAVQILDDVTNDKVSMNPSSITDVNVPNVTTMVMSDIPTDTQSSTSIAMPN
SPILSERSGSKLAPTIGPSDVALTSGPHSTTNASFVSSNLTSENDLIVDKKHSPQGSSES
SFFVISSKLLLEIDDSGYGGGPCAAGATAVLDCLAEVLSDVLTEQIKAVPMVERILESVP
LYADTEAVLVFQGLCLSRVMNFLERRLLRDDEENSKKLDKSRWSSNLDVFCGVIVDRIYM
GAFPRPAGVLRTLEFLLSMLQLANKDGRIEEAYSVAKGLLSIGRGTRQLDPYISAILKST
NRMILYCFLPSFLGTIGEDDLLSSLGIPSFNEKEQTSAYQQEETGIDICTVLQLLDAHVR
IVFCPSNVDAELNCCLCVNLISLLHDQRQNARNMAIDILKYLLVHRRASFEDLLVSKSNR
LDVLRGGFDKLLTGSISSFFEWFQSSQPTVNKVLEQGAGLMWVQSITGSSKFPGLRIKSM
DNHRGSEMIKKSKELAKLDVKHWEQITERRYALELVRDAMSTELRVVRQDKYGWVLHAES
EWQTHLQQLIHERGIFPTRKTPEAGESEWELCPIEGPYRMRKKLDRCKLKVDTIQNVLDS
QFDLGQADLSKEKNENGRDASDSGSDSFSQLLVDGGQQLSLEGELYDEFSVKDCDDVREV
SSAREALIDDRASSINESLHSAVEFGTRSSALSGPISDSLQGKSEVESQLMSSSMKTDDI
KVAEDRSERELLDNGEYLIRPYLEPFEKIRFRYNCERVVGLDKHDGIFLIGELCLYIIEN
FYIDSSGCICEKESEDDLSIIDQALGVKKDVMFMDFQSKSTSSWAATVKTGAGGRAWAYN
GGAWGKEKTCSTGTLPHVWRMWKLNSVHEILKRDYQLRPVAVEIFSMDGCNDLLVFHKKE
REEVFKNLVAMNLPRNSMLDTTISGATKQDSNEGSRLFKLVAKSFSKRWQNGEISNFQYL
MHLNTLAGRGYSDLTQYPVFPWVLADYESEDLDLSNPNTFRKLDKPMGCQTPEGEDEFRK
RYESWDDPEVPKFHYGSHYSSAGIVLFYLLRLPPFSTENQKLQGGQFDHADRLFNSIRDT
WSSAAGKGNTSDVKELIPEFFYMPEFIENRFSLDLGEKQSGEKVGDVVLPPWAKGSAREF
IRKHREALECDYISENLHHWIDLIFGFKQRGKAAEDAVNVFYHYTYEGSVDIDSVTDPAM
KASILAQINHFGQTPKQLFVKPHVKRKVDRKPPHPLKHSINLVPHDIRKTSSSITQIVTM
NDRILLAGTNHVLKPRTYAKYIAWGFPDRSLRFMSYDQDKLLSTHENLHGGDQIQCVGVT
HDGQSVVTGADDGLVSVWRIQKDSSQRVRRLQLEKALCGHSAKVSCLYVSQPYMLVVSGS
DDCTVILWDLSSLAFVRQLPEFPSPISAVYVNDLTGDIITAAGVLLAIWSVNGDCLAVIN
TSQLPSDFILSVATSSSSDWQDTNWFVTGHQSGAVKVWKMVHCTDKESAQSKPTANGTAG
LALRKQPEYKLLLHKVLKSHKHPVTALHMTSDLKQLLSGDSAGHLLSWTLSGDSLRGSSS
YG
>Sgl59648 E3_activity/RING/RING 29.3 11.2
MSSDHIIIHQDEELSTSSFIRIIKITPYPVSFGSINKPLERYSVACTIKQTTITVFSSYD
EQPGLLVRAHESHPNKSITVNYVPSSEIELEITRFCLRSRLHLSPENEDALMDMIHHQIK
INNGFNNVRPNSNNNQNQQEQDVWPDQMHLDVTFHQVDIERRYVSLDQLHGFALSLKNEE
CSVCLEELDKNGKTQPLICLCCDHVFHESCIVNWLATSLSCPLCRREVPLEI
>Sgl59650 ULD/UDP/UFD/PB1 70.8 0.0
MARSETYENDLHLEATELRLGLPGSKEPQDVSNNVSKSNKRSSPDQVLEDSSSTNNSSVS
DARNDECPPPSKTQIVGWPPIRSYRKNTLQAKKTESEASGMYVKVSMDGAPYLRKIDLKV
YQSYEELLKALESMFKICIGKYSERDGYNGSDLAPTYEDKDGDWMLVGDVPWEMFTTSCK
RLRVMKSSEAKGLGCL
>Sgl59651 ULD/UDP/UFD/PB1 60.7 0.0
MEVGLKMEDTELSLGLGLGLGLRGGGDKSSDGGGGVVKSNKRGYSETVELKLNNNNNNNN
NNCVAVAKEESATSNPLDLLMKNDNKKNDVSPKEVSSKVVDHAAKPPSKTQVVGWPPVRA
YRKNMLAVQKTTGGQDSESEKLMSGGGGALVKVSMDGAPYLRKVDLKMYKSYQDLSAALG
KMFSSFTLGNYGAQGMIDFMNESKLMDLLNDSDYVPTYEDKDGDWMLVGDVPWEMFVESC
KRLRIMKGKEAAGLAPRAMEKCKNRS
>Sgl59653 E3_adaptor/Cullin_RING/SCF/F-box 13.4 0.2
MRHHIATPSTPATPFVDPTKRPKKRGSYNCGRCGLPKKGHVCDTAAVPTTVSVNPVTPRH
PPPRPQRALSFDNLDVADSFDNEAAVASTAALLDYHHHNNNNDGGGEDDEVYFDGDEIVS
GGLPAICMWEVMTRLPPSSVMSASGVCKGWRDLAGRVWRNTRELRVRVPSHGAVGFVGSL
LKKCCSSLVRISLQMESDVDATLLACIAFSCPNLESLEISTTESSINRITGDELSRFLAD
RRCLTNLKMEGCSNLGSVVVSSSSLSTLWLSDLHSLSKTIFNCPSLREVSLNFSHQENDS
TDIAAMMDNLGKFCPKLQNIHVASPRLSHATVLALTEANLRGLKMLSLVLGSGITDASVA
AIAYSFLKLEHLDLSGSSITDSGIGIICNVFSRTLSRLLLALCPNITSSGIQFATAQLPL
LELMDCGMTICDPNVNEVTGDDSNDYEPPKSSNMHHIYQKLIIKHNQLKKLSLWGCSGLD
ALYLNCPELGDLNLTSCRNLHPERLLLQCPNLESIHAAGCVDSLSRVIETQIENAPLESH
LLIKRMADGSKRVRVPHILSPQPSDDSKQCHVRKRRCIVVKE
>Sgl59670 ULD/UDP/UFD/UBX 44.9 0.0
MNIDSPLAWKRRRLIDIDPMEAEAARAKLEAAKQKYGRELRVLETSTGSQSSPEAANTDE
PDDFFEFTAEDYYVLMGNKKEDKFLKTKKIREAEAAARRSKITKAVVRIRFPDDHILEAT
FHPSEPLQSIYDLLKKVLARPELPHYLYTTPPKKQIKDTRQDFFAAGFIPGAIVHFSYDL
PRDDAAFSGPFLQEDVMSLKGLDLVPETTKEPITETTSETAVVNDRPIVPERKPAEKKAA
KPKWLKM
>Sgl59713 E3_adaptor/Cullin_RING/SCF/F-box 12.4 0.1
MANSSSSSMIIPEIDDANHSLIPNLPNDLSSLILSFIPLPFHGRLKSICKSWRKFYSSKT
PFYLRNTHLPSSSLSHLLCVFPQDPSLSSPYLFDPTFLAWAPLPPMPVNPHVYSLSNFAA
LSIGPHVYVLGGSLFDTRAFPMDRPVASSAVFRYDLVVGRWFQLAPMRAPRGSLAAAAVG
RGKIVVAGGGSRHSMFGAAGTRVGSAEVYDVERDEWAQVAGLPGSRAGCVGFYVGRSREF
WVMGGYGEAKTINGVLPVDEHYKDAVVLGLEDGRWREIGDMWDDNERPRLGKVVVINDDD
DKYLPEVFMLDGNDIFRYNMASNRWFKESHVPKKNQDGSPFGFVALHGELHVISHLQGVE
LSAIKRSRHRRRGNALFMQIYNPRKMSWRSLVTRTPFQCPLDFKTAVMCTIRV
>Sgl59739 E3_activity/RING/RING 38.8 5.6
MDSSLLSQQQQQQQPPPTPHTSNSDFPIAIAVLAILALAILLVSYYIFVTKCCINEGSII
SFSPMLGPIHHRGLDEFLLNNIPTMQYKPNNQNFNKNNLGRSFRGCAVCLNEFEEKEMLR
VLPRCNHTFHLDCIDVWLLNNASCPLCRSNISGRTKYPLDHIIAPSSSPQDLISPMYSGN
LSMISFNGDDQDYLVIEIGDEDATQPSSTQRKNEHNTKLMSRKKLHNFSIMGDECINIGH
KDEQFAVQQPIRRSFSMDSAADRGLILQVQEIVRQNHMQLYCNNNNNNNNEVSSSTSASI
HEECNNNNNSVSGRIRRSSFFSFRHGRGRSRSSSILPIECDH
>Sgl59770 E3_activity/RING/RING 9.1 8.7
MLQIRLNKGASLDGSTGAKPLPGETVTVACPDHLVLADLPVAKGLGSATSASMVKIVGRR
SRRQLAERVHFCVRCDFPIAVYGRLSPCEHAFCLDCARSDSICYLCDERIHKIQTIKMME
GIFVCAAPHCLKSFLKKSEFESHIHESHADLLQPNMKKEEMSESEVSGSKQSSILDTTVR
GPQRSGFPLSSNDRDDKGRRQQPREQPPLRPLMPPKLPPFYGQAHPSDPQPDNRAMGLDG
PGQTRMQQQNVEAQGGTQQDFGQFSDKQQQGLMPDPHREYPQMYPQQPPNFPMPGNGNTM
MMGAPPFGFPPFQSDGAPPFYGASNTYEVARSDSIGEGGSEQGSVLGFAPGPGGPVNYPD
GFPRPWNGGPANVPFEAGQGGQGLMAPPPPPPGPPPPHLMQHKHGYYSGDSSNDGKGYGW
QSERHDGFGSSQD
>Sgl59793 E3_activity/RING/U-box 96.9 0.0
MSCQTAKVMPSQNDFENLAAMLKHLKPVLDEIDDAKIASEEDLWKECEELDIYINAAREL
MERWSSKMSRIVSVSQGEQLLKKIKKSSLEICSILCRLLRTSSSSSFAGVQVCTEIMHCV
QELQSWQPDRISRHIEKALRSKNDNLISCSEHLAEIVESLSLVSNHELLKESIAVERERA
KVHANKQTEEMGDINQIVDLLALIREYLLKNECFGTINGVSIPPYFRCPLSLDFMLDPVI
VASGQTFERSSIQKWLDQGLRCCPKTRQYLSHTNVIPNYTVKGLIANWFQENNVKPPNSS
DRTNGNGLPAQDVIHTDSFHCSVHSSDSLSRSSLEVGDAVGRLNIDEPSVSGEMSSSTCQ
GLETEKSNHQTSEQSYTHSRTHSVTSAVSSCDYVPSSATEMSRISDRREKFGEIISEPSP
LSSSLSGRGSRSVKASSEMNEKGNNNHARVHSFSFSDSGHDETTTSSYVNELVENLNNPS
NAMQTAAAEELRLLAKHNMENRIIAGKCGVIDPLISLLNSDVKITQEHAVTALLNLSLNE
EIKARIAEAGIIEPLIHVLKTGTDTAKENSAAALFSLSLLEDFKMRIGRSGAVKVLVDLL
ARGTVRGQKDAATALFNLSICHENKARIVQAGAVKYLIQLLDSSTGMLDKSVALLANLST
ISEGRLAIVKEGGIPLIVEIVETGSQRGKENAASVLLQLCLNNTKYCNLVLQEGAVPPLV
ALSQSGTPRAKEKAQQLLSHFRTQREGAAGRKKK
>Sgl59794 E3_activity/RING/RING 22.8 10.4
MLVAPTAAQIMISEATNSPLHPSSQISSPAWRTPRIFSPPMTPNNNVWVYESPRRIDYYS
NANWGVTQLNPATAVPSPTPSAPPVSNSNSNNSIIGNDGVSASVAAADTAVQPPEVSNSA
VCVVCWEARVEAACVPCGHVSTCMPCLKKIKDNNEACPVCRAEIDQIVKLYGI
>Sgl59795 E3_activity/RING/RING 21.7 10.3
MGQKQSRDKLMYHYVLNKDVGGIQFLSKQGAGLEWKDKEGKTPLMVAAKESDLYDVAKTL
IEMGANVNAFCKGRKGGTPLHFAARQGLDNTVALLLSHGANAFVENREHHTPLDVARNNG
HNLVVREIESRVCYFAGHIRENFGPGLSDVAVAARSQSSTSAIIWVVVVPRSPHNPPKPP
ILELVIYSTPEDAAPRKIVSLRRSKMKAPRFDQPSPTLTIFDKQTKTRYKFSSVTFNNKQ
QLRRLYNACKGISQAAPSAAQMMASETTNSPLHPTSQINSPAWRTPGISSPPMSPNNNVW
VHESPRRADQYSNANSGATQTQLNPAAVSSPTVSVPLKNNTCSNSNNNNNNNDSTNIIDV
DEGSTSVGADTTIQPAGCDSALCVVCWETRVEAACVPCGHVSTCMSCLKKIKDNKEACPV
CRVGTQILQQSSMEGVKPSDETHSVYLGEIVLHRDEDLEQGVKNSPANDVTTIRGENEDT
KIGEMERTISI
>Sgl59796 E3_activity/RING/RING 23.1 9.6
MGQKNSKDEMVYQKVMEGNVEAIKALFSEGARLEWIDQQGKTPLMAACMDSRLYIVAKTL
IELGANVEAYRPGGHAGTPLHHAAKRGLHDMVKLLLMHKANPFARNDECQTPLDVARAKG
HINVIRVIEDHICYYSGNVRESMAVPGILESLVPHRLTRKSSKKCWVVVVPSGPPNKKKP
PKLELVVYSSRQAHQPRTVIPLWKSNIVEPKFHESDPSLTVINESTKTRHKFISTIEGDM
QQLVQLYSACKGFPKVMPSLVPSSSSGTSPSLPAASASNQPELSSVSNSQSSSNTNGWGD
LDGIATHSECGPSSVPPPTTASCNGWANEPTTEELNGWADPSPGPSRPTISPNVAPPPVP
STPSAPPLPMDDLDEGLIHYPAVDMVPVDLPVASGDAKGKAEDTCCVICWDAPIEGACIP
CGHMAGCMSCLTEIKSKKGDCPVCRAMIDQIVRVYAV
>Sgl59830 E3_activity/RING/RING 16.2 7.1
MEEVVLFIDDDFNNSPNYCRICHEAEFESSRKLETPCSCSGTVKFAHRECIQRWCDEKGD
IICELCLQKYEPGYTAVPKQPKKNVVQHEVVSIRGSLEIPRTEQEPQNVDLLAIAECTAE
AERSASCCRTVALIFTFLLLVRHLIEALLGGAEHQPFSLLTVLILRSCGVIIPMFIIIQT
ISAVQNSIRRHRILHETLMHNTRDTDEEEQLHQR
>Sgl59846 E3_adaptor/Cullin_RING/DCX/DWD 93.2 17.3
MDVKNYASANLMPSLPSKTPSISNKVQESRHFDERDRVTGRAIVADKVPENSHFEGKERV
AGHAAVADVDIDLREVYLLVLHLLSAGPCQKTFAQLLNELMEHQLLPRRYHAWYSRTGVH
SAEENDDGVSVPLTYEKLLHRYPHIAKDHLVRLLKQLMLAPPGLSLGVGNGPNAADVPTL
LGTGSFSLLSCDRIAEKKQVKRVPRYLRWPHSQIDQVHALHLRAIGGGFTRHHRASSIHA
ACYAIAKPSTMVQKMQNIKRLRGHRNAVYCAIFDRAGRYVITGSDDRLVKVWSMETAFCL
ASCRGHEGDITDLAVSSNNALVASASNDFVIRVWRLPDGLPISILQGHTGAVTAIAFSPR
TAYQLLSSSDDGTCRIWDARNSQFKPRIYVPKPVDTGIGTSNQNHQITCCAYNANGTVFV
TGSSDTCARVWNAPKLSIDDSEQPYNEIDLLAGHENDVNYVQFSGCAIIARSVTGDALKD
DQSLKFKNLWFSHDNIVTCSRDGSAIIWVPRSRRSHGKVGRWTKAYHLKVPPPPLPPQPP
RGGPRRRILPTPRGVNMIVWSLDNRFVLAAIMELISDRAVLVCKPYAALGQGKAVLGRRL
LPILQEGPSCRARHVSDCRICVWNAADGSLVHCLTGHTESTYVLDVHPFNPRIAMSAGYD
GKTIIWDIWEGTPVRVFEIGRGKLVDGKFSSDGTSIVLSDDVGQIYLLKTGQGESHKDAQ
YDQFFLGDYRPLIRDALGNVLDQESQFSPYQRNLLDPLCDSSMIPYPEPYQSMYQRRRLG
ALGVEWRPSNIKFAIGPDFSLGEDYQMAPLPDPEAIIDIPEPLDAALWEPENEAMTDDAG
SDYDAAEEYSSAKEQESLGTSSYDDTDSDAENFDVKQRQKDILRRSKRKNERPEAEFTVP
GRRIRRKRVEDCSGTSSQNIRDRRMGSNSKTTKKKKKSLKAKLLRPQRAAARNAKNVFSS
IPETSSLGEDDEDGSEEESSDGGSFSQDSEIQIDEHGWVLQNSFVQGGQKTLFDESATVM
DPIELPESQASVGNKKKLVLKFSVRDSKKSLPKTDDKSEFDPSSSLLQKEEDKQCNFGDE
DVDLHPPAAIYPKPFESSNRVKIKCKGLLEKIPNDTSATIGSDTRREVSCSRQYEKGSRE
DGGDYSIENDLVLSNGNSHELKENAQPVPTRIKIKSSGTIKQERTPKLKLVTGAKKAVAT
EDSSVSYAASYGSDVEENISSTGYYETCPGADFPDADTDVVRRTRSMEIKASTRETGRGS
SKLKLRKSSRSAGPSKISENWSRDSILNSSIPSRSRSSRSRQVDSFEDDQGPPRMSLSNL
GVGKISWLMLSEHEPGYRYIPQLGDEVVYLRQGHQEYIESYATHERGPWVTMKGRINDVE
TCLVEGLIYAPVPGSGESCCKLTLKFVDESSCVFGKSLRLTLPELLHAPDFLVEKTWYDL
AVSRSWTPGDMCSVWWRHENGDGGSWWEGQIISAKPKSSDFPYSPWDRYAVQYQGDPGPE
LHSPWELHNPDFRWEPPHIGFDMRNKLLDYLSKLERRKQEYGLINLEQVSQRPDFLNRFP
VPLSLNVIRSRLTNNYYRSVQAVKHDINVMTSNAMSYFSKNSPHSKKMKRMADFFERMFS
NL
>Sgl59864 E3_adaptor/Cullin_RING/SCF/F-box 15 0.0
MKESKTEVHHHRYVPIDLINDILLRLPVKSLLRCKSVSKSWYYVINDPNFIKLHLRRGLE
TDSNTSLIMIDDHYTQLTQGLMSVVCNVNKHADTNVAHQLCYPKHIIPPYAQCVGSCHGV
LCFLYVPHRRDQHYCLYNPATRAYKVLPVFNFTIGEEFHAIMSIGYDSISDEFKVMKIVY
LLILGCSKIVQHQTLLYSSKADAPPWNDNVLRTSSAVFANNAFHWLSPSSKEIMCFNIST
QRYYVKLVPENISSNSPKLTALQGQLCLVTYEFDIWILKEYDNDEGWTQIFRNLYEIFNG
DDLQANWIFELNISCLRDGSNNNIIIVPSKGRDITRRRMHQVLIYCNLKYGTLKKIDISY
GFEPYNLLLADTQPWVESLLDPAYCRAALS
>Sgl59882 E3_activity/RING/RING 32.6 6.6
MKIFSGNILYDFTVSEIDAPISSVETDEFQIEFHYRKFQSSWQTPDFEARRSIKCHRDST
QSFVTDALQEFEVQENARVDMATHFRFYLDRLLRINMRRRSCSSEGACVKVSLDAKEISP
ERLAEIGRRRERASRRMTVEMTTVTVTETVVNLPAKKAVVEKLERERVVVVDDEKECAIC
LEKFGERGEGIELPCLHVYHKECILQWLGRNHFCPFCRFKLPC
>Sgl59952 ULD/UDP/UBQ/UBQ_PIM 97.3 1.4
MQIFVKTLTGKTITLEVESSDTIDNVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLADYN
IQKESTLHLVLRLRGGAKKRKKKTYTKPKKIKHKKKKVKLAVLQFYKVDDSSKLQRLRKE
CPNAECGGGTFMANHHDRHYCGKCGLTYVYQKAGGD
>Sgl59958 E3_adaptor/Cullin_RING/DCX/DWD 80.6 37.2
MEEHKVWSVNGGQYLGEISALCFLHLPSSLSSLPLLLAGSGSEIILFDVNLGRQIKSFFV
FEGVRVHGITSSCMNYEENSSSVTFKVVISGERIVKLYSLGLQFRSGILDEPDVLADLTL
LQLLPRFTHWVLDFCFLKNGRFSLEEGCCYLAVGCNDNSVHIWDVLMSRLLFKVLCPERC
LLYSMKFWGHDLEALLIASGTIFNEIVVWKLIRQHGTLPITSAEQEPDVMSTLVDVHSQE
CLEYEAEIVSKLAGHQGSIFCLSWSDDGSKLVSVSDDRSARMWIANAELNLTDALTKSPN
LYSAGPVLFGHGARVWDCCISESLIVTAGEDCTCRLWGLDGKELTVIKEHIGRGIWRCLY
DPNTSLLVTAGFDSAIKAHCLHSSLPAISGSSVNKVEERKEEVFRFCIPNSSGQSGLMDS
KSEYVRCLKFARKDMIYVATNHGYVYHVRLSDGGSVECTELIRITEEVPIICMDLLSKNV
SELSLEVEDWLAVGDGKGTMKVIRVICSGGAAHVTVNISWSAERERQLLGAYWCKSLGCG
FMLTSNPRGAVKLWRLPETSSYDSVMNFDVHLVAEFMSPFGARIMCLDASCEEEVLVCGD
LRGNLVLFPLSKRTLFGGSVLSIEKIPSVTYFKGAHGISTVSSISIARINSSLIEICSTG
GDACICYLEYSKDQQTVEFVGMKHTKELSLVQSVNPYHHSLEDSANISYAVGFSSTDFLI
WNILSETKVMQVNCGGWRRPHSYYLDETPEICSGFAYVKDDFIYVHRNCLPDGEKKIFFR
HLHLQFHGREIHSLRFIPEDECATNNFHPKLSWIATGCEDGTVRLTRYNHGIGKWAMSNL
LGEHVGGSAVRSLCFASKIHSVDSKVVEVTSGNPGTNSSLENTECPCLLISVGAKRVITS
WLLRRRLKIEGDASVYGQSSSRPISLMSFKWLSTDMPVKCAHTQKKTQNRKNSVKSLDKV
PASESVSTSIEMELEPHGDVHDNDWRYLAVTAFLVNVAESRFTVCFVVVACSDATLMLRA
LVLPYRYWFDVASLTPLSSPVLALQHAVSPVSHVYQGKLMMKNIYIVISGSTDGSIAFWD
VTESIEAFIHRVPSFHIEKSIDFQKRPRTGRGSQGGRWWKSIGAVTGKEKSDAEVISSDN
GIIDGSPATMILKGKNISSDHTEIASSRSVESLNDLSERLDEIKPLHVLQNVHQSGVNCL
NICSHIIGNGLPFSIISGGDDQALNFFQFVVAPSPTQPNFYDIGKNDRTSESVSPEYLIQ
HDLKQSYSIKFSYQTKSIAAHSSAVKGVWTDGTWTFSTGLDQRVRCWKLQEDGNLIEHGH
FITSVPEPETLDVRSFGGNCYQVVVAGRGMQMVEITLSSGDDKLD
>Sgl59986 UBD/UBC-like/UBD_UBC 158.6 0.0
MSTPARKRLMRDFKRLQQDPPAGISGAPQDNNIMLWNAVIFGPDDTPWDGGTFKLTLQFT
EDYPNKPPTVRFVSRMFHPNIYADGSICLDILQNQWSPIYDVAAILTSIQSLLCDPNPNS
PANSEAARLFSENKREYNRRVREIVEQSWTAD
>Sgl59987 UBD/UBC-like/UBD_UBC 158.5 0.0
MVVTMSTPSRKRLMRDFKRLQQDPPAGISGAPQDNNIMLWNAVIFGPDDTPWDGGTFKLT
LQFTEDYPNKPPTVRFVSRMFHPNIYADGSICLDILQNQWSPIYDVAAILTSIQSLLCDP
NPNSPANSEAARLFSENKREYNRRVREIVEQSWTAD
>Sgl60020 E3_adaptor/Cullin_RING/SCF/F-box 14.8 0.0
MIHQSELLENILSRLPAKSIGRFRCVSKPWKSLLSQPGFIKLHLRRTKCLPRKEYSLMMV
CDESHSLYSAQLKYAHQMSNDTSITTFATKLDFGDRKFSSEECLDTMASCDGLV
>Sgl60033 E3_activity/RING/RING 34.8 7.3
MENFGDGSFEDRDIGVYDYIPKFIGGAVSGALTGVFALAGAFTGAITGALAGRASDSGLI
RGAGLGAVAGAVLSVEVLEASRAYWCSQQSGLRSSSSMADFIEELLHGRFIEEQLPPAVL
TGYYWQASIANVVYDDVYDVYGDYAPCGLSGDSLKELPCHVILDIRPTDNISCTICLQDF
EVGETARRLPHCSHTFHQNCVDKWLITRNSCPVCRRDV
>Sgl60043 E3_adaptor/Cullin_RING/DCX/DWD 37.8 0.0
MSLISQNAVIKDKIKKKKLSRRNDDEGEEPSLMEEGREDLSEDEGSDVEAAVSHKKKKKR
MNKEAKQMLIEEELEMQNLGNFLFGSVHSPVEFGKENEVENQDEVDVDDSALFVMDRSGN
DTLLVDGEDAGYQVGINDEDGDKQRKPAWLDDEEENVVNISKVNRLRKLRKEEDETVISG
LTYVSRLRAHHAKLNPGTDWANLDSKSKPYDSDEESVVDNGAVVASGYKHVDDILKSNEE
LVVKRGSKLLPGIIENSRLVDANAEDPSNGPINSVQFHRNHQLLLAAGLDRKLRFFQIDG
KRNKLMDSIFIEDCPIRNASFLPDGSQVIVAGRRKFFYSVDISKGTVDKIGPLTGREEKS
LEVFEVSPDSRTIAFLGNEGYILLVSTKTKELIGTLKMNGTARSLAFTDDGQQLISSGGD
GQVYHWDLRTRTCLHKGVDEGSINGTALCTAPLGSLFAAGSSSGIVNVYNREEFLGGKRR
PIKTLEHLKTEVNFMKFNHDAQILAICSRMQKSNLKLVHVPSFTVFSNWPPGNKTLNYPR
SLDFSPAGGFMAVGNAAGKVLLYKLHHYQQA
>Sgl60056 E3_activity/RING/RING 31.6 7.3
MWTRASSAIANCVHLKNDLLNRNSECSDDDASFDANQEEGLECPICWESFNLVENVPYVL
WCGHTLCKNCVLGLPWAALKFPTLPIQLPFFVSCPWCNVLCPRMMYKGVLRFPRKNYFIL
WMVESMNGDRTRSYTSGNGEFRQPSSWNGNVGMNTHSHVRNNREISTEGTELNHNNVSLL
RQYFSRERFSVSLRKSLVFVVHLTAKFPLVLIFLLITLYAIPASAAILALYFLITVLFAI
PSFLVIYFAYPSLDWLVREILT
>Sgl60074 E3_activity/RING/U-box 30 0.6
MSFNTDGNSSIVGNFADGIDDVEEFICANVGVLAISNERFQQVFEFVQTGNQAFRRGRFE
EAINCYSKATLVKPGDPIILSNRCAAYIRLSQFLKGRAPSASEYSPLYGLDPTTHAELAL
KDAEKVVSCRKNSVKSYILQADALILLERYELARGAVIAGLTLDPLCTHLQDLLSILERT
CTGLVLERSRVKPERSDDFDCTLCLKLLYEPVTTPCGHSFCRSCLFQSMDRSNKCPLCRT
VLFITPRTCAISVTLNNIIQKSFSEEYAERKLENDNLAKLGVDLMPLFVMDAVLPCEKLP
LNIFEPRYRLMVRRIMEGNHRMGMVTLDSTTGQIADFACEVELTECEPLPDGRFYIEVEG
RRRFRILRSWDQDGYRVAEVEWIEDTCPGEGTREKTELQELARNAAEYAQMWMMRAKEAS
KQDRRRLGEILNVEAMMPSREDPERFSFWLTTLTKRRPSERLELLRLKDTKERIKRALIY
LRQEEQGCRLQ
>Sgl60077 E3_activity/RING/RING 38.4 3.1
MFDIPIHCSHKTTSSSTTPRSISELPPKQLTVYLISTKYQRVVYVNNDNNNDNDNNSTVF
VSRHEHPSIFSRKYVNPVDPSCVSCMPYILGAILNHGYVGATDALGQYRCLREEISRKVA
SMLENNENYSVITYELRKYDHSDFRPCDEEEYRTLVAQGEEFEEVVISDSDVEDEEGLVP
ASESAIERLERVVVDDEGEFVFEDVVSDDRTCSICLEELVMLNEDDDDDDNKSKNKFIGI
IRLPCKHLFHEDCIVEWLRKNHVCPYCRFELPIVD
>Sgl60078 E3_adaptor/Cullin_RING/SCF/F-box 19.9 0.0
MANIVPTKYSKENKSNRSSPSEAKSHSSYWLPEDLILEILVRLPLKSLIQFQIVCKRWKS
LIKNPKFAKTQLHYSNQHHLPSLQLIFQYNSVLASYIDLNDYLDNPTKANEFEPKFVELS
SQPFQKNDYDYMIVGSSNGIICFYLFKDNKLCLWNPIIHETRFISLPPNRKDEYCRHDIL
FSAFGYAPSIDDYKILLLVKKNKYRDRSLIVYSLRRDNWSEYDHQFSKVQYFYDWFRNCQ
RFGRRVEDVVFNDALHFDMGELCSCEPSYIVKFDMVKECFEKVVDLPRAQYYSYWDATKM
VVTEDSKTWYYQPYYEKSYKTDIDTDTGATAVIKRQVVEVFKLLDNNSWEMKVVYQGSWE
DKDGRELYLIRISNNGKVLLFKEMTCGPWLIGKLHILDLRHGEPSFIQVNNEDNPPLETF
PAHKYAKPNSASYVPSLVSPYYSC
>Sgl60079 E3_activity/RING/RING 31.1 6.3
MEDNSLMGVVIHCDHKFPQPLPKQVKQLLMVRFNTRCYQTVVYPNNGTPLVSAQPQPCSP
SNILLDTHRTCNPRCKYCFSEIYCFLVQHRYSDVFDALDEYFRFFDVVEGKVYSMLLGYD
ELNDEEQRSLKFKEDFYYEVGINLGYRLCVEEEYRALVADGVAFEVLMVATPANSDTMLV
IKGVEIVDNNNNNTDFLELLGKEDNNCPICLDEFSVKVNKHEESEDDDPTTVQEEEDTIN
DHDDHNNNNTKDHKLMVRLPCKHVYHRGCISEWVQHDHICPCCRFPLSFDVFL
>Sgl60145 DUB/USP 117.8 1.9
MHLPVLIFQLYGLTVQASFLGESKKYKAAIIRIDSPGGDALASDLPEEADLFAKSAQYAY
AQFRDKAAHSRSMPFLLPLHCSSSKCQIIHWRQGHKHECHPQDHSASEKDDFDENADSVE
QCKTNDISSAEYFSRMDDKNISQHRHDDVFDLPVPRLSTVTVASFDTGRSSCGENETLSS
HIDATKMGHREDKINSMEMNASTGLTPNGAVNSVRKLKKKSRQDDRRKFRPSNSEHSPGS
QQDKSDRTFGNVPSSKAEEVLFVDNDEQKHSSYSVPPRRSVSNELSRNGLASSFQKVVHH
FKASNQKKPSPHDTLLGISANRNCKTIFPYDAFLKLYSSNEVELRPFGPINCGNRYAVDT
MQSVCAELAGVVGPEREESTLVGMTFGGFLHSKIRCLKCNNKSEKYERMMDLTVEIDGDV
RTLEQALRRFTASEMLEGDNKYYCNRCKSYKKAKKKLTIFQAPNILTIVLKRFQAGSFAK
LKKPVQFPEILNMTPYMSDSSDKDKHPQYNLIYILWYECTSLVETTKEIKGATVENNKVD
KMEENAQGRVWTGGDAASRGLVDAIGGMSRAVAIAKQKANIPLEQPVTLVELSRPSPSLP
ELLSGIGSTVGTLASVDGTLKALLQELTSLEGVQARMDGIIFEKMDDASYDNPIISILKD
YLSSL
>Sgl60182 E3_activity/RING/RING 11.8 14.4
MANAASSSTVSFLDWNSGLLVYPEEEQNQESSLCGLSDIGGHLMKIPIIAFQVLLCMRLE
GTPNGARYMPLPVLFSPLFLLQGVGVLFSISRLVEKIFLFLNSDAGQGWYFTFSAKLRES
LAFMHHGSRLLGWWSIDEGSREELAKLLHDGPSGYNTFCSYPPEVVKKMPKKDLAEEVWR
LQAVLSQQTEMNKYTKQEYEKLQNDKVICRVCFERDISIVLLPCRHRILCRICSDKCKKC
PVCRVAVEDRLVTVNLLADHL
>Sgl60210 E3_activity/RING/RING 34.4 42.9
MAVLQQNLPCDSDGVCMVCKHKPSEHERLVCSTCVTPWHADCLVNKPESMASLSKWECPD
CCPEDDDDDDNNGGGGVASVVTGPAGELVAKIREIEADASLSENEKAKKRQELLSGIGSS
DENGGGGGKVKDDNEILQILGDNIKCSFCMLLPDRPVTTPCGHNFCLKCFEKWVGKGKTS
CAKCREPIPKRVASQPRINDSLVLAIRMARSSKPAAAEVPRMIQYVHNEDLPDEAFTTDR
AKKTGKANAKSGRIFVTIPNDHLGPITAEHDPVRNKGVVVGDSWTDRLACRQWGAHFPHV
SGIAGQSSFGAQSVVLSGGYEDDEDHGEWFLYTGSGGRDLSGNKRTNKLQSSDQKFTKAN
ESLRMSCRKGYPVRVVRSFKEKRSNYAPEVGVRYDGIYRIEKCWLKKGQQQFKVCRYLFV
RCDNSPAPWTSDEHGDRPRPLPNVPELKKALQLTERKESPHWDFDVEQGCWMWKKPPPPS
RKGKKTGAGHARKSSKAKLMKEFSCLLCHKVLTLPITTPCAHNFCKACLDGAFDGQKFVR
ERNTGGRSLRTQKTVMKCPSCTTDISEFLPNAQVNRELMGVIESLMRKFEEEEKADSEAS
SGDLNDENEESLSEGAEISTSDAEETASKPAKEEVDVAKEEPEVVEKESKDEAVYENVDE
VKAELADAKKRVAIEEPEVVGKENQKEAVCEDADEVKAELPVAKKRGRPKKNTVANGAAV
SAVTPTGARKSRRLANDGNVSPSSPLHLRSDNELE
>Sgl60213 E3_adaptor/Cullin_RING/DCX/DWD 61.6 2.4
MNGRGILKKPKREIESDNEEEHNKINHNSSKYDDDNDGDDDSVSISNYEEQEEALVALIE
HRSKEVEHLNNRISYYQSQLKQAEQRLDDSQGKLVNVRRKISDLKWNNSAKKEGKKEHRH
RSRSPVNGGSLQRQPHNKPQLLISNTSQKSSRQTPSETGPKASSSHYDSPVKARGDKSHG
TPSRSEDSKSDAVGAKRKLETSEHKELVSKVRNSSSPTMIQCYASTHISSQHKRKIRSLT
LCPVIDKLFITSALDGMVHLWQIQAKGSGATLLSSTECLSPKQRRWPEDIAWHPEGNRLL
SVYSADGGDNQISVLNLNKNQSSRVSFLEEKPHVRGIINCVSFMPWDDTCFATGGSDHAV
VFWNEKDGGDDAWKPKTLHRNLHSSAVMGVAGMRHKPMVVSAGADKRIIGYDVLAGRADY
KYLIESKCMNVLPNPCDHHLFMVQTGTPERQLRLFDIRLRNSELHSFGWKQESSESQSAL
INQAWSPDGLYLTSGSADPMIHVFDIRYNAHKPSQSIKAHQKRVFKAEWHPTMPLLISIS
SDLNIGLHKI
>Sgl60265 E3_adaptor/Cullin_RING/DCX/DWD 57.7 13.3
MDEECKTEINGTQVEGTEIDETQIEEKDSNSQSEVAPALIAVHPFDQSVAVAIGSELRVF
NLAKNCSISLGNESSELLHKDAIRAVRFSDKGKLLVSAGDDKLVKIWSTETWQCLCTVNS
EKRVSAVVISKDEQYVCFADKFGVVWIVDLVGLAENQPCSNKKAVALFGHYCSIITSLEF
SPNGSFIVSADRDFKIRVSVFPRSPLKGVHEIQSFCLGHSEFVSCLTFVHNSDFPQGFLV
SGSGDSTVCMWDVTSGSLLCTSEVGREANLSEESQPAVIDLCATDDGTVVAVAIQRLQGI
LLLSCDLSAAKLSTLKMVPVPGEAFIPTRLGMALSGNFLWMVTGVSNLPGSKAASFARIR
IVSSFKESDLEPRVLEDQEIPGGEQLLEKLQGSVSVDSADFSAAADTLNAAMSSLLRKKQ
YSNEKREFRKKTRNDKKYNQ
>Sgl60338 E3_adaptor/Cullin_RING/SCF/F-box 15.9 0.0
MRNCRRKINWSEFPDEILRFIANYLKDSPKDLHNFRSVCEKWRRATAIPALLPYDMGFET
LFSSSVFLLRSPDSIPPWIVTIVEITKGKLQYCHPLTGEQFLNIPEDFNFRRFNPRRLSL
DFHMSDVNDKCNLSRALFCHDKVLLFFKDQCSVPSIVDDCSLLVLFRGGQLGGSPPVRPE
YQFGTELPWFDISYGSLDKFDEILCFNGAIYALDRLGKLYQMFTHQFAVLKMFVGKPVVK
PDCVHKGWRKRLVGSVSTGKLFMIRRSDEVIRVYELCKVDDKKLWNWVKVESFGDDHKVL
FVSRSYSFFVPATEFIGFKDCVIFSYDAFRPYSKAAETKCDRKEIQIFQLGCHDGGTIKS
LSDFPGFLVENFCPPSWAFQPQTSTFPEDCQSDPEEDEMMEPGPTDQEAGASAQDHVSSP
SRIPKSEEQSVEIPSTSAAQAKSASHLSGFDQKHEEAPDNSDSKDFRADSASVTSSAMNS
MECESNNKFYEGLRIKPNLLPTLQTVWIKHGNPVSESAVRSKDMLSCALESLAKMINVLQ
STTARTLTDSLAKDLDSIMFDLQCVGLKVDWLVPFVKRALAIQKSKPVIESIMAIEKEKD
RVDEEEREFLMRSAKKKQELEDKKACVSAALPFPEPFNLDQCLGEGLI
>Sgl60340 E3_adaptor/Cullin_RING/SCF/F-box 18.4 0.0
MGHSCSASWSSKLPRKLIRNISNRLTTRDQLVRFKRVCRRWRKHSFTLPVNNLSFTLPLT
IPVSKSCKTLPFHSSTRSLVLQVSSIYLITPSHPSQDCHGSLKPWMVMVEESKPGKLRLR
HSLTAKRLNRFPPTLDMSRFRALELARGYSFKNNDRVRKVILCSSTSTCLEVVVLCHDGN
VGKLTVRVSESQAQHKKKKSADSDTEEEEDIDEERVSWKCLKRERSISWFRYLDDIVEFK
KKYLIVDRKGKLYELDIESMKVVRILVSDSVHGEDCVWHSQRQKRLVVDPTSRGLYLVAR
ERSKATRVSFTIYKYNENSNRWDIAEHLGKNRVLFVGVHHCFFAQAKDFPKCKGNCIVFA
ANCFPHYRSNNAPDKALFGDNDDVEVGVYRLGKGDNFKFLSANNPKLSKSIWPPPTWFSS
KRKRKAEETDSDSCTHQDIDEGSSGCSFSDDHEEGMQLDSSSSKPSKASSSKGITDSDED
SEEVQMSSPNEQTCDSENHDFAPPLPIQYEVHDVGTSKMDHQKTGKDSGPDASNVKVETA
NPIPLTPSTKLPACSTVTFEGLDINSELLPTLQTLWGKHGSLISEGTVHDKHIRAYALEL
VAKLVITLQNTPAKNLTDAIADGIKLTLSDLQKVGLKVDWLVPAVENTLTVQKQKPLIES
IQRLNKRKAQVDEEEKQFLARATKVKQEIEKEYMACLSSGIPPSKLINPDDCLAGGLL
>Sgl60343 E3_adaptor/Cullin_RING/SCF/F-box 13.9 0.0
MEMRNKRQKLNWANLPTDVVRSIASFLQEDDNDVNNFRYTCKKWRQATAISTILPLIINP
SSCKKLKLYYSAVSLLRRGPSHGNVPASPPWMISVVEPTKGNIQSSHPFSISSNKRKRDV
QVQHPDDPTRFLMSRCFGRDSFVSKQFQSTILDAAYHLVYVDDEEKQLSSEFDKVMLVSS
RRIPSMHDCGLLALHDGGELGGYMSFKNQDDEEELKWFEIVDYLKSIIKFDDILLYKGKY
LALDRQGKVYTIYIDENNLEINTLVNCPIPLEGRKRSRGRRLVTSSTGTLYLIDRVTQDL
LKVYKLVKVKSESKWERVYTVEDEVLFITRVYCFFVSASEFSTCDLKNSIVFTNNAFPKY
VGTTWEQADAAKNGSQIFVFQFGIDNGCGCVPISRFPDFPLSLWSCPSWASDAMLSSTQF
QRETEEEEDDREDVKQEEEEDGETTASASRKRVKMHSSVTPTLLEFAHPTPNISTSSAVQ
GDTLRIERPSSSSPILQLAEQNIEMNTTYAAQENITRVEMPSEYYSFISEIDEVAERIMN
QMNSLSKIRERATITPATNEQGCAAEEVSHHETLREENEITHSVPRANISSITQGNRTDN
SSTKFEGLDIRSDLLQTLQNISSKHGNLLENITIRSSDMVSKALESLATAVLILKETSAR
SLSDSQANYLDSVLSDLQCMHFKVDWLAPFVEKAVQLHRSKPLMDSRDQLLRRQAKVIER
QSKLIKKLAEVYKLEKEMEEEVANASKLIPFSGNVDLDKPVGLELP
>Sgl60346 E3_adaptor/Cullin_RING/SCF/F-box 11.8 0.0
MASHRKTPRATENWSNPPPEIISAIKKRLNSTIDVLRCRSVCKNWRASINPNPNSSILSP
FLPLKISNPTLPFNNRPNETLILFARTVLLVKPLSSSNDDSTSTSSWILTVEEVTQGKLR
ILHPLSNDRVTSLPPNFPKSLNLLDFSVSEICKSYGFKHASDGKDVCGVHKVVFCSDFTA
MVLYGEGILVSVRLKKGKWGFVRDSLVTPFSDVILFNGNVCAVDCNRNVHTIDHKMMKVI
KSVVDDRILRNSLVSTNGGKRLVERKGKLLLVTWWIGKLCSTDRSETVEVMCYDLNEKLN
AWFETRLLGFVLFVSLNWCFLVCPKDLGISDYLPKIGEQEISSCSYGIDDLQYDTNFPPW
DVKRREYLVLSRTCFNSSALPVFMKYNSQYFEGARVNFSVGLFNYMHEEHDRRNYIYSSI
RGAIWPPPIWFWPDDDTSSRDDEDDEDLEFCVEDVSTDSKQEMPPSLIVPAVNGIAKNNA
QDLRTKEIDMSTFLEDSHALRIQNVNSCASTALFERVKIKANLLTTLQNIWAKHGNILEE
SRIRSGDLIAKALESLATTVLILQRSSGRSLNYIQAEYLSSTLSDLQHMHCKVDWLVPFI
EKALAVHKSKPLVDSLKEHDEAKARVKDTKLKLLNELAKLDEVEDDMKLVFETIPCLESV
DLNESLGEGIC
>Sgl60349 E3_adaptor/Cullin_RING/SCF/F-box 13.7 0.0
MEIERVIDWSELCPEILSEIADRLGTRPNVYNFREVCRNWRYALSYIPPTLPYFSPLFPH
TSDSDLLLFLTRGAIHLLVADGVYLLRPRKNPASSKPLLITVEELFRGKLSIRLPLTRII
ATEHLYKNETFLKTLDLSDFHVYVIARGYTLRATFAANAGLSQRNKLVLFANPAAFEPLS
ISDYTALVWFDHGPVVWVRLSQPSDWGFLGYQGTSKFDDIVNYKGRVYGVDRIGKVYAVN
YDLRWAKGENFRQTLGMECIVSDSISSGCDSDRRKRLVVDSSGVLYLVERVTYCGCIHFK
VYKLNEESSKLDEVSGIGDDQILFVSFDWCFFTLAADFPGVKGNCIIFSKSSFAMYSEST
SVEYFCFGRDGKDFEVCVFHFEDGNVGPITAFHGYSDIFWPPAARFCPKVGKSNPL
>Sgl60389 UBD/Alpha-Helix/UBA 47.6 0.6
MASSVVIKVKYEDTLRRFNVSINGEQHFDLNMEGLRLKICSLFNFPSNANFSLTYRDEDN
DLVTLVDDEDLHDVVRQGLNPVRITVDLKTNMTAPTPVAASAASSTPRESSPIDSQQKFV
PNIPETLNSVPEPLRVAVSKISTELTSKAALASPLLGELMDGLSKMGQSYLNASHSDCGT
TNVGGHAEGSAGSKQDSPSEKVDTLINEGIKHNDIKSFSSLFQSPESIQATREAEPKQPS
PSNCSSHKSKYANSGFCSHKLSTSKCKKKKEIIDYSAGKSGVNEESIKNLNASMKNHASS
KRETSNPNVRSFQFGGNFLGSNPPLGSPIPYNWKPEPFIYKADPMGLVFHKGIRCDGCGV
LPITGPRFKSKVKRDYDLCSICFGRMGNNFDYTRLDRPLFGIHALHPKATKGRTTKFCTT
KDSTDKPFRPVPVTLEDFPLLEQVNGIRARSRLDSRFIKDVNVLDGTVMAPLTPFTKIWR
MRNNGTLSWQHGLKLLWIGGVRFSSSDSVEIELPVNGLNNGEEVDIAVDFVSPELPGQYV
SYWRMADPSGHSFGHRVWVSIQVDASVDLTIQSSSNLNLNLLPSTDGALDSQVLDTSEPA
NVETGDSGFPSMDEQIGDLNFPINDDLLVASDVLCPALAASSSSATSSIRADNGATPEAS
IVSNPDVAADGIHESPSAPPANLYPVINTSDAPSTSCSTEKNDENNLVQSQGKAAVEETL
LKELEDMGFKEVELNKKVLRGNNYDLEQSVDDLCEVSEWDPILEDLQEMGFEDKETNKKL
LVKNNGSIMRVVMDLIAGETPQNSN
>Sgl60392 E3_adaptor/Cullin_RING/SCF/F-box 45.6 0.0
MDALDKDCILPEDLFLDILSRLPVRNLLRFRCVSRSWRSLIDNPSFIRTHHNAQYAMHKA
NGVLPLLLWKHTSTIQGRHLLNCYLLSKQQGNDTILNLSSEIQHDTISITPDDPDLLFNI
ECRGSANGIICLDISAIDKRLSGKDSFFVACGILPLENSSDFKIMVETHVASDISVVYMV
YTLSTNSWNRVCEPSLLGATAFAYLPRMGSCFNGVYYWTARLMKENEPQLFRILSYNFGT
EMFRFSDPPQGALSFANRGDVVWKIGLYKEYLALFLMESGLQVGGTSVEIWVVSEFGEDF
GIPLAWQCLISIKPNFECYSCFGAQRMTGDLLFVMHGGDSCLYSLTTGKIRRGRAVMDAV
DTDCILPEDLFPDILFRLPVRDLLRFRCVSRSWRALIDNPSFIRTHHNAQYNLQKAHAVL
PLFLWNRNLLNCYLLSKQQGNDTILNLTSELQHDTISITPDDPDLLFNICCRGSANGIIC
LQIYAIDKRWSGKDFFSCGLWNPASREFKVVDYPNVPDQHTPGECYVVAFVFDPISSDFK
IMVETHVVSDISVVYMVYTLSTNSWNRVCEPSLLGATAFASLPKMGSCFNGVYYWTASLM
KENEHQLFRILSYNFGTEMFRFSDPPQGALSFINRSDKVVWNIGLYKECPALFLTESVLQ
VGETSVEIWVVSEFGEDFGIPLAWQCLISIKPIFECYSCFGAQRMTGDLLFLMHGGDSCL
YNLTTGKIRRGRAVMDDVDTDCCILPEDLFPDILSRLPVRDLLRFRCVSRSWRALIDNPS
FIRTHHNAQYVLHKAHGFLPLFLWKRTLTIQGHLLNCYLLSKHQGNDTVLNLTSELKHDT
ISITPNDPDLLFNIECRGSANGIICLDISAIDKRWSGKDFFFCGLWNPASREFKVVDYPH
VPDQRTPGECYVVAFVFDPISSDFKIMVETHVASDISVVYMVYTLSTNSWNRVCEPSLLG
ATAFASLPKMGSCFNGVYYWTARLMKENENQLFRILSYNFGTEMFRLSDPPQGALSFINR
SEVAWNIGLYKECLALFLTESVLQVGGTSVEIWVVSEFGEDFGIPLVWQCLISIKPIFEC
YSCFGAQRVTGDLLFIMDGGDSCLYNLTTGKIRRLGISFHMCFEYVESLFPLSRRVIMR
>Sgl60396 E3_adaptor/Cullin_RING/SCF/F-box 108.2 0.0
MNVAVDMHACLYILEAGAIMDAVDTDCILPEDLFSDILSRLPVRDLLRFRCVSRSWRALI
DNPSFIRTHHNTQYVMHKAHGVLPLFLWNRNLRNCYLLSKQQGNDTILNLTSELQHDTIS
ITPDDPDLLFHIDCRGSANGIICLHIYAIDKRWSGKDFFSCGLWNPASREFKVVDYPHVP
DQRTPGECYVVAFVFDPISSDFKIMVETHVASDISVVYMVYTLSTNSWNRVSEPSLLGAT
AFAYLPKMGSCFNGVYYWTARLMKENENQLFRILSYNFGTEMFRFSDPPQGALSFANRGD
VVWNIGLYKECLALFLTESVLQAGKFSVEIWIVSEFGEDFGIPLAWQCLISIKPIFEYYS
CFGAQHMTSDLLFLMHGGDSCLYNLTTAKIRRAVMDALDTDCILPEDLFLDILSRLPVRD
LLRFRCVSRSWRALIDNPSFIRTHHNTQYVMHKAHGVLPLFLWNRNLRNCYLLSKQQGND
TILNLTSELQHDTISITPDDPDLLFHIDCRGSANGIICLHIYAIDKRWSGKDFFSCGLWN
PASREFKVVDYPHVPDQRTPGECYVVAFVFDPISSDFKIMVETHVASDISVVYMVYTLST
NSWNRVSEPSLLGATAFAYLPKMGSCFNGVYYWTARLMKENENQLFRILSYNFGTEMFRF
SDPPQGALSFANRGDVVWNIGLYKECLALFLTESVLQAGKFSVEIWIVSEFGEDFGIPLA
WQCLISIKPIFEYYSCFGAQHMTSDLLFLMHGGDSCLYNLTTAKIRRAVMDALDTDCILP
EDLFLDILSRLPVRDLLRFRCVSRSWRALIDNPSFIRTHHNTQYVMHKAHGVLPLFLWNR
NLRNCYLLSKQQGNDTILNLTSELQHDTISITPDDPDLLFHIDCRGSANGIICLHIYAID
KRWSGKDFFSCGLWNPASREFKVVDYPHVPDQRTPGECYVVAFVFDPISSDFKIMVETHV
ASDISVVYMVYTLSTNSWNRVSEPSLLGATAFAYLPKMGSCFNGVYYWTARLMKENENQL
FRILSYNFGTEMFRFSDPPQGALSFANRGDVVWNIGLYKECLALFLTESVLQAGKFSVEI
WIVSEFGEDFGIPLAWQCLISIKPIFEYYSCFGAQHMTSDLLFLMHGGDSCLYNLTTAKI
RRAVMDALDTDCILPEDLFLDILSRLPVRDLLRFRCVSRSWRALIDNPSFIRTHHNTQYV
MHKAHGVLPLFLWNRNLRNCYLLSKQQGNDTILNLTSELQHDTISITPDDPDLLFHIDCR
GSANGIICLHIYAIDKRWSGKDFFSCGLWNPASREFKVVDYPHVPDQRTPGECYVVAFVF
DPISSDFKIMVETHVASDISVVYMVYTLSTNSWNRVSEPSLLGATAFAYLPKMGSCFNGV
YYWTARLMKENENQLFRILSYNFGTEMFRFSDPPQGALSFANRGDVVWNIGLYKECLALF
LTESVLQAGKFSVEIWIVSEFGEDFGIPLAWQCLISIKPIFEYYSCFGAQHMTSDLLFLM
HGGDSCLYNLTTAKIRRAVMDALDTDCILPEDLFLDILSRLPVRDLLRFRCVSRSWRALI
DNPSFIRTHHNTQYVMHKAHGVLPLFLWNRNLRNCYLLSKQQGNDTILNLTSELQHDTIS
ITPDDPDLLFHIDCRGSANGIICLHIYAIDKRWSGKDFFSCGLWNPASREFKVVDYPHVP
DQRTPGECYVVAFVFDPISSDFKIMVETHVASDISVVYMVYTLSTNSWNRVCEPSLLGAT
AFAYLPKMGSCFNGVYYWTARLMKENENQLFRILSYNFGTEMFRFSDPPQGALSFANRGD
VVWNIGLYKECLALFLTESLLQAEAGAVMDAVDTDCILPDDLFPDILSRLPVRDLLRFRC
VSRSWRALIDNPSFIRTHHNAQYVLHKAHGVLPLFLWKRTSTIQGHLLLNCYLLSKQQGN
DTILNLSSEIQHDTISITPDDPDLSFNIECQGSANGIICLRIYAIDMRRSGKDFFSCGLW
NPASREFKVVDYPNVPDQHTPGECYVVAFVFDPISSDFKIMVETHVVSDISVVYMVYTLS
TNSWNRVCEPSLLGATAFASLPKMGSCFNGVYYWTASLMKENEHQLFRILSYNFGTEMFR
FSDPPQGALSFANRGDVVWNIGLYKECLALFLTESVLQMGKFSVEIWVVSEFGEDFGIPL
AWQCLISIKPVFECYSCFGTQRMTGDLLFLMHRGDSCLYSLTTGKIRRAVMDALDTDCIL
PEDLFLDILSRLPVRDLLRFRCVSRSWRALIDNPSFIRTHHNTQYVMHKAHGVLPLFLWN
RNLRNCYLLSKQQGNDTILNLTSELQHDTISITPDDPDLLFHIDCRGSANGIICLQIYAI
DKRWSGKDFFSCGLWNPASREFKVVDYPHVPDQRTPGECYVVAFVFDPISSDFKIMVETH
VASDISVVYMVYTLSTNSWNRICEPSLLGATAFAYLPEMGSCFNGVYYWTARLMKDNEPQ
LFRILSYNFGTEMFRFSDPPEGALSFANRGDVVWNIGLYKECLALFLTESVLQAGKFSVE
IWVVSEFGEDFGIPLAWQCLISIKPNFEYYLCFGAQHMTSDLLFLMHGGDSCLYSLTTGK
IQRLGISFTMCFEYVESLFPLSRRVIMR
>Sgl60417 E3_adaptor/Cullin_RING/SCF/F-box 16.8 0.0
MEKTGEKKKQENFLSFSYLPNEVIFDILVRVPAKTLLQSKTICKEWKSIITSPLFARTQF
RFFKQQFHLPSHYLLSRYVTSFAVDLNRNDDFRHNITAKELENQVMPLSSKYFKLTSAKD
VLLSTCHGIMCIYYVEKSNLLLWNPTIDECRFVSLPYENYKIHRFYYVGFGYASSIDDYK
IVIAIEYLAHNCINYRKSISVYSLRRNEWRELDFEYCNSIIPELYSKLGYHTDRRNAMRV
ESIVMNDALHWVIGRHKCNKNMKFFLYKFDLVNECFEKVVDLNRISVLTDDEEDDKLAPR
QIEIGVSENNRLMIYKLYSDIPTTRTDHISKKMAIKRDVVKAWEMVDQYDYISWKTKFHY
VGRWDDMRDDHDLVQITGDGNVVIIGGSFAEHNNRIELQKLQIQKVDFYAAHYVPSLVSP
NNF
>Sgl60451 ULD/UDP/UFD/UBX 57.3 0.0
MSSSNMRDNPRTRSGDNPSCSGIVRRMVNLPRSILGGLRAMGNGIDFMGSRERRNQIFPP
APPPPPPPFLPPPQFPVFPPHYEPQTALVNEEWTFLNNFEQNYGVSHPFFYACRFIQALK
IAQDEKKFVFLYLHSPDHPFTAGFCSQTLSSEIVVQFLDANFVSWGAIADKGEGLQMSGI
LRPASFPFSAVIAPTPAPGDNIAVLQQIEGPVSPAELLEILQSTLEEQGVAFGSTRAKEE
DRRREDRRLREEQDAAYVAALKLDQEREKLRNIPPQQTVQKSEPPTLASNRGISEWLRKT
PNQVEESAATNRENLDNDSLNKGKNQVTQILIRFPNGERKEHSFSATDKVQAIYNYIDSL
RLPGIGNYRLVSSFPRKVYGVDETDMTLQEVGLYPRASLFLDLL
>Sgl60461 E3_adaptor/Cullin_RING/DCX/DWD 45.4 7.5
MDFGHCCLEGNTDAVEFCPHDGFQNILAVATYTLQEGDPPSRLGSISLFDVSSKSRSFNQ
VGIVETAGIFDMKWNPAGCASSPLLAQADADGCLRIHELECSSSGPTLTGALLKEKCGIQ
ISSSMCLWLDWNPLATSLAVGLSDGCVSIASLAVSQLVEDQQWKGHDFEVWTATFDTHQP
AVLYTGSDDCKFLGWDLRVGSSMPAFQNSKAHTMGVCCIVKNPSDPYSLLTGSYDEHLRV
WDVRSISKPVNETSISLGGGVWRIKYHPFVKDLVLAACMHNGFSIVKIDSDSPKVIETYN
KHESLAYGADWQRYMPDNQEGKKEDNAVATCSFYDRMLRVWIPEADVLA
>Sgl60500 E3_activity/RING/RING 33.8 5.9
MAIRGVDFKWYDGFFLSMLATSVVIVGINWKRYHLCTYPLHVWIVVDYTTVFVFRLLMFV
DNGLAAGMGLDFGWQQRYARFCGRIAVLSVLTLVLYPFLWGWTVVGSLWFTKGKDCLPEE
GQKWGFLIWLMFSYAGLCCIAFICVGKWLLRRQTHMARAQQGGVPISEYRVLVDMIRVPD
WAFEAAGQEMRGMGQDAATYHPGLYLTTAQREAVEALIQELPKFRLKAVPTDCSECPICL
EEFRVGNEVRGLPCAHNFHVECIDQWLRLNVKCPRCRCSVFPNLDLSAISNLRAESEQER
TSATVVTTAQYVRAQTPSQSYRLRLQGLLRPVRSSENVGSGNESENALEVAENGGIFTNP
GPARVNPSPYHVEHDVAAPSSVSSH
>Sgl60509 E3_activity/RING/RING 29.4 12.2
MDIIISIFLLFVGIAILVIIHICIVGRAFSREFFGSDGLPIIKGAGLSVQDLKKLPAFEY
SQSQQQQQQQQTEDNSCNVKEHSIVECSVCLEPFKRGDQCRLLPNCHHFFHAYCVDAWLM
KSPFCPICRTCTTFVATMLSPKVGSADMDMAHQEGNNHHHVLSATTATSYVVAEEVC
>Sgl60511 E3_activity/RING/U-box 105.3 0.1
MIRKIDPDNRRILNFPAVRPCESISPAILLTSLITLSTEITTFKSKFFPSQKRLIREVIR
QIVILQFFFEEIRDQQPRFTKSLVLCLSELHYALQKMHFLLQDCTREGCRLYILMKSQFI
AGQFGVLINSIGTSLDILRLNSLGINSEVKDLVELLAKQAQKARVGVNLNDQCAMERVIL
ILNQFENEFEPERGLIKRVMDYLGIYTWGDCNKEVKFLEEELNNVEDEQEREITLISNLL
GLMCYCRGVIFENLDENEEIIGKSVGELLNCLNPEDFRCPISLELMMDPVTVSTGQTYDR
GSIQKWLKSGHLLCPKTGEKLKTTEVVPNTALKKLIHQFCTDNGISISKPGRRNKDTAKA
GTSPSPASREAMRFLAQFLAARLTYGADEQKNKAAYEIRLLTKSSVFNRSTLIEMGNVPL
LLDLLTSTDANTQENAIAALLKLSKHYKGQKSIIEEGGLMLVIQVLRRGLKIESRQIAAA
TIFYLSSVDKYRRLIGSTKEGIPGLIELIKYGTMCGKKNAIAAIFGLLLYHRNHEKTLEA
GIVPTLIDLLSTIERSDLLADSLAVLACLAEKVDGSIAILQTSALPLIIGMVKSSISKAG
KEYCVSILTSLCNNGGDEVVAILAKEQALMPCLYALVTDGSAYASKKARSLIDMLQKFQE
SSSSNWAAASKVHKERFVDAEFS
>Sgl60526 E3_activity/RING/RING 31.3 9.3
MSNLATQFKESDSISISPSPTSPFQSPSNSNNSPNSSSSSNNSNKISPVILLIIVVLAMI
FFVAGILHLLIRYLMKRPSFYSSSSSVSNSRNPENNNSNSGALQRQLQQLFRLHDSGLDQ
ALIDALPVFYYKDIMGLKEPFDCAVCLCEFSDQDKLRLLPLCSHAFHISCIDTWLLSNST
CPLCRGSLLGSELENQEFSLEFWRALSFGRSINCENSFHFGNSFNNSSHSHSVKPTIMEE
NASERRVFSVRLGKFRNVDDRGDTNNITNKVYESGETSGRGSGREGGGGGVDGSSSRQLD
ARRCYSLGSYQYVVADSNLQVALSTDVDVSGTKIEKLMGQCGGNSMVEGDIEGKKISRRN
KRDSFSVSKIWLWSKKSKFPGSSENNANNHGPPPLNVVLPLSTRDHLDFP
>Sgl60527 UBD/UBC-like/UBD_UBC 99.2 0.0
MSSPSKRREMDVMKLMMSDYSVETINDGLNEFYVMFNGPKESLYEGGVWKVHVQLPDAYP
YKSPSIGFVNKIFHPNVDELSGSVCLDVINQSWSPMFDLLNVFEVFLPQLLLYPNASDPL
NSDAASLMMKDRQQYDQKVKEYCDRYAKKENANGSAAEDESDEEDISDGNCTSSDDEIAG
KADP
>Sgl60533 E3_adaptor/Cullin_RING/SCF/F-box 16.8 0.0
MRNRKKGTPLPEHYHFPPELLNEVLGRLPPKTLLRFRCVCKSWCSLIDSPDFIDFHLHLY
PNNCNKTQLFVKEKVPKTCYETVITIRRSDTFRKVSQCVKIPNTVMGCRSNMVHGLMLMK
SICDELSLWNPSIQKLVRLPFCPFKFDYADARCMLGFSPLSNDYKVIFCKLIDTTAFEVG
IAVYSLRGECWRVKNNRLTVSKCCFDELKSRRGAIFVQGFVYYRPNQCWWYNKDTELLCF
DFDAEDFSFLKLPEMEVEMYRMIFAFGGSLGLLGVSSVRTCIWKLEKNDGVEPWRPYWNG
DTNLDVYAFYKDSSNNYKETMYIEHTGKLLLQSMKKLIAYDFRSNQTKRLGKSIPLRYVD
TYVESLVLHKGHNDAASTSHG
>Sgl60535 E3_adaptor/Cullin_RING/SCF/F-box 13.8 0.0
MRNRKSRKQLPEHYHFPSDLWSDVFSRLTPKTLLQLRCVCKSWCSLIDSLDFIDCHLKFN
PRNCAKTQLLVEERVPKTRSDTKFTVRRSDTFRKIAQLVLPSKFHMVYKSPTIHGLMLIE
NSRENELCLWNPSIRKSVLLPPSPLKFDFWNYSCLLGFAPSSKDYKVFVCKLVDAKAFEC
AIAVYSLRNHSWSVKHNSLKVPRWCYEELKCQKGTAFVQGVVYWRPTYYRRHNDSIELFS
FDFDNEEFRYLKLPEMEEDMYRFIFELGGSLAVLGISSVRSCIWVMEKKGEIELWRHYWQ
GDTNSDVFNFFADFTYNEFELLFDEDIGRFFIQSNRKLMAYNIGSNQAQWWAKYVRLRYA
ETYVESLVLHKGYEGVALTFHE
>Sgl60555 E3_adaptor/Cullin_RING/SCF/F-box 14.1 0.0
MSFLDTKMEIDMIPSKNLLPELWMEIFSKLPAKILVKLRCVSKSWRSMIDNPSFISMHMS
QFKNNLNKHFLLCFETHSLLDEDEFELKIRVRTMGKFRKREQILSVTFSAVDYLIDYKGY
VDGLLLFGRYYEGSYDLFLLNPSIRKSIVLPQIPPSPAGRAETVIGFDPVKNDYKVVMIL
FPIRLVELSFPDSILVYEFRTGVWRFNTGIEIPDQWYLGESVLTRGVVHWLSFNLSMDLP
LPKNFTHIVSFNFGSETFSYTELPGDRSDDCEKITYPFLLGDSLAVLDISLDELDVYHAN
FCIWVMKKCGGNWTESWSKWLHKVIGLDTFGFFKEHKYHIRNLLYVDSIQKFMLEVNGKV
KSYDLENHKMKDLESTDGCYSMDPYVESLLLCKGLEDCDATETEEIDREE
>Sgl60558 E3_activity/RING/U-box 53.5 0.3
MGGKGNGKFLKLNFSFYKNSPSRSCSTPPQPQSQQPPPEYICPICNTLLSDPVVVGSGHT
IDRLCLEVCEAHNFSPKLPDGTRPDFTTKIPNLALRSAIPTWCTKNGVTLPTKDKASIER
IVIGMLEKDEQQNRDSSNNNNQNDELKKIRPSERFLLDSVTDKPDPDYSHAVTELTHRVN
RFDSSTSSEESVIAAPVSPLTPLPFTTRPACWSPFHDHNNNTSSSSETLNSDEMMMMNSN
SNPNFTISEDDEFIAKFKSCDPFNQEQGAASLRKATRTDEKARINLCTPRLLLAIGSLLF
SNYEKVQINAIAALVNLSLAKPNKIKIVRSGIVPTVVQLLKGRLSETQEHAAGLIFSLSL
EEKNRTAIGVLGALPPLLNSLLRSESERTRSDSALALYNLSLDHSNRLKLVKQLNAVTPL
LAVLRQEKEAISGRVLLVLYQLAASAEGKAAMLDGNAVEHLVAMLRKGRDEFESESTREN
CVAVLYALSHGSMRFKALAKEARAVEVIKEVEENGSERAKEKARRILTMLKGRRESGDED
VDWEAILEGGISGGDGGGGVSRARYRAGVSPGVGKTTEF
>Sgl60563 E3_adaptor/Cullin_RING/DCX/DWD 96.2 6.4
MSTFGSNTASTTSHNPNKSTEVVSPPGDSVSSLCFSPKANFLVATSWDNQVRCWEVTKNG
MNTATVPKASISHEQPVLCSAWKDDGTTVFSGGCDKQVKMWPLLSGGQPVTVAMHDAPVK
DVAWIPEMNLLATGSWDKTLKYWDTRQANPVHTQQLPDRCYGFAVSHPLMVVATADRNII
VFNLQNPQTEFKRITSPLKYQTRCVTTFPDKQGFLVGSIEGRVGVHHLDDAQQSKNFTFK
CHRDGNEIYSVNSINFHPVHHTFATAGSDGGLNFWDKDSKQRLKAMSRCNQPIPSGAFNN
DGSIYAYSVCYDWSKGAENHNPATAKSYILLHSTQESEVKPKPRTNTGRR
>Sgl60568 UBD/ZnF/ZnF_UBP 93.1 7.2
MEEATSAASASTHLTSDLPSNTIVSDESSTMISTQTLSFSSGNPRIEETSGVMHLYSNDL
TSSSSSSPLHLPVGRKPLVCVVGVPNHMTYADFCRFSGSFIQHMLEMRIVRNDEAEDTYI
ALIRFDDQDSTDGFYKHFNGQKFSSLEPEACHVLYIVDVQYTGSIERGQASLLSSTEQPT
CPVCLERLDQDTSGILTTICNHSFHCSCISKWTDSSCPVCRYCQQQPEKSTCIICETSEN
LWICVICGFVGCGRYKEGHAIIHWKETQHCYSLDLETRRVWDYAGDNYVHRLIQSKTDGK
LVELNVPCSHGMHGCGSCECSGDPGINEAVLSSKVEAIVNEYNDLLSTQLENQKLYFEAL
LQEVKEETEKEIAEAVDKAVSLKLQKLQAKLDRCIKEKKFLDDINENLSKNQEIWKAKIQ
EIEEREEKAIRLKDGKIRDLEEQLKDLMLDLEAGQAVEQQSLSDEVKSGSVLKIGGESST
SGASKSKNRKKR
>Sgl60648 E3_adaptor/Cullin_RING/DCX/DWD 96.2 6.4
MSTFGSNTASTTSHNPNKSTEVVSPPGDSVSSLCFSPKANFLVATSWDNQVRCWEVTKNG
MNTATVPKASISHEQPVLCSAWKDDGTTVFSGGCDKQVKMWPLLSGGQPVTVAMHDAPVK
DVAWIPEMNLLATGSWDKTLKYWDTRQANPVHTQQLPDRCYGFAVSHPLMVVATADRNII
VFNLQNPQTEFKRITSPLKYQTRCVTTFPDKQGFLVGSIEGRVGVHHLDDAQQSKNFTFK
CHRDGNEIYSVNSINFHPVHHTFATAGSDGGLNFWDKDSKQRLKAMSRCNQPIPSGAFNN
DGSIYAYSVCYDWSKGAENHNPATAKSYILLHSTQESEVKPKPRTNTGRR
>Sgl60707 E3_adaptor/Cullin_RING/SCF/F-box 16 0.0
MGGIFSLKSSGDRNCQNYEGTASGCKRQRVTTCFEHTTRLVPSLPNEISLQILARVPRVY
YLQLKLVSRSWKEALSTSEIYKLRREFKMTEEWLFILSRVEENLLWCALDPVSQKWQKLP
PMPHDSAHDESKRGLALVQMWNALGSRGKIADAIRGWLGGGDPLDEIPFCGCSIGAVNGC
LYVVGGLSKTSALSCVWRYDPILNSWNEVSPMLYGRAYSKTGVINNKLYVVGGVSRHRGG
LTPLQSAEVFDPETEQWSEVPSMPFSKAQIMPTAFLADLLKPIATGLTAYKGKLYVPQSL
YCWPFFVDAGGEIYDPETNSWNEMPIGMGEGWPAKQAGTKLSVVVDEELYALDLSGSLDN
AKVKVYDHRDDSWKIVSAEVPMTHDQADAESPYLLAAFRGKLHVIIKDGNSDITVLQATT
GSLAQPSQSNQSSSRSSSSGSSVTSSPPAVTWNVIASTRAGPAELVSCQILRI
>Sgl60708 E3_adaptor/Cullin_RING/SCF/F-box 15.9 0.0
MKLRLRSLETKQTQNIEVPNNCNLQQLKQIIILQLFSSSSTIQQNLTLSLNGKEQLFGSS
PEESIQSIGVTSGDLIYYSQNPFAFSSQIPNFSHVQLENENSREINIINCDKGDNLMNTH
EVESGKSDELNNLDVEIRDLMEGTSNLVDSGDHSDDLGKTQVLELCKDDELIGSSSRIRE
SSDYDEENSTELMEESNDQEVDDESEVEGNCRFSVPSFLKKIFVKEVRDAADNGSDHKLL
VIAVHAVLMESGFVVYDPILRKKADSFRLADEWPSLAFGITLYYTLPEAPTSEGVETVVL
KFQSLGKFMTIYGSLPKKGFRVHRVCLDEPLFVPAFSYIWKKSDYTGSENEIGGSRKLFP
NHEIFEFWKIVKDGLAYPLLIDLCEQMGLVSPPCLMRLPTELKLKILEFLPAIDVARVEC
VCSELRFVASNNDLWKLKYEEEFDCAVASQRECQWKARFSSLWDIRKRRKRVCMPPLRWQ
EPPQFRPLFPGRRNRNRFGPPFIIGGDYDRLPAFGIPQHPGRRIFRRNCDVGGLGRIRIS
HR
>Sgl60733 E3_adaptor/Cullin_RING/DCX/DWD 72.1 8.8
MGVKRPRSAVVDVWQREVGQISSRNFAHRLAASEDLVLRLDILRKLVKHRGCVNTVSFNS
SGDILVSGSDDRKVILWDWEVGHAKLSFHSGHVNNVFQAKMLPYSDDHNIVTCAADGKVR
LAQILEGGHVETSLLGSHKGRAHRLAIDPGSPHVFYSCGEDGLVQHFDLRTKDCTELFIC
HSTFGRRRNSSFVHLNAIAIDPRSSNLFAVGGSDEYTRLYDIRRYKWDGSSDFGQPINFY
CPEHLIGSKQVEITGLAFSDKSELLVSYNNENIYLFTKDMGWGPNFAPSSLSTCSDTAHE
PEDDDPSEATKSVLDTNKKPIPQVYKGHHNCDTVKGVSFCGPKNDYVVSGSDCGRIFIWR
KKDGELIRVMEADRQVVNCIEAHPHTAVLASSGIESDIKIWTPKAEERATLPANIYEVKC
GRPYFFDSDEDETSFSDDDGDDDDSEDDEEMYEYDNNSYDDEDDDYYDDDDVDEDDDEVE
DEDDDDYDGGGSGGGGGGGGDINLRPRQRGLMNGASSPQELIMQLFSLQNRRFSSPEPED
SEENSGLRQDFIDLMLSMSRRSDDTSDDGAGDESGPEDFYS
>Sgl60739 E3_adaptor/Cullin_RING/SCF/F-box 11.7 0.1
MASFSLTSSFHTFNLPNLRHSPPQPRLLRFQIKCSAQSPPSMPNTASSTVQFDLRSYWTA
LIQEINHKLDESIPVSYPEKIYEAMRYTALDTAAKRAPPVMCITACELFGGHRTAAFPTA
CALEMVHAASLIHDDLPCMDNDQVRRGHAANHVVYGEDMAILAGDALFPLGFSHIVSYTP
RELVPETRVLQVIAEIARTVGSTGMVAGQFLDLEGGTNGVDFIQEKKFGELAECSAVCGG
LLAGANDDDIQRLRRYGKAVGILYQVVDDILKEKAKIGRNDGKTKLNGKSYVSVYGLEKA
QKVAEDLRAQAKSELDGFESYGEKVIPLYSFVDYAADRGFNVGGYPHCLWRRHAKLPILA
GVTLFCLRFNHIVSYNPHEASPRVAEKNRDGRRRRRRRRRRKMALEQLPSTLLATIIAKL
DMASICSVASTCRTFNSCASHILTFLPTVHLLDVAPSMDLLVPLLPQNPYLTSLKVDCCR
LDDTAINRLIRPSLHELFLHNCGDFSGRLLSEIGGHCHNLRSLYLGSVGDKRGRAVHISD
LEELLKGCAELETLNLMFDVSTFLRHNFARRGPWPLQT
>Sgl60808 ULD/UDP/UBQ/UBQ_PIM 84.4 0.0
MGAEGDSSDTNVAVTEEVSVNIRCSNGSKFSVKTTLDSNVSAFKSLVAQNCDVPAEQQRL
IYKGRILKDDQTLESYGLQADHTIHMVRGFAASASTAPSGTTAASDTTPAAAQAAAPAPA
ANPAEGGGLGSAGLGASLFPGLGGLGGTGASGVLGAGLPDFEQMQQQLTQNPNMMREIMN
MPAIQSLMNNPDLMRNLIMSNPQMRDIIDRNPELAHILNDPSILRQTLETARNPELMREM
MRNTDRAMSNIESSPEGFNMLRRMYENVQEPFLNATTMAGEGGNNQASNPFASLLGNQGA
VGGQQTDGSQNPSTTGSETGVPNTNPLPNPWNSTGGGTQTNSAPRANSTGDTRPSPLGGL
SSLPELDRMFGGAAAGGGGVPDASMMNQVLQNPAISQMMQSMLSNPQYMNQILNMSPQLR
AMTESNPQLREMMQNSDVLRQLANPEMMQQMLTMQQSLLSAMNRPQSNQDQSPNAGAAPA
AGNANNNMGLEMLMNMFGGLGAGGLTTPENSNVPPEELYATQLTQLQEMGFFDAQENIRA
LQATRGNVNAAVERLLGNMGQ
>Sgl60828 E3_activity/RING/RING 37.8 5.9
MASLHIHRKLLPANSPDEYSSEDLTVETCLYFCNSQRNNTSPKPGFCPEACLAICPSVCH
YSLTDVPFPPPAIPNKSQNLSPLLLCMLILLASTFLLITLYILYTKLYYHFYAPNSNNSF
LQRRSRRRRRESDAGSYSVDEENRNRVVFHPFWSIPTVGLPPAEIRSIPVHKYGKEMEER
DCAVCLAEFEEGDELRVLPKCNHAFHIPCIDTWLSSHTTCPLCRSPVTSPDDDHNSDHDH
PHKAEDTSSSLTSMEGAREDDNSPAEVLSITVTGGEEVENNTNENHTENSRNKDQENPRR
VNEGSSSSSQRWSLERGAANLLSRSLSCSGKIFSSRSSNIRPSPNS
>Sgl60834 E3_adaptor/Cullin_RING/SCF/F-box 17.1 0.0
MGPLPIDIISNILARLPVKYLLRSKSVCKSWNALISSKPFINLHLQLNSISTSDKLLLFS
TNDHSLYSLTLDSLESPATKLNFFNNNDSSFSGFGGSCNGLLLCFTNTGGSNSGVCLVNP
STLQYKMIPRLKVPKSCVCVNYGFGYDHIHDDYKVVRVINLVYGCENTSVFNAREVMVYS
LRNNSWKFIEEKVSNYATLASRNGALVNDHLLHWVFWCISSNRHRISSFDVCSEQWGEVP
MPCYVRGNLRENPSNVDVWIMKEYGVKESWTKLLNVSDLNVIPIAYSENFKEILFRKEKK
LSVFWYDLRRRTSRNVEICGLQDCCGVTSCIRTIVPLNCHGEIDD
>Sgl60851 E3_adaptor/Cullin_RING/DCX/DWD 129.4 11.8
MLTKFETKSNRVKGLSFHSKRPWILASLHSGVIQLWDYRMGTLIDRFDEHDGPVRGVHFH
KSQPLFVSGGDDYKIKVWNYKLHRCLFTLLGHLDYIRTVQFHHENPWIVSASDDQTIRIW
NWQSRTCISVLTGHNHYVMCATFHPKEDLVVSASLDQTVRVWDIGALRKKSASPADDILR
LSQMNTDLFGGVDAVVKYVLEGHDRGVNWAAFHPTLPLIVSGADDRQVKLWRMNDTKAWE
VDTLRGHMNNVSCVMFHAKQDIIVSNSEDKSIRVWDVTKRTGIQTFRREQDRFWILAAHP
EMNLLAAGHDSGMIVFKLERERPAYSVSGDSMFYAKDRFLRFFEFSTQRDTQVIPIRRPG
SASLNQGPRTLSYSPTENAVLVCSDVDGGSYELYVVPKEQFGRGDMAQEAKRGVGGSAVF
IARNRFAVLDKTNNQVLSKNLKNETVKKSPLPIATDAIFYAGTGNLLCRAEDKVVIFDLQ
QRIILGDLQTPFVKYVIWSNDMQSVALLSKHAIVIANKNLVHQCTLHETIRVKSGAWDDN
GVFIYTTLNHIKYCLPNGDSGIIKTLDVPIYITKVFGNTIFCLDRDGKNKSIVIDATEYI
FKLSLLKKKYDSVMKMIRSSQLVGQAMIAYLQQKGFPEVALHFVKDERTRFNLALESGNI
QIAVASAKEIDEKDHWYRLGLEALRQGNAGIVEYAYQRTKNFDRLSFLYLITGNTEKLNK
MLKIAEVKNDVMGQFHNALYLGDVVERVKILENAGHLPLAYVTASVHGLHEVAERLASEL
GDDVPTLPEGKKPSLLIPPAPVMCAGDWPLLRVMKGIFQSDFDGADRVAAEDEEDIDTAW
GEELELYDAEKVENDDDDAVFNADGPVADDNEEPGGWDLEDLELPPEDDTPRASISARSA
NFVAPPSGTPVSQIWIQRSSLAAEHAAAGNFETAMRLLNRQLGITNFTPLKPMLLDLHTG
SHSFLRAFASAPVISLALERGWTDAASPNVRKQPALVFNFSQLEEKLKAGYKSTTQGKFS
DALRIFLGILHTIPLIVVESRREVDEVKELIIIVKEYVLGLKMETKRRELKDDPKRQQEL
AAYFTHCKLQMPHLRLALQNAMTVCYKAKNLSTAASFARRLLETNPGDQQKKLAEQVERA
AVKNMNDAIELDYDFRNPFVVCGATYVPIYRGQKDVSCPYCSARFVPSQEGQLCNVCELA
VNGADASGLLCSQTQIR
>Sgl60866 E3_activity/RING/RING 20 14.5
MSEATEQNQQDQAETVCSFARKPLRNKNIRKRPSDDNEDGSEGSSMLTTNKKLAKTDNKL
CFSSGTTKRSAPAESTEDSKNMFFQYESSKEIQVQNDSKATATLETETDFSRDARAIRER
ALKLADEGLKGKNKSGEKVYKGMHNYTDYRAGFRREQTVAAEKAGGAHGPLRASSHIRVS
ARFDYQPDICKDYKETGYCGYGDSCKFMHDRGDYKSGWQMEKEWDEAEKTRKRNLALGGH
DSDEENAVNDEEDDDDALPFACFICREPFVDPVMTKCKHYFCEHCALKHHTRNKKCFVCN
QPTLGIFNTAHEIRKRIAADKKKADNN
>Sgl60903 E3_adaptor/Cullin_RING/SCF/F-box 16.8 0.0
MATFPPEIITEILSRLPVKSLLRFKIVCKFWHFLIETPNFVKLHLNLSLISNSNLHLLLY
YPYLYSAELNPHHNHLSFSTLHHPLEPRQVHLLGSCNGVICISDPSKTDTFLFNPLTKSQ
FKLPDNRIPDLSPAVILFGFGFDAKSDDYKVLRLVQGYKIGKVYYEETKVFSLKTNSWKS
VGGTSFYLFDVDCHGVLVNEALHFTVILKESKSKGHLIAKFDLHNDSFSLMEYPNYGGKG
KGTAVLTLTNLGGCLCAMVNHHKDFVLEFADLWVMKEYGKKESWIRLYRICQNQGFDSRM
QIKPIVYSKDKRKVVVEIDNLVFGWYDLESKYLKKIAPNGLPNGNIETSSFVGSLVSVGD
KLQSGGGTLPRRNNKKCYCYRWEFVLNCAVNLLFEVVIGALALTENGAL
>Sgl60933 E3_activity/RING/RING 39.6 5.5
MFFLYESKLCMTTIIFYTCIYIPLLQIKNAICSILGFILFLHDNTLEHPEGLTPVDLVEE
ACSIDLPMSQYSDLKVSGCNTGNLEDGECDEACSVCLVEFMSEDLVSKLSKCGHIFHMEC
IEKWVERNQFTCPLCRSSFLNLDESKCHAICNDMVLSCFST
>Sgl60944 E3_activity/RING/U-box 121.5 0.6
MREKRIPMVPLEPLDAAGIQIPYYFRCPISLELMQDPVTVCTGQTYDRSSIESWVATGNT
TCPVTRAPLSDFCLIPNHTLRRLIQEWCVSNRSFGVERIPTPKQPADPSLIRSLLAQSSS
GSNPIPNRVAALRRLRGLARDSEKNRSLIASLNARDVFVSILFNSDESNSNSFDDSSELN
HEALALLASFPPSDAACASVASDPERVGYLVNLLFHPSSLDVRVNSAAVIESIIAGTKSS
DLRSFICASEQVYVGVISILTNPIPSPRALKIGVKTLFALCLSKQHRHKAVTAGAANALI
TRLTELDKCDCERALATVELLCRVPQGCAAFGAHALTVPLLVKTILKVSDRATEYAAGAL
LSLASSSERLQREAVNAGVLTQLLLLVQSDCTERAKRKAQMLLKLLRDSWPEDSIGNFSD
DFNCSDVVPF
>Sgl60947 E3_activity/RING/RING 29.9 6.7
MKQYSTIHGYSRPVVAAALLRIPPSSLLARAVPFYPQCNCFVYLVYMEYDCEFATEKLRL
PIYGGPRHENNGFVVDRDRFGNLRLNSDELSYEELVSLSEWIGSVTTGLSEETIMALMKR
KSYECVNTNPVPGDDTCCICRVKFFFPTGEYETGEDIGVLNCGHEFHTECIKQWLVIKNN
CPICKLKGLDA
>Sgl60961 E3_activity/RING/RING 14.2 11.2
MEISPASPASYNTQIQSSNSDDKDSNDVVSIEDGEREFSRQNDDFSATSTSSTVVKRSSS
SYDDDDDEEDVCRICRNPGEPDNPLRYPCACSGSIKFVHQDCLLQWLNHSNARQCEVCKH
AFAFSPVYAEDAPVRLPFREFLLGIGKKTCHVLKFFLRLGFVLSVWLLIIPFITFWIWRL
AFVRSFSEASQLFLSHMSFTVILTDCLHGFLLSASIVFIFLGATSLRDYFRHVREAQGHD
LDREDEGDRNGARAVRRPLGQANRNLLADGNADDGGDAQGIAAAGQLIRRAENVAAQWER
QAARLEVHVDQIFDGLDDADGAEDVPFDELVGMQGPVFHLVENAFTVLASNLIFLGVVIF
APFSLXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXAFNIALCVMAFLFCNKPSAVY
SYATYRISSLLG
>Sgl60975 E3_activity/RING/RING 34.7 3.0
MDAEDLELSTISGEGVEVTSYAVEHATSSNNHVHRPVDDLFNVMLCYEDTRIPNNVARYL
SFTMVKERDQSDRTDIVTDVIGKLDEFDVDANVYPSVIDVVQSSCEILLKQVRDLGRRSL
AMIVKIIVFEHVVEEEDLVGIAPDEEEEPEPMMGEEEPMTAEQIARSMAESARKLKRLEG
IVIIVGNDGLDGVKIKRRDQFSTDMGPCSICFEDFEAQENNGGESDDSKHNNTGLLALPC
SHVFHNLCLLPWVYKGKGTCPNCRFNFFKNL
>Sgl61016 E3_activity/RING/RING 15.7 13.5
MDSETLASSSSTAEVPAPDAWITAYQKLLPQWNSYSLLSRLIIPITISRVNQFDAARLDV
EMSAMLKEQLVKVFSLMKPGILFQYEAELDAFLEFFIWRFSIWVDKPTPGNALMNLRYRD
ERVMEVRGKVRTGLEGPGLTAAQKMWYCIATVGGQYIWTRLQSFSAFRRWGDSEQTTLAQ
RAWLLLQHIEGFYKAASFGNLLIFLLTGKYKSLIERVLRARLVYGSPNMNRSVSFEYMNR
QLVWNEFSEMLLLLLPLLNSSSFKNLFRPFSKDKSSDSATDETFCPICQGSPSIPFIALP
CRHRYCYYCLRTRCAATPSFRCVRCSQPVTAIQRLGSSRAETSSKK
>Sgl61055 E3_adaptor/Cullin_RING/DCX/DWD 113.9 17.0
MGIQKIETGHQDTIHDFQMDYYGKRIATASSDHTIKIIGVSNNSQQHLATLSGHQGPVWQ
VSWAHPKFGSILASCSYDGKVIIWKEGNQNEWSQAHVFDDHKSSVNSIAWASHELGLCLA
SGSSDGNIMVYTMRTDGGWDSAKIDQAHPVGVTSVSWAPATAPGALVASGLHDPVQKLCS
GGCDNTVKIWKLNNGIWKMDCFPALQMHTDWVRDVAWAPNLGLPKTTIASASQDGKVIIW
TVARDGDQWEGKVLNDFKTPVWRVSWSLTGNILAVADGNNNVTLWNEAVDGIWQMVTTVD
S
>Sgl61063 E3_activity/RING/RING 32.7 8.9
MGTPLLVSHSETFSDRFPLLMGRLDDCEGCQHVIDIAAVNDAPSSSSNTVSVNQAESHHT
VDRPSSSTQHINSSQSSSSERINSRNSSFGVRGDSYGYTSPLNSGLWISVELVVTLAQIV
ASVVILSLSRYNSTEAPLFAWVVGYASGCLATLPILCWRLRNCSRVPERFLVQSHQSSPG
SVTTAEATASNSSFQQEEVDSHENSRIVSRGSLLRRRISVRLNGIVEHFKMALDCFFAVW
FVVGNVWIFGAHSSPAVAPKLYRLCIVFLTFSCIGYALPFLLCATIFCCLPCIISVMGIR
EDLSKPRGASIETIDALPTYKFKLKKDESINEAQICLKAHKDGILADETQDEFVLSGEDA
LCCICLASYVENDELREMPCSHLFHTECVDKWLKINASCPLCKLEIGEDRSMALSSDQNN
SRRQNASNEGDLSLTPANVS
>Sgl61080 E3_adaptor/Cullin_RING/DCX/DWD 113 18.9
MTLRLNMKRKFAQRSERVKSVDLHPTEPWILASLYSGTVVIWNYQSQTMAKSFEVSELPV
RSAKFISRKQWVVAGADDMFIRVYNFNTMDKVKVFEAHTDYIRCVAVHPSLPYVLSSSDD
MLIKLWDWDKGWVCTQIFEGHSHYVMQVTFNPKDTNTFASASLDRTIKIWNLGSPDPNFT
LDAHVKGVNCVDYFTGGDKPYLITGSDDHTAKVWDYQTKSCVQTLEGHTHNVSAVCFHPE
LPIIITGSEDGTVRIWHSTTYRLENTLNYGLERVWAIGYMKSSRRVVIGYDEGTIMVKMG
REVPVASMDNSGKIIWAKHNEIQTVDIRRVGAGYEVTDGERLPLAVKELGSCDLYPQYLK
HNPNGRFVVVCGDGEYIIYTAVAWRNRSFGSALEFVWSSEGEYAVRESTSKIKIFSKNFQ
EKKSFRPSFSAERIYGGTMLALCSNDFICFYDWADCRFIRRIDVNVKSLYWADSGDLVAI
ASDTSFYILKYNRDAVASFVDSGKPIDDQGVEDAFELLHETSERVRTGLWVGDCFIYNNS
SWRLNYCVGGEVTTMFHLDRPMYLLGYLAGQSRVYLIDKEFNVIGYTLLLSLIEYKTLVM
RGDFDRANELLPTIPKEHHNSVARFLESRNMVAEALEVATDPDFKFELAIQLGRLEVAKE
IATEVQSESKWKQLGELAMSTGKFEMAEECLKYAMDFSGMLLLYSSIGDAEGISTLASLA
KEQGKNNVAFLCLFMLGKLEECLQLLIDSNRIPEAALMARSYLPSKVSEIVALWRKDLSK
VNPKAAESLADPEEYPNLFEDWQIALAVESKVADTRGSYPPAEQYLQYADKLKIDLVEEF
KSMQVEEDQPLENGETEHEEEQEEENGADESQEEDVVVDADSNDGAVLVNVLKIQILSLF
LLNILKVSFNLLVLTVHFVV
>Sgl61128 E3_adaptor/Cullin_RING/SCF/F-box 15.2 0.0
MSIFVRLPEDAILEILLRLPVKSLQRFKCVAKSWYARISDPHFMIRHFISSNNHEFLLVS
HLHPVRRQVLSLLPSETLQNKAKHFQLPYASSSEENRSFVQISGPCNGIFCLFNSKDGAI
SLWNPATRQLKTLPKSNVEPPLTSYPFDICVGFGFDKESNDYKVLAYKHMCFPSSSTIAH
AELYTLSTSTWKEIDVGEEFQATGNLPYSTSYPSVNGIFSWFEIDNHVEKVIFSFDMKNE
VFMKTRLPDYNGIPSKRVHGCLASLKDSLAFIHDYPVGEFSKCFDVWVLGEYSVRESWMK
QLTIGPLLGVTAPLGFWKNGELLLQEEDETKRLVSYDPITKDMKDVQARGVAHILQVIPY
KESLVCFKEDEQESEQNRDDEIPFSVSECQKKTFCIL
>Sgl61130 E3_adaptor/Cullin_RING/SCF/F-box 13.8 0.0
MSTFVTLPEDVITEILLRLPIKSLQRFKCVAKTWYARISDPCFMVKHFISSNNQEFFDCL
LIDQYHPTKLQVLSLLSSEPLQINMKHIQLSYANSIENTLCSTKILGPSNGIFCLFDPPD
CSISLWNPANQQLKTLPVSHIEPPPNAISYQNIVGFGFDNERNDYKVLVYKQMYFPSSSS
TPKIAHAELYTMSTNNWKEIDVGEEFQATNAPLSSPTSVNGMFSWFESDNTLVEMVVFSF
NMTTEVFMKTRLPNIPFKRDYERLASLKESLAYIHTHFVGGIGVMNDVWVLGEYGVQDSW
MKQLSIGPISNLRSVRGFWKNGELLIQTQRHKMVSYDPLTQKAKDVQLRGVFYISEVLPY
NKSPVCFKEDDEQESADHDHKTDVIPLCVTECDEEYLVQTIASYDD
>Sgl61139 E3_adaptor/Cullin_RING/DCX/DWD 129.9 17.4
MNYRFQNLLGAPYRGGNVVVSSNNKLISSVGNRISVTDLIKSETITLPCQSSANVSHIAV
SPDGNFILAVDENSRSQFINLNRRIVLHRITFKGKVSSLQFSPNGQFIAVAVGKLVQIWR
SPGFRKEFFPFELVRTFADFDDGVSCLNWSPDSGYLLAGSRDLTVRLFCLRKLDERKSNK
PFLFLGHRDVIVGAFFGVDKKTGKVLRVYSVSRDGGLFSWGLPEFDVKLGGLGDRDEEMV
DPPSPGTPDKVDEDGGVVGNDVNGNENGKKRKEFDGKAKDFGDESQLLLHKIEWKLLKKD
YFMQAPAKVTACDYHQGLDLVVVGLSSGVFGLYQMPDFVCIHLLSISREKITTAVFNGLG
NWLTFGCAKLGQLLVWEWKSESYILKQQGHYFDVNCLAYSPDSQLLATGADDNKIKVWNV
SSGFCFVTFSEHTNAVTALHFLANNHSLLSASLDGTVRAWDLFRYRNFRTFTTPSSRQFV
SLTADQSGEVICAGTLDSFEIFVWSMKTGRLLDVLSGHEGPVHGLMFSPTNAILASSSWD
KTVRLWDVFEGKGSVETFQHVHDVLTVVYRPDGKQLACSTLDGQINFWDPLDGSLMYSIE
GRRDIAGGRLMTDRRSAANSTSGKYFTSLCYSADGSYILAGGNSKFICMYDIAEQVLLRR
FQLTLNLSLDGVLDILNSKNMTEAGPLNLIDDNNSDTEEGIDKQVRGKLGLDLPGSMPNR
GRPVIRTKCLKISPTGRNFSAATTEGVLVYSVDESIIFDPTDLDIDVTPEAVDAALNEDQ
PSRALVLSLRLNEDSLIKKCILAVNPADIPAVVSSIPFRYLQRSMEALTELLEGCPFLEF
ILRWCQEICKVHGHSIQQNNRNLLPTLRSLQKAITSLHQDLAEMCSSNEYTLRYLCSTSV
RK
>Sgl61177 ULD/UDP/UFD/PB1 57.3 0.1
METPEVSSLDLKETELTLGLPGKTVSNLEEKIVLKRRFSDTLDLNLGSHPNNSNEKKVQQ
PSNAPTNPPKTQLVGWPPVRASRKNVMKSCKYVKVAVDGAPYLRKVDLELYSSYQELLKA
LEDMFSSFTIRNFFNDGKLMDPLNGSDYVPTYEDKDGDWMMVGDTPWKMFVESCKRLRLM
KSSEAVGLEARSSSKVD
>Sgl61179 E3_adaptor/Cullin_RING/DCX/DWD 35.9 9.2
MTPLEVKRQCLLLIIQSLNDEKYKETVHQLERESGLFFNMEYFEELVINGDLDEAEKYLS
GFTSIDDNRHSTKIFFEIRKQKFLEALDRHDEEEAKNILRNELKFVIEHDEKLFEDMTKL
LILTDDRIKKLGSVDADRTNLVGSLKAFIHENIVFRDKLLFPRTSIGRLSELLQQSMYWQ
HLRCTDYTNTPFSSLELETLFTDHTCDQSHDHSLSSNFPVVNPVAEGLMPRPVGQRVTIP
PRPGGIDYCMSFIPEIAIERPLLLSPAIVTMPPEEGLSSRDAAASSSRIQQPITAITNSA
VGGEAAADDLPKIVVAYLSEGSSVSSMAFHPLQHVLLLVGTNMGDVSIWDVGYKKRLVAS
KSKASQTDDNDSINCVSWSLDGALIGVAYSKGILCIYLYRGGAELKDFLQIDAHFGEVRD
LAFSKLTSNLVLTCGDDKTVKIWDCTTGTGLVLEGHEAAVHSLCLLYKKDDLWIQSESIV
STAVDGRIIAWMNSNPNNSYLAPGRSIMRMRSSADELRLFSCGTAKDGQSYLVDEGRRRK
WVFPTLVEFNSSQNEMVDGEPISMEINGLSPYWFDVAQGSAVCNTVNMKSIFLLTGPNGG
GKSSLLRSVCAAALLGICGFMVPAESASIPHFDAIILHMKSYDSPVDGKSSFQIEMSEIR
SLLSATTSRSLVLVDEICRGTETAKGTCIAGSIVETLDAIGCFGIVSTHLHGIFDLPLKR
SKTVNKAMSAEFVNGQTIPTWKLVNGICKESLAFETAQREGVPETLVKRAEELYHSVYEN
KMHVDDVKLDYSGAKTNESNTTEACYSINTSSSIKLATPMETLKKEVHDAVTDICQKKLI
ELYKTTNPSQFPEINCIYIAAREQPPPSTIGASSVYVMIRPDKKLYVGETDDLQGRIQAH
RSKDNMKNAPFLSFVVQGKSVACQLETLLINQLPKQGFHLTNVADGKHRNFGTCESILEP
AIL
>Sgl61215 UBD/ZnF/ZnF_UBP 93.1 7.2
MEEATSAASASTHLTSDLPSNTIVSDESSTMISTQTLSFSSGNPRIEETSGVMHLYSNDL
TSSSSSSPLHLPVGRKPLVCVVGVPNHMTYADFCRFSGSFIQHMLEMRIVRNDEAEDTYI
ALIRFDDQDSTDGFYKHFNGQKFSSLEPEACHVLYIVDVQYTGSIERGQASLLSSTEQPT
CPVCLERLDQDTSGILTTICNHSFHCSCISKWTDSSCPVCRYCQQQPEKSTCIICETSEN
LWICVICGFVGCGRYKEGHAIIHWKETQHCYSLDLETRRVWDYAGDNYVHRLIQSKTDGK
LVELNVPCSHGMHGCGSCECSGDPGINEAVLSSKVEAIVNEYNDLLSTQLENQKLYFEAL
LQEVKEETEKEIAEAVDKAVSLKLQKLQAKLDRCIKEKKFLDDINENLSKNQEIWKAKIQ
EIEEREEKAIRLKDGKIRDLEEQLKDLMLDLEAGQAVEQQSLSDEVKSGSVLKIGGESST
SGASKSKNRKKR
>Sgl61219 E3_adaptor/Cullin_RING/SCF/F-box 16 0.0
MGGIFSLKSSGDRNCQNYEGTASGCKRQRVTTCFEHTTRLVPSLPNEISLQILARVPRVY
YLQLKLVSRSWKEALSTSEIYKLRREFKMTEEWLFILSRVEENLLWCALDPVSQKWQKLP
PMPHDSAHDESKRGLALVQMWNALGSRGKIADAIRGWLGGGDPLDEIPFCGCSIGAVNGC
LYVVGGLSKTSALSCVWRYDPILNSWNEVSPMLYGRAYSKTGVINNKLYVVGGVSRHRGG
LTPLQSAEVFDPETEQWSEVPSMPFSKAQIMPTAFLADLLKPIATGLTAYKGKLYVPQSL
YCWPFFVDAGGEIYDPETNSWNEMPIGMGEGWPAKQAGTKLSVVVDEELYALDLSGSLDN
AKVKVYDHRDDSWKIVSAEVPMTHDQADAESPYLLAAFRGKLHVIIKDGNSDITVLQATA
GSLAQPSQSNQSSSRSSSSGGSVTSSPPAVTWNVIASTRAGPAELVSCQILRI
>Sgl61220 E3_adaptor/Cullin_RING/SCF/F-box 15.9 0.0
MKLRLRSLETKQTQNIEVPNNCNLQQLKQIIILQLFSSSSTIQQNLTLSLNGKEQLFGSS
PEESIQSIGVTSGDLIYYSQNPFAFSSQIPNFSHVQLENENSREINIINCDKGDNLMNTH
EVESGKSDELNNLDVEIRDLMEGTSNLVDSGDHSDDLGKTQVLELCKDDELIGSSSRIRE
SSDYDEENSTELMEESNDQEVDDESEVEGNCRFSVPSFLKKIFVKEVRDAADNGSDHKLL
VIAVHAVLMESGFVVYDPILRKKADSFRLADEWPSLAFGITLYYTLPEAPTSEGVETVVL
KFQSLGKFMTIYGSLPKKGFRVHRVCLDEPLFVPAFSYIWKKSDYTGSENEIGGSRKLFP
NHEIFEFWKIVKDGLAYPLLIDLCEQMGLVSPPCLMRLPTELKLKILEFLPAIDVARVEC
VCSELRFVASNNDLWKLKYEEEFDCAVASQRECQWKARFSSLWDIRKRRKRVCMPPLRWQ
EPPQFRPLFPGRRNRNRFGPPFIIGGDYDRLPAFGIPQHPGRRILGGIVTLEGLVESESL
IDSLS
>Sgl61316 E3_adaptor/Cullin_RING/SCF/SKP1 112.4 1.0
MASAPKKITLKSSDNEEFEVDEVVALESQTIKHMIEDDCADNAIPLPNVTGKILSKVIEY
CKKHVDAAAAKSSSEDRSSSNSAADDELKNWDTEFVKVDQNTLFDLILAANYLNIKSLLD
LTCQTVADMIKGKTPEEIRKTFNIKNDFTPEEEEEVRRENQWAFE
>Sgl61327 E2/UBC 87.2 0.0
METDQNGALNVVEGATSVSGDSFLSGGVNVEGSSNCNVKNEGNLLTAKLESDKHIYRQDV
VKCKDGSMIGVVTEVAGDSDSESESESGITDDEDEDDKEEEEEGEEVEGERGEGKEEDGE
EKDDDRVRDGEDNESCDDNKSDGNNKRDPLTGDQVRVLWMDDSEKMHHRNELTVVDRGFL
HGDYVASALNPSGQVGLVVDVNIIVDLWSTDGNVVKDVSARELKRVRDIVVGDYVVSGPW
LGRVDDVLDNVNVLFDDGSVCKVARAEPMRLRPIAKNLLEDGHCPYHPGQRVRASSSSVF
KNARWLSGSWKANRLEGTVMKVTVGSVYVHWLASAGFGPNSSTSPPEEQSPKNLKLLSCF
AHANWQLGDWCLHPAIKWFSSIPLDKGLSNLRLNESVPCASVSDADELLPEESNVHVELM
DHDAASTSESVDGNGKNNASPESSSCGSSLSISKDTVHESWNNHRKKLRKVVVKRDKKAR
KKEENFERALLIVNTKTTVDVAWQDGTVQHGVDSTLLIPIESPGDHDFVAEQYVIEKVAD
DGEEVPEIRRVGVVKSVDAKEKTACVKWLKQVARPEEPREFEKEEVVSVYELEGHHDYDY
CYGDVVVRLSPVSIMEALAFSDPKVSNVPNGGKGESETNYNDKEGEASDEVASNELSNLS
WVGNITGLKNGDIEVTWADGMVSTVGPQAVYVVGRDDDDSMVAGSEISDDAASWETVEDD
EMDSLENTKKESPPEGTEAHPDSVEDIVVTEHDPGNNGPLFAAIGYVTRFASGIFSRGRK
DGDSFDSEDSVGTRMQPEGEIVLSNERTSSNVDNSLDICANDTGSRQINLDKSDEPAEVE
AAKCSQMADVLGHLNHKESNPSLCADDNICSFKRFDTAKDPVDHFFLGANTPSNSGRKWL
KKVQRDWNILQNNLPDGIYVRVYEDRMDLLRAVIVGAYGTPYQDGLFFFDFHLPPEYPDV
PPSAHYHSGGWRINPNLYEEGKVCLSLLNTWTGRGNEVWDPQSSSILQVLVSLQGLVLNS
KPYFNEAGYDKQVGTAEGEKNSLSYNENAFLLSCKTVMYLVRKPPKDFEDLVKEHFRQRG
CLILKACDAYMKGYLIGSLAKDASVTERIVVAVQESVLYCQFNSATAQVFGSKFRSNYHF
RLTKMCRIEIS
>Sgl61370 E1 369 0.1
MTSQQQLDAIKGARVLMVGAGGIGCELLKTLALSGFQDIHIIDMDTIEVSNLNRQFLFRR
SHVGQSKAKVARDAVLKFRPHIQITAHHANVKSSDFNVDFFKKFNVVMNGLDNLDARRHV
NRICLAAGVPLVESGTTGFLGQVAVHVKDRTECYECYPKPAPKTYPVCTITSTPSKFVHC
IVWAKDLLFTKLFGDKNQENDLNVRSSDGASSSEHIDDVFEHRNGEDIECYGKRIYDHVF
GYNIEQALSNEETWKNRAKPKPLYSRDVLSDKQQNGNRDKTLSSDLASASVSAMATLGLK
NPQDVWNLTENSKVFLETLNLFYSKRSKEIGSLPFDKDDQLAVEFVTAAANIRAASFGIP
LHSLFEAKGIAGNIVHAVATTNAIVAGLIVIEAIKLLSKDDKNLRMTYCNEHPKRKMLLM
PVEPFEPNKACFVCSETPLVLEVNTLRTKLRDFIEKIVRAKLGMNLPMVTLGNSLLYEVG
DDLDDAMIRIYEANLEKVLSELPSPVVSGTVLVVEDLRQELSCKINITQREDFDEEKEPD
GMVLIGWSQAPTDTEKIASVENGESRSGTLVAKPLEIAQVDEAEGNLASKKRKSSEVSNS
SGSHPSSGNDLKNKNKEVIFEDDGDDLIVLDHLSSETAKKKRLV
>Sgl61377 E3_activity/RING/RING 23.1 1.2
MGAACCVASRDRTIQHGSSGEFLHRNFRHSPTWSFRWDNRVGVAGEEPSLGWLSDAASRN
DLMDVKSATDVSAQVSDGGSSLDSYRMGALRKSPVDHELTKSIKTSASGQSVARNASTEV
KQYTESPQPSDSASVKLSPLTHTSSLHMSPISAQSFPPPPSPTPSSWTRGSPAHLQAHQA
SDSHSSGRNSPINSVSEEGQVPFGNSAASNLSTRGSYGRSSDGWSAHGFSEIMSGSQRER
WSFDSDSGSLARDKLSRTSGHNSQSVSVDLQTCGICSKLLAENSAWSSQKIIAGNEQSIV
AVLICGHVYHAECLETITPEINKYDPACPVCTFGEKQTLKLTAKMLKAEKDLKAKNSKKS
RNQVVDTNTSFDFDYWKKSATVYEGKSPKLGNSSSLKISGAKPFLKRHFSFGSRGNKSAS
ESPSIRKKGLFWAKSSRE
>Sgl61422 E3_adaptor/Cullin_RING/DCX/DWD 131.2 31.6
MAAIAATAEEKKEKLSVTELKERHAAAIEQVNSLREQLKQRRRILLDTDVANFAAAQGKT
AVSFGQTDLVCCRTLQGHTGKVYSLDWTPEKNRIVSASQDGRLIVWNALTSQKTHAIKLP
CAWVMTCAFSPTGQSVACGGLDSVCSIFNLNSPTDKDGNLPVSKTLSGHKGYVSCCQYIP
DEDTHLITSSGDQTCILWDTTTGLRTSVFGGEFQSGHTSDVLSLSISKANSKTFVSGSCD
STARLWDTRVASRAVRTFYGHEGDVNAVQFFPDGHRFGTGSDDGTCRLFDIRTGHQLQVY
YQPHGDDDVPQVKTIAFSVSGRLLFAGYSNGACYVWDTLLAKMVLDIKSLQNSHTGRISC
LGLSADGSALCTGSWDTNLKIWAFGGHRRVI
>Sgl61444 E3_adaptor/Cullin_RING/DCX/DWD 118.2 7.8
MGEDEEMPMTEEQLKEEFEVWKKNTPILYDLVLFNPLEWPSLTVQWLPSSPVINSDSSLA
VHQLILGTHTSDHSPNFLMVADVHLPLKNTPCSSIPKVEIVKKFQVDGEVNRAVCMPQKQ
NLVAAKTSGLEVYVFDITKEPSSGVCDPEVRLRGHEKEGYGLSWNPLKEGYLLSGSYDCR
ICLWDVSSMPQSKVLDSMSVFQAHESIVEHVAWHTKNESMFGSVGDDGKLMIWDLRSDKP
QHSVEAHEKEVNYLSFNSFNEWIVATASSDTTIGLFDLRKLTTPLHSLSSHTEEVFQVEW
DPNHETVLASSSDDRRLMVWDLNRVGDEQLEGEAQDGPPELLFSHGGHKAKISDFSWNKN
EPWMISSVADDNTVQVWQMAESICCDEEEIPAE
>Sgl61449 UBD/UBC-like/UBD_UBC 236.9 0.0
MASRRILKELKELERDPPSSCSAGPVAEDMFHWQATIYGPHESPYAGGVFLVNIHFPPDY
PFKPPKVAFKTKVFHPNINSNGSICLDILKEQWSPALTISKVLLSICSLLTDPNPDDPLV
PEFAHLYKTDRNAYESMARSWTQKYAMV
>Sgl61456 E3_activity/HECT 347.1 0.0
METRSRKRAEASSSAPSSSSAGPTTRAAKRTRFSSANTATATPTTRSRSRTNISLSSATA
MDESSSRGGRRGKNHHGSDKDNDKGKEKEHEVEKERERENERGLGLNIDDDDDDDNDNDD
SEGGGGVGLLHQNLTSASSALQGLLRKLGAGLDDLLPSSAMGSASSSSHQNGRLKKILAG
LRADGEDGKQVEALTQLCELLSIGTEDSLSTFSVDSFVPVLVGLLNHESNPDIMLLAARA
ITHLVDVLPSSCAAVVHYGAVNCFCARLLTIEYMDLAEQSLQALKKISQEHPTACLRAGA
LMAVLSYLDFFSTGVQRVALATAANMCKKLPSDAADFVMEAVPHLTNLLQYHDAKVLEHA
SVCLTRIVEAFASFPDKLDELCNHGLVTQAASLISTSNSGGGQASLSTSTYTGLVRLLAT
CASGSTVGAKTLLLLGISGILKDILAGSGLVGNMSVSPALSRPPEQIFEIVNLANELLPP
LPQGTISLPTSSNLFVRGPLFKKSPMSSSSKPDEINGNVQDVSAREKLLNEQPELLQQFG
MDLLPVLIQIHGSSVNGPVRHKCLSVIGKLMFFSNSDMISKLNNSTNISSFLAGVLAWKD
PQVLVPALQIAEILMEKLPETFSKMFVREGVVHAVDSLITAPSTHAATTEKDTESTPGSS
ARARRLRRRSGNQHQDTNSVEESKNTVSVTVGSPPTSVELPTVNSNLRTTVSGCAKSFKD
KYFPSDPGAVDVGVSDDLLHLKNLCAKLNAGVEEQKLKVKGKSKTAGAYIADFSAGKEES
LVGIVSEMLEELSKGDGVSTFEFIGSGVVATLLNYFSCGYFNKEKISEANLPKLRQQALK
RYKLFISVALLTGVDGGDLTPMTVLVQKLQNALSSLERFPVVLSHSARSSGGSARLSSGL
SALSQPFKLRLCRAPGEKALRDYSNTVVLIDPLASLAAVEDFLWPRVQRSESGQKPSTSV
GNSESGPSPTGAGASSPSAFTPATSTRRQSARSRSGLNIGDTSRKESLQDKTNSASKGKG
KAILKPAAEESKGPQTRNAARRRAASDKDAQLKSPTGESSSEDEDLEMSPVDIDDALVIE
DDDDISDDDEDDHDDVLRDDTLPTCMAEKVHDVKLSDSAEDSAAAPATSDSQNNPASGSS
SRAATVRGSDSTDFRSGSSFGSRGAMSFAAAAMAGLASNGRGIRGGRDRHGRPLGGSSDP
PRLVFSAGGKQLNPNLTIYQAIQRQLVTDEEEDERYNGNDPVASDGSRLWSDIYTITYQK
ADSQVEKSHGTVSSASPSKSTKSGSASSSNVDASSHRSPLDSILQGELPCDMEKNNPTYN
ILSLLRVLEGLNQLAPRLRVQTASDKFSEGMILSLNELSATGSRVPSSEFVNSKLTPKLA
RQIQDALALCSGSLPSWCYQLTKACPFLFPFETRRQFFYSTAFGLSRALYRLQQQQGDGH
GSNEREVRVGRLQRQKVRVSRNRILDSAAKVMEMYSSQKAVLEVEYFGEVGTGLGPTLEF
YTLLSHDLQKVDLGMWRSNNSFDKSSMEIDSDEQTKDGKSEDASRLSSRANTNIVQSPLG
LFPRPWSPNADSSEGGQFSKVIEHFRLLGRVMAKALQDGRLLDLPLSTAFYKHVLGQELD
LHDILSFDPEVGKTLRELQALVCRKQYLESIGGDHPDVIAELCFRGTPIEDLCLDFTLPG
YPDYVLKPGDENVNINNLEEYISLVVDATVKSGIIKQMEAFRAGFNQVFDVTSLQIFSPD
EIDCLLCGRRELWKPDALVDHIKFDHGYTAKSPAITNLLEIMGEFTPEQQRAFCQFVTGA
PRLPPGGLAVLNPKLTIVRKHSSSATAAANGTGPSESADDDLPSVMTCANYLKLPPYSTK
EIMYKKLLYAINEGQGSFDLS
>Sgl61533 E3_activity/RING/RING 40.2 7.3
MEGAMGVVIDCSHEFQRRHPISSPNDRDDVQKSLIVRVNIRYYQHILYPNNGAPLVSTQE
YPCSPLNTFIRSCNPFCSLCMHDFVDFLLGQHFLLSDAVHEFSLLLSEVQSMVHSMVIAN
NERNNDRDHRRSSRPLRRRRFDDEIFCYEVRAKIANQVCTEEEYMGLVASGEVFEPLVSV
GGSATATNRRLVAIEGLETVVDVQGLLIKDDSVCAICLNEFSDEVANNDNKNKEYSTSDD
PTIKEVTTTRDDADDAAAAADDDDDDDDDDNDSNKDDSITEDEKLIVRLPCKHVFHKGCI
NKWVQKNDSCPYCRFRLPVLLVDQ
>Sgl61576 DUB/USP 338 6.6
MGAAGSKLEKALGDHFPEGERYFGLENFGNTCYCNSVLQALYFCVPFREKLLEYYEKNKN
PVDPEENLLTCLADLFTQISSQKKKTGVIAPKRFVQRVRKENELFRGYMHQDAHEFLNFL
LNELVDILEKESSAAKEGSENSSEKVANGPRNGLANGVKKEPLVTWVHKNFQGLLTNETK
CLRCETVTARDETFFDLSLDIEQNSSITSCLKNFSSTETLNAEDKFFCDKCCSLQEAQKR
MKIKKPPHILVIHLKRFKYIENLGRYKKLSYRVVFPLELKLTNTMEDADSEYSLFAVVVH
VGTGPNHGHYVSLVKSHNHWLFFDDENVDIIDEAAVQTFFGSAQDFSSNSEHGYILFYER
LTSDTS
>Sgl61589 E3_adaptor/Cullin_RING/SCF/F-box 16 0.0
MDSNTASSPSYSSVDGELFDFLNSVELIDEHENDNENIDDIDDGMEVILSSWNNGSSVDD
ERDWGSSMPKELLTKIVEHVQHFEDFETMSQVCSSWRSAACDAIFGRERLNNNQTHTLPW
LLLPKNGADNYHSTCRLYSLSKRERSPTVQALLSIGGGDEPSSIFNTMASNPTSRKAFID
STIKVAVDNGFNGLDLDWEHQKTQQEMDNLAVLLKEWRAAINAQSATEPLLLTAALRFTA
EADTGVPFPAQAIADNLDWVNAMAYDFYASAWAPKPFVTRPHASLRDPNSEVSGSSGISA
WVNAGVPANKLVLGVPFYGYAWTLVDANNNGVLAPSSGNDTSVGNGVPAYREIKEFISRT
GATVKYDSTYVANYCYSGTTWVGYDDTESIKQKVLYAKNSASLRGYFAWNIVHDSDWILS
KTASQTWGPDN
>Sgl61603 E3_adaptor/Cullin_RING/DCX/DWD 84.5 8.3
MATEAEELQQVENSQKRENEPKNALEVEQQERRENEELDPELFSCLLQPISADSDLDYVG
IRRFLLHRKAQSGDRRRIEWRCNGRGYVAYRNYINRPRNWENQLQSQSSSPNQSGRWITS
PGPLSLLYEADSLSSNRDLRGSSQARNSFSSSTSDYDHRSDRSRRTAEPAYSFVGMHCIF
DQCNVAVTVLKFGHLSSDLLAYGAADGSLTVCTVSDPPTVSKQLIGHSKDVTDFDFTANN
QYIASASLDKTVRVWDISKGVCIRVIYGVTSQWCIRFHPVNNNFLSVGNANKEINVYNFS
TGRLIHKQKLDDEVTAMDHDHTGQLLFCGDAQGCIYTVGMNSHTGALSRIHRNRNGSKRK
SPVTVVQYRTFSLLARGPVLLTCTQDGSLAFFSVALEVKGYLTLRCALKLTPRVHRIRAT
FCPLLSLEKGEYIVAGSEDSNVYFYDLTRPRHTCVNKLQGHSSCVIGITWNSGENLLASS
DAGGTVIVWKRAKIS
>Sgl61605 E3_activity/RING/PHD 37.9 7.4
MGKPRAPKRTLDSVTIKPLNKAIKSGDCVLMRPAEPSSPSYVARVERIESDARGTNVRVH
VRWYYRPEESMGGRRQFHGSKELFLSDHFDVQSADTIEGKCIVHSFKSYTKLDAVGNEDF
FCRFEYNSASGAFTPDRVAVYCKCEMPYNPDDLMVQCEGCSDWFHPACIEMTAEEAKRLD
HFFCQNCSSDDPKKLQNSHAASRLSDTKVDTKRRRR
>Sgl61607 E1 369.5 0.1
MTSQQQLDAIKGARVLMVGAGGIGCELLKTLALSGFQDIHIIDMDTIEVSNLNRQFLFRR
SHVGQSKAKVARDAVLKFRPHIQITAHHANVKSSDFNVDFFKKFNVVMNGLDNLDARRHV
NRICLAAGVPLVESGTTGFLGQVAVHVKDRTECYECYPKPAPKTYPVCTITSTPSKFVHC
IVWAKDLLFTKLFGDKNQENDLNVRSSDGASSSEHIDDVFEHRNGEDIECYGKRIYDHVF
GYNIEQALSNEETWKNRAKPKPLYSRDVLSDKQQNGNRDKTLSSDLASASVSAMATLGLK
NPQDVWNLTENSKIFLETLNLFYSKRSKEIGSLPFDKDDQLAVEFVTAAANIRAASFGIP
LHSLFEAKGIAGNIVHAVATTNAIVAGLIVIEAIKLLSKDDKNLRMTYCNEHPKRKMLLM
PVEPFEPNKACFVCSETPLVLEVNTLRTKLRDFIEKIVRAKLGMNLPMVTLGNSLLYEVG
DDLDDAMIRIYEANLEKVLSELPSPVVSGTVLVVEDLRQELSCKINITQREDFDEEKEPD
GMVLIGWSQAPADAEKIASVENGESTSGTLVAKPLEIAQVDEAEGNLASKKRKSSEVSNS
SGSHPSSGNDLKNKNKEVIFEDDGDDLIVLDHLSSETAKKKRLV
>Sgl61613 E3_activity/RING/RING 23.1 1.2
MGAACCVASRDRTIQHGSSGEFLHRNFRHSPTWSFRWDNRVGVAGEEPSLGWLSDAASRN
DLMDVKSATDVSAQVSDGGSSLDSYRMGALRKSPVDHELTKSIKTSASGQSVARNASTEV
KQYTESPQPSDSASVKLSPLTHTSSLHMSPISAQSFPPPPSPTPSSWTRGSPAHLQAHQA
SDSHSSGRNSPINSVSEEGQVPFGNSAASNLSTRGSYGRSSDGWSAHGFSEIMSGSQRER
WSFDSDSGSLARDKLSRTSGHNSQSVSVDLQTCGICSKLLAENSAWSSQKIIAGNEQSIV
AVLICGHVYHAECLETITPEINKYDPACPVCTFGEKQTLKLTAKMLKAEKDLKAKNSKKS
RNQVVDTNTSFDFDYWKKSATVNEGKSPKLGNSSSLKISGAKPFLKRHFSFGSRGNKSAS
ESPSIRKKGLFWAKSSRE
>Sgl61657 E3_adaptor/Cullin_RING/DCX/DWD 131.4 30.6
MAAIAATAEEKKEKLSVTELKERHAAAIEQVNSLREQLKQRRRILLDTDVANFAAAQGKT
AVSFGQTDLVCCRTLQGHTGKVYSLDWTPEKNRIVSASQDGRLIVWNALTSQKTHAIKLP
CAWVMTCAFSPTGQSVACGGLDSVCSIFNLNSPTDKDGNLPVSKTLSGHKGYVSCCQYIP
DEDTHLITSSGDQTCILWDTTTGLRTSVFGGEFQSGHTSDVLSLSISKANSKTFVSGSCD
STARLWDTRVASRAVRTFYGHEGDVNAVQFFPDGYRFGTGSDDGTCRLFDIRTGHQLQVY
YQPHGDDDVPQVKTIAFSVSGRLLFAGYSNGACYVWDTLLAKMVLDIKSLQNSHTGRISC
LGLSADGSALCTGSWDTNLKIWAFGGHRRVI
>Sgl61838 E3_activity/RING/RING 33.9 5.4
MAGRLRLLSTVNTSVSAGDAGLTSSQSDYVVILAALFCALICAIGLAIAARCVCLHHPLN
LFMTAPIPHTSAPPPGLNKKTLELLPTTKYICEAGTSNKQSDCSICLTEFADGDIMRILP
RCGHVFHVACVDTWLGSHSSCPSCRQLVLVVGQCHRCGGYSAQQGIHGTEVHMRETNTMC
RQDYVRAFLP
>Sgl61886 E3_adaptor/Cullin_RING/DCX/DWD 62.2 20.1
MSSLSRELVFLILQFLDEEKFKETVHKLEQESGFFFNMKYFEDEVHNGNWDEVEKYLSGF
TKVDDNRYSMKIFFEIRKQKYLEALDKHDRSKAVDILVKDLKVFASFNEELFKEITQLLT
LENFRENEQLSKYGDTKSARAIMLVELKKLIEANPLFRDKLQFPNLKNSRLRTLINQSLN
WQHQLCKNPRPNPDIKTLFVDHSCGQPNGARAPSPANNPLLGSLPKAGGFPPLGAHGPFQ
PTPAAVPAPLAGWMSNPATVSHPAVSGGPIGLGAPSIPAALKHPRTPPTNSSMDYPSGDS
DHAAKRTRPIGLSDEVNLPVNVLPVSFPGHGHNQAFNVPDDLPKTVVRTFTQGSSPMSMD
FHPVEPTLLLVGTNVGDIALWEVGSRERIVLRNFKVWDLTTCSMPLQASLVKDPAVSVNR
VIWNPDGTLFGVAYSRHIVQIYSYHGGEDIRQHLEIDAHVGGVNDIAFSTPNKQLCVITC
GDDKTIKVWDAASGTKQYTFEGHEAPVYSVCPHYKESIQFIFSTAVDGKIKAWLYDNLGS
RVDYDAPGRWCTTMAYSQDGTRLFSCGTSKDGESHIVEWNESEGAVKRTYQGFRKRSLGV
VQFDTTKNRYLAAGDDFSIKFWDMDNVQLLTSIDADGGLPASPRIRFNKHGALLAVSASD
NGIKILANSDGLRLLRTYEMSYDSSRASESLTKPLINPISANPISGNVNAAAAAAAAAAT
SSGLPDRSAPMVGMSGMNGDARSLGDVKSRILEETNDKSKIWKLSEISEPAQCRSLRLPE
HMRTAKISRLIYTNSGNAILALTSNAIHLLWKWQRNERNSSGKASANVPPQLWQPASGIL
MTNDVSDASSEEAVPCFALSKNDSYVMSASGGKISLFNMMTFKTMTVFMPPPPAATFLAF
HPQDNNIIAIGMDDSTIQIYNVRVDEVKSKLKGHSKRITGLAFSHSLNVLVSSGADAQIC
VWSSDNWEKQRSKFLQLPAGRAPTAQSDTRVQFHQDQTHFLVVHETQLAIFETKQLECVK
QWVPRESSAPISHAAFSCDSQLIYASFLDATVCVFSAANLRLRCRINPSAYLPANVSSSN
VHPLVIAAHPQEANQFAVGLSDGGVHAVCQLRLQWALQALINNKDDPMVSCFALLACFLS
RCRLWLCIYSSSIVQLRYMYLLKFV
>Sgl61918 E3_adaptor/Cullin_RING/DCX/DWD 39.5 13.0
MTTPSEVNRQTLISVLACLKNENYKETVHQLERESGIFFDMEYFEELVINGDLDEAEKYL
SGFTSIDDNPYSSTIFFQIRQQKFVEALLRIEKKKAIDILTNELKFIIEHNKKIFEDLMM
LSTLEDIKEVLKLIGYVDIKTARTNLFGFLKKSIHQNVAFQDKLHFPKSSIRLKELLSQS
MQDDRSMPSYICGQPHDQSAPFPLSHLPRFIEAASSSIQLPITTIANSAVGDQAAADDLP
EKLVAILSEGSSVSCMAFHPLQHNLIFVGTCTGDVSIWDVDSKQRLVYRKFMAWHLLPKS
LQSASQADDTVSVSCVSWSQDGAHIGVGYSKRVSQIYLNSGGTELNNNLKIDAHDGCVRD
IAFSKLPHRVIVVTCGDDNTVKVWHCAPNPNIPEKVLKGHTAAVHSVCLDYIIEENGGLS
ESIISTDVDGRIIQWLNAELNTSYLSPGLSTMRMRFSANGLRLFSCGTNKGGQSYLVEWE
YCKGLKGDRPKGEYQGLGKSVSVVSFDIALSKYLAVGDESVIKFWHMDHSNILATIDVGG
LPASPCIRFNKEGTLLAVSTADNAVQVLANTEWYEARSSSLRLQRY
>Sgl61919 E3_adaptor/Cullin_RING/DCX/DWD 47.1 9.5
MTPLEVKRQCLLLIIQSLNDEKYKETVHQLERESGLFFNMEYFEELVINGDLDEAEKYLS
GFTSIDDNRHSTKIFFEIRKQKFLEALDRHDEEEAKNILRNELKFVIEHDEKLFEDMTKL
LILTDDRIKKLGSVDADRTNLVGSLKAFIHENIVFRDKLLFPRTSIGRLSELLQQSMYWQ
HLRCTDYTNTPFSSLELETLFTDHTCDQSHDHSLSSNFPVVNPVAEGLMPRPVGQRVTIP
PRPGGIDYCMSFIPEIAIERPFLLSPAIVTMPPEEGLSSRDAAASSSRIQQPITAITNSA
VGGEAAADDLPKIVVAYLSEGSSVSSMAFHPLQHVLLLVGTNVGDVSIWDVGYKKRLVAS
KSKASQTDDNDSINCVSWSLDGALIGVAYSKGILRIYLYRGGAELKDFLQIDAHFGEVRD
LAFSKLTSNLVLTCGDDKTVKIWDCTTGTGLVLEGHEAAVHSLCLLYKKDDLCIQSESIV
STAVDGRIIAWMNSNPNNSYLAPGRSIMRMRSSADELRLFSCGTAKDGQSYLVEWEDHKS
GCLKREYWGLGKSASVVEFDTTRNKYLAVGDESVIKFWHMDHSDLLETVDVGGLLESPCI
RFNEEGTLLAVSTIDNAIKVLANADGMDLVRFKETLSLRL
>Sgl61984 E3_adaptor/Cullin_RING/DCX/DWD 24.7 0.0
MYLYSLTLQKPTGIICAINGNFSGGKVQEIIVARGKVLDLLRPDDSGKIQTLLSVDIFGA
IRSLAQFRLTGSHKDYIVVGSDSGRIVILEYNKEKNVFDKVHQETFGKSGCRRIVPGQYL
GIDPKGRAVMIGACEKQKLVYVLNRDTAARLTISSPLEAHKSHTITYSICGVDCGFDNPI
FAAIEMDYSEADQDSTGQAAAEAQKHLTFYELDLGLNHVSRKWSEPVDNGANMLVTVPGG
GDGPSGVLVCAENFVIYKNQGHPDVRALIPRRADLPAERGVLIVSAATHKQKSMFFFLLQ
TEYGDIFKVTLDHGNEGVSELKLKYFDTIPVSSSMCVLKSGFLFAASEFGNHALYQFQAI
GDDPDVESSSAQMMELETDEGFQPVFFQPRRLKNLLRVDQVQSLMPIMDMKVINLFEEET
PQIFSLCGQGPRSSLRILRPGLGITEMATSPLPGVPNAVWTVKKNVNDEFDAYIVVSFAS
VTLVLSIGETVEEVSDSGFLDTTPSLAVSLVGDDSLMQVHPSGIRHIREDGRINEWRTPG
KRTIVKVGYNRLQVVIALSGGELIYFEVDMTGQLMEVEKHEMPGDVACLDIAPVPEGRQR
SRFLAVGSYDNTIRILSLDPDDCMQVLSLQSVFSPPESLLFLEIQASTGGEDGADHPASL
FLNAGLQNGVLFRTVVDMVTGQLSDSRSRFLGLRAPKLFSIIVRGRRAMLCLSSRPWLGY
IYQGHFLLTPLTCGTLEFAASFSSDQCAEGVVAVAAEALKVFTVERLGETFNETAIPLRY
TPRKFVLQPKKKLLVMIESDQRAFTAEEREAAQKECFGAAVDENGNIEMENGDEDEDNQL
SDEQYGYPKAEKEKWVSCIRVLDPRTEETTCCLELQDNEAAFSICTVNFHDKEYGTLLAV
GTAKSLQFFPRRSYDAAYIHIYRFVEGGKLELLHKTQVDGVPLALAQFQGRLLAGIGPVL
RLYDLGKKRLLRKCENKLFPNTILTIHTYRDRIYVGDIQESFHYCKYRRDENQLYIFSDD
VYPRWLTAAHHVDFDTMAGADKFGNVYFVRLPQDVSDEIEEDPTGGKIKWEQGRLNGAPN
KVEEIVQFHVGDVVSSLQKASLIPGGGECIIYGTVMGSLGAFLPFTSRDDVDFFSHLEMH
LRQEHPPLCGRDHMAYRSAYFPVKDVIDGDLCEQFPTLPMDMQRKIADELDRTPAEILKK
LEEIRNKII
>Sgl62012 UBD/Alpha-Helix/UBA 19.7 0.8
MNLRLRLLLSKQSLTNFRRFTTSSSSAIVAPYNKQNRFHNHSKSPLPKTPSFQNTQKTNF
HSSHQLNQSQSTAMIVADDDEEDEDVAALNEFLSRFVHIMRGNLNETYPQCDKPTIDAML
KVIVEKLVSEMEKGGNLEERLVSNGGDGDFSDDLWKTVLEVSNNVYQEMEREKKKEKLKM
FLQCDEVKGLARFASEVGVRGDMLHELRFKWAREAMEKAEFYEKLESIGEAAVAKAEAEA
EAEAEKESNAGGDDSGGLPKRHGKIKYKLYGLDLSGSQWKEVADRIHDAGEVIWEKEAKA
ITGKCKLVNEKIIGLSESQFDSEISPLLDEWKELLQPNKVDWMLLLEKCKEKDSSLYLKM
AERVLDEPSFQATTTDYSMLVEVHAKADRLEDVDRILKKMSDRGVPRDILTLKALLHMYS
KTKNLEQAKAVYEELNSQGFKLDMELYKSMIMVYVNAGNPKLGEKLMREMDVRDIKPTEE
IFMALMRAFAKRGDIIGAQRVVTTMQFAGFPQTAESCACLIEACAKSNYPDDARRYFREM
MNLGFKPDDKCTSLMISAYEKNNKLEVALHLLLELEKGGFEPGVLTYSVLIDWLGKLKLV
DEAEQMLAKMAQLGEVPPFKLQLSLCEMYAGAGNEKKTLQALGVLEAKKDLLDHQDFERI
IMALLNSGLVQGAQRMQTMMEAQGFTPSEGLKIKLMSIQAFSGNTGIGSTRPRMR
>Sgl62060 E3_adaptor/Cullin_RING/DCX/DWD 109.3 6.1
MNKMSLINEFQVEFTQRSSRVKSLDLHPVQPWVLVSLYSGTIQIWNYNSKNMEKSFEVSS
NVPVRSAKFVAQKDWIITGSDDKMIRVYNYKSEEKLKEFVAHEDFIRHIVVHPTLPCVLS
ASDDHHIKVWDWEKDWTCTRIFEGHSHYVMQLAINPRDHNNFASVSLDGSIKIWNLENSN
PSASLAADAHAKGLNCVKYYITSEDKLYLLTGSDDFTTKVWNYESLSCVKVLEGHTGNVT
AIVVHPNLPLIITGSEDRTIHIWNAINFNLEKTLDHGLGRVWVMEIEKNSNQVFIGYDEG
HLMGNIDGSHGTHSAKLKIN
>Sgl62139 E3_adaptor/Cullin_RING/DCX/DWD 24.8 0.0
MYLYSLTLQKPTGIICAINGNFSGGKVQEIIVARGKVLDLLRPDDSGKIQTLLSVDIFGA
IRSLAQFRLTGSHKDYIVVGSDSGRIVILEYNKEKNVFDKVHQETFGKSGCRRIVPGQYL
GIDPKGRAVMIGACEKQKLVYVLNRDTAARLTISSPLEAHKSHTITYSICGVDCGFDNPI
FAAIEMDYSEADQDSTGQAAAEAQKHLTFYELDLGLNHVSRKWSEPVDNGANMLVTVPGG
GDGPSGVLVCAENFVIYKNQGHRDVRALIPRRVDLPAERGVLIVSAATHKQKSMFFFLLQ
TEYGDIFKVTLDHGNDGVSELKLKYFDTIPVSSSMCVLKSGFLFAASEFGNHALYQFQAI
GDDPDVESSSAQMMELETDEGFQPVFFQPRRLKNLLRVDQVQSLMPIMDMKVINLFEEET
PQIFSLCGQGPRSSLRILRPGLGITEMATSPLPGVPNAVWTVKKNVNDEFDAYIVVSFAS
VTLVLSIGETVEEVSDSGFLDTTPSLAVSLVGDDSLMQVHPSGIRHIREDGRINEWRTPG
KRTIVKVGYNRLQVVIALSGGELIYFEVDMTGQLMEVEKHEMPGDVACLDIAPVPEGRQR
SRFLAVGSYDNTIRILSLDPDDCMQVLSLQSVFSPPESLLFLEIQASTGGEDGADHPASL
FLNAGLQNGVLFRTVVDMVTGQLSDSRSRFLGLRAPKLFSIIVRGRRAMLCLSSRPWLGY
IYQGHFLLTPLTCGTLEFAASFSSDQCAEGVVAVAAEALKVFTVERLGETFNETAIPLRY
TPRKFVLQPKKKLLVMIESDQRAFTAEEREAAQKECFGAAVDENGNIEMENGDEDEDNQL
SDEQYGYPKAEKEKWVSCIRVLDPRTEETTCCLELQDNEAAFSICTVNFHDKEYGTLLAV
GTAKSLQFFPRRSYDAAYIHIYRFVEGGKLELLHKTQVDGVPLALAQFQGRLLAGIGPVL
RLYDLGKKRLLRKCENKLFPNTILTIHTYRDRIYVGDIQESFHYCKYRRDENQLYIFSDD
VYPRWLTAAHHVDFDTMAGADKFGNVYFVRLPQDVSDEIEEDPTGGKIKWEQGRLNGAPN
KVEEIVQFHVGDVVSSLQKASLIPGGGECIIYGTVMGSLGAFLPFTSRDDVDFFSHLEMH
LRQEHPPLCGRDHMAYRSAYFPVKDVIDGDLCEQFPTLPMDMQRKIADELDRTPAEILKK
LEEIRNKII
>Sgl62251 E3_adaptor/Cullin_RING/DCX/DWD 97.7 6.5
MEYKLSPSDKKNTLSKFFKEEEKQSSPSFHHLSLVQHLQDNLSSAYGTHLLSEPGSPLLP
QSPESLWSHSPLQSPSHPSLLYCCISSLHREGDIYSIAVSGDHLVLTGSSSRRVHAWQAE
DCHAKGYIQASTGQVRAMVAHGEILFTSHKDHKIRIWNIRNCNGSNNNFSPKKITTLPSS
NNHYFKNFISRPLIAPPLKPIITPLHKDTISCMAYYHIEGILYTGSFDKSVKVWRINEKR
CVDSFIAHAGNVNDMVVNQQNGYLFTCSSDGTVKMWLRVYGENTHALIKVFTFHTYPVYA
LALSVSMSQESVLYAGSSDGCINFWEQQLSCRYTHGGILQGHRFAVLCLVTLEKLLISGS
EDSTIRIWRREKGKHECLAVLEGHRGPVRCLNAVLQKDSFAVSFLVYSASLDQTFKVWRV
KLLPSEIKNDYSNKKSSLKDDDDHVIDTTTTTIDHHHHHTSPVLSPSWVKKKLQCRNLKK
>Sgl62263 E3_activity/RING/RING 23.8 12.6
MEPIYPIAPPPPPDHHHQRHESTTRLQPTQAFADRILRAIGHRLLLLYRSDPNFYVLGAT
GNVYVVNVSTTLACSCPDRATPCKHILFVLIKVLGVPLDEPCLRKRTLRPSHLAQILANP
SLPDSFASPTLCQRFYQAYFLQRDQGEAAQSSSATVVEDGVMCPICLDEMGKSGKKLVAC
GTCRNCIHEECLMAWKRTQRRRTFSCVICRSRWKDMVEQERYLNLAAYVNEDDHMGPQPA
GSTTCHE
>Sgl62317 E3_adaptor/Cullin_RING/SCF/F-box 14.2 0.0
MATEEDESYNQIIPAMIPHWRKPIEGRLPPDSLIQIWARLPIKSLYKFRSVCKLWNALIS
SDPLLSDLLPDRPIRLSTRPFEEIIRDDRDPNTHPIRNGFTPYVDFSLNFVPSNGPIVCV
AADQYFYLCNPSTQEFLRVSPGQNGNSKTSNGGFGYLGDVNQYVLVALFGEKCELLEFGP
GQAGLGLWREVQQRCPCRVTGFGLMVDQGFYWKVSDGSGFVVCLEVKSEEFKLISPPQGN
ENEEILYNQLYLVEFKGCLCAVDNFSRPPRMEIWVLNRFEGEFGWVRKYNIFISGMSRDV
VYPFCDYEGENGGEMMLCNDTRSRLYRYNLKNRSIKQVFRLKNRTGDRLALYSPGLFPLS
FAS
>Sgl62323 ULD/UDP/UBQ/UBQ_Other 24.8 0.1
MGRLSFKVANNDDDDIFGVGRDGLYLSRVSISSKNRRSFCRSSSSISTALSIVNSRKSFS
YDKLAQAPIHLSVVKLDGSRFAIEVIKMATVSDLKQAVESAFSHLPTKGPGKVSWRHVWT
QFCLSYCGQKLLNDNEHIKNYGVKDGDELRFVRHVSIAYNLIKKRSSKRIEAPKPNSVAE
NGEEESNKVEEASADDLENARNQIEVKTNHNESKVPLSNNGWVQYSRLSSTEQLKFEKQA
NQSRWAGGFIGSLRSLFHFCDKRHPIYSSRVSQVEI
>Sgl62347 E3_adaptor/Cullin_RING/DCX/DWD 87.2 18.8
MKALNEELVFLILQFCREEQLNETVHVLERETAVFFDLNYFETLILSGNWDKVERYISGY
GSLKDDKLLSKVHFEVMKQKLLEALDIGNHAKALEIVRNELNVFASYEEELVKEIAQLKS
FDDFREHKLLRNYGDIHSARSCLFKELRKIIQGHPGFQKKLDLNWQHLRCQSPEAIPEIE
TLYEDHMCQPNDQFIESIIEPAYPVYPETTAVSSATDSDGSETELSTDSQEEVRPYHSPE
SEFIDLSVTIGCVLNEESSPTTMDFHPSDNSILLVGTDDGGVSLWDIALRRRLLSRNFKV
WYVGECTSKFKEAFTNNPHVSAKCTRWSSRGDLIGVAFSKQIVQIYTYEADNGMLESLEI
DAHDGSVNDISFSKPNDETFAITCGDDKMVKVWNASTGAKRYVFDGHKAAVICACPTVIK
GVNLIFSTSETGEMRGWMYDNLKYRVAVDDPCRRRMVCSKDGKRIFSCGINEEAQSCILE
WDTESNNVKQTYQGLKKPCPGVVHFDTAKNQILAAGDDHQIKFWDMRNLELISSTDTGES
LPVYPYIRFNKDGSLLAVSASDNKIVIMATAYGLEFLTSCQEHHSVVCVRDDDNLLEVAC
NSISEDNNSHEPLLLDTDPGLHIRWLSSDVKDGKICRMAYSHSGNSILALTWGGTLLVWR
WSGSDTNSMDIDGAVGTMPQLWKPENSSSVMLNIHGPQPDLVVPCFALTKNDAYLISGSG
GELSLLDILAFKRLLTFIPPLPQTTAVAIYPKDNNVIAIGGSDSTILIYDIPFGEIKSKL
EGHSRKIIDLAFSTVLDILISSGADSKICVWDTERWEMKASMYLDGLTEARIQFHQDQVH
FLVIHDTALAIYEAQKLQCRNQWFIGENCSPISCAAFSCNGNMIYVGFCDATLSIFDASS
FQLRSRTRFQFSSVDIHPMAIAVHPKKAYQFALGLSDGTAAIFELSEPNCRSTIPPKESP
LMACYDSSESQLPSLNPTLVGPDSSPTDTCKLHIPESQLPSLNPNSL
>Sgl62362 E3_activity/RING/PHD 37.8 5.0
MTSFLDEFQANLELLPNILQKKYALLRDLDKSLQDILRQNEQRCEQEIDDIKQAMLSSST
RPDPSRIRFSDEALDEQKHSIRIADEKVALALQAYDLVDTHIQQLDQYLKTSEEENRREK
ELASTSASPDDGSTKNGRGSEGGRGGRKKTRLAAAAAAAAATVPVNPPSMDLDVPVDPNE
PTYCLCNQVSYGEMVACDNPDCRIEWFHFGCVGLKEKPKGKWYCSDCASTHKRRKGK
>Sgl62408 E3_activity/RING/RING 40.7 9.9
MVEGMGEIVVTVTGYCGTERMKSGANSFGKMSKSVTHLVCWKFEREKYRFAKNYGIRIIN
HQWVDDCIKEGKRVPEFPYTQKSGQKVGFHISNIPAALETAGMLSENWKLLNKPSIHDYL
DEMNLHSVEIRNTDWDNNPLLDEYPTKQRRSNTDRSIEMGSDYAEPSHRNRRLVKKNAEQ
QSKKNEDGIQVNGCTVSTSTSDDIIDLSTEIEPSISRRVENASAAHGESTDEINYVTDLD
PLLDTSLYGDNALNVEGRNVKETSPGEKLNEDKCNKDQSAVGVSVDLSCVICWTEFSPIR
GVLPCGHRFCFSCIQSWSQHMASSRKESRCPLCKETFASITKVDATASSDQKIYS
>Sgl62409 E3_activity/RING/RING 40.2 9.9
MVEGMGEIVVTVTGYCGTERMKLIKLINYSGANYVGKMSKSVTHLVCWKFEGEKYRFAKN
YGIRIVNHQWVDDCVKEGKRVPEFPYTQKGKLLNKPSIHDYLDEMNLHSVEIRNTDWDNN
PLLDENLSPSLSRRETARQRSKKKLVKETSREDRRGKAVTKRANELQCEVSDYLPKYPTK
QRRSNTDRSIEMGSDYAEPSHRNRRLVKKNAEQQSKKNKDGIQVNGCTVSSSTSDDIIDL
STEIEPSISRRVENASAAHGESTDEINYVTDLDPLLDTSLYGDNALNVEGRNVKETSPGE
KLNEDKCNKDQSAVGVSVDLSCVICWTEFSPIRGVLPCGHRFCFSCIQSWSQHMASSRKE
SRCPLCKETFASITKVDATASSDQKIYSQTIPCPSSAQDLFIVPEGRSYLSNFEMAPPSV
CCNCQRGDPVEFLEYCQFCLSSCIHYYCLDPPLFPWTCIHCRERRLPFRN
>Sgl62420 E3_adaptor/Cullin_RING/SCF/F-box 12.1 0.1
MVEKTAIVNQSSRRHDYIPFELWIEILSKLPLKSLVICKAVSKEWKSIVVFLIKKSDVVP
ICGLFLRVHNTVEGRILRRIIRLILNNDNNNNNNNDNHINMLAYTCLKTRKAINIQKNTR
VINNSGYDRGILSNLCFDVGALLKYNVLNPSTWLFGGLNPGTFFSFHGGLLLVGFYGGTY
EVHNVATKQVVTVPKSPSNAFKYLLMTVIMGILGIRSHHRQDAIVEVPSEKIGHVSYNRL
KVMMKKSMLKGLPQLDVKEDIVCAGCQFGKAHQLPYEESKLKTKEPLELVHSDVFGPIKQ
HSISGLCYMITFIDDFSRYVWVDFMKAKTEAFEKFKLFKGTVEKEVGNKIQCLRTDNGGE
YTSREFSQYLRDCKIRRQLTCPYTPQQNGVAERKNRHLAEICRSMLHAKNVPPRFWVECM
KTATHVTNRLPQARLGFVSPFEILRKMKPTVSHFRVFGCVCYVFVPEHLRSKFDKKAIRC
IFVGYDEQRKGWRCCDPTTDRCHVSRNVVFDEASSWWSPQAVLLPDSKEIEEKLQKKFNE
NNEDQSSQDGGGLEIVRSQPTSAEREKSPWKTGAHHSNFEEERPSQIEDLQEEEEESRPV
LRRSTRQRKPNPRYANAAVVENGTVLSGCQGLCTVSIRGQGYGNVTSPSTSLTMVLVRSG
FGRETVQYIYNFRSWGWIPQLVITNSLQLSTLHLTKKNAQKYVAKAIDAGHRVMPLTCHP
RLPVIFILVKSTIYAYHYHNDCLEEMGQIGDDYENIDHVYPFKPSLNSLPIVVKQDSFFP
SSFSLASFVIHLVERINPRSFILFVTFVCLFIKFVDGTPLSFMIVVLYLFGIVLEWNIAS
YVVGHFEFSRVVLILCVLSSVLVWYYYRT
>Sgl62425 E3_adaptor/Cullin_RING/SCF/F-box 14.5 0.1
MIMAPPKVIKTYENTTKRQKTMKRSSKTRLTNNFTVDDDHYNEVLTSPPIMECLPTEIIS
EVLVRVAVSSPVDLFRCKLSCKAFQEMSEEKNILQQVSLDNLMSRHSWLTDNAKPFFMKC
LANNNPHALIHFGLVQYFSDMMLEEGLKNLEKATEQGNKDAGYVLSLILLCSGDKECIKK
GTDLMLNIMRVIRGKGIVECRKKLRDFMRSMWIVNKFIAKTKPQFPCALKQQHEIRNNWY
KADYYHEEGEDTVVCESCKIVREINFFCQLFGE
>Sgl62435 ULD/UDP/UBQ/UBQ_PIM 51.8 0.2
MQVVIVTNNFTNFSLEITPQEPVLVIKQKIANILGIPVFFQTLSVLGIELINGLDMDDYP
IINEGTRIDLIVSSTDEEMITPPMDDYYTEHTSSHTKIPVTIKFSTREINIEVDMITETV
RSLKEKIHIIDGTPIKRMLLYTSGVEMEDEFRLLSEYAIHEYSEIAVFLRSMNRLKAEPP
CRKLKMVVQTSKSLLNAASIPLEMKDSCTLNEVRQFMLSRRILPMDDYIFIHKQRIMRDN
CTLRWHGVENGDYLYVFKGTISKNGC
>Sgl62537 E3_adaptor/Cullin_RING/BCR/BTB 69.2 0.1
MMANLDAGEVITATTDPKRTETADISSSKSVIETVNGSHRFEIKGYSLAKGMGAGKYISS
DIFSVGGFDWAIYFYPDGKNPEDSSAYVSVFIALASEGTDVRALFELTLVDQTGSKKHKV
HSHFHRALESGPYTLKYKGSMWGYKRFFRRPALEASEYLKDNCLLLECTVGVVKSRMERP
KQYSINLSPSDMGNCFKDLFENEIGCDIVFQVGGEKFHAHKLVLAARSPVFRAQFYGLIG
NPNMETVVVEDIEPSIFKAMLLYIYSDSLPDVHEIMGANSSCSFAIMVQHLLAAADRFGL
DRLRLLCESKLCEKITIETVTTTLSLAEQHRCEQLKTVCLSFAAENLNAVMKSEGFKYLE
ESCPSLLSELLQTIASVDDTSGLPVSKKRSISSVFACDLAGADGGIQAEAANSNGRRMRR
RL
>Sgl62557 E3_activity/RING/RING 32.3 6.8
MSSTTLTTSTTSPTSYWCYRCNRFVRVSPNPLSIVSSISCPDCHGGFLEEIDSHPSTPPP
PLPSQLSSSSLSDSRRRRFPAAAMYMVGNGNSNNLNTTTNTPSLSSSSPRLRRSRRNGGD
RSPFNPVIVLRAPSESDAAPAATGGGVGSGGSYELYYDDGGGSGLRPLPASVSEFLLGSG
FDRLLDQLAQIEINGIGRAEQPPASKAAIESMPTIEIVDEHVEGECYCAVCKDAFELGSE
AREMPCKHIYHHDCILPWLSLRNSCPVCRHELPADNNTTRADSNSIEPNPGTNSNTNLNS
ISSANNHSNGGLVESNEDETVGLTIWRLPGGGFAVGRFSGGRRGERELPVVYTEMDGGFN
QGGVPRRISWGSRGGRSAESGGIRRVFRNLFSCFGGNRNQMLEDSTSSSTDSRANNSQRS
RSTSFFSASSRSRSRGFDMGSRIRR
>Sgl62559 E3_activity/RING/RING 30.8 6.0
MSFVFRGTRADIENAFPGMVPDRGVRIHATRPVNSNSLAFLVTVLLLFMILNSNQMSPNF
LLWLVFGFFAMATALRMYATCQQLQAQAQAHAVAVSGLLRHTELRLRMPPSIAFASRGRL
QGLRLQLALLDREFDDLDYDTLRALDADNAPAVPSMSEEEINSLPVHKYKFTGADCDIAV
KQHPSSSVSPEKQQDISFNVGSSKSSSEDELTCSVCLEQVNVGELIRSLPCLHQYHASCI
DPWLRQQGTCPVCKYKIGVGWPGDGHEDAAYMV
>Sgl62568 E3_adaptor/Cullin_RING/DCX/DWD 89.3 16.6
MELEQRRRSGLNLPSGMSQTSLRLETYRPTTPKTANETTPLRSNLCLSSPRSVSSPRSIT
SLSSATSSPTSKKSICSDRFIPCRSSSRLHTFGLIEKSSPTTNNKNNNNNYNSNSKDGGN
HEAYTRLLKQELFGADFVSSPAGSPMSSPNKNMLRFKTEYSSPNSHYSPSGLGRDSGVSN
EVSTPPKPPRKVPKTPHKVLDAPSLQDDFYLNLVDWSSQNLLAVGLGTCVYLWNASNSKV
TKLCDLGPNDGVCAVQWTKEGSYVSIGTNNGQVQVWDGTQCKRVRTLNGHQTRAGVLAWN
SRTLASGSRDRNILQHDLRVSNDYVSKLVGHKSEVCGLKWSHDDRELASGGNDNQLLVWN
QHSQQPILKLTEHTAAVKAIAWSPHQSNLLASGGGTADRCIRFWNTTNGNQINSIDTGSQ
VCNLAWSKNVNEVVSTHGYSQNQIMVWKYPSLGKVATLTGHSLRVLYLAVSPDGQTIVTG
AGDETLRFWNVFPSVKTPTPVKETGMWSLGRTYIR
>Sgl62617 ULD/UDP/UBQ/UBQ_Other 29.3 0.1
MAAAALRRPLGGDYLSNKKEGNQAVRRRVFVQTETGCVLGIELDGSENVHTVKKKLQLSL
HVPTEETSLTCGDTVLKNDLSIVRNRSPLLLTRNCLHRSSSTPCLSPSTKDLHQKDQSYP
IEVIGCSSHFPVTKQLVNSIVNAMESGIDPVPVRGGLGGAYFFRDINGENVAIIKPTDEE
PFAPNNPKGFVGKALGQPGLKRSVRVGETGFREVAAYLLDYDGFANVPFTALVKVTHRIF
NINHDGVSGNTGHQQREQISKIASFQQFIPHDCDASDHGTSNFPVSAVHRIGILDIRILN
IDRHAGNLLVRKLDDDGVGKFNQVDLVPIDHGFCLPESLEDPYFEWVHWPQASIPFSEDE
LQYIANLDPFHDSEMLRVELPMIHEACLRVLVLCTIFLKEAASFGLYLAQIGDMMSREFR
GQAEEPSKLELICINARSLQKSQMMINSSLEENEDEFQFDLECEVSNGDLSRILEDAVPI
QKNSLEKNGNIGTNYLCKLKETGETKSKTRINGISPGNGSASEQLPISSSFVTLADMNEE
EWTAFLENFQKLLHPAFEKYKSGKVGQRLTQRLGTSCKF
>Sgl62626 E3_activity/RING/RING 36.5 10.6
MLSGYLFAPFSKANKFTIWLFDNYKEGGNCICVNCFLQNFFHMYSSLFRRGEVQSLPSSI
QGASLTSVVSTDNSLADMYRSPPRPLPYDADPRCYRMQRDGLFSRREKGSSHSHDETEPL
RRSDIDSDSDPLSPGDKWNESTCGDDSKEGRKSSAKLSSAKSTTVMGYFYSSSEDEDVCP
TCLEEYTEENPKIVTKCSHHFHLGCIYEWMERSESCPVCGKVMAFDESP
>Sgl62660 E3_activity/RING/RING 21.8 0.7
MEGSRRTDYPVDTIICNLNTITTTGNSSYRVSSQSGWSSSSNDFVSDHTTQGYSGMDSSF
AGRNRSSDMNNVRRANHPLRFRLPSQDQHPRTSRPSVADGSSSSSSSWIGNAARSTGSDT
IQIQFGGRQISATPVHLSPPNFSTYTSSPLQMESLEFGVDDYSTDDELWEPYDYRYEIPM
HSMVIVNNNRNGLDEEDRIAAAMRTQQYNTTTTTTTATTGSTCCICHEDYNDGESIGILK
CSNNHQFHENCIKNFELQRRLMAENADSKSTLLLETPQEQKQHNSIPEHLMCKNRLQEFC
QRARIPFPVYYTFCEGGPQHAPKYKSTVEVDGEKYTCHNSFSNRKAAEQDVSKIALEGIT
EKFKNCVSKKTTEGGFPPVFQDKVFCKSILHEFAKKMNIDLPKYDTVKVEGAYPIFTSSL
VFDGVKYSGQPGVNKKDAEQLAARAAILSILAKPGQGMQLSEIVKSKAKLFSVVHEHTSA
GDSPSQPISGNPHETSVTRDSVGTNQASEVIGNVVSEELQGQAHVPSKHTGVGDSTLQPI
AGSPHKTSATGYSVGANQASEVIGNVVSEELQGQAHVPFKHTSAGDSTLQPIAGSPHKTS
AIGDSVGANQASELIGNVVFEEHKGQAHVPFKHTCAGDSPLQPIAGSPHKISATGDSIGA
NQASEVIENVVSEVHHGQSHVLPKHEFRKPGLDTYTPVVPLPIAFVPSAEVQIPLDASAC
GKKRKSRKKKKANKKAKTVP
>Sgl62746 E3_adaptor/Cullin_RING/BCR/BTB 41.3 0.0
MDQGFANVIKWVKEMKDMEEEVNDKLRFIGEFEVAFRDEIHTDILVKPGNNGPPIPAHRA
LLAAKSEIFKNMLDSDDCKEAPNEAITLPELNHEELESLLTFLYRGSLPNDVVEKHVYSL
SIAADKYDISFLQKFCERQMLTSLSSSNALDVLEISDVCSNLKLKDTSLSFIVKNMEDIV
FSPKFEAFALKNPHLSVQITRASWMDIKNRRNAL
>Sgl62819 E3_activity/RING/U-box 102 0.1
MNSPFEVFELRLPTLSGFLPTELLSASLITASDEISSITNIPRLQTKNILAMTRRVRLLS
PLFAEVQELHVPLLPSATLCFTELLSLMTRAKLLIQRCTEGSYLWNLVQTEVLSKEFHAI
IKDMSKALEILPLKLMDITIDVREQVELLRKQAKRADLLVDPKELERRKLVFQIIATTKD
SNNKIYGFLDVGRVKEIMISIGLRVSVDFAEEVSKLKAEAAIQGGTGGPIVVSQIYSLIH
LLTHVRSMIFSFEENEMAFELLKQKNAASKLAPSTSQVIPTDIPNEFRCPITDEIMREPV
VVATGHSYDRDSISKWIVSGRKTCPKSGLKLPHMALIPNYNLKSLIHQWHHDNNIKLDEF
TASSSKQHNTNTTRILGINAVKLTSEFLVGKLATASPEMQCRAAYETRLLAKRSMDNRKT
IAEAGAIPFLVNLLNSNKPAMQENAITALLNLSINSDNKFLIVEAAALEKIIAVLENGET
MEAKENAAATIASLLIVDDYKASIGAQPRVIAGLVHLLREGDTKGKRDAAIALTNLALYN
PNQRRVVHEGAVPLLIDILMDDKAGITDDALALLALLSECSEAMEEITKTTINDLMILLI
DLLRFGSLKGKENSITLLLALTKDSTEVVKHLDPQSFSLLRNLIANGSSKTREKAGLLLR
ILIKCCSNPANL
>Sgl62821 E3_adaptor/Cullin_RING/DCX/DWD 30 1.1
MPRTTTIEAPGCPPLRALTFDNIGLIKVIEARSKQNGVPKVVDRWGDPDSSKAVLAASIN
SSDNPLLAVARKNGAIEVLSPSTGESCFSISDDGDGTSPIDDPIVGLHLFKKQTIKSSPR
SCTLLTCTTKGKASLRRVEYFVSDADSASCATPETWNVCGSGEIHCSKVHVDEGYSVFGG
KGVELNMWDLENTTKIWSAKSPAKNSLGIFVPTWFTSLTFLSKDDHRKVVAGTSNHQVRL
YDISAQRRPVLSIDFREMPIKAVAEDLDGNTVYVGNGAGDLASYDIRTGKLLGCFLGKCS
GSIRSISRHPEHSVIASCGLDSYVRFWDTNSRQLLSSVFLKQHLTNVVFDSNFSDEETVT
IPTDAVPVIEEQSLNEKPSLNEDEVVPVKRKKSSKVKGEGKKKKSKKAKKVKGEVHDDE
>Sgl62826 E3_activity/RING/RING 36.9 8.2
MTTMQHNRHLLNHHSQLTPQENSRLLHWHYSQFDDHNLQIHGQTLFYLFILFSIILLVTL
LLLYARWYFRFRHAHYPYSSSHQQTSHATHQSQPCDEKSRGLDPLAIQAMPIILHQSSAV
GREDEMECCICLGVFEDGDKVKVLPKCDHRFHSDCVDRWLSTQSSCPLCRLSFTVIKPSD
SLSLPV
>Sgl62840 E3_adaptor/Cullin_RING/DCX/DWD 22.8 11.7
MSKKSSDKNMILRQQYSIPIHSVFEAAEIPLHNNQSVVGVLPQPCSCGYRVLLAYDNGVI
VLWDITKDQMLCVRGWNYHQMNETDAGGSTSSRSNEEKDQMLGDDQRDKDIISLCWASSD
GSILAVGYVDGDIMLWNMSDTVSGKDYKAGNPANKPVKLQLSSAQKRFPVIVLHWSASGA
LDDHGGQLFVYGGDEIGSSEVLTILNLEWSPKKDALKSVVRTNVTLQGAFADIILLQSCS
VLEDTGSTSLLLLTSPGELHYYDSPCLSGYNISDQDKSSAIPFPYRSVVPTSEPYMTVGK
FVSVLENTKCKSALSKFASTMELQETYTSSDKISKWPLNGGVPCHLSLQGERKVERLYIA
GYQDGSVRVWDATYPILSPIFVLNPEVLSITNAGTEGSVSALDFSSETLNIAIGNSSGTV
HLHSLIKDCNENRPQVVPKMQSENEVCESNQGSGSNSSIVFTLSTSPIITLRYTNFGTRV
AVGYKSGQVAMLNISSSSVLFFIDTLSGPGSHVVSFSPAISLEFYGLSTSLDKSEPHGKS
ESRKELICSITNDLHIAVLDNSTGDVIGSVSKLHHKESIAISMYILVGAKCITEVSGGEG
GEDIQFLLQEEKEEAEALQVSQAEIDYLDGVNQSIDSVQSSMDLQILICCTEVLLLYSLK
SVMQGQVDSICEVPLLKTSCWTSVFKKNKEEYGLLIFYQTGFIEIRSLPNLEVWGELSLL
SILRWNFRINMDKSMSCTEKGQITLVNGCEFVILSLLASENDFRIPQSLPCLYDEALTAA
LDLNFSANQRTSKESSSGILGEIMRGLRTSKEAQSTNTVDSPKSLRSVFNKVFSSSKPAA
SAAAKDAGKVEELSIDGPLRVSPIAPKSEDENKDKSTERKKLFDGGTSETKPRQRTIEEI
KAKYKKAGDTPSATASAASAASEAKNKLLERQEKLERISENSEELRNNAENFSSMAKELA
KKMENRKWWQL
>Sgl62852 E3_adaptor/Cullin_RING/SCF/F-box 21.2 0.0
MNVPKLLSSCNELPEEVLIEILLRLPVKSLIRFTSVCKYWFSLIKSPPFAIKHFDTRINL
LPQNDSHFFLTFSSHGDPIAKFLSYETLEISSIFECKPFDDYWDSVYRVSWSFSGPCNGV
FCIEVRKLRSVLLLWNPATREVFVPNQPNQILNFVGFGFDCKTNDYKIVMFDYSGSVQLY
SLRSDSWRGIEAGFSLGEDKDIIEGNHEKVSI
>Sgl62916 E3_adaptor/Cullin_RING/SCF/F-box 12.5 0.0
MSNNRRTMSDEILECILPYIEDPRDRSSISSVCRRWYELDRLTRKHVTIALCYATTPQRL
HDRFPNIESLRLKGKPRAAMFNLIPDDWGGYVRPWIEILESFRRLNKLHFRRMIITDSDL
QFISTVKGHSLQSLKLDKCSGFSTDGLFYIARSCKRLRTLFLEDSNVDEKNGDWFHELAQ
HNTVLETLNFYMTFLEQIKVDDLELLARNCPLVSVKIGDTDLVHLGNFFRTATRLQEFSG
GSFNEDLDQYANVVFPTQLTSLGPMYLVESHLPVLYPVAHLLQRLDLVYASLNCEGHCDL
IRRCQNLEVLETTNVIGDQGLEVVSLMCKKLKRLRIERGADEQGLGVEPGVVTQMGLIAV
AKACPDIEYLAVYVTDITNEALECVGAHLKKLTDFRLVLLDIKETITDLPLDNGVRALLQ
GCQNMQRFALYLRQGGLTDMGLSYIGEFSRKVRWMLLGFAGETDEGLLELSKGCPSLEKL
EMRACCFTEHALATAATRLTSLRYMWVQGYRASQTGIVGILQMARPYWNIELIPGDQYDY
NGNDGQPVRVDHPSHIVAYYSLAGQRTDHPQSVYPLALPDL
>Sgl62926 ULD/UDP/UBQ/UBQ_PIM 76.6 0.2
MQIFVKTLRAKTITLEVKASDSINNVKAKIILKLGTPSDQQRLIFGGKQLEDGRTLADYN
ILKESTLHLVLRLRGGGYGKMNYPPTLLELARKYMQYKKVCRKCYARLPLRATNCRKKKC
GHTTELRTKKMFQPPKDGGGKEKNKK
>Sgl62943 E3_adaptor/Cullin_RING/SCF/F-box 22.4 0.0
MVEIGEESESRVSRSSSFREIDDSLKQVAALGVGGSRNPSPVGRCCSRNTSPVGRAGSRN
TSPCKQKVVKTKPRGLDEETMATFSKVVQPDVQMEDNIWAMLPEDLLNEILARVPPFMIF
RLRSVCKRWNSILQDSSFLKFHSQVPSHGPCLLTFWKNSQIPQCSVFSLPLKTWYRIPFM
YLPQWAFWLVGSSCGLVCFSGFDGLTFKTLVCNPLTQAWRTLPSMHHNQQRQLIMVVDRK
DRSFKVIATCDIYGDKSLPTEVYDSKVNSWSVHQIMPAVNLCSSKMAFCDSRLYLETLSP
LGLMMYRLDTGSWEHIPAKFPRSLLDGYLVAGTQKRLFLVGRIGLYSTLQSMRIWELDHS
KIQWVEISRMPPKYFRALLRLSAERFECFGQDNLICFTSWNQGKGLLYDVDKKVWSWIAG
CALQSYNSQVCFYEPRFDASIY
>Sgl62953 E3_adaptor/Cullin_RING/DCX/DWD 53.1 14.6
MMSWLGECATIIASENQNIMVKRQRTAFPPSFVHSFDGSHMMMTAVAFQKAGLNCADEQV
REKFVELYEQPILENLLESFQQSFPTLSFPPLPERGDFILHSEGSFRVSIFLQLSYTKTA
AVISLHFLGSSSATQGDISYLAWNNKVHQILASTSHNGLTVVWDLRKQKSVISFYPDSQR
RRCSVLQWHPDVATQLVVASDDDNSPSLKLWDMRNTMSPVKEFVGHTRGVISMAWCPSDS
SYLLTCAKDNRTICWDVVSGEIVCELPAGTNWNFDVHWYPKIPGIISASSFDGKIGLYNI
EACNRYGVAETDFNAAPLRAPKWYKRPVGVSFGFGGKLVSFHSKAAPAGGSGGASEVYVH
SVVTEDNLVSRSSEFESAIQNGEKSSLRALCERKSQESKSDDDKETWDFLKVMFEDDGTA
RSKLLEHLGFSVPEEVSEPVQDDVTQQVSALGLEDNAAEMAGSVDNKEAASFAFDNGEDF
FNNLPSPKAETPVSSASNNFVGEAIPSEEQKQTEPEGLEESPDPSFDNAVQHALVVGNYK
EAVALCISADKMADALVIAHAGGASLWESTRDQYLKTSRLPYLKAVSAIVNRDLMSLVNT
RPLKTWKETLALLCTFAPKEDWTLLCDALAAKLLAAGYTLAATLCYICAGNIDKTVEIWS
RCLSAEPEGKPYVDRLQDLMEKTIVFALATGQKQFSSFLCRLVEKYAEILASQGQLSTAM
EFLKFLGEDISPELVILRDRIAVSSQPEKEAEKAMTYENSQVLSGSVYGADHADNSQSYY
QGTATGLVQSGSGPSHYGGNYPQHVPYDRNYAAPTPYQSTPQAPQPQMFVPLQSQQVLQP
NFPPPPVSAQPAVTPFQPAPAPILKNAEQYQQYQQPQTLGSQLYPGSTTPSYQSGPSGPG
PVGSMPPQTGGIPGQRMPQVMAPAPAPRGFMPVNSPGGVPQRPGMVMTQPSSPTQSAPAQ
ASAAPPAPPPTVQTVDTSNVPAHQKPVIATLTRLFNETSEALGGARANVAKKREIEDNSK
KFGALFAKLNTGDISRNAADKLVQLCQALDNGDYGTAMQIQVQLTTSEWDECSFWLGNLK
RMIRTRQNVR
>Sgl62982 E3_activity/RING/RING 24.1 4.1
MSNRILCKFFKHGACLKGEHCEYSHDWNAPASNICTFYQRGACAYGSRCRYDHVKLPQPQ
SSGSSSSNGFSGTAISGVTTSGMAPVSSVQPELSPISRPFHPSSKAAWNQQSVVSDTEEE
CIPQPRSNRLADQAICSFAAAGNCPKGEKCPHIHGELCPTCAKHCLHPFRPNEREEHLKV
CAKMQRHLETLKRSQDIECSVCLERVLTKPAGERKFGLLSECDHPFCIGCIRSWRNSSPS
SGMDVNSTLRACPICRKLSYFVIPSVIWYFSKDDKDEIVDSYMAKLKSIDCKYFEFGNGS
CPFGTSCFYKHSYRDGTLEEVVLRHLGTADGETVIPKDIRLADFLRNMHIS
>Sgl62987 E3_activity/RING/RING 30.3 6.6
MNENRPMEMYYTNNGYPYQTSENYMGFFDGFSHHPLNYGYPPVPMPNHQETAYWSMNMNY
RSDYSNAGSTSYYGYEVNNPLPRTEINRRTWEYSPAMHIEEPTMVVQSEENVVTTSDGAD
AEDCPVDDQEADSPEAAWQDDIDPDSMSYEELLDLGEAVGTQSRGLPQELIKLLPTSRYK
AGGFFSRKKSRDRCVICLVTYKIGDQQMTLPCKHVYHSKCGRKWLSINKTCPVCNSEVFG
EELGN
>Sgl63009 E3_activity/RING/RING 18.2 10.3
MAFHVACPITCKRICFCALGFPKSNLGSGDLFNEFSKIDEFLKDPWIIRVKEGATIQVPV
PKIVVPPPPPPPSQQHLLVRDDVVVSEEELLLSAQTKRVALQKKAAVASLAAEDFARRFE
SGSLLEAPKDAGVEEKVSSNVKVMCRLCFSGEHEGSERAKKMLPCSSCGKKYHRDCLKNW
SQHRDLFHWSSWTCPSCRTCEVCRRTGEPNKFKFCKRCDGAFHCYCMQPPHKNVSSGPYL
CPKHTKCHSCGSNVPGNGLSVRWFLGYTCCDACGRLFTKGNYCPACLKVYRDSEATPMVC
CDICQRWVHCGCDGISDERYLQFQIDGNLPYTCPTCRGECCPVNRLEDAVHELWRRRDEA
DRDLIASLRAAAGLPTQEDIFSISPFSDDEDDDLSSRKVEHGRARFSLKSLEDFSPKKIK
ESGKKPSGKKYVKKKGNQMYLDGTMEVKPEDYYETQSFGSRLRDKKQASQPHPDMFFSPA
SGSFSPSDRAYPNNEQGAMKHKSMDEVVENNVDKRASVLQIKSKKSNDTGVSEDVGQFAS
KPKTIKGTKLVIHLGGRNKTITNSPRSDSSSYQREQELTTLSGGNEAVSQDKIGDYQAEK
LDGTSNSDDGYRVDGAHDIKVGKRDRHIIKLGKGKSEPSGPQPHRGNGSFGQSTHFMSSR
KSNEASAVTEGLQNNLSKGEKISLRKHPDNRHVLPGDSNKSNHTSTPGLDASLKDSRPLL
RLKFKTPYPGSWAPASEEERGSVKGQRSKRKRPSSVVESPQKQEQEDVTEVQDENLMNEI
MDANWILKKLGKDAIGKRVEVHQPSDNSWHKGVVSNVIEGTSLLSIDLDDGRAKTLELGK
QGVRFVPQKQKRLKS
>Sgl63023 E3_adaptor/Cullin_RING/DCX/DWD 210.5 25.5
MEVEGEKETMENGNSVLCQLNDPEGTQLGTAMYLPQNAGPKELQQIVNTLLNNEEKLPYA
FYISDHELLVELGTYLQKNKVSVEKAVQIIYQPQAIFRIRPVNRCSATISGHAEAVLSVA
FSPDGRQLASGSGDTTVRLWDIGTQTPMFTCTGHKNWVLCIAWSPDGKYLVSGSKAGELQ
CWDPQTGKPSSTPFMGHKKWITGISWEPAHLQSPSRRFVSSSKDGDARIWDVTLRKCVMC
LSGHTLAVTCVKWGGDGVIYTGSQDCTIKVWETKQGKLIRELKGHGHWVNSLALSTEYVL
RTGAFDHTGKQYSSPEEMKKVALARYNKMKGNAPERLVSGSDDFTMFLWEPAVSKHPKTR
MTGHQQLVNHVYFSPDGQWVASASFDKSVKLWNGVTGKFVAAFRGHVGPVYQISWSTDSR
LLLSGSKDSTLKIWDIRTQKLKQDLPGHADEVFAVDWSPDGEKVASGGRDRVMKLWMG
>Sgl63026 E3_adaptor/Cullin_RING/DCX/DWD 118.6 9.3
MGFSAEAVLSVAFSPDGRQLASGSGDTTVRLWDIGTQTPMFTCTRHKNWVLCIAWSPDGK
YLVSGSKAGELQCWDPQTGKPSSTPFMGHKKWITGISWEPAHLQSPSRRFVSSSKDGDAR
IWDVTLRKCVMCLSGHTLAVTCVKWGGDGVIYTGSQDCTIKVWETKQGKLIRELKVFCFY
IFTFVFGFYKLMAAYSSSTSSLASKSFSISVLTIQSLVFNLLLSQSMIDLQLFSIFLYLN
SFTALLNELFVVLRVLGFGSILWFQPHANNVPTSC
>Sgl63034 E3_adaptor/Cullin_RING/DCX/DWD 55.9 3.7
MKPKNSEKFQIELLDKDILCIIFSFLDLFDLVRSSVVCKSWNSIIGSSKLLHALYLKQWA
NASNSSVDMGRPLNAFLEDLALQHNRSVLVEGSVAVDQWKGHAAGVSRCRMKAGLILTGL
GDKVMRLWSSDNYKCLEEYSLSDLDPLVDFDFDESKIVGLIGTRLCIWRRNGDRCIFPFL
PGTFPKGSCMRYLDPEAFIGCADGGVRVFDMYSKRCSRIIRMHNSPVSCLALGEDQLIVS
ASVRGSITVFGQSPDQQVATLRVSNHRAVKTLCYNPSSHMVFAGSIDGYAACWDLRTMQS
VWSKWVGSEISAMQFLRNDTSTLVVGGKDGVLHILDHDTGEILTRCALDSSKAKITSRNS
LYGSIERKRVKRIVGDANIGGVIPNPGAIPYPGAIPNPGIILNHLGILPNHNPGFLPNHN
PGIIPNHNPGIIPNHNPGIIPNHNPGIIPNPGVILNHNPRRRQSPISSLAVGMGKVVTTD
NTEYIRVWRFNKAI
>Sgl63043 E3_adaptor/Cullin_RING/DCX/DWD 38.7 0.0
MACIKSVTRSASVAMSPDSEYFAAGTMAGAVDLSFSTSAHLEIFKLDFTSDDHEIPLVAQ
SPSSERFNRLSWAKNGSNSEEFAMGLIAGGLIDGNIGIWNPLPLIRSESTDNAVIEQLTH
HKGPVRGLEFNALSPNLLASGADEGEICIWDLASPTTPKRFPPLQVWFLLMLCQ
>Sgl63081 E3_activity/RING/RING 24.1 4.1
MSNRILCKFFKHGACLKGEHCEYSHDWNAPASNICTFYQRGACAYGSRCRYDHVKLPQPQ
SSSGSSSSNGFSGTAISGVTTSGMAPVSSVQPEFSPISRPFHPSSKAAWNQQSVVSDTEE
EFIPQPRSNRLADQAICSFAAAGNCPKGEKCPHIHGELCPTCAKHCLHPFRPNEREEHLK
VCAKMQRHLETLKRSQDIECSVCLERVLTKPAGERKFGLLSECDHPFCIGCIRSWRNSSP
SSGMDVNSTLRACPICRKLSYFVIPSVIWYFSKDDKDEIVDSYMAKLKSIDCKYFEFGNG
SCPFGTSCFYKHSYRDGTLEEVVLRHLGTADGETVIPKDIRYGAFHRQLSIE
>Sgl63153 ULD/UDP/UBQ/UBQ_PIM 84.6 0.3
MKIFVKTLKGTNFEIEANPDDSVVDVKKSIEKSQGADVYPASQQMLIHQGKVLKDATTLG
ENDVVENSFLVIMLSKNKPAAPVPAPGASSASPAPASQPQTTTTTAPAAVAPVPAAPQTQ
TQTATEPAPAASEEANVYGQAASNLVAGSNLETTIQQILDMGGGSWDRDTVVRALRAAFN
NPERAVEYLYSGIPEQAEVPPVARTTAAPTGGQAGNPLAQAPQAAVPTSGAATNPASGAA
TGPNASPLDLFPQGLPSVGSNANAGSLDFLRNSQQFQALRAMVQANPQILQPMLQELGKQ
NPQLMRLIQEHQSDFLRLINEPVEGGEGNLLSQLTSAVPPTVSVTPEEREAVERLEAMGF
RRATVLQVFFACNKNEELAANYLLDHMDEFENDDDEGLS
>Sgl63223 E3_adaptor/Cullin_RING/SCF/F-box 17.4 0.0
MSQIFDFFGNEEFYHGGSIYSNPKEAGSFLSLGIGNHVDVYFPNKRARISAPIVSGGESF
EEKKQVSLDVLPDECLYEIFRRLPVDQERSSCACVSKRWLMLLSSIPCEDLCNVNKVAAA
EAEEIESDGFLTRSLEGKKATDVRLAAVAVGSGGRGGLGKLMIKGTNSVRGVTDLGLKAV
ARCCPSLKTLSLWNISSVGDEGVVEIASGCHRLEKLDLCNCPSITNKSLLAIAKNCPSLT
SISIEGCQNIGNEGLQAIGQFCSNLKSVAIKDCPLVGDQGVASLMSSTSFVLTKLKLQGL
NVTDLSLAVIGHYGKAITDLVLSNLQNVNEKGFWVMGNAQGLQHLRSFTISSCQGVTDVA
VDAVGKGCPNLKQFVLKRCAFLSDNGLVSFAKAARSIESLQLEECHRITQIGFFGLLLNC
GPKLKALNMSSCFGFKDMILGFPLPSTQTPLRSVTVSNCPGLGDMTLAMLAKLCPQLQCV
NFNSLPCITDAGLISLIESCDAGAGLVKVGLTGCVNVNDNVVISLAKLHGGTLEMLNLDG
CGKVTDAGLVAVADDCLLLNELHLSKSAITDFGVASLARSKQLSLKILSLSGCSMLSDKC
LPFLVKLGRSLMGLNLQSCNSISSTVIDMLVERLFKCDILS
>Sgl63229 E3_adaptor/Cullin_RING/SCF/F-box 12.5 0.1
MSSIPASQTNPNPQIPQSSNSTKPKRKNKNSQKKKRNRNKNKNKKIPNWLELPEDIWSLI
FSKLYTIHIIENVQKVCSLFRKICKQPSIYKIVDMTLPDAYMDLPYDVNVMTRFIVDRSC
GCLVDIYLEYLCDDDTLMYIVERSRNLKHLRLGHYIHISDEGVVEAVKKLPELEEVELII
CSFSEAAIEGIGLAYPSLKSFSLNGVGSRHHGLVVDEEALSIAKSMPNLRNLQLIGNWMS
NEGLKAVLDGCPLLESLDLRACFHIDLSGDLGKRCEKIKHLRLPFDSTADYSHEAFTDNE
EYRRACYDSDDSGLSGMFGFCLDYDYEDYEDYEGYEDDIPLHYYGGNGFLDWGYASSD
>Sgl63230 E3_adaptor/Cullin_RING/SCF/F-box 13.4 0.1
MLLKSSSHSNSNTKFPQLSTCPKFKRKKNKSHTSKKKKTKKNNTPTLTPNWLELPEEVLS
LIFSKLNTVEIIENVQMVCMLFRKLCKQPCVFKTIDMTLPDAYMHLTFDANLMTRYAVDR
SSGCLVDIYLEDVCDDDTLMYIVKRSKNLKHLRLGHYIYVSDEGLIEALKMLPELEELEI
IICSFSADTIEAVGRTCPSLKSFALNNVGSKDHQFAGNEEALAIAKSMPNLRCLQLIGNS
MTNEGLKAILDGCPLLESLDLRACFLIDLSGDVGMKCEQIRHVRQPNDSTSDYSHQTCYD
SEKFPDYGSCDSGLDGGFFGY
>Sgl63239 E3_adaptor/Cullin_RING/SCF/F-box 12 0.0
MNLRSKKHRIGNEQGNDRDRLSELPDEILVHILSFLPIGDAVRTVLLRRFGKLWTLLRTL
TYDQNTCSGRFICKVMRYHTSPTIDKLEIRKKFGSEKEEIMEFLDYGLRKKTKDLALCYN
DYFSVPRTVFRNQSIVSLHLTKPSLDFTRKSQLHMGSLKKLELVYLCETDQRLQAWLSGC
PCLQELVIKYPFRLKALHFPAPSIEKLELDFCLRMKTPVHNLRRERYTLDCPNLKILHIN
EMCLETLEVIDVSSVREAKITECCKTRGNFDYFDILLDKFRNAKLFQLGNKAYMQLQQCD
SQKLGFQENRWTRLALRSVIEGSCLLGICRLLRNSRHLKELVIYADVDFSCNCNMLLHEL
SSPCLMQKLKNITIREYKKPCEGLLQLMKFLLRSAVALEKLVVVFIMKDQVNFLEGDDFI
WQFSSFPRASRKVSVAFVKEIR
>Sgl63288 ULD/UDP/UBQ/UBQ_PIM 84.6 0.3
MKIFVKTLKGTNFEIEANPDDSVVDVKKSIEKSQGADVYPASQQMLIHQGKVLKDATTLG
ENDVVENSFLVIMLSKNKPAAPAPAPGASSASPAPASQPQTTTTPAPAAVAPVPAAPQTQ
TQTATEPAPAASEEANVYGQAASNLVAGSNLETTIQQILDMGGGSWDRDTVVRALRAAFN
NPERAVEYLYSGIPEQAEVPPVARTTAAPTGGQAGNPLAQAPQAAVPTSGAATNPASGAA
TGPNASPLDLFPQGLPNVGSNANAGSLDFLRNSQQFQALRAMVQANPQILQPMLQELGKQ
NPQLMRLIQEHQSDFLRLINEPVEGGEGNLLSQLTSAVPPTVSVTPEEREAVERLEAMGF
RRATVLQVFFACNKNEELAANYLLDHMDEFENDDDEGLS
>Sgl63358 E3_adaptor/Cullin_RING/SCF/F-box 17.4 0.0
MSQIFDFFGNEEFYHGGSIYSNPKEAGSFLSLGIGNHVDVYFPNKRARISAPIVSGGESF
EEKKQVSLDVLPDECLYEIFRRLPVDQERSSCACVSKRWLMLLSSIPCEDLCNVNKVAAA
EAEEIESDGFLTRSLEGKKATDVRLAAVAVGSGGRGGLGKLMIKGTNSVRGVTDLGLKAV
ARCCPSLKTLSLWNISSVGDEGVVEIASGCHRLEKLDLCNCPSITNKSLLAIAKNCPSLT
SISIEGCQNIGNEGLQAIGQFCSNLKSVAIKDCPLVGDQGVASLMSSASFVLTKLKLQGL
NVTDLSLAVIGHYGKAITDLVLSNLQNVNEKGFWVMGNAQGLQHLRSFTISSCQGVTDVA
VDAVGKGCPNLKQFVLKRCAFLSDNGLVSFAKAARSIESLQLEECHRITQIGFFGLLLNC
GPKLKALNMSSCFGFKDMILGFPLPSTQTPLRSVTVSNCPGLGDMTLAMLAKLCPQLQCV
NFNSLPCITDAGLISLIESCDAGAGLVKVGLTGCVNVNDNVVISLAKLHGGTLEMLNLDG
CGKVTDAGLVAVADDCLLLDELHLSKSAITDFGVASLARSKQLSLKILSLSGCSMLSDKC
LPFLVKLGQSLMGLNLQSCNSISSTVIDMLVERLFKCDILS
>Sgl63364 E3_adaptor/Cullin_RING/SCF/F-box 15 0.2
MSSIPASQANPNPQIPQSSNSTKPKRKNKNSQKKKRNRNKNKNKKIPNWLELPEDIWSLI
FSKLYTIHIIENVQKVCSLFRKICKQPSIYKIVDMTLPDAYMDLPYDVNVMTRFIVDRSC
GCLVDIIWSIFVMMIP
>Sgl63366 E3_adaptor/Cullin_RING/SCF/F-box 13.3 0.1
MDNSLHHRSSPFTMLLKSSSHSNSNTKFHQLSTCPKFKRKKNKSHTSKKKKTKKNNTPTL
TPNWLELPEEVLSLIFSKLNTVEIIENVQMVCMLFRKLCKQPCVFKTIDMTLPDAYMHLT
FDANLMTRYAVDRSSGCLVDIYLEDVCDDDTLMYIVKRSKNLKHLRLGHYIYVSDEGLIE
ALKMLPELEEVEIIICSFSADTIEAVGRTCPSLKSFALNNVGSKDHQFAGNEEALAIAKS
MPNLRCLQLIGNSMTNEGLKAILDGCPLLESLDLRACFLIDLSGDVGMKCGQIRHVRQPN
DSTSDYSHQTCYDSEKFPDYGSCDSGLDGGFFGY
>Sgl63377 E3_adaptor/Cullin_RING/SCF/F-box 11.7 0.0
MNLRSKKHRIGNEQGNDRDRLSELPDEILVHILSFLPIGDAVRTVLLRRFDKLWTLLRTL
TYDQNTCSGSFICKVMRYHKSPTIDKLEIRKKFGSEKEEIMEFLDYGLRKKTKDLALCYN
DYFSVPRTVFRNQSIVSLHLTKPSLDFTRKSQLHMGSLKKLELVYLCETDQRLQAWLSGC
PCLQELVIKYPFRLKALHFPAPSIEKLELDFCLRMKTPVHNLRRERYTLDCPNLKILHIN
EMCLETLEVIDVSSVREAKITECCKTRGNFDYFDILLDKFRNAKLFQLGNKAYMQLQQCD
SQKLDFQENRWTRLALRSVIEGSCLLGICRLLRNSRHLKELVIYADVDFSCNCNMLLHEL
SSPCLMQKLKNITICEYKKPCQGLLQLMKFLLRSAVALEKLVVVFIMKDQVNILEEDDFI
WQFSSFPRASRKVSVAFVKEIR
>Sgl63407 E3_adaptor/Cullin_RING/BCR/BTB 21.2 0.0
MSSQSSNSRRRSLTMERTGSLAMERTGQWVFSQDIPTDIIVQVDNSTFSLHKFMLVAKSN
YIRKLILESKESDLDRIDLSNIPGGVEAFEKAAKFCYGVNFEITVHNVAALRCAAEYLQM
TAKFCENNLANRTEDFLCQVALNTLSGAIIVLKTCEDLLPMAIDLNIVQRSVDVISAKAC
SEAMFPSRTPPNWWTDELSILGISSFEKVITSMRSRGAKTLTIASALITYSERSLKDLVR
DHSGNGIRSLSSTENSEWIIQQREVLECIVALMPSEKAAFPIKFLCSLLRGAIFLKASTS
CKNELEKRVSAIFEHVTVDDLLVLSFTYDGESLFDLESVRKVISGFVSKEKSVDVFNGGS
FREVCSGSMQRVARTVDTYLGEIAACAALSISKFNGIANLVPKDARRNDDELYRAIDIYL
KSHPNLDEIEREKVCSAMDPLKLSYEARVHASQNKRLPVQIVLHALYYDQLKLRSGENDH
GSLPEAVATRGQLHSDVSLVKENEALKSELMKMKMYISDLQKNNNNATTSRSSTSNNGMP
KKTFFSTMSKTLGKLNPFKHGSKDTSHLDDEVDLTKPRKRRFSIS
>Sgl63419 E3_adaptor/Cullin_RING/SCF/F-box 31.6 0.3
MVVDDVEEDRLSSLPDGILINILSRLEIHNAAATSVLSRRWRRLRIVKPNYQKTVLQATK
MGEDKHNNGVPKVEQLKDRLSSLSDEVLIQNILSRLSIHVAATTSVLSRRWRDLWKGVTC
FDFTSIAPGTRNCLNISSGMYDIIRQLNSPKLSVFRVHMQAYSLSCSPKIVESCFRELCC
RKVDQIVIKLEFQPFDFFCVPACLFQTKSLVDLITLLSSCTIRLPKCATIIELPKLKRLH
FHGLAAIPLWFIGTIFSSCPLLESFYVRFVDDIDSQHDIRIVAPNLKSLELHKFVVVQTQ
TQTQTPGAKIFIDAPRLTNLGISDSTSCYHFVHNPTLLDNASLKMTAYDKVKMRSIVVED
YLRRMSLFFKGMSCVCKLRLSIEDDHEPYSFHTYLNHPLKNHGRHRRQQTFPNLASLRLR
WNGRSLYGWENSLLLLHSFPNLRFLSMFLNEYKNSYNYWRHASDSVPDCLAYKLKTIEIT
MITINWNSIDAELDLLAYILSNAMVLEKLFVSVEFENIWKETRLWNARSFCKSLFNLPRG
SSICEIEFETTNLKASSTGTGLKMTENSHSKRIGNAVNVQERLSSLPDDILIDILSRLEI
HNAAATSVLSRRWRDLWTAVTRFKFLDPDYGLLENKQTDCPNSRDSRTNFLDILRQLKSP
KLYAFDIHRVELKPLGLIKASVNLRASMRDEVDVNEDDYNYEYPMSKFVAELSSVHELQL
NIFVAWERLVYNKSDLVSLRKSLDGMNNLIGWKDLLLSLQRFPNLNNNNLKTNNMTFFWS
SRQSRNRGCRGVDEIRSKPSKSGDIELIMLKAARMAENNYSNRITEDVYVEDRLSSLPDD
ILIDIISLLEIHNAAATSVLSRRWRHLWTAVTRLKFLDPDIKKVCPYRDWINFLDIFRQL
TSPKLYALSIHHVKPVSVSCAPNVVEECVRQLRCRKVEQIKIHINNCHARRIPVFHTSAA
SLFQIQTLVTLDLKCKIQLPENAPEIQLPNLKKLHMAAPSNHFRRTKIFIDAPILTSLTI
NDCSSCYYFVQKPLGLIKASINLTFAGPEVHVRDDYYEHYMSKFLAALSNVRELQLKLFI
GWEQRRYVENYNYSPKTTVYSDLVSLRTAIDGMGLEGWKGLLRSLQRFPKLNHLKLDIKT
ANHGSLICIS
>Sgl63426 DUB/USP 230.2 2.7
MSRPATRNKNKRNRPEDEVEVKSEVLRRIHTTGQVTNDDLAQLYNIRKAVCQGCRVNTKD
NPNCFCGLIPPPNGSRKTGLWQKMSDVISSFGPDPTMDLRSSDDSPAGLTNLGATCYANS
ILQFLYMNRAFREGIFSVEPHVLKQQPVLDQLARLFAQLHGSKMAFIDSAPFIKALELDN
GVQQDSHEFLTLLLSLLERCLSYSGVPEAKTIVQDLFRGIMSHVTRCSKCGQTSEASSNM
EDFYELELNVKGLKSLDESLSDYLCEEKLEGDNQYHCDSCGTRVDATRSIKLRLLPPVLN
FQLKRCVFLQKTTTKKKITSAFSFPEELDMGFRLAESSESALVYGLSAVLVHKGTAVNSG
HYVAHIKDESSGQWWEFDDEHVSNLGCHPFGEGSSCPVPKIDDTSSLEVKNSVSDQVHND
VDQRGSSNVNSHAASYSSSDAYMLMYTLRPRKVNQNGSMVSNASNANIAGTSVLANCLSL
PPHLAAEIKELNDLYLDSCEKYKSRKEQEMKSITERRQEVRSVLSEAPVPSIEEPYYWIS
MDWLRQWADNVTPSAIDNSNIECMHGKVPVSSVVAMKRLSANAWTLLCSKYNGGPCLGKE
DYCMDCLINSAHSIVSADSYKDRRACMKEVAEAALAGNSLDGKLYYISKTWLNLWLRRKA
SDNPSEADTGPTASIRCPHGQLLPEQATGAKRVLVPERLWIFLYENSNLVKPDDQLGCST
FPSDAETCTECCIELTEVASWEDTLKAVKLKQRQNHEKLALGKGVPLSSNCKYYLLPSSW
LSTWRTYINASGKNISSTIEPAPLDHVINSLICPTHSRLLERPLGLTYKRGVIMQKISAT
DGLMMISENDWKHFCEEWDGKEERGILAEVEFKSLTEGSCQEMPIAVEHMNGDQNNEMDS
REPVIKTSPEVCEECIGERESCELMKKLNYSNEDICVCFVRGKEPPKSILEASGNNFEAD
RRTSKRSRKTSFGNSKNLTVSGSTTIYQLKMMIWESFGVVKENQVVHKGSKVIEGECDTL
ADFNIFPGDMLWVTDSEIHEYRDIADELSEQKFDMREAEEGFRGTLLTSNSTSQLV
>Sgl63447 E3_adaptor/Cullin_RING/DCX/DWD 13.5 1.8
MEPPQPPSSPPSAMEEEQQPPPPQPPPEEEEEVEEEDDEDDDEDEDEEEEDEEEDVEYEG
LILKAQKFMELITSSPDNPNPKALHGLASLLESQESRYMEEADHSSSNDTRASHNIGRLG
SLIRENDDFFELISSKFLSESRYSISIQAAAARVLLSCSLTWMYPHVFEDDVMENIKDWV
LEDSSQNSGDDGLWKRQFGDSKCSDFDMRKTYSIGLLALCLTSGSQVIEDVLTSGLSAKL
MRYLRNRFLGETSGSQKVASRVAESRSVPLGGVGKGRDESHPRSRPTLESASLDDSRVED
GGSADLGCQRDFDRSFNRQLHGEERRISREPPDGLAEEVDIYDADIDGEVCRRGGDVHDG
RLKTSDRNGPGRYLHDEDYDGSERDDSSRYRLSRGLVRFRGKTRASETNTDPEQHIMSPG
SGSRGGQIRSGRERSSMRNLDGKRVTDSKKNLNRTSAESTGIEREETDECIQECRVGSKD
ISDLVKAAVRAAVAEARAANAPTEAVNAAGEAAAELVKSTAMDEFKSTNDEEAAFLAASR
AASTVIDAANATEVSRNPNSVNADLPNDGAAEAETNEDIEFFIPDSDALAQQREKYSIQC
LMLLGEYVEVLGPVLNEKGVDVCLALLQRYSDEKQKTEIVSFLPDVLKLICALAAHRKFA
AVFVDRGGIQKLLAVPRVLHTFFGLSSCLFTIGSLQGIMERVCALPSDVISKLVELGLQL
LECPQDQARKNAALFFAAAFVFRAVLDAFDSQDGLQKSLGLLHDAASVRSGANSGTLGAS
APGVLRNDRSNADILTSSEKQIAYHTCVALRQYFRAQLLLLVDTIRPNKSNRSTSRNIPS
SRAGYKPLDISNEAIDAVFLQIQKDRKLGPALVRARWPAVERFLACNGHVTMLDLCQAPP
VERYLHDLLQYALGILHIVTLVPNSRKLIVNATLSNDRVGIAVILDAANGPGYIDPDIIQ
QALNVLINLVCPPPSISNKSPLLAQNPQSASVHTSNASTEARDRNAEARERNGEPSTTDR
GSSMNITMQSPSSNLASGLVGDRRISLGAGAGCAGLAAQLEQGYRQAREAVRFNNGIKVL
LQLLQTRVVLSPAILDCLRALACRTLLGLARDDTIAHILTKLQVGKKLSEVIRDLGNQNP
GTEQNRWQTELTQAALELIAIVTNSGRASTLAATDAATPTLRRIERAAIAAATPITYHSR
ELLLLIHEHLQACGLSSSATTLMKEAQLTPLPSLSASPSLAQHACVQEMPSIQIQWPSGR
APDGFLNNRSKITQNEELHSKGDSAFSLKKKPVLFSPSFSARTKGRPSTEQQTSSISKAL
GSSKRTLGSAAPLEPSSAPTSEKTDDAEIHTKTPIVLPMKRKLTELKEVAPGSSAKRLNS
NDHGLKSPVFQTPNSTRRGNLLSDLYGSFTPSSSARDLHGRQAPLAGQADGFDDSQYNDT
SLSSNQPRLLSDSQPVNSERLTLDSIVVQYLKHQHRQCPAPITTLPPLSLLHAHVCPEPR
RSLDAPSNVTARLSTREFRSMYGGIHGTRKDRQFVYSRFRPWRSCRDDAAALLTCMTFLG
DSSQIAAGSHSGELKIFDTNSSNILENCTSHQNPLILVQSSPCNKTQLVLSSSTIDVKLW
DASSISGGPIQTFEGCKAARFGNTGTCFGALPTDTSQREILLYDVATKQLDRRFSDTSSG
PSGKSVYSILHFNPSDTMLLWNGVLWDRRVSGLVHRFDQFSDYGGGGFHPGGNEVIINSE
VWDLRNFKLLRSVPSLDQTNITFNSSGDVIYAILRRNLEEMSSANFTRRSKHPLYSAFRT
LDAVNYSDIATIPVDRCVLDFTTEPTDSFVGLVTMDDQEDMYSSARVYEIGRRRPPDDDS
DPDDVESDDDDDDDDDDDVDLDPLLGTDFDIDGGSDGDMSNDDSATDDDDDDDDDGDFLV
DGAGFDVGGGEILDMVTEGDEDYDSDMMGSFSSGDGFV
>Sgl63470 E3_adaptor/Cullin_RING/SCF/F-box 22.3 0.0
MMMSKKTKNMMDSLPEELIIDILSRVPAKTVGRCRCVSKPWNSLLSQPEFLKTHLNKTQQ
SNLVQESLILENADGRSLYSAQLNNVFDEITIKATNLDFIDNLFDSTIFVAPICNGLMLV
GDFQNKFYLINPLTKETKQLPEITYPVRPHGQCVSSFGVGYDSMTDDYKVVFIFSVHIRH
YDEDMMHEYDCLYIDKIANVYSLRNNSWTVAEIPPNYCGCCLSKSGVYVNGFMHWVTRSV
SKKYAVILTFDLRNEKFGEMQRPFSEYSNNFHFGYYNIHRVGGFLCVRYILGGGVIESWR
MEAYGVFESWTKCLIVYPHQCKMLPLCLMPKQQLLLAKDLCNFRFMGQKLVVCDLKDGSL
KDIQVHGTPDGYSAEWTFIESLVSPHHG
>Sgl63477 E1 220.1 0.0
MDGEQLTEQETALYDRQIRVWGADAQRRLSKAHVLVGGMMGTIAEFCKNIVLAGVGSVTL
VDDRRVTEESLTANFLIPPDEKLYEGRSIAEVCCDSLKDFNPMVHVSVEKGDLSKLGTDF
FEKFDVVVISCCSLSAKKAINEKCRKLSKHIAFYSVDCRDSCGEIFADLEKHSCTKKQAD
ETVECVLHYPSFAEAIAVPWKSLPKRVSKLYFAMRVIERFQDSEARVPGETSAADLPSVL
KLRKELCEAQLFSESQIPDCLLQRLLCGKLEFPPVSAIIGGILGQEVIKAISCKGEPIKN
FFYFDAVDGKGIIEDISNPNPVT
>Sgl63511 E3_adaptor/Cullin_RING/SCF/F-box 17 0.0
MSSSSSNRWKSTQNDTNDDDTVDWLELPSDLLIQIAENLRSVEDYVAFSCVCRCWRNAIS
GCDMNKLRYNWGHHQMPWLLLTDGNQKILDTSSHNWVQRFQNPWVLVIGDDIEEILETKD
EVLLLLLNDEEELMMDNNGKSYKRSMLNLNNGNTYTVNCPQGYRRNCWGSSHGWIFAQDN
TPNLCVFNPVTNTRLDLPPKTTLPLRLELVNSYAITTAAIFNRVLPSDNDDVPGGRAEAE
GDPTSLFVVLIYNFYTTIVFAKPGDTEWTEIGYTSPGEHLLDVSYGNGRLIVLGEMGAIG
YCDLERSHQQQQQDLDEPLGLTWYDCNLELLRNQQSLGIDKPFLLSDYTTYLAHCGEDLL
LVVRMLLIDKNTRNVNYANENYWTFKFRVYKFLIGDEQWEELEDLGDVALFVGSNTTMSV
CASDVGCQPNSIYFTDDSKHCYTLTQDRLGGADMGIFRMADQSILPLDLKNNNTHTRSYY
CCPLWFIPTL
>Sgl63512 E3_adaptor/Cullin_RING/SCF/F-box 13.5 0.0
MAPRSVLKHRDKNRSNNDNNNNNNVDWLKLPSELLVQIAEDHLPSVNDYVALSCVCRCWR
NAIKSGCDMNKLRYNWAHHQMPWLLLTDGNQKILDTYCYNSEPILTNPEDELLLHDEKEL
RVDNGKSYKRSMLSLIDGNTYTVNCPQGFRRKCWGSSHGWIFTQDNTPNLYVFNPLTSTR
LNLPSILSLVPNFFEKKVIKRAAIFKVPSDDDVPRAAGDPSLLVVVIYGNFPSNVAFAEP
GDTEWTKIDDTNKVGVILDVSYSGDQARGRLVVLGTMGVLGYCDLDRHQGHPVRLTWYDC
KLGFLNQPFWVLDSFLADYNVYLVHRGEDLLLVVRILKLDEHRRGEDYVYDNYSTTEFKV
YKFVCDNKQWKELKDLGDAAVFVGSNTTMSVCASDVGCQPNSIYFTDDSKHCYTLTQDRL
GGRDMGIFRMADQSVLPLDLKNNTHIRSYYCCPLWFIPTL
>Sgl63524 E3_adaptor/Cullin_RING/SCF/F-box 15.1 0.0
MELKSTQNNTNDDNIVDWLELPSDLLIQIAENLRSVEDYVAFSCVCRCWRNAISGCDMNK
LRYNWGHHQMPWLLLTDGNQKILDTSSHNWVQRFQFPWVLVIGDDIEEILETKDEVLLLL
LNDEEELMMDNNGKSYKRSMLNLNNGNTYTVKCVNCPQGYRRNCWGSSHGWIFAQDNTPN
LCVFNPVTNTRLDLPSKTTLPLRLELVNSYAITTAAIFNRVLPRGRAEAEGDPTSLFVVL
IYNFYTTIVFAKPGDTEWTVIGYASPGEHLLDVSYGNGRLIVLGEMGAIGYCDLERSHQQ
QQQDLDEPLGLTWYDCNLELLRNQQSLGIDKPFLLSDYTTYLAHCGEDLLLVVRMFLIDK
NTRNVNYANENYWTFKFRVYKFLIGDEQWEELEDLGDVALFVGSNTTMSVCASDVGCQPN
SIYFTDDSKESYTLTEDRLGGADMGIFRMADQSILPLDLNNNNTHTRSYYCCPLWFIPTL
>Sgl63540 E3_adaptor/Cullin_RING/DCX/DWD 101.6 7.7
MGKDEEEMRGEIEERLINEEYKIWKKNTPFLYDLVITHALEWPSLTVEWLPDRDEPPGKD
YSVQKMILGTHTSENEPNYLMLAQVQLPLEDAENDARHYDDERSDFGGFGCANGKVQIIQ
QINHDGEVNRARYMPQNQFIIATKTVSAEVYIFDYSKHPSKPPLDGACNPDLRLRGHSTE
GYGLSWSKFKGGHLLSGSDDAQICLWDINATPKNKTLDAMQIFKVHEGVVEDVSWHLRHE
YLFGSVGDDQYLLIWDLRTPSATKPVQSVVAHQSEVNCLAFNPFNEWVVATGSTDKTVKL
FDLRKLNTALHTFDCHKEEVFQVGWSPKNETILASCCLGRRLMVWDLSRIDEEQTQEDAE
DGPPELLFIHGGHTSKISDFSWNPCEDWVVASVAEDNILQIWQMAENIYHDEDDLSTDDA
AATKGS
>Sgl63544 E3_activity/RING/RING 25.4 3.1
MSSSCFTKKWHCRSNCCLNKGPQKSSGGGGDVKPKIKSSEIVEVQLNSNWDDVTCPVCLD
YPHNGVLLQCSSYEKGCRSFVCDTNHLHSNCLERYKSAHGIHAGSNSLSTSYAVASENSE
PVKPENNGKPTCPLCRGDVNGWVVIDKAREYLDQKKRCCEEERCSFVGTFLELQKHAQEQ
HPDSRPSKIDPARQLDWENFQQSSEMVDVLSTIHSEVPHGVVLGDYVIEYGDDDTADEFE
DYSQNEGNWWTSCILYQVFDNLRSNRNRRRSRTSDRRRGSRRSSNDTSNSDDGSVTSVEF
PDYRVDETDDDFVNSRGPGRSTFNHRSSRRRRSRFYDH
>Sgl63547 E3_adaptor/Cullin_RING/SCF/F-box 15.6 0.0
MIHQQEILEDILSWLPAKSIGRFRCVSKAWKTLLSQPHFIKTHLNRIKQSPFGVQSLILA
NYQSNSLFTTHLNDAHHMFDEMTVVATPLCFDDDHKFNIELIVYAQVASCDGLTLFEDEE
NRLLLVNPTTKEFKELPKSPFAFDPDVSSYTLFGVGYDSVSDDYKVVMIFFYNNDNDLNA
HRPDANEVFVNVYSVKNGTWKRAANSPYDHAVGHITSGVLVDGNIHWLASRTSDYSSVIV
GFDLGEEKFQELPPPSLVEGSKFVLNRLSTLGGNLSMYDLRYLDPQTNVWVMKEYGVKES
WTKFTIVDTQKKSVFRPLCLLGKEQVLVKDEETDEEKLVVYNLKDKSFKDVVVQGIADEF
GVGGTFMETLVSPHCSAEATREE
>Sgl63548 E3_adaptor/Cullin_RING/SCF/F-box 14.2 0.0
MIHQQELLEDILSRVPAKSIGRFRCVSKSWKTLLSQPYFIKTHLNRIKQSPFEVQSLILA
NYRTDSLLTTHLNSAHHMFDEITAVATALCFDNDDHKFNAESIIVAQVASCDGLALFVDK
EKRLLLVNPTTKEFKELPKLPFALDPDFWSFTMFGVGYDSVSDDYKVVMILFYANDIDVY
AHRTDDASDVFVNVYSVKNGSWKRAANSPYNHAAGLLPSGVFVDGHIHWIATRTLDNSSV
IVGFDLAEKRFREVPPPSLVEGSDFLFHSLLTLGGNLSMFVTTTLDPQTNVWVMKEYGVK
ESWTKLTIVHIQEDSTFRPLCLLGEEQVALVKDEYSGEEKLVVYSLKEESFKDVVFQGNV
DDFGVAGTFVKTLVSPHCSAEATREE
>Sgl63549 E3_adaptor/Cullin_RING/SCF/F-box 15.7 0.0
MIHQQEILENILFRLPSKSIGRFRCVSKPWRALLSQPSFIKTHLNRIKQLSSPDQQQPLI
AANYKGCSRSLYSIQFRNVDDETAAAFATNLISEYDQPFESKTCVIVQGSCDGLTLVQDY
KKLVLINFTTKERKELPKRAPYAPDGNGRGSDDNVVYGFGYDSVSDDYKVVALSYYNAFI
HIEPKKCTQMCVDIYSVKNGTWKRADNSPYDYCVAQSSPGVVVDGYMHWFACRISDYSYA
IVAFDLGDETFREVPLPDSCTSDDMDVYNLTTLGGCLCMFDMWISYKTEFWVMKEYGVGK
SWEKFRIVDAENYYSDREPLCLFGTEQVLVQKRQSLLKKLVMYNLKDGRVKGVVVRGIPN
VVDVRGTFMESLVSPHSNVEAAREEE
>Sgl63550 E3_adaptor/Cullin_RING/SCF/F-box 21 0.0
MNSSKVTNSPEHMLPQDILIDILSRLPAKSIGRFRCVSKPWKSLLSQPQFIKTHLNRTKQ
LLGEDEASLLFVSDDSGSLYSSHLKYAHHLFDEITISATKLCFDDHHFSSTQLCEMGSCD
GLVLVMDREDNVFLINPTTKEIKELPASPYAPNPRLSGTQYGLGYDSVNDDYKVVSISYN
CNCHGNDHGFCEMFVNAYSVRNGTWESGTRAKLEGSPYDHGVNYRYSSGIFIHGYIHWLG
VRLSDTSFVITAFDLEQGKFKEVSPPSGVLVLGDQNLGFNHLVELGGCLSWYPSSSWFPS
SNAVDVYMMKEYDDIDSWTKFPIIHPEPIRVRPLCLLGKKQLVLLKNEGFFSQNLEMYNL
ERGTSKDIAVLGIPHAFSVGGGFIDSLVSPHCSIEAVREC
>Sgl63551 E3_adaptor/Cullin_RING/SCF/F-box 12.1 0.0
MIHQQQNILENILFRLPAKSIGRFRCVSKPWRTHLSHPNFIKTHLNRIKQLHNIEEQSLI
FVPKSKNSYSFHTSKLENGMTPAFATHLIGFDDHPQFQCQSKLEYLGSCDGLTLIKGGAT
RLFLGNPTTKEFKELLGWPLHPRGHGFVTMYGVGYDSTTDDYKVVALFWYRPIHVDDQIE
GELFVEVYSVKNGTWKTANSCPFKFLIILNRSWVFVDGFIHCIAYRIQDESSFILAFDLT
QEKFCVLPYPSAMDMCVVTGHHLSNLGGYLCMYMTQDSETYIWVMKEYGVVESWIKFTII
DTEEKSEYRPICLQGTDQIVLAKKGDKKVNDKLVMYNLNEGSFKDIAVEGITDIFSVGGT
VMDTLVSPHCTVEAARED
>Sgl63552 E3_adaptor/Cullin_RING/SCF/F-box 17 0.1
METPNKLTKMIHQEEMIHHEEILEDIFSRLPTKSIGQIRCVSKPWKTILEQPHFIKTHLN
RTKQPPIEVQSLILIGHYPNSIFIIQLEKPHQMVDEITISATSISLDDHRFDNESIIGSL
ASCDGLTVIEDDDRLLVLVNPTTKEFLELPESPFALDPHTSFSMYGVGYDSVSDDHKVVS
ISYYDSNYEFESEPDCSEMFVSVYSVKTGTWKRVRNSPYDHAIGKLTAGVLVNERIHWIT
CRKSDCSSVIIAFDLGTDEFREVPPPIWAEGKRIVYYELLTLGGWLCMYSANKVFKSDIW
VMKEYGVQESWTKITIVDPLMSEFRPICMLGTEHMVLMKDEETINEKVVIYDMNQAKFMN
VVVEGIPTAFCVGGTFMESLISPHSSVEALIEE
>Sgl63553 E3_adaptor/Cullin_RING/SCF/F-box 16.9 0.1
METPNKLRKMIHQEEMIHHEEILEDIFSRLPTKSIGQIRCVSKPWKTILEQPHFIKTHLN
RTKQPPIEVQSLILIGHYPNSIFIIQLEKPHQMVDEITISATSISLDDHRFDNESIIGSL
ASCDGLTVIEDDDRLLVLVNPTTKEFLELPESPFALDPHISFSMYGVGYDSVSDDHKVVS
ISYYDSDYEFESEPDCSEMFVSVYSVKTGTWKRVRNSPYDHAIGKLTAGVLVNERIHWIT
CRKSDCSSVIIAFDLGTDEFREVPPPIWAEGKRIVYYELLTLGGWLCMYSANKVFKSDIW
VMKEYGVQESWTKITIVDPLMSEFRPICMLGTEHMVLLKDEETINEKVVIYDMNQAKFMN
VVVEGIPTAFCVGGTFMESLISPHSSVEAPIEE
>Sgl63556 E3_adaptor/Cullin_RING/SCF/F-box 18.3 0.0
MIHQQEILEDILSRVPAKSIGRFRCVSKSWKTLLSQPHFIKTHLNRIKQSPFEVRSLILA
NYQSKTLFTTNLNNAHHMFDEMTAVATTLSFGDNDHKFNAELIVYAQVASCDGLALFEDE
EKSFSSIQLHSSVSSFDLHFTNSQIGNRFFQLSDPAATAADQANKEEVDSRSVFVGNVSF
FCPRKYRFRRLQSDIIC
>Sgl63557 E3_adaptor/Cullin_RING/SCF/F-box 18.5 0.0
MVYIPEELIIDILSRVPARTVGRCRCVSKQWKSLLSQPEFLKSHLNKTQNSNLVQESLIL
ANIDLRSLHSGQVNVFDEIITINATKLDFINPLFNTRIYVAPPCNGLILVVEEDKNKFYS
YLINPLTKETKQLPKLTYPDGKHGFLPQYVSLYGVGYDSVSDDYKVVVIFSFPFGYYEDA
YDESYDRMYLENIANVYSLRKDRWTVVENPSVYCGRFLSPGVCLGGFIHWSAIKVETDSE
YYSESDVILTFDLRSEKFGEILSPGSKDYHGYYPAEVQRLGKYLCVYYGLEDRDQILELW
RMEEYGMVESWTKYLIFDPDRFSLVPVCLMPKQQLVMGKDLFRFYGKDHKLVVYDSKDGA
FKDIQVHGTPAVGYSANWTFIESLVSFNELASL
>Sgl63561 DUB/JAMM 31.8 1.3
MDPNTLTSSAEIAKQTWELENNIVTMDPTSTSTQTQSSSSSSNPQNTDASDAIFYYDEAA
QSKFQQEKPWVNDPHFFKRVKISALALLKMVVHSRSGGTIEVMGLMQGKTVGDAIIVMDA
FALPVEGTETRVNAQADAYEYMVEYSQTNKQAGRLENVVGWYHSHPGYGCWLSGIDVSTQ
MLNQQYQEPFLAVVIDPTRTVSAGKVEIGAFRTYPDGYKPPDEPVSEYQTIPLNKIEDFG
VHCKQYYSLDITYFKSSLDCHLLDLLWNKYWVNTLSSSPLLGNGDYVAGQISDLAEKLEQ
AENQMAHTRFGSILAPSQRKKEEEPALAKITRDSTKITVEQVHGLMSQVIKDILFNSVRP
DQSQAESSEPEPMVEA
>Sgl63570 E3_activity/RING/RING 24.9 5.2
MEENSRKRSSGGLRRGTSLVLRDSAEKNRDRNVQVCSRVGCSSKLHSMNDTQIGSPSKAK
TPKKPFGSSALGKETIGSSSKTLASPNTSRKSFSETKKKLPSHLDTDSETSSLHDESEKM
SGKTRMRVHPEPEDQDPVEARSSGAGSSSGGPSNRFVKRNTPRFGLGRQDSAASSSSSVA
LKQANQGVRNGGTSSNKYNLRQLKCNSISDVVPSSSSPSSESNLSRKKDTGGRKRIGEAE
SSLSVRGKKIYGSTKDDRKNDTSNRGISISDSRRNRSSSPGNNDAASIRTRRLSSRTRLS
NQESRDVLPLVESPLMNPSSPHSDLATDAIDFNLENHFSGQTPASPLSSFRRPGSGSEHV
RPNRPVGPYEAGISRSLMNRDSLRQYNLDGIAEMLLALERIEQEEEPTYEQLLVLETNLF
LGGLGFHDQHRDMRLDIDNMSYEELLALEERMGTVSTGVPEDVLGECLKTSTYQGIAECR
EDENDVKCSICQEEYATGEELGRLSCDHRYHNECIDQWLRLKNWCPICKTSVAPSPSASL
PP
>Sgl63572 E3_adaptor/Cullin_RING/SCF/F-box 13.8 0.0
MIHQQDILENILFRLPAKSIGRFRCVSKPWRTLLSHPNFIKTHLNRIKQLHNNEEQSLIF
VPNFTFAQNHLDSRNISKNSYSFHTSKLENGMTPAFATHLIGFDDHPQFQCQSKLEYLGS
CDGLTLIKGGATRLFLGNPTTIEFKELLGWPLHPRGHGFVTMYGVRYDSTTDDYKVVALF
WYRPIHVDDQIEGELFVEVYSVKNGTWKTANSCPFKFFIILNRSWVIVDGFIHCIPYRIQ
DESSFILAFDLTQEKFCVLPYPSVMDMCVVTGHHLSNLGGYLCMYMTQDSETYIWVMKEY
GVVESWIKFTIIDTEEKSEYRPICLQGTDQIVLAKKGDKKVNDKLVMYNLNEGSFKDIAV
EGITDIFSVGGTVMDTLVSPHCTVEAARED
>Sgl63604 E3_adaptor/Cullin_RING/SCF/F-box 17.6 0.0
MRIWCCLPCFVVDDRENAMDGAREDEIKSENENLDEENEANEEEKLSSEGLSLELGLPGS
SSSSNNDKSVEGLKGGSKRDLGGFVVEREKSDLESLELSIGGSSSHHLNNLNELDFSLCS
NVNEHGNASFTTPVIEFDFDLYIKRAKVESEFNKSHYSADSPTFTDNNVDVIRRNMISPN
SSVCTRNNIECITHPVDDSVNTVIRDENGDIIEGSTDSSDMEDMAIPLDLSDDLLHMVFS
FLGHANLCVAAMVCKQWRAASAHEDFWRSLDFENRNISVAQLEDVCHRYPRATEVNLCGN
PDMHMLVMRAVSLLRNLEALTLGKGQLGESFFHALSDCPLLRKLVVSDAALGNGVQEISI
NHDRLQHLQVTKCRVLRVSVRCPQLGTLSLKRSNMAHVVLNCPLLHNLDIGSCHKLPDAA
IRSSVTSCPLLENLDMSCCSCVSDETLREISQACANLRELNASYCPNISLEAVKMPLLTA
LKLESCEGITSASMTAIAFSNMLEVLGLDFCNLLTSVSLDLPHLSNLSLVHCRKFVDLNL
RCLMLSSLNVSNCPALHSISITSNALKKLALHKQESLNSLSLHCQYLEEVDLSDCEALTD
SVCDVFNDGGGCPMLKSLVLDNCESLTTVGLHNTSLVSLSLAGCRAVTILDLKCPYLEHV
RLDGCDHLERASFVPVGMRSLNLGICPKLSALHIEAPHMVGLELKGCGVLSEASINCPLL
TSLDASFCSQLTDDCLLRTNASCPLIDKLILMSCSSIGADGLSSLCWLKNLTYLDLSYTF
LTDLQPVFNSCLRLTVLKLQACKYLNDSSLVALYTLGALPALRELDLSYGTLSQSAIEEL
LAYCTHLTHVSLNGCKNMHDLYWGFTELSRYQPSGLSSSQLINEPVELPRRSIECLTCVG
CPNVKRVYIPSIAQCTHLSSLNLSLSHNLKEVDVACSNLCFLNLSNCNSLEILKLDCPKL
TSLFLQSCNIDEETVESAISKCTMLETLDVRFCPKISAAAANNFRAVYPSLKRVFFGSR
>Sgl63612 E3_activity/RING/U-box 26.7 0.8
MASTVRFKFRSAATFDSVEIDDNQSSISIRDLKSKIVLKKHLNLCQDFDLVFSDSISGIE
YTDENTRIPSGSSVIIKRVPAKSPPLLRASDTSTGCLGARDANCVGVFDQPTMDIGVNDF
DDFGVDLCPPPHISLSDTAEKLQFNNNGKKDKVVSRCSQELLASCQKIESAHHAQSKPKD
SSANEESTLVMPKPKIEEQPLPERFPAKHSAMENSSMPSELKCSLCRTFFKEAVMIPCCQ
HSFCGNCIRAALSDNAKCPMCSSTKCKPEDLLPNVSLRQAIVRFLESQPLLNGSENDLQR
YAPDGESGIQVMDVSSATTIPPRLQLRSNKVMQSKLHDRAHLADKCTPDTLEDFSEFEGE
NDPQTMVHRTKEAVSCSKKEEEPSAFTRGGERNFAAPGRPNKGPRTCYMCGSPDHLIRDC
PGAAHCSTSQWNGVAPLPGTVSGYPPSYWPGSSPHSRPYINMYGSPGMMFYNAATAPISP
FAYPSYAPSMYGGYPVSNYGNVGGLTLPVGNIAMQPRHVEHLELQGCTKQQRNKEFDSER
DWNHNREHNVNTQHDFVDRGPHHSGDGFARRAEGKHKSRDNPDGDDTNLICDRQGNAAGH
LGCGRDLRIPQSDKSSSETDLLKDRVRVREDKHKKVHRTYRRNDEIEKNYGRDSSQKHYH
PKKESGKRKRMEHDERKSDRHSYSRSRSSLERSYSGGDARKRRDDSTHKSRHSKYNGKEM
HHDRGR
>Sgl63615 E3_activity/RING/RING 26.9 14.2
MGDSTQSQMEATTSSSSSRQAEGVLRGFAAAAPPEIMRAAEKDDNYASFISDACRDAFRH
LFGARVAVAYHSETKLLGQMLYYILTTGAGQQTLGEEYCDIVQIAGSYGLPPTPARRALF
ILYQTAVPYMAERMSSRIASRGMFLAESHSDDFGDRNALTGSHLSSETSSSSTSQISDSF
FSSLKERYQRLRLYIIQRWPTMLPVVRDVLQLFLRTNLMLFYFEGLYYHISKRTSGIRYM
FIGKPLNQRPRYQILGVFLLIQLCVIAAEGIRRTNLSSLGNSVQASLGTYNHSTGGGLPV
LNEEGDIITADSDKGKGASKCTLCLGNREHPTATPCGHVFCWNCIMEWCNEKPECPLCRT
PLTHSSLVCLYYSDF
>Sgl63649 DUB/JAMM 32.8 2.8
MDRLTRMFAGAGGALGHPPPDSPTLDTSEQVYISSLALLKMLKHGRAGVPMEVMGLMLGE
FVDEYTVRVVDVFAMPQSGTGVSVEAVDHVFQTNMLDMLKQTGRPEMVVGWYHSHPGFGC
WLSGVDINTQQSFEALNQRAVAVVVDPIQSVKGKVVIDAFRLINPQSMMLGQEPRQTTSN
LGHLNKPSIQALIHGLNRHYYSIAINYRKNELEEMMLLNLHKKKWTDGLSLKRFDIHSKT
NEQTVQEMLGLAVKYNKAVQEEDELPPEKLAIANVGRQDAKKHLEEHVSNLMSANIVQTL
GTMLDTVVF
>Sgl63677 E3_activity/RING/RING 19.6 0.0
MVTLMIMSLVWCNKAVTFFFNKFRTLDVSHLVYMVLMIKVNADVDVATAMDYSYEDEDED
DKSEKIRSVVRFCLEEFDKRGKNNIDGKQEDGDGDAAALPCSRVLHTDCLVPWITKGKNT
CPIPNKTIVPKRANSNPPTSTPNYGLKVKTHISSSSSFSENPTFAAAPSLSLLVSMAPPA
KDGKKADPKAQALKAAKAVKSGSTTLKKKAQKIRTKVTFHRPKTLKKDRNPKYPRISATP
RNKLDHYQILKYPLTTESAMKKIEDNNTLVFIVDLRADKKKIKDAVKKMYEIQAKKVNTL
VRPDGTKKAYVRLTPDFDALDVANKIGII
>Sgl63713 E3_activity/RING/RING 37.5 6.3
MSFINRPRVVINGTRRTRTYRFFWCRQCDRTVRIASANCSTFVCPFCYNLLFQEFHLPRS
SSFPSHNSELPTSLSSSSSSPSPAQLIDTMSQIINMPPQPRPAPLPPQENTLSNQPEPSD
QAVQDQTNENRTRSGITEFKMTADTMCTEPPCPICKEDFVVNEQITKLGCNHLYHSDCIT
PWLQINSTCPVCRYELPTQQGCTHHDHNNRARSSSSNNNSNNFRAANNYGHDYEFYGDFN
LRFEEVTNLSIPSWAELFSILWPFRLGALLDWSFPS
>Sgl63716 E3_adaptor/Cullin_RING/SCF/F-box 16.3 0.0
MEHNCIFPHDLVEDILSRLPVRDLLRLRCVCKEWCAVIDDASFIKKHYQVQYSICKVGSN
MPYFIREDKINRTEEAYLLSIHQGDIITLNLTDDLERDSNGVFPYGIDQFYMECRGCVNG
IICLSFINKIKTPFIDNCFLALWNPATREFKTVAYPNAPGLTYGHGFPILGFGFDLSSND
FKIFGVFTDDRENDDELVFYHKLYSLNTNSWKTIPNPPPKALGRLPWAMNDGYFDGVYYM
TTDDRQYNCRPSYDEIVSFNFASEVFTVSDLPQEAISLVTRSKIHQVMITLYKEKLGLFV
SHEVEEFGLCSIDIWVVTQLNDCGVPLSWQHLFTIEGTLDKLDMQVISTLMNGDLLLTYL
IPTEDMPSFEDLIKTPTFYHSIYNQSRGDYKKFEIDLVAFFRYVESLFSISSMLV
>Sgl63765 E3_activity/RING/U-box 57.2 0.0
MGSGKHRWKISIYRTPLSSSTTTTSKTQNSKPPNEFLCPISGLLMGDPVIISTGQTFERA
CVIACKKLGFIPTLNDGCNPDFSLVIPNLALKSSIDNWATASQLSPPKPLEFDDGLKVVK
SLMAAKAKEVRVTAELERVNSNPGSNPLEHAESELSRRQTRFGSTDSLSGSFRRTPLVLT
TRPSCYSSCSSSSEFELPESGTCEDDAYVSKLRSPHVYEQEEGIVGLRKITKSSVDSRAS
LCSPRLLSALRSLITSKYTDIQVNSVAALVNLSLEKVNKVKIVRAGFVPPLIDVLRGRFP
EAQEHACGALFSLALDDGNKTAIGVLGALQPLVHVMMRSESERARHDAALALYHLSLVQS
NRLKLVKLGTVQILLNMVKLGQMSGQALLILCNLGAFSEGRAAMLDAGAVEFLIDMLRKD
KFDSESTQESCVAVLCALSHGGGLRFRGLAKLAGAIDVLKDVAEKNSRERAKEKARRVLE
LLKAKEEEEEDVDWEKVLESGFPGRATTGQSSRNSTEF
>Sgl63875 E3_adaptor/Cullin_RING/BCR/BTB 53.6 0.0
MKSSKKGKKQNTKKLGLNTTHLSTLHQRLYHGFNLAFRYSNDKRREWYTNDVEIQRMVAR
SISSFLDGTSPETWNMPIVKDSIPDVVKAIGGILQSPNEVVVALGSEVTVKLVKILPTLM
LRPHFGHLCNSLTPLLSRRQSHVAAMSATALNIIVSNLSVNKEKEVWEILEKHDVISQVV
GNLRAFCDEVKPIEYFVEMASLLSSIMQLWPPSRYPVWNDAQLMEVVEVLCNKPEATVKV
AVLQFYSALALCANGGQRLLENGNFLIQTVVQCMGESQPLSLRISAFKTARYLMATKKLC
SEVLILSCEPIIKSIICALTISSMHPVKFSSQEETLMLEACHLALITRWSGKHHNFFWRL
RGDKVLAHLLVRNLQNLYPHQQSLSVEELIKVTREGLAANFHLDMRPYVWEIIGWLSAQC
EEDFSPNKNDHCLRILVATACLAFVDSIGRERLLRQGDRKYTLRSISAAKATLMMLYSPC
KYISSEAKLLLLEVLRSDGEEYLKQLLHALDFVYSGDMSRKPDKAQIFISLVGLTCYSGL
PRFCKKVVRNGGIKTLLGYIKWWIDNVSHTEKVCLTSHLKVTSMERTCCIIDAEDWEGNE
AHLILALWSLAELINSHGMEGCELDIFSRQKIYEKEQFIQDIQQISVDSTCTGLRWYCSY
LLSLFGYYGFPSKLGKSIASFCEKDYGDMRLVLRDGQYLNVHQVILLIRCPSLLPGYPSD
EEKMSKSNNSPARQVTEKCRTKEVTLSAQVDQEAMSKLLDFVYSGYLQAQGAIVKKLRLL
AKHCNIQPLLHLLCRKRPKREVPVPRFDLTTALGPIGHEFSDIMLEAKSTEDTGRVCSCC
YHSMPHIHAHRAILSSSCDYLRALFQSGMQESRSESLKVPVSWEALCKVVIWLYSYNLPK
PVSGCLWANMDVQQKMLELQPYIELCWLGEFWFLDDVKEECSSLITSSLDSPTLAIKVIK
VAAHFTQWELVNVAANKIAPFYRSLHSSDALDVLDEALVEIIRLASVQLAQESV
>Sgl63885 E3_activity/RING/PHD 38.6 23.1
MKLTELESPTIMAAKPSSSSSSSSSSHHHHNHSQNHNNSITTNNHNHNHQPLSIDLNEVP
SFSETLINLSPTSVVRSIHDVPKYAEGVAAEIPDDAGPCAGCGGGLTDVERLVCDGCERA
FHFACSGVASLGVEDWVCRVCVSEGVSSRRWRLGRKDEGGVRLLDMNASPPSDCDAGEAL
AVAAAAAGAASGSGSRQLCFGDNTFGGNASGGLLSYPNLICSSNGFGFQKEPTVVAHKLR
LDFQDILQSKWSTARNFDDIKHGSQLGRLRSTGTTFRLPSWNSSEVLQSLREFISERHGI
LDEGWRVEFKQSKNGCESYAVYCAPDGKVFETMSDVANYLGLVSNGNPLEPETRSDYGST
LRKNGLNPPKRRKLTKIPTGNGFMESKDSLMSGCKDGFFSNLQKESFMSKDEKKVEVTEG
VQEENDVNDLHHFHEGLPLQYEDFFVLSLGKIDARSSYHDACKIWPVGYRSCWHDKITGS
LFLCHVLDGGDSGPVFKVRRFPCSALPIPYGSTVLQRQRGICLNNPGKAGEKSTPSEEES
CIAMLLSDPCFSPEDDSMSWLLSSPNEVVGQKEIRSSHEVNSTCDRSQDLLAHNSPTGEK
IGEFSVDGRSSSIVWSILSQKLADACRQTYKQKGSLKFFCKHVEDGMSSFYDIMTCRNKG
VFSSLDKFCSLLGSLKVPLVVTSDDELDPTIEALKNWLSLDRFGLDVEFVQELIEQSPDF
RRCLHYESLRKRSDCSTAPLVRNGLLLINGKSMEQCKQDISLYGCYKEYRTIEEPDSSIH
IRPPGNSVGAKLPPHLVGDVLQVWELLHRFHDVLGLEPQNFNELEVELISPWFESLPQHG
SCERDSPVIHGPGIPSEHRSSSSDIAVLEENRFIEMQSAAVREHAHASLAFSTDNNCSNV
SLRKAHMSLLDVIVSELQIKVAAMVDPSIDAESKSRRGRRRDVDSSILAIRPKLNLLPIN
ELTWPELARRYILAVVSMDGNPDSAETGIRECGKVFRCLQGDGGVLCGSLVGVAGIEADA
LLLAEARKRIYGCLSSGNDQLIMEDDNAEPVGASGTMNSGEGKIPEWAQALEPVRKLPTN
VGTRIRKCVYEALEKNPPDWARKTLERSISKEVYKGNASGPTKKAVLSVLVDVLNECSQQ
KVLEERKRTTIVSISETIMRKCRILLRRAASADDEKMFCNLVGRNLIHSSENDDEGLLGS
PGMVSRPLDFRTIDLRLAFGAYSGSPESFLEDVRELWKNVRVAHTEQPELVQKAERLSEN
FETLYEEEVVALVDKLKEYSEMEQLTAEAKKEIEDILASTSNIPKAPWDEGVCKVCGIDK
DDDSVLLCDTCDAEYHTYCLNPPLARIPEGNWYCPSCVFGVNMLESSSKGIPFMGQRHRR
KNHGEGIRSYLEELARLATVIEQKEYWEFSVEERILLLKFLSDEVLNSILIRQHIEQCFE
TSADLQQKLRMLFSEWKSLKVREDILATTATCTELQPTVTERCDQIHSVSDKAQVRGDTG
FLQSTNHISSQNVKHMEKINSSETHVKQLVDSGCQMKDPVEVVNKNVASVKKDEHERSSK
RLKKSSQKKDCSDLDAIPPETSVMDSESCQDKKHEHGMPDVPAVCRSEDMHGVTVSSCPV
KSGSAEDVSCPTSTVLQASNLELSAVQNELSALHKSIANAESQLMKSSVRMDFLGSDALG
RLYWASSLPGAHPRIIVDCTISNQHTTQHGGHARRGGEGIFFETSSSISNSQEGSSVSCP
FVYGHDCSRPSSSQWVYYQSQEEIKELIKSFKLKNPKERELKDSILNWQKLRCHELHQTG
IQEKIPPSVSVSVEENNATGLITRADTHLEHKYGPFCQEDSMGDAKKQSRRSRGTSDEKL
LRCKCLEPIWVSRHHCLSCHTTFYTMEELENHNSGKCTSGSAVPEKRKGSEEPARGKIMK
KSEARQHLGMVTDKSQASKGADSALSRHIRFQNEGLLCPYKFDEISSKFVTNDSIKELVR
GIGLLGSEGLPSFVPSGSPYLSDPTLRIVFPKLDIAADVDQCQNPEESVPFTGKSRAGTV
VDSGSQRVLETKTDEDSEKGLPLPGIRHEKSKKSLARNFTVTDLYCTVPESSFKPVVGRA
AQILRQLKICLLDMEAALPEEALRQSKVHAEKRRAWHAFVKAAETIFEMVEATILLEDMI
KSEYLKNERWYWSSLSAAAKTSTMSSLALRIYALDNAILYERSVSDLTSAGSLKPNTDVD
QQSPSNLDSSDKKASNLDSSDKSKPSNLDSSDKSKPSNLDSTDKSKPSNLDSSDKSKQGR
RMSTRRRRDAEG
>Sgl63936 DUB/USP 209.9 0.3
MADSQNDTNNGAPTLRVSVKWQKKVFPEVEIDTSQPPYVFKCQLFDLTGVPPERQKIMVK
GGLLKDDAEWPTAGVKEGQRLMMMGTADEIVKAPEEGTVFAEDLPEEEQVANVGHSAGLF
NLGNTCYMNSTIQCLHSVPELKSALLEYTQSQSGRNNELDQTSHLLTVATKDLFNELDKN
VKPVAPMQFWMVLRKKFPQFGQLHNGSFMQQDAEECWTQLLYTLSQSLKSPDTSESLSAV
KRLFGVELTSRVHCQESGEESTETESTFALKCHISHEVNHLHEGLKHGLKSELEKNSPAL
GRSAIYVKESRISGLPRYLTIQFVRFFWKRESNQKAKILRKVDYPLELDVYDLCSDELKK
KLEVPRQILRDEEGKKLGLKPSEKSSVSKDGDVKMLDAEGSSVGGGESSTGTSQEVEKEV
QFTGVYDLVSVLTHKGRSADSGHYVGWVKQDNGKWIEFDDDNPIPQREEDIVKLSGGGDW
HMAYICMYKARVAPI
>Sgl64217 E3_adaptor/Cullin_RING/BCR/BTB 47.8 0.0
MSVDESLRSVSLDYLNLLINGQAFSDVTFSVEGRLVHAHRCILAARSLFFRKFFCGGEQG
GGGVMGQACSPRSGGGQGQGQGQVIPVNSVGYEVFMLLLQFLYSGQVSIVPQKNEARPNC
GERGCWHTHCTSAVDLALDTLSAARSFGVEQLALFTQEESPLPRPKSPPYRAMPGRPSTK
KRKKQPGEDDEKKEVQRAKKQNQCGKCAGEVLTDINKLHKKLQTNPEVVEKPGDMSLSKL
KNLYNHAKELAETEVRVSNILLAQLDALLPPEPPVQQRRRLEGNEQKKKQKKNDSDISRV
SPSMRNQLDNHATLKGEQVAARLPTEECDKDEYIVVKVIHYDRETREFEVLDEEPGDDEE
GGGQRKYKLPPSHIIPFPKRNDPSIALDFPPGRAVLAVYPGTTALYKATVVNPNRKVFHI
ILIVWISICFFNRTM
>Sgl64400 UBD/Alpha-Helix/UBA 27.4 0.0
MNKLRGNRDKVQQFMNITGVSEKVAQQALKAGDWHLEGALDIYYSQPQIKSLPDSRYLEE
LFNRYRDPNGDIINADGITNLCNDLQVDHEDIVMLVMSWHMKASAMCEYSKQEFIGGLQA
LGVDSLEKLRERIPYMRSELKDEQKFRDIYIFAFGWAKEKGQKSLALDTAIGMWQLLFAE
RQWPLIDQWCQFLQDRHNKAISRDTWAQLLEFVRTVDPQLSNYDAEGAWPYLIDEFVEYL
YENGIFQRG
>Sgl65242 E3_adaptor/Cullin_RING/BCR/BTB 27 0.0
MMGGNQIVPKDTVTFNVGGKIFQTTSTTLANAGRNSFFGPLFDDDWNLHSSNSNSSPMSH
DQVMFIDRNPECFGVLLDLLRTGELYIPPHLPEKLVFREAEFYGVSDHVRGAKWGPFEGN
RLSLTRSVKGRAPGDGTAIRGGPDGGCCVAHGCIVHVYDWMMEERPPLNLDYQIVNDVGW
LDANHVVVSACERLGRGDGGMGVFNAANGELRHKFQVQHDNQPKTFTAGALAFTSESESK
MIYCSCKGRSNEYGVGVWDQETGQQVDFFYEPLGWSLGDADRLQWLPGSNCLLVSTLFPR
KDNCYISLLDFRAKSMVWSWSDIGHPNPNPNNPVLVDEKRVRDAIGMEDSSSICVVNEFE
DLGFIDLRSSASSVRWSSRSRLVNVMKANNRTSEDDEPCYPKLAFHNSQLFSSMNDSISV
FSGPDWVLTSRLRHPDGGPICDFSIAGDRLFALHSELNIFDVWEAPPSPHF
>Sgl65244 E3_adaptor/Cullin_RING/BCR/BTB 26.7 0.0
MMGGNQIVPKDTVTFNVGGKIFQTTSTTLANAGRNSFFGPLFDDDWNLHSSNSNSPPMSH
DQVMFIDRNPECFGVLLDLLRTGELYIPPHLPEKLVFREAEFYGVSDHVRGAKWGPFEGN
RLSLTRSVTGRAPGDGTAIRGGPDGGCCVAHGCIVHVYDWMMEERPPLNLDYQIVNDVGW
LDANHVVVSACERLGRGDGGMGVFNAANGELRHKFQVQHDNQPKTFTAGALAFTSESESK
MIYCSCKGRSNEYGVGVWDQETGQQVDFFYEPLGWSLGDADRLQWLPGSNCLLVSTLFPR
KDNCYISLLDFRAKSMVWSWSDIGHPNPNPNNPVLVDEKRVRDAIGMEDSSSICVVNEFE
DLGFIDLRSSASSVRWSSRSRLVNVMKANNRTSEDDEPCYPKLAFHNSQLFSSMNDSISV
FSGPDWVLTSRLRHPDGGPICDFSIAGDRLFALHSELNIFDVWEAPPSPHF
>Sgl65285 ULD/UDP/UBQ/UBQ_Other 31.8 0.0
MKMNKGKGPSLKRQSSTSGGASGGGAEEVTIDLTDQMLYLDIERTTGGRVKGSRSVLQKQ
KDACRSQPPVFTCRVETVGVVVSNFGDLEKQWVVDMGFGGLLYLQGKRLPRALCYWLMSR
FDPVTRTLFLSGSWAGSGCIELPINVGQVHWVFGLPHGDKKVPISKKFTERVKCLKEDLL
AEFGEQHQDGSRVVAMKNVVDRVEGNWRQEEELVFKTYFLILLLGDFIAPTTSARLSPDL
FTAVACVHNTNEYDWCSLLLDRLCEAGKKFAKNFYRDGFAKTCGGCTYFLAILYLDHLNI
QPKSWGMFPRLKAWSNDDINKVKLDDRFPSEDGKPRKGDFGKTPCFDGAYGEGHPRLGRD
SLGPHGGLDQVASAVVRAMGCQPDYEGMGACEKVGADALVDDGILPNPPRAKRRAPPVSS
NPYLRTLAKRKKEGGQAGLDFGSSQTKKMNDQCSELSPNKEDGRSKKSDENENVTFEHEA
LSESNATGGDNIHLNTDGGAVDVQPSQELAATTGGELGADESMKQVGNIVDELKKTMQEE
GEEISDSIIVSKVNELNKELQQREEEGQNTIHRSRSPEVEGEPLSRQSLESKDDANDCAS
VESKCSEAKNLTILQCGHMYASVPNCYTVLGTDGPGVDDNYIRAAAPLYTRMWKRTYVDR
SVRYMMDPMFAMRVDQERGLSSDTWESTTKRAASLSLPSRLWRRRCVRIVCSYRDLLGQS
RPQMDRWECPQLANKGSEDGGPRRRRSHINEEREWLLTDDLMNDLNEANALQKYATEKEV
EVDDLTLQLRRRFVHPDSTPAGNNMLHGDILTVMHKTGQLLSWDLLSDSRDYRLCTLQDL
CTEVFVTDMRVHLDDPVKVVRKQWEEITGVSWKNIMVYYEGKLIRAKTTFRDIGLKDGDA
IFMVGKTVFTKIGTV
>Sgl65314 E3_activity/RING/RING 34.3 15.9
MSSDNNNNNNNTTTSTSTFSFPQQSQQQQYFCYECNRTVSITPSSSSSELLCPNCNGGFL
EEVENPNPNPQPHPHSQFSSIFAPFLSPPPSSSSSAADQLAPFAPFFFPPSSASSSPLDP
VDLSSIFGAGNLNPNSNPNNPRSPFHDSDVFNPFQFLQSYLQTMRAGGANIQFVIENDQP
GAGSGGGGGGGNFRLPSNLGDYFFGPGLEQLIQQLAENDPNRYGTPPASKTAVEGLPSVK
VDQELLSSDSSQCAVCMDEFQLGAEAKQMPCKHVFHGDCILPWLELHNSCPVCRHELPTD
DPDYEQRSRGRRENPGSGGNGNGNGNGDGGMDEALQNEIVERRFRISLPWPFGGAAEGNN
ASGDGGNESNPRRRENPDFGSETRQEDLD
>Sgl65340 DUB/USP 260.2 0.6
MHVSSFSSTLSLDPNPNTWNSVLQILITVFVLLLGFLYLLRSTASKYFVVDTNFNTSSSS
SSSSSDMAVANSNCNSAIEACANCGNPTSKQCAGCKRVKYCSQSCQSKHWRSGHKKRCQE
LKHSGKENVSITSASSTSSGTDKTQKVVDKVLFPYDEFVKFYDWDKPIFPPCGLLNCGNS
CYANVVLQCLAHTRPLLTYLLERGHRRDCRRNGWCFLCELETHLTRASRNPQPFSPLNIL
SRLPSIGSNLGYGRQEDAHEFMRFAIDAMQSVCLDEHGGEKVIDPKSQETTLIQHIFGGQ
LRSQIICTKCNQVSNQYENMMDLTVEIQGDATSLQECLDQFTAKEWLHGENMYKCDGCKD
YVSAWKHLTIHQAPNVLTIALKRFQSGRFGKINKKISFPENLDLSPYMSEERDGTDKYKL
YAIIVHVDMLNASFFGHYICYTKGFQGDWYRIDDCKVTRVELEEVLLQGAYMLMYRRISA
RPKCLKTFGTTINQQQNGDTLSTGAEHNNTIQHDDLTKLSSSNCSSVNLASDVNGQVDHP
HAPAVHLSRALGDSSILTVASAEVPVKVADIPGSSTLGANALDETSCDLMGATTNQQKNG
EMVSIGAEHSSTIQLDESLKLSSSNCSSAYPASDVNRPLDHLQTPVHLLRALGDGNGFSN
TLSVASTEVPVADIPGSSSCEGSATAVNGISASPGKHLDAESFAPAIINQTTACCERNDS
KLAYLGLGKKEAEVYSDDIEVETVEVNESDGQSNSVLDDMTVD
>Sgl65426 DUB/USP 233.4 8.5
MHVSSFSSTLSLDPNPNTWNSVLQILITVFVLLLGFFYLLRSTASKYFVVDTNFNTSSSS
SSSSSAMAVANSNCNSAIEACANCGNPTSKQCAGCKRVKYCSQSCQSKHWRSGHKKRCQE
LKHSGKENVSITSASSTSSGTDKTQKVVDKVLFPYDEFVKFYDWDKPIFPPCGLLNCGNS
CYANVVLQCLAHTRPLLTYLLERGHRRDCRRNGCNLGYGRQEDAHEFMRFAIDAMQSVCL
DEHGGEKVIDPKSQETTLIQHIFGGQLRSQIICTKCNQISNQYENMMDLTVEIQGDATSL
QECLDQFTAKEWLHGENMYKCDGCKDYVSAWKHLTIHQAPNVLTIALKRFQSGRFGKINK
KISFPENLDLSPYMSEERDGTDKYKLYAIIVHVDMLNASFFGHYICYTKGFQGDWYRIDD
CKVTRVELEEVLLQGAYMLMYRRISARPKCLKTFGTTINQQQNGDTLSTGAEHNNTIQHD
DPTKLSSSNCSSVNLASDVNGQVDHPHAPAVHLSRALGDSSILTVASAEVPVKVADIPGS
STLGANALDEISCDLMGATTNQQKNGEMVSIGAEHSSTIQLDESLKLSSSNCSSAYPASD
VNRPLDHLQTPVHLLRALGDGNGFSNTLSVASTEVPVADIPGSSSCEGSATAVNGISASP
GKHLDAESFAPAIINQTAACCERNDSKLAYLGLGKKEAEVYSDDIEVETVEVNESDGQSN
SVLDDMTVD
>Sgl65587 E3_adaptor/Cullin_RING/SCF/F-box 12.1 0.1
MADLCKSKPHQCPYICDELLREILSRLPIKALLVCQSVCKNFRKIVHELQEEIIMTDPQS
LPMFGFLTADHIYFTKYVGIETGEIVNLPRNTSNGETNVVISSGYDKGLLAGFSLDLSAL
TDNVFRKTNSGQFREFFYTMHQGLLLLSYFNGTYEVRNPVTKQSYVVTTKKGQYDGLLTI
GMVVTFPTLPGSKCEFMIVRLSERLNSLEIYCSEMCSWERSELEVLGENNLLRNDTVNQL
TWENYVALVDGLDVITLYLLTENNVVAIKFRGKNPPKITDQYVIPLPQGVKGNRLQVNIW
DCGGTLFLTDFTRFNKLRMWKHPKDYCSTQADACAWTPLVRIATRITMQIKASYGGSRPG
LPIRLIGCNPDVGVMYFFIRPFVLAYDVTNDTLHKIAADDMYIPMSAVTVRGCFPLKPCF
SSLDALK
>Sgl65769 E3_activity/RING/RING 36.2 5.6
MEAAMMQNKLTKLHSDQSDGNMPVDTSDDANCMLERGRMEYGCHHYRRRCRIRAPCCNEI
FDCRHCHNEAMNNIKLENTKRHDIPRHQVQQVICSLCGTEQEVRQVCINCGVCMGKYFCE
TCKLYDDDISKKQYHCEGCGICRIGGRENFFHCYKCGCCYSVVLKNSHPCVEGAMHHDCP
VCFEYLFESRNDVTVLPCGHTIHKNCLKEMQEHYQYACPLCSKSVCDMSKVWEKYDMEIA
ATPMPEPFQNKTVSILCNDCGSKSCVQYHIVAQKCPYCKSYNTRQLSG
>Sgl65784 E3_activity/RING/RING 33 9.1
MALRFAEYQGKNQTEKYPLLMDPERRNENEHVIDIRRSVEASSSGTTHDRISSELDSTQP
EDRPSSSARASISQLSLPLSNLSNSRNSSFSRRGNAHSRRRRSPLNSGLWISVELALTLA
QIVASVIVLSLSRHEHPRTPLFTWIVGYASGCVATLPLLYWRFLHRNQASDQDTSQSRQP
SSNGNRTQTVEDENNTNTFNRSMSGQSSGLHNARLKTAIEYFKMGLDCFFAIWFVVGNVW
IFGGHASSTEAPNLYRLCIVFLIFSCIGYAMPFILCATICCCLPCIISVLGFREDLNQTR
GATTESINSLPTYKFKLKKGRHSEGGGESGVVAAGTEKERVISGEDAVCCICLAKYANND
EVRELPCTHLFHKECVDKWLKINALCPLCKSEVGDTLLSSLAEATASLRRAENRVVSS
>Sgl65799 E3_activity/RING/RING 33 9.1
MALRFAEYQGKNQTEKYPLLMDPERRNENEHVIDIRRSVEASSSGTTHDRISSELDSTQP
EDRPSSSARASISQLSLPLSNLSNSRNSSFSRRGNAHSRRRRSPLNSGLWISVELALTLA
QIVASVIVLSLSTHEHPRTPLFTWIVGYASGCVATLPLLYWRFLHRNQASDQDTSQSRQP
SSNGNPTQTVEDENNTTTFNRSMSGQSSGLHNARLKTAIEYFKMGLDCFFAIWFVVGNVW
IFGGHASSTEAPNLYRLCIVFLIFSCIGYAMPFILCATICCCLPCIISVLGFREDLNQTR
GATTESINSLPTYKFKLKKGRHSEGGGESGVVAAGTEKERVISGEDAVCCICLAKYANND
EVRELPCTHLFHKECVDKWLKINALCPLCKSEVGDTLLSSLAEATASLRRAENRVVSS
>Sgl65815 E3_activity/RING/U-box 104.4 0.1
MEVSLWRALLHNISSFFCLPSHENFDSATVQKSFLKMEEILKLLKPILDAVMDTEVASDE
LLNKVLEELGRSIDESRYLFEGWYPLASRVDLVLQAESLTVRIRDCVLEFFWILNDSRQS
LPMELSSSSLEHCIQKAKNIGCDTTSTIINDAVQHDQEGAHGPSPDRLVKIADCLGLRSN
QEILIEAVALEKLKENAEQAEKNAEVDHFEQLISLVMRMHDRLVMLKQSQSCTPIPIPAD
FCCPLSLELMTDPVIVSSGQTYERAFIRKWLDLGLTVCPKTRQSLVHTNLIPNYTVKALI
ANWCEINNVKLPDPMKCINEDQSIALLSHDDGSLRNSQINSHSKGNHVESPESMRSAGLE
GKTVSYSSDLHRERASPSHPRSSSDNSMFCMVEKEHGLDVGRVSLEERLSSSERKSVDLN
GQHHVPSARREYANGVSSHEQLSERNDGTSLDGNRDSEMNLAERLSGDADQISQSPGDSR
DASGELSNEPHASSLESTSRREPGFLPRLMDMKSRNQNIWRRPSDRLVARIISSPTTESR
PDLSETETEVKKLVDDLKSDSIETQREATAQLRLLAKHNMDNRVVIANCGAISLLVDLLR
STDPKTQENAVTALLNLSINDNNKTTIGNADAIEPLIHVLQTGTHEARENSAATLFSLSV
IEENKSKIGRSGAIGPLVELLGNGTPRGKKDAATALFNLSIYHENKARIMQAGAVRHLVE
LMDPAVGMVDKAVAVLANLATIPEGRAAIGQAGGIPVLVEVVELGSARGKENAAAALLQL
CTYSTRFCSMVLQEGAVPPLVALSQSGTPRAREKAQSLLSYFRSQRHANSRG
>Sgl65816 E3_adaptor/Cullin_RING/DCX/DWD 76.9 13.2
MAQTNWEADKMLDVYIHDYLVKRDLKATAQAFQTEGKVSSDPVAIDAPGGFLFEWWSVFW
DIFIARTNEKHSEVAASYIETHAIRARELQQQQPQQSQSQQPPNLQQQQLQMQQIFMQRH
AQQQQQQQQQQHQQQPQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHQHPPQPQRRD
GAHLLNGSANTNEVSGNDSLARQNCGTANSMATKMYEERLKSPLQRDSLDDAALKQRFAD
NVNQLMDQNHASILKSAAAGQPSGGQILHGTSGSMSQQMSSRNQQLPGSVVADIKTEANP
ILTPRAAGPEASLIGIPGSNQNGNNLTLKGWPLTGIDNLRSGLLQQQKSFMQASQPFHQL
QMLSPQHQQQLMLAQQNLTSTSANDVESRRLRMLLNSRGMGIGKEGLPNHVGDMVSNAGL
PMQAGCPVLPRGGDADMLLKLKMAQFQQQQQQQQNSNQLHQLQQNALSGQPSQVSNPSLH
QPEKIGGAASINMDGSLSNSFRGNDQAAKNQPGRKRKQPLSSSGPANSSGTANTAGPSPS
SAPSTPSTHTAGDVMSMPSFPHGGNSSKPALMFGADATGTLASPSNQLADMERFVEDGSL
DDNVESFLSHDDADPRDPVGRGMDLSKGFMFTEVNSARGSTAKVVCCHFSSDGKLLATGG
HDMKAVLWHADSLKPKATLEEHTKLITDVRFSPSMSRLATSSFDKSVRVWEVDNPSYSLR
NFTGHSATVMSLDFHPNKEDLICSCDGDGEIRYWSINNGSCTRVFKGGSTQIRFQPRQGR
YLAAAAENIISILDVETQACQHRLKGHSKQIHSVCWDSSGEYLASVSEDSVRVWSFGLGN
EGECVHELSCNGNKFYSCAFHPSYASLLVIGCYQSMELWNMSENKTMTLSAHDGLIAALS
VSSVTGLVASVSHDKFVKLWK
>Sgl65847 E3_activity/RING/U-box 104.3 0.1
MEVSLWRALLHNISSFLCLPSHENFDSATVQKSFLKMEEILKLLKPILDAVMDTEVASDE
LLNKVLEELGRSIDESRYLFEGWYPLASRVDLVLQAESLTVRIRDCVLEFFWILNDSRQS
LPVELSSSSLEHCIQKAKNIGCDTASTIINDAVQHDQEGAHGPSPDRLVKIADCLGLRSN
QEILIEAVALEKLKENAEQAEKNAEVDHFEQLISLVMRMHDRLVMLKQSQSCTPIPIPAD
FCCPLSLELMTDPVIVSSGQTYERAFIRKWLDLGLTVCPKTRQSLVHTNLIPNYTVKALI
ANWCEINNVKLPDPMKCINEDQSIALLSHDDSGSLRNSQINSHSKGNHVESPESMRSAGL
EGKTVSYSSDLHRERASPSHPRSSSDNSMFCMVEKEHGLDVGRLSLEERLSSSERKSVDL
NGQHHVPSARREYANGVSSHEQLSERNDGTSLDGNRDSEMNLAERLSGDADQISQSPGDS
RDASGELSNEPHASSLESTSRREPGFLPRLMDMKSRNQNIWRRPSDRLVARIISSPTTES
RPDLSETETEVKKLVDDLKSDSIETQREATAQLRLLAKHNMDNRVVIANCGAISLLVDLL
RSTDPKTQENAVTALLNLSINDNNKTTIGNADAIEPLIHVLQTGTHEARENSAATLFSLS
VIEENKSKIGRSGAIGPLVELLGNGTPRGKKDAATALFNLSIYHENKARIMQAGAVRHLV
ELMDPAVGMVDKAVAVLANLATIPEGRAAIGQAGGIPVLVEVVELGSARGKENAAAALLQ
LCTYSTRFCSMVLQEGAVPPLVALSQSGTPRAREKAQSLLSYFRSQRHANSRG
>Sgl65848 E3_adaptor/Cullin_RING/DCX/DWD 76.9 13.2
MAQTNWEADKMLDVYIHDYLVKRDLKATAQAFQTEGKVSSDPVAIDAPGGFLFEWWSVFW
DIFIARTNEKHSEVAASYIETHAIRARELQQQQPQQSQSQQPPNLQQQQLQMQQIFMQRH
AQQQQQQQQQQHQQQPQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHQQHQHPPQPQRRD
GAHLLNGSANTNEVAGNDSLARQNCGTANSMATKMYEERLKSPLQRDSLDDAALKQRFAD
NVNQLMDQNHASILKSAAAGQPSGGQILHGTSGSMSQQMSSRNQQLPGSVVADIKTEANP
ILTPRAAGPEASLIGIPGSNQNGNNLTLKGWPLTGIDNLRSGLLQQQKSFMQASQPFHQL
QMLSPQHQQQLMLAQQNLTSTSANDVESRRLRMLLNSRGMGIGKEGLPNHVGDMVSNAGL
PMQAGCPVLPRGGDADMLLKLKMAQFQQQQQQQQNSNQLHQLPQNGLSGQPSQVSNPSLH
QPEKIGGAASINMDGSLSNSFRGNDQAAKNQPGRKRKQPLSSSGPANSSGTANTAGPSPS
SAPSTPSTHTAGDVMSMPSFPHGGNSSKPALMFGADATGTLASPSNQLADMERFVEDGSL
DDNVESFLSHDDADPRDPVGRGMDLSKGFMFTEVNSARGSTAKVVCCHFSSDGKLLATGG
HDMKAVLWHADSLKPKATLEEHTKLITDVRFSPSMSRLATSSFDKSVRVWEVDNPSYSLR
NFTGHSATVMSLDFHPNKEDLICSCDGDGEIRYWSINNGSCTRVFKGGSTQIRFQPRQGR
YLAAAAENIISILDVETQACQHRLKGHSKQIHSVCWDSSGEYLASVSEDSVRVWSFGLGN
EGECVHELSCNGNKFYSCAFHPSYASLLVIGCYQSMELWNMSENKTMTLSAHDGLIAALS
VSSVTGLVASVSHDKFVKLWK
>Sgl66003 E3_adaptor/Cullin_RING/SCF/F-box 13.4 0.0
MVILTETRVGPDNTQAILRKLPFDQHVMIEPVGYSGGVLVLWNSSLIDFSVIKKETQSIH
GFVKVLNSDFTFFLSAVYGNPKHRLRKLLWHELCDFLPVVNNANWLVMGDFNQVTHSHEK
FGGRMPSSSRMNEFLSCIHHCNLLDVGYEGPKFTWSNKRRRGPIMERLDRALFSPSWLTA
FPDAFLTHLPRISSDHAPILFRNTRPASSPLRGTPSFKFEPMWCMDPSFLPLIQNSWETT
SGPFHQRMSALSSNIQTWVKDIFGDLQKKKKELSARLLGVQKNLCLYPLSSYLQELEDSL
SNELSTLLLQEEQFWHIRSRVNWLSEGDNNTGFFHKSVQVRRKTNRITALSSAVGELLTE
PDQIQQHITSFYRVLFSTERNEVEWPLQPISHLPVQSPPISVASVPTAAEIEEAVFQSNP
LKSPGPDGFHSFFYQKFWHVLSTDIVRFIQHTFYTTSIDPSINHTNVALIPKVQNPSSIK
NFRPISLCNTVFKFITKIILNRLKSLLPAMISPNQNAFLKNRGADTNFIVASEILHSMKT
KKGSKGFFAFKIDLEKAYDRLEWDFIKTSLLSHNFDERSVNMIMSCIASTSTSILVNGSP
TAPFLPSRGIRQGDPMSPYIFILCMEWLSKLIEEECDKGNWKPFKFGQSGPRVSHLLFAD
DLILFGEADERTLLSLTSTLDLFCHASGQLINSSKSTLVFSKNTDPFLIELFEAELNCSQ
TGSLGPYLGFPLKDRKPTALDFNYLIDKTRNRLSQWKANFLSKAGRTCLIKSTLSSIPAY
TMTCINLQQSVIQKMDSIACNFFWGKDGTKQGIHLVAWKDICTPKPLGGLGIKNLKGFNH
ISLVKLCWKLVTCPTNLASEVIAAKYVFNRGNPYSFNKGSYIWKGLKEAWSDFTNNCRWV
IGNGNNTSVWYDTWASAIPLRTLFVGPLTLNHSLMTVSSLIQASQWNTDPLRPFHFLEDR
LFRTIQSLPLPWSDMQDRPVYLHLKQGKFWFRKAYEEWCTKSLTHDLVPQSIWSSFTIPK
IKVFLWLASKNRLPTRFNLFQRSITSSMFCPFCPNIAETAIHCLRDCPNALEIWEECGVD
NTFFATSGHDWLDQNLSNASAVQGLPWKIFFPFMCWSIWKKRNSWIFKLKNINKVECRKQ
ACSSAWEFYSNLPQPRPVNPLAQGTQRLLPSNLLHFINVDASWNSLTKVAGLGGSIRDDH
LIWVGGFQATCLANSSLLSELFAIRWALSMIVQKEWTDVGVFSDCQVMVNLINDKAVVSH
EYILLIVECRELLAQSSGSLLQFIKRTHNMVADSLAKKAVDFCGALNTHRWLEDPLPGST
EALYQDMMFLSTMINVNSNGNLRINIQQVMDPVETNCKLPEDLFRDILSRLSVRDLLRFR
SVSKSWCALIDDPSFILTHHFIQYTIHKANGDVPLLLWRHTGSIRGYQIECYLFFKQQGY
DTFTNWTSDVERYAHSVFPTNSDINLSIFCRGSANGIICLDFQGIDLKVKRRDFYYISLW
NPATRDFKIVVYPHVADQRMPGQFVVVGFGYDPVTNDYKIVATTVVTSDIVLAYMVYTLS
TNSWKRVSEPSLFGKTASVRCSLMDSCLNGVYYWTAHLLNNTEDKIFRILSFNFSTEAFI
FSDPPQEALPPVYLMGNEFYWNIGLYNERLALFLIHPALDTPEASADIWVATEFDDEFGV
PVAWQCLISIKPIFERIGSTFGAQWVDGDIVFELYPDEFSLYNPTTGKFRRLGISFRQCF
SYVESLFPLSR
>Sgl66047 E3_adaptor/Cullin_RING/DCX/DWD 122.2 18.3
MKLAGLKSLDPAHEDSIWAATWVPATDTRPYALLLTGSLDETVRLWKADDDVVLERTNTG
HSLGVVSVAAHPSGVIAASASLDSFVRVFDVDTNNTIATLESPPSESWQMQFDPKGTMLA
VAGGSSTSIKVWDTATWKLVATLQIPRPESSKPSDKMATKKFVLSVAWSPDGRRLACGSM
DGTVSVFDVMRSKFLHHLEGHLMPVRSLVYSPSDPRVLFSGSDDAHIHMYDAEGKSMIGS
LSGHSSWVLSIDASPDGAAIASGSSDKTVKLWDLGMRAASQSMTNHTDMVWGVAFRPPGG
AGVRSGRLASVSDDKSISLYDYS
>Sgl66065 E3_activity/RING/RING 30.3 4.5
MTWAPTHHHHHVLEPASPPTATMTQGNYDPHVTKSMNVDSNMVVILGVLLFALLCALGLN
SVIRCALGCANQPHHHYNRREGLATYLGPGSRGLKRSTLQQIPTIIYHVANTTTSSSGGN
TVHNYSNNVMSTECMICLGEFIEGEKIKVLPKCKHGFHGKCIDTWLLSSSTCPTCRQSLL
ECAGSGAIVVPVAAVGESYGPHSS
>Sgl66075 E3_activity/RING/U-box 41.7 0.0
MASENLGLVPSQRMENNNLNSQLLFQNSNNPLRFGRGPENPGSKSGYVDDKLFSMDHRER
GYFSPELRRADDGVGGVYEEGPTSERRGRGDRDRTWNHREPASTPSSEEEEDDDEDDDDD
DDDEDDEEGKNSHSSSGVGGANSKDHAPFGSSTRKMMIKDGVILQPASDANRVSTSENEQ
QGRLGNFQKMVTVAEHDGDMYYLQLLHGTEGSSQGQKDLAVDNGSGLNGRKDSYVSSDPG
ESLRAIFSDPITGALMDDAMILPCGHSFGSVGVQQVIKMKACYTCSHSVAEDSVAPNLSL
RAAVQAFRREEDLQMYKASKRRRERFEQEKGNYGDSCFSDLPRGKGVQFPFSVTDRVIIK
GNKRTPPRFVGRQAIVTTQCLNGWYVVKTLDNAESVKLQYRSLEKVQNISSSTPISDKVI
PNWL
>Sgl66083 ULD/UDP/UBQ/UBQ_Other 32.3 0.0
MVGTLPILPLPAPPEDGNLGPTPLSQLPPDHDEKKEVEDQQKSGKPDSVATHALPIGIIH
PPLDISKIVDKTAQFVAKNGPDFEKRIIANNAGNVKFNFLNASDPYHAYYQYQLSELRSQ
NQSTVQQPSSQLDSEAEPVRMVLEPPEAEQYTVRPPEGISHEELDIIKLTAQFAARNGKW
FLTELNSREMNNPLFQFLKPTHSMFMFFTELIKAYSKVLMPPKGLTEKLKNSKADKTVVL
ERCLDRLEWEKSQEQARQKTEDERSQMAMIDWHDFVVVESIDFADDEDESLPRPMTLEEV
IRWSKITTKDDEEIIEPGKEVAMDMDEEDMQLVQEGMKAASLEENEKDKTNEVKADMDED
KDPMRIVKNWKRPEDRISAENDPTKFMISPITGELIPISEMSEHMRISLIDPKYKEQKER
MFTKIRETTLAHDDEISRNIVGLARTRPDIFGTIEEEVSNAVKAEIDKKKDEQPTQVIWD
GHIGSIGRTRIQAMSQSMGEEDEANNDGKPLPGPAAPPRSPVNMPHVPTSNVQYSAQNSA
GLMAPPPPRPMVGVNQMVPPPPSPMQLAPGQQHMMMIRQPMPPGSMNQSDMPVPPAPGTQ
FTPLGVHQHFTPVPPHGMLVGPPQLMSQGMPPPLSPPLEEAPHPLPKEPEPKKQKVDDSA
LIPEEQFLAQHPGPVRINISVPNIDGGNLKGQVLEITMSVNETVGSLKEKISGEIQLPSN
KQKLSGKAGFLKDNLKLAYYNVGDGEMLSLSLKERGGRKR
>Sgl66096 E3_activity/RING/RING 18.9 10.6
MARIKKKPRRSVGGFECGSTSKGNSGENSANPSCNVKSADDDHNNGNIEDTPYFVDVDRS
SWGSIEHKDLSEIVVNNLNFSSEFSGFDLTEELFVRIRLCNVNEYVSRMKLGHWPVIESE
NIYLEFLNKREIDGNKGFDVVVSGKFDGSDEGVTGLVHLVSLKYLTLRPVFGNRLSEGVS
SVRIRVEMLQSAFDACESVVSSSRPVWKKSMMSVMVWLRPEVATSEARYGVDMSSELELS
FYSDVDHSSYECSKFDICRFYEAIKRSKDCAMLDVELPDLLPELRPYQRRAAHWMVQREK
GASEDSAEESLYSSPLNVEVDFLDSHSKMFYNPFSGNVSMREEIPPYVFGGILADEMGLG
KTVELLACVFAHRKPSSEHDSCSRDISDGTEMEKTRPKRLKRERVECICGALSESSKYEG
LWVQCDVCDSWQHADCVGYLPPEDISRTTVGSTGQHNKNKRKKSAADIVMVNGEYVCPIC
SELMQATSSPIESGATLIICPAPILPQWHAEILRHTNPGSLKVFIYEGVKEVSLSKFSAM
DINELVSADIVLTTYDVLREDLSHDSERHEGDRRLLRYQKRYHVVPTHLTRVLWWRICLD
EAQMVETNVAAAAEMALRLHARFRWCITGTPIQRKLDDLFGLLRFLKASPFDVSRWWAEV
IREPYEKKDVTAMTFTHNLFRQLMWRSSKSHVADELELPSQEEHISWLSFSAVEEHFYQR
QHETCVNFAREVLHQIKSDIHERDCLGSFSSVSDPSTIHLEAEKLMNSLLKLRQACCHPQ
VGGSGLRSIQRSPMTMEEVLSVLIGKTKLEGEEALRKVISSLNGLAGIAILQGELFKAAS
LYKEALALAEENSDDFRVDPLLNLHIHHNLAEVLKSASNSSQQVSVCGGQLNRNPEEKPS
DIIGVIGCLDRIEKGQIGTGEDNSERAEDTDKHSEVNCNSSTNGSKGGIKCNIEPHAPHV
SSVESLIDISEGIKRKYLSGFYAKLSQAQQEFQKSYMQVCDSLNDEEVKHNVWWLEALHQ
IEQKKEVVHELSKRIENAVLERTKSPIIASGFRNMTALKFYIQNGLDLLDACRKKVLDQL
LNIDQTMENPNVEDIERVRYCSICDDSNTDGRLCVHCELDKLFQAYEGRLFLRRAKNGKV
ISSSVEVADLRKNTLENNQFYSKQKQNSNNLLSTSSADVVGKGKKGKMYMDSRVSSDLEI
ILGVIRSYFKPDLGEEGVSAANRHLSLFEIMKKEYTQARSLAIVQAQILRAHDETKMAMS
RLRLRDSDDDNSIDALSLEELDSANVINTSDKFVSLDSLSRIRGKLRYLQGLVISKNKIE
SDKEEAQESAVENANKLTAVNEDICPICQEVLQSQKMVFQCGHLICCNCLFKITDRKVGP
NGKLQNKWLVCPTCRQRSDYESIAFADDNHNRSSVGQSENLEASVFVQGSYGTKIEAITR
RILWIKSSDPEAKVLVFSSWNDVLDVLEHAFAANEISYVRMKGGRKNSQAAITSFKEDNV
TNQGIAKIKDQQNPESKFIQVLLLLTQHGANGLNLLEAKHVILVEPLLNPAAEAQAISRV
HRIGQTHKTHVHRFLVKDTVEESIYGMNRNKNSNSFVRNKKNRDQLILTVKDVESLFAVK
PKPSPPSAPDSNNEQNGDLMHLPPSAAAAIAAERRLGQC
>Sgl66126 E3_adaptor/Cullin_RING/DCX/DWD 36.9 3.3
MSSSVSTPQGFVPTSRFGAYEFTNPDPFGDDEPQKNDIDDAELLSVSWNQDYTCFAAGTS
RGFRIYNCDSFKETFRRDLKNGGFGIVEMLFRCNILALVGGGIDSQYSPNKVMIWDDHQG
RCVGEFSFRSEVRSVRLRRDRIVVVLEHKVYVYNFLDLKLLHQIETLANPRGLCCLSHQV
NTFVLACPGRRRGQVRVEHFGLHVTKIINAHESRLACFTLTLDGLILATASTKGTLIRVF
NTMDGTCLQEVRRGTEKADIYGIAFSQNVQWLAVSSDRGTIHLFSLRVRVVGEDESARPI
STPALMHQNSSSSLEPLIAQNTGANPSLSLPFVKGTSHLLGEINGELGFKKRIQGATARG
KLRGAGLVPPDCKAPLRLGVLPKYFSSEWSFARFHLPQNTRCIVAFGSHNTIIVVGLDGS
FYRCSFDPSNGGEMSQLEYVRFLKTEGSPK
>Sgl66132 E3_adaptor/Cullin_RING/DCX/DWD 13.2 0.0
MDGRRISASPRPCSVRRVVAKKRPRGGGVDGFVNSVRKLQRREICSKRDRAFSMSDAQER
FRNIRLQEEYDTHDPKGHSATILSFLRKRSKIIEIVAAHDIVFALAQSGICAAFSRETNQ
RICFLNVSPDEVIRSLFYNKNNDSLITVSVYASDNFSSLKCRTTRIEYIKRGKPDAGFAL
FESESLKWPGFVEFDDVNGKVLTYSAQDSVYKVFDLKNYTMLYSISDTNVQEIKISPGIM
LLIFTKNTSHVPLKILSIEDGTVLKSFNHLIHRNKKVDFIEQFNEKLLVKQENENLQILD
VRNSELTEVSKTDFMTPSAFIFLYENQLFLTFRNRTVAVWNFRDSDDPLSEGTAGSINVS
NILTGKCLAKIRADNCSALEDDSCSKGSGSTSKKRVRASRIRSTPAEALEDITALFYDEE
RNEIYTGNRLGLVHVWSN
>Sgl66141 E3_adaptor/Cullin_RING/DCX/DWD 19.5 0.1
MEWSTIQHLDLRHVGREAKPLQPHAAAFHPTQALIAAAVGKYIIEFDALTGSKISTIDIG
SPAVRMAYSPTSGHVVIAILEDGTIRSCDFDAEQTCVLHSPERKMERISSDAEVHMALTP
LQPVVFFGFHKRMSVTVVGTVEGGRSPTKIKTDLKKPIVNLFCHPRLPVLYVAYAEGLIR
AYNIHTYAVLYTLQLDNTIKLLGAGAFAFHPTLEWLFVGDRRGTLLAWDVSTERPTMIGI
IQVGSQPITSVAWLPALRLVATLSKDGALQVWKTRVVLNPNRAPMQANFFEAAAIESLDI
PKILSQQGGEVAYPLPRVRALEVHTKLNMATLLFAKMASSDNVKNTGFTREGRKQLFAVL
QSARGSSASVLKEKLAALGSSGVLADHQLQAQLQEHHLKGQNQLTIADIARKAFLYSHFL
EGHAKSAPVARLPLITMLDTSNYLSDLPVCQPFHLELNFFSKANRVLHYPVRAFYMEGVN
LMAYNLCSGSDGIYKKLYNSIPGNVVCHPKSIVYSRKQNLFLVLFELGGAENEVVLYREN
TDTRLANSKDSTVKGQDAAFIGPEDNQFAILENDKTGLALYILPGKSSKELDEMNKAALE
ENPTADLAEDAAPNSVKGPVPFMFESEVDRIFSTPLESTLMFASHGNQISLAKLVQGYHL
SGSDGHGHYISTTAEGRKSIKLKVNEIVLQVHWQETLRGHVAGIMTTHRVIIASADLEIL
ASSSTKFDRGIPSFRSLMWIGPALLFSTATAISMLGWDGKVRTVLSTSMPNAVLVGALND
RLLLANLTDINPRQKKKIEIKSCLVGLLEPLLIGFGTMQQYFEQKLDLPETLYQITSRFD
SLRITPRSLDILARGTPVCGDLAVSLSQAGPQFTQVLRGSYAIKALRFSTALSVLKDEFL
RSRDYPRCPPTSHLFHRFRELGYACIKYGQFDSAKETFEVISDYESMLDLFICHLNPSAM
RRLAQKLEEDGADPELRRCCERILRIRSTGWTQGIFANFAAESVVPKGPEWGGGNWEIKT
PTNMKDIPQWELAAEVMPYMKTDDGPIPAIVTDHVGVYLGCIRGRGNVVEVREDSLVKAI
TSTGGDDKPNGTMTSFADSMMSKAAASADPKAASLMGLDTLTKQPSGSAAADEQAKAEEE
FKKSLYGTSGGDSSDDEEGVSKTKKIQIKIRDKPVSSATVDVNKIKEATRQFSLAPPMGR
TKSSAGGSQDFGLNFQPAVTATSTLPTTSNSGSSGDLFGSEALAQPPAVSQPSQAVKGGG
MTAAPIPEDFFQNTISSMQVAASLAPPGTVISKLDQNLQRAGSHPVETSKDNVGFADGGV
PPQATQLPATTTVESVGFPDGGIPPQSAGQTVVQPQVQTTQLQYSSQPLDLSVLGVPPGT
TDSEKPLAQSVPPSSVRPGQVPRGAAAPICFKTGLAHLELNQLPDALSCFDEAFLALAKD
NSRGADIKAQATICAQYKIAVTLLQEIGRLQRVQGPRAISAKDEMARLSRHLGSLPLLAK
HRISCIRTAIKRNMEVQNYAYSKQMLDLLFSKAPPGKQEELRSLIDLCVQRGLTNKSIDP
MEDPSQFCAATLSRLSTIGYDACDLCGAKFAALSAPGCIICGMGSIKRSDSLTGPVPSPF
G
>Sgl66187 E3_activity/RING/RING 29.1 14.6
MSTLIPPIPHESPTTNINISTTSGVGLGYGIAIAVSILVLISTIMLASYACVRFRSSSGP
RLRNSTVNNDEEAVNPNPTRPAVMIGLPGPVTIKLGRDTQPKNRVPYPEVVLGESKRLPK
PNTGPCSICLSEYKPKQIVRCMPDCNHCFHVSCIDQWLKMSPTCPLCRNSPAPSVGPTPS
GTPLMTEVVPLAFHPR
>Sgl66188 E3_activity/RING/RING 29.1 14.6
MSTLIPPIPHESPTTNINISTTSGVGLGYGIAIAVSILVLISTIMLASYACVRFRSSSGP
RLRNSTVNNDEEAVNPNPTRPAVMIGLPGPVTIKLGRDTQPKNRVPYPEVVLGESKRLPK
PNTGPCSICLSEYKPKQIVRCMPDCNHCFHVSCIDQWLKMSPTCPLCRNSPAPSVGPTPS
GTPLMTEVVPLAFHPR
>Sgl66219 E3_activity/RING/RING 27.1 9.7
MKVPCCSVCHTRYNDEERAPLLLHCGHGFCKECLSRMFSSSLNNSLSCPRCRHVTLVGNS
VSALRKNFALLAVTATGNSSSDDDVSDGDGDVDNDEFEEFEEDRRRSSSASSSGGCSVGG
VIELANHGELKFLQRIGEGKRSGVEMWAATLAGGVRCRGRCRHKVAVRKVAITEEMDVMW
VQTQLEGLRQGAMWCRNVCTFHGVSRGVDNYLCLVMDRCYGSLQSAMLRNEGRLTLEQIL
RYGADIARGVAELHAAGVVCMNLKPSNILLDAAGHAVVSDYGLPSILKKPICRKARAEGD
SSIIHSCMDCTMLSPHYTAPEAWEPVRKSLNLFWEEAIGISAESDAWSFGCTLVEMCTGT
IPWAGLSAEEIYRTVVKARRLPPQYASVVGVGIPRELWKMIGECLQFKPSKRPTFSAMLA
IFLRHLQALPRSPPASPDNDLEACASTNLIEPSPTSVLEVYPYNPNQLHRLVSEGDLNGV
RNFLSKAASGAGSNAVSSLLEAQNNDGQTALHLGCRRGSVELVQAILEYKEADVDILDKD
GDPPLVFALAAGSPECVRALIDRNANVRSRLREGSGPSVAHVCAYHGQPDCMRELLLAGA
DPNAVDDEGESVLHRAVAKKYTDCALIILEHGGSRSMGVRNLKNMTPLHLCVATWNVAVV
RRWVEVASIEEIAVAINILSPVGTALCMAAAAKKDHEKEGRELVRLLLTAGADPTAQDAQ
QRTALHTAAMADDLELMQIILDAGVDVNILNVHNTIPLHVALARGANSCIGLLLSAGADY
NFQDDEGDNAFHIAADAAKMIRENLQWIIHMLKYPDAAVDLRTHRQAKLLNLPSGKTLKD
FLEVLPREWISEDLMEALLDKGVQLSPTIYDVGDWVKFRRSITAPKYGWQGAKQKSVGFV
QSIPDKDHLVISFCTGEARVVVNEVIKVIPLDRGQHVKLKEDVKEPRFGWRGHSRDSVGT
VLCVDDDGILRVGFPGASRGWKADPAEMERVEEYKVGDWVRIRPSLTTAKHGLGAVTPGS
IGVVYCIRPDSSLFLDLSYLPNPWHCEPEEVEHVEPFRIGDRVCVKRSVAEPRYAWGGET
HHSVGRISEVESDGLLIIEIPNRPIPWQADAADMEKVEDFKVRDWVRVKASVSSPKYGWE
DVNKNSIGIINSLEEDGDMGVAFCFRSKLFCCSVTDMEKVAPFEVGQEIHVMQSISAPRL
GWSDESPATVGKIVRIDMDGTLNVPDLKPWLSQANVAVVQTVTMARFRKVYFEFPEQTFL
CRRNFSGAEDVEKGSLVKVTGRSSLWRVSPGDAACLSGFEVGDWVRSKPILGTRPSYDWS
SIGKEGVAVVHSVQENGYLELACCFRKGKWHAHDTDMEKIPNLKVGQYIKFRAGLAEPRW
GWRGANPNSRGIITSVHADGEVRVAFFGLLGLWRGDPADLEVEAVFEVGEWVRLKDGAGN
WKSIGPGSIGVVQGLGYDSDEWDGTVSVGFCGEQEKWTGPISHLVKADKLVLGQKVRVKL
SIKQPRFGWSGHSHGSIGTITTIDADGKLRIYTPAGSKAWMLDPSEIEVVEEEEIYIGDW
VKVKESVTIPTHQWGEVNPSSIGVVHRMEDGQLWVAFCFMERHWLCKASEMEKIRAFRVG
DKVKIREGLVAPRWGWGMETHASKGEVVGVDANGKLRIKFRWREGKPWIGDPADIALDET
>Sgl66250 UBD/UBC-like/UBD_UBC 102.2 0.0
MHKLKFFLLKWISTFVQKPTKRRPTRRRTPLRPPSSSIDDRGKMINLFKVKAKQRENAEN
LNGKAPGKKQTAGELRLHKDISELNLPKSCTISFPNGKDDLMNFEVVIRPDEGYYLGGTF
VFSFHVPSVYPHDPPKVKCKTKVYHPNIDLEGNVCLNILREDWKPVLNVNTVIYGLYHLF
TQPNYEDPLNHDAAAVLRDNPKMFENHVKRAMSGGYVGQTYFSRCIS
>Sgl66254 E3_activity/RING/RING 10.2 7.2
MEEQISSSIPRDHKLCGFLTTVLSSSLNSEFKTLEFGTILEFSSTGSNVVFKSDSGVVLS
PINLPNLKPNSTAKKRSNKKKKEFVYVTPKKRRRKEVDVEVKSLNSNSNAKRLGIGHGNG
TVSVVQQVKILVNQKCLKIVARVVGVSKAEDGEVRVAVLVDVYLPNDVWESGWQFPRSAT
TAASLFRHLRCDWGERTSILNNSHNKDVGDNKVLWNLADCHVIGCKLHSDIADSSEIKGY
ELHEIFKSLPSLNGDLKTYSSRISPKDMTSVSGIWDVTDDIVVNILSKLGPIDLVRVSAT
CRHLRLLSISVMPCVKLKLFPHQQAAVEWMLQRERKVSTLPHPLYLDFYTDDGLAFYLNI
VSGELLTGSAPTFKDFRGGMFCDEPGLGKTVTALSLILKTLGTLADPPEDAEIHWCSHKA
DQKYGYYECSGIRCTDLAVPSLSQRCVSQNDRRGQFSPDDLIPMDQSTPKNTRLQAYCGE
TASSSCPERLDSASSLLSPSTTMATVVRCKRRLNHVKRNLLHQYKSHCSDSVSSDDDWTG
SYSGKRKYTSNNRSNVALNKQKSYRGKRRRKVSEDQYVVSDETWIQCDACKKWRRLLDGS
LADSTADWFCSLNSDAEYQSCNAPEESWDCREPVTYYRGFCSEESPGGLPQNVAFFTSVL
KEHYSLLNFHTKKELTRFARFSQNQLLEMKRVGLAHAGQVATKGAIGFHKIFEAFGFVKR
LEHGVGRWFYPKTLDNLVFDLPALRIALCKPLDSFNMYLSRATLVVVPSNLVDHWKSQIQ
KHVRPEQLRLFVWTDGKKKKPSVHNLAWDYDVVITTFERLSAEWKPPKRSVLMQVHWMRV
MLDEGHTLGSSVTMTNKMQMAVSLSASNRWILTGTPTPNTPSSQVSHIQPMLKFLHDEVY
GKSHKNWEAGILKPLEAQMEEGKSRLLQLLERCMISARKADLRCIPPCIKKTTCIDFTEE
HAKTYNELVVTVRRNILMADWNDSSHIESLLNPKQWKFRYSTILNVRLSCCVAGHIKVSE
VGQEINEAMDILVQNGLDPLSEEHALLRYYLKYGGNCQRCNEWCRLPIVTPCRHVLCLDC
VALDSEKCVFPGCCYMYEMQNPEIRTRPENPNPKWAVPKDLIELQPSYKQDNWNPDWEST
SSSKVAYLVQRLKEIQVASRERVCSMRKYAERPYGIVLSHGTCYLQNVDSSETPVEKVLV
FSQFLEHIHVIEQQLAFADIRFAASYIPMIPKDKKKALANFHEDPSCMVLVMDGSAALGL
DLSFVSHVFLMEPIWDRSMEEQVISRAHRMGAVRPIHVETLVMRGTIEEQMVEFLQNGDA
CRRLLKEDRDKTDHEGARTYKSLHDFAERTYLVRLSMVRTKASSP
>Sgl66258 E3_adaptor/Cullin_RING/SCF/F-box 13.6 0.0
MKILDNLEFMAEKFIQVSSVDPTPYVSFFRFFATKIFSLSNTILELIYSQPKEQHRVLVS
SSSNVLLPLELESIILQRLPAKQLARCRAVSKRWHDEINSPYFIKTHSNQQNSNTGSIII
FFSFANMSLSIDFHHSPINKGVFNNVACHPLFDEWFHPREIVGSSNGLLCYRATEHSKGH
KIIRFVIHNPVTGTYYTMPPLVHKSGRYACLNMVGFGYDCIGNDYKILCTVKCRSIDDAF
RVPTYEYNVYSLKADSWKKIQPRHNVHAICYTVMVLSNNMLHVIVPGDIFGFNLATEEFH
KVTQPNYDNNEYNSVLPTSCALASVGGCLHLTKYIVEPFTNYGVPKLGFEGDTTIWVMNE
YDGSKQSWTKLVRRISAKQLIEKGGLKNSCRISYLPLPLAYSEDGSEILIGAAQSGYIEK
YVRCNVRSGELKKFETYCLAYDHCKTGIGCQVLPWSGSLVELPYKSAELKR
>Sgl66259 E3_adaptor/Cullin_RING/DCX/DWD 18 1.1
MVRRWHETPQIEVLNAHDNAVWDLAWHPVGYILCSGSNDHTTKFWCRNRPGDTGRDKINV
GYNQGYSEQNPAFANRAPGNFPMPEPPTTPGSLPPGLSRNEGTIPGVGAAMPLSMDSSQG
EQMQAHPSSMPMGAPPLPPGPHPSMLTSNQPQGYQHNSQQIPQQGHPQQMPSFPQPPPNM
PQLQPQSHMPMHHHMHRPPPQMPPHNMPSNIPSSMPGSMPMPPASVPMSMPGPMGMQNVT
NQMGQQMQQGHFMGMNPMQSGPPSGGMPPPGGGFSNGMPNMQGPPTTSGPQMYPPAGAFN
RPQGGQMPMMPGLGPYQPSNQSGLPPPPLPPGPPPPQTQQ
>Sgl66263 E3_adaptor/Cullin_RING/DCX/DWD 111.6 18.0
MMYGDPPPPPPPQQQHQQQQQQQQQHMQHQQQQQPLPPPPPPPQLHMHHPPPQFQHQHQH
QHQHQHQQPPPMDFHRGPPPPPPMRPPPSNPNLPPPDFHHPPFESHADNFAAKRMRKLTQ
RRAVDYTSTVVRYTQVRMWQRDARDRTTLQPTPGAAVDLLPPAAYSDNPSTSFAAKFVHT
SLNKNRCSINRVLWTPNGRRLITGSQSGEFTLWNGQSFNFEMILQAHEQAVRSMVWSHNE
NWMVTGDDGGSIKYWQNNMNNVKANKVAHKESIRDLSFCRTDLKFCSCSDDTTVKVWDFA
RCQEEKSLTGHGWDVKSVDWHPTKSLLVSGGKDNLVKLWDTKSGKELCSFHGHKNTVLCV
KWNDNGNWVLTASKDQIIKLYDIRAMKELESFRGHRKDVTALAWHPFHEEYFVSGSFDGS
IFHWLVG
>Sgl66272 E3_adaptor/Cullin_RING/SCF/F-box 13.3 0.0
MASIAEEEHLNPFSKVISMSKMEDNHKWRRLSKCSSTTFDSPINTLDDGCLMHILSFLSP
IPDRYNTALVCHRWHFLACHPRLWLRVDRTIKDSSEPNVFSSVDAAVSAAKAGDTILIAA
GGVHITSNIQIKKPLCLIGGGDLPEETTLICSRGSDSALEFLSTCKITNLTVKAELGCCL
LHRSGRLIIDSCVLQCETDPLDYLSCPIVSTASGPKKLPSSLSPMSLGDGVTVSRTQIEG
GAKAVMTIGTLVLQRVRVIYGRSSVLFWVYQILIFFLFIYHHPLRKFEFQTFIFFHSSNF
ETKDHNQLIHSNSKR
>Sgl66318 E3_adaptor/Cullin_RING/DCX/DWD 85 17.4
MCSILLNPKRSLSTPLLYQSSSATSESGSSTSSSEETGPSFYSSRFNINDVVNAKSILGG
SKSYKLLDILSGHVGPISCLSLCGEFVLSASQGKDIIVWQQPDLKVFTKFGAGEGSVKSV
VTVGNKVFTAHQDSRIRVWKVSRRSENVFRLVDTLPTTKDYLGRFMRQSNYVQVRRHHKK
LWIEHADSISCLAVENGLIYSGSWDKTLKVWRLSDLRCLESVQAHDDAINGLVARKGVVY
SASSDGKIKVWGKDQSVKSSSLNCSSSSLLHKSIGVLEGHKDVSMNAVIVSDEFGMGNER
VYGGASDGYLMGWERKGGGGDGGEWKVVVEVKAHELSILCLNFMGDILCSGSADKSIGLW
KREVLNNGLRGELCKVGVIRGHEGPIKCLQSSLNCVGGGYMLYSGSFDKSIRVWWVSKDI
NDFED
>Sgl66384 E3_adaptor/Cullin_RING/DCX/DWD 71.9 10.3
MAEISASENDSSSSNSTSITDLDVDSLANCANFLSIQDISNMAITCKYFRYAAYSDSIWQ
RLFREKWPENMLGQKPPGSVVREAYLSRRAAVQRFGFVDPLVVDFYTDARPFNHVLLGKN
DIIFSQGSLIQHLKIEDFVKGKECLVSLRDHNARITCMRLFPVKEATFIRCETQNDDNVL
ITSSSDHSIRLWWKGSCLRSFRGHNGPVSALSDKLLGNMGNRVLASGGEDGTVRLWSLSS
SGKRGQHALNATLHGHEKPIKYISAAGHKISLLISVSTDSKIRVWDSSASSRKSSCVGST
SVLGTPVGIKCFDSMLYVAAGYSVQAIDLRTMKTAFTAAVCPPEIYTFDMLASRSLICTG
GKDKALLWDVRKSKPVAEMEGHNGSVTQVHVDPYKIVTGSPEDFFTKVWDVETGVFINSL
NCCPSELSSSRMGCNAMAVDGCRVVTACCGDNGLLRFRDFNNASCSISSYQDAVSSGFWN
SSSYSDSDSDV
>Sgl66473 E3_adaptor/Cullin_RING/BCR/BTB 20.4 0.0
MACIRIGSKSDSLRREGQAWFCESGLASDVTIEIGESSFQLHKFPLISRSGLLEKRIGEI
SSEDGSICIVKLDDVPGGSNAFELVAKFCYGIKLEINSSNVVSLRCAAEYLQMTEDYGEG
NLIAQTEAFFSEIFSSWTDSKEALESCEDVLQQAEDVHVVTRCINSLAMKACSDPSLFGW
PVCGQSKSSKDNKSLWNGISSGDKAEINASATANTADDWWYEDVSSLTFSLYKRLIKAVE
VRGMQPERVSGSIMVYARKNITLLNNQPTSQAQKDAVVPESEDLTTLYEDAQRNLLEEII
NLLPPQKGVTPTKFLLRLLKTSMNLHCNPDCLEILEKRIGAQLDQAALVDLLIPNTGYAS
ETLYDIDCVQRIVDYFMQMQSGVGVSGTSSPAIGEDSGQLGNPTQSIASMTLVAELVDSY
LAEVAPDVNVKPPKFQSLAAVIPDYARPKYDGFYHAVDIYLKAHPWLTESEREQICRLMN
CQKLSVEASTHAAQNERLPLRMVVQVLFFEQLRLRTQISGWFFLSDNLDNSQAREQDEIV
DQDRALVVTGDVRTRVSELEKEYQSMKQEIQKLTKTKKRWSIFARIFARPKPRGPPGQLM
QPKSGHSKVQQSAALLRKHQLENAKHAELDHTKNQN
>Sgl66483 E3_activity/RING/U-box 74.8 0.1
MATQKPQRSPEEVEDIILRKIFLVSLIDPMELNSNSSAVYLELTAAEIMSEGKELRLCRD
VMERVLIDRLSNEFPNAEPPFPYLLGCYRRACEENKKILNMKDKNLRSEMELVIKQAKKL
AVSYSRIHLGNPDMFPGVDDANVNANSMGKKPSPLLPLIYSEAGGALIDSYGGGSSGGGI
TCPPGLLDEFFKEGDFDSLDPIFKTLYDNLREKVVRESALGDFQQPLRALLYLLSIPAGA
KSLVTHKWWMPPGSFLNGRAMEVASILGPFFHISALPDTALFKSQPDVGQQCFSESSSRR
PADLLSSFTTIKTVMNNLYDGLHEALLCLLKKSETRENVLEFLAAVINSNSSRSHLQIDP
LTCASSGMFVNLSAVMLMLCEPFLDANLTKRDKIDPSYVFYSKRLDLSGLTALHASSEEV
SSYISELKNGRADGSTDNSAKNNRLLTSFEATGSGSNSGGPPVQSVTPVSNSGDKVKYNF
ICECFFMTARVLNLGLLKAFSDFKHLVQDISRSEDSLASLKAMHEQTPTRQLELDIARLE
KEIESYSQEKLCYEAQIIRDGGLIQRALSFCRLMVVWLVGLVGGFKLPLPAPCPMEFACM
PEHFVEDAMELLIFSSRIPKALDGVLLDDFMNFIIMFMASPEYIRNPYLRSKMVEVLNCW
MPRRSGSSATASLFEGNQLSLQYLVRNLLKLYVDIEFTGSHTQFYDKFNIRHYIAELLEY
LWQVPSHRNVWRQIAKEEEKGVYLNFLNFLINDSIYLLDESLNKILELKTLEAEMSNTAE
WERRPAQERQERTRQFQSQENIIRIDMKLANEDVSLLAFTSEQITSPFLLPEMVERVASM
LNYFLLQLVGPQRKSLSLKDPEKYEFRPKHLLKQIVNIYVHLARGDEGNVFPAAISRDGR
SYNEQLFSAAADVLIRIGEDGRIIQEFVELGAKAKFAAVEAMDAENALGDIPDEFLDPIQ
YTLMKDPVILPSSRVTLDRPVILRHLLSDSTDPFNRSPLSPDMLIPDHELKAKIDEFIRS
QATGNQGDGIPLQSTKVTLPNPTTDVQLID
>Sgl66543 E3_adaptor/Cullin_RING/DCX/DWD 24.7 0.0
MYLYSLTLQKPTGIICAINGNFSGGKVQEIIVARGKVLDLLRPDDSGKIQTLLSVDIFGA
IRSLAQFRLTGSHKDYIVVGSDSGRIVILEYNKEKNVFDKVHQETFGKSGCRRIVPGQYL
GIDPKGRAVMIGACEKQKLVYVLNRDTAARLTISSPLEAHKSHTITYSICGVDCGFDNPI
FAAIEMDYSEADQDSTGQAAAEAQKHLTFYELDLGLNHVSRKWSEPVDNGANMLVTVPGG
GDGPSGVLVCAENFVIYKNQGHPDVRALIPRRADLPAERGVLIVSAATHKQKSMFFFLLQ
TEYGDIFKVTLDHGNEGVSELKLKYFDTIPVSSSMCVLKSGFLFAASEFGNHALYQFQAI
GDDPDVESSSAQMMELETDEGFQPVFFQPRRLKNLLRVDQVQSLMPIMDMKVINLFEEET
PQIFSLCGQGPRSSLRILRPGLGITEMATSPLPGVPNAVWTVKKNVNDEFDAYIVVSFAS
VTLVLSIGETVEEVSDSGFLDTTPSLAVSLVGDDSLMQVHPSGIRHIREDGRINEWRTPG
KRTIVKVGYNRLQVVIALSGGELIYFEVDMTGQLMEVEKHEMPGDVACLDIAPVPEGRQR
SRFLAVGSYDNTIRILSLDPDDCMQVLSLQSVFSPPESLLFLEIQASTGGEDGADHPASL
FLNAGLQNGVLFRTVVDMVTGQLSDSRSRFLGLRAPKLFSIIVRGRRAMLCLSSRPWLGY
IYQGHFLLTPLTCGTLEFAASFSSDQCAEGVVAVAAEALKVFTVERLGETFNETAIPLRY
TPRKFVLQPKKKLLVMIESDQRAFTAEEREAAQKECFGAAVDENGNIEMENGDEDEDNQL
SDEQYGYPKAEKEKWVSCIRVLDPRTEETTCCLELQDNEAAFSICTVNFHDKEYGTLLAV
GTAKSLQFFPRRSYDAAYIHIYRFVEGGKLELLHKTQVDGVPLALAQFQGRLLAGIGPVL
RLYDLGKKRLLRKCENKLFPNTILTIHTYRDRIYVGDIQESFHYCKYRRDENQLYIFSDD
VYPRWLTAAHHVDFDTMAGADKFGNVYFVRLPQDVSDEIEEDPTGGKIKWEQGRLNGAPN
KVEEIVQFHVGDVVSSLQKASLIPGGGECIIYGTVMGSLGAFLPFTSRDDVDFFSHLEMH
LRQEHPPLCGRDHMAYRSAYFPVKDVIDGDLCEQFPTLPMDMQRKIADELDRTPAEILKK
LEEIRNKII
>Sgl66572 UBD/Alpha-Helix/UBA 19.7 0.8
MNLRLRLLLSKQSLTNFRRFTTSSSSAIVAPYNKQNRFHNHSKSPLPKTPSFQNTQKTNF
HSSHQLNQSQSTAMIVADDDEEDEDVAALNEFLSRFVHIMRGNLNETYPQCDKPTIDAML
KVIVEKLVSEMEKGGNLEERLVSNGGDGDFSDDLWKTVLEVSNNVYQEMEREKKKEKLKM
FLQCDEVKGLARFASEVGVRGDMLHELRFKWAREAMEKAEFYEKLESIGEAAVAKAEAEA
EAEAEKESNAGGDDSGGLPKRHGKIKYKLYGLDLSGSQWKEVADRIHDAGEVIWEKEAKA
ITGKCKLVNEKIIGLSESQFDSEISPLLDEWKELLQPNKVDWMLLLEKCKEKDSSLYLKM
AERVLDEPSFQATTTDYSMLVEVHAKADRLEDVDRILKKMSDRGVPRDILTLKALLHMYS
KTKNLEQAKAVYEELNSQGFKLDMELYKSMIMVYVNAGNPKLGEKLMREMDVRDIKPTEE
IFMALMRAFAKRGDIIGAQRVVTTMQFAGFPQTAESCACLIEACAKSNYPDDARRYFREM
MNLGFKPDDKCTSLMISAYEKNNKLEVALHLLLELEKGGFEPGVLTYSVLIDWLGKLKLV
DEAEQMLAKMAQLGEVPPFKLQLSLCEMYAGAGNEKKTLQALGVLEAKKDLLDHQDFERI
IMALLNSGLVQGAQRMQTMMEAQGFTPSEGLKIKLMSIQAFSGNTGIGSTRPRMR
>Sgl66622 E3_adaptor/Cullin_RING/DCX/DWD 110.8 6.6
MNKMSLINEFQVEFTQRSSRVKSLDLHPVQPWVLVSLYSGTIQIWNYNSKNMEKSFEVSS
NVPVRSAKFVAQKDWIITGSDDKMIRVYNYKSEEKLKEFVAHEDFIRHIVVHPTLPCVLS
ASDDHHIKVWDWENDWTCTRVFEGHSHYVMQLAINPLDHNNFASVSLDGSIKIWNLENSN
PSASLADAHAKGLNCVKYYVTTEDKLYLLTGSDDFTTKVWNYESLSCLKVLEGHTGNVTA
IAVHPNLPLIITGSEDRTIHIWNAIDFNLENTLDHGLGRVWVMEIEKNSNQVFIGYDEGH
LMGNIGTHSAKLKRN
>Sgl66704 E3_adaptor/Cullin_RING/DCX/DWD 24.8 0.0
MYLYSLTLQKPTGIICAINGNFSGGKVQEIIVARGKVLDLLRPDDSGKIQTLLSVDIFGA
IRSLAQFRLTGSHKDYIVVGSDSGRIVILEYNKEKNVFDKVHQETFGKSGCRRIVPGQYL
GIDPKGRAVMIGACEKQKLVYVLNRDTAARLTISSPLEAHKSHTITYSICGVDCGFDNPI
FAAIEMDYSEADQDSTGQAAAEAQKHLTFYELDLGLNHVSRKWSEPVDNGANMLVTVPGG
GDGPSGVLVCAENFVIYKNQGHRDVRALIPRRVDLPAERGVLIVSAATHKQKSMFFFLLQ
TEYGDIFKVTLDHGNDGVSELKLKYFDTIPVSSSMCVLKSGFLFAASEFGNHALYQFQAI
GDDPDVESSSAQMMELETDEGFQPVFFQPRRLKNLLRVDQVQSLMPIMDMKVINLFEEET
PQIFSLCGQGPRSSLRILRPGLGITEMATSPLPGVPNAVWTVKKNVNDEFDAYIVVSFAS
VTLVLSIGETVEEVSDSGFLDTTPSLAVSLVGDDSLMQVHPSGIRHIREDGRINEWRTPG
KRTIVKVGYNRLQVVIALSGGELIYFEVDMTGQLMEVEKHEMPGDVACLDIAPVPEGRQR
SRFLAVGSYDNTIRILSLDPDDCMQVLSLQSVFSPPESLLFLEIQASTGGEDGADHPASL
FLNAGLQNGVLFRTVVDMVTGQLSDSRSRFLGLRAPKLFSIIVRGRRAMLCLSSRPWLGY
IYQGHFLLTPLTCGTLEFAASFSSDQCAEGVVAVAAEALKVFTVERLGETFNETAIPLRY
TPRKFVLQPKKKLLVMIESDQRAFTAEEREAAQKECFGAAVDENGNIEMENGDEDEDNQL
SDEQYGYPKAEKEKWVSCIRVLDPRTEETTCCLELQDNEAAFSICTVNFHDKEYGTLLAV
GTAKSLQFFPRRSYDAAYIHIYRFVEGGKLELLHKTQVDGVPLALAQFQGRLLAGIGPVL
RLYDLGKKRLLRKCENKLFPNTILTIHTYRDRIYVGDIQESFHYCKYRRDENQLYIFSDD
VYPRWLTAAHHVDFDTMAGADKFGNVYFVRLPQDVSDEIEEDPTGGKIKWEQGRLNGAPN
KVEEIVQFHVGDVVSSLQKASLIPGGGECIIYGTVMGSLGAFLPFTSRDDVDFFSHLEMH
LRQEHPPLCGRDHMAYRSAYFPVKDVIDGDLCEQFPTLPMDMQRKIADELDRTPAEILKK
LEEIRNKII
>Sgl66797 E3_adaptor/Cullin_RING/DCX/DWD 96.6 6.9
MDYKLSPSDKKNTLSKFFKEEEKQSSPSFHHLSLVQHLQDNLSSAYGTHLLSEPGSPLLP
QSPESLWSHSPLQSPSHPSLLYCCISSLHREGDIYSIAVSGDHLVLTGSSSRRVHAWQAE
DCHAKGYIQASTGQVRAMVAHGEILFTSHKDHKIRIWNIRNCNGSNNNFSPKKITTLPSS
NNHYFKNFISRPLIAPPLKPIITPLHKDTISCMAYYHIEGILYTGSFDKSVKVWRINEKG
CVDSFIAHAGNVNDMVVNQQNGYLFTCSSDGTVKMWLRVYGENTHALIKVFTFHTYPVYA
LALSVSMSQESVLYAGSSDGCINFWEQQLSCRYTHGGILQGHRFAVLCLVTLEKLLISGS
EDSTIRIWRREKGKHECLAVLEGHRGPVRCLNAVLQKDSFAVSFLVYSASLDQTFKVWRV
KLLPSEIKNDYSNKKSSLKDDDDHVIDTTTTTIDHHHTSPVLSPSWVKKKLQCRNLKK
>Sgl66799 E3_adaptor/Cullin_RING/DCX/DWD 94.9 15.7
MDPELTHNKTLCNFFDEEITEDHSPSFQHLSKHSPSQILPQSPESLWSCSPSLTPPHPSL
LYCCISSLRRDGDIYSVTVSGDLVLTGSNSRRVYAWQSNDCHAKGYIQASSGEVRAMLSY
DDMLFTSHKDHKIRIWNMRSFGGNFRARKIITLPSASHFKNFIYRSIAPTHHKLTSKLIT
PQHKDIISCMAYYHVEGILYTGSFDRTVKTWKLRDRKCVDSFIAHGDHINGMVVNQQSGY
LFTCSSDGTVKMWVRVYGECSHVLVKVFSFHTYPIYALALGTSPSQRSFLYSGSSDGCIN
FWVQEISTHYNHGGVLEGHQFAVLCLVTVENLVISGSEDSTIRIWRRERGRIIHDCLAVL
EGHRGPVRCLAATLQDVHATSFLVYSASLDQTFKVWRVKLLREIKKSTGHRLSCGDDDID
DGPSAPSPVLSPSWVKKKLQCRSLK
>Sgl66811 E3_activity/RING/RING 23.8 12.7
MEPTYPIAPPPPPDHHHQRHESTTRLQPTQAFADRILRAIGHRLLLLYRSDPNFYVLGAT
GNVYVVNVSTTLACSCPDRATPCKHILFVLIKVLGVPLDEPCLRKRTLRPSHLAQLLANP
SLPDSFASPTLCQRFYQAYFLQRDQGEAAQSSSATVVEDGVMCPICLDEMGKSGKKLVAC
GTCRNCIHEECLMAWKRTQRRRTFSCVICRSRWKDMVEQERYLNLAAYVNEDDHMGPQPA
GSTTCHE
>Sgl66884 E3_adaptor/Cullin_RING/DCX/DWD 94.1 18.4
MKALNEELVFLILQFCREEQLNETVHVLERETSVFFDLNYFETLILSGNWDKVERYISGY
GSLKDDKLLSKVHFEVMKQKLLEALDIGNHAKALEIVRNEPNVFASYEEELVKEIAQLKS
FDDFREHKLLRNYGDIHSARSSLFKELRKIIQGHPGFQKKLEFPTIEIARLRHLINQSLN
WQHLRCQSPEAIPEIETLYEDHMCQPNDQFIESIIEPAYPVYPETTAVSSATDSDGCETE
LSTDSQEEVRPYHSPESEFIDLPVTIGCVLNEESSPTTMDFHPSDNSILLVGTDDGGVSL
WDIALRRRLLSRNFKVWYVGECTSKFKEAFTNNPHVSAKCTRWSSRGDLIGVAFSKQIVQ
IYTYEADNGMLESLEIDAHDGSVNDISFSKPNDETFAITCGDDKMVKVWNASTGAKRYVF
DGHKAAVICACPTVIKGVNLIFSTSETGEMRGWMYDNLKYRVAVDDPCRRRMVCSKDGKR
IFSCGINEEAQSCILEWDTESNNVKQTYQGLKKPCPGVVHFDTAKNQILAAGDDHQIKFW
DMRNLELISSTDTGESLPVYPYIRFNKDGSLLAVSASDNKIMIMATAYGLEFLTSCQEHH
SVVCVRDDDNLLEVACNSISEDNNSHEPLLLDTDPGLHIRWLSSDVKDGKICRMAYSHSG
NSILALTWDGTLLVWRWSGSDTNSMDIDGAVGTMPQLWKPENSSSVMLNIHGPQPDLVVP
CFALTKNDAYLISGSGGELSLLDILAFKRLFTFIPPLPQTTAVAIYPKDNNVIAIGGNDS
TILIYDIPFGEIKCKLEGHSRKIIDLAFSTALDILISSGADSKICVWDTERWEMKASMYL
DGLTEARIQFHQDQVHFLVIHDTALAIYEAQKLQCRNQWFIGENCSPISCAAFSCNGNMI
YVGFCDATISIFDASSFQLRSRTRCQFSSVDIHPMAIAVHPKKAYQFALGLSDGTAAIFE
LSEPNCRSTIPPPKESPLMACYDSSESQLPSLNPTLVGPDSSPTDTCKLHIPLNPNFQAL
TPTTCKKMKICYSKKYT
>Sgl66899 E3_activity/RING/PHD 37.7 5.0
MTSFLDEFQANLELLPNILQKKYALLRDLDKSLQDILRQNEQRCEQEIDDIKQAMLSSST
RPDPSRIRFSDEALDEQKHSIRIADEKVALALQAYDLVDTHIQQLDQYLKTSEEENRREK
GLASTSASPDDGSTKNGRGSEGGRGGRKKTRLAAAAAATVPVNPPSMDLDVPVDPNEPTY
CLCNQVSYGEMVACDNPDCRIEWFHFGCVGLKEKPKGKWYCSDCASTHKRRKGK
>Sgl66945 E3_activity/RING/PHD 36.7 5.1
MSSLAERLRVRSERRPVYNIDASDDEADIGPGKSRPPSEKPERIVRDDTKEDSCQSCGES
GDLLECESCTYAYHPKCLLQPLKPPFPADWKCPECVSPLNEVEKILDYEVRPTAAEDGDA
SCWVQSKFLSSNISVPEKEFIKA
>Sgl66956 E3_activity/RING/RING 40.7 9.9
MVEGMGEIVVTVTGYCGTERMKSGANSFGKMSKSVTHLVCWKFEREKYRFAKNYGIRIIN
HQWVDDCIKEGKRVPEFPYTQKSGQKVGFHISNIPAALETAGMLSENWKLLNKPSIHDYL
DEMNLHSVEIRNTDWDNNPLLDEYPTKQRRSNTDRSIEMGSDYAEPSHRNRRLVKKNAEQ
QSKKNEDGIQVNGCTVSTSTSDDIIDLSTEIEPSISRRVENASAAHGESTDEINYVTDLD
PLLDTSLYGDNALNVEGRNVKETSPGEKLNEDKCNKDQSAVGVSVDLSCVICWTEFSPIR
GVLPCGHRFCFSCIQSWSQHMASSRKESRCPLCKETFASITKVDATASSDQKIYS
>Sgl66958 E3_activity/RING/RING 40.2 9.9
MVEGMGEIVVTVTGYCGTERMKLIKLINYSGANYVGKMSKSVTHLVCWKFEGEKYRFAKN
YGIRIVNHQWVDDCVKEGKRVPEFPYTQKGKLLNKPSIHDYLDEMNLHSVEIRNTDWDNN
PLLDENLSPSLSRRETARQRSKKKLVKETSREDRRGKAVTKRANELQCEVSDYLPKYPTK
QRRSNTDRSIEMGSDYAEPSHRNRRLVKKNAEQQSKKNKDGIQVNGCTVSSSTSDDIIDL
STEIEPSISRRVENASAAHGESTDEINYVTDLDPLLDTSLYGDNALNVEGRNVKETSPGE
KLNEDKCNKDQSAVGVSVDLSCVICWTEFSPIRGVLPCGHRFCFSCIQSWSQHMASSRKE
SRCPLCKETFASITKVDATASSDQKIYSQTIPCPSSAQDLFIVPEGRSYLSNFEMAPPSV
CCNCQRGDPVEFLEYCQFCLSSCIHYYCLDPPLFPWTCIHCRERRLPFRN
>Sgl66969 E3_adaptor/Cullin_RING/SCF/F-box 12 0.1
MEEQTAIVNQSSRRHDYIPFELWIEILSKLPLKSLVICKAVSKEWKSIVVFLIKKSDVVP
ICGLFLRVHNTVEGRILRRIIRLILNNDNNNINDNHINMLGYTCLKTRKAINIQKNTRVI
NNSGYDRGILSNLCFDVGALLKYNVLNPSTWLFGGLNPGTFFSFHGGLLLVGFYGGTYEV
HNVATKQVVTVPKSPSNAFKYLLMTVIMGILGIRSHHRQDAIVEVPSDKIGTVSHFIVVR
FRPQFQHTEVYYSKDGKWDVIPMDRYDYILPYEWFTLNYASLFVGKSLYLFFLTSKGHCI
ALRILGTKMNPRKGYCTFRVPRLVHGKYSRTRLWECDKSLHLSYYGVGEIRLWKGNCSVH
NFRSWGWIPQLVITNSLQLSTLHLTKKNAQRYVAKAIDAGHRVMPLTCHPRLPVIFILVK
STIYAYHYLNDCLEEMGQIGDDYENIDHVYPFKPSLNSLPIVVKQDSFFPSSFSLASFVI
HLVERINPRSFILFVTFVCLFIKFVDGTPLSFMIVVLYLFCIVLEWNIASYVVGHFEFSR
VVLILCVLSSVLVWYYYHT
>Sgl66973 E3_adaptor/Cullin_RING/SCF/F-box 14.6 0.0
MIMAPPKVIKTYENTTKRQKTMKRSSKTRLTNKFTVDDDHINDEVLTSPPIMECLPTEII
AEVLVRVAVSSPVDLFRCKLSCKAFQEMSEEKNILQQVSLDNLMSRHSWLTDNAKHFFMK
CLANNNPHALIHFGLVQCFSDMMLEEGLKNLEKATEQGNKDAGYVLSLILLCSGDKECIK
KGTDLMLNIMRVIRGKGIVECRKKLRDFMRSMWIVNKFIAKTKPQFPCALKQQHEIRNNW
YKADYYHEEGEDTVVCESCKIVREINFFCQLFGE
>Sgl66977 ULD/UDP/UBQ/UBQ_PIM 51.8 0.2
MQVVIVTNNFTNFSLEITPQEPVLVIKQKIANILGIPVFFQTLSVLGIELINGLDMDDYP
IINEGTRIDLIVSSTDEEMITPPMDDYYTEHTSSHTKIPVTIKFSTREINIEVDMITETV
RSLKEKIHIIDGTPIKRMLLYTSGVEMEDEFRLLSEYAIHEYSEIAVFLRSMNRLKAEPP
CRKLKMVVQTSKSLLNAASIPLEMKDSCTLNEVRQFMLSRRILPMDDYIFIHKQRIMRDN
CTLRWHGVENGDYLYVFKGTISKNGC
>Sgl67026 ULD/UDP/UBQ/UBQ_Other 24.8 0.1
MGRLSFKVANNDVDDIFGVGRDGLYLSRVSISSKNRRSFCRSSSSISTALSIVNSRKSFS
YDKLAQAPIHLSVVKLDGSRFAIEVIKMATVSDLKQAVESAFSHLPTKGPGKVSWRHVWT
QFCLSYCGQKLLNDNEHIKNYGVKDGDELRFVRHVSIAYNLIKKRSSKRIEAPKPNSVAE
NGEEESNKVEEASADDLENVRNQIEVKTSHNESKVPLSNNGWVQYSRLSSTEQLKFEKQA
NQSRWAGGFIGSLRSLFHFCDKRHPSYSSRVSQVEI
>Sgl67081 E3_adaptor/Cullin_RING/BCR/BTB 68.1 0.1
MMANLDAGEVITATTDPKRTETADISSSKSVIETVNGSHRFEIKGYSLAKGMGAGKYISS
DIFSVGGFDWAIYFYPDGKNPEDSSAYVSVFIALASEGTDVRALFELTLVDQTGSKKHKV
HSHFHRALESGPYTLKYKGSMWGYKRFFRRPALEASEYLKDNCLLLECTVGVVKSRMERP
KQYSINLSPSDMGNCFKDLFENEIGCDIVFQVGDEKFHAHKLVLAARSPVFRAQFYGLIG
NPNMETVVVEDIEPSIFKAMLLYIYSDSLPDVHEIMGANSSCSFAIMVQHLLAAADRFGL
DRLRLLCESKLCEKITIETVTTTLSLAEQHRCEQLKTVCLSFAAENLNAVMKSEGFKYLE
ESCPSLLSELLQTIASVDDTSGLPVSKKRSISSVFACDLAGADGGIQAEAANSNGRRMRR
RL
>Sgl67104 E3_activity/RING/RING 32.3 6.8
MSSTTLTTSTTSPTSYWCYRCNRFVRVSPNPLSIVSSISCPDCHGGFLEEIDSHPSTPPP
PLPSQLSSSSLSDSRRRRFPAAAMYMVGNGNSNNLNTTTNTPSLSSSSPRLRRSRRNGGD
RSPFNPVIVLRAPSESDAAPAATGGGVGSGGSYELYYDDGGGSGLRPLPASVSEFLLGSG
FDRLLDQLAQIEINGIGRAEQPPASKAAIESMPTIEIVDEHVEGECYCAVCKDAFELGSE
AREMPCKHIYHHDCILPWLSLRNSCPVCRHELPADNNTTRADSNSIEPNPGTNSNTNLNS
ISSGNNHSNGGLVESNEDETVGLTIWRLPGGGFAVGRFSGGRRGERELPVVYTEMDGGFN
QGGVPRRISWGSRGGRSAESGGIRRVFRNLFSCFGGNRNQMLEDSTSSSTDSRANNSQRS
RSTSFFSASSRSRSRGFDMGSRIRR
>Sgl67106 E3_activity/RING/RING 30.8 6.0
MSFVFRGTRADIENAFPGMVPDRGVRIHATRPVNSNSLAFLVTVLLLFMILNSNQMSPNF
LLWLVFGFFAMATALRMYATCQQLQAQAQAHAVAASGLLRHTELRLRMPPSIAFASRGRL
QGLRLQLALLDREFDDLDYDTLRALDADNAPAVPSMSEEEINSLPVHKYKFTGADCDIAV
KQHPSSSVSPEKQQDISFNVSSSKSSSEDELTCSVCLEQVNVGELIRSLPCLHQYHASCI
DPWLRQQGTCPVCKYKIGVGWPGDGHEDAAYMV
>Sgl67114 E3_adaptor/Cullin_RING/DCX/DWD 90.4 16.5
MELEQRRKSGLNLPSGMSQTSLRLETYRPTTPKTANETTPLRSNLCLSSPRSVSSPRSIT
SLSSATSSPTSKKSICSDRFIPCRSSSRLHTFGLIEKSSPTTNNKNNNNNNSNSKDGGNH
EAYTRLLKQELFGADFVSSPAGSPMSSPNKNMLRFKMEYSSPNSHFSPSGLGRDSGVSNE
VSTPPKPPRKVPKTPHKVLDAPSLQDDFYLNLVDWSSQNLLAVGLGNCVYLWNASNSKVT
KLCDLGPNDGVCAVQWTKEGSYVSIGTNNGQVQVWDGTQCKRVRTLNGHQTRAGVLAWNS
RTLASGSRDRNILQHDLRVSNDYVSKLVGHKSEVCGLKWSHDDRELASGGNDNQLLVWNQ
HSQQPILKLTEHTAAVKAIAWSPHQSNLLASGGGTADRCIRFWNTTNGNQINSIDTGSQV
CNLAWSKNVNEVVSTHGYSQNQIMVWKYPSLGKVATLTGHSFRVLYLAVSPDGQTIVTGA
GDETLRFWNVFPSVKTPTPVKETGMWSLGRTYIR
>Sgl67166 E3_adaptor/Cullin_RING/SCF/F-box 11.9 0.0
MNDSWVMQGNMPNNSNNPLVFTACSERLSLVSSGADLIAGNEHLLSEILGRLPTKSVVKF
KSVSKNWNSLISSPHFSFLHLIHNSNGPIPISGIFLRRRCVPSPYAYRFLSVCDFDVNLP
SFSAASSSSIEIPGLVVSVLQSCNGLLLYYSIDASNSKALNLHVYNPTIGQLRTIPSIHN
SFVSATLAFKPHSSSNRYKVISVHTTMSFDHYALKIYSSETGCWTDLDGKHIIVPNDMDL
KNAVYWRGSVHWVCRSEGSLYLEVDEERVKRMPSPLIIGSERGHMKCFECKGKLWCLWHE
YNGSILEVNMMNSYEEGWFLKFTVNLGVIRKDGCFFSSYYSDFAILSLTNNRKCHGGEER
MMVIIHVSGKILGYYLEDGATMELCKIALVDGEDADERQFYSFEAYPYSYSLACV
>Sgl67167 E3_adaptor/Cullin_RING/SCF/F-box 14.6 0.0
MATEEDESYNQIIPAMNPHWRKPIEGRLPPDSLIQIWARLPIKSLYKFRSVCKLWNALIS
SDPLLSDLRHRLSHSITFQKPSNLLILLRHLNNEPVKVPDRPIRLSTRPFEEIIRDDRDP
NTHPIRNGFTPYVDFSLNFVPSNGPIVCVAADQYFYLCNPSTQEFLRVSPGQNGNSKTSN
GGFGYLGDVNQYVLVALYGEKCELLEFGPGQARLGLWREVQQRCPCRVTGFGLMVDQGFY
WKVSDGSGFVVCLEVKSEEFKLISPPQGNENEEILYNQLYLVEFKGCLCAVDNFSRPPRM
EIWVLNRFEGEFGWVRKYNIFISGMSRDVVYPFCDYEGENGGEMMLCNDTRSRLYRYNLK
NRSIKQVFRLKNRTGDRLALYSPGLFPLSFAS
>Sgl67169 ULD/UDP/UBQ/UBQ_PIM 76.2 0.3
MQIFVKTLRAKTITLEVKTSDSINNVKAKIILKLGTPSDQQRLIFGGKQLEDGRTLADYN
ILKESTLHLVLRLRGGGYGKMNYPPTLLELARKYMQYKKVCRKCYARLPLRATNCRKKKC
GHTTELRTKKMFQPPKDGGGKEKNKK
>Sgl67183 ULD/UDP/UBQ/UBQ_Other 29.3 0.1
MAAAALRRPLGGDYLSNKKEGNQAVRRRVFVQTETGCVLGIELDGSENVHTVKKKLQLSL
HVPTEETSLTCGDTVLKNDLSIVRNRSPLLLTRNCLHRSSSTPCLSPSTKDLHQKDQSYP
IEVIGCSSHFPVTKQLVNSIVNAMESGIDPVPVRGGLGGAYFFRDINGENVAIIKPTDEE
PFAPNNPKGFVGKALGQPGLKRSVRVGETGFREVAAYLLDYDGFANVPFTALVKVTHRIF
NINHDGVSGNTGHQQREQISKIASFQQFIPHDCDASDHGTSNFPVSAVHRIGILDIRILN
IDRHAGNLLVRKLDDDGVGKFNQVDLVPIDHGFCLPESLEDPYFEWVHWPQASIPFSEDE
LQYIANLDPFHDSEMLRVELPMIHEACLRVLVLCTIFLKEAASFGLCLAQIGDMMSREFR
GQAEEPSKLELICINARSLQKSQMMINSSLEENEDEFQFDLECEVSNGDLSRILEDAVPI
QKNSLEKNGNIGTNYLCKLKETGETKSKTRINGISPGNGSASEQLPISSSFVTLADMNEE
EWTAFLENFQKLLHPAFEKYKSGKVGQRLTQRLGTSCKF
>Sgl67191 E3_activity/RING/RING 35.2 12.2
MGAICSCLRVEDIEDYVNRNSSFYRNCICVNCFLQNFFHMYSSLFRRGEVQSLPSSIQGA
SLTSVVSTDNSLADMYRSPPRPLPYDADPRCYRMQRDGLFSRREKGSSHSHDETEPLRRS
DIDSDSDPLSPGDKWNESTCGDDSKEGRKSSAKLSSAKSTTVMGYFYSSSEDEDVCPTCL
EEYTEENPKIVTNCSHHFHLGCIYEWMERSESCPVCGKVMAFDESP
>Sgl67363 E3_adaptor/Cullin_RING/BCR/BTB 41.3 0.0
MDQGFANVIKWVKEMKDMEEEVNDKLRFIGEFEVAFRDEIHTDILVKPGNNGPPIPAHRA
LLAAKSEIFKNMLDSDDCKEAPNEAITLPELNHEELESLLTFLYRGSLPNDVVEKHVYSL
SIAADKYDISFLQKFCERQMLTSLSSSNALDVLEISDVCSNLKLKDTSLSFIVKNMEDIV
FSPKFEAFALKNPHLSVQITRASWMDIKNRRNAL
>Sgl67435 E3_activity/RING/U-box 102 0.1
MNSPFEVFELRLPTLSGFLPTELLSASLITASDEISSITNIPRLQTKNILAMTRRVRLLS
PLFAEVQELHVPLLPSATLCFTELLSLMTRAKLLIQRCTEGSYLWNLVQTEVLSKEFHAI
IKDMSKALEILPLKLMDITIDVREQVELLRKQAKRADLLVDPKELERRKLVFQIIATTKD
SNNKIYGFLDVGRVKEIMISIGLRVSVDFAEEVSKLKAEAAIQGGTGGPIVVSQIYSLIH
LLTHVRSMIFSFEENEMAFELLKQKNAASKLAPSTSQVIPTDIPNEFRCPITDEIMREPV
VVATGHSYDRDSISKWIVSGRKTCPKSGLKLPHMALIPNYNLKSLIHQWHHDNNIKLDEF
TASSSKQHNTNTTRILGINAVKLTSEFLVGKLATASPEMQCRAAYETRLLAKRSMDNRKT
IAEAGAIPFLVNLLNSNKPAMQENAITALLNLSINSDNKFLIVEAAALEKIIAVLENGET
MEAKENAAATIASLLIVDDYKASIGAQPRVIAGLVHLLREGDTKGKRDAAIALTNLALYN
PNQRRVVHEGAVPLLIDILMDDKAGITDDALALLALLSECSEAMEEITKTTINDLMILLI
DLLRFGSLKGKENSITLLLALTKDSTEVVKHLDPQSFSLLRNLIANGSSKTREKAGLLLR
ILIKCCSNPANL
>Sgl67437 E3_adaptor/Cullin_RING/DCX/DWD 30 1.1
MPRTTTIEAPGCPPLRALTFDNIGLIKVIEARSKQNGVPKVVDRWGDPDSSKAVLAASIN
SSDNPLLAVARKNGAIEVLSPSTGESCFSISDDGDGTSPIDDPIVGLHLFKKQTIKSSPR
SCTLLTCTTKGKASLRRVEYFVSDADSASCATPETWNVCGSGEIHCSKVHVDEGYSVFGG
KGVELNMWDLENTTKIWSAKSPAKNSLGIFVPTWFTSLTFLSKDDHRKVVAGTSNHQVRL
YDISAQRRPVLSIDFREMPIKAVAEDLDGNTVYVGNGAGDLASYDIRTGKLLGCFLGKCS
GSIRSISRHPEHSVIASCGLDSYVRFWDTNSRQLLSSVFLKQHLTNVVFDSNFSDEETVT
IPTDAVPVIEEQSLNEEPSLNEDEVVPVKRKKSSKVKGEGKKKKSKKAKKVKGEVHDDE
>Sgl67457 E3_adaptor/Cullin_RING/DCX/DWD 23.1 19.1
MAMLAKLFNKQSSDSKDTKALIDLNPQVIAHYGIPSTSSRLAYDSIQQLLAVGTLDGRIK
VIGSDNIEGLLSSPKDIPFKNLEFLQNQGFLIGVLNDNDIQVWDLENRTISSVLQWDSNI
TAFSVIQETTYMYVGDDCGLVSVLKYDIDERQILRQQYSIPIHSVFEAAEIPLHNNQSVV
GVLPQPCSCGYRVLLAYDNGVIVLWDITKDQMLCVRGWNYHQMNETDAGGSTSSRSNEEK
DQMLGDDQRDKDIISLCWASSDGSILAVGYVDGDIMLWNMSDTVSGKDYKAGNPANKPVK
LQLSSAQKRFPVIVLHWSASGALDDHGGQLFVYGGDEIGSSEVLTILNLEWSPKKDALKS
VVRTNVTLQGAFADIILLQSCSVLEDTGSTSLLLLTSPGELHYYDSPCLSGYNISDQDKS
SAIPFPYRSVVPTSEPYMTVGKFVSVLENTKCKSALSKFASTMELQETYTSSDKISKWPL
NGGVPCHLSLQGERKVERLYIAGYQDGSVRVWDATYPILSPIFVLNPEVLSITNAGTEGS
VSALDFSSETLNIAIGNSSGTVHLHSLIKDCNENRPQVVPKMQSENEVCESNQGSGSNSS
IVFTLSTSPIITLRYTNFGTRVAVGYKSGQVAMLNISSSSVLFFIDTLSGPGSHVVSFSP
AISLEFYGLSTSLDKSEPHGKSESRKELICSITNDLHIAVLDNSTGDVIGSVSKLHHKES
IAISMYILVGAKCITEVSGGEGGEDIQFLLEEEKEEAEALQVSQAEIDYLDGVNQSTDSV
QSSMDLQILICCTEVLLLYSLKSVMQGQVDSICEVPLLKTSCWTSVFKKNKEEYGLLIFY
QTGFIEIRSLPNLEVWGELSLLSILRWNFRINMDKSMSCTEKGQITLVNGCEFVILSLLA
SENDFRIPQSLPCLYDEALTAALDLNFSANQRTSKESSSGILGEIMRGLRTSKEAQSTNT
VDSPKSLRSVFNKVFSSSKPAASAAAKDAGKVEELSIDGPLRVSPIAPKSEDENKDKSTE
RKKLFDGGTSETKPRQRTIEEIKAKYKKAGDTPSATASAASAASEAKNKLLERQEKLERI
GENSEELRNNAENFSSMAKELAKKMENRKWWQL
>Sgl67470 E3_adaptor/Cullin_RING/SCF/F-box 21.2 0.0
MNVPKLLSSCNELPEEVLIEILLRLPVKSLIRFTSVCKYWFSLIKSPPFAIKHFDTRINL
LPQNDSHFFLTFSSHGDPIAKFLSYETLEISSIFECKPFDDYWDSVYRVSWSFSGPCNGV
FCIEVRKLRSVLLLWNPATREVFVPNQPNQILNFVGFGFDCKTNDYKIVMFDYSGSVQLY
SLRSDSWRGIEAGFSLGEDKDIIEGNHEKVSI
>Sgl67524 E3_adaptor/Cullin_RING/SCF/F-box 12.7 0.0
MSNNRRTMSDEILECILPYIEDPRDRSSISSVCRRWYELDRLTRKHVTIALCYATTPQRL
HDRFPNIESLRLKGKPRAAMFNLIPDDWGGYVRPWIEILESFRRLNKLHFRRMIITDSDL
QFISTVKGHSLQSLKLDKCSGFSTDGLFYIARSCKRLRTLFLEDSNVDEKNGDWFHELAQ
HNTVLETLNFYMTFLEQIKVDDLEMLARNCPLVSVKIGDTDLVHLGNFFRTATRLQEFSG
GSFNEDLDQYANVVFPTQLTSLGPMYLVESHLPVLYPVAHLLQRLDLVYALLNCEGHCDL
IRRCQNLEVLETTNVIGDQGLEVVSLMCKKLKRLRIERGADEQGLGVETGVVTQRGLIAV
AKACPDIEYLAVYVTDITNEALEYVGAHLKKLTDFRLVLLDINETITDLPLDNGVRALLQ
GCQNMQRFALYLRQGGLTDMGLSYIGEFSRKVRWMLLGFAGETDEGLLELSKGCPSLEKL
EMRACCFTEHALATAATRLTSLRYMWVQGYRASQTGIVGILQMARPYWNIELIPGDQYDY
NGNDGQPVRVDHPSHIVAYYSLAGQRTDHPQSVYPLALPDL
>Sgl67544 E3_adaptor/Cullin_RING/DCX/DWD 79.7 3.7
MYTSLKKNDGDWFSGSLSRELGLTQPRNFARRLSASQGLVQQIDLYVKLIGHEGCVNTVE
FNSTGEKLVSGSDDRQVIFWDWALKRKSFAYSSGHLENIFQTKLMPFSDDRVIVTSAADG
QVRVGQVLENGSVETKRLGKHRGAVFKLAVEPGSPYIFYSCGEDGFVQHFDLRSNSSTKL
FSCCSFTEGGRFDYSNSVRLNAIVTDPRNPNFLAVAGSDEFVRVYDMRKCRWDASSDSDK
PVNTFCPPHLKESGNVHITGLAYSNASELLVSYNDELIYLFQKNMGMGTNPRSISTDEEQ
QKLEEPQAFSGHRNSQTVKGVNFFGPNDEYVVSGSDCGHIFIWNKKDSKLVRLMVGDRHV
VNQLEQHPSLPVLATCGIEKSAKIWSPVSRKVQPLPTDVDEIMESNRQGREDHSRVTLTP
DVIMHVLRLQRRQTLAFVERRPRRGNGESEDDDSEGEAYILRFSDRDPTTDEDPRECTIS
>Sgl67573 E3_adaptor/Cullin_RING/SCF/F-box 22.4 0.0
MVEIGEESESRVSRSSSFREIDDSLKQVAALGVGGSRNPSPVGRCCSRNTSPVGRAGSRN
TSPCKQKVVKTKPRGLDEETMATFSKVVQPDVQMEDNIWAMLPEDLLNEILARVPPFMIF
RLRSVCKRWNSILQDSSFLKFHSQVPSHGPCLLTFWKNSQIPQCSVFSLPLKTWYRIPFM
YLPQWAFWLVGSSCGLVCFSGFDGLTFKTLVCNPLTQAWRTLPSMHHNQQRQLIMVVDRK
DRSFKVIATCDIYGDKSLPTEVYDSKVNSWSVHQIMPAVNLCSSKMAFCDSRLYLETLSP
LGLMMYRLDTGSWEHIPAKFPRSLLDGYLVAGTQKRLFLVGRIGLYSTLQSMRIWELDHS
KIQWVEISRMPPKYFRALLRLSAERFECFGQDNLICFTSWNQGKGLLYDVDKKVWSWIAG
CALQSYNSQVCFYEPRFDASIY
>Sgl67577 E3_adaptor/Cullin_RING/SCF/F-box 19.4 0.0
MKRRKSRWSKLPAEIVRSIAKNLEDEGDLRNLRRTCKNWRQSTATSTILPLTINSNPRKK
LYFSTVSLLRPQNHHLGGDVPSTSFSPWMVSKVESTKGNI
>Sgl67581 E3_activity/RING/RING 32.8 5.5
MAEVDPPEQLHQPQLFNSLSSVFLTGPENPSHPSVISVSDCEPVLEPKPIFEPDEDHLLN
YHHHHHRYDHRNDQVSLFTSLIQRSASQNAVISGSTLGLGLGLGSGDSNCRNLGEGESNG
VDLELGLGFGNSNINNNTVVSSNLCQYNEDNRRCFGGLRVINIDDDSDSDSEDEVNGIIV
IDEDDHRNLGFGGVSDFDRPPYCWDYLGFNNGDRSENEEIRETVSDAGSVVNDDFDGFFV
EEGIIEIDDDEDEGTPIQLDTDVSNVFDTYQMRAEQQEIAIDSETDDGGEFGVDEAIRDL
EWEILLAVNNFNREVYDMDFNVDMYEAILGEVEDRMNDWRGSPPTAESVIENLPSVIWSR
EGSEENEVVCAICKDEISEEEVVKQLPCLHYYHGDCIIPWLKMRNTCPVCRHELRTDDAE
YEYRKREREREEGFNVVADEDLSQDSQVRPDFHVFL
>Sgl67593 E3_adaptor/Cullin_RING/DCX/DWD 83.6 15.1
MACIKSVTRSASVAMSPDSEYFAAGTMAGAVDLSFSTSAHLEIFKLDFTSDDHEIPLVAQ
SPSSERFNRLSWAKNGSNSEEFAMGLIAGGLIDGNIGIWNPLPLIRSESTDNAVIEQLTH
HKGPVRGLEFNALSPNLLASGADEGEICIWDLASPTTPKRFPPLQGSSSATQGDISYLAW
NNKVHQILASTSHNGLTVVWDLRKQKSVISFYPDSQRRRCSVLQWHPDVATQLVVASDDD
NSPSLKLWDMRNTMSPVKEFVGHTRGVISMAWCPSDSSYLLTCAKDNRTICWDVVSGEIV
CELPAGTNWNFDVHWYPKIPGIISASSFDGKIGLYNIEACNRYGVAETDFNAAPLRAPKW
YKRPVGVSFGFGGKLVSFHSKAAPAGGSGGASEVYVHSVVTEDNLVSRSSEFESAIQNGE
KSSLRALCERKSQESKSDDDKETWDFLKVMFEDDGTARSKLLEHLGFSVPEEVSEPVQDD
VTQQVSALGLEDNAAEMAGSVDNKEAASFAFDNGEDFFNNLPSPKAETPVSSASNNFVGE
AIPSEEQKQTEPEGLEESPDPSFDNAVQHALVVGNYKEAVALCISADKMADALVIAHAGG
ASLWESTRDQYLKTSRLPYLKAVSAIVNRDLMSLVNTRPLKTWKETLALLCTFAPKEDWT
LLCDALAAKLLAAGYTLAATLCYICAGNIDKTVEIWSRCLSAEPEGKPYVDRLQDLMEKT
IVFALATGQKQFSSFLCRLVEKYAEILASQGQLSTAMEFLKFLGEDISPELVILRDRIAV
SSQPEKEAEKAMTYENSQVLSGSVYGADHADNSQSYYQGTATGLVQSGSGPSHYGGNYPQ
HVPYDRNYAAPTPYQSTPQAPQPQMFVPLQSQQVLQPNFPPPPVSAQPAVTPFQPAPAPI
LKNAEQYQQYQQPQTLGSQLYPGSTTPSYQSGPSGPGPVGSMPPQTGGIPGQRMPQVMAP
APAPRGFMPVNSPGGVPQRPGMVMTQPSSPTQSAPAQASAAPPAPPPTVQTVDTSNVPAH
QKPVIATLTRLFNETSEALGGARANVAKKREIEDNSKKFGALFAKLNTGDISRNAADKLV
QLCQALDNGDYGTAMQIQVQLTTSEWDECSFWLGNLKRMIRTRQNVR
>Sgl67607 E3_activity/RING/RING 30.2 6.6
MNENRPMEMYYTNNGYPYQTSENYMGFFDGFSHPPLNYGYPPVPMPNHQETAYWSMNMNY
RSDYSNAGSTSYYGYEVNNPLPRTEINRRTWEYSPAMHIEEPTMVVQSEENVVTTSDGAD
AEDCPVDDQEADSPEAAWQDDIDPDSMSYEELLDLGEAVGTQSRGLPQELIKLLPTSRYK
AGGFFSRKKSRDRCVICLVTYKIGDQQMTLPCKHVYHSKCGRKWLSINKTCPVCNSEVFG
EELGN
>Sgl67636 E3_activity/RING/RING 18.2 10.3
MAFHVACPITCKRICFCALGFPKSNLGSGDLFNEFSKIDEFLKDPWIIRVKEGATIQVPV
PKIVVPPPPPPPPPSQQHLLVRDDVVVSEEELLLSAQTKRVALQKKAAVASLAAEDFARR
FESGSLLEAPKDAGVEEKVSSNVKVMCRLCFSGEHEGSERAKKMLPCSSCGKKYHRDCLK
NWSQHRDLFHWSSWTCPSCRTCEVCRRTGEPNKFKFCKRCDGAFHCYCMQPPHKNVSSGP
YLCPKHTKCHSCGSNVPGNGLSVRWFLGYTCCDACGRLFTKGNYCPACLKVYRDSEATPM
VCCDICQRWVHCGCDGISDERYLQFQIDGNLPYTCPTCRGECCPVNRLEDAVHELWRRRD
EADRDLIASLRAAAGLPTQEDIFSISPFSDDEDDDLSSRKVEHGRARFSLKSLEDFSPKK
IKESGKKPSGKKYVKKKGNQMYLDGTMEVKPEDYYETQSFGSRLRDKKQASQPHPDMFFS
PASGSFSPTDRAYPNNEQGAMKHKSMDEVVENNVDKRASVLQIKSKKSNDTGVSEDVGQF
ASKPKTIKGTKLVIHLGGRNKTITNSPRSDSSSYQREQELTTLSGGNEAVSQDKIGDYQA
EKLDGTSNSDDGYRVDGAHDIKVGKRDRHIIKLGKGKSEPSGPQPHRGNGSFGQSTHFMS
SRKSNEASAVTEGLQNNLSKGEKISLRKHPDNRHVLPGDSNKSNHTSTPGLDASLKDSRP
LLRLKFKTPYPGSWAPASEEERGSVKGQRSKRKRPSSVVESPQKQEQEDVTEVQDENLMN
EIMDANWILKKLGKDAIGKRVEVHQPSDNSWHKGVVSNVIEGTSLLSIDLDDGRAKTLEL
GKQGVRFVPQKQKRLKS
>Sgl67650 E3_adaptor/Cullin_RING/DCX/DWD 209.6 24.8
MEVEGEKETMENGNSVLCQLNDPEGTQLGTAMYLPQNAGPKELQQIVNTLLNNEEKLPYA
FYISDHELLVELGTYLQKNKVSVEKAVQIIYQPQAIFRIRPVNRCSATISGHAEAVLSVA
FSPDGRQLASGSGDTTVRLWDIGTQTPMFTCTGHKNWVLCIAWSPDGKYLVSGSKAGELQ
CWDPQTGKPSSTPFMGHKKWITGISWEPAHLQSPSRRFVSSSKDGDARIWDVTLRKCVMC
LSGHTLAVTCVKWGGDGVIYTGSQDCTIKVWETKQGKLIRELKGHGHWVNSLALSTEYVL
RTGAFDHTGKQYSSPEEMKKVALARYNKMKGNAPERLVSGSDDFTMFLWEPAVSKHPKTR
MTGHQQLVNHVYFSPDGQWVASASFDKSVKLWNGVTGKFVAAFRGHVGPVYQISWSADSR
LLLSGSKDSTLKIWDIRTQKLKQDLPGHADEVFAVDWSPDGEKVASGGRDRVMKLWMG
>Sgl67651 E3_adaptor/Cullin_RING/DCX/DWD 166.2 18.5
MNRERGHAEAVLSVAFSPDGRQLASGSGDDTTVRLWDIGTQTPMFTCTGHKNWVLCIAWS
PDGKYLVSGSKAGELQCWDPQTGKPSSTPVMSTENSEDLLVVDDDTENPETADEQTECPE
ILPPETELARQEETTTQPEQEPAAFEPGHLKCITGISWEPAHLQSPSRRFVSSSKDGDAR
IWDVTLRKCVMCLSGHTLAVTCVKWGGDGVIYTGSQDCTIKVWETKQGKLIRELKGLGLW
VNSLALSTEYVLRTGAFDHTGKQYFSPEEMKQVALARYKSYNKMKGNAPESLVSGSDDFT
MFLWEPAVSKHPKTRMTGHQQLVNHVYFSPDGQWVASASFDKSVKMWNGVTGKFVADFSG
SCWTCLSNKQGLDTEDIWDIGTQKLKQDLPGHADEVFAMDWSPDGEKVASGGRDRVMKLW
MG
>Sgl67656 E3_adaptor/Cullin_RING/DCX/DWD 57.3 2.9
MKPKNSEKFQIELLDKDILCIIFSFLDLFDLVRSSVVCKSWNSIIGSSKLLHALYLKQWA
NASNSSVDMGRPLNAFLEDLALQHNRSVLVEGSVAVDQWKGHAAGVSRCRMKAGLILTGL
GDKVMRLWSSDNYKCLEEYSLSDLDPLVDFDFDESKIVGLIGTRLCIWRHNGDRCIFPFL
PGTFPKGSCMRYLDPEAFIGCADGGVRVFDMYSKRCSRIIRMHNSPVSCLALGEDQLIVS
ASVRGSITVFGQSPDQQVATLRVSNHRAVKTLCYNPSSHMVFAGSIDGYAACWDLRTMQS
VWSKWVGSEISAMQFLRNDTSTLVVGGKDGVLRILDHDTGEILTRCALDSSKAKITSRNS
LYGSIERKRVKRIVGDANIGGVIPNPGAIPYPGIILNHPGILPNHNPGIILNHPGILPNH
NPGILPNHNPGILPNHNPGIIPNPGVILNHNPRRRQSPISSLAVGMGKVVTTDNTEYIRV
WRFNKAI
>Sgl67689 E3_activity/RING/RING 24.1 4.1
MSNRILCKFFKHGACLKGEHCEYSHDWNAPASNICTFYQRGACAYGSRCRYDHVKLPQPQ
SSSGSSSSNGFSGTAISGVTTSGMAPVSSVQPEFSPISRPFHPSSKAAWNQQSVVSDTEE
EFIPQPRSNRLADQAICSFAAAGNCPKGEKCPHIHGELCPTCAKHCLHPFRPNEREEHLK
VCAKMQRHLETLKRSQDIECSVCLERVLTKPAGERKFGLLSECDHPFCIGCIRSWRNSSP
SSGMDVNSTLRACPICRKLSYFVIPSVIWYFSKDDKDEIVDSYMAKLKSIDCKYFEFGNG
SCPFGTSCFYKHSYRDGTLEEVVLRHLGTADGETVIPKDIRLADFLRNMHIS
>Sgl67767 ULD/UDP/UBQ/UBQ_PIM 84.6 0.3
MKIFVKTLKGTNFEIEANPDDSVVDVKKSIEKSQGADVYPASQQMLIHQGKVLKDATTLG
ENDVVENSFLVIMLSKNKPAAPVPAPGASSASPAPASQPQTTTTTAPAAVAPVPAAPQTQ
TQTATEPAPAASEEANVYGQAASNLVAGSNLETTIQQILDMGGGSWDRDTVVRALRAAFN
NPERAVEYLYSGIPEQAEVPPVARTTAAPTGGQAGNPLAQAPQAAVPTSGAATNPASGAA
TGPNASPLDLFPQGLPSVGSNANAGSLDFLRNSQQFQALRAMVQANPQILQPMLQELGKQ
NPQLMRLIQEHQSDFLRLINEPVEGGEGNLLSQLTSAVPPTVSVTPEEREAVERLEAMGF
RRATVLQVFFACNKNEELAANYLLDHMDEFENDDDEGLS
>Sgl67835 E3_adaptor/Cullin_RING/SCF/F-box 17.4 0.0
MSQIFDFFGNEEFYHGGSIYSNPKEAGSFLSLGIGNHVDVYFPNKRARISAPIVSGGESF
EEKKQVSLDVLPDECLYEIFRRLPVDQERSSCACVSKRWLMLLSSIPCEDLCNVNKVAAA
EAEEIESDGFLTRSLEGKKATDVRLAAVAVGSGGRGGLGKLMIKGTNSVRGVTDLGLKAV
ARCCPSLKTLSLWNISSVGDEGVVEIASGCHRLEKLDLCNCPSITNKSLLAIAKNCPSLT
SISIEGCQNIGNEGLQAIGQFCSNLKSVAIKDCPLVGDQGVASLMSSTSFVLTKLKLQGL
NVTDLSLAVIGHYGKAITDLVLSNLQNVNEKGFWVMGNAQGLQHLRSFTISSCQGVTDVA
VDAVGKGCPNLKQFVLKRCAFLSDNGLVSFAKAARSIESLQLEECHRITQIGFFGLLLNC
GPKLKALNMSSCFGFKDMILGFPLPSTQTPLRSVTVSNCPGLGDMTLAMLAKLCPQLQCV
NFNSLPCITDAGLISLIESCDAGAGLVKVGLTGCVNVNDNVVISLAKLHGGTLEMLNLDG
CGKVTDAGLVAVADDCLLLNELHLSKSAITDFGVASLARSKQLSLKILSLSGCSMLSDKC
LPFLVKLGRSLMGLNLQSCNSISSTVIDMLVERLFKCDILS
>Sgl67841 E3_adaptor/Cullin_RING/SCF/F-box 12.5 0.1
MSSIPASQTNPNPQIPQSSNSTKPKRKNKNSQKKKRNRNKNKNKKIPNWLELPEDIWSLI
FSKLYTIHIIENVQKVCSLFRKICKQPSIYKIVDMTLPDAYMDLPYDVNVMTRFIVDRSC
GCLVDIYLEYLCDDDTLMYIVERSRNLKHLRLGHYIHISDEGVVEAVKKLPELEEVELII
CSFSEAAIEGIGLAYPSLKSFSLNGVGSRHHGLVVDEEALSIAKSMPNLRNLQLIGNWMS
NEGLKAVLDGCPLLESLDLRACFHIDLSGDLGKRCEKIKHLRLPFDSTADYSHEAFTDNE
EYRRACYDSDDSGLSGMFGFCLDYDYEDYEDYEGYEDDIPLHYYGGNGFLDWGYASSD
>Sgl67842 E3_adaptor/Cullin_RING/SCF/F-box 13.4 0.1
MLLKSSSHSNSNTKFPQLSTCPKFKRKKNKSHTSKKKKTKKNNTPTLTPNWLELPEEVLS
LIFSKLNTVEIIENVQMVCMLFRKLCKQPCVFKTIDMTLPDAYMHLTFDANLMTRYAVDR
SSGCLVDIYLEDVCDDDTLMYIVKRSKNLKHLRLGHYIYVSDEGLIEALKMLPELEELEI
IICSFSADTIEAVGRTCPSLKSFALNNVGSKDHQFAGNEEALAIAKSMPNLRCLQLIGNS
MTNEGLKAILDGCPLLESLDLRACFLIDLSGDVGMKCEQIRHVRQPNDSTSDYSHQTCYD
SEKFPDYGSCDSGLDGGFFGY
>Sgl67850 E3_adaptor/Cullin_RING/SCF/F-box 14.9 0.0
MNSEVVHCDTIDRLSELPDELLIQIISFLPIKDAVRTVLLRRFGNLWTLLPTLTFDYSEE
DEDDIEVEEEEEFISNVLKFHKSPTIDQLEFHEVFFDLDDSVNECIYFAIRKKTKELSVR
GSDNLAYYDLPPCVFSTQSIVSLYLDNMAITLPPRVSMGSLKILSLTFVHFDKAALEGII
SGCPCLQELFVLDAYIIQDQLHISSPTIEKLFLSVDRDNRGHEMVIIDCPNLKILRIEQT
SLDFLRLTNVSSVFEAVIEYCPSYCCKHPKSSDQFENLLHKFCNAHLFQLEDEAYLQLKP
CGTGKLAFQKNSWVRRLALSSGNSGGCLLNICRWLKKSQRLEELVIYGDVDYFCGCNRLR
YELSAPCVMQKLKTVTIREYKKPCTTLLQLIKFLLKNAVVLDKLDCYLKIMNLRSKKHRI
GNEQGNDRDRLSELPDEILVHILSFLPIGDAVRTVLLRRFGKLWTLLRTLTYDQNTCSGR
FICKVMRYHTSPTIDKLEIRKKFGSEKEEIMEFLDYGLRKKTKDLALCYNDYFSVPRTVF
RNQSIVSLHLTKPSLDFTRKSQLHMGSLKKLELVYLCETDQRLQAWLSGCPCLQELVIKY
PFRLKALHFPAPSIEKLELDFCLRMKTPVHNLRRERYTLDCPNLKILHINEMCLETLEVI
DVSSVREAKITECCKTRGNFDYFDILLDKFRNAKLFQLGNKAYMQLQQCDSQKLGFQENR
WTRLALRSVIEGSCLLGICRLLRNSRHLKELVIYADVDFSCNCNMLLHELSSPCLMQKLK
NITIREYKKPCEGLLQLMKFLLRSAVALEKLVVVFIMKDQVNFLEGDDFIWQFSSFPRAS
RKVSVAFVKEIR
>Sgl67886 E3_adaptor/Cullin_RING/BCR/BTB 21.2 0.0
MSSQSSNSRRRSLTMERTGSLAMERTGQWVFSQDIPTDIIVQVDNSTFSLHKFMLVAKSN
YIRKLILESKESDLDRIDLSNIPGGVEAFEKAAKFCYGVNFEITVQNVAALRCAAEYLQM
TAKFCENNLANRTEDFLCQVALNTLSGAIIVLKTCEDLLPMAIDLNIVQRSVDVISAKAC
SEAMFPSRTPPNWWTDELSILGISSFEKVITSMRSRGAKTLTIASALITYSERSLKDLVR
DHSGNGIRSLSSTENSEWIIQQREVLECIVALMPSEKAAFPIKFLCSLLRGAIFLKASTS
CKNELEKRVSAIFEHVTVDDLLVLSFTYDGESLFDLESVRKVISGFVSKEKSVDVFNGGS
FREVCSGSMQRVARTVDTYLGEIAACAALSISKFNGIANLVPKDARRNDDELYRAIDIYL
KSHPNLDEIEREKVCSAMDPLKLSYEARVHASQNKRLPVQIVLHALYYDQLKLRSGENDH
GSLPEAVATRGQLHSDVSLVKENEALKSELMKMKMYISDLQKNNNNATTSRSSTSNNGMP
KKTFFSTMSKTLGKLNPFKHGSKDTSHLDDEVDLTKPRKRRFSIS
>Sgl67899 E3_adaptor/Cullin_RING/SCF/F-box 12.1 0.0
MAENNYSNRITEDVYVEDRLSSLPDDILIDIISLLEIHNAAATSVLSRRWRHLWTAVTRL
KFLDPDIKKVCPYRDWINFLDIFRQLTSPKLYALSIHHVKPVSVSCAPNVVEECVRQLRC
RKVEQIKIHINNCHARRIPVFHTSAASLFQIQTLVTLDLKCKIQLPENAPEIQLPNLKKL
HMAAPSSIPSWLGTLFSSCLLLEDLQLICYLDRYRSLKPHPDLQILLLI
>Sgl67905 DUB/USP 230.2 2.7
MSRPATRNKNKRNRPEDEVEVKSEVLRRIHTTGQVTNDDLAQLYNIRKAVCQGCRVNTKD
NPNCFCGLIPPPNGSRKTGLWQKMSDVISSFGPDPTMDLRSSDDSPAGLTNLGATCYANS
ILQFLYMNRAFREGIFSVEPHVLKQQPVLDQLARLFAQLHGSKMAFIDSAPFIKALELDN
GVQQDSHEFLTLLLSLLERCLSYSGVPEAKTIVQDLFRGIMSHVTRCSKCGQTSEASSNM
EDFYELELNVKGLKSLDESLSDYLCEEKLEGDNQYHCDSCGTRVDATRSIKLRLLPPVLN
FQLKRCVFLQKTTTKKKITSAFSFPEELDMGFRLAESSESALVYGLSAVLVHKGTAVNSG
HYVAHIKDESSGQWWEFDDEHVSNLGCHPFGEGSSCPVPKIDDTSSLEVKNSVSDQVHND
VDQRGSSNVNSHAASYSSSDAYMLMYTLRPRKVNQNGSMVSNASNANIAGTSVLANCLSL
PPHLAAEIKELNDLYLDSCEKYKSRKEQEMKSITERRQEVRSVLSEAPVPSIEEPYYWIS
MDWLRQWADNVTPSAIDNSNIECMHGKVPVSSVVAMKRLSANAWTLLCSKYNGGPCLGKE
DYCMDCLINSAHSIVSADSYKDRRACMKEVAEAALAGNSLDGKLYYISKTWLNLWLRRKA
SDNPSEADTGPTASIRCPHGQLLPEQATGAKRVLVPERLWIFLYENSNLVKPDDQLGCST
FPSDAETCTECCIELTEVASWEDTLKAVKLKQRQNHEKLALGKGVPLSSNCKYYLLPSSW
LSTWRTYINASGKNISSTIEPAPLDHVINSLICPTHSRLLERPLGLTYKRGVIMQKISAT
DGLMMISENDWKHFCEEWDGKEERGILAEVEFKSLTEGSCQEMPIAVEHMNGDQNNEMDS
REPVIKTSPEVCEECIGERESCELMKKLNYSNEDICVCFVRGKEPPKSILEASGNNFEAD
RRTSKRSRKTSFGNSKNLTVSGSTTIYQLKMMIWESFGVVKENQVVHKGSKVIEGECDTL
ADFNIFPGDMLWVTDSEIHEYRDIADELSEQKFDMREAEEGFRGTLLTSNSTSQLV
>Sgl67926 E3_adaptor/Cullin_RING/DCX/DWD 13.5 1.8
MEPPQPPSSPPSAMEEEQQPPPPQPPPEEEEEVEEEDDEDDDEDEDEEEEDEEEDVEYEG
LILKAQKFMELITSSPDNPNPKALHGLASLLESQESRYMEEADHSSSNDTRASHNIGRLG
SLIRENDDFFELISSKFLSESRYSISIQAAAARVLLSCSLTWMYPHVFEDDVMENIKDWV
LEDSSQNSGDDGLWKRQFGDSKCSDFDMRKTYSIGLLALCLTSGSQVIEDVLTSGLSAKL
MRYLRNRFLGETSGSQKVASRVAESRSVPLGGVGKGRDESHPRSRPTLESASLDDSRVED
GGSADLGCQRDFDRSFNRQLHGEERRISREPPDGLAEEVDIYDADIDGEVCRRGGDVHDG
RLKTSDRNGPGRYLHDEDYDGSERDDSSRYRLSRGLVRFRGKTRASETNTDPEQHIMSPG
SGSRGGQIRSGRERSSMRNLDGKRVTDSKKNLNRTSAESTGIEREETDECIQECRVGSKD
ISDLVKAAVRAAVAEARAANAPTEAVNAAGEAAAELVKSTAMDEFKSTNDEEAAFLAASR
AASTVIDAANATEVSRNPNSVNADLPNDGAAEAETNEDIEFFIPDSDALAQQREKYSIQC
LMLLGEYVEVLGPVLNEKGVDVCLALLQRYSDEKQKTEIVSFLPDVLKLICALAAHRKFA
AVFVDRGGIQKLLAVPRVLHTFFGLSSCLFTIGSLQGIMERVCALPSDVISKLVELGLQL
LECPQDQARKNAALFFAAAFVFRAVLDAFDSQDGLQKSLGLLHDAASVRSGANSGTLGAS
APGVLRNDRSNADILTSSEKQIAYHTCVALRQYFRAQLLLLVDTIRPNKSNRSTSRNIPS
SRAGYKPLDISNEAIDAVFLQIQKDRKLGPALVRARWPAVERFLACNGHVTMLDLCQAPP
VERYLHDLLQYALGILHIVTLVPNSRKLIVNATLSNDRVGIAVILDAANGPGYIDPDIIQ
QALNVLINLVCPPPSISNKSPLLAQNPQSASVHTSNASTEARDRNAEARERNGEPSTTDR
GSSMNITMQSPSSNLASGLVGDRRISLGAGAGCAGLAAQLEQGYRQAREAVRFNNGIKVL
LQLLQTRVVLSPAILDCLRALACRTLLGLARDDTIAHILTKLQVGKKLSEVIRDLGNQNP
GTEQNRWQTELTQAALELIAIVTNSGRASTLAATDAATPTLRRIERAAIAAATPITYHSR
ELLLLIHEHLQACGLSSSATTLMKEAQLTPLPSLSASPSLAQHACVQEMPSIQIQWPSGR
APDGFLNNRSKITQNEELHSKGDSAFSLKKKPVLFSPSFSARTKGRPSTEQQTSSISKAL
GSSKRTLGSAAPLEPSSAPTSEKTDDAEIHTKTPIVLPMKRKLTELKEVAPGSSAKRLNS
NDHGLKSPVFQTPNSTRRGNLLSDLYGSFTPSSSARDLHGRQAPLAGQADGFDDSQYNDT
SLSSNQPRLLSDSQPVNSERLTLDSIVVQYLKHQHRQCPAPITTLPPLSLLHAHVCPEPR
RSLDAPSNVTARLSTREFRSMYGGIHGTRKDRQFVYSRFRPWRSCRDDAAALLTCMTFLG
DSSQIAAGSHSGELKIFDTNSSNILENCTSHQNPLILVQSSPCNKTQLVLSSSTIDVKLW
DASSISGGPIQTFEGCKAARFGNTGTCFGALPTDTSQREILLYDVATKQLDRRFSDTSSG
PSGKSVYSILHFNPSDTMLLWNGVLWDRRVSGLVHRFDQFSDYGGGGFHPGGNEVIINSE
VWDLRNFKLLRSVPSLDQTNITFNSSGDVIYAILRRNLEEMSSANFTRRSKHPLYSAFRT
LDAVNYSDIATIPVDRCVLDFTTEPTDSFVGLVTMDDQEDMYSSARVYEIGRRRPPDDDS
DPDDVESDDDDDDDDDDDVDLDPLLGTDFDIDGGSDGDMSNDDSATDDDDDDDDDGDFLV
DGAGFDVGGGEILDMVTEGDEDYDSDMMGSFSSGDGFV
>Sgl67950 E3_adaptor/Cullin_RING/SCF/F-box 22.3 0.0
MMMSKKTKNMMDSLPEELIIDILSRVPAKTVGRCRCVSKPWNSLLSQPEFLKTHLNKTQQ
SNLVQESLILENADGRSLYSAQLNNVFDEITIKATNLNFIDNLFDSTIFVAPICNGLMLV
GDFQNKVYLINPLTKETKQLPEITYPVRPHGQCVSSFGVGYDSMTDDYKVVFIFSVYIRH
YDEDMMHEYDLLYIDKIANVYSLRNNSWTVAEIPPNYCGCCLSKSGVYVNGFMHWVTRSV
SKKYAVILTFDLRNEKFGEMQRPFSEYSNNFHFGYYNIHRVGGFLCVRYILGGGVIESWR
MEAYGVFESWTKCLIVYPHQCKMLPLCLMPKQQLLLAKDLCNFRFMGQKLVVCDLKDGSL
KDIQVHGTPDGYSAEWTFIESLVSPHHG
>Sgl67954 E1 220.1 0.0
MDGEQLTEQETALYDRQIRVWGADAQRRLSKAHVLVGGMMGTIAEFCKNIVLAGVGSVTL
VDDRRVTEESLTANFLIPPDEKLYEGRSIAEVCCDSLKDFNPMVHVSVEKGDLSKLGTDF
FEKFDVVVISCCSLSAKKAINEKCRKLSKHIAFYSVDCRDSCGEIFADLEKHSCTKKQAD
ETVECVLHYPSFAEAIAVPWKSLPKRVSKLYFAMRVIERFQDSEARVPGETSAADLPSVL
KLRKELCEAQLFSESQIPDCLLQRLLCGKLEFPPVSAIIGGILGQEVIKAISCKGEPIKN
FFYFDAVDGKGIIEDISNPNPVT
>Sgl67995 E3_adaptor/Cullin_RING/SCF/F-box 17 0.0
MSSSSSNRWKSTQNDTNDDDTVDWLELPSDLLIQIAENLRSVEDYVAFSCVCRCWRNAIS
GCDMNKLRYNWGHHQMPWLLLTDGNQKILDTSSHNWVQRFQNPWVLVIGDDIEEILETKD
EVLLLLLNDEEELMMDNNGKSYKRSMLNLNNGNTYTVNCPQGYRRNCWGSSHGWIFAQDN
TPNLCVFNPVTNTRLDLPPKTTLPLRLELVNSYAITTAAIFNRVLPSDNDDVPGGRAEAE
GDPTSLFVVLIYNFYTTIVFAKPGDTEWTEIGYTSPGEHLLDVSYGNGRLIVLGEMGAIG
YCDLERSHQQQQQDLDEPLGLTWYDCNLELLRNQQSLGIDKPFLLSDYTTYLAHCGEDLL
LVVRMLLIDKNTRNVNYANENYWTFKFRVYKFLIGDEQWEELEDLGDVALFVGSNTTMSV
CASDVGCQPNSIYFTDDSKHCYTLTQDRLGGADMGIFRMADQSILPLDLKNNNTHTRSYY
CCPLWFIPTL
>Sgl67996 E3_adaptor/Cullin_RING/SCF/F-box 13.5 0.0
MAPRSVLKHRDKNRSNNDNNNNNNVDWLKLPSELLVQIAEDHLPSVNDYVALSCVCRCWR
NAIKSGCDMNKLRYNWAHHQMPWLLLTDGNQKILDTYCYNSEPILTNPEDELLLHDEKEL
RVDNGKSYKRSMLSLIDGNTYTVNCPQGFRRKCWGSSHGWIFTQDNTPNLYVFNPLTSTR
LNLPSILSLVPNFFEKKVIKRAAIFKVPSDDDVPRAAGDPSLLVVVIYGNFPSNVAFAEP
GDTEWTKIDDTNKVGVILDVSYSGDQARGRLVVLGTMGVLGYCDLDRHQGHPVRLTWYDC
KLGFLNQPFWVLDSFLADYNVYLVHRGEDLLLVVRILKLDEHRRGEDYVYDNYSTTEFKV
YKFVCDNKQWKELKDLGDAAVFVGSNTTMSVCASDVGCQPNSIYFTDDSKHCYTLTQDRL
GGRDMGIFRMADQSVLPLDLKNNTHIRSYYCCPLWFIPTL
>Sgl68006 E3_adaptor/Cullin_RING/SCF/F-box 15.1 0.0
MELKSTQNNTNDDNIVDWLELPSDLLIQIAENLRSVEDYVAFSCVCRCWRNAISGCDMNK
LRYNWGHHQMPWLLLTDGNQKILDTSSHNWVQRFQFPWVLVIGDDIEEILETKDEVLLLL
LNDEEELMMDNNGKSYKRSMLNLNNGNTYTVKCVNCPQGYRRNCWGSSHGWIFAQDNTPN
LCVFNPVTNTRLDLPSKTTLPLRLELVNSYAITTAAIFNRVLPRGRAEAEGDPTSLFVVL
IYNFYTTIVFAKPGDTEWTVIGYASPGEHLLDVSYGNGRLIVLGEMGAIGYCDLERSHQQ
QQQDLDEPLGLTWYDCNLELLRNQQSLGIDKPFLLSDYTTYLAHCGEDLLLVVRMFLIDK
NTRNVNYANENYWTFKFRVYKFLIGDEQWEELEDLGDVALFVGSNTTMSVCASDVGCQPN
SIYFTDDSKESYTLTEDRLGGADMGIFRMADQSILPLDLNNNNTHTRSYYCCPLWFIPTL
>Sgl68020 E3_adaptor/Cullin_RING/DCX/DWD 70 1.3
MGKDEEEMRGEIEERLINEEYKIWKKNTPFLYDLVITHALEWPSLTVEWLPDRDEPPGKD
YSVQKMILGTHTSENEPNYLMLAQVQLPLEDAENDARHYDDERSDFGGFGCANGKVQIIQ
QINHDGEVNRARYMPQNQFIIATKTVSAEVYIFDYSKHPSKPPLDGACNPDLRLRGHSTE
GYGLSWSKFKGGHLLSGSDDAQICLWDINATPKNKTLDAMQIFKVHEGVVEDVSWHLRHE
YLFGSVGDDQYLLIWDLRTPSATKPVQSVVAHQSEVNCLAFNPFNEWVVATGSTDKTVKL
FDLRKLNTALHTFDCHK
>Sgl68024 E3_adaptor/Cullin_RING/DCX/DWD 39.4 0.6
MCKRPCVPLVLPVCWEEVFQVGWSPKNETILASCCLGRRLMVWDLSRIDEEQTQEDAEDG
PPELLFIHGGHTSKISDFSWNPCEDRVVASVAEDNILQIWQMAENIYHDEDDLSTDDAAA
TKGS
>Sgl68033 E3_activity/RING/RING 27 0.0
MFMAFQCFYKRGPQKSSGGGGDVKPKIKSSEIVEVQLNSNWDDVTCPVCLDYPHNGVLLQ
CSSYEKGCRSFVCDTNHLHSNCLERYKSAHGIHAGSNSLSTAYAVASENSEPVKPENNGK
PTCPLCRGEVNGWVVIDKAREYLDQKKRCCEEERCSFVGTFLELQKHAQEQHPDSRPSKI
DPARQLDWENFQQSSEMVDVLSTIHSEVPHGVVLGDYVIEYGDDDTADEFEDYSQNEGNW
WTSCILYQVFDNLRSNRNRRRSRTSDRRRGSRRSSNDTSNSDDGSVTSVEFPDYRVDETD
DDFVNSRGPGRSTFNHRSSRRRRSRFYDH
>Sgl68035 E3_activity/RING/RING 27 0.0
MFMAFQCFYKRGPQKSSGGGGDVKPKIKSSEIVEVQLNSNWDDVTCPVCLDYPHNGVLLQ
CSSYEKGCRSFVCDTNHLHSNCLERYKSAHGIHAGSNSLSTAYAVASENSEPVKPENNGK
PTCPLCRGEVNGWVVIDKAREYLDQKKRCCEEERCSFVGTFLELQKHAQEQHPDSRPSKI
DPARQLDWENFQQSSEMVDVLSTIHSEVPHGVVLGDYVIEYGDDDTADEFEDYSQNEGNW
WTSCILYQVFDNLRSNRNRRRSRTSDRRRGSRRSSNDTSNSDDGSVTSVEFPDYRVDETD
DDFVNSRGPGRSTFNHRSSRRRRSRFYDH
>Sgl68038 E3_adaptor/Cullin_RING/SCF/F-box 15.6 0.0
MIHQQEILEDILSWLPAKSIGRFRCVSKAWKTLLSQPHFIKTHLNRIKQSPFGVQSLILA
NYQSNSLFTTHLNDAHHMFDEMTVVATPLCFDDDDHKFNIELIVYAQVASCDGLTLFEDE
ENRLLLVNPTTKEFKELPKSPFAFDPDVSSYTLFGVGYDSVSDDYKVVMIFFYNNDNDLN
AHRPDANEVFVNVYSVKNGTWKRAANSPYDHAVGHITSGVLVDGNIHWLASRTSDYSSVI
VGFDLGEEKFQEVPPPSLVEGSKFVLNRLSTLGGNLSMYDLRYLDPQTNVWVMKEYGVKE
SWTKFTIVDTQKKSVFRPLCLLGKEQVLVKDEETDEEKLVMYNLKDESFKDVVVQGIADE
FGVGGTFMETLVSPHCSAEATREE
>Sgl68039 E3_adaptor/Cullin_RING/SCF/F-box 16.5 0.0
MNTRKSSNHSNMPNLPQEIIIDILTRLPAKLVGQLRILSKQWKTILSEPQFIKDHNNYVQ
TKLKYEEESQSLIVACNNSLYSIALINVNNINNHGFHDDNIIFVATKLAFADHLFTAASI
YATAYCNGLVLVADEKCKLSLINPVTKEVKQLPGLACFDPYSHFYPSFGIGYDSVSDDYK
VVVFCYMCIDKRIVNVYSVRNGMWKQVESSPNNDCFICASPSGVYFDGNLHWLSISNGYG
GVLAFDLHEEKFHQVPTPSLLVGFLSNENFNVVMVGGCLGVRFVNKWTTFWRMEEYGVKE
SWTKHLIIAPKKHKRSRHVCFIAKEKVLLTEFGDGLTGNSQLVMCNWKDGTFRNIVVLGM
SGKVYVGQTIVENLVSPHGCKV
>Sgl68040 E3_adaptor/Cullin_RING/SCF/F-box 14.2 0.0
MIHQQELLEDILSRVPAKSIGRFRCVSKSWKTLLSQPYFIKTHLNRIKQSPFEVQSLILA
NYRTDSLFTTHLNDAHHTFDKITTVATPLCFDNEDHKFNAESIIVAQVASCDGLALFVDK
EKRLLLVNPTTKEFKELPKLPFALDPDFWSFTMFGVGYDSVSDDYKVVMILFYANDIDVY
AHRTDDASDVFVNVYSVKNGSWKRAANSPYNHAAGLLPSGVFVDGHIHWIATRTLDNSSV
IVGFDLAEKRFREVPPPSLVEGSDFLFHSLLTLGGNLSMFVTTTLDPQTNVWVMKEYGVK
ESWTKLTIVHTQEDSTFRPLCLLGEEQVALVKDEYSGEEKLVVYSLKDESFKDVVFQGNV
DDFGVAGTFVKTLVSPHCSAEATREE
>Sgl68042 E3_adaptor/Cullin_RING/SCF/F-box 15.7 0.0
MIHQQEILENILFRLPSKSIGRFRCVSKPWRALLSQPSFIKTHLNRIKQLSSPDQQQPLI
AANYKGCSRSLYSIQFRNVDDETAAAFATNLISEYDQPFESKTCVIVQGSCDGLTLVQDY
KKLVLINFTTKERKELPKRAPYAPDGNGRGSDDNVVYGFGYDSVSDDYKVVALSYYNAFI
HIEPKKCTQMCVDIYSVKNGTWKRADNSPYDYCVAQSSPGVVVDGYMHWFACRISDYSYA
IVAFDLGDETFREVPLPDSCTSDDMDVYNLTTLGGCLCMFDMWISYKTEFWVMKEYGVGK
SWEKFRIVDAENYYSDREPLCLFGTEQVLVQKRQSLLKKLVMYNLKDGRVKGVVVRGIPN
VVDVRGTFMESLVSPHSNVEAAREEE
>Sgl68044 E3_adaptor/Cullin_RING/SCF/F-box 20.7 0.0
MNSSKVTNSPEHMLPQDILIDILSRLPAKSIGRFRCVSKPWKSLLSQSQFIKTHLNRTKQ
LFGEDEASLLFVSDDSGSLYSSHLKYAHHLFDEITISATKLCFDDHHFSSTQLCEMGSCD
GLVLVMDREDTVFLINPTTKEIKELPASPYAPNPRLSGTQYGLGYDSVNDDYKVVSISYN
CNCHGNDHGFCDMFVDAYSVRNGTWEKGPQKKLEGVRLSDTSFVITAFDLGQGKFKEVSP
RGVLVLGDQNFGFNHLVELGGCLSWYPSSCFPSNAVDVYMMKEYDDNNSWTKYSIIHPEP
IRVRPLCLLGKKELVLLKNEDCFDQNLEMYNLERGTSKDIAVLGIPSAFSVGGGFIESLV
SPHCSIEAVRKC
>Sgl68046 E3_adaptor/Cullin_RING/SCF/F-box 16.9 0.1
METPNKLRKMIHQEEMIHHEEILEDIFSRLPTKSIGQIRCVSKPWKTILEQPHFIKTHLN
RTKQPPIEVQSLILIGHYPNSIFIIQLEKPEQMVDEITISATSISLDDHRFDNESIIGSL
ASCDGLTVIEDDDRLLVLVNPTTKEFLELPESPFALDPHISFSMYGVGYDSVSDDHKVIS
ISYYDSDYEFESEPDCSEMFVTVYSVKTGTWKRVRNSPYDHAIGKLTAGVLVNERIHWIT
CRKSDCSSVIIAFDFGTEEFREVPPPFWAEGKRIVYYELLTLGGWLCMYSANKVFKSDIW
VMKEYGVQESWTKITIVDPLMSEFRPICMLGTEHMVLMKDEETINEKVVIYDMNQAKFMN
VVVEGIPTAFCVGGTFMESLISPHSSVEALIEE
>Sgl68047 E3_adaptor/Cullin_RING/SCF/F-box 16.9 0.1
METPNKLRKMIHQEEMIHHEEILEDIFSRLPTKSIGQIRCVSKPWKTILEQPHFIKTHLN
RTKQPPIEVQSLILIGHYPNSIFIIQLEKPHQMVDEITISATSISLDDHRFDNESIIGSL
ASCDGLTVIEDDDRLLVLVNPTTKEFLELPESPFALDPHISFSMYGVGYDSVSDDHKVVS
ISYYDSDYEFESEPDCSEMFVSVYSVKTGTWKRVRNSPYDHAIGKLTAGVLVNERIHWIT
CRKSDCSSVIIAFDLGTDEFREVPPPIWAEGKRIVYYELLTLGGWLCMYSANKVFKSDIW
VMKEYGVQESWTKITIVDPLMSEFRPICMLGTEHMVLLKDEETINEKVVIYDMNQAKFMN
VVVEGIPTAFCVGGTFMESLISPHSSVEAPIEE
>Sgl68050 E3_adaptor/Cullin_RING/SCF/F-box 18.3 0.0
MIHQQEILEDILSRVPAKSIGRFRCVSKSWKTLLSQPHFIKTHLNRIKQSPFEVRSLILA
NYQSKTLFTTNLNNAHHMFDEMTAVATTLSFGDNDHKFNAELIVYAQVASCDGLALFEDE
EKSFSSIQLHSSVSSFDLHFTNSQIGNRFFQLSDPAATAADQANKEEVDSRSVFVGNVSF
FCPRKYRFRRLQSDIIC
>Sgl68051 E3_adaptor/Cullin_RING/SCF/F-box 18.5 0.0
MVYIPEELIIDILSRVPARTVGRCRCVSKQWKSLLSQPEFLKSHLNKTQNSNLVQESLIL
ANIDLRSLHSGQVNVFDEIITINATKLDFINPLFNTRIYVAPPCNGLILVVEEDKNKFYS
YLINPLTKETKQLPKLTYPDGKHGFLPQYVSLYGVGYDSVSDDYKVVVIFSFPFGYYEDA
YDESYDRMYLENIANVYSLRKDRWTVVENPLVYCGFLSPGVCLGGFIHWSAIKVESDSEY
YSESDVTLTFDLRSEKFGEILSPGSKDYHGYYQAEVQRLGKYLCVYYVLEDRDQILELWR
MEEYGVVESWTKYLILDPDRFSLVPRAGAEAPALLVPVCLMPKQQLVMGKDLFRFYGKDH
KLVVYDSKDGAFKDIQVHGTPAIGYSANWTFIESLVSFNELASL
>Sgl68054 DUB/JAMM 31.8 1.3
MDPNTLTSSAEIAKQTWELENNIVTMDPTSTSTQTQSSSSSSNPQNTDASDAIFYYDEAA
QSKFQQEKPWVNDPHFFKRVKISALALLKMVVHSRSGGTIEVMGLMQGKTVGDAIIVMDA
FALPVEGTETRVNAQADAYEYMVEYSQTNKQAGRLENVVGWYHSHPGYGCWLSGIDVSTQ
MLNQQYQEPFLAVVIDPTRTVSAGKVEIGAFRTYPDGYKPPDEPVSEYQTIPLNKIEDFG
VHCKQYYSLDITYFKSSLDCHLLDLLWNKYWVNTLSSSPLLGNGDYVAGQISDLAEKLEQ
AENQMAHTRFGSILAPSQRKKEEEPALAKITRDSTKITVEQVHGLMSQVIKDILFNSVRP
DQSQAESSEPEPMVEA
>Sgl68063 E3_activity/RING/RING 24.9 5.2
MEENSRKRSSGGLRRGTSLVLRDSAEKNRDRNVQVCSRVGCSSKLHSMNDTQIGSPSKAK
TPKKPFGSSALGKETIGSSSKTLASPNTSRKSFSETKKKLPSHLDTDSETSSLHDESEKM
SGKTRMRVHPEPEDQDPVEARSSGAGSSSGGPSNRFVKRNTPRFGLGRQDSAASSSSSVA
LKQANQGVRNGGTSSNKYNLRQLKCNSISDVVPSSSSPSSESNLSRKDTGGRKRIGEAES
SLSVRGKKIYGSTKDDRKNDTSNRGISISDSRRNRSSSPGNNVATSIRTRRLSSRTRLSN
QESRDVLPLVESPLMNPSSPHSDLATDAIDFNLENHFSGQTTASPLSSFRRPGSGSEHVR
PNRPVGPYEAGISRSLMNRDSLRQYNLDGIAEMLLALERIEQEEEPTYEQLLVLETNLFL
GGLGFHDQHRDMRLDIDNMSYEELLALEERMGTVSTGVPEDVLGECLKTSTYQGIAECRE
DENDVKCSICQEEYATGEELGRLSCDHRYHNECIDQWLRLKNWCPICKTSVAPSPSASLP
P
>Sgl68094 E3_adaptor/Cullin_RING/SCF/F-box 17.6 0.0
MRIWCCLPCFVVDDRENAMDGAREDEIKSENENLDEENEANEEEKLSSEGLSLELGLPGS
SSSSNNDKSVEGLKGGSKRDLGGFVVEREKSDLESLELSIGGSSSHHLNNLNELDFSLCS
NVNEHGNASFTTPVIEFDFDLYIKRAKVESEFNKSHYSADSPTFTDNNVDVIRRNMISPN
SSVCTRNNIECITHPVDDSVNTVIRDENGDIIEGSTDSSDMEDMAIPLDLSDDLLHMVFS
FLGHANLCVAAMVCKQWRAASAHEDFWRSLDFENRNISVAQLEDVCHRYPRATEVNLCGN
PDMHMLVMRAVSLLRNLEALTLGKGQLGESFFHALSDCPLLRKLVVSDAALGNGVQEISI
NHDRLQHLQVTKCRVLRVSVRCPQLGTLSLKRSNMAHVVLNCPLLHNLDIGSCHKLPDAA
IRSSVTSCPLLENLDMSCCSCVSDETLREISQACANLRELNASYCPNISLEAVKMPLLTA
LKLESCEGITSASMTAIAFSNMLEVLGLDFCNLLTSVSLDLPHLSNLSLVHCRKFVDLNL
RCLMLSSLNVSNCPALHSISITSNALKKLALHKQESLNSLSLHCQYLEEVDLSDCEALTD
SVCDVFNDGGGCPMLKSLVLDNCESLTTVGLHNTSLVSLSLAGCRAVTILDLKCPYLEHV
RLDGCDHLERASFVPVGMRSLNLGICPKLSALHIEAPHMVGLELKGCGVLSEASINCPLL
TSLDASFCSQLTDDCLLRTNASCPLIDKLILMSCSSIGADGLSSLCWLKNLTYLDLSYTF
LTDLQPVFNSCLRLTVLKLQACKYLNDSSLVALYTLGALPALRELDLSYGTLSQSAIEEL
LAYCTHLTHVSLNGCKNMHDLYWGFTELSRYQPSGLSSSQLINEPVELPRRSIECLTCVG
CPNVKRVYIPSIAQCTHLSSLNLSLSHNLKEVDVACSNLCFLNLSNCNSLEILKLDCPKL
TSLFLQSCNIDEETVESAISKCTMLETLDVRFCPKISAAAANNFRAVYPSLKRVFFGSR
>Sgl68102 E3_activity/RING/U-box 26.7 0.8
MASTVRFKFRSAATFDSVEIDDNQSSISIRDLKSKIVLKKHLNLCQDFDLVFSDSISGIE
YTDENTRIPSGSSVIIKRVPAKSPPLLRASDTSTGCLGARDANCVGVFDQPTMDIGVNDF
DDFGVDLCPPPHISLSDTAEKLQFNNNGKKDKVVSRCSQELLASCQKIESAHHAQSKPKD
SSANEESTLVMPKPKIEEQPLPERFPAKHSAMENSSMPSELKCSLCRTFFKEAVMIPCCQ
HSFCGNCIRAALSDNAKCPMCSSTKCKPEDLLPNVSLRQAIVRFLESQPLLNGSENDLQR
YAPDGESGIQVMDVSSATTIPPRLQLRSNKVMQSKLHDRAHLADKCTPDTLEDFSEFEGE
NDPQTMVHRTKEAVSCSKKEEEPSAFTRGGERNFAAPGRPNKGPRTCYMCGSPDHLIRDC
PGAAHCSTSQWNGVASLPGTVSGYPPSYWPGSSPHSRPYINMYGSPGMMFYNAATAPISP
FAYPSYAPSMYGGYPVSNYGNVGGLTLPVGNIAMQPRHVEHLELQGCTKQQRNKEFDSER
DWNHNREHNVNTQHDFVDRGPHHSGDGFARRAEGKHKSRDNPDGDDTNLICDRQGNAAGH
LGCGRDLRIPQSDKSSSETDLLKDRVRVREDKHKKFHRTYRRNDEIEKNYGRDSSQKHYQ
PKKESGKRKRMEHDERKSDRHSYSRSRSSLERSYSGGDARKRRDDSTHKSRHSKYNGKEM
HHDRGR
>Sgl68106 E3_activity/RING/RING 26.9 14.2
MGDSTQSQMEATTSSSSSSSTQAEGVLRGFAAAAPPEIMRAAEKDDNYASFVSDACRDAF
RHLFGARVAVAYHSETKLLGQMLYYILTTGAGQQTLGEEYCDIVQIAGSYGLPPTPARRA
LFILYQTAVPYMAERMSSRIASRGMFLAESHSDDFGDRDALTGSHLSSETSSSSTSQISD
SFFSSLKERYRRLRLYIIQRWPTMLPVVRDVLQLFLRTNLMLFYFEGLYYHISKRASGIR
YMFIGKPLNQRPRYQILGVFLLIQLCVIAAEGIRRTNLSSLGNSVQASLGTYNHSTGGGL
PVLNEEGDIITADSDKGKGASKCTLCLGNREHPTATPCGHVFCWNCIMEWCNEKPECPLC
RTPLTHSSLVCLYYSDF
>Sgl68175 E3_activity/RING/RING 19.6 0.0
MVTLMIMSLVWCNKAVTFFFNKFRTLDVSHLVYMVLMIKVNADVDVATAMDYSYEDEDED
DKSEKIRSVVRFCLEEFDKRGKNNIDGKQEDGDGDAAALPCSRVLHTDCLVPWITKGKNT
CPIPNKTIVPKRANSNPPTSTPNYGLKVKTHISSSSSFSENPTFAAAPSLSLLVSMAPPA
KDGKKADPKAQALKAAKAVKSGSTTLKKKAQKIRTKVTFHRPKTLKKDRNPKYPRISATP
RNKLDHYQILKYPLTTESAMKKIEDNNTLVFIVDLRADKKKIKDAVKKMYEIQAKKVNTL
VRPDGTKKAYVRLTPDFDALDVANKIGII
>Sgl68214 E3_activity/RING/RING 36.4 7.5
MSFINRPRVVINGTRRKRTYRFFWCRQCDRTVRIASANSSTFVCPFCYNLLLQEFHLPRS
SSFPSHNSELPSSSSSSSSSPSPAQLIDTMSQIINMPPQPRPAPLPPQENTLSNQPEPSD
QPVQDQTNENRTRSRITEFKLTADTMCTEPPCPICKEDFVVNEHITKLGCNHLYHSDCIT
PWLQINSTCPVCRYELPTQPGCTHHDHNNRVRSSSSNNNNNFRAANYGHDYEFYGDFNLR
FEEVMNLSIPSWAELFSILWPFRLGALLDWSFPS
>Sgl68256 E3_activity/RING/U-box 57.2 0.0
MGSGKHRWKISIYRTPLSSSTTTTSKTQNSKPPNEFLCPISGLLMGDPVIISTGQTFERA
CVIACKKLGFIPTLNDGCNPDFSLVIPNLALKSSIDNWATASQLSPPKPLEFDDGLKVVK
SLMAAKAKEVRVTAELERVNSNPGSNPLEHAESELSRRQTRFGSTDSLSGSFRRTPLVLT
TRPSCYSSCSSSSEFELPESGTCEDDAYVSKLRSPHVYEQEEGIVGLRKITKSSVDSRAG
LCSPRLLSALRSLITSKYTDIQVNSVAALVNLSLEKVNKVKIVRAGFVPPLIDVLRGRFP
EAQEHACGALFSLALDDGNKTAIGVLGALQPLVHVMMRSESERARHDAALALYHLSLVQS
NRLKLVKLGTVQILLNMVKLGQMSGQALLILCNLGAFSEGRAAMLDAGAVEFLIDMLRKD
KFDSESTQESCVAVLCALSHGGGLRFRGLAKLAGAIDVLKDVAEKNSRERAKEKARRVLE
LLKAKEEEEEDVDWEKVLESGFPGRATTGQSSRNSTEF
>Sgl68366 E3_adaptor/Cullin_RING/BCR/BTB 54.8 0.1
MQSNYPATKKLCSEVLILSCEPIIKSIICALTISSMHPVKFSSQEETLMLEACHLALITR
WSGKHHNFFWRLRGDKVLAHLLVRNLQNLYPHQQSLSVEELIKVTREGLAANFHLDMRPY
VWEIIGWLSAQCEEDFSPNKNDHCLRILVATACLAFVDSIGRERLLRQGDRKYTLRSISA
AKATLMMLYSPCKYISSEAKLLLLEVLRSDGEEYLKQLLHALDFVYSGDMSRKPDKAQIF
ISLVGLTCYSGLPRFCKKVVRNGGIKTLLGYIKWWIDNVSHTEKVCLTSHLKVTSMERTC
CIIDAEDWEGNEAHLILALWSLAELINSHGMEGCELDIFSRQKIYEKEQFIQDIQQISVD
STCTGLRWYCSYLLSLFGYYGFPSKLGKSIASFCEKDYGDMRLVLRDGQYLNVHQVILLI
RCPSLLPGYPSDEEKMSKSNNSPARQVTEKCRTKEVTLSAQVDQEAMSKLLDFVYSGYLQ
AQGAIVKKLRLLAKHCNIQPLLHLLCRKRPKREVPVPRFDLTTALGPIGHEFSDIMLEAK
STEDTGRVCSCCYHSMPHIHAHRAILSSSCDYLRALFQSGMQESRSESLKVPVSWEALCK
VVIWLYSYNLPKPVSGCLWANMDVQQKMLELQPYIELCWLGEFWFLDDVKEECSSLITSS
LDSPTLAIKVIKVAAHFTQWELVNVAANKIAPFYRSLHSSDALDVLDEALVEIIRLASVQ
LAQESV
>Sgl68373 E3_activity/RING/PHD 39.1 22.5
MKLTELESPTIMAAKPSSSSSSSSSSHHHHNHSQNHNNSITTNNHNHNHQPLSIDLNEVP
SFSETLINLSPTSVVRSIHDVPKYAEGVAAEIPDDAGPCAGCGGGLTDVERLVCDGCERA
FHFACSGVASLGVEDWVCRVCVSEGVSSRRWRLGRKDEGGVRLLDMNASPPSDCDAGEAL
AVAAAAAGAASGSGSRQLCFGDNTFGGNASGGLLSYPNLICSSNGFGFQKEPTVVAHKLR
LDFQDILQSKWSTARNFDDIKHGSQLGRLRSTGTTFRLPSWNSSEVLQSLREFISERHGI
LDEGWRVEFKQSKNGCESYAVYCAPDGKVFETMSDVANYLGLVSNGNPLEPETRSDHGST
LRKNGLNPPKRRKLTKIPTGNGFMESKDSLMSGCKDGFFSNLQKESFMSKDEKKVEVTEG
VQEENDVNDLHHFHEGLPLQYEDFFVLSLGKIDARTSYHDACKIWPVGYRSCWHDKITGS
LFLCHVLDGGDSGPVFKVRRFPCSALPIPYGSTVLQRQRGICLNNPAKAGEKSTPSEEES
CIAMLLSDPCFSPEDDSMSWLLSSPNEVVGQKEIRSSHEVNSTCDRSQDLLAHNSPTGEK
IGEFSVDGRSSSIVWSILSQKLADACRQTYKQKGSLKFFCKHVEDGMSSFYDIMTCRNKG
VFSSLDKFCSLLGSLKVPLVVTSDDELDPTIEALKNWLSLDRFGLDVEFVQELIEQSPDF
RRCLHYESLRKRSDCSTAPLVRNGLLLINGKSMEQCKQDISLYGCYKEYRTIEEPDISIH
IRPPGNSVGAKLPPHLVGDVLQVWELLHRFHDVLGLEPQNFNELEVELISPWFESLPQHG
SCERDSPVIHGPGIPSEHTSSSSDIAVLEENRFIEMQSAAVREHAHASLAFSTDNNCSNV
SLRKAHMSLLDVIVSELQIKVAAMVDPSIDAESKSRRGRRRDVDSSILAIRPKLNLLPIN
ELTWPELARRYILAVVSMDGNPDSAETGIRECGKVFRCLQGDGGVLCGSLVGVAGIEADA
LLLAEARKRIYGCLSSGNDQLIMEDDNAEPVGASGTMNSGEGKIPEWAQALEPVRKLPTN
VGTRIRKCVYEALEKNPPDWARKTLERSISKEVYKGNASGPTKKAVLSVLVDVLNECSQQ
KVLEERKRTTIVSISDTIMRKCRILLRRAASADDEKMFCNLVGRNLIHSSENDDEGLLGS
PGMVSRPLDFRTIDLRLAFGAYSGSPESFLEDVRELWKNVRVAHTEQPELVQKAERLSEN
FETLYEEEVVALVDKLKEYSEMEQLTAEAKKEIEDILASTSNIPKAPWDEGVCKVCGIDK
DDDSVLLCDTCDAEYHTYCLNPPLARIPEGNWYCPSCVFGVNMLESSSKGIPFMGQRHRR
KNHGEGIRSYLEELARLATVIEQKEYWEFSVEERILLLKFLSDEVLNSILIRQHIEQCFE
TSADLQQKLRMLFSEWKSLKVREDILATTATCTELQPTVTERCDQIHSVSDKAQVRGDTG
FLQSTNHISSQNVKHMEKINSSETHVKQLVDSGCQMKDPVEVVNKNVGSVKKDEHERSSK
RLKKSSQKKDCSDLDAIPPETSVMDSESCQDKKHEHGMPDVPAVCRSEDMRGVTVSSCPV
KSGSAEDVSCPTSTVLQASNLELSAVQNELSALHKSIANAESQLMKSSVRMDFLGSDALG
RLYWASSLPGAHPRIIVDCTISNQHTTQHGGHARRGGEGIFFETSSSVSNSQEGSSVACP
FVYGHDCSRPSSSQWVYYQSQEEIKELIKSFKLKNPKERELKDSILNWQKLRCHELHQTG
IQEKIPPSVSVSVEENNATGLITRADTHLEHKYGPFCQEDSMGDAKKQSRRSRGTSDEKL
LRCKCLEPIWVSRHHCLSCHTTFYTVEELENHNSGKCTSGSAVPEKRKGSEEPARGKIMK
KSEARQHLGMVTDRSQASKGADSALSRHIRFQNEGLLCPYKFDEISSKFVTNDSIKELVR
GIGLLGSEGMPSFVPSGSPYLSDPTLRIVFPKLDIAADVDQCQNPEESVPFTGKSRAGTV
VDSGSQRVLETKTDEDSEKGLPLPGIRHEKSKKSLARNFTVTDLYCTVPESSFKPVVGRA
AQILRQLKICLLDMEAALPEEALRQSKVHAEKRRAWHAFVKAAETIFEMVEATILLEDMI
KSEYLKNERWYWSSLSAAAKTSTMSSLALRIYALDNAILYERSVSDLISAGSLKPNTDVD
QQSPSNLDSSDKSKASNLDSSDKSKPSNLDSTDKSKPSNLDSSDKSKQGRRMSTRRRRDA
EG
>Sgl68425 DUB/USP 209.9 0.3
MADSQNDTNNGAPTLRVSVKWQKKVFPEVEIDTSQPPYVFKCQLFDLTGVPPERQKIMVK
GGLLKDDAEWPTAGVKEGQRLMMMGTADEIVKAPEEGTVFAEDLPEEEQVANVGHSAGLF
NLGNTCYMNSTIQCLHSVPELKSALLEYTQSQSGRNNELDQTSHLLTVATKDLFNELDKN
VKPVAPMQFWMVLRKKFPQFGQLHNGSFMQQDAEECWTQLLYTLSQSLKSPDTSESLSAV
KRLFGVELTSRVHCQESGEESTETESTFALKCHISHEVNHLHEGLKHGLKSELEKNSPAL
GRSAIYVKESRISGLPRYLTIQFVRFFWKRESNQKAKILRKVDYPLELDVYDLCSDELKK
KLEVPRQILRDEEGKKLGLKPSEKSSVSKDGDVKMLDAEGSSVGGGESSTGTSQEVEKEV
QFTGVYDLVSVLTHKGRSADSGHYVGWVKQDNGKWIEFDDDNPIPQREEDIVKLSGGGDW
HMAYICMYKARVAPI
>Sgl68459 DUB/USP 208.7 0.3
MGGFRERKRRRTTTAHDDVVKGKKTSKKRRRKVDGIYTSVSLMEVSEKHPNLVAEQKCLG
STVKECGKVIEYRAEKCKRPTNFTCRVESFGRMCSTFDEERKKWVMDMGFGGLLYLAGFQ
LPRTFVYWLFTRIDPMNEMFVDMDGVEHRLSANQVQWVLGLPRGRREVVVKCSNFVESRM
QLMKLEKAVGVNLSDRLARNPICWGSWPRVKVWSNDELRKVINEDKQKTGSDFGCIKMLN
VAYGESNPRDVRDCGVVGVEDDAEWPTAGVKEGQRLMMMGTADEIVKAPEEGTVFAEDLP
EEEQVANVGHSAGLFNLGNTCYMNSTIQCLHSVPELKSALLEYTQSQSGRNNELDQTSHL
LTVATKDLFNELDKNVKPVAPMQFWMVLRKKFPQFGQLHNGSFMQQDAEECWTQLLYTLS
QSLKSPDTSESLSAVKRLFGVELTSRVHCQESGEESTETESTFALKCHISHEVNHLHEGL
KHGLKSELEKNSPALGRSAIYVKESRISGLPRYLTIQFVRFFWKRESNQKAKILRKVDYP
LELDVYDLCSDELKKKLEVPRQILRDEEGKKLGLKPSEKSSVSKDGDVKMLDAEGSSVGG
GESSTGTSQEVEKEVQFTGVYDLVSVLTHKGRSADSGHYVGWVKQDNGKWIEFDDDNPIP
QREEDIVKLSGGGDWHMAYICMYKARVAPI
>Sgl68852 UBD/Alpha-Helix/UBA 27.4 0.0
MNKLRGNRDKVQQFMNITGVSEKVAQQALKAGDWHLEGALDIYYSQPQIKSLPDSRYLEE
LFNRYRDPNGDIINADGITNLCNDLQVDHEDIVMLVMSWHMKASAMCEYSKQEFIGGLQA
LGVDSLEKLRERIPYMRSELKDEQKFRDIYIFAFGWAKEKGQKSLALDTAIGMWQLLFAE
RQWPLIDQWCQFLQDRHNKAISRDTWAQLLEFVRTVDPQLSNYDAEGAWPYLIDEFVEYL
YENGIFQRG
>Sgl68926 E3_adaptor/Cullin_RING/DCX/DWD 144 14.3
MPGVAAASSSMEAVERQSLKKLTFKSLKRALDVFAPLHSHFPPPDSQSKKIRLDHKISLE
YGGIKPASVQPQSAKQIQGSASASSDNLALPAPEDALRGGAHNALVVAPAAQSKPSEVGP
SKSNAVISIPGSSDRYSTSALMERIPSRWPRPVWRAPWKNYRVISGHLGWVRSVAFDPSN
QWFCTGSADRTIKIWDVASGVLKLTLTGHIEQVRGLAVSNRHTYMFSAGDDKMVKCWDLE
QNKVIRSYHGHLSGVYCLALHPTLDILLTGGRDSVCRVWDIRSKTQIFALSGHENTVCSV
FTRPTDPQVVTGSHDSTIKFWDLRHGKTMSTLTHHKKSVRAMALHPKENMFASASADNIK
KFTLPKGEFMHNMLSQQKTIINAMAVNEDGVLATAGDNGSLWFWDWKSGHNFQQAQTIVQ
PGSLDSEAGIYALSYDVTGSRMITCEADKTIKMWKEDENATPETHPLNFKPPKDIRRF
>Sgl69066 E3_adaptor/Cullin_RING/BCR/BTB 47.4 0.0
MSVDESLRSVSLDYLNLLINGQAFSDVTFSVEGRLVHAHRCILAARSLFFRKFFCGGEQG
GGGVMGQACSPRSGGGQGQGQGQVIPVNSVGYEVFMLLLQFLYSGQVSIVPQKNEARPNC
GERGCWHTHCTSAVDLALDTLSAARSFGVEQLALFTQKQLANIVEKASIEDVMKVLIASR
KQDMQQLWTTCSHLVAKSGLPPEVLAKHLPIDVVAKIEELRLKSSIARRSSLIPHQHQHQ
ELGLESQEDHKIRRMRRALDSSDVELVKLMVMGEGLNLDEALALHYAVENCSREVVKALL
ELGAADVNYPAGPTGKTPLHIAAEMVSPDMVAVLLDHHADPNVRTMDGVTPLDILRTLTS
DFLFKGAVPGLAHIEPNKLRLCLELVQSAAMVISREEANNDQNTTPNNNTSNTSIYAPIS
NIGGDQEHTTSSTSSSGNVAPGNIGIGIDSRMVYLNLGAVGSTSMSDHHHHNEDNNHASH
RNPSSIYHHHQHQHQHHHHHEY
>Sgl69655 E3_adaptor/Cullin_RING/BCR/BTB 26.7 0.0
MMGGNQIVPKDTVTFNVGGKIFQTTSTTLANAGRNSFFGPLFDDDWNLHSSNSNSPPMSH
DQVMFIDRNPECFGVLLDLLRTGELYIPPHLPEKLVFREAEFYGVSDHVRGAKWGPFEGN
RLSLTRSVTGRAPGDGTAIRGGPDGGCCVAHGCIVHVYDWMMEERPPLNLDYQIVNDVGW
LDANHVVVSACERLGRGDGGMGVFNAANGELRHKFQVQHDNQPKTFTAGALAFTSESESK
MIYCSCKGRSNEYGVGVWDQETGQQVDFFYEPLGWSLGDADRLQWLPGSNCLLVSTLFPR
KDNCYISLLDFRAKSMVWSWSDIGHPNPNPNNPVLVDEKRVRDAIGMEDSSSICVVNEFE
DLGFIDLRSSASSVRWSSRSRLVNVMKANNRTSEDDEPCYPKLAFHNSQLFSSMNDSISV
FSGPDWVLTSRLRHPDGGPICDFSIAGDRLFALHSELNIFDVWEAPPSPHF
>Sgl69679 ULD/UDP/UBQ/UBQ_Other 31.8 0.0
MKMNKGKGPSLKRQSSTSGGASGGGAEEVTIDLTDQMLYLDIERTTGGRVKGSRSVLQKQ
KDACRSQPPVFTCRVETVGVVVSNFGDLEKQWVVDMGFGGLLYLQGKRLPRALCYWLMSR
FDPVTRTLFLSGSWAGSGCIELPINVGQVHWVFGLPHGDKKVPISKKFTERVKCLKEDLL
AEFGEQHQDGSRVVAMKNVVDRVEGNWRQEEELVFKTYFLILLLGDFIAPTTSARLSPDL
FTAVACVHNTNEYDWCSLLLDRLCEAGKKFAKNFYRDGFAKTCGGCTYFLAILYLDHLNI
QPKSWGMFPRLKAWSNDDINKVKLDDRFPSEDGKPRKGDFGKTPCFDGAYGEGHPRLGRD
SLGPHGGLDQVASAVVRAMGCQPDYEGMGACEKVGADALVDDGILPNPPRAKRRAPPVSS
NPYLRTLAKRKKEGGQAGLDFGSSQTKKMNDQCSELSPNKEDGRSKKSDENENVTFEHEA
LSESNATGGDNIHLNTDGGAVDVQPSQELAATTGGELGADESMKQVGNIVDELKKTMQEE
GEEISDSIIVSKVNELNKELQQREEEGQNTIHRSRSPEVEGEPLSRQSLESKDDANDCAS
VESKCSEAKNLTILQCGHMYASVPNCYTVLGTDGPGVDDNYIRAAAPLYTRMWKRTYVDR
SVRYMMDPMFAMRVDQERGLSSDTWESTTKRAASLSLPSRLWRRRCVRIVCSYRDLLGQS
RPQMDRWECPQLANKGSEDGGPRRRRSHINEEREWLLTDDLMNDLNEANALQKYATEKEV
EVDDLTLQLRRRFVHPDSTPAGNNMLHGDILTVMHKTGQLLSWDLLSDSRDYRLCTLQDL
CTEVFVTDMRVHLDDPVKVVRKQWEEITGVSWKNIMVYYEGKLIRAKTTFRDIGLKDGDA
IFMVGKTVFTKIGTV
>Sgl69707 E3_activity/RING/RING 34.3 15.9
MSSDNNNNNNNTTTSTSTFSFPQQSQQQQYFCYECNRTVSITPSSSSSELLCPNCNGGFL
EEVENPNPNPQPHPHSQFSSIFAPFLSPPPSSSSSAADQLAPFAPFFFPPSSASSSPLDP
VDLSSIFGAGNLNPNSNPNNPRSPFHDSDVFNPFQFLQSYLQTMRAGGANIQFVIENDQP
GAGSGGGGGGGNFRLPSNLGDYFFGPGLEQLIQQLAENDPNRYGTPPASKTAVEGLPSVK
VDQELLSSDSSQCAVCMDEFQLGAEAKQMPCKHVFHGDCILPWLELHNSCPVCRHELPTD
DPDYEQRSRGRRENPGSGGNGNGNGNGDGGMDEALQNEIVERRFRISLPWPFGGAAEGNN
ASGDGGNESNPRRRENPDFGSETRQEDLD
>Sgl70068 E3_adaptor/Cullin_RING/BCR/BTB 21.5 0.0
MKFMKLGSKPDAFQSDGSTIRYVSSDLATDVAIIVGEVKFYLHKFPLLSKSSRLQKLIVK
ADEEQSDEIELPGFPGGPKAFDICAKFCYGMTVTLNAYNVVASRCAAEYLEMNEDVDRGN
LIYKIEVFLNSSIFRTWKDSIIVLQTAKALLPWSEDLKIVGRCIDSIASKTSVDPTKITW
SYTNNRKLAMQDGIIEHQPTESVPRDWWVEDICELDINMYKRVMITIKSKGRMDGSVIGE
ALKIYAIRWLPDSIDALISDDHIQRNKSLVETIICLLPSDKSYGCSCSFLLKLLKVAVLV
DADDSARDDLVKKISTKLDQASVKDLLIPARPPQTTVYDVELVLCIVKRYVQQEKSCWEL
NLYENNEKGETELSLDRGSWVNVGGLVDAYLAEIASDPNLTPSSFIELSRSIPESARPIH
DGLYRAVDMYLKGHPDMTKAEKKQMCGLMDVKKFTMDASMHAAQNERLPLRLVVQVLYFE
QMRSATTTQSLTRTSNNTSSSTPNEEEEWDQRTLQSCKSVRKQMEKVKIEDNGELERNGK
MTIKDSSKNSRSGAQLLPSRSRRIFDKLWGIGKGNGESKSSETSGSSQSPTTSLVPGDTK
SSGSSSRNRRHSIS
>Sgl70117 E3_activity/RING/RING 36.2 5.6
MEAAMMQNKLTKLHSDQSDGNMPVDTSDDANCMLERGRMEYGCHHYRRRCRIRAPCCNEI
FDCRHCHNEAMNNIKLENTKRHDIPRHQVQQVICSLCGTEQEVRQVCINCGVCMGKYFCE
TCKLYDDDISKKQYHCEGCGICRIGGRENFFHCYKCGCCYSVVLKNSHPCVEGAMHHDCP
VCFEYLFESRNDVTVLPCGHTIHKNCLKEMQEHYQYACPLCSKSVCDMSKVWEKYDMEIA
ATPMPEPFQNKTVSILCNDCGSKSCVQYHIVAQKCPYCKSYNTRQLSG
>Sgl70139 E3_activity/RING/RING 33 9.1
MALRFAEYQGKNQTEKYPLLMDPERRNENEHVIDIRRSVEASSSGTTHDRISSELDSTQP
EDRPSSSARASISQLSLPLSNLSNSRNSSFSRRGNAHSRRRRSPLNSGLWISVELALTLA
QIVASVIVLSLSTHEHPRTPLFTWIVGYASGCVATLPLLYWRFLHRNQASDQDTSQSRQP
SSNGNPTQTVEDENNTTTFNRSMSGQSSGLHNARLKTAIEYFKMGLDCFFAIWFVVGNVW
IFGGHASSTEAPNLYRLCIVFLIFSCIGYAMPFILCATICCCLPCIISVLGFREDLNQTR
GATTESINSLPTYKFKLKKGRHSEGGGESGVVAAGTEKERVISGEDAVCCICLAKYANND
EVRELPCTHLFHKECVDKWLKINALCPLCKSEVGDTLLSSLAEATASLRRAENRVVSS
>Sgl70157 E3_activity/RING/U-box 104.4 0.1
MEVSLWRALLHNISSFFCLPSHENFDSATVQKSFLKMEEILKLLKPILDAVMDTEVASDE
LLNKVLEELGRSIDESRYLFEGWYPLASRVDLVLQAESLTVRIRDCVLEFFWILNDSRQS
LPMELSSSSLEHCIQKAKNIGCDTTSTIINDAVQHDQEGAHGPSPDRLVKIADCLGLRSN
QEILIEAVALEKLKENAEQAEKNAEVDHFEQLISLVMRMHDRLVMLKQSQSCTPIPIPAD
FCCPLSLELMTDPVIVSSGQTYERAFIRKWLDLGLTVCPKTRQSLVHTNLIPNYTVKALI
ANWCEINNVKLPDPMKCINEDQSIALLSHDDGSLRNSQINSHSKGNHVESPESMRSAGLE
GKTVSYSSDLHRERASPSHPRSSSDNSMFCMVEKEHGLDVGRVSLEERLSSSERKSVDLN
GQHHVPSARREYANGVSSHEQLSERNDGTSLDGNRDSEMNLAERLSGDADQISQSPGDSR
DASGELSNEPHASSLESTSRREPGFLPRLMDMKSRNQNIWRRPSDRLVARIISSPTTESR
PDLSETETEVKKLVDDLKSDSIETQREATAQLRLLAKHNMDNRVVIANCGAISLLVDLLR
STDPKTQENAVTALLNLSINDNNKTTIGNADAIEPLIHVLQTGTHEARENSAATLFSLSV
IEENKSKIGRSGAIGPLVELLGNGTPRGKKDAATALFNLSIYHENKARIMQAGAVRHLVE
LMDPAVGMVDKAVAVLANLATIPEGRAAIGQAGGIPVLVEVVELGSARGKENAAAALLQL
CTYSTRFCSMVLQEGAVPPLVALSQSGTPRAREKAQSLLSYFRSQRHANSRG
>Sgl70158 E3_adaptor/Cullin_RING/DCX/DWD 76.9 13.2
MAQTNWEADKMLDVYIHDYLVKRDLKATAQAFQTEGKVSSDPVAIDAPGGFLFEWWSVFW
DIFIARTNEKHSEVAASYIETHAIRARELQQQQPQQSQSQQPPNLQQQQLQMQQIFMQRH
AQQQQQQQQQQHQQQPQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHQHPPQPQRRD
GAHLLNGSANTNEVSGNDSLARQNCGTANSMATKMYEERLKSPLQRDSLDDAALKQRFAD
NVNQLMDQNHASILKSAAAGQPSGGQILHGTSGSMSQQMSSRNQQLPGSVVADIKTEANP
ILTPRAAGPEASLIGIPGSNQNGNNLTLKGWPLTGIDNLRSGLLQQQKSFMQASQPFHQL
QMLSPQHQQQLMLAQQNLTSTSANDVESRRLRMLLNSRGMGIGKEGLPNHVGDMVSNAGL
PMQAGCPVLPRGGDADMLLKLKMAQFQQQQQQQQNSNQLHQLQQNALSGQPSQVSNPSLH
QPEKIGGAASINMDGSLSNSFRGNDQAAKNQPGRKRKQPLSSSGPANSSGTANTAGPSPS
SAPSTPSTHTAGDVMSMPSFPHGGNSSKPALMFGADATGTLASPSNQLADMERFVEDGSL
DDNVESFLSHDDADPRDPVGRGMDLSKGFMFTEVNSARGSTAKVVCCHFSSDGKLLATGG
HDMKAVLWHADSLKPKATLEEHTKLITDVRFSPSMSRLATSSFDKSVRVWEVDNPSYSLR
NFTGHSATVMSLDFHPNKEDLICSCDGDGEIRYWSINNGSCTRVFKGGSTQIRFQPRQGR
YLAAAAENIISILDVETQACQHRLKGHSKQIHSVCWDSSGEYLASVSEDSVRVWSFGLGN
EGECVHELSCNGNKFYSCAFHPSYASLLVIGCYQSMELWNMSENKTMTLSAHDGLIAALS
VSSVTGLVASVSHDKFVKLWK
>Sgl70313 E3_adaptor/Cullin_RING/SCF/F-box 11.8 0.0
MDKPIWIDLPELPLEYHRMEILRLIGNALGTFIKADLSGEAKQSARFARVLCHVNAETQL
PEEIQIGGLSQRIARTEHVQRCTKCSKPWSLNHQCTKEKDEVPSTADAPNDDEGWTKVQG
RKQRGKMSVDGNFSIPGVHGNARVFTKQGKDTVSVDNVQISNFSYSAPSSQAHLSTVTDG
TFVESQSPAVLIHNPSHPPTHSTLNTKKGPDSSLTATLSSNPHPSLPKPSKIASAAATTP
TPSKQNDLSNQSLPSSGCQTLESQFDQTRTTTAPFLQGDCPPASSATAGTGASVLHKGRG
VPTHTESADVDTVRIQPQLDQDVQSSRKTANASGETSLLGTDGCDQENPERSKKCEISSE
RPKGSIAADGRGGSRSSSGSSTRHLGSRRLKRKTVHFSAVVPQRRSTEAPSRSHSPRGRS
TPVRPSARFESIAGNLAVELAVPKLDTSQLEQRPETGTNSVFLQASSDGKVIDIREMSDR
EWEARDRLQPQPDVPCFMTTLAWNVRGLARPSFMSNFLHLVTTHKPDMVILTETRVGPDN
TQAILRKLPFDQHVMIEPVGYSGGVLVLWNSSLIDFSVIKKETQSIHGFVKVLNSDFTFF
LSAVYGNPKHRLRKLLWHELCDFLPVVNNANWLVMGDFNQVTHSHEKFGGRMPSSSRMNE
FLSCIHHCNLLDVGYEGPKFTWSNKRRRGPIMERLDRALFSPSWLTAFPDAFLTHLPRIS
SDHAPILFRNTRPASSPLRGTPSFKFEPMWCMDPSFLPLIQNSWETTSGPFHQRMSALSS
NIQTWVKDIFGDLQKKKKELSARLLGVQKNLCLYPLSSYLQELEDSLSNELSTLLLQEEQ
FWHIRSRVNWLSEGDNNTGFFHKSVQVRRKTNRITALSSAVGELLTEPDQIQQHITSFYR
VLFSTERNEVEWPLQPISHLPVQSPPISVASVPTAAEIEEAVFQSNPLKSPGPDGFHSFF
YQKFWHVLSTDIVRFIQHTFYTTSIDPSINHTNVALIPKVQNPSSIKNFRPISLCNTVFK
FITKIILNRLKSLLPAMISPNQNAFLKNRGADTNFIVASEILHSMKTKKGSKGFFAFKID
LEKAYDRLEWDFIKTSLLSHNFDERSVNMIMSCIASTSTSILVNGSPTAPFLPSRGIRQG
DPMSPYIFILCMEWLSKLIEEECDKGNWKPFKFGQSGPRVSHLLFADDLILFGEADERTL
LSLTSTLDLFCHASGQLINSSKSTLVFSKNTDPFLIELFEAELNCSQTGSLGPYLGFPLK
DRKPTALDFNYLIDKTRNRLSQWKANFLSKAGRTCLIKSTLSSIPAYTMTCINLQQSVIQ
KMDSIACNFFWGKDGTKQGIHLVAWKDICTPKPLGGLGIKNLKGFNHISLVKLCWKLVTC
PTNLASEVIAAKYVFNRGNPYSFNKGSYIWKGLKEAWSDFTNNCRWVIGNGNNTSVWYDT
WASAIPLRTLFVGPLTLNHSLMTVSSLIQASQWNTDPLRPFHFLEDRLFRTIQSLPLPWS
DMQDRPVYLHLKQGKFWFRKAYEEWCTKSLTHDLVPQSIWSSFTIPKIKVFLWLASKNRL
PTRFNLFQRSITSSMFCPFCPNIAETAIHCLRDCPNALEIWEECGVDNTFFATSGHDWLD
QNLSNASAVQGLPWKIFFPFMCWSIWKKRNSWIFKLKNINKVECRKQACSSAWEFYSNLP
QPRPVNPLAQGTQRLLPSNLLHFINVDASWNSLTKVAGLGGSIRDDHLIWVGGFQATCLA
NSSLLSELFAIRWALSMIVQKEWTDVGVFSDCQVMVNLINDKAVVSHEYILLIVECRELL
AQSSGSLLQFIKRTHNMVADSLAKKAVDFCGALNTHRWLEDPLPGSTEALYQDMMFLSTM
INVNSNGNLRINIQQVMDPVETNCKLPEDLFRDILSRLSVRDLLRFRSVSKSWCALIDDP
SFILTHHFIQYTIHKANGDVPLLLWRHTGSIRGYQIECYLFFKQQGYDTFTNWTSDVERY
AHSVFPTNSDINLSIFCRGSANGIICLDFQGIDLKVKRRDFYYISLWNPATRDFKIVVYP
HVADQRMPGQFVVVGFGYDPVTNDYKIVATTVVTSDIVLAYMVYTLSTNSWKRVSEPSLF
GKTASVRCSLMDSCLNGVYYWTAHLLNNTEDKIFRILSFNFSTEAFIFSDPPQEALPPVY
LMGNEFYWNIGLYNERLALFLIHPALDTPEASADIWVATEFDDEFGVPVAWQCLISIKPI
FERIGSTFGAQWVDGDIVFELYPDEFSLYNPTTGKFRRLGISFRQCFSYVESLFPLSR
>Sgl70364 E3_adaptor/Cullin_RING/DCX/DWD 122.2 18.3
MKLAGLKSLDPAHEDSIWAATWVPATDTRPYALLLTGSLDETVRLWKADDDVVLERTNTG
HSLGVVSVAAHPSGVIAASASLDSFVRVFDVDTNNTIATLESPPSESWQMQFDPKGTMLA
VAGGSSTSIKVWDTATWKLVATLQIPRPESSKPSDKMATKKFVLSVAWSPDGRRLACGSM
DGTVSVFDVMRSKFLHHLEGHLMPVRSLVYSPSDPRVLFSGSDDAHIHMYDAEGKSMIGS
LSGHSSWVLSIDASPDGAAIASGSSDKTVKLWDLGMRAASQSMTNHTDMVWGVAFRPPGG
AGVRSGRLASVSDDKSISLYDYS
>Sgl70380 E3_activity/RING/RING 30.3 4.5
MTWAPTHHHHHVLEPASPPTATMTQGNYDPHVTKSMNVDSNMVVILGVLLFALLCALGLN
SVIRCALGCANQPHHHYNRREGLATYLGPGSRGLKRSTLQQIPTIIYHVANTTTSSSGGN
TVHNYSNNVMSTECMICLGEFIEGEKIKVLPKCKHGFHGKCIDTWLLSSSTCPTCRQSLL
ECAGSGAIVVPVAAVGESYGPHSS
>Sgl70390 E3_activity/RING/U-box 41.7 0.0
MASENLGLVPSQRMENNNLNSQLLFQNSNNPLRFGRGPENPGSKSGYVDDKLFSMDHRER
GYFSPELRRADDGVGGVYEEGPTSERRGRGDRDRTWNHREPASTPSSEEEEDDDEDDDDD
DDDEDDEEGKNSHSSSGVGGANSKDHAPFGSSTRKMMIKDGVILQPASDANRVSTSENEQ
QGRLGNFQKMVTVAEHDGDMYYLQLLHGTEGSSQGQKDLAVDNGSGLNGRKDSYVSSDPG
ESLRAIFSDPITGALMDDAMILPCGHSFGSVGVQQVIKMKACYTCSHSVAEDSVAPNLSL
RAAVQAFRREEDLQMYKASKRRRERFEQEKGNYGDSCFSDLPRGKGVQFPFSVTDRVIIK
GNKRTPPRFVGRQAIVTTQCLNGWYVVKTLDNAESVKLQYRSLEKVQNISSSTPISDKVI
PNWL
>Sgl70397 ULD/UDP/UBQ/UBQ_Other 32.3 0.0
MVGTLPILPLPAPPEDGNLGPTPLSQLPPDHDEKKEVEDQQKSGKPDSVATHALPIGIIH
PPLDISKIVDKTAQFVAKNGPDFEKRIIANNAGNVKFNFLNASDPYHAYYQYQLSELRSQ
NQSTVQQPSSQLDSEAEPVRMVLEPPEAEQYTVRPPEGISHEELDIIKLTAQFAARNGKW
FLTELNSREMNNPLFQFLKPTHSMFMFFTELIKAYSKVLMPPKGLTEKLKNSKADKTVVL
ERCLDRLEWEKSQEQARQKTEDERSQMAMIDWHDFVVVESIDFADDEDESLPRPMTLEEV
IRWSKITTKDDEEIIEPGKEVAMDMDEEDMQLVQEGMKAASLEENEKDKTNEVKADMDED
KDPMRIVKNWKRPEDRISAENDPTKFMISPITGELIPISEMSEHMRISLIDPKYKEQKER
MFTKIRETTLAHDDEISRNIVGLARTRPDIFGTIEEEVSNAVKAEIDKKKDEQPTQVIWD
GHIGSIGRTRIQAMSQSMGEEDEANNDGKPLPGPAAPPRSPVNMPHVPTSNVQYSAQNSA
GLMAPPPPRPMVGVNQMVPPPPSPMQLAPGQQHMMMIRQPMPPGSMNQSDMPVPPAPGTQ
FTPLGVHQHFTPVPPHGMLVGPPQLMSQGMPPPLSPPLEEAPHPLPKEPEPKKQKVDDSA
LIPEEQFLAQHPGPVRINISVPNIDGGNLKGQVLEITMSVNETVGSLKEKISGEIQLPSN
KQKLSGKAGFLKDNLKLAYYNVGDGEMLSLSLKERGGRKR
>Sgl70410 E3_activity/RING/RING 18.9 10.6
MARIKKKPRRSVGGFECGSTSKGNSGENSANPSCNVKSADDDHNNGNIEDTPYFVDVDRS
SWGSIEHKDLSEIVVNNLNFSSEFSGFDLTEELFVRIRLCNVNEYVSRMKLGHWPVIESE
NIYLEFLNKREIDGNKGFDVVVSGKFDGSDEGVTGLVHLVSLKYLTLRPVFGNRLSEGVS
SVRIRVEMLQSAFDACESVVSSSRPVWKKSMMSVMVWLRPEVATSEARYGVDMSSELELS
FYSDVDHSSYECSKFDICRFYEAIKRSKDCAMLDVELPDLLPELRPYQRRAAHWMVQREK
GASEDSAEESLYSSPLNVEVDFLDSHSKMFYNPFSGNVSMREEIPPYVFGGILADEMGLG
KTVELLACVFAHRKPSSEHDSCSRDISDGTEMEKTRPKRLKRERVECICGALSESSKYEG
LWVQCDVCDSWQHADCVGYLPPEDISRTTVGSTGQHNKNKRKKSAADIVMVNGEYVCPIC
SELMQATSSPIESGATLIICPAPILPQWHAEILRHTNPGSLKVFIYEGVKEVSLSKFSAM
DINELVSADIVLTTYDVLREDLSHDSERHEGDRRLLRYQKRYHVVPTHLTRVLWWRICLD
EAQMVETNVAAAAEMALRLHARFRWCITGTPIQRKLDDLFGLLRFLKASPFDVSRWWAEV
IREPYEKKDVTAMTFTHNLFRQLMWRSSKSHVADELELPSQEEHISWLSFSAVEEHFYQR
QHETCVNFAREVLHQIKSDIHERDCLGSFSSVSDPSTIHLEAEKLMNSLLKLRQACCHPQ
VGGSGLRSIQRSPMTMEEVLSVLIGKTKLEGEEALRKVISSLNGLAGIAILQGELFKAAS
LYKEALALAEENSDDFRVDPLLNLHIHHNLAEVLKSASNSSQQVSVCGGQLNRNPEEKPS
DIIGVIGCLDRIEKGQIGTGEDNSERAEDTDKHSEVNCNSSTNGSKGGIKCNIEPHAPHV
SSVESLIDISEGIKRKYLSGFYAKLSQAQQEFQKSYMQVCDSLNDEEVKHNVWWLEALHQ
IEQKKEVVHELSKRIENAVLERTKSPIIASGFRNMTALKFYIQNGLDLLDACRKKVLDQL
LNIDQTMENPNVEDIERVRYCSICDDSNTDGRLCVHCELDKLFQAYEGRLFLRRAKNGKV
ISSSVEVADLRKNTLENNQFYSKQKQNSNNLLSTSSADVVGKGKKGKMYMDSRVSSDLEI
ILGVIRSYFKPDLGEEGVSAANRHLSLFEIMKKEYTQARSLAIVQAQILRAHDETKMAMS
RLRLRDSDDDNSIDALSLEELDSANVINTSDKFVSLDSLSRIRGKLRYLQGLVISKNKIE
SDKEEAQESAVENANKLTAVNEDICPICQEVLQSQKMVFQCGHLICCNCLFKITDRKVGP
NGKLQNKWLVCPTCRQRSDYESIAFADDNHNRSSVGQSENLEASVFVQGSYGTKIEAITR
RILWIKSSDPEAKVLVFSSWNDVLDVLEHAFAANEISYVRMKGGRKNSQAAITSFKEDNV
TNQGIAKIKDQQNPESKFIQVLLLLTQHGANGLNLLEAKHVILVEPLLNPAAEAQAISRV
HRIGQTHKTHVHRFLVKDTVEESIYGMNRNKNSNSFVRNKKNRDQLILTVKDVESLFAVK
PKPSPPSAPDSNNEQNGDLMHLPPSAAAAIAAERRLGQC
>Sgl70436 E3_adaptor/Cullin_RING/DCX/DWD 38.4 2.8
MSSSVSTPQGFVPTSRFGAYEFTNPDPFGYDEPQKNDIDDAELLSVSWNQDYTCFAAGTS
RGFRIYNCDSFKETFRRDLKNGGFGIVEMLFRCNILALVGGGIDSQYSPNKVMIWDDHQG
RCVGEFSFRSEVRSVRLRRDRIVVVLEHKVYVYNFLDLKLLHQIETLANPRGLCCLSHQV
NTFVLACPGRRRGQVRVEHFGLHVTKIINAHESRLACFTLTLDGLILATASTKGTLIRVF
NTMDGTCLQEVRRGTEKADIYGIAFSQNVQWLAVSSDRGTIHLFSLRVRVVGEDESARPI
STPALMHQNSSSSLEPLIAQNTGANPSLSLPFVKGVLPKYFSSEWSFARFHLPQNTRCIV
AFGSHNTIIVVGLDGSFYRCSFDPSNGGEMSQLEYVRFLKTEGSPK
>Sgl70456 E3_adaptor/Cullin_RING/DCX/DWD 19.5 0.1
MEWSTIQHLDLRHVGREAKPLQPHAAAFHPTQALIAAAVGKYIIEFDALTGSKISTIDIG
SPAVRMAYSPTSGHVVIAILEDGTIRSCDFDAEQTCVLHSPERKMERISSDAEVHMALTP
LQPVVFFGFHKRMSVTVVGTVEGGRSPTKIKTDLKKPIVNLFCHPRLPVLYVAYAEGLIR
AYNIHTYAVLYTLQLDNTIKLLGAGAFAFHPTLEWLFVGDRRGTLLAWDVSTERPTMIGI
IQVGSQPITSVAWLPALRLVATLSKDGALQVWKTRVVLNPNRAPMQANFFEAAAIESLDI
PKILSQQGGEVAYPLPRVRALEVHTKLNMATLLFAKMASSDNVKNTGFTREGRKQLFAVL
QSARGSSASVLKEKLAALGSSGVLADHQLQAQLQEHHLKGQNQLTIADIARKAFLYSHFL
EGHAKSAPVARLPLITMLDTSNYLSDLPVCQPFHLELNFFSKANRVLHYPVRAFYMEGVN
LMAYNLCSGSDGIYKKLYNSIPGNVVCHPKSIVYSRKQNLFLVLFELGGAENEVVLYREN
TDTRLANSKDSTVKGQDAAFIGPEDNQFAILENDKTGLALYILPGKSSKELDEMNKAALE
ENPTADLAEDAAPNSVKGPVPFMFESEVDRIFSTPLESTLMFASHGNQISLAKLVQGYHL
SGSDGHGHYISTTAEGRKSIKLKVNEIVLQVHWQETLRGHVAGIMTTHRVIIASADLEIL
ASSSTKFDRGIPSFRSLMWIGPALLFSTATAISMLGWDGKVRTVLSTSMPNAVLVGALND
RLLLANLTDINPRQKKKIEIKSCLVGLLEPLLIGFGTMQQYFEQKLDLPETLYQITSRFD
SLRITPRSLDILARGTPVCGDLAVSLSQAGPQFTQVLRGSYAIKALRFSTALSVLKDEFL
RSRDYPRCPPTSHLFHRFRELGYACIKYGQFDSAKETFEVISDYESMLDLFICHLNPSAM
RRLAQKLEEDGADPELRRCCERILRIRSTGWTQGIFANFAAESVVPKGPEWGGGNWEIKT
PTNMKDIPQWELAAEVMPYMKTDDGPIPAIVTDHVGVYLGCIRGRGNVVEVREDSLVKAI
TSTGGDDKPNGTMTSFADSMMSKAAASADPKAASLMGLDTLTKQPSGSAAADEQAKAEEE
FKKSLYGTSGGDSSDDEEGVSKTKKIQIKIRDKPVSSATVDVNKIKEATRQFSLAPPMGR
TKSSAGGSQDFGLNFQPAVTATSTLPTTSNSGSSGDLFGSEALAQPPAVSQPSQAVKGGG
MTAAPIPEDFFQNTISSMQVAASLAPPGTVISKLDQNLQRAGSHPVETSKDNVGFADGGV
PPQATQLPATTTVESVGFPDGGIPPQSAGQTVVQPQVQTTQLQYSSQPLDLSVLGVPPGT
TDSEKPLAQSVPPSSVRPGQVPRGAAAPICFKTGLAHLELNQLPDALSCFDEAFLALAKD
NSRGADIKAQATICAQYKIAVTLLQEIGRLQRVQGPRAISAKDEMARLSRHLGSLPLLAK
HRISCIRTAIKRNMEVQNYAYSKQMLDLLFSKAPPGKQEELRSLIDLCVQRGLTNKSIDP
MEDPSQFCAATLSRLSTIGYDACDLCGAKFAALSAPGCIICGMGSIKRSDSLTGPVPSPF
G
>Sgl70502 E3_activity/RING/RING 29.1 14.6
MSTLIPPIPHESPTTNINISTTSGVGLGYGIAIAVSILVLISTIMLASYACVRFRSSSGP
RLRNSTVNNDEEAVNPNPTRPAVMIGLPGPVTIKLGRDTQPKNRVPYPEVVLGESKRLPK
PNTGPCSICLSEYKPKQIVRCMPDCNHCFHVSCIDQWLKMSPTCPLCRNSPAPSVGPTPS
GTPLMTEVVPLAFHPR
>Sgl70503 E3_activity/RING/RING 29.1 14.6
MSTLIPPIPHESPTTNINISTTSGVGLGYGIAIAVSILVLISTIMLASYACVRFRSSSGP
RLRNSTVNNDEEAVNPNPTRPAVMIGLPGPVTIKLGRDTQPKNRVPYPEVVLGESKRLPK
PNTGPCSICLSEYKPKQIVRCMPDCNHCFHVSCIDQWLKMSPTCPLCRNSPAPSVGPTPS
GTPLMTEVVPLAFHPR
>Sgl70535 E3_activity/RING/RING 27.2 9.7
MKVPCCSVCHTRYNDEERAPLLLHCGHGFCKECLSRMFSSSLNNSLSCPRCRHVTLVGNS
VSALRKNFALLAVTATGNSSSDDDVSDGDGDVDNDEFEEFEEDRRRSSSASSSGGCSVGG
VIELANHGELKFLQRIGEGKRSGVEMWAATLAGGVRCRGRCRHKVAVRKVAITEEMDVMW
VQTQLEGLRQGAMWCRNVCTFHGVSRGVDNYLCLVMDRCYGSLQSAMLRNEGRLTLEQIL
RYGADIARGVAELHAAGVVCMNLKPSNILLDAAGHAVVSDYGLPSILKKPICRKARAEGD
SSIIHSCMDCTMLSPHYTAPEAWEPVRKSLNLFWEEAIGISAESDAWSFGCTLVEMCTGT
IPWAGLSAEEIYRTVVKARRLPPQYASVVGVGIPRELWKMIGECLQFKPSKRPTFSAMLA
IFLRHLQALPRSPPASPDNDLEACASTNLIEPSPTSVLEVYPYNPNQLHRLVSEGDLNGV
RNFLSKAASGAGSNAVSSLLEAQNNDGQTALHLGCRRGSVELVQAILEYKEADVDILDKD
GDPPLVFALAAGSPECVRALIDRNANVRSRLREGSGPSVAHVCAYHGQPDCMRELLLAGA
DPNAVDDEGESVLHRAVAKKYTDCALIILEHGGSRSMGVRNLKNMTPLHLCVATWNVAVV
RRWVEVASIEEIAVAINILSPVGTALCMAAAAKKDHEKEGRELVRLLLTAGADPTAQDAQ
QRTALHTAAMADDLELMQIILDAGVDVNILNVHNTIPLHVALARGANSCIGLLLSAGADY
NFQDDEGDNAFHIAADAAKMIRENLQWIIHMLKYPDAAVDLRTHSGKTLKDFLEVLPREW
ISEDLMEALLDKGVQLSPTIYDVGDWVKFRRSITAPKYGWQGAKQKSVGFVQSIPDKDHL
VISFCTGEARVVVNEVIKVIPLDRGQHVKLKEDVKEPRFGWRGHSRDSVGTVLCVDDDGI
LRVGFPGASRGWKADPAEMERVEEYKVGDWVRIRPSLTTAKHGLGAVTPGSIGVVYCIRP
DSSLFLDLSYLPNPWHCEPEEVEHVEPFRIGDRVCVKRSVAEPRYAWGGETHHSVGRISE
VESDGLLIIEIPNRPIPWQADAADMEKVEDFKVRDWVRVKASVSSPKYGWEDVNKNSIGI
INSLEEDGDMGVAFCFRSKLFCCSVTDMEKVAPFEVGQEIHVMQSISAPRLGWSDESPAT
VGKIVRIDMDGTLNVKVTGRSSLWRVSPGDAACLSGFEVGDWVRSKPILGTRPSYDWSSI
GKEGVAVVHSVQENGYLELACCFRKGKWHAHDTDMEKIPNLKVGQYIKFRAGLAEPRWGW
RGANPNSRGIITSVHADGEVRVAFFGLLGLWRGDPADLEVEAVFEVGEWVRLKDGAGNWK
SIGPGSIGVVQGLGYDSDEWDGTVSVGFCGEQEKWTGPISHLVKADKLVLGQKVRVKLSI
KQPRFGWSGHSHGSIGTITTIDADGKLRIYTPAGSKAWMLDPSEIEVVEEEEIYIGDWVK
VKESVTIPTHQWGEVNPSSIGVVHRMEDGQLWVAFCFMERHWLCKASEMEKIRAFRVGDK
VKIREGLVAPRWGWGMETHASKGEVVGVDANGKLRIKFRWREGKPWIGDPADIALDET
>Sgl70567 UBD/UBC-like/UBD_UBC 102.3 0.0
MSTSNSYLLFEQKPTKRRPTRRRTPLRPPSSSIDDRGKMINLFKVKAKQRENAENLNGKA
PGKKQTAGELRLHKDISELNLPKSCTISFPNGKDDLMNFEVVIRPDEGYYLGGTFVFSFH
VPSVYPHDPPKVKCKTKVYHPNIDLEGNVCLNILREDWKPVLNVNTVIYGLYHLFTQPNY
EDPLNHDAAAVLRDNPKMFENHVKRAMSGGYVGQTYFSRCIS
>Sgl70570 E3_activity/RING/RING 10.2 7.2
MEEQISSSIPRDHKLCGFLTTVLSSSLNSEFKTLEFGTILEFSSTGSNVVFKSDSGVVLS
PINLPNLKPNSTAKKRSNKKKKEFVYVTPKKRRRKEVDVEVKSLNSNSNAKKLGIGHGNG
TVSVVQQVKILVNQKCLKIVARVVGVSKAEDGEVRAAVLVDVYLPNDVWESGWQFPRSAT
TAASLFRHLRCDWGERTSILNNSHNKDVGDSKVLWNLADCHVIGCKLHSDIADSSEIKGY
ELHEIFKSLPSLNGDLKTYSSRISPKDMTSVSGIWDVTDDIVVNILSKLGPIDLVRVSAT
CRHLRLLSISVMPCVKLKLFPHQQAAVEWMLQRERKVSTLPHPLYLDFYTDDGLAFYLNI
VSGELITGSAPTFKDFRGGMFCDEPGLGKTVTALSLILKTLGTLADPPEDAEIHWCSHKA
DQKYGYYECSGIRCTDLAVPSLSQRCVSQNDRRGQFSPDDLIPMDQSTPKNTRLQAYCGE
TASSSCPERLDSASSLLSPSTTMATVVRCKRRLNHVKRNLLHQYKSHCSDSVSSDDDWTG
SYSGKRKYTSNNRSNVALNKQKSYRGKRRRKVSEDQYVVSDETWIQCDACKKWRRLLDGS
LADSTADWFCSLNSDAEYQSCNAPEESWDCREPVTYYRGFCSEESPGGLPQNVAFFTSVL
KEHYSLLNFHTKKELTRFARFSQNQLLEMKRVGLAHAGQVATKGAIGFHKIFEAFGFVKR
LEHGVGRWFYPKTLDNLVFDLPALRIALCKPLDSFNMYLSRATLVVVPSNLVDHWKSQIQ
KHVRPEQLRLFVWTDGKKKKPSVHNLAWDYDVVITTFERLSAEWKPPKRSVLMQVHWMRV
MLDEGHTLGSSVTMTNKMQMAVSLSASNRWILTGTPTPNTPSSQVSHIQPMLKFLHDEVY
GKSHKNWEAGILKPLEAQMEEGKSRLLQLLERCMISARKADLRCIPPCIKKTTCIDFTEE
HAKTYNELVVTVRRNILMADWNDSSHIESLLNPKQWKFRYSTILNVRLSCCVAGHIKVSE
VGQEINEAMDILVQNGLDPLSEEHALLRYYLKYGGNCQRCNEWCRLPIVTPCRHVLCLDC
VALDSEKCVFPGCCYMYEMQNPEIRTRPENPNPKWAVPKDLIELQPSYKQDNWNPDWEST
SSSKVAYLVQRLKEIQVASRERVCSMRKYAERPYGIVLSHGTCYLQNVDSSETPVEKVLV
FSQFLEHIHVIEQQLAFADIRFAASYIPMIPKDKKKALANFHEDPSCMVLVMDGSAALGL
DLSFVSHVFLMEPIWDRSMEEQVISRAHRMGAVRPIHVETLVMRGTIEEQMVEFLQNGDA
CRRLLKEDRDKTDHEGARTYKSLHDFAERTYLVRLSMVRTKASSP
>Sgl70574 E3_adaptor/Cullin_RING/DCX/DWD 115.7 26.4
MEDLHTNLKGELADDLGNFVNRVLTFVTKPPWLTYLSFMPYIKYEGNRHFLYRQVSLVLS
ILNIERFQRPWEIKWGSQSNNDVYKLESEYCESQKDXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXSHADNFAAKRMRKLTQRRAVDYTSTVVRYTQVRMWQRDARDRTTLQPTPG
AAVDLLPPAAYSDNPSTSFAAKFVHTSLNKNRCSINRVLWTPNGRRLITGSQSGEFTLWN
GQSFNFEMILQAHEQAVRSMVWSHNENWMVTGDDGGSIKYWQNNMNNVKANKVAHKESIR
DLSFCRTDLKFCSCSDDTTVKVWDFARCQEEKSLTGHGWDVKSVDWHPTKSLLVSGGKDN
LVKLWDTKSGKELCSFHGHKNTVLCVKWNDNGNWVLTASKDQIIKLYDIRAMKELESFRG
HRKDVTALAWHPFHEEYFVSGSFDGSIFHWLVGHETPQIEVLNAHDNAVWDLAWHPVGYI
LCSGSNDHTTKFWCRNRPGDTGRDKINVGYNQGYSEQNPAFANRAPGNFPMPEPPTTPGS
LPPGLSRNEGTIPGVGAAMPLSMDSSQGEQMQAHPSSMPMGAPPLPPGPHPSMLTSNQPQ
GYQHNSQQIPQQGHPQQMPSFPQPPPNMPQLQPQSHMPMHHHMHRPPPQMPPHNMPSNIP
SSMPGSMPMPPASVPMSMPGPMGMQNVTNQMGQQMQQGHFMGMNPMQSGPPSGGMPPPGG
GFSNGMPNMQGPPTTSGPQMYPPAGAFNRPQGGQMPMMPGLGPYQPSNQSGLPPPPLPPG
PPPPQTQQ
>Sgl70590 E3_adaptor/Cullin_RING/SCF/F-box 13.7 0.0
MASIAEEEHLNPFSKVISMSKMEDNHKWRRLSKCSSTTFDSPINTLDDGCLMHILSFLSP
IPDRYNTALVCHRWHFLACHPRLWLRVDRTIKDSSEPNVFSSVDAAVSAAKAGDTILIAA
GGVHITSNIQIKKPLCLIGGGDLPEETTLICSRGSDSALEFLSTCKITNLTVKAELGCCL
LHRSGRLIIDSCVLQCETDPLDYLSCPIVSTASGPKKLPSSLSPMSLGDGVTVSRTQIEG
GAKAVMTIGTLVLQRVRVIYGRSSVLFWFEVEHQ
>Sgl70653 E3_adaptor/Cullin_RING/DCX/DWD 85.6 18.2
MCSILLNPKRSLSTPLLYQSSSATSESGSSTSSNEEAGPSFYSSRFNIKDVVNTKSILGG
SKSYKLLDILSGHVGPISCLSLCGEFVLSASQGKDIIVWQQPDLKVFTKFGAGEGSVKSV
VTVGNKVFTAHQDSRIRVWKVSRRSENVFRLVDTLPTTKDYLGRFMRQSNYVQVRRHHKK
LWIEHADSISCLAVENGLIYSGSWDKTLKVWRLSDLRCLESVQAHDDAINGLVARKGVVY
SASSDGKIKVWGKDQGVKSSSLNCSSSSLLHKSIGVLEGHKDVSMNAVIVSDEFGIGNER
VYGGASDGYLMGWERKGGDGDGDGGEWKVVVEVKAHELSILCLNFMGDILCSGSADKSIG
LWKREVLNNGLRGELCKVGVIRGHEGPIKCLQSSLNCVGGGYMLYSGSFDKSIRVWWVSK
DINDFEDQKSPVNFLEGCF
>Sgl70719 E3_adaptor/Cullin_RING/DCX/DWD 71.9 10.3
MAEISASENDSSSSNSTSITDLDVDSLANCANFLSIQDISNMAITCKYFRYAAYSDSIWQ
RLFREKWPENMLGQKPPGSVVREAYLSRRAAVQRFGFVDPLVVDFYTDARPFNHVLLGKN
DIIFSQGSLIQHLKIEDFVKGKECLVSLRDHNARITCMRLFPVKEATFIRCETQNDDNVL
ITSSSDHSIRLWWKGSCLRSFRGHNGPVSALSDKLLGNMGNRVLASGGEDGTVRLWSLSS
SGKRGQHALNATLHGHEKPIKYISAAGHKISLLISVSTDSKIRVWDSSASSRKSSCVGST
SVLGTPVGIKCFDSMLYVAAGYSVQAIDLRTMKTAFTAAVCPPEIYTFDMLASRSLICTG
GKDKALLWDVRKSKPVAEMEGHNGSVTQVHVDPYKIVTGSPEDFFTKVWDVETGVFINSL
NCCPSELSSSRMGCNAMAVDGCRVVTACCGDNGLLRFRDFNNASCSISSYQDAVSSGFWN
SSSYSDSDSDV
>Sgl70807 E3_adaptor/Cullin_RING/BCR/BTB 20.4 0.0
MACIRIGSKSDSLRREGQAWFCESGLASDVTIEIGESSFQLHKFPLISRSGLLEKRIGEI
SSEDGSICIVKLDDVPGGSNAFELVAKFCYGIKLEINSSNVVSLRCAAEYLQMTEDYGEG
NLIAQTEAFFSEIFSSWTDSKEALESCEDVLQQAEDVHVVTRCINSLAMKACSDPSLFGW
PVCGQSKSSKDNKSLWNGISSGDKAEINASATANTADDWWYEDVSSLTFSLYKRLIKAVE
VRGMQPERVSGSIMVYARKNITLLNNQPTSQAQKDAVVPESEDLTTLYEDAQRNLLEEII
NLLPPQKGVTPTKFLLRLLKTSMNLHCNPDCLEILEKRIGAQLDQAALVDLLIPNTGYAS
ETLYDIDCVQRIVDYFMQMQSGVGVSGTSSPAIGEDSGQLGNPTQSIASMTLVAELVDSY
LAEVAPDVNVKPPKFQSLAAVIPDYARPKYDGFYHAVDIYLKAHPWLTESEREQICRLMN
CQKLSVEASTHAAQNERLPLRMVVQVLFFEQLRLRTQISGWFFLSDNLDNSQAREQDEIV
DQDRALVVTGDVRTRVSELEKEYQSMKQEIQKLTKTKKRWSIFARIFARPKPRGPPGQLM
QPKSGHSKVQQSAALLRKHQLENAKHAELDHTKNQN
>Sgl70817 E3_activity/RING/U-box 74.8 0.1
MATQKPQRSPEEVEDIILRKIFLVSLIDPMELNSNSSAVYLELTAAEIMSEGKELRLCRD
VMERVLIDRLSNEFPNAEPPFPYLLGCYRRACEENKKILNMKDKNLRSEMELVIKQAKKL
AVSYSRIHLGNPDMFPGVDDANVNANSMGKKPSPLLPLIYSEAGGALIDSYGGGSSGGGI
TCPPGLLDEFFKEGDFDSLDPIFKTLYDNLREKVVRESALGDFQQPLRALLYLLSIPAGA
KSLVTHKWWMPPGSFLNGRAMEVASILGPFFHISALPDTALFKSQPDVGQQCFSESSSRR
PADLLSSFTTIKTVMNNLYDGLHEALLCLLKKSETRENVLEFLAAVINSNSSRSHLQIDP
LTCASSGMFVNLSAVMLMLCEPFLDANLTKRDKIDPSYVFYSKRLDLSGLTALHASSEEV
SSYISELKNGRADGSTDNSAKNNRLLTSFEATGSGSNSGGPPVQSVTPVSNSGDKVKYNF
ICECFFMTARVLNLGLLKAFSDFKHLVQDISRSEDSLASLKAMHEQTPTRQLELDIARLE
KEIESYSQEKLCYEAQIIRDGGLIQRALSFCRLMVVWLVGLVGGFKLPLPAPCPMEFACM
PEHFVEDAMELLIFSSRIPKALDGVLLDDFMNFIIMFMASPEYIRNPYLRSKMVEVLNCW
MPRRSGSSATASLFEGNQLSLQYLVRNLLKLYVDIEFTGSHTQFYDKFNIRHYIAELLEY
LWQVPSHRNVWRQIAKEEEKGVYLNFLNFLINDSIYLLDESLNKILELKTLEAEMSNTAE
WERRPAQERQERTRQFQSQENIIRIDMKLANEDVSLLAFTSEQITSPFLLPEMVERVASM
LNYFLLQLVGPQRKSLSLKDPEKYEFRPKHLLKQIVNIYVHLARGDEGNVFPAAISRDGR
SYNEQLFSAAADVLIRIGEDGRIIQEFVELGAKAKFAAVEAMDAENALGDIPDEFLDPIQ
YTLMKDPVILPSSRVTLDRPVILRHLLSDSTDPFNRSPLSPDMLIPDHELKAKIDEFIRS
QATGNQGDGIPLQSTKVTLPNPTTDVQLID
>Sgl70858 E3_adaptor/Cullin_RING/SCF/F-box 16.5 0.0
MAGNKRRRIKSLSAAIRDDNTCVDKLHKHTQFLPSWSDLPPELLELILSHLTLRENIRFS
AVCKSWNSVAVSVRLVNQPPWIMYFPKFGDLYEFYDPLTRNTYSIELPELCGSRVCYTKA
GWLLFYRPRTHRLFFFNPFSRHLIKLPRFEITCQIVAFSCVPTSPTCVVFTVKHVSPTVV
AISTCHPGATEWITANYQNRLPFVSSIWNKLVFSDGQFYCLSLTGWLGVFDPKELTWNVL
VVPPPRCPENFFTKNWWKGKFLAEHDGDILVIYTCCNDYPIIFKLDQANMVWDEVKTLDG
ITLFASFLSSHSRTDLPGTMRNSVYFSKVRFYDTTLASNSMTGESRIRLRAYGLNRPRTY
LFSCDASPIL
>Sgl70868 ULD/UDP/UBQ/UBQ_PIM 101.4 0.4
MQIFVKTLTGKTVTLEVESSDTVNNVKAKIQDKEGIPPDQQRLIFAGKQLEDDRTLADYN
IQKESTIHLVLRLRGGGSGTLSYPPTLLALARQYNQNKLICRKCYARLPFRSTNCRKKKC
GHSNQLRPKKMLQASGLGR
>Sgl70878 ULD/UDP/UBQ/UBQ_PIM 101.4 0.4
MQIFVKTLTGKTVTLEVESSDTVNNVKAKIQDKEGIPPDQQRLIFAGKQLEDDRTLADYN
IQKESTIHLVLRLRGGGSGTLSYPPTLLALARQYNQNKLICRKCYARLPFRSTNCRKKKC
GHSNQLRPKKMLQASGLGR
>Sgl70915 E3_adaptor/Cullin_RING/SCF/F-box 13 0.0
MCDWSMLPSDILGEIALKLDQLEDFVYFSAVCHSWNYASSLIKPNWNFDKVTPWLLLAEP
EKTSENPNNNLC
>Sgl70949 E3_adaptor/Cullin_RING/SCF/F-box 12.7 0.0
MVSKRQRRKEGSVDKISSLKSEILTRITSFLSPRDAARTCVLSKKWKYIYKGGKRNAKVA
KVAKVAKVAKVAKVAKVAEENKWLDPPVFFFVNVLRFSDLRTTIPQLRGVCKSWRSCVDG
QELFPVPKISVPASFPVKSIMKCLPQISSNILFHKSNDRTCFYMHQHHYYLLSHNSHGPQ
APWIIRVHETDANKWRLLDFSRIGMELFKAKPKLCARINLLDCGIEQLHCSWNVVVREGS
KKRCISKKVVGGWDLEASNYKFSVLIELNISKKLILLRMDKQGKFKVNKLFQDKSCNIIE
IAYHKGQFYVFDSKNWKVGFIDPQQPIIQIEFFSAPGQAPETTAIDFHAHMLSCDNNLFL
VIDVVLERQKKSLTAFVLKQLNWTRLDSLEDTIFFIGTSFCFGLPLASEKLPNWRPNLMC
FLNKRGAFRTSMLNMPVGIDFKYKDYKESLKLYELSDSKKAAIDVSSDWKKYTGIFFPPP
SWVLWHIVGGYIGYTVKLNELGFK
>Sgl70963 E3_adaptor/Cullin_RING/SCF/F-box 17 0.0
MLSLRTKNLTMDNNNDTQNHLPEELLFYEIFLCLPIKSLLICNCVCKKWNSIISNPEFAS
LHLKKSPFSNDQSLLINTKTGFLSFDLENFGVEAITETTADSVVASCNGLVCLDDEATNS
LYIWNPITSKKIRIPYPQPLVTTQVVWGLGYVSSTEDYKLIRIYNENFDQKVQIFSFHNN
TWKNSDIECEMCSFEELPPINGSGVSVNGMIYWATYYTEYDVGFYDHCFNILGFDVMKEK
FMPLTPVPEWSDRGFEQNSVLFLSNGCLCACWRTDEGDIDIGMLREEEAGKQSWVKHFHF
DHGSLLYDRKISFQKIQGVTKAGKYAVHVDGEHIILLDSNQDSSKEVQLKIPRARNVIGY
LKSLLSPSNMVNYKN
>Sgl70965 E3_adaptor/Cullin_RING/SCF/F-box 13.5 1.0
MENFSANLDDGELWIPSDIFPKDELHHHDCHNNRSIRDDDSLLEDLSRQLCNLKSNDLFL
TPNVSHLSKEFGGYSGAMTQNSSATTLAPAPAPAPTPTQNGCSDLKVGPKRVDDRGRPIN
NQPGPVHRLPALPFPMPQPTNPTVGQPLKETKTGNKSRKGYRHQQKHNWVFPTQQGRRGV
GFRFGLMNSNNASSGTGVFIPRPNSDSFETTEVKPQWMPTTKVGTKKDDDEFRHNTPPEV
GLPKDWTY
>Sgl70996 E3_adaptor/Cullin_RING/SCF/F-box 12.5 0.0
MKKQRTTMAETPSSSSSLSLASANVFDLLSEEIVFIILDYLHDNNPQDRKAFSLVCKSFY
SIESKHRRTVKPLRAEHLPAVLNRYPQISTLDLTLCPRITDFSLSIIASNCAKTLRSIDL
SRCKFFTGSGLEILVASCRNLVALDLTNATELRDSAAAAIGEAKNLEKLWLGRCKLITDI
GIGCIAVGCPKLKLIGLKWCLGIGDLGVELVAVKCKDLLSLDLSYLPGLMTFVAYAFCGI
TSKCLPAILKLQYLEELILEGCFGIDDDSLTLLKQGSKSLKTLDMSSCQNVSDTGLSLLT
SGTGCLRQLTLAYGSPVTLDLARSLQRLSKLQSIKLDGCLVTCSGLQAIGNYCASLRELS
LSKCSGVTDDGLSSLVKKQKDLRKLDITCCRKLTCVSIAHIAYSCTSLTSLRMESCTLVP
REAFVLIGRKCHQLEELDLTDNEIDDEGLKYISKCSRLSILKLGICLNITDVGLSHIGNR
CSKLVELDLYRSMEITDSGITAIARGCPGLEMLNISYCNSITDASLISSSKCARLNTLEC
RGCPLITSLGIAAIAVGCKHLTMLDIKKCYNINDFGVLPLAHFSQNLKEINMSCTSITDV
GLLSLASISCLQSMIILHLKGLTPRGLAAALLACGGLTKVKLHSSFKTLLPRPLFEHLEA
RGCVFQWREKMFQDELEDSKSWKMQVAELNNDS
>Sgl71006 E3_adaptor/Cullin_RING/SCF/F-box 13.7 0.0
MQRVRISSKHSPVFKLGDSQLSLSPKFRVAAIKSHLDDPSSDLELAIKGQPLIPGLPDDV
ALNCLLRLPVQSHGACRAVCKRWHLLLGSKERFFTRRKELGLYDPWLFVLTFHKCTGKMQ
WLVLDLTHFTWHTIPEMPCRDKVCPHGFRCVSVPNEGTLFVCGGMVSDVDCSLDVVLKYE
IHKNRWTVMNQMITARSFFASGVIDGMVYVAGGNSADLYELDAAEVLEPSKGCWRPIASM
GTNMASYDAAVLDGKLLVTEGWLWPFFVSPRGQIYDPRTNHWENMAVGLREGWTGSSVVV
FDCLFIVSEHERMKLKVYDLNSDSWEAVEGQPLPEQICKPFSVNSWDSSIYVIGRDLYVA
VGQISKVILEGHSEKKLRFSVRWHVEDAPMAFSDLTPSSSQVLFA
>Sgl71025 E3_adaptor/Cullin_RING/DCX/DWD 52 0.0
MALGDLMATRFAHSTVVVSNHLDEYISRDDAELYRDGDRDLPETASTSGGGNGYENAIIV
SSAAAAGGNTSTTTTTAISMMYFPQTIVFCELRHEAFEDSVPTGPAESGLVSKWRPRDRM
KTGMVALVLCLNISCDPPDVIKISPCARRECWIDPLSMPPQKALEAIGKALSLQYERWQP
KARYKCQLDPTVEEVKRLCNTCRRFAKAERVLYHYNGHGVPKPTTNGEIWLFNRSYTQYI
PLPITELDSWLKSPSIYVFDCSAAGNIVNAFIELIDASAASGATKDCILLAACEAHETLP
QSAEFPADVFTSCLTTPIQMALRWFCKRSLLRESLNHSLIDKIPGRPNDRKTLLGELNWI
FTAVTDTIAWNVLPHDLFQRLFRQDLLVASLFRNFLLAERIMRSANCSPISYPMLPPTHQ
HHMWDAWDMAAEICLSQLPSLIDDPTAEFQPSPFFTEQLTAFEVWLDHGSEQKKPPEQLP
IVLQVLLSQCHRFRALVLLGRFLDMGPWAVDLALSVGIFPYVLKLLQTMTPELRQILVFI
WTKILALDKSCQVDLVKDEGHTYFIRFLDSSEAYPEQRAMAAFVLAVIVDGHKRGQEACI
EAGLLDVCLKHLQASTPNDSQSEPLFLQWLCLCLGKMWEDFPDAQIVGLQAGAAVISASL
LSEPQPEVRASAVFALGTLLGVGFDSSGDAGEEESDDYEISILKSLLNVVSDGSPLVRAE
VAVALARFAFGHNRHLKSVAATYWRSQPNSGFSALHVNSTGSGYNTPNNYMSPGSIVTSQ
MGLLRVGGDNTPIVRDGRVSTSSPLATTGIMHGSPLSDDSSQHSDSGASNDAVGNGIMNH
ARPRPLDNSLYLDCVFSMCALAKDPSPRIARLGRRVLSIIGIEQVVARPIRPSTSSTRPG
EPSTSAGVRLAGLARSSSWFDMSSGHIPLTFRTPPVSPPRASYLTGIRRVSSLEFRPHVL
SSPDSGLADPLLGYGGSSGQNERSLLPRSTIYNWSCGHFSKPLLTASDDSDELIVKREAK
ERSARDLITKCQHYSVTKLNNQIASWDTRFETGTKTTLLQPFSPVVVAADEKERIRVWNY
EEPTLLNSFDNHEFPDKGISKLCLLNELDDSLLLVASGDGNIRIWKDYMQKGKQKLVTAF
SSLPGHGPNARNVNAVVDWQQQSGYLFVSGEVRSIKVWDLDKEQLVHDVPSSPDSNISAL
AASQVHGGQFAAGFADGSVRLFDIRTPEMLVCATRPHIQRIERVVGIGFQPGLDAPKIVS
ASQAGDIQFLDIRNHRDAYLTIDAHRGSLTALAVHRHAPIIASGSAKQLIKVFNLDGEQL
GTIRYHPTFMAQKIGPVSCLAFHPYQVLVAAGAADPFVTLYADDNNPAR
>Sgl71050 E3_activity/RING/U-box 106.8 0.1
MVSSPTIFPQRRRRPPPTSFLPPQLSTVDLLSSLYCLSSEISSLHPPQHLFKRNSSSIIR
KCRILSVIFEEIYRHKSSINPSNPSSLLCFEEMFIVLQRIRALIEDCFNGGSKLLLLMQI
EPISSTFHELTLDLWTLLEILPKKELNLTEDVDELRNLVIKQCCNDKSFVDPSDNRLRIE
VLKLLDSIKKEIVPNQSKLSEILSKLGITDSASCREEIEWLEDEIQCQNDEKSKSEVISL
IGLVKYAKCVLFGASSSSGSSNNFSDESFRRNSLSEMNIPTDFRCPITLDLMIDPVVVAT
GQTYDRGSIVLWMESGHNTCPKTGQTLAHTSLVPNKALKSLIAMWCRQHRIPYAAAEGSE
GRNRGVALNKAALEATKMTVSFLLGKLGGSPQPVEMVNRVIYELRVFAKTDSDSRACIGE
AGAIPLLVRYLGPEHPKLQVNAVTTLLNLSILESNKVKIMETDGALNGVIEVLRSGVTWE
AKANAAATMFSLCGVSAYRRRLGKKTRVIKGLLELAREGPTSSKKDALVAILTLAGDRET
AGRLVEGGVIDMVKEVMEELPEEAMTILETVVKKGGFIAIAGVSHMLGRLVAMLRTGTDR
AKESVIATLVLICRKGGAELVSELARITTIEVVIWELMGTGTARAKRKAASLMRILRRWA
AGLDGRLVEAFSVTMALE
>Sgl71090 E3_activity/RING/RING 35.5 6.5
MNMQRKLLYTAVAAPATASDNNNNRTSSMDSQLTQANFDTNMVIILAALLCALICALGLN
SMVRCFLRCGQRFGMESADHAAARMSSTGLKKSALRKIPVAVYTAEDSKTGGKSDTSTDP
SEDVECPICLGEFIDGEKVRVLPKCNHRFHVSCIDTWLGSHSSCPNCRLSLLEVCTSSTT
KAADGEVGASEEPPWGGERQDHVVVEVSGGS
>Sgl71153 E3_adaptor/Cullin_RING/DCX/DWD 108.6 22.5
MAKLETCSAGELGSGISNHDEEEKDVFLDDSDIIEEFLLDDEDLPDADADADADADADDN
ESDNEAVSEGMSETDDAIDIFAHGTDPMYAVACNPKDATLVASGGGASLAWFWRIGCEDS
VNELEGHTDTISCLSFSEDGQLLASGGVDACVKIWDLSGNLKSMFEGSAKQYEFEWVRWH
PSAHLVLAGCTDKTVWLWNADKGACINVFCGHGDHVTCGGFTPNGKSICTGSLDATLRIW
NPRSGQGNIVQGYREASALTCLSYTFDSTLALTGSENGFLSVVNIARGKVISSFSSHSGA
IECIGVSKSMPWVATGGVDQKLVIFDLQHSASRSIFEYQDGVTCLEWLGGESTYVASACG
DGQIIISDARSEENVRSFKGHSERIQQLAVSADNNYLVSASEDGTCRVFDISEFK
>Sgl71155 E3_activity/RING/RING 36.8 10.4
MESAGGSSDGHRDRERERGNSANSGLRRYRLPLQLSAANLIRSPVSTLLEYSGLLRPRSE
SEPLIGGNGTTSASHTHHDSSSNGGEVSIRIIGASEQDHDRIDQATATTTGGQLQPCPAD
VSAQSLPMAVSSSGTDGQEDLRSDRAANGDAHSGVSQFSSSSTDAEAADGGGANNRDANY
QRYDIQQAARWIEQVLPFSVLLIIVFIRQHLQGFFVTIWIAVFMFKSNDILRKQTALKGE
RKISVLVGICILFTLHVAGVYWWFRHDDLLYPLIMLPPKEIPPFWHAIFIIMVNDTLVRQ
AAMVAKCTLLMYYKNSRGRNYRRQGQMLTLVEYLLLLYRALLPTPVWYRFFLNKEYGSLF
SSLMTGLYLTFKLTSVVEKVQSFFAAVKALSRKEIHYGAYATSEQVTAAGDMCAICQEKM
HAPILLRCKHIFCEDCVSEWFERERTCPLCRALVKPADLKSFGDGSTSLFFQLF
>Sgl71158 E3_activity/RING/RING 25.8 7.1
MELNMQTTSQELSHLNFLDRIESGVANDQLHMSVTCGFCGRTLSLEDEVTSRLQRASVCN
DCKFLLLEDFGTPVHNSSRRRLPGSSVINGSPESVENFSQQFSQIINLARHVEHEHEDAR
GDTNLNTLGLQSASSRTTPNGSNRWWRILSDTESDGFNTDLFYGESESNFSGGAYRIYHG
DSDVISFSTYDGDSIASVDGPTNFDTDMYGQSLERSDIDSDTDIDPMHAGVVDWNSDEYQ
VEDSDWGEVDVRLQETGTIIDSSAGSDYFVERGSMDSFQFEEMISQRLGEIRYLQNARVL
TSMEDFGEAPHDGNSEDYLDTRRYEDFLERILETNNSRRGAPPASVSFIDNLPLVVVSDE
HHKHDGLPCAICKDLLVIGSKVTQLPCFHLYHPACILPWLRARNSCPLCRYELPTDDRDC
DWSKRNNSHGMIVSEIQHQQDRDDSSSVATDSSEIDETQNFAARMEDVGTAAELSHTNGM
RGGWLLRAAAPIVGLAGIVIVLWLGNPLAGRRGSTVQSNLHGWPAQPIHTSDLCPRNQQE
KRWWWWF
>Sgl71178 E3_activity/RING/RING 30.1 5.6
MAHRHIYNASQIFEAEPDQHWNLVHGEDPYLHFARSSSAENAPIFHPVENGPVDQAHYVS
PWNAATRLSGYSSPSPMVNPPPYQPDTPDPSRDLMHPSAAGNVFMLPENHVHHASSSNYG
VDSNFFDLSMGNGRGPYKRKCPAITDRGSTSRYYCPGSSSDVSSSSDLRQEKSAVDVQHG
HWDSVTVPASYRTNQLSIGGEPSIRNVRSRSTLDLEPDAFRTHLPANYPHHPSSSRHPID
HPSAVDPIQNSNVTLPEWNPIHVSGAPHGRTIVPSNLNHESNHFFAGSSIANSSGEMAGY
HHEHMASRNSLSQSLHPAPTHTRGVRSSYSHRSTPNSRASMGNLRMSHVAPPDDSLQMVG
ENHSTRHPRPFGPVGWRNGDRSGRSRLSCERYRLISDDAGVHERLTPEGLMIVDRASLYA
SRNNLDQHREMRLDVDNMSYEELLALGERIGSVNTGLRDDQVPRCMTETVYCSSDQVQEE
GRCVICLEEYNHLDDVGTLKTCGHDYHVSCIKKWLSMKNACPICKGPALPDTTKEK
>Sgl71197 E3_activity/RING/RING 30 5.6
MASRNSLSQSLHPAPTHTRGVRSSYSHRSTPNSRASMGNLRMSHVAPPDDSLQMVGENHS
TRHPRPFGPVGWRNGDRSGRSRLSCERYRLISDDAGVHERLTPEGLMIVDRASLYASRNN
LDQHREMRLDVDNMSYEELLALGERIGSVNTGLRDDQVPRCMTETVYCSSDQVQEEGRCV
ICLEEYNHLDDVGTLKTCGHDYHVSCIKKWLSMKNACPICKGPALPDTTKEKEISKMHGC
FIYYPFFVGLKRIDAAVDALTPMGFPPNLIRRKVKSLLKAYGEDGWVFIEEAAYKMLIEF
ILEEQEQCEQGEPSSRDSQIDEVRDQGGGEAEQTPLIEGSRDQGGIEAEQLEATPLIGGS
ESTWPNLDVATPMTVRDAPMDNPSLERRPCLGWMDPDDDDQSFILLEPAPVLGWGNSKEA
REAEI
>Sgl71200 E3_activity/RING/RING 30.1 5.6
MAHRHIYNASQIFEAEPDQHWNLVHGEDPYLHFARSSSAENAPIFHPVENGPVDQAHYVS
PWNAATRLSGYSSPSPMVNPPPYQPDTPDPSRDLMHPSAAGNVFMLPENHVHHASSSNYG
VDSNFFDLSMGNGRGPYKRKCPAITDRGSTSRYYCPGSSSDVSSSSDLRQEKSAVDVQHG
HWDSVTVPASYRTNQLSIGGEPSIRNVRSRSTLDLEPDAFRTHLPANYPHHPSSSRHPID
HSSAVDPIQNSNVTLPEWNPIHVSGAPHGRTIVPSNLNHESNHFFAGSSIANSSGEMAGY
HHEHMASRNSLSQSLHPAPTHTRGVRSSYSHRSTPNSRASMGNLRMSHVAPPDDSLQMVG
ENHSTRHPRPFGPVGWRNGDRSGRSRLSCERYRLISDDAGVHERLTPEGLMIVDRASLYA
SRNNLDQHREMRLDVDNMSYEELLALGERIGSVNTGLRDDQVPRCMTETVYCSSDQVQEE
GRCVICLEEYNHLDDVGTLKTCGHDYHVSCIKKWLSMKNACPICKGPALPDTTKEK
>Sgl71206 E3_adaptor/Cullin_RING/DCX/DWD 60.2 12.7
MMNSANGMMNPSSSTSTATTTSNIQSATCLKNYFKTPEGRYKLQYEKSYPSGLLHYTHGK
TVSQVTLAHLKDKPTQSTQATTSGAGVASGVRSAAARILGGGNGRALSFVGGNGGSRYAS
STSRNGSFGASSLSNSNNLNFDGKGTYLIFNVGDAIFISDLNSQDKDPIKSIHFNNSSPT
CHAFDPDAKDGHDLLIGLNSGDIYSVSLRQQLQDMGKKLVGTHHYNKDGTINNSRCTSIA
WVPKGDGAFVAAHSDGNMYVYEKSKDGNGETLFPAIKDQAQFSVAHSRTSKSNPTARWHI
CQGSINSVVFSSDGIYMATVGRDGYLRVFDYLKEQLICGGKSYYGALLCCAWSGDGKYIL
TGGEDDLVQVWSMEDRKVVAWGEGHNSWVSGVAFDSFWSPPTSDDSGENSVYRFGSVGQD
TQLLLWDLEMSEIVVPLRRAPGGSPRIGSPTYSTASQSPRWDSACPAGSLQPSPSMRDVP
KLSPVVIHRAHTEPLSGVIFAQDSVVSACREGHIKVWMRPVCTDNQSGNSESVLNVGLRE
KPVLVAKSGTSGFKP
>Sgl71214 E3_activity/RING/RING 22.9 13.1
MGNTGSSATSNGANRRRQNSRRHHPQPPPPPPQPQQQPPPSEVTPNRYVFAAASPYPSAG
YYQYHPPAPGYYPPPPPPPHHNGSIPMSMPLPAPYDHHHQGQGQHHPNWAAAGRFHYGPM
VPPSHPVPHPPAVATPYVEHQKAVTIRNDVNLKKDSLRVEPDDQNPGKFLVAFTFDATVA
GSITVIFFAKEGEDCKLTPMKESVLPPVIVHFEQGLGQKFRQPSGTGIDFSMFEEAELLR
EGDIEVYPLAIKADACPPTETGTDGEPVPGSINSQITQVVFEKDKGEYKVKVLKQILWVN
GMRYELQEIYGIGNSVESDFDGNDPGKECVICLSEPRDTTVLPCRHMCMCSECAKVLRFQ
TNRCPICRQPVERLLEIKVNNGNEEERSE
>Sgl71258 E3_adaptor/Cullin_RING/SCF/SKP1 100.3 0.3
MASNTKIILKSSDGVTYEVEETAALKSQTIKHMIEDDCADNVIPLPNVKSKILSKVIEYC
KKHVKSSASTPSTTSSSDHQHGQVVDDELKKWDADFVKGLDQDTLFSLILAANYLDIKSL
LDLTCQTVADMIKGMTPEQIRTVFNIENDFTPEEEAAVRAENPWAFQ
>Sgl71266 E3_activity/RING/RING 19.9 13.2
MTIRKRSSFTNDETEYKDEEIRKKSKQHEAGLNNKQQQQQLYKGMNNYTDYRACFRRAKA
AVVGPQRCSPHIRATTTYDYQPYVCKDYKETGYCGYGDSCKFLHDRADYKSGYQIDKEHE
LEESNRARKIVSGFDKLDDDDDDYHDNSVGSALACQICKRTFVNPVVTKCKHRFCERCAL
KHHSKTKRCFVCNQPTQGIFNVARDILKNSR
>Sgl71275 E3_activity/RING/RING 24.8 9.0
MPRRFRRSVDEFLGDHFIAVDEDYEEQEEDDEEEEEEEEEDEEEEEEVAEEQEEADYADD
SEVEEVFVHNPRNSAVMAPRVSEIEVRGKDDAVMVDSVPSSSGRDDDGEGEGCLNREEFE
GLICSICLEPWTSSGEHQPSCLSCGHLFGMSCIKKWLGQRRNSGKCPQCNKKCTLKDVRR
IYGSRVVVVDEESQKRIRFLEAKCDSLAKKDEEWRKKEVEWHMKVLVLQKKDEESCQKLQ
QANERVNYLERSIAEMENKSQISAATDGFHQSAGGPKSGLLYLPVSYHTFDLQQELVVDG
ARHFDVDDTGQMLIMARKLTRGGECHVLTKMSLVSPHEQDNVLLPSAVRDLHLSSFARLA
LLVSTGRKLSVFSMESNNCVVDYDLPAAAWSCSWDSNSSHYIYAGLQNGKLLVFDLRNTG
GPVESRNGLTCNPIHTIYSLLEDSPAHTGVKKLLTASQVGVCEWSIGGENEEPSLLADTA
NQGICVSLAHCPSSDNIVATFRPKVKAQDEPDDPRITQVSQVCPSFSLGNPVQGSQVFMQ
RVNSRYQKFASIPASVPSIRLPKSAIFGMGDGAHVFACVRYFNKAQSTMLLESGEIAVVH
SKIFVRETFSWSLGEFFGDLEDYKLSTVYDA
>Sgl71280 E3_adaptor/Cullin_RING/DCX/DWD 63.2 2.3
MSLIAGSYEKFIWGYKLKNPKTLKTLTLIPKFSYAAHLSPIKSVAISGIVAASSAGDDTI
KLYDLSTSSELGSILLESSITSLTFFAPQSLSSFPRNLFGGAEDGSLSIFDVDPFVNLKT
ISVHKRAINDIAVHCSGKLGLSVGRDLGLCMVDLVRGKKSFGCKLGNEATIVEYFCEGEK
FFMGFDDKVCVHDAEDAKLVGEFQVSKRVLCAAPGENGIIFTGGEDRAVTAWDTTSGKLA
YSIDDAHKSRVKGIVVLSRDNNSGATENPYLLSSASSDGVIRVWDVRVTNKEKSKPLSEV
DTKSRLTCLAGSSFKSTTKPETKDPTENNAEEMED
>Sgl71296 E3_adaptor/Cullin_RING/DCX/DWD 144.7 36.0
MVKSYLRYEAAATFGVIASLESNISYDKTGKFLLSPALEKVGVWKVRQGVCSKTLSPSLS
SPGPSLAVTSILSSPSSSSSLVAVGYADGSIRIWDLVKGTCETTLNGHKGAVTVLRFNKI
GSILASGSKDNDIILWDVVGETGLYRFRGHRDQVTDLLFLDSGKKLVSSSKDKFIRVWDI
DTQHCRQIISGHHSEIWSIDSDPEERYVVTGSADLELRFYSVINPDLEVGETLGSSGHKK
SVDDVPSSANNKWEVLKYFGEIQRQTKDRVANLRFNKAGNLLACQVAGKTVEIFRMLDEA
ESKRKAKRRVHRKKEKKEKKEKKEKEISKSVTEVTENGDQKNASVDDEGNPAIVVSDVFK
LLHILRSGKKICSASFSPINTKNSVATLALSLNNNSVEIYSVESDSSTQSLAIELHGHRS
DVRSLSLSQDNSLLLSTSHNAVKIWNPSTCSCLRTIDSTYGLCSMFVPGDASNKYALVGT
KGGKIEIIDVASATCVEVVDAHGGSIHSIAGLPDKSGFVTGSADHEVKFWKYERLQKSGE
DLERLTVSHERTMKMNDDVLKIVLSPDAKYIAIALLDCTVKVYYVDSLKFFLTLYGHKLP
VMCMDISADGDLIVTGSADKNIKIWGLDFGDCHKSIFAHADSVMDVKFVANTHYVFSVGK
DRLLKYWDADKFELLLTIEGHHAAIWCLALSSRGDFIVTGSHDRSIRRWDRTDEPFFIEE
EKEKRLEEMFEGDLDGAHENRYAPKDELPEEGAVASAGKKTQETLSATDLIIEALDMAEV
EIKRIAEYEEEKRRGTSTKFQPNLLMLGLSPSDYVLRSISKVQPNDLEQTLLALPFSDAL
KLLSYLKNWTSNSEKVELICRVAIVLLQTHYHQLISTPSARPVLSELKDILHARVKDCKD
TLGFNLAAMDHLKQLMTMKSDAPFREAKTKLLEIRSQLAKRNAGTTDTREERKRKKKQKK
GSDGHAWTVVR
>Sgl71316 E3_activity/RING/PHD 37.5 23.9
MKRELAALETKSPIKSPMVDSIGRKTRASTRSSGAPLSGSLVYKRVKRSHVKKAELLSNG
DNGVSDDVSKENGGVGKQNGVHDEGDEVEKGLVVLEESGNGVAAGVCSEVVKEVCDEGVK
KSEDSMAAEEGVKESEDSMVVEEDGVKDVLPISVIVMGVTAVDGVMSNVKSNDVEVNNGL
VEEEEGSKKGGNAELGDDLHGNGGSIEVYKEKVVKGKKSALKGVNGNAKSNSVEYPRRFT
RSALKSKVDTVAVGSEIVENGENTKVVGEESNGEVRSELAIVVYQTPESKEEVKVSPAPK
FTRRLTRSASKSKVEGSTVCPAETVTLDSEKGALVVRNDNAECDMDKLDEEELSSATPRR
KLEMKMSKQISPTKTPTTVLELFGTGMLEGCPVYYDGGKGRELHGRIRGIGILCSCGTCK
GMKVIPPSMFEIHACNTYKRAVQYIYLENGRSLIQILKACKNNRFNSLAATVQNAIGPLP
DKKVIVCQNCKESFSTMDAESSEPVCSTCVMSNLSPIGPVYSSRKRSRSSNVFLPCQAAS
ACDVVQDGSEQKGVQKSPKASRTPKLKTSQVDLPSDMLQSRRRPKSVKKSADGFVTPTLR
RSSRVEKNSETKTSAETVKRSEEASMVPNTSSSPVLGSSEAKHRNKLKKRSFKSALSPKP
SKSTRMEKCSPRNDGAKSTERLKKRKKESLTPKPSRTPALRSSEKKSNGKITRKDLRLHK
LVFEDDVLPEGTELGYYARGQKLLDGYKEGSGIHCNCCDTVVSASQFEAHAGCASRRKPY
CYIYTSNGVSLHELSVTLIKDRRHSAKYNDDLCSICADGGSLLLCDGCPRAFHKECASLP
SIPVGKWYCKYCENMFEREKFVAHNANAVAAGRVSGVDSIEQITKRSIRIVNNLASEVSA
CILCRGHDFSKSGFGPRTIILCDQCEKEYHVGCLKDHNMADLTELPEGKWFCSVDCGKIE
SSLQNLLVRGVEKLPEYFLDIIRKKSMRSDSRTKMNVSWRLLTGKIATPETRTLLSQAVA
IFHESFAPIIDVVSGHDLIPAMVYGRNVGGQEYGGMYCAVLTVNSVVVSAGIFRIFGPEV
AELPLVATSSGNHGKGYFQILFACIEKLLAFLKVKTIVLPAAEEAGSIWTDRFGFTKMTS
DQICELKRNFWSMVRFQGTSMLHKLVPESPVTES
>Sgl71325 E3_activity/RING/RING 27.8 13.4
MEEITSSIHKKSSKNNYLPILVISVGAIITTSVALSLLHIMFIKYCKRRHDRSSQTLNIE
QSSVSIGLDKRVLNTIPILFYSSKTRDLYRVNQGDECVICLQQLNKGDLIRCLPSCGHVF
HVPCIDHWFHAHITCPICRARVRAPRSRTRALPRTRSGGVLRHSTKLVLPIQGLGPRDLV
NVGLKRSLSMDECCVVIDTNEEQTSSSSSSSSSSSSSSTLGSSMINTNINPCTNPPLSKI
EFLISRLYHANSYRRFNYVPRSLHGLREGRGGTSRNNGILPY
>Sgl71343 E3_activity/HECT 339.3 0.0
MDDSKKNLVSLRGASAREITRDALLERVSHEREQRNFARRANSAALFIQRVWRRYNVTMK
VALKLQEDWKVSVQDASGKMKKSWISGFLLRPFLFFITPLSLRQGTIQSQAVNSMRSCFV
ILLENLNSTDPEINFCSLAMGTIEEQRIWSYQVKKLVSLCSFILLDYDSYSVRNSDVAAV
TALLMRLVITLTDSRAWKCIPDEKREDANRAVKDLIRYIGCDKSGLFRSIGRYMTKLNAS
LTSQSVVQKDDKFLITASAITLVLRPFLAFNSDGNDPLPLDVRFAAEQYCLFILTVPWLV
QRIPAAIVRALKHKSILMPCIETLLILNEKILMEYSRMDLSGVSTNNDMPCVGWVISNII
SLVTESENGSIQSSSFTDGINIVGYVHVLNILANRLLTEIENNQFKKKGRLEVEDGTATG
TLVDKTFGSLNYMDLLRPVCQQWHLSKLMATAKSKISTAVTDSSMSISGFKRIKVLELVD
IAHCYSFIIRIYSALNLMLGPLPVLNMLSFTPGFLSSIWGALEHAVFPEAALVFEKDMYN
ASEMHENRSAGTSKRKQKQPIKDGAAKWVNVLHKISGKSQTDADNGSDANYSQAGVSQGK
TDLDDIWDVESLRCGLESISKEKSCLIHLFCATYAHLLLVLDDIEFYEKQVPFTLEQQRR
IASMLNTLVYNGLLHNTGRQNKQILDAASRCLQMLYERDCRHRFCPPALWLSPARKNRPP
IAMAARTHEVQSDVRSDDNLTFQSMGSFITVTPHVYPFEERVQMFREFIKMDKTSRRMAG
ELNAPGERSVAIVVRRGHLIEDGFQQLNSLGTKLKSSIHVSFVSECGLAEAGLDYGGLSK
EFLTDISKGAFDPQYGLFCQTSTSERLLIPNTAARFQENGIQMIEFVGRIVGKALYEEIL
LDYSFSHVFVQKLLGRYCFLDELSTLDPELYRNLMYVKNYEGDVKDLSLDFTVTEESFGK
MHIIELRPGGKDTSVTNENKLQYIHAMADYKLNRQMLPLSNAFYRGLTDLISPSWLKLFN
ASEFNQLLSGGKHDIDVDDLRKNTRYTGGYSEGSRAVKLFWEVMTDFEPKERCMLLKFVT
SCSRAPLLGFKHLQPTFTIHKVVCDVPLWAAFGGQDVERLPSASTCYNTLKLPTYKRAST
LKAKLLYAINSNAGFELS
>Sgl71441 E3_adaptor/Cullin_RING/BCR/BTB 21.2 0.1
MAATTLEEEDDWLVIECTDPNTIQRSSDIVTPAEILISTADISSWDLPFILTHRIVRVNV
NRSRLIEQSSYFQSLLSGNFSESSMCCVSVEWSLETFLLILRFIHGCHIEVTNCNFLPLC
HASLYFGLDRLVLECRNWFSNIVTTVDNLKLDELIHFWEFGFDQAIDWISAVCISHVAKN
FMWALSCETFVALPFEFLVSCVKHPHLTVDSERHLCEALLAWVRADMEPLEYTCSLNYDS
GEKSKQITHDCTRILDEVRVNLLPLWFIMGSSKYWYFSIIAKQGVSAIVNRLNRFFKDPK
YIVDARDQSYMRIRLTDYSKKLDLSGCPQISSSDILFSMLQQTTSVGLLLEGIGQKSVDL
ECPKWLSSLTTVSCEEMMEVDISKCSLLNLGAALECFRKSFPFLRTIRMAYFLDFETKRL
RQLLESNHSICEVDLTVDVSPLISSNISVLHSEPVSRSSLKRYFDMSSCRGKETKSNITK
LTLEGRSDFSDRELLHIADVCISLCYLNIRGCSAVTDVGIANLILKCRKLHSIIATDTSF
GENSASALCSRFQDDGCSQMEINKHHIELSDIYLEVLHIGGCKGVSETSIGDILSRGRMI
KNLCLSDTLLVDQVLYRFPGSSLEILDLSNTMISRDALSYMLNKNLGLKYLNAKGCNKLC
ADQFKLKEDLFSSDPCDQWFKLLGQECKLEELIIGWGFSFFSLNSLGPALKSLKTINVGL
GGSLGPEGLIKLCTLSPLLESVTIVFQVICDTLIMNLLGTLRNLQALSLCYCIGDISPLS
LKHSVPSLRILKLERVTPWLTNDDLALLTQNFANLNELSLVGCTHLGEDSQRIISSGWPG
LISLHLEDCGDVTAKGTGFLFNCMALEELLLRHNGPGIQKDFVLDAASGLPMLRSISLDL
CDAIEGEFDLPKFADKHSLSNVKISRCKLQKCTLDFQCVEAHKRPVHKETLVLEWNSNRK
SSLLKLKGDQWLQLKLERPVLWEFGMLLSQLQTSVAAHESSLGCLSSFGKPKHAAYTRLY
FPSSCDINELSILASKEV
>Sgl71463 E3_adaptor/Cullin_RING/DCX/DWD 34.7 9.7
MEVQNIHRKPMEEVENNKRMKTGNRKIREVAESQGSEAAAAAAAAAATVPLIESTPTETS
KATSSHDNSEIRVSMFDHCVENHFKEMDMIFKLCGEEETGGLVDEEIERIASSITFLREW
RYFNYRPRTIRFASETGCPGGIKAHNEITLSQFSAAVVPDCDAEAKNGPGGVVSSNDSRK
DFALYVGGLVWSLDWCPRIDQETISGSKCEPFVCYSIPEFIAVAAHPPDSAYHKQGAPLS
GRGMVQIWCLYSHMTQEDMKAPVGKIKKKYKMEKVANKEENKPVRPRGRPRKNPVVKDPA
KDPEGPFTQAIVVHLPEKSSVVPPADETMQSIYNDITPVSEKDKDQINAENEILTNNANE
EKLQEEEKNPKKPRGRPRKNDKTSIEDPEGQIIPALAVCLPEDPLSGPPMDKNMPSDSAP
KKGKERKRKAVNDGTIPKENTSGIPSSEGPSVQEVPECIKNISPAENCLLYTNGVHENMG
KKRMRKGVLVTDLECTLAVLRRKSRNKPKVCNSLDTENTVLSIHNEGEEPSLASLEENYL
RKDNRITEGNDLGNNLSDLACVGCHIQEKDVLPRVVLCVGHDGKVAWDVKWRPLNGDVAA
NKHRMGYLAVVLGNGSVEVWEVPSVKVINRIYASRLAKGTDPRFAKLKPVFRSSILKYGG
KNSMPLMVEWSTSPPHNLLLAGCHDGVVALWKFSVDIPSEDARPLLCFRAETGPIRSLSW
APYEGDPESSNIFVTAGHGGLKFWDLRDPFRPLWDANPSQRFLYGLDWVPDPRCVLVSYD
DGTLRMLSLSRAAYDVPVTGQPYSGTLQQGLNSYSCSSFAVWSIHVSRRTGMVAYCCADG
TVLYFQLTHKAVDKDPLRNRAPHFLCGSLVSEESTVTMNTQLPDSPHQMKKSATEWSNTP
RPSRTVASRKVQAKRTRKGTEKSQNLDDQVLALDYGDDTESRVTNETQMSTKDGKGKTSS
SKAKDDQAFMSSVDDGENTNGKPEVKEEANKAFEAFPPKEVSMYRVRWNLNKGSERWLCY
GGAAGIVRCQEIVAPVFDKKSLRWSKP
>Sgl71479 ULD/UDP/UBQ/UBQ_PIM 95.3 0.2
MQIFVKTLTGKTITLEVESSDTIDNVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLADYN
IQKESTLHLVLRLRGGAKKRKKKTYTKPKKIKHKKKKVKLAVLQFYKVNDSSKLQRLRKE
CPNAECGAGTFMANHVDRHYCGKCDLSRASSIHGKEDIETLPHMMGELLHLRYLDLSRNA
KLLELPNSITQLYNLQTLKLEECSELKGLPRESRKLVNLRHLDIKWCRSLRHMPPGMRSM
TSLHKLSMFLLGSNNVGSGSLSAGYAGKLEELKYLNNLRGRIEIAFRDGWMLGLKNYPGV
AFPGWGQPQFSDLDLNTALPNLVHISLYRCRRVERFPLFSQLRHLKFLELEDLWKLEYVE
NRSFSRKAELVFFPSLEDLVLRNLKELKGPLLVPEGNIYNSSSNIGGSDHRNEEDNDAWR
CLTPTLRHLKLDQLPKMAKLPKGLQHLTSLHSLVIIQCNNLEEIPSWIGRLSSLQHLSIR
YCETIKSLPDEMLHLTCLTQLKLCGCSQEFKERCKKPTGADWPKIQHIASIDIY
>Sgl71482 E3_adaptor/Cullin_RING/SCF/F-box 20.1 0.1
MYSLCYVYLPENIIFEILLRLPPKTLIQCKTVCKQWKSIITTPFFARSQLRFLKQQFNLP
PYYLLCSYDWSFALHLNRSYYRQNISPKELDDQVLPLSSKSFKLTSSEDVLLSTCNGIMC
FYLKKKNSLCLWNPTIDETRFVALPYESYWIRKFYFAGFGYASSIDDYKIVLAAKYACHT
INTSTDRRSLSVYSLRRNEWRELDFDYYKSIAPEIYSGLGWRSGRQESNGIRMESIVVND
ALHWLMDSCIYNTYMKLFLYKFDLVNERFEKVVDLNKISNIVDDENRLAPRQTEIGVTEN
NTLIIYRLYSEFCHSNPSNELQVKRDVVKAWEMADQYDYNSWKTKLRYVGDWDDIRDNHD
LLQITSNGNVLIIGGIFAEYKSRLWFGQYSHKQRAQDVAFYAKYYVPSLISPNNF
>Sgl71495 E3_adaptor/Cullin_RING/SCF/F-box 11.7 0.0
MSDILPEDLWFDIFLRLPIKTLGICASTCKTFNSYITNPNFIASHLKISKEKKTPIFFLR
YYAIESEAKRRGSSNELFGLHPDDESLNWDFNMKKLPFKTHARCFHILGSCNGVICLSDD
VEGYINKFYLWNPFIRKHILLPYPNVMFSTHGAYEMCLGFGFDELANDFKVVRVVYLDDY
SYDDPPLVEVYSLKLGSWKNVENSSPELVIYDSRTMIYSQCFLNGAIHWMGSKGFSGRPY
VWAGIVTFNVADEVFGVMKLPSSLDRSSTQKKLRISTCWGMLAVIQSLCDKICIWVMKEY
GVVDSWTKMFTLANPIMGSFCTSISFRKNKDILMLGTKMGSNRRLCHTMHSVKQNGSMIE
ELGTFYGSVVGFYLDVYEESLLLFNEGKPTFSNDEDVQDDNVVQNDELADADAEELQDD
>Sgl71552 E3_activity/HECT 324.7 0.0
MEDSLTESRGQKRSDMTEELPADKRACSSLEFRPSSSTVTPETLVSSSSTAVEAHGGDME
TSSSSASASGHSEGDGDRDSPYGSCDSDDMDDDDDHRYSSLRALQRSRSYNDSSKFDRIL
SSLSSDAEPSGQLAALTELCELLSFCTDDSISSLVADQLTSALVKLAKHEDNPDIMLLAI
RALTYSCDAFSRSSGLLVRHDAVPALCQKLLVIEYLDVAEQCLQALEKVSRDHPITCLQS
GAIIAVLGYIDFFSTSVQRTALRTVVNICKELPSEYSSTVMDEVPKLCELLQYEDQQLVE
LVATCLIKVTNCVKDSPEKLRQLYDRGLINQVTHLLELNSRITLSHTTYTGLIELLATIA
SGSPDAVKTLFELNIGSVLKDGLSKTDLSHGTPSPRSVDNNCTQVLEILKLLHELLPDVA
KDEKELLSFTERILLDHPDNLQTFGVEILSTLLQVVSSGANLYVCYGCLSVINRLVYLSK
PETLLKLFEGINIASFLAGVFTRKDYHVLLIALQISDTVLEKLSSILVPAFVKEGVLFAI
DNLLMPDSCSQQSFPKISSSQSVKKIAGKGAMRCFCFAYHNRQLKSTPDSETCKADKDSV
HSLAKHVKSKHFIAELLGPQSMVTDLLQDLRNASLEMNDILTVSPAKESDSHTDDRLCRN
LEKIILQLGGNAPVSTFELIESGIMKALLNYLSYGHFLSNALKPNDLTHAYGVQKRFEAF
ARISLSSPDPASTGLPLSFLVRKLHSALSNVENFPVVAGFGTKQRGSYATVPSGRSIMHP
CLKVRFLREEEELCLRDYIKDVVTVDPFCLVAEIEKCLRSKVIQRKKGSSESQLQSSESK
PKAEEVLHDISSLPGKSVELQGSGSMCTVSPDMQEDGDGKSLCSAMETSNLGQTTVVGAR
VTSEVQSKTQEDKDHSSDGADNMTEISSTCLNADVGNSKDQSQVCSNNEDTPKLALYLDG
EQLDYPSTLYQEILQRQIKSHHELHNSSKLWSSTYTVTYRRVEENESVSKKGREMHDNGT
IDEVLLCQQLMPLFSSIFVDKLGSKLDLSSSSSDILLLLKSLEMMNRFAYHLVSYERMRK
FAEGQLHSLDDLKGSLPMLSQYEFVNSRLTEKLEQQMRDSSAVHVGALPLWWCQLIARFP
FLFGFEARCKFFQLAAFGRVHALPYTSSLTDSSMSRDRRTSTGSPPRKKLRVHRESILES
AAQMMDLYATKKVAIEVEYSEEVGTGLGPTLEFYTLVSHEFQKAGLGMWRGDYMSLTNSC
NQQGSNSGYVVSTSGLFPRPWSSTSSSINGIEFTDVIKKFILLGQFVGKALQDGRVLDIP
FSIAFYKLVLGKELSICDIQSFDPQLGRTLLEFKALASRQKVLSPACSENIVLGDSKMFR
STNVEDLCLDFTLPGYPDYALSSGMDDEMVSDNNLEEYISLVLDATLQTGVSKQVEAFKT
GLNQVVSDKHLQIFTEEELERLLCGERDSGLSVDLFDHIKLDHGYTAGSPPVINLMEVIS
EFTYDQRRSFLQFVTGAPRLPPGGLAALNPKLTIVRKHSSNCPDADLPSVMTCANYLKLP
PFSSKEILKEKLLYAITEGQGSFHLS
>Sgl71605 E3_adaptor/Cullin_RING/DCX/DWD 52.9 15.8
MEPPECPVCLQSYDDITTIPRVLSCGHSACQTCLTNLHHHSSSHSLLPHTLRCPSCTQLI
KFPHPQGSTALPKNIDLLRFLNQTPNLTPPINDNNSLINVRFSGFKPKIWSDEVYAAWKD
WILPNCVVVRNDEGNGRINVSSDFVGLNLSTVMRCLLVGNQEVGLVCIGRFELNDHETDP
LFEYSYLGKIMNVLCQMDEAQRNEISSLFGKSLRNSKVCKVFGLWLDVENDGRLFLVTNK
MKNALLNLENEIGEDNESFGLYLGSIGVELCEVLMSLHSEGFVCGCLGLSCLCLDEFGHV
LLDIGEALVVGRKLRECVVGVISGMKINGSEAEALVKMSNMDVFVSPEILLELLHRESFE
INKKDESSAISYASDVWLVACSVIRLLIGNRFVVVFSNYVRELFQEMSEGFSKCKIIYLK
WVETIKDALKPLMVGNYGLMHEILLKCLDFDPQNRPLAIEVWKSFRGLNMHHSLIHVSSL
GSESTKDDIDQCLVLGDLCNVSNDQRKDLRISKLSDEHDDCKSDTTVDREVGIDNVVKVL
SAGKMQCKDLQGHRDCISGLCVGGGFLFSASFDKTINVWLLQDFSHVHTFRGHEHKVMAL
VFVNQAKPLCISADSGGGIFAWEVNESLTQEPFVKWYEEKDWRYSGIHALTVSESGCLYT
GSGDRLIKAWLLKDHTLLCSMEGHKSVVSTLAIFNGVLYSGSWDGTVRLWCLHDHSPLGI
FGENTPGTMSSVLSLFADQNMIVAAHENGCIKIWMNDVLKTSTKVHNGAIFALAVEGKWM
YVGGWDKTVKVQEIARDESEMEIIDVGSIACDSIITTLLCVQGILFVGCANKLIKVYHCG
M
>Sgl71718 E3_adaptor/Cullin_RING/DCX/DWD 145.6 26.7
MNSQSNEGEIEEHGDVFLDESDIIQEIPFDDEELPEADEELGSDEEHVETADDSMHTFTG
HSGELYTVACSPTDPTLVATGGGDDKGFMWRIGRGDWAFELQGHQNSVTSVSFSADGRLL
ASGGFDGLIKVWDVTTEELKCTLGEPGYKLGEPGSGIEWVKWHPRGPVVLAGSEDYSAWM
WNADQKDGRPRVFSGHGGVVTCGDFTPDGKKVCTGSNDASLRIWNPVNCAIIREIRGYPY
HTEGLTCMAISPDSAVILTGSTDHKVHMVNISSGKVIRSLTAHTDSIECVGFSPSGQWAA
TGSLDHKLIVWDLQHSEPRNTFLHEDGVTCLAWLNISNPSRYIATGSADGKVQVWDGLAG
GNAAIRTFSGHTEGVQSLSISADGNFLVSAALDGTARVFEIHEFK
>Sgl71799 UBD/UBC-like/UBD_UBC 112.8 0.0
MKLCPREVEKLALHNAGFLAQKRLASGLRLNYTEAVALIATQVVVHSEKFYNFRSSVFID
FEFCSCWKQECGGTDGHWKEASWKGPSETPYDGGVFQLAFAVPEQYPLQPPQVRFLTKIF
HPNVHFKTGEVCLDILKNAWSPAWTLQSVCRAIIALMAHPEPDSPLNCDSGNLLRSGDLR
GFQSMAKMYTRLAAMPKKG
>Sgl71828 E3_activity/RING/PHD 35.1 10.8
MKEKAITPSNMISRNWVLKRKRKKFHGGPDVSVSKKEEDNVGADSAGGVCLTKELQNDNL
NFERSASKRKGNDGYYYECEICDLGGSLLCCDSCPRTYHIECLDPPLKCIPNGKWECPAC
VRKMDSSGSVCHKDLTSKRARTVNLSEKLNDGGKPSNALKVSHFPGKTVVKKRSSSKRNS
GLHARDQSIKKLESPRIDWSCGSKMGLVSDDGSVGPLLACENEDGDRKLHTGTQDYEEIS
DASAADEKSNCLTEHKVSFPEPKSETANKREGSNKNQCTVKNTASAPGVVSASKKKHKSI
KEKNKKKSNICTEEPSINRGQKRKSDASSPKISKPQRKRRSVHCRVSISKENVVSGKIES
QQEEVVVVMVVVGFWWADCGHVVLVCGLGGCSCGGGWVL
>Sgl72016 E3_adaptor/Cullin_RING/BCR/BTB 64.2 0.0
MDCGEQRSRRSLKRKLEHDFHENNNHHQCSSSSSSKVNEVCDVSRSPKKQAKKNHKDLLS
EINFHVQILHHCCPLSVSDRIELKRSAQFISELAKNEDMVDLIVDCGAVAPLVKHLQSPP
ENGVSKAIEHDVEKGCAFALGLFAVKSEHQQVIVDAGALPHLVTILKSHKSGCNSRSVCG
AVRRAADAITNLAHENVRIKSLVRIEGGISPLVDLLESSDVKVQRAAAGALRTLAFKNDQ
NKNQIVECNALPTLVLMLRSEDPVIHYEAVGVIGNLVHSSPNIKKEVLQAGAVQPVIGLL
SSCCSESQREAALLLGQFASAESDCKVHIVQRGAVPPLIKLLQSPDAQLSEMAAFALGRL
AQDSHNQAGIVQCGGIMPLLELIDSKNGPLQHNAAFALYGLADNEDNVADLIKTGGIQKL
QEGDFIVQPTKDCVTKTLKRLEEKIQGRRVLNHLLYLMRIADKTVQQRIALALAHLCSPD
HQERIFIDNNGLELLLELLESSDFKQQQDGSVALYKMAIKATVLTPVDAAPSSPTPQVYL
GERYVNNSTLSDVTFLVEGRRFYAHRICLLASSDAFRAMFDGGYREKDAKDIDIPNIRWP
VFELMMRYIYTGSVNVNLDIAQDLLKAADQYLLDGLKRLCEYAIAQDIAVENVTLMYDLS
DAYNASSLKHSCILFILQQFDQLSSKAWYPHLIERIGPEIREFFERVLTKPEVVEMIQT
>Sgl72037 E3_adaptor/Cullin_RING/DCX/DWD 95.9 16.9
MGQYVSRLETDSEESGEYDTSNNGNSSQVLDCSNCLENEISQLTKVKSKPNEHLVKIVPG
KRKRSVSTVNMLAGREANFSGRGRFTSADQCHVASRFLPVRGPWLVDQMNSRAYVSQFSA
DGSLFVTGFQGSFIRIYNVDREWKVQKNIQAKSLRWTITDTSLSPDQQRLVYSSMSPLVH
IVDIGSGATDSLANVTDIHDGLDFSEYGEYGYSFGIFSVKFSTDGRELVAGSSDDAIYVY
DLQANKLSLRIPAHDSDVNSVCFADESGHLIISGSDDNLCKVWDRRCFNAREKPAGIMVG
HLEGITFIDSRGDGRYFISNGKDQCIKLWDVRKMSSNVDNRERARRTYEWDYRWMEYPQQ
AKDQRHPNDQSVSTYRGHSVLRTLIRCYFSPEQSAGQKYIYSGSNDGSVYIYDLVSGVLV
VKLDHHMSSVRDCNWHPNYPMLVSSSWDGTVVKWEFPGNDEMPHSSNNRVIWRQQVI
>Sgl72148 E3_activity/RING/RING 13.2 17.6
MLPWGGFSCCLSAAALYLLGRSSGRDVEALKSVARVNQLKDLAVLLDAASKVIPFIVCVS
GRVGSETPVKCEYSGLRGVIVEETAEQHFLKHNDAGSWVQDSALMLCMSKEVPWYLDDGT
GRVFVLGARGATGLELTVGSEIFEESGRSLVRGTLDYLQGLKMLGVKRTERVLPTGTPMT
VVGEAIKDDVGTVRIQRPHKGPFYASPKTIDQLISNLGKWARWYKFASMGFTVFGVYLIA
KHALGLILERKRRWEINKRVLDAAAKRRDDGKDESGSDSVKRDLMPDLCVICLEQEYNAV
FVPCGHMCCCTRCSSQLSNCPLCRRRIDQSVRTFRH
>Sgl72291 E3_activity/RING/RING 32.4 6.0
MAEETSIPESHKSSCSAPINREDFGKLEFGCEHYRRRCRIRAPCCNRVFTCRHCHNEAMS
SQSNHKEHHELVRRDITHVVCALCDTEQPVQKFCSSCGVNMGEYFCEVCRFFDDETEKNQ
FHCNECGICRVGGRENFFHCPKCGSCYSISLRDNHECVEDSMKNSCPICYEYLFESTKVA
QVMKCGHAIHQECYIDMLKQNQYRCPLCSKSSLDMTSDWEVLDQEIESTIMPDEYRYEVS
ILCNDCNGTSIVNFHILGHKCSQCSSYNTRRKL
>Sgl72428 E3_adaptor/Cullin_RING/DCX/DWD 94 15.5
MGILECRKSESSPKRRKLCKSSMAMENNSSIGLGTKGLIKKHEFVRVIIQCLLSLGFPKA
ASCLESESGISCKSKEFESIESNILNANWDECLKFFNGIKGLSDETRSSAMFLVVRQHLL
ECLNRGDDSTALAYLQKRVSDLRLGTDKVRDLAFDILFSKEKGAGETNDDFYSLRKKLLV
ELEKLLPPPITLPEKRLEHLVETAVTSQIESCLYHNSSGAVSIYKNHNCSRDEIPTETIQ
ILTAHKNEVWFVQFSNNGEYLASSSSDCTAIIWKVVDDGKFTLKHTLQSHQKAVSFVAWS
PDDTMLLTCGNLEVVKLWDVETGTCKHTFGDKGFIASSCAWFPDSKRLVCGSSEAEKGIC
MWDCEGNELKVWRGARMPKVLDLAVTSDGEYLISAFSDKEIRILNLGASTERVISEKHPI
TSLSVSADGKFFIVNLNSQEIHMWDVAGKWREPLKYTGHKQNQYVIRSCFGGLNSSFIAS
GSENSEVYIWNRQKSEPIAILYGHSLTVNSVSWNPKNPHMLASASDDQTVRIWGSIKCKP
GQALDPESF
>Sgl72669 E3_adaptor/Cullin_RING/DCX/DWD 106.8 19.3
MAFECQETSEICLSKKSLNSVVHNNQVKQHFGKTPVYCVKKKTVWRKKGEKSETLVPKSE
LGIVGDLAVDHLVKLVTADEGDSSGYGRSITDLPPALVSEILNCLDPKELGIVSCVSTTL
YKIASDHSVWKDFYCERWGLPITKSLNLDVADEKSWKELFVEREYRSKTFLGQYRPDFLS
GHTEAVRSVFLLVSAKLVFTAGYDSVVRIWDLEEGLSITSSRPLGCTIRAVAADTKLLVA
GGTNGFIQCWKAVEGVSHLFDLKGSICENSEFRLWEHDGPVTSLVLDLARIYSGSWDMTV
RVWDRALFKCVMVLRHSDWVWSIAPHGTTIASTSGSDVYIWDTNDGTLVDIIPHAHEGNV
YALARSHTGDFIFTGGEDGSIHMFEISNSAEDGIFKVASWVPHSGAVNSLAFEFPWLVSA
SSDGKLALIDVRKLLKSTRSSLMKYRNKKVATIEPPQRMLHCSGCSLFSVDIGADRIVCG
GEEHVVKLWDFSHALERLMRSRAQRAIRLENKMRQRRLQAEMNAKNGKADKCSVAAKKNP
INGDRNCNWHNKRTVNGKMKA
>Sgl72677 E3_adaptor/Cullin_RING/BCR/BTB 73.9 0.1
MSEPSTAVISPTSSRVVTETVNGSHKFVIQGYSLAKGMGVGKHIASDNFSVGGYQWAIYF
YPDGKNPEDNSAYVSVFIALASEGTDVRALFELTLVDQGDQGKHKIHSHFDRSLESGPYT
LKYRGSMWGYKRFFKRSMLEQSSYLKDDCLKINCTVGVVVSSVECPRLHPVRVPESDMGM
QFGMLLENTDGTDIVFNVAGEKFYAHKLVLAARSPVFRSEFLEKLEEGSEEITVTDVEPK
VFKAMLHFIYKDDLVEEAELTPLSSCESHIADLLIGKLLAAADKYGLGRLRQLCESSLCK
CISVNSVGEILALADCHNATELKAVCLRFAAENLAAVMRSDGFEYLKEHCPALQSELLKT
VAGCEDDCSSAGGKSRSVWAQLSDGGDTNDRRVRPRT
>Sgl72692 DUB/USP 239.6 1.2
MTVMTPAPIDQEDDEMLVPHSDIADNHQPMEVVAQAEPANNNNNTNDDNSNNPENQAAED
PQSSRFTWRIENFARLNAKKHYSDVFVVGGFKWRILIFPKGNNVDFLSMYLDVADSVNLP
YGWSRYAQFSLAVVNQIHNKYSVRKDTQHQFNARESDWGFTSFMPLSELYDPTRGFLVND
TVLVEAEVAVRKIVDYWSYDSKKETGFVGLKNQGATCYMNSLLQTLFHIPYFRKAVYHMP
TTENDIPSASIPLALQSLFYKLQYSDGSVATKELTKSFGWDTYDSFMQHDVQELNRVLCE
KLEDKMKGTVVEGTIQQLFEGHHMNYIECANVDYKSTRKESFYDLQLDVKGCRDVYASFD
KYVEVERLEGDNKYHAEQYGLQDARKGVLFIDFPPVLQLQLKRFEYDFMRDTMVKINDRY
EFPLQLDLDRDNGKYLSPDADRSVRNVYTLHSVLVHSGGVHGGHYYAFIRPTLSDQWYKF
DDERVTKEDVKRALEEQYGGEEELPQTNPGFNNTPFKFTKYSNAYMLVYIRESDKEKIMC
NVDEKDIAEHLRERLKREQEEKEHKKKEKAEAHLYTIIKVARDDDLTEQIGKDIFFDLVD
HDKVKSFRIQKQTPFNLFKDEVAKEFGIPVGQLREVSNKVHNAELKLFLEVELGIDLRPI
PPPEKTKDEILLFFKHYDPEKEELRYIGRLFVKATGKPVEILETLKELAGYAVEDGIELY
EEIKFEPNVMCEPIDSKLTFRGSQLEDGDIVCFQKIIPTEIAEHCRYPDVPSFLDYVHNR
QVVHFRSLERPKEDDFCLELSRLHTYDDVVERVARQLGLDDPSKIRLTSHNCYSQQPKPQ
PIKYRGVDHLSDMLVHYNQTSDILYYEVLDIPLPELQGLKTLKIAFHSATKDEVTVHTIR
LPKQSTVGDVLEDLRLKVELSHPDAELRLLEVFYHKIYKIFPPSEKIENINDQYWTLRAE
EIPEEEKDLAPYDRLIHVYHFTKETAQNQMQIQNFGEPFFLVIREGETLAEVKLRIQKKL
QVPDEEFSKWKFAFLSLGRPEYLQDTDVVSSRFQRRDVYGAWEQYLGLEHADTAPKRTYS
NQNRHTYEKPVKIYN
>Sgl72703 E3_activity/RING/RING 29.4 9.9
METPSMEDNKKLEEAKLTSAAAFVEGGIQEACDDACSICLEEFSDSDPSTVTGCKHEFHL
QCILEWCQRSSQCPMCWQPISLKDPTSQELLDGVVQERNLRLNPPRNAAIFHHPALGNFE
IQHLPVGVNDAELEERIIQHLAAAAAMGRARHFARREGHRGRSSTQGRQQFLVFSANPNA
QGVPEGGQAEHTQDGSAVTPSLLRIGEEASPQLSSPNYSTQTDMVSSSGTSSTPAGHASP
SDSGRSPGQSSPQNQDRAGPSDLQSFSEALKSRLNAVSTRYKESISKSTRGWKERWFSRN
SPMSDIGTEVRREVNAGIATVSRMMERMETKDNEGPSNDSVPDSSGSSQTRDSGSQHGTD
SVASPGENHLNDNRTQTSCASHSGSN
>Sgl72711 DUB/USP 363.3 0.0
MDSISSEDSTTAPQPIPNDEQRVYLVPFRWWKEALDASTSDSKGVLYSASPSSSFVGPLK
LLNNFFGADFMFNLRREDECSNDNGEVGVSGRDYALVSGDMWLQAFKWHSDHKNEMKRVG
SFSAGYVDISDVYPIHLRLSALREANSLGVKISKKDNAAELFRRACRIFNTEAELLQIWD
FSGRTSQFFVNNSNSPPKDIQRQSDQEMLLELQIYGLSDASKSRDKRDEFSEPCGAVGSS
TSTSTTMNGSNGNNYRFPRTNSSTFSSSSVESGSLGLTGLQNLGNTCFMNSALQCLAHTP
KLVDYFHGDYNKEINHDNPLSMNGEIALAFGDLIRRLWAPGATSVQPRTFKSKLSRFAPQ
FSGFNQHDSQELLAFLLDGLHEDLNRVKLKPYVEAKDGDDRADEDVADEYWQNHLARNDS
IIVDICQGQYKSTLVCPVCKKVSIMFDPFMYLSLPLPSTSMRTMTLTVVDTNGYSLPTAV
TISVPKYGKGEDLIKVLTTACSLQTDETLLVAEIYNHRVIRFLEDLADSLSLIRDEDRLV
AYRLPKATEKDAIVVFMHQEIEEQYVHGKLTSGWKSFGIPLVARICNKISGSDIFNLFMK
LLNPFLMPNEDGLHDLDASESSLHDLDASESSAVDSIVGNTTNLIAVESCNDANVADASE
SSIVDSIIGNTTNLIAVESTNDAKAADGEGVNLVTGDEFLFYLMDDKGILSNSKLEMSDP
VISEDLPKRLNVVVSWPVKKTEIYDTVLLSQLPEIFKSGFLAKRPQENVSLYKCLEAFLK
EEPLGPEDMWYCPGCKQHRQASKKLDLWRLPEILVIHLKRFSYSRFTKNKLETYVDFPVH
DLDLSMYIAFKNSQASCRYELYAISNHYGSLGGGHYTAFVHHGGGRWYDFDDSIVRPINE
DMIKTSAAYVLFYRRVAES
>Sgl72775 E3_activity/RING/RING 27.8 10.2
MVIGGYEMTKMRKSFRESIKALEADIQYANSIASDHKREIDGACFQMRLSYSPAAHLFLF
LVQWTDCYLAGALGFLRILIYMTYEDGKTTMSVYEKKASIRQFYGVIFPSLQQLQPGITD
VEDKKQHEVCDLRYRRKDVYENNKSIEVEKEIEEECGICMEINNKVVLPNCSHSMCFKCY
KDWSARSKSCPFCRDCLNGVKSSDLWIYTDDCDTVALPVIMTENLNRLFIYLDKLPLVDP
YPGSATYDWHIG
>Sgl72780 E3_adaptor/Cullin_RING/DCX/DWD 62.9 5.2
MSPRTRRAASPKFVIERDEDSEVSSSDEEEVEDEDEENGVNNSEDDEVVEEDDEVEEKFE
DNKKTEKKPITISLKKVCKVCKKAGHQAGFQGATYVDCPMKPCFLCKMPGHTTMSCPHRI
ATEHGVVPAPHKSTRHSVYYVFERQLRPQVPAIKPGYIIPDHVRCAVIKYHSRRVTCLEF
HPTNNNILLSGDKKGQLGVWDYYKVYEKRLYSNIHSCLLNTMRFSSVNDGTIFGASSDGT
ISCTDLETGLSESMMDLNPNGWHGPKSWRMLYGLDINSEKGLVLVADNFGFLYMLDTRTK
GKVGEAVLIHKKGTKVVGLQCNPVQPDLLLSCGNDHFARLWDLRKLEAGASLGNLAHGRV
VNSAYFSPHTGSKILTTAQDNRIRVWDSVFVNMETPSREIVHSHDFNRHLTAFRAEWDPK
DTSESLVVIGRYISENYNGVALHPIDFIDVSTGQLVAEVVDPNITTISPVNKLHPRDDFL
ASGSSRSLFIWSPNDKSEDVQQRDKKKTIVFCGKGDKKHKSKLGDESDESDDELFKSKGK
TSKAKSITLKKVKR
>Sgl72790 E3_activity/RING/RING 18.9 13.1
MEEQAQITTPMLQPPINDDFAPSSSSSPSPALQLEESEQTEAYIEQDQQQQLNDMPWYWH
WQPNLVFERFNVTVCSDDVRNDAWSCLIMLLTFWFFASVVLILGLYGSFDLQLSPNCSFL
VETNPFFVHSIQARQLNDQTDGLMLYGFHESPALDVETTWSQNHTVPIEPTIHKEWAYYL
NAGSKVYVSYDVKYPDSSTLFLVIAQGRESLRNWIYAPSYNTTMSWNKIYGSGQIAQDIK
ESDTYFVAVGNLNLETVEVYLNITIKSFLYNTTKANFKCSLSNRVCDFGLIFLKPNAAVL
TSPGLSQVNSDINWYIQVSYEPQWITYCGGSCILAALIFALLRYCSNDNQTGNEVDERLA
VREPLLSPKNNDHTSWGSSYDSIPSDDDQDSDGKMILEGSCEGKVLKEGEIHSQTTRRLC
VICFDATRDCFFLPCGHCAACFSCGSRIAEEAGTCPICRRKMKKVRKIFAV
>Sgl72805 E3_activity/RING/U-box 74.4 0.2
MTSKQPPSPLETLNRQLELLVNSNDTFPFEPPRRFTSYAGDLHRITGNLLRLPNDVVLSS
PSIVTAVKGISVDLAKAYETVSVYKERSKIYVLINSRCLCQSLRERTVAIAGWLALLVTV
LHTFPDLRKKVYDLSRDMKLPHFALTENEDRVYCTLQKEGQGKPITRPVQSAIIMDLARA
LGISPDNHAELSEHVKLLKNDVARSNSVSERRILMSLQRILDSWFVEPNISALSLDFDLE
DDSQILPFKNFLCPLTKEVMKDPVVLESAQTYERTAIEYWFERCLEDGRDPTCPVTGKVL
SSLEQKPNIGLAGAIEEWINRNVDIQIKSAVKHLSMDPPPVDGLERVLDTIYKISEEHPS
SRYKIRNAGVVVLIIKVLKNFSKSTIYSLKTKALMALLSMAKDEDCKAIMIGEGITKLAI
NSLVAGSIEKEKEKENALMLLIELSNNEAYRARIASEKGAFLLLSSMAESLESPALSKLA
EDILKRLEVMDENVEHLAAAGRLEPLLSRLCEGSHGTQIEMASLLGKMTLTNSNKEHIAR
RCATVLVEMLLKLETRTASLHALCNLSSFDDNATVLVEASVLPVITDIVLESQDALPEQK
ELAAAIIANIVSNPGHWELAEVDKNGNSMLSSFIVSRLMQLLSQLTPQCHVYVLRILCGI
LSSPKSSEQVATEIKSGDGIKTIMEYLEHPETEHRIYALKLLRMLSESSGGVLFNEFKCQ
NKLVFLKEKLQDNMPTNSEQSDVACILANLPLSEEEVKTVLGPGFLNWTVMTLKENQRIP
SGRASRSSSSLLEGLLGLLLHFVRSIDAQILTWVKEHHLIVIFREQLIYLSQPRCKQLAV
VGLRHLSESGRSLASDGESDPLPPQGLCSSMVFICGRAIPDINSTCPIHNAPCEEESELC
LLKSYCIKPLVDLLSDDQTEVQIAAVEALSSLIPETSHNFRAAADELDRLGVVDAVANLF
IEIRPGELQEKAIWMVERLLRGENTSQRFAINQNLVSALGEALKLGNANTRKLAQDALTN
LKQLSGASGKISGPIRAWR
>Sgl72806 E3_activity/RING/RING 35.1 3.6
MDAEDLELSTISSDGFEVTSYAFEHASASNNHVHRPVDDLFNVMLCYEYNRIPNNVARYL
SFMMVKERDQSDRSDIVTDVINNLDEFDVDVNVYPCTIDVVQSSCEIFLKQVRDLGRRSL
AMIVKIIVFERMEEDLVGIAPDEEEQEPEPMMAEEEFEEEPMTGEHIALMVESTRRLKSL
EGIVIIVGNDGLDGVKVTRRDQFGTDMMGPCSICFKDFKDQENNGGESDDSKHNKTGLLV
LPCSHVFHNLCLLPWVYKGKGTCPNCRFNFLKNL
>Sgl72896 E3_adaptor/Cullin_RING/SCF/F-box 15.8 0.0
MANLPFELITSILTRLPVKSLVRFKCVSKEWNSLISNPHLIALHLTQSLSSNNRLLILNY
GTHLESTPLLLSSETEVKTRRFDLPSCFSGFEVSVCGSCNGLVALVCKKITVDNEYNDVV
LEVVLWNPSTNSHFVVPHAYENDDLLSTEFLGVSFGFGYDGAKDDYKIVRIVDYFHSNNS
STDDDDGNDNGDGVDEDVDGNGDEDDNDVDDGGDGNDDGGEDSDGEDHRCKYGFIFRDIM
VYSLRDNCWNKIHVAFFGDKMEWFCPGAVINNHLVHWIFWNYRKRKPILRGFNLSTFIWT
KLALPDFRGNNNGNHNKTDCPSDDDDNDDGDLFDHGFKPTDFVVLGVLDECLCLVTRICP
EFDNVYVWVMREYGVKESWTKLFDVAEASVVGPLLSTPLACCKGDDELLLRKHNEDGFCW
YDRKGKTVKAAPKLPSCNLKLHDVKLCVESLVPLANTTVDGSDDRRLNDANG
>Sgl72941 E3_adaptor/Cullin_RING/SCF/F-box 21.6 0.2
MSDLLPTIPCDIIFEILGRLPVKSLLCCKCVCKDWYNLINTSTFVDHHLKQSINDSDHLC
HRQRPFVFAWGKSLYLGEDIEFPKKLIKLNLFKDNNNNVIEFNDAHIIGLCNGLVCLRLG
SNPKHFLICNPLTRTFKVVVVAHGEWEEDMNRNLWYPVYGFGYDTKTDDYKIVVMTMGRD
RHIWIYSLKTNSWKKGCSDRLHQPPFQEKMYHNQLAYGIFGHGMLHCIVREVAIVSRDGY
TYQELPQISRFNLSSEDWDYDLSFPDHSSYDPSTHMKVDLRMLDGFFCIATYDFRENLYI
WIMKEYGVKKSWTKLHNCDLSIYNLIAFSRTRPNGLWFNISSQGGLVWYDPKQGTKELFE
YDIPFKNVFHYEVTLCAQSLVSAPGSSYLID
>Sgl72992 UBD/UBC-like/UBD_UBC 114.4 0.0
MASSPSQGSLLLQKQLKDLCKNPVDGFSAGLVNENNLFEWSVTILGPPDTLYEGGFFNAI
MKFPHNYPNSPPSVRFTSEIWHPNVYSDGNVCISILHPPGDDPNGYELSSERWTPVHTVE
SIMLSIISMLSSPNDESPANVEAAKEWREHRGEFWKKVSRCVRRSQEML
>Sgl72994 UBD/UBC-like/UBD_UBC 91.2 0.2
MSYKIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVTVIGPPDTLYEGGFFNAIMS
FPQNYPNSPPQVRFTSDIWHPNVYADGRVCISILHPPGDDPNGYELASERWSPVHTVESI
VLSIISMLSSPNDESPANVEAAKEWREDKEGFRKRVGRCVRKSQEML
>Sgl73002 E3_activity/RING/U-box 119.4 0.1
MEDNKEAQLLNKLIDRINEIASISDYRPPVKKQYCNLARRLKLLTPMFEEMKETSEPLID
DAFENLVAFGDSLNHALDLLRFGSSGSKIFLALEREPIMKNFDEVTSSLEQALDGISFEK
LEISDEVKEQVELVITQFRRAKGRVEAPDAELYEDVSSLYNSSNDTAMDPAVLRRVAEKL
HLMKIDDLTQESVALTEMISTADGDSDAKIEKMCNLLKKIKDFVQTENPDLGSSAGETNV
ASNCAGQTTADGSPKSLVIPDDFRCPISLELMRDPVIVSTGQTYERSCIEKWIGAGHNTC
PKTQQTLQNSSLTPNYVLRSLIAQWCEANGVELPKRPGSSNPNRSTSACSAAERSKIDEL
LRKLHSGNPEDLRSAAGEIRLLAKRNADNRVAIAEAGAIPLLVDLLSTLDSRTQEHAVTA
LLNLSICDDNKGSIINSGAVPGIVLVLKKGSMEARENAAATLFSLSVVDENKVTIGASGA
IPPLVMLLSEGTQRGKKDAATALFNLCIYQGNKGKAVRAGIVPTLMKLLTEPGGTMLDEA
LAILAILASHSEGKAAIGSADALPVLVDVIANGSPRNKENAAAVLVHLCSGDPNYLTTAQ
DLGIMSPLLEMTQTGTDRGKRKAQQLLERMNRLLEQQKQAQVQAEAEAQAPPPPPPPTAA
EE
>Sgl73014 E3_activity/RING/U-box 77 0.1
MREKPSENPKENPNDSNIQNQRSTKKMKRNINHIIFNDESTPMEEDGNAPIVQNNGEANT
HANSEPSTRVNPILNQEEAEKTTPKIMSFKDIIQGKNIPQISTPTDPISNPLFIANEEED
EDSDDDTLPEDYTEDARCPAILLSKDEKREMRKPWKFSLIVKMFDKNIGYMTLMRRLKKK
WQLKGEFVLTDIGCAYYIARFSNLDDYNHVLTEGPWMIEDHYLTVRKWVPNFIPDNSPIK
VLNAWVRIPSLAVEYFDSNFLKKVGAKIGKVIKIDKTTVAAERGQFTRLCVEIDLSKPLL
SKFWLKGRIWRIQYEGLRMICYHCGKISHKEEECPELHPQQEEEHAHEAPVNERVNVQSE
TSSVYGSWMMVTKPTRKRPTTRTKAQVGEKEQPPQELRSKNKEGAKNKEESGSRFNILED
NQEDQVEEVGKSTAEDIEVDNSPIAETPNLGNNSQEENIPKESDVDLEVIEQNNTQRYPT
VNLGSTSQKENIPNNNRKPEESKSVGKTFKKVKQSKPNKALQEVNPNTTPFIKPISQAIQ
KPTLKLPQNPPHQAINTPFSQPSHHAINSQPKHNPSIRNSSLIPHHDLILPPNFAETSST
RLDSAYTMADVEDVQPLVCDNGTGMVKAGFAGDDAPRAVFPSIVGRPRHTGVMVGMGQKD
AYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLN
PKANREKMTQIMFETFNAPAMYVAIQAVLSLYASGRTTGIVLDSGDGVSHTVPIYEGYAL
PHAILRLDLAGRDLTDHLMKILTERGYSFTTTAEREIVRDIKEKLAYIALDYEQELETAK
TSSAVEKNYELPDGQVITIGGERFRCPEVLFQPSMIGMEAAGIHETCYNSIMKCDVDIRK
DLYGNIVLSGGTTMFAGIADRMSKEITALAPSSMKIKVVAPPERKYSVWIGGSILASLST
FQQMWIAKAEYDESGPSIVHRKEAGKRRSRPRHKLELFENRSFFLMDEITFIGNNNPEDV
RWLCSLTDSELDLLISLKKLALQRAKSVGHESLAQKFDLKMLRALGYILMQLTTTQVNDL
QLTGLSKLDDFFDGCNLLKLDLEDRIEKGEQAKTEEKVNIEEQAKTTEQEDIGESATRSS
NVADTLKRKRNEVKIENVTLSSKVSLFPINHPRSLEPTTGVDAGNTPFQCSIMQLLTPLP
LPEPTFDRYSWSSSSSMASYGAELERLNSGLAHIHEDEDENERNQRLMMKKKNKVVYVAV
GRSMEKTVSLLQWAFRNFHNSEFCLVHVHRLSPFIPTLLGKLPATQASAEVVAQYRNEER
EKMRKILCSYMDICCKAKVKASSIITEDEEVHKGLINVVMKHGMQKLVMGSVPDNCFNVK
KSCRTANYAAKNAPLFCEIWFIHKGKHIWTKEASESVTLPTICQEDGPTTDRLRSKSFPY
NKSERLYSPINLQSRSSRPSIQYSGMKDMNQNEPSEEDLLLPSPVNPCNSGYGQSSISYD
SASCTSSMERGDSSDPDFRLEVENLHGQLLEAKAEVETAKAEAVLESLKRENLEAEAVKA
MKKVKDLECALNYETEQRKEAEDSLQSLVHKQERILQEKLQVSGEIQKTNTNVAVLENRV
QEANRRCNEADGELNLIRDSIPSLQKEKQKIERQIMEAERWLEKWRSRRQIGGTNCHGYV
GLLNDVPDLVEFSRSDLQTATCDFSDSFKLFEGGCGNVYKGELLNRTVVILRLHAHSIHT
THFQKEVQVLGKLRHPHLVTLIGACPEACSLVYDYMPNGSLQWHLFQKSNNAPLSWKIRT
RIISQISTALLFLHSSHPEKIIHGDLKLECILLDSDLHSKICDFGISRLLLQDTLHLPGI
RRYPEPLGAFPYRDPEFHRIGKLSPKSDIYSFGIIILQLLTGQPPVGLIANARRAVSGGN
LNSVLDSSAGEWEPFVAEKLAGIALSFCEQNSRDRPELTPSLVKELQQLHISKERTVPSF
FLCPIRQDIMCDPQVAADGFTYEGDAIRKWLENGRETSPMTNLSLDYLYLTPNNCLRQSI
QDWLCRY
>Sgl73022 E3_activity/RING/RING 35.9 4.2
MESWGKFLIFEATFIFVFVILPCCIEWFCNRNQDDSDSIAQSDALDVTLVYGATPEHELD
LEAGLKIENYETKIRKFDWNCSDRVICLDSLDNLQIVERDEVYHEDADVTTLRNCGHKFH
THCIKEWISKAHRTCPICRQRI
>Sgl73025 E3_activity/RING/RING 44.9 5.0
MDPQTYMYIDIAIAISMLVFASIFTKIIADVLVNARDDPALPRELIVEHEYDLEAAATVL
AKIDDKKIAEIAENCSDCAVCLDDFDDDDEEGNDNGIKVLRQCGHRFHSHCIQQWFSRGH
LNCPMCRNPVIKHVL
>Sgl73066 E3_activity/RING/RING 37.4 6.6
MSFVFRGSRGDIENGLSGIIPERRSVRIHPVRPVNSNSLAFLVTVLLLFTILNTHQMSPN
FLLWLVLGVFLIATSLRMYATCQQLQVQAQAHAAAASGLFGHTEFHLQMPPSIALASRGR
LQGLRLQLALLDREFDDLDYETLRALDADNVSNTSSMSEEEINALPVHKYKVTGPEGEDL
QPQEASSTSTSSEAKQEAHNGKSSEEGLTCTICLEQVKRGELLRTLPCLHQFHANCIDPW
LRQQGTCPVCKLKVGSEMQEVLDSNASNASDMV
>Sgl73121 ULD/UDP/UBQ/UBQ_PIM 53.5 0.5
MENKGSSVEEVKLQIKFGGQTISLFVSVDSTISDLKSLLQSSTNVLPRGQKLIHKGGILI
DSKTLRSSGITNGAKIMLMASQGLHQGEGPKLKDAPVVPNHRRVMNSDRMSSKPIQETPV
EKNRTERWKIMGVIGLSDHHLKAIPDEVWDCGSSVRVLDLSSNYIRDLPIKIGTLTSIQK
LILNANDISDDSINWQGLTELKCLTHLSLNQNHLTYLPSSVGAITSLEHLHVAGNKLESL
PTEIGLLTRLEILKVNNNRLSAIPTHIGDCSALIEVDISSNLLLELPESFGNLQKLMALH
LSNNGLKSLPSTLFEGCVRLSTLDLHGTEITMDMLREVKGWLEFDERRRMKYQRQLDFRA
GGSAEFDEGADKKN
>Sgl73122 E1 558.4 0.0
MLPRKRAVEGEVVDSTTTSSSSSSSAFKKTRVEGSSSAVNSVGNTSNNLNSNNNLSVGSD
DGVVTITMARGDGNPQDIDEDLHSRQLAVYGRETMRRLFGSNVLVSGMQGLGAEIAKNLV
LAGVKSVTLHDEGMVELWDLSSNFVFSEDDVGKNRALASVQKLQELNNAVLVSTLTTKLT
KEQLSDFQAVVFTDITLDQAIEFNDYCHSHQPPIAFIKTEVRGLFGSVFCDFGPEFTVVD
VDGEEPHTGIIASISNDNPALVSCVDDERLEFQDGDLVVFSEVHGMPELNDGKPRKIKNA
RPYSFTLEEDTTNYGMYQKGGIVTQVKQPKVLHFKPLREALSDPGDFLLSDFSKFDRPPL
LHLAFQALDKLVCELGRFPNPGSEEDAQKLISLANNINEDSGDNKLEDINPTLLRHFAFG
ARAVLNPMAAMFGGLVGQEVMKACSGKFHPLFQFFYFDSVESLPTEPLEPSDLAPRNSRY
DGQISVFGYKIQKKLEDAKVFVVGSGALGCEFLKNLAMMGVSCSSEGKLTVTDDDVIEKS
NLSRQFLFRDWNIGQAKSTVAATAATSINPQLCVEALQNRVGTETENVFNDSFWEDLSVV
INALDNVNARLYVDQRCLYFQKALLESGTLGAKCNTQMVIPHLTENYGASRDPPEKQAPM
CTVHSFPHNIDHCLTWARSEFEGLLEKTPAEVNAYLSNPGDYASAMKNAGDAQARDTLER
VLECLERERCKTFEDCIAWARLKFEDYFANRVKQLTYTFPEDAATSTGAPFWSAPKRFPH
PLPFSSSDTSHLHYIMAGSVLRAETYGIPIPDWATHPKKLAEAVDKVMVPDFQPRKDAKI
VTDEKATSLSSSSIDDGAVIDELISKLESIRSNLQPDFRMKPIQFEKDDDTNYHMDLIAA
LANMRARNYSIPEVDKLKAKFIAGRIIPAIATSTAMATGLVCLELYKVLDGGHKLEDYRN
TFANLALPLFSMAEPVPAKVFKHRDLSWTVWDRWVIKGNPTLRELIGWLKDKGLNAYSIS
CGSCLLFNSMFPRHKDRMDKKIVDLATDVAKVEIPPYRRHLDVVVACEDDDDNDIDIPLV
SVYFR
>Sgl73248 E3_adaptor/Cullin_RING/DCX/DWD 90.1 19.0
MTEKGKGGKSGKSGELTVDEKYSQWKSLVPILYDWLANHNLVWPSLSCRWGPLIEQATYK
SRQRLYLSEQTDGSVPNTLVIANVEVVKPRVAAAEHISQFNEEARSPFVKKFKTIIHPGE
VNRIRELPQNTNIVATHTDSPDVLIWDVENQPTRHAVLGAHSSRPDLILTGHQENAEFAL
AMCSCEPMVLSGGKDKLVVLWSIHDHVSTLATEPGSAKSNSAGTNIKSATKTGGDGNNGN
ADSPSVGARGIYKGHDDTVEDVQFCPTSAQQFCSVGDDSCLILWDSRIGLNPVAKVEKAH
DADLHCVDWNPHDENLILTGSADNSVHMFDRRNLTASGVGSPVHKFQGHNDPVLCVQWSP
HNRSIFGSSAEDGLLNIWDYEKVGKMQTESGSKVSEYPAGLFFRHAGHRDKVVDFHWNST
DPWTIVSVSDDCSSSAGGGTLQMWRIIDLLYRPEEEVIAELDKFRSHVTTCPPLT
>Sgl73276 E3_adaptor/Cullin_RING/DCX/DWD 17.7 0.0
MGEAEIENGNGKIDEVEDTQVKNPNNGGTLVEEEAAAEEIVGPVPPPQRRAKRPLQFEQA
YLDSLPCANMYEKSYMHRDVITHVAVSLADFFITGSYDGHLKFWKKKPTGIEFAKHFRAH
LGPIEGLAVSYFAFGISDCI
>Sgl73291 E3_adaptor/Cullin_RING/DCX/DWD 80.5 28.4
MIAEKPSWIRHEGMQIFSIDIQPGGLRLATGGGDHKVRIWNMKSVSKDSETDDQTHRILA
TLRDHFGSVNCVRWAKHARHIASGSDDQVILIHERKPGSGTTEFGSGEPPDVENWKVVMT
LRGHTADVVDLNWSPDDSMLASGSLDNTIHIWNMSNGICTAVLRGHSSLVKGVTWDPIGS
FIASQSDDKTVIIWRTTDWTLAHQTEGHWAKSLGSTFFRRLGWSPCGHFITTTHGFQKPR
HSAPVLERGEWAATFDFLGHNAPIIVVKFNHSMFKRNFSNAQDNKTSSAGWANGASKTGG
KEAQPYNVIAIGSQDRTITVWTTASPRPLFVAKHFFTQSVVDLSWSPDGYSLFACSLDGS
VASFHFEVKEIGQRLTDDELDELKRSRYGDVRGRQANLAESPAQLLLEAAAAKQNTSKKV
AVGVQKQQVASKPASDLGPISKVSDSHLDNGNKNGVSSDGLNKVAASARVSSPVKQKEYR
RPDGRKRIIPEPVGVPPQQENITAMSQNEVLDSSLAPSDVRKDVNPAQVRRIIGAGSDVK
ERSGVTAKASFSDSLVVEKVPVASGRDGGVLVESSASAKASSSLAACKTTLTIKVVDKKE
GSDAMPISLEARPREHAVSDIVGMSNMSLVKETEIVCSRGSETLWSDRISGKVSVLAGNA
NFWVVGFEDGCVQVYTKCGRRAMPTMMMGSSAVFVDCDECWKLLLVTKKGSLYLWDLFNR
SCLLQDSLASLITADPNASSKDAASIKIISAKLSKSGSPIVVLATRHAFLFDMSLKCWLR
VADDCFPASNFASSWNLGSSQSGELAALQVDVRKFLARKPGWSRVADDGMQTRSHLEAQL
ASALALKSPNEYRQCLLSYVRYLAREADESRLREVCESFLGPPTGMGGSASSDTNIAWDP
SILGLKKHKLLREDILPALASNRKVQRLLNEFMDLLSEYGSAETHTEQTSLISSMVATRA
TERIDMMPSLNDMQVDPPVVDPIMDLLPQKSKQGDATPSTRDHQMDGSTIPPDQVIKVGL
GEDRVTINPAKDDVNLIMTKDQANPLPWYTEPMNIDMPKTEKVVVALPAKDQNF
>Sgl73356 E3_activity/RING/RING 37.7 12.5
MDDFNMSPPTMSSAASKAVSISAQVMIIAIVILCVVIAFCLCLHLYVRYCWLHNTEDPNI
VSWRRRLARQQRPQSSAATHRRGLDAATLQSLPTVVYNPKDFKEGLECAVCLSELSEGEK
ARLLPKCNHGFHVECIDMWFQSHSTCPLCRNSVVSGDSNNNDHNDVEVQDNDDFYSSDSS
ESEYDHDNDSRRATELPVYPTNVLFWGNETQVRSFGQAADNDASSSAGSSSGVSRPRNTD
EVVIEIPSHHEFCEDCLSLPPPQEEPKTPVMTRLRSLKRLLSLGKRVGVAPLPHGSSSSS
CEVDQNHQQV
>Sgl73372 E2/UBC 95.6 0.0
MAEKACVKRLQKEFRALCKEPVSHIVARPSPNNILEWYYVLEGSEGTPFAGGYYYGRITF
PSEYPFKPPSIRMTTPSGRFMTDTKICLSMSDFHPESWNPMWSVSSILTGLLSFMMDKSP
TTGSVSTSVEDKQFLAKNSLAFNCKNPTFRKVFPEYVEKYQQQLAEQAHLDALALRAKEE
SSALKSETLGNNMQGNLAEAEGGNRRKNRKQPVPTWVLLLVFSIFGLVMSLPLLEH
>Sgl73390 E3_activity/RING/RING 11.1 26.3
MASSNIDLYVDETYLLTLLNDDEQLIPISDEKYAQELHLQEALHSSSSSSSSSSSSLTLF
AESSSFFPEIFECPKTEDDEKQSIEENRGKSKKQEDREVGESSKPQLNFCGICMDYKQNP
EIFKGLINCNHDFCTDCIIKYVASKIQENIAMVECPNPKCKQVIEAESCSSILPKEVFGR
WEEALCEAMILGSQKFYCPYKECSVLMVDDGEEVRESECPSCRRLFCAKCKVPWHAGVTC
EEFQNLEKNERANEDIMVMKLAKDKKWRRCSNCRIYVEKIDGCLHMTCSLGYTQQVNNNL
QFIAKMPSLVNRLVNFCV
>Sgl73392 E3_activity/RING/RING 24.5 3.1
MASSNIDLFVDEAYLLALINDEPLPISDEKYAEELHLQEALFNSSSLPRAPVFSYPRTED
EKHSIIQTREKGESSQTHPIFCGICMENKQNPKIFKGLTNCNHAFCNDCIVKYIASKIKE
NIAMVECPDPKCKQAIEPENCSTVLPKEVFGRWENALFEAMIPESQKFYCPYKDCSVLMI
DDGVEEVGMSECPSCRRLFCARCKVNWHDGVTCDEFQKLGENERAKEDIMLMKLAKGKQW
RRCPSCKIFVEKTEGCHHMKCRCRYDFCYHCGCGWSETHQSQCLS
>Sgl73464 E3_activity/RING/RING 36.5 7.8
MDTDVVMVPAGEGSSVGGPSSKKPKRFEIKKWNAVALWAWDIVVDNCAICRNHIMDLCIE
CQANQASATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNSEWEFQKYGH
>Sgl73476 E3_activity/RING/RING 13.7 12.3
MSAGDQAVAAIAAQVALAGDGALLGLALAYVAFRSFQKYAATSLALRKISDAPSVHVSDL
RSLITDESDGGDKDGGERVAKVLVVVRGLVESKSIGKGSWKSLWPDVIVSENSGVRGVVL
QRSQKCIYNEWRGLFGWYPDVRSILARAWREAGSTSLRSVPFVLIDDCRQQLQSDYVVVD
LDESNHPLPLTTVYQHMQPIQASPYTFLQALTGHEYPVGLLDVEKILPIGKEITAVGICS
SKNGVLEIKSCRDLPIFLSEWTKDQMVIELSSKTKILLWSGVIVGSVSIAVLGYAIVRNW
NKWKQWREQRRTQQENRAALSGEGGSSSSNEFEVAEEEEVEDVPEGQLCVICLMRRRRSA
FVPCGHLVCCQRCAFSVERDLAPKCPVCRQTIHGSVRIYDA
>Sgl73549 E3_activity/RING/RING 13.1 6.1
MQLALNDGLQEVSSETEPILSESLIVEESQETTLCEIKTGDGDISVVADVDADEYCTLVT
SEQPQCRICLDSEGEDLIAPCYCKGTQKYIHRSCLDNWRSTKEGFAFAHCTECRARFLLR
PNIPSDRWWLRLKFQFLVARDHVLIFIVVQLIVAMLGVLVYRYYGEELREMFGYRVHPYA
FYITAVLAIILIGMLYGFFIAIICGQRISERHYHVLAKQELTKEYIVEDRESRDVPELDP
CHESELRMLGLY
>Sgl73556 E3_adaptor/Cullin_RING/SCF/F-box 16.4 0.1
MEPQQQSSETSINNLVQDHLLSILLLLPINSIISFALTCKKFNSIASSNTLWESICSREW
GPTCVDALKSSYLASNYGGNQLPWMKLFQQVAQLNSVSCLKLSYPISDDSVPCPRASHSL
NYVSNCLVLFGGGCEGGRHLDDTWAAYLGYDYKTILKWQKVTSGLPSGRFGHTCFVTGDF
LILFGGINDHGIRQNDTWVGNIVLSETFGITLLWRLLDVGSAPAPSPRGAHAGCCMDNRR
MLIHGGIGPDGVRLGDLWILEMSENFRHGTWHEILTHPSPPPRSGHSLTYLDNRRTLLFG
GRGLGYDVLDDLWVFDASEGEDHPQWSRVQFDSSSTSWGSDLPRVGHSATLVIGGKLLIY
GGEDSLRRRKNDFWLLDVNSIKKHPLCSRMWQRLKSSGYKPKSRSFHAACSNHSGHLVYM
FGGMVDGILQPAEPSSLRFDGEVFAVDFCLNFR
>Sgl73562 E3_activity/RING/RING 13.1 6.1
MQLALNDGLQEVSSETEPILSESLIVEESQETTLCEIKTGDGDISVVADVDADEYCTLVT
SEQPQCRICLDSEGEDLIAPCYCKGTQKYIHRSCLDNWRSTKEGFAFAHCTECRARFLLR
PNIPSDRWWLRLKFQFLVARDHVLIFIVVQLIVAMLGVLVYRYYGEELREMFGYRVHPYA
FYITAVLAIILIGMLYGFFIAIICGQRISERHYHVLAKQELTKEYIVEDRESRDVPELDP
CHESELRMLGLY
>Sgl73567 E3_adaptor/Cullin_RING/SCF/F-box 15.2 0.0
MCNCVVGANIISGDLTLPSLPQIHFLLYQTANRDPMTNVIDFVTSYDNPFGKLPDHLLVD
IFIRIPVTDWAKVSCVKKQWANIFQGECLWQAALAKTYPFAGLAKRWPGPIPRGLSKRRF
TALYISRHILSVDDGMDEIVGHTYLFLKEQLEISTMPPPSTILHGTIIDQFIACGNSRER
AHELASLIWLAVIDNLEEDERTFHLLRRLAREGNVFLPFPYSRSNKVLWRIFEKLFTDFR
DCLNYADYCDLLASAKSRFQPIPSTWLGY
>Sgl73611 E3_activity/RING/RING 31.5 8.0
MAERHHQPSTSGVRTNSDFMDVDEVLVVPDTPDRVSRQTKNIRSVEFSSRSSGVASRVTR
DRMNRHFGDSARSAGMHSRGDVGVKAQIHDVNCTNVPSSSFSNAPMSSMAVGNTLTTHKD
IYHRNRQHLEDGKVSKSSSIKSSHHHKRSEDPVFVEFCEIAESPTSTRGNLGVRMRNKDD
LLPNRSSSLHTAGNFSKPNRSNYKEKDKVDYDNPVNCDTHSVKQNDNNCLGTSDNNTGKG
LFVPSHTFRIPRTRTTEKKRLVRNGCISPQNIANAKRLEETSGNGFENTECAVIAGGSHP
VTEVNEVTSKQSAASRAKGKGLLIHDSSSRGYAGRRSHAGYSTGERCKGKYPEKDCVSVQ
DTDVNSNKVVDKSTSSIPSSSFVQKPAVSEGQRQRKHGLSSGSPLKSTEVICLNSGAESS
TKKSVRDHGGFLQRELGSQLAFDEPCLEPIDSTSQADGNSDVMASQLLADEMLARELQEQ
LYNEIPESTSVERLSSLGLHLPEEQLGDSLQLASSRRNHQVHHFVGPPPSNRRQASQSHS
LRNRLFRRGTQARLPRSNVPRLRSHIHHQGRRRDRLFPSQMDLDMRMELLEALEAVVSDD
VRMVNQLLDSDREFGENDYEMLLALDENNHTHLGASAAQITNLPESTVNTDNSEVCSICL
ETPAIGDTMRHLPCLHKFHKDCIDPWLRRKRSCPVCKSDI
>Sgl73635 E3_adaptor/Cullin_RING/DCX/DWD 56.6 7.7
MNTPIIDPLQGDFPEVIEEYLEYGVMKCIAFNRRGTLLAAGCSNGNCVIWDFETRGIAKE
LQDKDCNAAITSVCWSKYGHRILVSAADRTLILWDVATGEKVAQTTLEKAPLHARLHPGS
STPSLCLACPVYSAPLIVDLKTGTITVLPASISDGGDGQSAPSRNKVTDDSAPQTPACFN
KHGDLVYLGNSKGEIFIIDHQTAQVRAVVSVAGGAVIKNIVFSRNGQYLLTNSSDRIIRV
YENMLPTKDSLKVLDEMSDTLNDLSGVEKLKVIGTKSLVLFREFQDSVTRIHWKAPGFSG
DGEWVIGGSASKGEHKIYIWDRAGHLVKFLEGPKEALIDLAWHPVHPVVVSVSLTGVIYI
WAKDYTENWSAFAPDFKELEENEEYVEREDEFDIMPETNKVKESEVNQDEEVDIITVELE
STFSDSDMSQEELCFLPAIPSPDAPEQQDKSAGNSLKLADSNHSASPLSAGAVQNGHAMN
HESSPVEGIDFSTTDDISGGRMKRRRKPSEKVLESQAEMVKKPVKKAKPSAKSALKPKDK
SLVDEDNGVSVSMDEVSDDYYR
>Sgl73677 UBD/UBC-like/UBD_UBC 247 0.0
MASKRILKELKDLQKDPPTSCSAGPVGEDMFHWQATIMGPAESPYAGGVFLVSIHFPPDY
PFKPPKVAFKTKVFHPNINSNGSICLDILKEQWSPALTISKVLLSICSLLTDPNPDDPLV
PEIAHMYKTDRPKYESTARSWTQKYAMG
>Sgl73687 E3_adaptor/Cullin_RING/SCF/F-box 13.1 0.1
MEFETDDTTFCKLSDDVVLKIFTLLEDDPRSWASLSCVCTKFNSLISSICCKSKCVASLS
SDLLSLSSSHGFPWSSLFKLSVCCPGLLHCGVLLDNSDFGLHREIGFHDTDSDLSLLSNS
FSSSSQAHNHQHRYDDRNDADDNSGSGNGESVDDDNDNKLFEGWSMYDDLYFDTMYDNSE
TSAAPVVVTTWADNLDTGFNHDFKRRKVDVTDEGEEDDHNVNDSSNDIDDRRRQQRSHLA
TGAWNLSREQGMKLLASRFRDDCLYISEWPGCVHGSEEEEEEDHNNKRKYMLFRGVFSDF
KKTRVWRTIKDGNHRSKIELNCAFCSCKETWDLHSAFCLKRGFGFHDDGEPVVRAYVCEN
GHVSGAWTDLPLYT
>Sgl73698 E3_activity/RING/RING 25.2 6.5
MLRSEDSDQAIDLNVEPESSVPCSICLDLVNCGGGRSIAKLKCGHEFHLDCIGSAFNMKG
VMQCPNCREIEKGRWLYASGSSNSSPEPGMDDGSVDNFPFYFTFSEMPYGVQICPFRGFT
QVHPSSQLLQHPSLHTSDSIHGPNHSHFHALPSQDDTFSSHASNAFEMPYPTWGFHLPIL
SAPRSQMNEEVGHASGPPVISGTGLGELDMFSESRSAYAISSNHRSSLGVMSSLTPMITH
QHPGAGSPHPHGWVQFQQTSYLHHHHQASGLPMPISSGVGRFDTQRSMPRFVPSGRVYDP
NPSFSHYAESSPVNYSPHAWSRDNVPHFPMP
>Sgl73704 E3_activity/RING/RING 32.4 8.5
MKFCKTYQEYMQNLESELPGVGLKNLKKILKKCRLDLESHNSSDNDDCPNHCPVCDGTFF
PSLLKEMSAVVGCFNDRAQKLLELHLARGFKKYYVWCKGKQDHISLIQEGQDLVTYAMIN
AIAVRKILKKYDKIHYSKQGQEFKSRAQSMHVEILQSPWLCELMAFHINLREKKANTKRG
ANLFEGCFLKFTDGKPSLTCDLFDSVKVDIDLTCSICLDTVFDPVALTCGHIFCHICACN
AASVTIVDGLRASSPKQKCPLCREAGVYESALPMVELNILLRRRCHEYWEARLQSERTER
IKQAKEHWEFQCRAFMGV
>Sgl73713 E3_adaptor/Cullin_RING/DCX/DWD 53.8 10.9
METAALMEVEEQQQPNSTPTSFNRFPLKNSIQTNFGDDYVFQITSKEDWSSMAVSLSNNL
VKLYSPSTGQYIGEFCGHSSTINEIAFVDPLSPHLLLSCSSDASIRAWDCRNLQQVSMIN
AGPSQEVFSFSYSGVNNLIAGGCKSQIPIWDWRNQKQVACLEESHVEDVTQVRFIPGTEN
KLLSASVDGLMCLFDTSGDINDDDHLYSVMNVGTSIGKIGFFGRNHEKLWCLTHIETLSV
WDWKEEKNVADFQEARKLTSENWVQDHVDYFIDCHCSTEDDRLWVIGGTNAGKIAYFPVN
YNGRIMSSPEAILEGGHAGIVRTIMPASGLRGRSSNRNMFGWTGGEDGRLCCWSSDETSD
VNRAWISSNLTVKPSKSRKKNRHQPY
>Sgl73728 E3_activity/RING/RING 35.5 2.9
MDGQLLSTSSINGVVVTSYAENVSNSNTIYVNRPVDRFFTVELCYQDYRNENPNETNLVF
KLEKECDLCEALETLNVDVTAYYWVIEVVTKSCEVLLEQVIVDGRKCLKMLVKIMIVEQE
EEATDVGVDVSSIVEVKAFLSAKGGVSFISGEQVGSNMGPCSICLDEFDQKPENNNDVND
PKPKDIALLPCSHVLHGDCLVPWIAKGKTTCPLCRFNVLPNECMIKLS
>Sgl73751 E3_activity/RING/RING 38.6 2.6
MEDEILSSLSTNGVVVTSYAVDHLVSASNTEDNCPVDDVFTVVLWYEDYRDPMGRNLVFA
LQKEGDPFDILPVVFDELQRLNVDGKAYDCAYDVINESCEVLLEQVVERGRKSLAMDVKI
MIVEEDEEEEDETMDVDMDEDDDVGVLDVSSSVEVKNFLSINGGVSFISGDRVSSNNMGP
CSICLEEFDQKQEHINVSSDGKPNNDVAVLPCSHVLHGDCLVPWIVKGKSTCPLCRFNLF
SYD
>Sgl73754 E3_adaptor/Cullin_RING/DCX/DWD 37.1 0.4
MATVSAWPNNPNPNSNPNLNPNPSSSPQPPYLTVDPNHQPQTPSSPPSPMSQQSEHLYFD
SNSNSDSQEQDSLTPPALPPIRTSLVENPNPSPNPDSPNSIASQPPNLLHVSFNQDYGCF
ASGTDRGFRIFNCDPFREIFRRDFDRGGGIGKVEMLYRCNILALVGGGPDPQYPINKVMI
WDDHQSRCIGELSFRSEVRGVRLRRDRIVVVLEQKVFVYNFADLKLLHQIETSPNPKGLC
EVSQSAGKLVLVCPGLRKGQVRVEQYISRKTKFIMAHDSRIACFALTQDGGLLATASSKG
TLVRIFNTFDGTLLQEVRRGADRAEIYSLAFSTTAQWLAVSSDKGTVHVFSLKVNSGTPV
NETTSPPPESNTSGAPAGSSLSFIKGVLPRYFNSEWSVAQFRLIEGNQYFVAFGHQKNTV
VILGMDGSFYRCKFDPAKGGEMIQLEYNNFLKPEEPF
>Sgl73788 E3_activity/RING/RING 14.5 7.1
MAGKKRSMSLDADVYGVQKEWDEALCPICMEHPHNAVLLLCTSHAKGCRSYICDTSYRHS
NCLDRFRKLNTDSRTSPQDNTPVSQNLQDSSLVSDPQLTSLFGNDLPVLHRANSSGNSFT
SSRRSGDSTDNVEQEAVERQNLEQDEFAKKSSLQCPLCRGDVLAWTVVEEARDHLNMKPR
CCTRDSCSFVGNYRELRRHARRDHPKVRPAEVEPSQQRAWSRFEHQREHDDIVSAIRSAM
PGAVVFGDYVVDYNDRTPVERERTSSDASGRLFTTLFLFQMLGSMHSLAGPRSRSRPWTR
HRRLSGGSSRQRYHWGENLLGLQDEGGDGDDSFTDDDEMNILNEAEQGTSSTTRQRRRLN
QSGFRRNRL
>Sgl73790 E3_adaptor/Cullin_RING/DCX/DWD 87.3 10.1
MAVVELETYPTNPRVKPASKKPNKSPESKYWKSFKTTEVKGLVSSITSIDFSPISPHHFA
ATHSASLSFFNPHHPFTPNEPISTTHAFKDISFSASYRSDGKLIAAGSQTGVIHVFEAKT
RNQLRQLKGHSRPVRLVQYPSFDKLHLFSGGDDSVVKFWDVSTETTLSNFIGHKDYVRCG
SSSPIDDNLFVSGSYDHTVRVWDVRSGSNNNNNNSALVINHGKPVEDVMFLPSGGLIATA
GGNVVKIWDVIGGGKCVHSLETHNKTVTSLCVGKVGRISGQESDQYRLMSVSLDGYLKVF
DYAKLKVTFSMRFPAPLLSVGFSPDCSTRVIGTSNGVIYMSKRKKVKVDEERRDGEFLGF
QYREEPRKRVLKPSFFRYFHRGQNEKPSGGEHLILRPKKVKLAEHDKLLKKFRHKDALVA
VLNKKNPDNTVAVIEELVARKKLFRCVSNLDIQELELLMVFLQKYTTLPRHAGLLMPFAS
KVIQMRAEDIQASDSLKSQLRNLKRTIQEELRIQQSLLELQGVISPLMRIAGRR
>Sgl73822 E3_adaptor/Cullin_RING/DCX/DWD 84.8 16.6
MAQSNWEADKMLDVYIHDYLLKRKLHNSAKAFMAEGKVATDPVAIDAPGGFLFEWWSVFW
DIFIARTNEKHSEAAAAYIETQQMKTREQQQQQQQQQQLQMQQLQLMQQRNAQMQRGGPN
HPPLGGPVNGIMDNRMALLKSASNSQGQLIQGNSGSMSAALQQIQARPHMTTDIKSEVNI
SGSQKSLPMDPSSIYGQAILQSKSGLGSAGLNPGINSLPLKGWPLTQGLDNLRMQNQKPL
IQNQILLAAQQQQVLSQAQTQNSFGSSPSYGDNDPRRFGGLPKGSLNTKEAQSARNDVCS
PMQSSSPQMKMGQMQQSSSQQQEQLQQQQLQQNNRKRKQHSSSGPANSTGTGNTVGPSPN
SPPSTHTPGDGIGPANSLQQANSMPKNLIMYGAEGTGALASSSNQLDDIEQFGDVGSLDD
NVESFLHDGGDGKDLYGTLNQSPVEPKAEPSKGFSFAEVDCIHTRNKVTSCHFSSDGKYL
ASVGHDKKAVLWNMDTRKQESTPEDHTLVITDVRFRPNTTHLATASFDGSVRLWDASNPS
YCMNVYPGRGTHVMSLDFHPKKNDLFCFCDSNNEIHYWSMSPFSCIRMSKGGTAQVRFQP
RVGQFLAAASDKVVSIFDVESDRTTQSFQAHSDVVTYICWDASGELLASVSQDSVKVWSL
ASGECIHELSSNGNQFHSCVFHPSFASLLVVGGTRSLELWNMADNRSMTVPAHDNIVSAL
AASVTGMVASAGHDCTVRLWK
>Sgl73823 E3_activity/RING/RING 15.4 14.9
MSSLNSSSSTSTTTMGNTPTIETQNQQEEDNEETIFDSFICCVCLDLLHKPIVLECGHVS
CFWCVHKSMDAVNVSHCPICRHPYHYFPTICEMLHFLLIKLYPLAYKKREAQIYKEEKAN
RCFSPQLDSKDLYISDDSKPSPAVNMSSDMASVSCITSNGSSTGEGNYSSATNIQRAFER
VSTSDVLCPSCKQLLFRPAVLNCGHVYCEACIVIPEDGIIICKVCEYPHPSDCPNVCLAI
NNFLEERFPKEYAARRENDERKRERFYHKSPSSCSGSKKSAKNICCIPPRHGEEFKPGSK
EHCPKIHPGAGCDYCGMYPIVGDRYRCLNCMEKMGFDLCGACYNTRSKRPGRFNQQHTSE
HRFELIQPRDASSNMMLRIVGGYLVNSSGEPVLAIGAIEDPHDGWVAVESLDENLDELDN
SEANDGSVDIEFSDAVEDSGDHDHNGRENPPF
>Sgl73842 E3_activity/RING/RING 13.8 13.8
MESDGGGVATAVTPRRLSNQHSTLRDTFIASDLADAINREFTINCTIDNSNTTSSRRESS
LTLGAVLNNEKKSPPPPNIVVRTLLEIIHNDETLSPRGSGGSPTGRRTWKSFKERLRLKK
HQNQSRNRNSNSQRWESSFPVPRSDVIPSSRSLSVGEMMANRNSLRSNSQRRIDTVPADD
LTLREVDSGGSPRSGGSFRLSAALAAEREQTRRRLSRELDEGNRLGEDGEESDGSPLGND
DDNQDENTDEDEGGIPDLGPPANQPMRMSLMDLLEETDRQAGISGPTYRLDDEEEEEEEE
EVEQEVEAEDAGKGEYSCCVCMVRHKGAAFIPCGHTFCRLCSRELFVQRGNCPLCNNFIL
EILDIF
>Sgl73849 ULD/UBL/SUMO 101.3 0.2
MTAENDAGNTASMEDKKPADQSTHINLKVKGQEGNEVFFRTKRTTALKKLMSAYCDRQSV
SMESIAFLFDGRRLRENQTPEELEMEDGDEIDAMLHQTGGYY
>Sgl73859 UBD/Alpha-Helix/UBA 29 0.0
MAAPEVDKRLLEELQEMGFSLGCATRALHYSGNTSLEDAIDWIVNHENDSDIDQIPLIPV
DIVLDAPKPFPISEGVKISAQRLSLRNESKQSRKEKESELEREREKERIQAWKRILEAKQ
IAEENARKRMIMLREADKEEERKARKIIRQKFEADKAERRAKLGMPSAPSLSTQPACHVD
NMVQEQSAEVSKPVKSTKKAELLSDCLRGLRRYHKDEDARVKKAFLTLQIYIRNVMNNPD
VEKYRNIRFSNPVFQERVGSLTGGIRFLELCGFERTNQAQFLRLPREKLDMETLTSAMSA
LQSAITNPFFGLLSAEQP
>Sgl73910 E3_activity/RING/PHD 36.2 24.1
MGRKKNLVIDDDEYSVAAELNEESDVKEDKVAATGGGKKKGKKGSSKGVKARDGEDESDK
GEEEEAAGKKKISKEVEVQKEKQSTDTQDKKSEVNLRSPICCIMGHVDTGKTKLLDCIRG
TNVQEGEAGGITQQIGATYFPAVNIRERTRELKADAKLNVPGLLVIDTPGHESFTNLRSQ
GSGLCDIAILVVDIMHGLEPQTLESLNLLKMRNTEFIVALNKVDRLYGWKTCRNAPIVKA
MKQQTKDVQNEFNMRLIQIITQFKEQGLNTELYYKNKEMGETFNIVPTSAISGEGIPDLL
FLLVQWSQKTMIEKLTFRNEVQVLGVNSGIKHKFNEGDRSENLKTESTPGKVQVVARILR
SRVVPANSSGEETVKRNSRVSIRKRNRGADDLGEEAVTVKDEHNKSDVGTDYMSDCGKRK
TFVELQNAQAIPGNEVVSRKLIRSSEKKGKRGRPKISRGHPEEDIVQFSKVEDDGLNDNS
ARSSKKKDGRGRPRKYERSFEDKKMVADNIENEKAIADSIEEKPGVVSNKSVKMPTSARD
HPEEDAAQVNEVKTCIVEDEDLNNKSVSSSKTKKGRGRPKKYVNGFAIERPVADKTESEP
GDARNQSVGRPTISKEHPEEEIAQASEVKVSKVGYEGSNNNSAELLKRKDGRGRPRKYAS
CFENEKAVPDKTDSVHGDVGKKSVGRRNNFRDHPEKDVAQMNKLNAVKVEDEVLNNQSAR
SSKAKGRRTSLRGKMEKVIKNEKVVNKIENTPESVKNKSVRSLTPTRKSGRQKRSVDYSE
VGAVRKRRKFSYCRLDDDDDDDIMNEDEETGLTSKVVKKSKKKGKRGRPKKELGNGEVEI
QCDDKDKVKKDDMKMKVSRNRKDICPHIEPEKVGIRSCKKVKFAGLKKDTIEGSEGEENP
LPEKKLPVKRKRVETAGSLSSEKNLIRQQIVDMLLSAGWTVEYRPRFGREYNDSVYVNRE
GKTHWSVTKAYYSLLQEVEESKAGDPNFTFTPLPEELLSKLFRVVSKTRSDKNKKKKDKD
NGDTSDEEVTGDKRRKRKPSVRVGTQGRRRCALVVRRSNQGSNTDIDGAITHTGKHSVLA
WMIDLGTISLNGTVYYKNCPEAESSFEGSITRDGVYCFCCKEIISVSEFEVHAGSKLCRS
YENVYLENGSSLLQSVLDSWNKQKEAGRLGFHGVNVDDDDPNDDTCAICGDGGDLMCCDG
CPSTFHLGCLRMEELPLGEWHCVYCSCKVCGVGGESETQGADCDTVSSQLVACRLCEEKY
HKSCTREDDVVLTESRRPEFCGKNCEQIYEKLECLLGTKCDLGDGFSCTLLQRSDLKADS
VTLEAQKIQDNSKLAVALAVMEECFLPIIDPRSGVSLIRHVVYSCGSNFNRLNFSNFLTI
VLEKGDEVISAASIRIHGKQLAEMPFVGTRNVYRRQGMCRRLLTGIEQALSSLEIENLVI
PAIPELMDTWTSVFGFKPLEEPVREEMRSMNMLVFAHTDMLQKPIVEKQLCAKRTSLIGA
EKDANSGVSQNDNLDGGADKIGADKLEIDNGTLNGKIDLNCVAPNNPDTLSDERRVVHPD
SDAENCEDEVKSIVNSGHLKDTKNDGGPCSNSSEVRTLHPDLNLMAENDSLSDDHAMKSD
VVAKSTSNSSGLTNVKGCCVVESDNDQNGDSNAVTSSEKRSLNPDLNLEGNVLENHDNLP
SNSASICGATESGDPLSRLDGRTPADQETQRDDKLLEVCRVEEIQCSDTETSKTHDVGPC
NDSISAPLLEVCRVEEIQCSDTETSKTHDVGPCNDSISAPLLEVCRVEEIPCSDTETSKT
HDVGLCNDVVPAMSVECSESEALMCSRTVQLTSESSSNMRSITGESCVAGVFPGSGITKE
GGKSNSLYRLLTIFKTLRTASSKYFCETERSGSSSLSE
>Sgl73932 E3_activity/RING/U-box 106.4 0.3
MAKTGVVSEGDSIRVLELKKELRLLMKAITDEEDNQIHTNNHHNNNDFVSNSSSSSFFDT
IDKAKDLLSALQDVKLKRTTSLRLDDGTLSCPPEFLCPLSKQLMKDPVIISTGQTYDRDF
IQKWLKAGHRVCPITQQVLSHSLLTPNYLVRKMISQWCETRGIQIPDQVGYINEEGASEN
DRDYFSSLIDKMSKSIGEQKAAAKELRLLTKRMPSYRALFGESTEAIPRLLRPLTQRRGS
FSSRSNDSISNECHPDLLEDLITTLLNISIHDSNKKLVAETPMVIKLLIDALRCGTPESR
SNAAAALFTLSAVDSNKVLIGKAGALKPLIDLLEEGHAMAVKDAASAIFNLCIIQENKAR
AVREGAVRVVLKKIKNGVHVDELLAILAMLSTHQRAVEDLSELGAVPSLLSIMRESSCAR
NKENCVAILYTLCINDRSKLREVQEEERAYGTLSQLAQDGTSRAKRKASGILDRLHRAYN
LTHTA
>Sgl73933 E3_activity/RING/U-box 91 0.0
MSPMAAMSSVAKQAEQLRQDGNNYFKKDRFGAAIDAYTEAITLCPNVPVYLTNRALCYRK
KNNWARVEEDCRKAIQLDNSSVKAHYMLGLALLQKQEYSEGVKELDKALDLGRGANPKGY
MVEEIWQELSKAKYLLWEHESSQRSWELQTLKEACEEALKEKHLMDSSKTKEFIDEAADD
HVKQQLKALKLIFGKAAEPDSPTEVPDYLCCRITLDIFRDPVITPSGVTYERAVILEHLE
KVGKFDPITREPLELSQLIPNLALKEAVQAYLNTHGWAYRMD
>Sgl73937 E3_activity/RING/U-box 106.8 0.3
MAKTGVVSEGDSIRVLELKKELRLLMKAITDEEDNQIHTNNHHNNNDFVSNSSSSSFFDT
IDKAKDLLSALQDVKLKRTTSLRLDDGTLSCPPEFLCPLSKQLMKDPVIISTGQTYDRDF
IQKWLKAGHRVCPITQQVLSHSLLTPNYLVRKMISQWCETRGIQIPDQVGYINEEGASEN
DRDYFSSLIDKMSKSIGEQKAAAKELRLLTKRMPSYRALFGESTEAIPRLLRPLTQRRGS
FSSRSNDSISNECHPDLLEDLITTLLNISIHDSNKKLVAETPMVITLLIDALRCGTPESR
SNAAAALFTLSAVDSNKVLIGKAGALKPLIDLLEEGHAMAVKDAASAIFNLCIIQENKAR
AVREGAVRVVLKKIKNGVHVDELLAILAMLSTHQRAWKICPS
>Sgl73940 E3_activity/RING/U-box 91 0.0
MSPMAAMSSVAKQAEQLRQDGNNYFKKDRFGAAIDAYTEAITLCPNVPVYLTNRALCYRK
KNNWARVEEDCRKAIQLDNSSVKAHYMLGLALLQKQEYSEGVKELDKALDLGRGANPKGY
MVEEIWQELSKAKYLLWEHESSQRSWELQTLKEACEEALKEKHLMDSSKTKEFIDEAADD
HVKQQLKALKLIFGKAAEPDSPTEVPDYLCCRITLDIFRDPVITPSGVTYERAVILEHLE
KVGKFDPITREPLELSQLIPNLALKEAVQAYLNTHGWAYRMD
>Sgl73969 ULD/UDP/UBQ/UBQ_PIM 138.9 6.0
MLIFVKTLQGKTITLEVESTDTIEGVKSKIQEKVIDENVQRLMFAGRQLEDGKTLEYYNI
QKESTIHVVLRLPLRCGRIIKVKTPNGKEIEIKFEPTDTIDRIKERIEEKDGIPPAHQML
IYAGKQLADEYDKTAKDYGIEAGSVLHLIVNRRVIKPLSPPPVKRSVVSKKRSASASSGK
PIKRTFSRVNSSSETQEPNSVSTMATGSKKTIISVPSAADLLKHAQAKRSPSGSTPFSQP
APKAVATPSNQLQINLPASFCDFSGTSSMVSELGQLHFPAARNYLEDFTTASILNDSVAY
CIQSLQGILTAKERLLALEAKVEALTNSEKALKERIRSDGAVIADLKKKNKELSDDAKKM
MKSEIYDVAGYYVYRTKSELMKEFLDGNTSHWTPEEDIKHFNDYFSNVIPPGVDDGTDMD
>Sgl73997 E3_adaptor/Cullin_RING/DCX/DWD 90.9 19.1
MASEIDNTSSFGSTSSSSSSIISNNSTTTNYLLSDFININTQQINPSFSVPHPYYNCIAT
LKTPNHHHITCLAIHNNLLYAATGNQITTFDLTTLSPIPSFDAQDLSSGGFIKSIVFVDD
HKILTAHQDSKIRAWKDQQPQGPQHRLITALPTMKDKLRRFIRRSNYVKVRRNKTKLWIE
HNDAVSGLAVNVNDGVSVIYSVSWDKTLKVWRGSDFKCLESITAHEDAVNAVTVSGDGTV
YTGSADGTIKVWKNKNDNNNSNNDKVWRHSMVSTMEKHRSTVNALALSSDGKVLLSGGCD
GMIIAWEKDDDDDDRMVENGVVGGHDGAVLALIRLDDDHDLFVSGGADRTVRIWGRVGKG
YGGGGGGEKRGLLFCCMGVLEGHDKPVRSLVVVPPRSEGGSDGVVRVCSGSLDGEIRVWE
IMVSELIINHRPSCNKDY
>Sgl74002 E3_adaptor/Cullin_RING/DCX/DWD 111.2 26.1
MSIKMSNEEVSILAIKQALKALRKRHLAEEGAHTAAIAAISRPLIYQGSEWKEKGEKLEL
ELQQCYKAQSRLSEQLVVEVAEGRSAKALIQEKETAVDNLEKEVAQLSDECSELKKLLDE
KTKGFELLTSENEELKKQLEETSVKAKNAEAENKMLVDRWMLQKMQDAERINEANALYEH
MVDQLKSSSLQQIALQQVDGVVRQSEEGAEFFVESSIPTTCKNRFHAHDGGCASILFEFN
SDKLVTGGQDRSIKIWDTSTGALTRTLYGSLGSVLDLATTHDNKTIIAASSTNNLYVWDV
NSGRIQHTLTGHTDKVCAVDVSKISNRHVVSAAYDRTIKVWDLQKGYCTNTIIFPSNCNA
ICFSTDGRTICSGHVDGNLRLWDIQTGKLLSEVAAHSLAVTSISLSRNGNTILTSGRDNV
HNLFDMRTLEVYGTLRGSGNRVASNWSRSCISADDSYVAAGSADGSVHIWSIQKGDVVST
LKEHESPVLCCAWSGLGKPLATSDKNGVVCTWM
>Sgl74005 E3_adaptor/Cullin_RING/BCR/BTB 23.8 0.0
MSPMETSDKLTGKPITTGNLPEYDVNVITSGGLRIPSHSHILAMASPVLEKFVEKPKRNR
KTGEKAIPILGVPCDAVSTFIRFLYSYRCTDEEMEKYGIHLLALSHVFSVPQLKQRCTKG
LAESLMVDNVIDVLQLARLCDAPDLYLKGMKLTASKFKSVEKTEAWKFVQKYDPWLELEI
LQFIEETELRKRRTKKHKEEQNLYIQLSEAMDCLVHICTEGCTIVGPYDMEPSKKKEPCR
RFSTCHGLQLLIKHFATCKKRVNGGCSRCKRMWQLLKLHASMCEQPGHCRVPLCRQFKLK
MQHEKKLDDAKWRLLVRKVVSAKTISSLSLSKPQRNTEMGKHFHASNLKGGCIQCP
>Sgl74024 E3_activity/RING/RING 16.5 17.0
MVGYQLVSSSTSHESLKVIEADIQHANMLAASIPRNKSGNWLQMKLVHNDLAPLIFYLLQ
WFDCSCTCLLPSCLNLFYVVIYKVNADGRPDMMSYGRRATLKEFYAIILPYLHRLHGSMS
ELNDGANSSNSSDLAIRKIAQESRQLSDIDFDREDECGICLEPCTKVVLPNCCHSMCINC
YRDWNLRSESCPFCRGNIKRVQSGDLWVLTCGTDVVDPKTVLKEDVLRLYLYINSLPKDV
PDALFLMYSEYLI
>Sgl74130 E3_adaptor/Cullin_RING/DCX/DWD 64.3 10.3
METVTRRVAQRQNRVSSFTWHRQPSNGSSPSSKDKVCSFWLAGNCRRKQCRYLHPEVTAP
IKRVYKLNRSSFKRSQESEKPLSANCKRENVNCISEYKRNQKISSKNEEGSDPAKIRKYD
HLCQASNATSGDGRNTPRTKICQHWIKDSCVHGDQCKDLHSWCYGDGISLVAQLEGHKKA
VTGITLPSNSDKLFSGSKDGTVRAWNCHTGKCIGVADVGVPVECLISDGPCVFAGVTDAI
KVWNIQLNTEFTLSGPAGQVYAMVAIDGLLFAGVHDGSILVWKFNSGATSFEAVAPLKGH
TDAVVSLIYGAKRLYSGSMDKTIKVWDVETMRCIHTLAKHSEVVMSVLCW
>Sgl74131 E3_adaptor/Cullin_RING/SCF/F-box 19.3 0.0
MAGNERRRMESLSEAIRDDNTCVDKQHTQFLPSWSDLPPELLELILSHLTLRENIRFSAV
CKSWNSVAVSVRPLPLHEPLWLSFNWAIW
>Sgl74208 E3_activity/RING/RING 18.7 10.7
MAESQAQAHFLNPWVLNLEKLGLELKCSLCLKVYNKPTLLPCDHIFCSSCIPKSNLFGSE
CPLCKISIAEKDLRQAPFIANIVNIYKCLDASFSTHMLSSDFSRGSVQCPYPNQRAKNRI
DSSTPGNSISGTCENVQHEAVDVDMNQMESPESPPSSGVSKGDTTGKCLSKKSAKRTCDD
FGAEGFGKSHDLCSKKQKQISQGVPEMNNTPSNSTDQHAAELDPASLCNFLCVFCQTWKV
TEGSGPMQHFVNGRQVFGSEASHSYVAHVHQSCIEWAPQIYYENDTTMKNLDKELARASK
LKCTTCGLKGAALGCFAKSCRRTYHVPCAYEIPECRWDMTEFLMLCPAHASQKFPSERSK
KAYVKKCSAVQIYNEQQSVSDFNFWATSLTGAKNWVLCGSALSADEKYKLVKFANLCGAT
VAKTWNPTVTHVIAATDTNGACSRTMKVLMAILNGRWILKTDWIEACMLVNSPVDEEPYE
ISLDNHGCSGAPKTGRLRVLNNEPKLFSSLKFFFTGDFVAAYKQDLQNLIIAAGGTILES
KVQLQQSSNELCHPSTTIIVYNDDSTGETNDNLLRQYTAERQALETGSQVIAHTWILDSI
ASGVLKPFAQRFAPKIPVDV
>Sgl74242 E3_adaptor/Cullin_RING/DCX/DWD 29.2 0.2
MIVEPIYHEIECEIFKQTGDNCACLRRCLHFHVDGLTWSNTIRRSICSWYIGIICIGAVN
AILLLDIFLFPRKTLMFDFFIPVPAILLGIFLVGKDVLRIFEGTCVVRKEISLGRPGIAG
TSIRSDGKIAATAGWDRRVRIYNYQKGNDLAILKYHSAMCNAVSFSRNCKLLASSSEDTT
IALWELYPPRNTTGASSSKPIGTRGSTHLPCEELAAVVEEWWWRCRVVAVRGGEGGKDAW
PELLGKKAKVAKVIIEKENHHVKAILVKKGNFVTQDYRCDRVWVWYDAQGIVFRVPIIG
>Sgl74287 ULD/UDP/UBQ/UBQ_Other 36.9 0.1
MVGYSPAAHEPLLENVFVRKAFSVDHLLTLLDMSKEIITEKINSPRPVRLLLVDSVTNFF
SRASFFDKAGLKERRKEMQKIASKMKHLASQFNIAVVVTNEIRDVVSGQSSTQASPPLPQ
LVSSGRLVKPALGYDWSELVDSRVFLTKIVDIQGVRSRFAVKVSNPRKNQPENNSVASLA
LQKYATEKEVKVDDLTLQLRRRFVHPDSTPAENNMQHGDILTVMHKTGQLLSWDLLSDSR
DYRLCTLQDLCTETFVTDMRVHLDDPVKVVRKQWEEITGVSWKNIMVYYDGKLIRAKTTF
RDIGLKDGDAIFMVGKTVFTKIGTV
>Sgl74343 E3_adaptor/Cullin_RING/DCX/DWD 43.2 1.8
MEDEAEIYDGIRAQFPATFGKKSKPQTSLESLHNTTLRTTTTTTTQKQQFNPSSSSSDSF
PSLSSSSKSWIDSVRPNPKSKLHESDGPPVVAEEDDGPSIGPPRPPAGFTVDDDDNDNEM
IGPPRPIPEEDEDEEEEEEEESRFRIPLSNEIVLKGHTKVVSALAVDHTGSRVLSGSYDY
SVRMYDFQGMKRDLGSFRQLEPFDGHQVRALSWSPTAGFFLCVTGCAQAKIYDRDGLTIG
EFVKGDMYIRDLKNTKGHITGLTCGEWHPNKKETILTSSEDGSLRIWDVNDFKSQKQV
>Sgl74394 E3_adaptor/Cullin_RING/DCX/DWD 73.1 13.1
MEDEAEIYDGIRAQFPATFGKKSKPQTSLESLHNTTLRTTTTTTTTQKQQFNPSSSSSDS
FPSLSSSSKSWIDSVRPNPKSKLYESDGPPVVAEEDDGPSIGPPRPPAGFTVDDDDNDNE
MIGPPRPIPEEDEDEEEEEEEESRFRIPLSNEIVLKGHTKVVSALAVDHTGSRVLSGSYD
YSVRMYDFQGMKRDLGSFRQLEPFDGHQVRALSWSPTAGFFLCVTGCAQAKIYDRDGLTI
GEFVKGDMYIRDLKNTKGHITGLTCGEWHPNKKETILTSSEDGSLRIWDVNDFKSQKQVI
KPKLAKPGRVPVTTCAWERDGKSIAGGIGDGSIQIWNLKPGWGSRPDIHVEQAHSDDITG
LKFSCDGRHLLSRSFDCTLKVWDLRQMKRSLKVFDELPNHYAQTNVSFSPDEQLILTGTS
VERDSPTGGLLCFYDREKLELVSKVGISPTCSVVQCAWHPRLNQVFATAGNKSQGGTHVL
YDPTMSERGALVCVARAPRMKSVDDFEVQPVIHNPHALPLFRDQPSRKRQREKILKDPIK
SHKPELPMSGPGHGGRTGTSSGSLLTQYLLKQGGMLKETWMDEDPREAILKYADAAEKDP
KFIAPAYAETQPKPVFEDSDKEDEE
>Sgl74438 DUB/USP 226.2 2.9
MKKLDLPVFDGDNPDGWILRAERFFHFYRLGEEDKLEAAIVALDGDALLLFQWEHRRRPI
TKWEDLKRLLLHQFRSTASGTLQEQWLDHKQTSGVLEYRRRFIELVAPLEGIPESLAKSH
YINGLKGDIRAEVRLLSPTTLDSAMDLSIKVEEKLKSKTQSFGPKHEPKPSSSLNSWKTN
HISPNPNFTKNPQGPNTFSSPQNRYNPNRNQPNKPTGEIRRLTEKEIQQKREKGLCFRCD
DKWSLNHRCHVAGFCALCAMQKHVNCALKSTGRSLAPKDLVSNLRRISRTFRNARQEDAH
EYMIHLLESMHKCCLPSGVPAESAGAYDKSLVHKIFGGRLRSQVKCLQCSHCSNTFDPFL
DLSLEILKADSVHKALMNFTAAEQLDGGERQYKCEKCKQKVRALKQLTVSKAPYVLTIHL
KRFRHFSGQKIDKKVSFGSTLNLKQFVSGAYDGDLTYTLYGVLVHAGWSTHSGHYYCFVR
TSSGIWYSLDDNRVYEVSEKKVMDQKAYMLFYVQDRKNVGTKKAMDAAHKENLFSTMRNA
SSPCSIPGVKSFQNGYFDKKAQEVIPSNQVTKQSEGHNASERLVEQKNSKCVPTNAIAMD
NELNQKTSSTKENPPITNTILNGMVNAATKLGDDNQSEKSAKATASSCPDNNREKDVASI
EKPSVSNCSFSVAIVPHSNDSQMAGTPTNIRNSLSNDSKPIIPSDSVIQPTTTFSTIKDG
ASEPVSDNCSVLSKPSVKRSRGSSLAKSSESTPHQRLMKDFLKSRVGGYLSTKMLYGASL
TLRKNKKFKRMKKRLKSVMQEKLLTEKSDPADMGPSTSGSDPLGNFKHSLKEGHNTCDSV
GENLGPRKDFNDSWSKEPNPHLVNGDSVATRGLKDSAGDILGANYKDFKNSCSKEPNSQL
VNGNSATTGGLKESAVGRWDGIEPPVKNVEPNGGRDTLTIGHVLDEWDEEYDRGKRKKVR
VSRNSFGGPNVFQEVALKKAKLKMEVFSVSSCCGIERCYNNFNNSRDYNTQQGFNQQNQG
YGGQGGGQWNKQGQGGNQWNQGYGGSQWNNNNSQNYNRGGLSDQEKFIPLHQRQNQPRPM
GNPPPSSQQFQRQPHEQHQNPNSQILLQTIQRMEQESKEERNAMKAHMKMLETQITQLAI
PKDKGQGKTSSVSSTSTQDVEHVNRIELRSGKTYDGPKGSDSKQDESALGGEMLRETLEM
KFCEMIKGLHINVPFLDAVQQIPSYTKFLKNILAKKRKPSEEVIQVPYQVSAYIDKKLPK
KLGDPGSFCLPVKIGDLEPRGALADLGESVSFMPLFIAKLLNFPLLPTRKTIQLADRSVR
CPSGELEDVPIQIGHVIVVYAKICLR
>Sgl74450 E3_adaptor/Cullin_RING/SCF/F-box 16.6 1.0
MPRTRSSAAASSVPEKPTLPEKEKVDLDVDNDPEETIEEEVEYEEVEEEVEEEVEEEEEV
EEVEEVEVEEEEEEEEDEEDEEEDDEEEADTTQNVGDADTDMKEGDDNKKHAELLALPPH
GSEVYLGGIPLDATEADLKGFCESIGEVIEVRIMKGKEPGENKGYAFVMFKTKDLATKAM
ENLNNTELKDTGQVLECSLAKPQADQKSPSGANTHKSTMLPGFGPRVGYNMVGGAYGAVG
AGFGSPGLAQPLLYGGRGPSSAGMAMMPMLLPDGRIGYATPGVQQHQHTLHSNIEVVEVV
AGVAPPVGEDVVMTVVGGEIVTTLTERNKRRRIKSLSAAIRDDNTCVDKLHKHTQFLPSW
SDLPPELLELILSHLTLRENIRFSAVCKSWNSVAVSVRLVNQPPWIMTVDTTLASNSMTG
ESRIRLRAYGLNRPRTYLFSCDASPIL
>Sgl74465 ULD/UDP/UBQ/UBQ_PIM 101.4 0.4
MQIFVKTLTGKTVTLEVESSDTVNNVKAKIQDKEGIPPDQQRLIFAGKQLEDDRTLADYN
IQKESTIHLVLRLRGGGSGTLSYPPTLLALARQYNQNKLICRKCYARLPFRSTNCRKKKC
GHSNQLRPKKMLQASGLGR
>Sgl74531 E3_adaptor/Cullin_RING/SCF/F-box 17 0.0
MLSLRTKNLTMDNNNDTQNHLPEELLFYEIFLCLPIKSLLICNCVCKKWNSIISNPEFAS
LHLKKSPFSNDQSLLINTKTGFLSFDLENFGVEAITETTADSVVASCNGLVCLDDEATNS
LYIWNPITSKKIRIPYPQPLVTTQVVWGLGYVSSTEDYKLIRIYNENFDQKVQIFSFHNN
TWKNSDIECEMCSFEELPPINGSGVSVNGMIYWATYYTEYDVGFYDHCFNILGFDVMKEK
FMPLTPVPEWSDRGFEQNSVLFLSNGCLCACWRTDEGDIDIGMLREEEAGKQSWVKHFHF
DHGSLLYDRKISFQKIQGVTKAGKYAVHVDGEHIILLDSNQDSSKEVQLKIPRARNVIGY
LKSLLSPSNMVNYKN
>Sgl74533 E3_adaptor/Cullin_RING/SCF/F-box 13.5 1.0
MENFSANLDDGELWIPSDIFPKDELHHHDCHNNRSIRDDDSLLEDLSRQLCNLKSNDLFL
TPNVSHLSKEFGGYSGAMTQNSSATTLAPAPAPAPTPTQNGCSDLKVGPKRVDDRGRPIN
NQPGPVHRLPALPFPMPQPTNPTVGQPLKETKTGNKSRKGYRHQQKHNWVFPTQQGRRGV
GFRFGLMNSNNASSGTGVFIPRPNSDSFETTEVKPQWMPTTKVGTKKDDDEFRHNTPPEV
GLPKDWTY
>Sgl74546 E3_adaptor/Cullin_RING/SCF/F-box 12.5 0.0
MKKQRTTMAETPSSSSSLSLASANVFDLLSEEIVFIILDYLHDNNPQDRKAFSLVCKSFY
SIESKHRRTVKPLRAEHLPAVLNRYPQISTLDLTLCPRITDFSLSIIASNCAKTLRSIDL
SRCKFFTGSGLEILVASCRNLVALDLTNATELRDSAAAAIGEAKNLEKLWLGRCKLITDI
GIGCIAVGCPKLKLIGLKWCLGIGDLGVELVAVKCKDLLSLDLSYLPGLMTFVAYAFCGI
TSKCLPAILKLQYLEELILEGCFGIDDDSLTLLKQGSKSLKTLDMSSCQNVSDTGLSLLT
SGTGCLRQLTLAYGSPVTLDLARSLQRLSKLQSIKLDGCLVTCSGLQAIGNYCASLRELS
LSKCSGVTDDGLSSLVKKQKDLRKLDITCCRKLTCVSIAHIAYSCTSLTSLRMESCTLVP
REAFVLIGRKCHQLEELDLTDNEIDDEGLKYISKCSRLSILKLGICLNITDVGLSHIGNR
CSKLVELDLYRSMEITDSGITAIARGCPGLEMLNISYCNSITDASLISSSKCARLNTLEC
RGCPLITSLGIAAIAVGCKHLTMLDIKKCYNINDFGVLPLAHFSQNLKEINMSCTSITDV
GLLSLASISCLQSMIILHLKGLTPRGLAAALLACGGLTKVKLHSSFKTLLPRPLFEHLEA
RGCVFQWREKMFQDELEDSKSWKMQVAELNNDS
>Sgl74569 E3_adaptor/Cullin_RING/SCF/F-box 16.5 0.0
MDNNNDTQNHLPEELLFYEIFLCLPIKSLLICNCVCKKWNSIISNPEFASLHLKKSPFSN
DQSLLINTKTGFLSFDLENFGVKVIIETTTDDHHHLNVSVVASCNGLVCLDDEATNSLYI
WNPITSKKIRIPYPQPLVTTQVVWGLGYVSSTEDYKLMRIYNENFDQKVQIFSFHNNTWK
NLDIEYEMCSFEELPPINGSGVSVNGMIYWATYYTEYDVGFYDHCFNILGFDVMKEKFMP
LTPVPEWSDRGFEQNSVLFLSNGCLCACWRTDEGDIDIGMLREEEAGKQSWVKHFHFDHG
SLLYDRKISFQKIQGVTKAGKYAVHVDGEHIILLDSNQDSSKEVQLKIPRTRNVIGYVKS
LLSPSNMVSYKN
>Sgl74587 E3_adaptor/Cullin_RING/SCF/F-box 11.9 0.0
MAETSSSSSSLSLASANVFDLLSEEIVFIILDYLHDNNPQDRKAFSLVCKSFYSIESKHR
RTVKPLRAEHLPAVLNRYPQISTLDLTLCPRITDFSLSIIASNCAKTLRSIDLSRCKFFT
GSGLEILVASCRNLVALDLTNATELRDSAAAAIGEAKNLEKLWLGRCKLITDIGIGCIAV
GCPKLKLIGLKWCLGIGDLGVELVAVKCKDLLSLDLSYLPGLMTFVAYAFCGITSKCLPA
ILKLQYLEELILEGCFGIDDDSLTLLKQGSKSLKTLDMSSCQNVSDTGLSLLTSGTGCLR
QLTLAYGSPVTLDLARSLQRLSKLQSIKLDGCLVTCSGLQAIGNYCASLRELSLSKCSGV
TDDGLSSLVKKQKDLRKLDITCCRKLTCVSIAHIAYSCTSLTSLRMESCTLVPREAFVLI
GRKCHQLEELDLTDNEIDDEGLKYISKCSRLSILKLGICLNITDVGLSHIGNRCSKLVEL
DLYRSMEITDSGITAIARGCPGLEMLNISYCNSITDASLISSSKCARLNTLECRGCPLIT
SLGIAAIAVGCKHLTMLDIKKCYNINDFGVLPLAHFSQNLKEINMSCTSITDVGLLSLAS
ISCLQSMIILHLKGLTPRGLAAALLACGGLTKVKLHSSFKTLLPRPLFEHLEARGCVFQW
REKMFQDELEDSKSWKMQVAELNNDS
>Sgl74598 E3_adaptor/Cullin_RING/SCF/F-box 13.7 0.0
MQRVRISSKHSPVFKLGDSQLSLSPKFRVAAIKSHLDDPSSDLELAIKGQPLIPGLPDDV
ALNCLLRLPVQSHGACRAVCKRWHLLLGSKERFFTRRKELGLYDPWLFVLTFHKCTGKMQ
WLVLDLTHFTWHTIPEMPCRDKVCPHGFRCVSVPNEGTLFVCGGMVSDVDCSLDVVLKYE
IHKNRWTVMNQMITARSFFASGVIDGMVYVAGGNSADLYELDAAEVLEPSKGCWRPIASM
GTNMASYDAAVLDGKLLVTEGWLWPFFVSPRGQIYDPRTNHWENMAVGLREGWTGSSVVV
FDCLFIVSEHERMKLKVYDLNSDSWEAVEGQPLPEQICKPFSVNSWDSSIYVIGRDLYVA
VGQISKVILEGHSEKKLRFSVRWHVEDAPMAFSDLTPSSSQVLFA
>Sgl74616 E3_adaptor/Cullin_RING/DCX/DWD 52 0.0
MALGDLMATRFAHSTVVVSNHLDEYISRDDAELYRDGDRDLPETASTSGGGNGYENAIIV
SSAAAAGGNTSTTTTTAISMMYFPQTIVFCELRHEAFEDSVPTGPAESGLVSKWRPRDRM
KTGMVALVLCLNISCDPPDVIKISPCARRECWIDPLSMPPQKALEAIGKALSLQYERWQP
KARYKCQLDPTVEEVKRLCNTCRRFAKAERVLYHYNGHGVPKPTTNGEIWLFNRSYTQYI
PLPITELDSWLKSPSIYVFDCSAAGNIVNAFIELIDASAASGATKDCILLAACEAHETLP
QSAEFPADVFTSCLTTPIQMALRWFCKRSLLRESLNHSLIDKIPGRPNDRKTLLGELNWI
FTAVTDTIAWNVLPHDLFQRLFRQDLLVASLFRNFLLAERIMRSANCSPISYPMLPPTHQ
HHMWDAWDMAAEICLSQLPSLIDDPTAEFQPSPFFTEQLTAFEVWLDHGSEQKKPPEQLP
IVLQVLLSQCHRFRALVLLGRFLDMGPWAVDLALSVGIFPYVLKLLQTMTPELRQILVFI
WTKILALDKSCQVDLVKDEGHTYFIRFLDSSEAYPEQRAMAAFVLAVIVDGHKRGQEACI
EAGLLDVCLKHLQASTPNDSQSEPLFLQWLCLCLGKMWEDFPDAQIVGLQAGAAVISASL
LSEPQPEVRASAVFALGTLLGVGFDSSGDAGEEESDDYEISILKSLLNVVSDGSPLVRAE
VAVALARFAFGHNRHLKSVAATYWRSQPNSGFSALHVNSTGSGYNTPNNYMSPGSIVTSQ
MGLLRVGGDNTPIVRDGRVSTSSPLATTGIMHGSPLSDDSSQHSDSGASNDAVGNGIMNH
ARPRPLDNSLYLDCVFSMCALAKDPSPRIARLGRRVLSIIGIEQVVARPIRPSTSSTRPG
EPSTSAGVRLAGLARSSSWFDMSSGHIPLTFRTPPVSPPRASYLTGIRRVSSLEFRPHVL
SSPDSGLADPLLGYGGSSGQNERSLLPRSTIYNWSCGHFSKPLLTASDDSDELIVKREAK
ERSARDLITKCQHYSVTKLNNQIASWDTRFETGTKTTLLQPFSPVVVAADEKERIRVWNY
EEPTLLNSFDNHEFPDKGISKLCLLNELDDSLLLVASGDGNIRIWKDYMQKGKQKLVTAF
SSLPGHGPNARNVNAVVDWQQQSGYLFVSGEVRSIKVWDLDKEQLVHDVPSSPDSNISAL
AASQVHGGQFAAGFADGSVRLFDIRTPEMLVCATRPHIQRIERVVGIGFQPGLDAPKIVS
ASQAGDIQFLDIRNHRDAYLTIDAHRGSLTALAVHRHAPIIASGSAKQLIKVFNLDGEQL
GTIRYHPTFMAQKIGPVSCLAFHPYQVLVAAGAADPFVTLYADDNNPAR
>Sgl74641 E3_activity/RING/U-box 106.8 0.1
MVSSPTIFPQRRRRPPPTSFLPPQLSTVDLLSSLYCLSSEISSLHPPQHLFKRNSSSIIR
KCRILSVIFEEIYRHKSSINPSNPSSLLCFEEMFIVLQRIRALIEDCFNGGSKLLLLMQI
EPISSTFHELTLDLWTLLEILPKKELNLTEDVDELRNLVIKQCCNDKSFVDPSDNRLRIE
VLKLLDSIKKEIVPNQSKLSEILSKLGITDSASCREEIEWLEDEIQCQNDEKSKSEVISL
IGLVKYAKCVLFGASSSSGSSNNFSDESFRRNSLSEMNIPTDFRCPITLDLMIDPVVVAT
GQTYDRGSIVLWMESGHNTCPKTGQTLAHTSLVPNKALKSLIAMWCRQHRIPYAAAEGSE
GRNRGVALNKAALEATKMTVSFLLGKLGGSPQPVEMVNRVIYELRVFAKTDSDSRACIGE
AGAIPLLVRYLGPEHPKLQVNAVTTLLNLSILESNKVKIMETDGALNGVIEVLRSGVTWE
AKANAAATMFSLCGVSAYRRRLGKKTRVIKGLLELAREGPTSSKKDALVAILTLAGDRET
AGRLVEGGVIDMVKEVMEELPEEAMTILETVVKKGGFIAIAGVSHMLGRLVAMLRTGTDR
AKESVIATLVLICRKGGAELVSELARITTIEVVIWELMGTGTARAKRKAASLMRILRRWA
AGLDGRLVEAFSVTMALE
>Sgl74664 E3_activity/RING/RING 35.5 6.5
MNMQRKLLYTAVAAPATASDNNNNRTSSMDSQLTQANFDTNMVIILAALLCALICALGLN
SMVRCFLRCGQRFGMESADHAAARMSSTGLKKSALRKIPVAVYTAEDSKTGGKSDTSTDP
SEDVECPICLGEFIDGEKVRVLPKCNHRFHVSCIDTWLGSHSSCPNCRLSLLEVCTSSTT
KAADGEVGASEEPPWGGERQDHVVVEVSGGS
>Sgl74735 E3_adaptor/Cullin_RING/DCX/DWD 108.6 22.5
MAKLETCSAGELGSGISNHDEEEKDVFLDDSDIIEEFLLDDEDLPDADADADADADADDN
ESDNEAVSEGMSETDDAIDIFAHGTDPMYAVACNPKDATLVASGGGASLAWFWRIGCEDS
VNELEGHTDTISCLSFSEDGQLLASGGVDACVKIWDLSGNLKSMFEGSAKQYEFEWVRWH
PSAHLVLAGCTDKTVWLWNADKGACINVFCGHGDHVTCGGFTPNGKSICTGSLDATLRIW
NPRSGQGNIVQGYREASALTCLSYTFDSTLALTGSENGFLSVVNIARGKVISSFSSHSGA
IECIGVSKSMPWVATGGVDQKLVIFDLQHSASRSIFEYQDGVTCLEWLGGESTYVASACG
DGQIIISDARSEENVRSFKGHSERIQQLAVSADNNYLVSASEDGTCRVFDISEFK
>Sgl74737 E3_activity/RING/RING 36.8 10.4
MESAGGSSDGHRDRERERGNSANSGLRRYRLPLQLSAANLIRSPVSTLLEYSGLLRPRSE
SEPLIGGNGTTSASHTHHDSSSNGGEVSIRIIGASEQDHDRIDQATATTTGGQLQPCPAD
VSAQSLPMAVSSSGTDGQEDLRSDRAANGDAHSGVSQFSSSSTDAEAADGGGANNRDANY
QRYDIQQAARWIEQVLPFSVLLIIVFIRQHLQGFFVTIWIAVFMFKSNDILRKQTALKGE
RKISVLVGICILFTLHVAGVYWWFRHDDLLYPLIMLPPKEIPPFWHAIFIIMVNDTLVRQ
AAMVAKCTLLMYYKNSRGRNYRRQGQMLTLVEYLLLLYRALLPTPVWYRFFLNKEYGSLF
SSLMTGLYLTFKLTSVVEKVQSFFAAVKALSRKEIHYGAYATSEQVTAAGDMCAICQEKM
HAPILLRCKHIFCEDCVSEWFERERTCPLCRALVKPADLKSFGDGSTSLFFQLF
>Sgl74740 E3_activity/RING/RING 25.8 7.1
MELNMQTTSQELSHLNFLDRIESGVANDQLHMSVTCGFCGRTLSLEDEVTSRLQRASVCN
DCKFLLLEDFGTPVHNSSRRRLPGSSVINGSPESVENFSQQFSQIINLARHVEHEHEDAR
GDTNLNTLGLQSASSRTTPNGSNRWWRILSDTESDGFNTDLFYGESESNFSGGAYRIYHG
DSDVISFSTYDGDSIASVDGPTNFDTDMYGQSLERSDIDSDTDIDPMHAGVVDWNSDEYQ
VEDSDWGEVDVRLQETGTIIDSSAGSDYFVERGSMDSFQFEEMISQRLGEIRYLQNARVL
TSMEDFGEAPHDGNSEDYLDTRRYEDFLERILETNNSRRGAPPASVSFIDNLPLVVVSDE
HHKHDGLPCAICKDLLVIGSKVTQLPCFHLYHPACILPWLRARNSCPLCRYELPTDDRDC
DWSKRNNSHGMIVSEIQHQQDRDDSSSVATDSSEIDETQNFAARMEDVGTAAELSHTNGM
RGGWLLRAAAPIVGLAGIVIVLWLGNPLAGRRGSTVQSNLHGWPAQPIHTSDLCPRNQQE
KRWWWWF
>Sgl74768 E3_activity/RING/RING 30 5.6
MASRNSLSQSLHPAPTHTRGVRSSYSHRSTPNSRASMGNLRMSHVAPPDDSLQMVGENHS
TRHPRPFGPVGWRNGDRSGRSRLSCERYRLISDDAGVHERLTPEGLMIVDRASLYASRNN
LDQHREMRLDVDNMSYEELLALGERIGSVNTGLRDDQVPRCMTETVYCSSDQVQEEGRCV
ICLEEYNHLDDVGTLKTCGHDYHVSCIKKWLSMKNACPICKGPALPDTTKEKEISKMHGC
FIYYPFFVGLKRIDAAVDALTPMGFPPNLIRRKVKSLLKAYGEDGWVFIEEAAYKMLIEF
ILEEQEQCEQGEPSSRDSQIDEVRDQGGGEAEQTPLIEGSRDQGGIEAEQLEATPLIGGS
ESTWPNLDVATPMTVRDAPMDNPSLERRPCLGWMDPDDDDQSFILLEPAPVLGWGNSKEA
REAEI
>Sgl74770 E3_activity/RING/RING 30.1 5.6
MAHRHIYNASQIFEAEPDQHWNLVHGEDPYLHFARSSSAENAPIFHPVENGPVDQAHYVS
PWNAATRLSGYSSPSPMVNPPPYQPDTPDPSRDLMHPSAAGNVFMLPENHVHHASSSNYG
VDSNFFDLSMGNGRGPYKRKCPAITDRGSTSRYYCPGSSSDVSSSSDLRQEKSAVDVQHG
HWDSVTVPASYRTNQLSIGGEPSIRNVRSRSTLDLEPDAFRTHLPANYPHHPSSSRHPID
HSSAVDPIQNSNVTLPEWNPIHVSGAPHGRTIVPSNLNHESNHFFAGSSIANSSGEMAGY
HHEHMASRNSLSQSLHPAPTHTRGVRSSYSHRSTPNSRASMGNLRMSHVAPPDDSLQMVG
ENHSTRHPRPFGPVGWRNGDRSGRSRLSCERYRLISDDAGVHERLTPEGLMIVDRASLYA
SRNNLDQHREMRLDVDNMSYEELLALGERIGSVNTGLRDDQVPRCMTETVYCSSDQVQEE
GRCVICLEEYNHLDDVGTLKTCGHDYHVSCIKKWLSMKNACPICKGPALPDTTKEK
>Sgl74776 E3_adaptor/Cullin_RING/DCX/DWD 60.2 12.7
MMNSANGMMNPSSSTSTATTTSNIQSATCLKNYFKTPEGRYKLQYEKSYPSGLLHYTHGK
TVSQVTLAHLKDKPTQSTQATTSGAGVASGVRSAAARILGGGNGRALSFVGGNGGSRYAS
STSRNGSFGASSLSNSNNLNFDGKGTYLIFNVGDAIFISDLNSQDKDPIKSIHFNNSSPT
CHAFDPDAKDGHDLLIGLNSGDIYSVSLRQQLQDMGKKLVGTHHYNKDGTINNSRCTSIA
WVPKGDGAFVAAHSDGNMYVYEKSKDGNGETLFPAIKDQAQFSVAHSRTSKSNPTARWHI
CQGSINSVVFSSDGIYMATVGRDGYLRVFDYLKEQLICGGKSYYGALLCCAWSGDGKYIL
TGGEDDLVQVWSMEDRKVVAWGEGHNSWVSGVAFDSFWSPPTSDDSGENSVYRFGSVGQD
TQLLLWDLEMSEIVVPLRRAPGGSPRIGSPTYSTASQSPRWDSACPAGSLQPSPSMRDVP
KLSPVVIHRAHTEPLSGVIFAQDSVVSACREGHIKVWMRPVCTDNQSGNSESVLNVGLRE
KPVLVAKSGTSGFKP
>Sgl74784 E3_activity/RING/RING 22.9 13.1
MGNTGSSATSNGANRRRQNSRRHHPQPPPPPPQPQQQPPPSEVTPNRYVFAAASPYPSAG
YYQYHPPAPGYYPPPPPPPHHNGSIPMSMPLPAPYDHHHQGQGQHHPNWAAAGRFHYGPM
VPPSHPVPHPPAVATPYVEHQKAVTIRNDVNLKKDSLRVEPDDQNPGKFLVAFTFDATVA
GSITVIFFAKEGEDCKLTPMKESVLPPVIVHFEQGLGQKFRQPSGTGIDFSMFEEAELLR
EGDIEVYPLAIKADACPPTETGTDGEPVPGSINSQITQVVFEKDKGEYKVKVLKQILWVN
GMRYELQEIYGIGNSVESDFDGNDPGKECVICLSEPRDTTVLPCRHMCMCSECAKVLRFQ
TNRCPICRQPVERLLEIKVNNGNEEERSE
>Sgl74830 E3_adaptor/Cullin_RING/SCF/SKP1 100.3 0.3
MASNTKIILKSSDGVTYEVEETAALKSQTIKHMIEDDCADNVIPLPNVKSKILSKVIEYC
KKHVKSSASTPSTTSSSDHQHGQVVDDELKKWDADFVKGLDQDTLFSLILAANYLDIKSL
LDLTCQTVADMIKGMTPEQIRTVFNIENDFTPEEEAAVRAENPWAFQ
>Sgl74838 E3_activity/RING/RING 19.9 13.2
MTIRKRSSFTNDETEYKDEEIRKKSKQHEAGLNNKQQQQQLYKGMNNYTDYRACFRRAKA
AVVGPQRCSPHIRATTTYDYQPYVCKDYKETGYCGYGDSCKFLHDRADYKSGYQIDKEHE
LEESNRARKIVSGFDKLDDDDDDYHDNSVGSALACQICKRTFVNPVVTKCKHRFCERCAL
KHHSKTKRCFVCNQPTQGIFNVARDILKNSR
>Sgl74849 E3_activity/RING/RING 24.8 9.0
MPRRFRRSVDEFLGDHFIAVDEDYEEQEEDDEEEEEEEEEDEEEEEEVAEEQEEADYADD
SEVEEVFVHNPRNSAVMAPRVSEIEVRGKDDAVMVDSVPSSSGRDDDGEGEGCLNREEFE
GLICSICLEPWTSSGEHQPSCLSCGHLFGMSCIKKWLGQRRNSGKCPQCNKKCTLKDVRR
IYGSRVVVVDEESQKRIRFLEAKCDSLAKKDEEWRKKEVEWHMKVLVLQKKDEESCQKLQ
QANERVNYLERSIAEMENKSQISAATDGFHQSAGGPKSGLLYLPVSYHTFDLQQELVVDG
ARHFDVDDTGQMLIMARKLTRGGECHVLTKMSLVSPHEQDNVLLPSAVRDLHLSSFARLA
LLVSTGRKLSVFSMESNNCVVDYDLPAAAWSCSWDSNSSHYIYAGLQNGKLLVFDLRNTG
GPVESRNGLTCNPIHTIYSLLEDSPAHTGVKKLLTASQVGVCEWSIGGENEEPSLLADTA
NQGICVSLAHCPSSDNIVATFRPKVKAQDEPDDPRITQVSQVCPSFSLGNPVQGSQVFMQ
RVNSRYQKFASIPASVPSIRLPKSAIFGMGDGAHVFACVRYFNKAQSTMLLESGEIAVVH
SKIFVRETFSWSLGEFFGDLEDYKLSTVYDA
>Sgl74873 E3_adaptor/Cullin_RING/DCX/DWD 63.2 2.3
MSLIAGSYEKFIWGYKLKNPKTLKTLTLIPKFSYAAHLSPIKSVAISGIVAASSAGDDTI
KLYDLSTSSELGSILLESSITSLTFFAPQSLSSFPRNLFGGAEDGSLSIFDVDPFVNLKT
ISVHKRAINDIAVHCSGKLGLSVGRDLGLCMVDLVRGKKSFGCKLGNEATIVEYFCEGEK
FFMGFDDKVCVHDAEDAKLVGEFQVSKRVLCAAPGENGIIFTGGEDRAVTAWDTTSGKLA
YSIDDAHKSRVKGIVVLSRDNNSGATENPYLLSSASSDGVIRVWDVRVTNKEKSKPLSEV
DTKSRLTCLAGSSFKSTTKPETKDPTENNAEEMED
>Sgl74891 E3_adaptor/Cullin_RING/DCX/DWD 145.2 35.7
MVKSYLRYEAAATFGVIASLESNISYDKTGKFLLSPALEKVGVWKVRQGVCSKTLSPSLS
SPGPSLAVTSILSSPSSSSSLVAVGYADGSIRIWDLVKGTCETTLNGHKGAVTVLRFNKI
GSILASGSKDNDIILWDVVGETGLYRFRGHRDQVTDLLFLDSGKKLVSSSKDKFIRVWDI
DTQHCRQIISGHHSEIWSIDSDPEERYVVTGSADLELRFYSVINPDLEVGETLGSSGHKK
SVDDVPSSANNKWEVLKYFGEIQRQTKDRVANLRFNKAGNLLACQVAGKTVEIFRMLDEA
ESKRKAKRRVHRKKEKKEKKEKKEKEISKSVTEVTENGDQKNASVDEEGNPAIVVSDVFK
LLHILRSGKKICSASFSPINTKNSLATLALSLNNNSVEIYSVESDSSIQSLAIELHGHRS
DVRSLSLSQDNSLLLSTSHNAVKIWNPSTCSCLRTIDSTYGLCSMFVPGDASNKYALVGT
KGGKIEIIDVASATCVEVVDAHGGSIHSIAGLPDKSGFVTGSADHEVKFWKYERLQKSGE
DLERLTVSHERTMKMNDDVLKIVLSPDAKYIAIALLDCTVKVYYVDSLKFFLTLYGHKLP
VMCMDISADGDLIVTGSADKNIKIWGLDFGDCHKSIFAHADSVMDVKFVANTHYVFSVGK
DRLLKYWDADKFELLLTIEGHHAAIWCLALSSRGDFIVTGSHDRSIRRWDRTDEPFFIEE
EKEKRLEEMFEGDLDGAHENRYAPKDELPEEGAVASAGKKTQETLSATDLIIEALDMAEV
EIKRIAEYEEEKRRGTSTKFQPNLLMLGLSPSDYVLRSISKVQPNDLEQTLLALPFSDAL
KLLSYLKNWTSNSEKVELICRVAIVLLQTHYHQLISTPSARPVLSELKDILHARVKDCKD
TLGFNLAAMDHLKQLMTMKSDAPFREAKTKLLEIRSQLAKRNAGTTDTREERKRKKKQKK
GSDGHAWTVVR
>Sgl74911 E3_activity/RING/PHD 37.5 23.9
MKRELAALETKSPIKSPMVDSIGRKTRASTRSSGAPLSGSLVYKRVKRSHVKKAELLSNG
DNGVSDDVSKENGGVGKQNGVHDEGDEVEKGLVVLEESGNGVAAGVCSEVVKEVCDEGVK
KSEDSMAAEEGVKESEDSMVVEEDGVKDVLPISVIVMGVTAVDGVMSNVKSNDVEVNNGL
VEEEEGSKKGGNAELGDDLHGNGGSIEVYKEKVVKGKKSALKGVNGNAKSNSVEYPRRFT
RSALKSKVDTVAVGSEIVENGENTKVVGEESNGEVRSELAIVVYQTPESKEEVKVSPAPK
FTRRLTRSASKSKVEGSTVCPAETVTLDSEKGALVVRNDNAECDMDKLDEEELSSATPRR
KLEMKMSKQISPTKTPTTVLELFGTGMLEGCPVYYDGGKGRELHGRIRGIGILCSCGTCK
GMKVIPPSMFEIHACNTYKRAVQYIYLENGRSLIQILKACKNNRFNSLAATVQNAIGPLP
DKKVIVCQNCKESFSTMDAESSEPVCSTCVMSNLSPIGPVYSSRKRSRSSNVFLPCQAAS
ACDVVQDGSEQKGVQKSPKASRTPKLKTSQVDLPSDMLQSRRRPKSVKKSADGFVTPTLR
RSSRVEKNSETKTSAETVKRSEEASMVPNTSSSPVLGSSEAKHRNKLKKRSFKSALSPKP
SKSTRMEKCSPRNDGAKSTERLKKRKKESLTPKPSRTPALRSSEKKSNGKITRKDLRLHK
LVFEDDVLPEGTELGYYARGQKLLDGYKEGSGIHCNCCDTVVSASQFEAHAGCASRRKPY
CYIYTSNGVSLHELSVTLIKDRRHSAKYNDDLCSICADGGSLLLCDGCPRAFHKECASLP
SIPVGKWYCKYCENMFEREKFVAHNANAVAAGRVSGVDSIEQITKRSIRIVNNLASEVSA
CILCRGHDFSKSGFGPRTIILCDQCEKEYHVGCLKDHNMADLTELPEGKWFCSVDCGKIE
SSLQNLLVRGVEKLPEYFLDIIRKKSMRSDSRTKMNVSWRLLTGKIATPETRTLLSQAVA
IFHESFAPIIDVVSGHDLIPAMVYGRNVGGQEYGGMYCAVLTVNSVVVSAGIFRIFGPEV
AELPLVATSSGNHGKGYFQILFACIEKLLAFLKVKTIVLPAAEEAGSIWTDRFGFTKMTS
DQICELKRNFWSMVRFQGTSMLHKLVPESPVTES
>Sgl74920 E3_activity/RING/RING 27.8 13.4
MEEITSSIHKKSSKNNYLPILVISVGAIITTSVALSLLHIMFIKYCKRRHDRSSQTLNIE
QSSVSIGLDKRVLNTIPILFYSSKTRDLYRVNQGDECVICLQQLNKGDLIRCLPSCGHVF
HVPCIDHWFHAHITCPICRARVRAPRSRTRALPRTRSGGVLRHSTKLVLPIQGLGPRDLV
NVGLKRSLSMDECCVVIDTNEEQTSSSSSSSSSSSSSSTLGSSMINTNINPCTNPPLSKI
EFLISRLYHANSYRRFNYVPRSLHGLREGRGGTSRNNGILPY
>Sgl74938 E3_activity/HECT 339.3 0.0
MDDSKKNLVSLRGASAREITRDALLERVSHEREQRNFARRANSAALFIQRVWRRYNVTMK
VALKLQEDWKVSVQDASGKMKKSWISGFLLRPFLFFITPLSLRQGTIQSQAVNSMRSCFV
ILLENLNSTDPEINFCSLAMGTIEEQRIWSYQVKKLVSLCSFILLDYDSYSVRNSDVAAV
TALLMRLVITLTDSRAWKCIPDEKREDANRAVKDLIRYIGCDKSGLFRSIGRYMTKLNAS
LTSQSVVQKDDKFLITASAITLVLRPFLAFNSDGNDPLPLDVRFAAEQYCLFILTVPWLV
QRIPAAIVRALKHKSILMPCIETLLILNEKILMEYSRMDLSGVSTNNDMPCVGWVISNII
SLVTESENGSIQSSSFTDGINIVGYVHVLNILANRLLTEIENNQFKKKGRLEVEDGTATG
TLVDKTFGSLNYMDLLRPVCQQWHLSKLMATAKSKISTAVTDSSMSISGFKRIKVLELVD
IAHCYSFIIRIYSALNLMLGPLPVLNMLSFTPGFLSSIWGALEHAVFPEAALVFEKDMYN
ASEMHENRSAGTSKRKQKQPIKDGAAKWVNVLHKISGKSQTDADNGSDANYSQAGVSQGK
TDLDDIWDVESLRCGLESISKEKSCLIHLFCATYAHLLLVLDDIEFYEKQVPFTLEQQRR
IASMLNTLVYNGLLHNTGRQNKQILDAASRCLQMLYERDCRHRFCPPALWLSPARKNRPP
IAMAARTHEVQSDVRSDDNLTFQSMGSFITVTPHVYPFEERVQMFREFIKMDKTSRRMAG
ELNAPGERSVAIVVRRGHLIEDGFQQLNSLGTKLKSSIHVSFVSECGLAEAGLDYGGLSK
EFLTDISKGAFDPQYGLFCQTSTSERLLIPNTAARFQENGIQMIEFVGRIVGKALYEEIL
LDYSFSHVFVQKLLGRYCFLDELSTLDPELYRNLMYVKNYEGDVKDLSLDFTVTEESFGK
MHIIELRPGGKDTSVTNENKLQYIHAMADYKLNRQMLPLSNAFYRGLTDLISPSWLKLFN
ASEFNQLLSGGKHDIDVDDLRKNTRYTGGYSEGSRAVKLFWEVMTDFEPKERCMLLKFVT
SCSRAPLLGFKHLQPTFTIHKVVCDVPLWAAFGGQDVERLPSASTCYNTLKLPTYKRAST
LKAKLLYAINSNAGFELS
>Sgl75029 E3_adaptor/Cullin_RING/BCR/BTB 21.2 0.1
MAATTLEEEDDWLVIECTDPNTIQRSSDIVTPAEILISTADISSWDLPFILTHRIVRVNV
NRSRLIEQSSYFQSLLSGNFSESSMCCVSVEWSLETFLLILRFIHGCHIEVTNCNFLPLC
HASLYFGLDRLVLECRNWFSNIVTTVDNLKLDELIHFWEFGFDQAIDWISAVCISHVAKN
FMWALSCETFVALPFEFLVSCVKHPHLTVDSERHLCEALLAWVRADMEPLEYTCSLNYDS
GEKSKQITHDCTRILDEVRVNLLPLWFIMGSSKYWYFSIIAKQGVSAIVNRLNRFFKDPK
YIVDARDQSYMRIRLTDYSKKLDLSGCPQISSSDILFSMLQQTTSVGLLLEGIGQKSVDL
ECPKWLSSLTTVSCEEMMEVDISKCSLLNLGAALECFRKSFPFLRTIRMAYFLDFETKRL
RQLLESNHSICEVDLTVDVSPLISSNISVLHSEPVSRSSLKRYFDMSSCRGKETKSNITK
LTLEGRSDFSDRELLHIADVCISLCYLNIRGCSAVTDVGIANLILKCRKLHSIIATDTSF
GENSASALCSRFQDDGCSQMEINKHHIELSDIYLEVLHIGGCKGVSETSIGDILSRGRMI
KNLCLSDTLLVDQVLYRFPGSSLEILDLSNTMISRDALSYMLNKNLGLKYLNAKGCNKLC
ADQFKLKEDLFSSDPCDQWFKLLGQECKLEELIIGWGFSFFSLNSLGPALKSLKTINVGL
GGSLGPEGLIKLCTLSPLLESVTIVFQVICDTLIMNLLGTLRNLQALSLCYCIGDISPLS
LKHSVPSLRILKLERVTPWLTNDDLALLTQNFANLNELSLVGCTHLGEDSQRIISSGWPG
LISLHLEDCGDVTAKGTGFLFNCMALEELLLRHNGPGIQKDFVLDAASGLPMLRSISLDL
CDAIEGEFDLPKATFIDSDMLRYNEMGKTTTGSSWCGLIKPGKSSLLKLKGDQWLQLKLE
RPVLWEFGMLLSQLQTSVAAHESSLGCLSSFGKPKHAAYTRLYFPSSCDINELSILASKE
V
>Sgl75049 E3_adaptor/Cullin_RING/DCX/DWD 34.7 9.7
MEVQNIHRKPMEEVENNKRMKTGNRKIREVAESQGSEAAAAAAAAAATVPLIESTPTETS
KATSSHDNSEIRVSMFDHCVENHFKEMDMIFKLCGEEETGGLVDEEIERIASSITFLREW
RYFNYRPRTIRFASETGCPGGIKAHNEITLSQFSAAVVPDCDAEAKNGPGGVVSSNDSRK
DFALYVGGLVWSLDWCPRIDQETISGSKCEPFVCYSIPEFIAVAAHPPDSAYHKQGAPLS
GRGMVQIWCLYSHMTQEDMKAPVGKIKKKYKMEKVANKEENKPVRPRGRPRKNPVVKDPA
KDPEGPFTQAIVVHLPEKSSVVPPADETMQSIYNDITPVSEKDKDQINAENEILTNNANE
EKLQEEEKNPKKPRGRPRKNDKTSIEDPEGQIIPALAVCLPEDPLSGPPMDKNMPSDSAP
KKGKERKRKAVNDGTIPKENTSGIPSSEGPSVQEVPECIKNISPAENCLLYTNGVHENMG
KKRMRKGVLVTDLECTLAVLRRKSRNKPKVCNSLDTENTVLSIHNEGEEPSLASLEENYL
RKDNRITEGNDLGNNLSDLACVGCHIQEKDVLPRVVLCVGHDGKVAWDVKWRPLNGDVAA
NKHRMGYLAVVLGNGSVEVWEVPSVKVINRIYASRLAKGTDPRFAKLKPVFRSSILKYGG
KNSMPLMVEWSTSPPHNLLLAGCHDGVVALWKFSVDIPSEDARPLLCFRAETGPIRSLSW
APYEGDPESSNIFVTAGHGGLKFWDLRDPFRPLWDANPSQRFLYGLDWVPDPRCVLVSYD
DGTLRMLSLSRAAYDVPVTGQPYSGTLQQGLNSYSCSSFAVWSIHVSRRTGMVAYCCADG
TVLYFQLTHKAVDKDPLRNRAPHFLCGSLVSEESTVTMNTQLPDSPHQMKKSATEWSNTP
RPSRTVASRKVQAKRTRKGTEKSQNLDDQVLALDYGDDTESRVTNETQMSTKDGKGKTSS
SKAKDDQAFMSSVDDGENTNGKPEVKEEANKAFEAFPPKEVSMYRVRWNLNKGSERWLCY
GGAAGIVRCQEIVAPVFDKKSLRWSKP
>Sgl75065 ULD/UDP/UBQ/UBQ_PIM 97 1.4
MQIFVKTLTGKTITLEVESSDTIDNVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLADYN
IQKESTLHLVLRLRGGAKKRKKKTYTKPKKIKHKKKKVKLAVLQFYKVNDSSKLQRLRKE
CPNAECGAGTFMANHVDRHYCGKCGLTYVYQKAGGD
>Sgl75070 E3_adaptor/Cullin_RING/SCF/F-box 20.1 0.1
MYSLCYVYLPENIIFEILLRLPPKTLIQCKTVCKQWKSIITTPFFARSQLRFLKQQFNLP
PYYLLCSYDWSFALHLNRSYYRQNISPKELDDQVLPLSSKSFKLTSSEDVLLSTCNGIMC
FYLKKKNSLCLWNPTIDETRFVALPYESYWIRKFYFAGFGYASSIDDYKIVLAAKYACHT
IITSTDRSSLSVYSLRRNEWRELDFDYYKSIAPEIYSGLGWRSGRQESNGIRMESIVVND
ALHWLMDSCIYNTYMKLFLYKFDLVNERFEKVVDLNKISNIVDDENRLAPRQTEIGVTEN
NTLIIYRLYSEFCHSNPSNELQVKRDVVKAWEMADQYDYNSWKTKLRYVGDWDDIRDNHD
LLQITSNGNVLIIGGIFAEYKSRLWFGQYSHKQRAQDVAFYAKYYVPSLISPNNF
>Sgl75128 E3_activity/HECT 324.7 0.0
MEDSLTESRGQKRSDMTEELPADKRACSSLEFRPSSSTVTPETLVSSSSTAVEAHGGDME
TSSSSASASGHSEGDGDRDSPYGSCDSDDMDDDDDHRYSSLRALQRSRSYNDSSKFDRIL
SSLSSDAEPSGQLAALTELCELLSFCTDDSISSLVADQLTSALVKLAKHEDNPDIMLLAI
RALTYSCDAFSRSSGLLVRHDAVPALCQKLLVIEYLDVAEQCLQALEKVSRDHPITCLQS
GAIIAVLGYIDFFSTSVQRTALRTVVNICKELPSEYSSTVMDEVPKLCELLQYEDQQLVE
LVATCLIKVTNCVKDSPEKLRQLYDRGLINQVTHLLELNSRITLSHTTYTGLIELLATIA
SGSPDAVKTLFELNIGSVLKDGLSKTDLSHGTPSPRSVDNNCTQVLEILKLLHELLPDVA
KDEKELLSFTERILLDHPDNLQTFGVEILSTLLQVVSSGANLYVCYGCLSVINRLVYLSK
PETLLKLFEGINIASFLAGVFTRKDYHVLLIALQISDTVLEKLSSILVPAFVKEGVLFAI
DNLLMPDSCSQQSFPKISSSQSVKKIAGKGAMRCFCFAYHNRQLKSTPDSETCKADKDSV
HSLAEHVKSKHFIAELLGPQSMVTDLLQDLRNASLEMNDILTVSPAKESDSHTDDRLCRN
LEKIILQLGGNAPVSTFELIESGIMKALLNYLSYGHFLSNALKPNDLTHAYGVQKRFEAF
ARISLSSPDPASTGLPLSFLVRKLHSALSNVENFPVVAGFGTKQRGSYATVPSGRSIMHP
CLKVRFLREEEELCLHDYIKDVVTVDPFCLVAEIEKCLRSKVIQRKKGSSESQLQSSESK
PKAEEVLHDISSLPGKSVELQGSGSMCTVSPDMQEDGDGKSLCSAMETSNLGQTTVVEAR
VTSEVQSKTQEDKDHSSDGADNMTEISSTCLNADVGNSKDQSQVCSNNEDTPKLALYLDG
EQLDYSSTLYQEILQRQIKSHHELHNSSKLWSSTYTVTYRRVEENESVSKKGREMHDNGS
IDEVLLCQQLMPLFSSIFVDKLGSELDLSSSSSDILLLLKSLEMMNRFAYHLVSYERMRK
FAEGQLHSLDDLKGSLPMLSQYEFVNSRLTEKLEQQMRDSSAVHVGALPLWWCQLIARFP
FLFGFEARCKFFQLAAFGRVHALPYTSSLTDSSMSRDRRTSTGSPPRKKFRVHRESILES
AAQMMDLYATKKVAIEVEYSEEVGTGLGPTLEFYTLVSHEFQKAGLGMWRGDYMSLTNSC
NQQGSNSGYVVSTSGLFPRPWSSTSSSINGIEFTDVIKKFILLGQFVGKALQDGRVLDIP
FSIAFYKLVLGKELSICDIQSFDPQLGRTLLEFKALASRQKVLSPACSENIVLGDSKMFR
STNVEDLCLDFTLPGYPDYALSSGMDDEMVSDNNLEEYISLVLDATLQTGVSKQVEAFKT
GLNQVVSDKHLQIFTEEELERLLCGERDSGLSVDLFDHIKLDHGYTAGSPPVINLMEVIS
EFTYDQRRSFLQFVTGAPRLPPGGLAALNPKLTIVRKHSSNCPDADLPSVMTCANYLKLP
PFSSKEILKEKLLYAITEGQGSFHLS
>Sgl75289 E3_adaptor/Cullin_RING/DCX/DWD 146.3 27.3
MNSQSNEGEIEEHGDVFLDESDIIQEIPFDDEELPEADEELGSDEEHVETADDSMHTFTG
HSGELYTVACSPTDPTLVATGGGDDKGFMWRIGRGDWAFELQGHQNSVTSVSFSADGRLL
ASGGFDGLIKVWDVTTEELKCTLGEPGYKLGEPGSGIEWVKWHPRGPVVLAGSEDYSAWM
WNADKKDGRPRVFSGHGDVVTCGDFTPDGKTVCTGSNDASLRIWNPVNCAIIREIRGYPY
HTEGLTCMAISPDSAVILTGSTDHKVHMVNISSGKVIRSLTAHTDSIECVGFSPSGQWAA
TGSLDHKLIVWDLQHSEPRNTFLHEDGVTCLAWLNISNPSRYIATGSADGKVQVWDGLAG
GNAAIRTFSGHTEGVQSLSISADGNFLVSAALDGTARVFEIHEFK
>Sgl75301 E3_activity/RING/PHD 35.9 16.8
MGEREVCVLALPSDDVEKPETHVNELKRELGCVVNEAEFVVSPRKKYAKVSSPLNANFDD
ISSEVLDPITIVNDHKNESDYVYENGIENVSSLETAINHHLVDLADRSNDRVNSDETTCE
SSGNSCSMSYCDEVARNRGSNGVSTSQITLEIPKHASTTGIRKITFKFSKSRKEHQSRLP
TSGAQVFFSGLHDGDSVIDSNDELGLDDSVDRFPYNMELKMSKKVFPDTYPTNVKKLLAT
GILEGARVKYISTSGEKEIPGEIRGSGYLCGCSICNYTNVLSAYEFEQHAGGSKTRHPNN
HIFLENGKPIYSIIEELKTAPLGILEELVTDMAGSSVNQGSFQAWKENHQHCSELVQTMR
TFQTKSSSISLSHLSVSSNFMEEKRVVKRRALPSKHVAKRSNDSTSSFTGLQKRSAEGGI
KKRDNDLHRLLFLPNGLPDGASLAYYAKGQKVLDGYKQGNGIVCRHCEHEISPSQFEAHA
GWAARRQPYRHIYTANGLTLHDLAISLANGQSLTPGNNDDMCTLCGDRGELIPCGGCPRA
YHQNCVQLQNAPVGDWYCSDCVERKADVDSSNNSKSIIIKLTRVVKNSEAVWGLEHDFSV
DIFNDRTVIICDQCEKEYHVGCLRDDGRCDLKELPKDKWFCCNDCDRIYVALRDFVVRGA
EFIPSSELIKINLKLLEKGFNEVAENDIQWRILSGKCRRPEHLPLLSKAVSIFRECFSPI
TAKTGRDLIPVMVHGRNISGQEFGGMYCVLLTVKSVIVSAGLLRIFGREVAELPLVATSK
EYQGKGYFLALFTRIEKILCDLKVENLVLPASEKAKCMWVNRLGFKNVSHEKLSMYTSEF
QLTEFSGTVMLEKKVEQIS
>Sgl75367 UBD/UBC-like/UBD_UBC 92.2 0.0
MKLCPREVEKLALHNAGFLAQKRLASGLRLNYTEAVALIATQVVVHSEKFYNFRSSVFID
FEFCSCWKQECGGTDGHWKEASWKLAFAVPEQYPLQPPQVRFLTKIFHPNVHFKTGEVCL
DILKNAWSPAWTLQSVCRAIIALMAHPEPDSPLNCDSGNLLRSGDLRGFQSMAKMYTRLA
AMPKKG
>Sgl75373 UBD/UBC-like/UBD_UBC 112.8 0.0
MKLCPREVEKLALHNAGFLAQKRLASGLRLNYTEAVALIATQVVVHSEKFYNFRSSVFID
FEFCSCWKQECGGTDGHWKEASWKGPSETPYDGGVFQLAFAVPEQYPLQPPQVRFLTKIF
HPNVHFKTGEVCLDILKNAWSPAWTLQSVCRAIIALMAHPEPDSPLNCDSGNLLRSGDLR
GFQSMAKMYTRLAAMPKKG
>Sgl75585 E3_adaptor/Cullin_RING/BCR/BTB 64.2 0.0
MDCGEQRSRRSLKRKLEHDFHENNNHHQCSSSSSSKVNEVCDVSRSPKKQAKKNHKDLLS
EINFHVQILHHCCPLSVSDRIELKRSAQFISELAKNEDMVDLIVDCGAVAPLVKHLQSPP
ENGVSKAIEHDVEKGCAFALGLFAVKSEHQQVIVDAGALPHLVTILKSHKSGCNSRSVCG
AVRRAADAITNLAHENVRIKSLVRIEGGISPLVDLLESSDVKVQRAAAGALRTLAFKNDQ
NKNQIVECNALPTLVLMLRSEDPVIHYEAVGVIGNLVHSSPNIKKEVLQAGAVQPVIGLL
SSCCSESQREAALLLGQFASAESDCKVHIVQRGAVPPLIKLLQSPDAQLSEMAAFALGRL
AQDSHNQAGIVQCGGIMPLLELIDSKNGPLQHNAAFALYGLADNEDNVADLIKTGGIQKL
QEGDFIVQPTKDCVTKTLKRLEEKIQGRRVLNHLLYLMRIADKTVQQRIALALAHLCSPD
HQERIFIDNNGLELLLELLESSDFKQQQDGSVALYKMAIKATVLTPVDAAPSSPTPQVYL
GERYVNNSTLSDVTFLVEGRRFYAHRICLLASSDAFRAMFDGGYREKDAKDIDIPNIRWP
VFELMMRYIYTGSVNVNLDIAQDLLKAADQYLLDGLKRLCEYAIAQDIAVENVTLMYDLS
DAYNASSLKHSCILFILQQFDQLSSKAWYPHLIERIGPEIREFFERVLTKPEVVEMIQT
>Sgl75604 E3_adaptor/Cullin_RING/DCX/DWD 95.9 16.9
MGQYVSRLETDSEESGEYDTSNNGNSSQVLDCSNCLENEISQLTKVKSKPNEHLVKIVPG
KRKRSVSTVNMLAGREANFSGRGRFTSADQCHVASRFLPVRGPWLVDQMNSRAYVSQFSA
DGSLFVTGFQGSFIRIYNVDREWKVQKNIQAKSLRWTITDTSLSPDQQRLVYSSMSPLVH
IVDIGSGATDSLANVTDIHDGLDFSEYGEYGYSFGIFSVKFSTDGRELVAGSSDDAIYVY
DLQANKLSLRIPAHDSDVNSVCFADESGHLIISGSDDNLCKVWDRRCFNAREKPAGIMVG
HLEGITFIDSRGDGRYFISNGKDQCIKLWDVRKMSSNVDNRERARRTYEWDYRWMEYPQQ
AKDQRHPNDQSVSTYRGHSVLRTLIRCYFSPEQSAGQKYIYSGSNDGSVYIYDLVSGVLV
VKLDHHMSSVRDCNWHPNYPMLVSSSWDGTVVKWEFPGNDEMPHSSNNRVIWRQQVI
>Sgl75640 E3_adaptor/Cullin_RING/DCX/DWD 18.8 3.5
MLQLQVLKGHKGPITSLAFDPLNEYLASLDTKETVIYWELQSGNLLHTLKGVAPDTSHDM
SIMNVISWTPDGDFLSVPCLKNDVIMYDRDTAELQYYIRDNQVLIWDVDKRLDIDRQQFD
ERICSMAWKPTGNALAIIDVMGKYEDVLKSKYSNGLLLFDEEEQEQSISASLSDMGEDNF
VESVPHTKKRLRKSSLYEESLEEDIISEELDSHPRIKSHRKPAKNHKECLDGGDGKPKSM
TVQNFSKLQEPFQPGATLVQPGTKCFLCCRMLGSITIMQHDGNSHIEIDFHDTSQCPRVP
AMTDYFGFTMASLNENGSALANPRNGEKNSTLMYRPFSSWANNSEWSMRFEHEEVKVVAL
GTGCLQIARAFGASATIAVDISDEKLAKAKAVGATHTEIIGGAGVDIAVEALGKPQTFQQ
CTQSVRDEGKAVMIGLANSRARGEVDINRLVCRQAYTRAVLSVGGFLNFMLTGSVSAIRF
GVILGGTHDWFLRVDICWTDQNDLQVLKEHHFPKEDSVIA
>Sgl75712 E3_activity/RING/RING 13.2 17.6
MLPWGGFSCCLSAAALYLLGRSSGRDVEALKSVARVNQLKDLAVLLDAASKVIPFIVCVS
GRVGSETPVKCEYSGLRGVIVEETAEQHFLKHNDAGSWVQDSALMLCMSKEVPWYLDDGT
GRVFVLGARGATGLELTVGSEIFEESGRSLVRGTLDYLQGLKMLGVKRTERVLPTGTPMT
VVGEAIKDDVGTVRIQRPHKGPFYASPKTIDQLISNLGKWARWYKFASMGFTVFGVYLIA
KHALGLILERKRRWEINKRVLDAAAKRRDDGKDESGSDSVKRDLMPDLCVICLEQEYNAV
FVPCGHMCCCTRCSSQLSNCPLCRRRIDQSVRTFRH
>Sgl75847 E3_activity/RING/RING 32.4 6.0
MAEETSIPESHKSSCSAPINREDFGKLEFGCEHYRRRCRIRAPCCNRVFTCRHCHNEAMS
SQSNHKEHHELVRRDITHVVCALCDTEQPVQKFCSSCGVNMGEYFCEVCRFFDDETEKNQ
FHCNECGICRVGGRENFFHCPKCGSCYSISLRDNHECVEDSMKNSCPICYEYLFESTKVA
QVMKCGHAIHQECYIDMLKQNQYRCPLCSKSSLDMTSDWEVLDQEIESTIMPDEYRYEVS
ILCNDCNGTSIVNFHILGHKCSQCSSYNTRRKL
>Sgl75977 E3_adaptor/Cullin_RING/DCX/DWD 94 15.5
MGILECRKSESSPKRRKLCKSSMAMENNSSIGLGTKGLIKKHEFVRVIIQCLLSLGFPKA
ASCLESESGISCKSKEFESIESNILNANWDECLKFFNGIKGLSDETRSSAMFLVVRQHLL
ECLNRGDDSTALAYLQKRVSDLRLGTDKVRDLAFDILFSKEKGAGETNDDFYSLRKKLLV
ELEKLLPPPITLPEKRLEHLVETAVTSQIESCLYHNSSGAVSIYKNHNCSRDEIPTETIQ
ILTAHKNEVWFVQFSNNGEYLASSSSDCTAIIWKVVDDGKFTLKHTLQSHQKAVSFVAWS
PDDTMLLTCGNLEVVKLWDVETGTCKHTFGDKGFIASSCAWFPDSKRLVCGSSEAEKGIC
MWDCEGNELKVWRGARMPKVLDLAVTSDGEYLISAFSDKEIRILNLGASTERVISEKHPI
TSLSVSADGKFFIVNLNSQEIHMWDVAGKWREPLKYTGHKQNQYVIRSCFGGLNSSFIAS
GSENSEVYIWNRQKSEPIAILYGHSLTVNSVSWNPKNPHMLASASDDQTVRIWGSIKCKP
GQALDPESF
>Sgl76207 E3_adaptor/Cullin_RING/DCX/DWD 106.8 19.3
MAFECQETSEICLSKKSLNSVVHNNQVKQHFGKTPVYCVKKKTVWRKKGEKSEVLVPKLE
LGIVGDLAVDHPVKLVTADEGDSSGYGRSITDLPPALVSEILNCLDPKELGIVSCVSTTL
YKIASDHSVWKDFYCERWGLPITKSLNLDLADEKSWKELFVEREYRSKTFLGQYRPDFLS
GHTEAVRSVFLLVSAKLVFTAGYDSVVRIWDLEEGLSITSSRPLGCTIRAVAADTKLLVA
GGTNGFIQCWKAVEGVSHLFDLKGSICENSEFRLWEHDGPVTSLVLDLARIYSGSWDMTV
RVWDRALFKCVMVLRHSDWVWSIAPHGTTIASTSGSDVYIWDTNDGTLVDIIPHAHEGNV
YALARSHTGDFIFTGGEDGSIHMFEISNSAEDGIFKVASWVPHSGAVNSLAFEFPWLVSA
SSDGKLALIDVRKLLKSTRSSLMKYRNKKVATIEPPQRMLHCSGCSLFSVDIGADRIVCG
GEEHVVKLWDFSHALERLMRSRAQRAIRLENKMRQRRLQAEMNAKNGKADKCSVAAKKNP
INGDRNCNWHNKRTVNGKMKA
>Sgl76214 E3_adaptor/Cullin_RING/BCR/BTB 73.9 0.1
MSEPSTAVISPTSSRVVTETVNGSHKFVIQGYSLAKGMGVGKHIASDNFSVGGYQWAIYF
YPDGKNPEDNSAYVSVFIALASEGTDVRALFELTLVDQGDQGKHKIHSHFDRSLESGPYT
LKYRGSMWGYKRFFKRSMLEQSSYLKDDCLKINCTVGVVVSSVECPRLHPVRVPESDMGM
QFGMLLENTDGTDIVFNVAGEKFYAHKLVLAARSPVFRSEFLEKLEEGSEEITVTDVEPK
VFKAMLHFIYKDDLVEEAELTPLSSCESHIADLLIGKLLAAADKYGLGRLRQLCESSLCK
CISVNSVGEILALADCHNATELKAVCLRFAAENLAAVMRSDGFEYLKEHCPALQSELLKT
VAGCEDDCSSAGGKSRSVWAQLSDGGDTNDRRVRPRT
>Sgl76231 DUB/USP 239.5 1.2
MTVMTPAPIDQEDDEMLVPHSDIADNHQPMEVVAQAEPANNNNNTNDDNSNNPENQAAED
PQSSRFTWRIENFARLNAKKHYSDVFVVGGFKWRILIFPKGNNVDFLSMYLDVADSVNLP
YGWSRYAQFSLAVVNQIHNKYSVRKDTQHQFNARESDWGFTSFMPLSELYDPTRGFLVND
TVLVEAEVAVRKIVDYWSYDSKKETGFVGLKNQGATCYMNSLLQTLFHIPYFRKAVYHMP
TTENDIPSASIPLALQSLFYKLQYSDGSVATKELTKSFGWDTYDSFMQHDVQELNRVLCE
KLEDKMKGTVVEGTIQQLFEGHHMNYIECANVDYKSTRKESFYDLQLDVKGCRDVYASFD
KYVEVERLEGDNKYHAEQYGLQDARKGVLFIDFPPVLQLQLKRFEYDFMRDTMVKINDRY
EFPLQLDLDRDNGKYLSPDADRSVRNVYTLHSVLVHSGGVHGGHYYAFIRPTLSDQWYKF
DDERVTKEDVKRALEEQYGGEEELPQTNPGFNNTPFKFTKYSNAYMLVYIRESDKEKIMC
NVDEKDIAEHLRERLKREQEEKEHKKKEKAEAHLYTIIKVARDDDLTEQIGKDIFFDLVD
HDKVKSFRIQKQTPFNLFKDEVAKEFGIPVQFQRYWLWAKRQNHTYRPNRPLTALEETQS
VGQLREVSNKVHNAELKLFLEVELGIDLRPIPPPEKTKDEILLFFKHYDPEKEELRYIGR
LFVKATGKPVEILETLKELAGYAVEDGIELYEEIKFEPNVMCEPIDSKLTFRGSQLEDGD
IVCFQKIIPTEIAEHCRYPDVPSFLDYVHNRQVVHFRSLERPKEDDFCLELSRLHTYDDV
VERVARQLGLDDPSKIRLTSHNCYSQQPKPQPIKYRGVDHLSDMLVHYNQTSDILYYEVL
DIPLPELQGLKTLKIAFHSATKDEVTVHTIRLPKQSTVGDVLEDLRLKVELSHPDAELRL
LEVFYHKIYKIFPPSEKIENINDQYWTLRAEEIPEEEKDLAPYDRLIHVYHFTKETAQNQ
MQIQNFGEPFFLVIREGETLAEVKLRIQKKLQVPDEEFSKWKFAFLSLGRPEYLQDTDVV
SSRFQRRDVYGAWEQYLGLEHADTAPKRTYSNQNRHTYEKPVKIYN
>Sgl76242 E3_activity/RING/RING 29.4 9.9
METPSMEDNKKLEEAKLTSAAAFVEGGIQEACDDACSICLEEFSDSDPSTVTGCKHEFHL
QCILEWCQRSSQCPMCWQPISLKDPTSQELLDGVVQERNLRLNPPRNAAIFHHPALGNFE
IQHLPVGVNDAELEERIIQHLAAAAAMGRARHFARREGHRGRSSTQGRQQFLVFSANPNA
QGVPEGGQAEHTQDGSAVTPSLLRIGEEASPQLSSPNYSTQTDMVSSSGTSSTPAGHASP
SDSGRSPGQSSPQNQDRAGPSDLQSFSEALKSRLNAVSTRYKESISKSTRGWKERWFSRN
SPMSDIGTEVRREVNAGIATVSRMMERMETKDNEGPSNDSVPDSSGSSQTRDSGSQHGTD
SVASPGENHLNDNRTQTSCASHSGSN
>Sgl76250 DUB/USP 363.3 0.0
MDSISSEDSTTAPQPIPNDEQRVYLVPFRWWKEALDASTSDSKGVLYSASPSSSFVGPLK
LLNNFFGADFMFNLRREDECSNDNGEVGVSGRDYALVSGDMWLQAFKWHSDHKNEMKRVG
SFSAGYVDISDVYPIHLRLSALREANSLGVKISKKDNAAELFRRACRIFNTEAELLQIWD
FSGRTSQFFVNNSNSPPKDIQRQSDQEMLLELQIYGLSDASKSRDKRDEFSEPCGAVGSS
TSTSTTMNGSNGNNYRFPRTNSSTFSSSSVESGSLGLTGLQNLGNTCFMNSALQCLAHTP
KLVDYFHGDYNKEINHDNPLSMNGEIALAFGDLIRRLWAPGATSVQPRTFKSKLSRFAPQ
FSGFNQHDSQELLAFLLDGLHEDLNRVKLKPYVEAKDGDDRADEDVADEYWQNHLARNDS
IIVDICQGQYKSTLVCPVCKKVSIMFDPFMYLSLPLPSTSMRTMTLTVVDTNGYSLPTAV
TISVPKYGKGEDLIKVLTTACSLQTDETLLVAEIYNHRVIRFLEDLADSLSLIRDEDRLV
AYRLPKATEKDAIVVFMHQEIEEQYVHGKLTSGWKSFGIPLVARICNKISGSDIFNLFMK
LLNPFLMPNEDGLHDLDASESSLHDLDASESSAVDSIVGNTTNLIAVESCNDANVADASE
SSIVDSIIGNTTNLIAVESTNDAKAADGEGVNLVTGDEFLFYLMDDKGILSNSKLEMSDP
VISEDLPKRLNVVVSWPVKKTEIYDTVLLSQLPEIFKSGFLAKRPQENVSLYKCLEAFLK
EEPLGPEDMWYCPGCKQHRQASKKLDLWRLPEILVIHLKRFSYSRFTKNKLETYVDFPVH
DLDLSMYIAFKNSQASCRYELYAISNHYGSLGGGHYTAFVHHGGGRWYDFDDSIVRPINE
DMIKTSAAYVLFYRRVAES
>Sgl76314 E3_activity/RING/RING 27.8 10.2
MVIGGYEMTKMRKSFRESIKALEADIQYANSIASDHKREIDGACFQMRLSYSPAAHLFLF
LVQWTDCYLAGALGFLRILIYMTYEDGKTTMSVYEKKASIRQFYGVIFPSLQQLQPGITD
VEDKKQHEVCDLRYRRKDVYENNKSIEVEKEIEEECGICMEINNKVVLPNCSHSMCFKCY
KDWSARSKSCPFCRDCLNGVKSSDLWIYTDDCDTVALPVIMTENLNRLFIYLDKLPLVDP
YPGSATYDWHIG
>Sgl76319 E3_adaptor/Cullin_RING/DCX/DWD 62.3 5.4
MSPRTRRAASPKFVIERDEDSEVSSSDEEEVEDEDEENGVNNSEDDEVVEEDDEVEEKFE
DNKKTEKKPITISLKKVCKVCKKAGHQAGFQGATYVDCPMKPCFLCKMPGHTTMSCPHRI
ATEHGVVPAPHKSTRHSVYYVFERQLRPQVPAIKPGYIIPDHVRCAVIKYHSRRVTCLEF
HPTNNNILLSGDKKGQLGVWDYYKVYEKRLYSNIHSCLLNTMRFSSVNDGTIFGASSDGT
ISCTDLETGLSESMMDLNPNGWHGPKSWRMLYGLDINSEKGLVLVADNFGFLYMLDTRTK
GKVGEAVLIHKKGTKVVGLQCNPVQPDLLLSCGNDHFARLWDLRKLEAGASLGNLAHGRV
VNSAYFSPHTGSKILTTAQDNRIRVWDSVFVNMETPSREIVHSHDFNRHLTAFRAEWDPK
DTSESLVVIGRYISENYNGVALHPIDFIDVSTGQLVAEVVDPNITTISPVNKLHPRDDIL
ASGSSRSLFIWSPNDKSEDVQQRDKKKTIVFCGKGDKKHKSKLGDESDESDDELFKSKGK
TSKAKSITLKKVKR
>Sgl76329 E3_activity/RING/RING 14.8 9.5
MEEQAQITTPMLQPPINDDFAPSSSSSPSPALQLEESEQTEAYIEQDQQQQLNDMPWYWH
WQPNLVFERFNVTVCSDDVRNDAWSCLIMLLTFWFFASVVLILGLYGSFDLQLGPNCSFL
VETNPFFVHSIQARQLNDQTDGLMLYGFHESPALDVETTWSQNHTVPIEPTIHKEWAYYL
NAGSKVYVSYDVKYPDSSTLFLVIAQGRESLRNWIYAPSYNTTMSWNKIYGSGQIAQDIK
ESDTYFVAVGNLNLETVEVYLNITIKSFLYNTTKANFKCSLSNRVCDFGLIFLKPNAAVL
TSPGLSQVNSDINWYIQVSYEPQWITYCGGSCILAALIFALLRYCSNDNQTGNEVDERLA
VREPLLSPKNNDHTSWGSSYDSIPSDDDQDSDGKMILEGSCEGKVLKEGEIHSQTTRRLC
VICFDAIRDCFFLPCGHCAACFSCGSRQVFVIVLYSTV
>Sgl76344 E3_activity/RING/U-box 74.4 0.2
MTSKQPPSPLETLNRQLELLVNSNDTFPFEPPRRFTSYAGDLHRITGNLLRLPNDVVLSS
PSIVTAVKGISVDLAKAYETVSVYKERSKIYVLINSRCLCQSLRERTVAIAGWLALLVTV
LHTFPDLRKKVYDLSRDMKLPHFALTENEDRVYCTLQKEGQGKPITRPVQSAIIMDLARA
LGISPDNHAELSEHVKLLKNDVARSNSVSERRILMSLQRILDSWFVEPNISALSLDFDLE
DDSQILPFKNFLCPLTKEVMKDPVVLESAQTYERTAIEYWFERCLEDGRDPTCPVTGKVL
SSLEQKPNIGLAGAIEEWINRNVDIQIKSAVKHLSMDPPPVDGLERVLDTIYKISEEHPS
SRYKIRNAGVVVLIIKVLKNFSKSTIYSLKTKALMALLSMAKDEDCKAIMIGEGITKLAI
NSLVAGSIEKEKEKENALMLLIELSNNEAYRARIASEKGAFLLLSSMAESLESPALSKLA
EDILKRLEVMDENVEHLAAAGRLEPLLSRLCEGSHGTQIEMASLLGKMTLTNSNKEHIAR
RCATVLVEMLLKLETRTASLHALCNLSSFDDNATVLVEASVLPVITDIVLESQDALPEQK
ELAAAIIANIVSNPGHWELAEVDKNGNSMLSSFIVSRLMQLLSQLTPQCHVYVLRILCGI
LSSPKSSEQVATEIKSGDGIKTIMEYLEHPETEHRIYALKLLRMLSESSGGVLFNEFKCQ
NKLVFLKEKLQDNMPTNSEQSDVACILANLPLSEEEVKTVLGPGFLNWTVMTLKENQRIP
SGRASRSSSSLLEGLLGLLLHFVRSIDAQILTWVKEHHLIVIFREQLIYLSQPRCKQLAV
VGLRHLSESGRSLASDGESDPLPPQGLCSSMVFICGRAIPDINSTCPIHNAPCEEESELC
LLKSYCIKPLVDLLSDDQTEVQIAAVEALSSLIPETSHNFRAAADELDRLGVVDAVANLF
IEIRPGELQEKAIWMVERLLRGENTSQRFAINQNLVSALGEALKLGNANTRKLAQDALTN
LKQLSGASGKISGPIRAWR
>Sgl76345 E3_activity/RING/RING 35.1 3.6
MDAEDLELSTISSDGFEVTSYAFEHASASNNHVHRPVDDLFNVMLCYEYNRIPNNVARYL
SFMMVKERDQSDRSDIVTDVINNLDEFDVDVNVYPCTIDVVQSSCEIFLKQVRDLGRRSL
AMIVKIIVFERMEEDLVGIAPDEEEQEPEPMMAEEEFEEEPMTGEHIALMVESTRRLKSL
EGIVIIVGNDGLDGVKVTRRDQFGTDMMGPCSICFKDFKDQENNGGESDDSKHNKTGLLV
LPCSHVFHNLCLLPWVYKGKGTCPNCRFNFLKNL
>Sgl76354 E3_activity/RING/PHD 36.4 34.0
MPYTITSMPDSGRHTKRRRLLPYNKFHRDDNVEVRSIEDGFQGSWHAGVIINAFEDGYPE
VRYNHLLHDNEIDYLTEIVEVSSTDRILSTSKTCERGRIRPIPSSGKLTATNLRYGLCVD
CYYNDAWWEGVVFDHEDGSSERKIFFPDFGDELITDVKQLRLTHDWVEATGDWNPRGNWL
FLEMFEEFERDGFIPVSLKQLWYDMRERKEFGRIGEWPSPDKPLWQKLIKQVIEDNLKLT
VDALLKGCVSSGDMSNNCEAAPLLDPTMNPDPMLVDSLAVVAFSAGISGELKSENEAAFT
TVSKSRENAELATELLESTPTSNQLVPVQPKVLSVTCPDQKGFESHTIPDSKVLSNFKSD
AKKKLHRNKRRLHPGESLFDLTPLFSPESMSTYVQKERPGYTMTAKVRSHLLFMGYKMEH
QYEGRNVYYTSPEGRKFYNLRSCLTFEIAKAERSSLSVEDIPSGMVLSPGDLKCTPRLKI
SNTSKGRGQKRKEIVLNQNIEPKFCPEAIIKYLRSSKKRHRLKNCHNKLQDEVRGHLSFI
GWKIQSILRKGREEWRYDSPTKRTYNSLVSACKAIVEGVEMNTSSASEDINCEKSKELSG
GELPLPDKEVSAFFLSKKWSRKFPRSHKKYKSGKLQRRRHIGHPIHSTPSLHKNGGQGQE
AGVNAKRRSSRKVSTAFLSKKEKALGKVKHSSDKSDLRVLRSSKRVRQAGPSISSQAPRT
VLSWLINNGVVLGREKVLYYRQGDDQPIAEGRITSCGINCNCCKQVFTLRGFEAHAGSTC
NQPAANLFFCKDGKSLVQRQLDLMHQKIQSLSREPLEKSRGKRPKSWSDHVCSVCHYGGE
LMLCDRCPSSFHAGCLGLQDIPEGDWFCPSCCCGICGESYSDENTECSTERTLACYQCER
LYHAQCVKERDVATFDVHPTENWYCSKMCEKVHWGLQQLLDKRFCVGHDLTWTLIKPMDY
QDIHHDDCDVVALSENYSKLNVALEVMHECFEPVKEPRTKRDLVEDVIFCRRSHLNRLNF
RGFYTVLLERNDELITVAVLRVYGDKVAELPLIGTRFKHRRLGMCRIAVQEIEKILINLG
VKKLVLPAAASVLNTWTNAFGYIPVTKSERSEFLSYCFLDFQDTIMCQKILKKLPLPLPT
LSRVLPGALNQVHQNIEGTSIIADPEGSNAISEVFPRRST
>Sgl76427 E3_adaptor/Cullin_RING/SCF/F-box 15.8 0.0
MANLPFELITSILTRLPVKSLVRFKCVSKEWNSLISNPHLIALHLTQSLSSNNRLLILNY
GTHLESTPLLLSSETEVKTRRFDLPACFSGFEVSFCGSCNGLVALVCKKITVDNEYNDVV
LEVVLWNPSTNSHFIVPHAYENDDLLSTEFLGVSFGFGYDGAKDDYKIVRIVDYFHSNNS
STDDDDGNDNGDGVDDVDGNGGDGDGDDDDGGDDEGGDGDDDDGDDDSDGEDHRCKYGFI
FRDIMVYSLRDNCWNKIHVAFFGDKMEWFCPGAVINDHLVHWIFWNYRKRKPILRLFNLS
TFTWTKLALPDFRGNNNGNHNKTDCPSDDDDDDNDDGDLFDHGFKPTDFVVLGVLDECLC
LVTRICPEFDNVYVWVMREYGVKESWTKLFDVTEASVIGPLLSTPLACCKGDDELLLRKH
NEDGFCWYDRKGKTVKAAPKLPSCNLKLHDVKLCVESLVPLAKIDC
>Sgl76452 E3_activity/RING/RING 37.3 6.6
MSFVFRGSRGDIENGLSGIIPERRSVRIHPVRPVNSNSLAFLVTVLLLFTILNTHQMSPN
FLLWLVLGVFLIATSLRMYATCQQLQVQAQAHAAAASGLFGHTEFRLQMPPSIALASRGR
LQGLRLQLALLDREFDDLDYETLRALDADNVSNTSSMSEEEINALPVHKYKVTGPEGEDL
QPQEASSTSTSSEAKQEAHNGKSSEEDLTCTICLEQVKRGELLRTLPCLHQFHANCIDPW
LRQQGTCPVCKLKVGSEMQEVLDSNAANASDMV
>Sgl76483 E3_adaptor/Cullin_RING/SCF/F-box 21.6 0.2
MSDLLPTIPCDIIFEILGRLPVKSLLCCKCVCKDWYNLINTSTFVDHHLKQSINDSDHLC
HRQRPFVFAWGKSLYLGEDIEFPKKLIKLNLFKDNNNNVIEFNDAHIIGLCNGLVCLRLG
SNPKHFLICNPLTRTFKVVVVAHGEWEEDMNRNLWYPVYGFGYDTKTDDYKIVVMTMGRD
RHIWIYSLKTNSWKKGCSDRLHQPPFQEKMYHNQLAYGIFGHGMLHCIVREVAIVSRDGY
TYQELPQISRFNLSSEDWDYDLSFPDHSSYDPSTHMKVDLRMLDGFFCIATYDFRENLYI
WIMKEYGVKKSWTKLHNCDLSIYNLIAFSRTRPNGLWFNISSQGGLVWYDPKQGTKELFE
YDIPFKNVFHYEVTLCAQSLVSVPGSSYLID
>Sgl76531 UBD/UBC-like/UBD_UBC 114.4 0.0
MASSPSQGSLLLQKQLKDLCKNPVDGFSAGLVNENNLFEWSVTILGPPDTLYEGGFFNAI
MKFPHNYPNSPPSVRFTSEIWHPNVYSDGNVCISILHPPGDDPNGYELSSERWTPVHTVE
SIMLSIISMLSSPNDESPANVEAAKEWREHRGEFWKKVSRCVRRSQEML
>Sgl76532 UBD/UBC-like/UBD_UBC 115.2 0.0
MASPSQASLLLQKQLKDLCKNPVDGFSAGLVDENNLFEWSVTVIGPPDTLYEGGFFNAIM
SFPQNYPNSPPQVRFTSDIWHPNVYADGRVCISILHPPGDDPNGYELASERWSPVHTVES
IVLSIISMLSSPNDESPANVEAAKEWREDKEGFRKRVGRCVRKSQEML
>Sgl76542 E3_activity/RING/U-box 119.4 0.1
MEDDKEAQLLNKLIDRINEIASISDYRPPVKKQYCNLARRLKLLTPMFEEMKETSEPLID
DAFENLVAFGDSLNHALDLLRFGSSGSKIFLALEREQIMKNFDEVTSGLEQALDGISFEK
LEISDEVKEQVELVITQFRRAKGRVEAPDAELYEDVSSLYNSSNDTAMDPAVLRRVAEKL
QLMKIDDLTQESVALTEMISTADGDSDAKIEKMCNLLKKIKDFVQTENPDLGSSAGETNV
ASNCAGQTTADGSPKSLVIPDDFRCPISLELMRDPVIVSTGQTYERSCIEKWIGAGHNTC
PKTQQTLQNSSLTPNYVLRSLIAQWCEANGVELPKRPGSSNPNRSTSACSAAERSKIDEL
LRKLHSGNPEDLRSAAGEIRLLAKRNADNRVAIAEAGAIPLLVDLLSTLDSRTQEHAVTA
LLNLSICDDNKGSIINSGAVPGIVLVLKKGSMEARENAAATLFSLSVVDENKVTIGASGA
IPPLVMLLSEGTQRGKKDAATALFNLCIYQGNKGKAVRAGIVPTLMKLLTEPGGTMLDEA
LAILAILASHSEGKAAIGSADALPVLVDVIANGSPRNKENAAAVLVHLCSGDPNYLTTAQ
DLGIMSPLLEMTQSGTDRGKRKAQQLLERMNRLLEQQKQAQAQAEAEAQAPPPPPPPTAA
EE
>Sgl76555 E3_activity/RING/U-box 77.9 0.1
MQLLTPLPFPLPLPEPTFDRYSRSSSSSMASYGAELERLNSGLAHIHEDEDEDENERNQR
LMKKKRNKVVYVAVGRSMEKTVSLLQWAFRNFHNSEFCLVHVHRLSPFIPTLLGKLPATQ
ASAEVVAQYRNEEREKMRKILCSYMDICCKAKVKASSIITEDEEVHKGLINVVMKHGMQK
LVMGSVPDNCFNVKKSCRTANYAAKNAPLFCEIWFIHKGKHIWTKEASESVTLPTICQED
GPTTDRLRSKSFPYNKSEHLYSPINLQSRSSCPSIQYSGMKDMNQNEPSEEDLLLPSPVN
PCNSGYGQSSISYDSASCTSSMERGDSSDPDFRLEVENLHGQLLEAKAEVETAKAEAVLE
SLKRENLEAEAVKAMKKVKDLECALNYETEQRKEAEDSLQSLVHKQERILQEKLQVSGEI
QKTNKIVAVLENRVQEANRRCNEADGELNLIRDSIPSLQKEKQKIERQIMEAERWLEKWR
SRRQIGGTNCHGYVGLLNDVPDLVEFSRSDLQTATCDFSDSFKLFEGGCGNVYKGELLNR
TVVILRLHAHSIHTTHFQKEVQVLGKLRHPHLVTLIGACPEACSLVYDYMPNGSLQWHLF
QKSNNAPLSWKIRTRIISQISTALLFLHSSHPEKIIHGDLKLECILLDSDLHSKICDFGI
SRLLLQDTLHLPGIRRYPEPLGAFPYRDPEFHRIGKLSPKSDIYSFGIIILQLLTGQPPV
GLIANARRAVSGGNLNSVLDSSAGEWEPFVAEKLAGIALSFCEQNSRDRPELTPSLVKEL
QQLHISKERTVPSFFLCPIRQDIMCDPQVAADGFTYEGDAIRKWLENGRETSPMTNLSLD
YLYLTPNNCLRQSIQDWLCRY
>Sgl76565 E3_activity/RING/RING 44.9 5.0
MDPQTYMYIDIAIAISMLVFASIFTKIIADVLVNARDDPALPRELIVEHEYDLEAAATVL
AKIDDKKIAEIAENCSDCAVCLDDFDDDDEEGNDNGIKVLRQCGHRFHSHCIQQWFSRGH
LNCPMCRNPVIKHVL
>Sgl76668 ULD/UDP/UBQ/UBQ_PIM 53.5 0.5
MENKGSSVEEVKLQIKFGGQTISLFVSVDSTISDLKSLLQSSTNVLPRGQKLIHKGGILI
DSKTLRSSGITNGAKIMLMASQGLHQGEGPKLKDAPVVPNHRRVMNSDRMSSKPIQETPV
EKNRTERWKIMGVIGLSDHHLKAIPDEVWDCGSSVRVLDLSSNYIRDLPIKIGTLTSIQK
LILNANDISDDSINWQGLTELKCLTHLSLNQNHLTYLPSSVGAITSLEHLHVAGNKLESL
PTEIGLLTRLEILKVNNNRLSAIPTHIGDCSALIEVDISSNLLLELPESFGNLQKLKALH
LSNNGLKSLPSTLFEGCVRLSTLDLHGTEITMDMLREVKGWLEFDERRRMKYQRQLDFRA
GGSAEFDEGADKKN
>Sgl76669 E1 558.4 0.0
MLPRKRAVEGEVVDSTTTSSSSSSSAFKKTRVEGSSSAVNSVGNTSNNLNSNNNLSVGSD
DGVVTITMARGDGNPQDIDEDLHSRQLAVYGRETMRRLFGSNVLVSGMQGLGAEIAKNLV
LAGVKSVTLHDEGMVELWDLSSNFVFSEDDVGKNRALASVQKLQELNNAVLVSTLTTKLT
KEQLSDFQAVVFTDITLDQAIEFNDYCHSHQPPIAFIKTEVRGLFGSVFCDFGPEFTVVD
VDGEEPHTGIIASISNDNPALVSCVDDERLEFQDGDLVVFSEVHGMPELNDGKPRKIKNA
RPYSFTLEEDTTNYGMYQKGGIVTQVKQPKVLHFKPLREALSDPGDFLLSDFSKFDRPPL
LHLAFQALDKLVCELGRFPNPGSEEDAQKLISLANNINEDSGDNKLEDINPTLLRHFAFG
ARAVLNPMAAMFGGLVGQEVMKACSGKFHPLFQFFYFDSVESLPTEPLEPSDLAPRNSRY
DGQISVFGYKIQKKLEDAKVFVVGSGALGCEFLKNLAMMGVSCSSEGKLTVTDDDVIEKS
NLSRQFLFRDWNIGQAKSTVAATAATSINPQLCVEALQNRVGTETENVFNDSFWEDLSVV
INALDNVNARLYVDQRCLYFQKALLESGTLGAKCNTQMVIPHLTENYGASRDPPEKQAPM
CTVHSFPHNIDHCLTWARSEFEGLLEKTPAEVNAYLSNPGDYASAMKNAGDAQARDTLER
VLECLERERCKTFEDCIAWARLKFEDYFANRVKQLTYTFPEDAATSTGAPFWSAPKRFPH
PLPFSSSDTSHLHYIMAGSVLRAETYGIPIPDWATHPKKLAEAVDKVMVPDFQPRKDAKI
VTDEKATSLSSSSIDDGAVIDELISKLESIRSNLQPDFRMKPIQFEKDDDTNYHMDLIAA
LANMRARNYSIPEVDKLKAKFIAGRIIPAIATSTAMATGLVCLELYKVLDGGHKLEDYRN
TFANLALPLFSMAEPVPAKVFKHRDLSWTVWDRWVMKGNPTLRELIGWLKDKGLNAYSIS
CGSCLLFNSMFPRHKDRMDKKIVDLATDVAKVEIPPYRRHLDVVVACEDDDDNDIDIPLV
SVYFR
>Sgl76678 E3_adaptor/Cullin_RING/DCX/DWD 14.1 18.0
MEFTDAYKQTGPCCFSPNARYIAAAVDYRLVIRDTLSFKVVHLFSCLDKISYIQWALDSE
YLLCGLYKRPIIQVWSIAQPEWTCKIDEGPAGIAYARWSPDSRHILTTSDFQIRLTVWSL
LNTACVHVKWPKHSAKGVSFTRDGKFAAVCTRRDCKDYINLLSCDSWEIMGVFAVDTLDL
ADIEWSPDDSAIVVWDSILEYKVLIYTPDGRCLLKYQAYESALGVKSVSWSPCGQFLAVG
SYDQMLRVINRLTWKAFAEFMHLPNVRGSSCAVVFKEEDEEPQLDIAGLSLNGDPYDSNF
ADISERQIGVRYEVAELPITLPFQKPAMDKPNPKQGIGLMAWSSDSQYIYTRDDTMSTTL
WIWDMQQLQLAAILLQKESIKAAAWDPKSCRLAFCTGSTHLYMWTPSGAYCVIIPLPHFT
IVDLKWNSDGTYLLLKDKESFCCAAVPILAESTDYSSDE
>Sgl76701 E3_adaptor/Cullin_RING/SCF/F-box 12.8 0.0
MLRKKNKDETADDLISALPDEVLLYMLSFLDVKTAGRTSILSKRWRYVWTYIMDLDLDSM
TWECRSAATFGKSVDQIVAANQAPYLNTFRIHYDEMEILLYAADFLRWVKFALSKEVRNL
EFRLGFWNCIMQSTNIFSN
>Sgl76767 E3_adaptor/Cullin_RING/DCX/DWD 90.1 19.0
MTEKGKGGKSGKSGELTVDEKYSQWKSLVPILYDWLANHNLVWPSLSCRWGPLIEQATYK
SRQRLYLSEQTDGSVPNTLVIANVEVVKPRVAAAEHISQFNEEARSPFVKKFKTIIHPGE
VNRIRELPQNTNIVATHTDSPDVLIWDVENQPTRHAVLGAHSSRPDLILTGHQENAEFAL
AMCSCEPMVLSGGKDKLVVLWSIHDHVSTLATEPGSAKSNSAGTNIKSATKTGDGNNGNA
DSPSVGARGIYKGHDDTVEDVQFCPTSAQQFCSVGDDSCLILWDSRIGLNPVAKVEKAHD
ADLHCVDWNPHDENLILTGSADNSVHMFDRRNLTASGVGSPVHKFQGHNDPVLCVQWSPH
NRSIFGSSAEDGLLNIWDYEKVGKMQTESGSKVSEYPAGLFFRHAGHRDKVVDFHWNSTD
PWTIVSVSDDCSSSAGGGTLQMWRIIDLLYRPEEEVIAELDKFRSHVTTCPPLT
>Sgl76797 E3_adaptor/Cullin_RING/DCX/DWD 17.7 0.0
MGEAEIENGNGKIDEVEDTQVKNPNNGGTLVEEEAAAEEIVGPVPPPQRRAKRPLQFEQA
YLDSLPCANMYEKSYMHRDVITHVAVSLADFFITGSYDGHLKFWKKKPTGIEFAKHFRAH
LGPIEGLAVSYFAFGISDCI
>Sgl76811 E3_adaptor/Cullin_RING/DCX/DWD 80.5 28.4
MIAEKPSWIRHEGMQIFSIDIQPGGLRLATGGGDHKVRIWNMKSVSKDSETDDQTHRILA
TLRDHFGSVNCVRWAKHARHIASGSDDQVILIHERKPGSGTTEFGSGEPPDVENWKVVMT
LRGHTADVVDLNWSPDDSMLASGSLDNTIHIWNMSNGICTAVLRGHSSLVKGVTWDPIGS
FIASQSDDKTVIIWRTTDWTLAHQTEGHWAKSLGSTFFRRLGWSPCGHFITTTHGFQKPR
HSAPVLERGEWAATFDFLGHNAPIIVVKFNHSMFKRNFSNAQDNKTSSAGWANGASKTGG
KEAQPYNVIAIGSQDRTITVWTTASPRPLFVAKHFFTQSVVDLSWSPDGYSLFACSLDGS
VASFHFEVKEIGQRLTDDELDELKRSRYGDVRGRQANLAESPAQLLLEAAAAKQNTSKKV
AVGVQKQQVASKPASDLGPISKVSDSHLDNGNKNGVSSDGLNKVAASARVSSPVKQKEYR
RPDGRKRIIPEPVGVPPQQENITAMSQNEVLDSSLAPSDVRKDVNPAQVRRIIGAGSDVK
ERSGVTAKASFSDSLVVEKVPVASGRDGGVLVESSASAKASSSLAACKTTLTIKVVDKKE
GSDAMPISLEARPREHAVSDIVGMSNMSLVKETEIVCSRGSETLWSDRISGKVSVLAGNA
NFWVVGFEDGCVQVYTKCGRRAMPTMMMGSSAVFVDCDECWKLLLVTKKGSLYLWDLFNR
SCLLQDSLASLITADPNASSKDAASIKIISAKLSKSGSPIVVLATRHAFLFDMSLKCWLR
VADDCFPASNFASSWNLGSSQSGELAALQVDVRKFLARKPGWSRVADDGMQTRSHLEAQL
ASALALKSPNEYRQCLLSYVRYLAREADESRLREVCESFLGPPTGMGGSASSDTNIAWDP
SILGLKKHKLLREDILPALASNRKVQRLLNEFMDLLSEYGSAETHTEQTSLISSMVATRA
TERIDMMPSLNDMQVDPPVVDPIMDLLPQKSKQGDATPSTRDHQMDGSTIPPDQVIKVGL
GEDRVTINPAKDDVNLIMTKDQANPLPWYTEPMNIDMPKTEKVVVALPAKDQNF
>Sgl76888 E3_activity/RING/RING 37.7 12.5
MDDFNMSPPTMSSAASKAVSISAQVMIIAIVILCVVIAFCLCLHLYVRYCWLHNTEDPNI
VSWRRRLARQQRPQSSAATHRRGLDAATLQSLPTVVYNPKDFKEGLECAVCLSELSEGEK
ARLLPKCNHGFHVECIDMWFQSHSTCPLCRNSVVSGDSNNNDHNDVEVQDNDDFYSSDSS
ESEYDHDNDSRRATELPVYPTNVLFWGNETQVRSFGQAADNDASSSAGSSSGVSRPRNTD
EVVIEIPSHHEFCEDCLSLPPPQEEPKTPVMTRLRSLKRLLSLGKRVGVAPLPHGSSSSS
CEVDQNHQQV
>Sgl76895 E2/UBC 95.6 0.0
MAEKACVKRLQKEFRALCKEPVSHIVARPSPNNILEWYYVLEGSEGTPFAGGYYYGRITF
PSEYPFKPPSIRMTTPSGRFMTDTKICLSMSDFHPESWNPMWSVSSILTGLLSFMMDKSP
TTGSVSTSVEDKQFLAKNSLAFNCKNPTFRKVFPEYVEKYQQQLAEQAQLDALALRAKEE
SSALKSETLGNNMQGNLAEAEGGNRRKNRKQPVPTWVLLLVFSIFGLVMSLPLLEH
>Sgl76912 E3_activity/RING/RING 11.1 25.1
MASSNIDLYVDETYLLTLLNDDEQLIPISDEKYAQELHVQEALYSSSSSSSSSSSSLTLF
AESSSFFPEIFECPKTEDDEKQSIEENRGKSKKQEDREVGESAKPQLNFCGICMDYKQNP
EIFKGLINCNHDFCTDCIIKYVASKIQENIAMVECPNPKCKQVIEAESCSSILPKEVFGR
WEEALCEAMILGSLKFYCPYKECSVLMVDDGEEVRESECPSCRRLFCAKCKVPWHAGVTC
VEFQNLEKNERANEDIMVMKLANDKKWRRCSNCRIYVEKIDGCLHMTCSLGYTRQVNNNL
QFIAKMPSLVNRLINFCV
>Sgl76914 E3_activity/RING/RING 24.5 3.1
MASSNIDLFVDEAYLLALINDEPLPISDEKYAEELHLQEALFNSSSLPRAPVFSYPRTED
EKHSIIQTREKGESSQTHPIFCGICMENKQNPKIFKGLTNCNHAFCNDCIVKYIASKIKE
NIAMVECPDPKCKQAIEPENCSTVLPKEVFGRWENALFEAMIPESQKFYCPYKDCSVLMI
DDGVEEVGMSECPSCRRLFCARCKVNWHDGVTCDEFQKLGENERAKEDIMLMKLAKGKQW
RRCPSCKIFVEKTEGCHHMKCRCRYDFCYHCGCGWSETHQSQCLS
>Sgl76984 E3_activity/RING/RING 36.5 7.8
MDTDVVMVPAGEGSSVGGPSSKKPKRFEIKKWNAVALWAWDIVVDNCAICRNHIMDLCIE
CQANQASATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNSEWEFQKYGH
>Sgl76997 E3_activity/RING/RING 13.7 12.3
MSAGDQAVAAIAAQVALAGDGALLGLALAYVAFRSFQKYAATSSALRKISDAPSVHVSDL
RSLITDESDAGDKDGGERVAKVLVVVRGLVESKSIGKGSWKSLWPDVIVSENSGVRGVVL
QRSQKCIYNEWRGLFGWYPDVRSILARAWREAGSTSLRSVPFVLIDDCRQQLQSDYVVVD
LDESNHPLPLTTVYQHMQPIQASPYTFLQALTGHEYPVGLLDVEKILPIGKEITAVGICS
SKNGVLEIKSCRDLPIFLSEWTKDQMVIELSSKTKILLWSGVIVGSVSIAVLGYAIVRNW
NKWKQWREQRRTQQENRAALSGEGGSSSSNEFEVAEEEEVEDVPEGQLCVICLMRRRRSA
FVPCGHLVCCQRCAFSVERDLAPKCPVCRQTIHGSVRIYDA
>Sgl77023 E3_activity/RING/PHD 34.4 9.8
MDGGQYNPRTVEEVFRDFKGRRAGLIKALTSDVEEFYQQCDPEKENLCLYGFPSEQWEVN
LPAEEVPPELPEPALGINFARDGMQEKDWLALVAVHSDAWLLSVAFYFGARFGFDKADRR
RLFNMINELPTIFEVVTGTAKRLVKDKYAAPNHTNSNSKSKSNPKSGSKYSKAPPQPKEE
EEGLEDDDEDEEDPGETLCGACGETYASDEFWICCDICETWFHGKCVKITPARAEHIKQY
KCPSCSNKRARP
>Sgl77070 E3_activity/RING/RING 13.1 6.1
MQLALNDGLQEVSSETEPILSESLIVEESQETTLCEIKTGDGDISVVADVDADEYCTLVT
SEQPQCRICLDSEGEDLIAPCYCKGTQKYIHRSCLDNWRSTKEGFAFAHCTECRARFLLR
PNIPSDRWWLRLKFQFLVARDHVLIFIVVQLIVAMLGVLVYRYYGEELREMFGYRVHPYA
FYITAVLAIILIGMLYGFFIAIICGQRISERHYHVLAKQELTKEYIVEDRESRDVPELDP
CHESELRMLGLY
>Sgl77077 E3_adaptor/Cullin_RING/SCF/F-box 14.5 0.0
MEPQQQSSETPINNLVQDHLLSILLLLPINSIISFALTCKKFNSIASSNTFWESICSREW
GPTCVDALKSSYLASNYGGNQLPWMKLFQQVAQLNSVSCLKLSYPISDDSVPCPRASHSL
NYVSNCLVLFGGGCEGGRHLDDTWAAYLGYDYKTILKWQKVTSGLPSGRFGHTCFVTGDF
LILFGGINDHGVRQNDTWVGNIVLSETFGITLLWRLLDVGSAPAPSPRGAHAGCCMDNRR
MLIHGGIGPDGVRLGDLWILEMSENFRHGTWHEILTHPSPPPRSGHSLTYLDNRRTLLFG
GRGLGYDVLDDLWVFDASEGEDHPQWSRVQFDSSSTSWGSDLPRVGHSATLVIGGKLLIY
GGEDSLRRRKNDFWLLDVNSIKKHPLCSRMWQRLKSSGYKPKSRSFHAACSNHSGHLVYM
FGGMVDGILQPAEPSSLRFDGEVFAVDFCLNFR
>Sgl77099 E3_adaptor/Cullin_RING/DCX/DWD 58.1 6.2
MNTPIIDPLQGDFPEVIEEYLEYGVMKCIAFNRRGTLLAAGCSNGNCVIWDFETRGIAKE
LQDKDCNAAITSVCWSKYGHRILVSAADRTLILWDVATGEKVAQTTLEKAPLHARLHPGS
STPSLCLACPVYSAPLIVDLKTGTITVLPASVSDGGDGQSAPSRNKVTDDSAPQTPACFN
KHGDLVYLGNSKGEIFIIDHQKAQVRAVVSVAGGAVIKNIVFSRNGQYLLTNSSDRIIRV
YENMLPTKDSLKVLDEMSDTVNDLSGVEKLKVIGTKSLVLFREFQDSVTRIHWKAPGFSG
DGEWVIGGSASKGEHKIYIWDRAGHLVKFLEGPKEALIDLAWHPVHPVVVSVSLTGVIYI
WAKDYTENWSAFAPDFKELEENEEYVEREDEFDIMPETNKVKESEVNQDEEVDIITVELE
STFSDSDMSQEELCFLPAIPSPDAPEQQDKSAGNSLKLVDSNHSASPLSAGAVQNGHAMN
HESSPVEGIDFSTADDISGGRMKRRRKPSEKVLESQAEMVKKPVKKAKPSAKSALKPKDK
SLVDEDNGVSVSMDEVSDDYYR
>Sgl77118 E3_adaptor/Cullin_RING/SCF/F-box 15.2 0.0
MCNCVVGANIISGDLTLPSLPQIHFLLYQTANRDPMTNVIDYVTSYDNPFGKLPDHLLVD
IFIRIPVTDWAKVSCVKKQWANIFQGECLWQAALAKTYPFAGLAKRWPGPIPRGLSKRRF
TALYISRHILSVDDGMDEIVGHTYLFLKEQLEISTMPPPSTILHGTIIDQFIACGNSRER
AHELASLIWLAVIDNLEEDERTFHLLRRLAREGNVFLPFPYSRSNKVLWRIFEKLFTDFR
DCLNYADYCDLLASAKSRFQPIPSTWLGY
>Sgl77132 E3_activity/RING/RING 16.5 17.0
MVGYQLVSSSTSHESLKVIEADIQHANMLAASIPRNKSGNWLQMKLVHNDLAPLILYLLQ
WFNCSCTCLLPSCLNLFYVVIYKVNADGRPDMMSYGRRATLKEFYAIILPYLHRLHGSMS
ELNDGANSSNSSDLAIRKIAQESRQLSDIDFDREDECGICLEPCTKVVLPNCCHSMCINC
YRDWNLRSESCPFCRGNIKRVQSGDLWVLTCGTDVVDPKTVLKEDVLRLYLYINSLPKDV
PDALFLMYSEYLI
>Sgl77171 E3_activity/RING/RING 31.5 8.0
MAERHHQPSTSGVRTNSDFMDVDEVLVVPDTPDRVSRQTKNIRSVEFSSRSSGVASRVTR
DRMNRHFGDSARSAGMHSRGDVGVKPQIHDVNCTNVPSSSFSNAPMSSMAVGNTLTTHKD
IYHRNRQHLEDGKVSKSSSIKSSHHHKRNEDPVLVEFCEIAESPTSTRGNLGVRMRNKDD
LLPNRSSSLHTAGNFSKPNRNSYKEKDKVDYDNPVNCDTHSVKQNDNNCLGTSDNNTGKG
LFVPSHTFRIPRTRTTEKKRLVRNGCISPQNIANAKRLEETSGNGFENTECAVIAGGSHP
VTEVNEVTSKQSAASRAKGKGLLIHDSSSRGYAGRRSHAGYSTGERCKGKYPEKDCVSVQ
DTDVNSNKVVDKSTSSIPSSSFVQKPAVSEGQRQRKHGLSSGSPLKSTEVICLNSGAESS
TKKSVRDHGGFLQRELGSQLAFDEPCLEPIDSTSQTDGNSDVMASQLLADEMLARELQEQ
LYNEIPESTSVERLSSLGLHLPEEQLGDSLQLASSRRNHQVHHFVGPPPSNRRQASQSHS
LRNRLFRRGTQARLPRSNVPRLRSHIHHQGRRRDRLFPSQMDLDMRMELLEALEAVVSDD
VRMVNQLLDSDREFGENDYEMLLALDENNHTHLGASAAQITNLPESTVNTDNSEVCSICL
ETPAIGDTMRHLPCLHKFHKDCIDPWLRRKRSCPVCKSDI
>Sgl77193 E3_activity/RING/RING 26.2 6.5
MLRSEDSDQAIDLNVEPESSVPCSICLDLVNCGGGRSIAKLKCGHEFHLDCIGSAFNMKG
VMQCPNCREIEKGRWLYASGSSNSSPEPGMDDGSVDNFPFYFTFSEMPYGVQICPFRGFT
QVHPSSQ
>Sgl77205 E3_activity/RING/RING 32.4 8.5
MKFCKTYQEYMQNLESELPGVGLKNLKKILKKCRLDLESHNSSDNDDCPNHCPVCDGTFF
PSLLKEMSAVVGCFNDRAQKLLELHLARGFKKYYVWCKGKQDHISLIQEGQDLVTYAMIN
AIAVRKILKKYDKIHYSKQGQEFKSRAQSMHVEILQSPWLCELMAFHINLREKKANTKRG
ANLFEGCFLKFTDGKPSLTCDLFDSVKVDIDLTCSICLDTVFDPVALTCGHIFCHICACN
AASVTIVDGLRASSPKQKCPLCREAGVYESALPMVELNILLRRRCHEYWEARLQSERTER
IKQAKEHWEFQCRAFMGV
>Sgl77212 E3_adaptor/Cullin_RING/DCX/DWD 54.2 10.6
METAALMEVEEQQQPNSTPTSFNRFPLKNSIQTNFGDDYVFQITSKEDWSSMAVSLSNNL
VKLYSPSTGQYIGEFCGHSSTINEIAFVDPLSPHLLLSCSSDASIRAWDCRNLQQVSMIN
AGPSQEVFSFSYSGVNNLIAGGCKSQIPIWDWRNQKQVACLEESHVEDVTQVRFIPGTEN
KLLSASVDGLMCLFDTSGDINDDDHLYSVMNVGTSIGKFGFFGRNHEKLWCLTHIETLSV
WDWKEEKNVADFQEARKLTSENWVQDHVDYFIDCHCSTEDDRLWVIGGTNAGKIAYFPVN
YNGRIMSSPEAILEGGHAGIVRTIMPASGLRGRSSNRNMFGWTGGEDGRLCCWSSDETSD
VNRAWISSNLTVKPSKSRKKNRHQPY
>Sgl77226 E3_activity/RING/RING 35.5 2.9
MDGQLLSTSSINGVVVTSYAENVSNSNTIYVNRPVDRFFTVELCYQDYRNENPNETNLVF
KLEKECDLCEALETLNVDVTAYYWVIEVVTKSCEVLLEQVIVDGRKCLKMLVKIMIVEQE
EEATDVGVDVSNIVEVKAFLSAKGGVSFISGEQVGSNMGPCSICLDEFDQKPENNNDVND
PKPKDIALLPCSHVLHGDCLVPWIAKGKTTCPLCRFNVLPNECMIKLS
>Sgl77260 E3_adaptor/Cullin_RING/DCX/DWD 37.1 0.4
MATVSAWPNNSNPNSNPNLNPNPSSSPQPPYLTVDPNHQPQTPSSPPSPMSQQSEHLYFD
SNSNSDSQEQDSLTPPALPPIRTSLVENPNPNPSPNPDSPNSIASQPPNLLHVSFNQDYG
CFASGTDRGFRIFNCDPFREIFRRDFDRGGGIGKVEMLYRCNILALVGGGPDPQYPINKV
MIWDDHQSRCIGELSFRSEVRGVRLRRDRIVVVLEQKVFVYNFADLKLLHQIETSPNPKG
LCEVSQSAGKLVLVCPGLRKGQVRVEQYISRKTKFIMAHDSRIACFALTQDGGLLATASS
KGTLVRIFNTFDGTLLQEVRRGADRAEIYSLAFSTTAQWLAVSSDKGTVHVFSLKVNSGT
PVNETTSPPPESNTSGAPAGSSLSFIKGVLPRYFNSEWSVAQFRLIEGNQYFVAFGHQKN
TVVILGMDGSFYRCKFDPAKGGEMIQLEYNNFLKPEEPF
>Sgl77293 E3_activity/RING/RING 14.5 7.1
MAGKKRSMSLDADVYGVQKEWDEALCPICMEHPHNAVLLLCTSHAKGCRSYICDTSYRHS
NCLDRFRKLNTDSRTSPQDNTPVSQNLQDSSLVSDPQLTSLFGNDLPVLHRANSSGNSFT
SSRRSGDSTDNVEQEAVERQNLEQDEFAKKSSLQCPLCRGDVLAWTVVEEARDHLNMKPR
CCTRDSCSFVGNYRELRRHARRDHPKVRPAEVEPSQQRAWSRFEHQREHDDIVSAIRSAM
PGAVVFGDYVVDYNDRTPVERERTSSDASGRLFTTLFLFQMLGSMHSLAGPRSRSRPWTR
HRRLSGGSSRQRYHWGENLLGLQDEGGDGDDSFTDDDEMNILNEAEQGTSSTTRQRRRLN
QSGFRRNRL
>Sgl77295 E3_adaptor/Cullin_RING/DCX/DWD 87.3 10.1
MAVVELETYPTNPRVKPASKKPNKSPESKYWKSFKTTEVKGLVSSITSIDFSPISPHHFA
ATHSASLSFFNPHHPFTPNEPISTTHAFKDISFSASYRSDGKLIAAGSQTGVIHVFEAKT
RNQLRQLKGHSRPVRLVQYPSFDKLHLFSGGDDSVVKFWDVSTETTLSNFIGHKDYVRCG
SSSPIDDNLFVSGSYDHTVRVWDVRSGSNNNNNNSALVINHGKPVEDVMFLPSGGLIATA
GGNVVKIWDVIGGGKCVHSLETHNKTVTSLCVGKVGRISGQESDQYRLMSVSLDGYLKVF
DYAKLKVTFSMRFPAPLLSVGFSPDCSTRVIGTSNGVIYMSKRKKVKVDEERRDGEFLGF
QYREEPRKRVLKPSFFRYFHRGQNEKPSGGEHLILRPKKVKLAEHDKLLKKFRHKDALVA
VLNKKNPDNTVAVIEELVARKKLFRCVSNLDIQELELLMVFLQKYTTLPRHAGLLMPFAS
KVIQMRAEDIQASDSLKSQLRNLKRTIQEELRIQQSLLELQGVISPLMRIAGRR
>Sgl77324 E3_adaptor/Cullin_RING/DCX/DWD 84.8 16.6
MAQSNWEADKMLDVYIHDYLLKRKLHNSAKAFMAEGKVATDPVAIDAPGGFLFEWWSVFW
DIFIARTNEKHSEAAAAYIETQQMKTREQQQQQQQQQQLQMQQLQLMQQRNAQMQRGGPN
HPPLGGPVNGIMDNRMALLKSASNSQGQLIQGNSGSMSAALQQIQARPHMTTDIKSEVNI
SGSQKSLPMDPSSIYGQAILQSKSGLGSAGLNPGINSLPLKGWPLTQGLDNLRMQNQKPL
IQNQILLAAQQQQVLSQAQTQNSFGSSPSYGDNDPRRFGGLPKGSLNTKEAQSARNDVCS
PMQSSSPQMKMGQMQQSSSQQQEQLQQQQLQQNNRKRKQHSSSGPANSTGTGNTVGPSPN
SPPSTHTPGDGIGPANSLQQANSMPKNLIMYGAEGTGALASSSNQLDDIEQFGDVGSLDD
NVESFLHDGGDGKDLYGTLNQSPVEPKAEPSKGFSFAEVDCIHTRNKVTSCHFSSDGKYL
ASVGHDKKAVLWNMDTRKQESTPEDHTLVITDVRFRPNTTHLATASFDGSVRLWDASNPS
YCMNVYPGRGTHVMSLDFHPKKNDLFCFCDSNNEIHYWSMSPFSCIRMSKGGTAQVRFQP
RVGQFLAAASDKVVSIFDVESDRTTQSFQAHSDVVTYICWDASGELLASVSQDSVKVWSL
ASGECIHELSSNGNQFHSCVFHPSFASLLVVGGTRSLELWNMADNRSMTVPAHDNIVSAL
AASVTGMVASAGHDCTVRLWK
>Sgl77325 E3_activity/RING/RING 15.4 14.9
MGNTPTIETQNQQEEDNEETIFDSFICCVCLDLLHKPIVLECGHVSCFWCVHKSMDAVNV
SHCPICRHPYHYFPTICEMLHFLLIKLYPLAYKKREAQIYKEEKANRCFSPQLDSKDLYI
SDDSKPSPAVNMSSDMASVSCITSNGSSTGEGNYSSATNIQRAFERVSTSDVLCPSCKQL
LFRPAVLNCGHVYCEACIVIPEDGIIICKVCEYPHPSDCPNVCLAINNFLEERFPKEYAA
RRENDERKRERFYHKSPSSCSGSKKSAKNICCIPPRHGEEFKPGSKEHCPKIHPGAGCDY
CGMYPIVGDRYRCLNCMEKMGFDLCGACYNTRSKRPGRFNQQHTSEHRFELIQPRDASSN
MMLRIVGGYLVNSSGEPVLAIGAIEDPHDGWVAVESLDENLDELDNSEANDGSVDIEFSD
AVEDSGDHDHNGRENPPF
>Sgl77344 E3_activity/RING/RING 13.8 13.8
MESDGGGVATAVTPRRLSNQHSTLRDTFIASDLADAINREFTINCTIDNSNTTSSRRESS
LTLGAVLNNEKKSPPPPNIVVRTLLEIIHNDETLSPRGSGGSPTGRRTWKSFKERLRLKK
HQNQSRNRNSNSQRWESSFPVPRSDVIPSSRSLSVGEMMANRNSLRSNSQRRIDTVPADD
LTLREVDSGGSPRSGGSFRLSAALAAEREQTRRRLSRELDEGNRLGEDGEESDGSPLGND
DDNQDENTDEDEGGIPDLGPPANQPMRMSLMDLLEETDRQAGISGPTYRLDDEEEEEEEE
EVEQEVEAEDAGKGEYSCCVCMVRHKGAAFIPCGHTFCRLCSRELFVQRGNCPLCNNFIL
EILDIF
>Sgl77351 ULD/UBL/SUMO 101.3 0.2
MTAENDAGNTASMEDKKPADQSTHINLKVKGQEGNEVFFRTKRTTALKKLMSAYCDRQSV
SMESIAFLFDGRRLRENQTPEELEMEDGDEIDAMLHQTGGYY
>Sgl77363 UBD/Alpha-Helix/UBA 29 0.0
MAAPEVDKRLLEELQEMGFSLGCATRALHYSGNTSLEDAIDWIVNHENDSDIDQIPLIPV
DIVLDAPKPFPISEGVKISAQRLSLRNESKQSRKEKESELEREREKERIQAWKRILEAKQ
IAEENARKRMIMLREADKEEERKARKIIRQKFEADKAERRAKLGMPSAPSLSTQPACHVD
NMVQEQSAEVSKPVKSTKKAELLSDCLRGLRRYHKDEDARVKKAFLTLQIYIRNVMNNPD
VEKYRNIRFSNPVFQERVGSLTGGIRFLELCGFERTNQAQFLRLPREKLDMETLTSAMSA
LQSAITNPFFGLLSAEQP
>Sgl77444 E3_activity/RING/U-box 106.4 0.3
MAKTGVVSEGDSIRVLELKKELRLLMKAITDEEDNQIHTNNHHNNNDFVSNSSSSSFFDT
IDKAKDLLSALQDVKLKRTTSLRLDDGTLSCPPEFLCPLSKQLMKDPVIISTGQTYDRDF
IQKWLKAGHRVCPITQQVLSHSLLTPNYLVRKMISQWCETRGIQIPDQVGYINEEGASEN
DRDYFSSLIDKMSKSIGEQKAAAKELRLLTKRMPSYRALFGESTEAIPRLLRPLTQRRGS
FSSRSNDSISNECHPDLLEDLITTLLNISIHDSNKKLVAETPMVITLLIDALRCGTPESR
SNAAAALFTLSAVDSNKVLIGKAGALKPLIDLLEEGHAMAVKDAASAIFNLCIIQENKAR
AVREGAVRVVLKKIKNGVHVDELLAILAMLSTHQRAVEDLSELGAVPSLLTIMRESSCAR
NKENCVAILYTLCINDRSKLREVQEEERAYGTLSQLAQDGTSRAKRKASGILDRLHRAYN
LTHTA
>Sgl77447 E3_activity/RING/U-box 89.8 0.0
MSPMAAMSSVAKQAEQLRQDGNNYFKKDRFGAAIDAYTEAITLCPNVPVYLTNRALCYRK
KNNWARVEEDCRKAIQLDNSSVKAHYMLGLALLQKQEYSEGVKELDKALDLGRGANPKGY
MVEEIWQELSKAKYLLWEHESSQRSWELQTLKGPKEKHLMDSSKTKEFIDEAADDHVKQQ
LKALKLIFGKAAEPDSPTEVPDYLCCRITLDIFRDPVITPSGVTYERAVILEHLEKVGKF
DPITREPLELSQLIPNLALKEAVQAYLNTHGWAYRMD
>Sgl77474 ULD/UDP/UBQ/UBQ_PIM 138.8 6.0
MLIFVKTLQGKTITLEVESTDTIEGVKSKIQEKVIDENVQRLMFAGRQLEDGKTLEYYNI
QKESTIHVVLRLPLRCGRIIKVKTPNGKEIEIKFEPTDTIDRIKERIEEKDGIPPAHQML
IYAGKQLADEYDKTAKDYGIEAGSVLHLIVNRRVIKPLSPPPVKRSVVSKKRSASASSGK
PIKRTFSRVNSSSETQEPNSVSTMATGSKKTIISVPSAADLLKHAQAKRSPSGSTPFSQP
APKAVATPSNQLQINLPASFCDFSGTSSMVSELGQLHFPAARNYLEDFTTASILNDSVAY
CIQSLQGILTAKERLLALEAKVEALTNSEKALKERIRSDGAVMADLKKKNKELSDDAKKM
MKSEIYDVAGYYVYRTKSELMKEFLDGNTSHWTPEEDIKHFNDYFSNVIPPGVDDGTDMD
>Sgl77501 E3_adaptor/Cullin_RING/DCX/DWD 90.9 19.1
MASEIDNTSSFGSTSSSSSSIISNNSTTTNYLLSDFININTQQINPSFSVPHPYYNCIAT
LKTPNHHHITCLAIHNNLLYAATGNQITTFDLTTLSPIPSFDAQDLSSGGFIKSIVFVDD
HKILTAHQDSKIRAWKDQQPQGPQHRLITALPTMKDKLRRFIRRSNYVKVRRNKTKLWIE
HNDAVSGLAVNVNDGVSVIYSVSWDKTLKVWRGSDFKCLESITAHEDAVNAVTVSGDGTV
YTGSADGTIKVWKNKNDNNNSNNDKVWRHSMVSTMEKHRSTVNALALSSDGKVLLSGGCD
GMIIAWEKDDDDDDRMVENGVVGGHDGAVLALIRLDDDHDLFVSGGADRTVRIWGRVGKG
YGGGGGGEKRGLLFCCMGVLEGHDKPVRSLVVVPPRSEGGSDGVVRVCSGSLDGEIRVWE
IMVSELIINHRPSCNKDY
>Sgl77506 E3_adaptor/Cullin_RING/DCX/DWD 110.3 26.8
MSIKMSNEEVSILAIKQALKALRKRHLAEEGAHTAAIAAISRPLIYQGSEWKEKAEKLEL
ELQQCYKAQSRLSEQLVVEVAEGRSAKALIQEKETAVDNLEKEVAQLSDECSELKKLLDE
KTKGFELLTSENEELKKQLEETSVKAKNAEAENKMLVDRWMLQKMQDAERINEANALYEH
MVDQLKSSSLQQIALQQVDGVVRQSEEGAEFFVESSIPTTCKNRFHAHDGGCASILFEFN
SDKLVTGGQDRSIKIWDTSTGALTRTLYGSLGSVLDLATTHDNKTIIAASSTNNLYVWDV
NSGRIQHTLTGHTDKVCAVDVSKISNRHVVSSAYDRTIKVWDLQKGYCTNTIIFPSNCNA
ICFSTDGRTICSGHVDGNLRLWDIQTGKLLSEVAAHSLAVTSISLSRNGNTILTSGRDNV
HNLFDMRTLEVYGTLRGSGNRVASNWSRSCISADDSYVAAGSADGSVHIWSIQKGDVVST
LKEHESPVLCCAWSGLGKPLATSDKNGVVCTWM
>Sgl77509 E3_adaptor/Cullin_RING/BCR/BTB 23.8 0.0
MSPMETSDKLTGKPITTGNLPEYDVNVITSGGLRIPSHSHILAMASPVLEKFVEKPKRNR
KTGEKAIPILGVPCDAVSTFIRFLYSYRCTDEEMEKYGIHLLALSHVFSVPQLKQRCTKG
LAESLMVDNVIDVLQLARLCDAPDLYLKGMKLTASKFKSVEKTEAWKFVQKYDPWLELEI
LQFIEETELRKRRTKKHKEEQNLYIQLSEAMDCLVHICTEGCTIVGPYDMEPSKKKEPCR
RFSTCHGLQLLIKHFATCKKRVNGGCSRCKRMWQLLKLHASMCEQPGHCRVPLCRQFKLK
MQHEKKLDDAKWRLLVRKVVSAKTISSLSLSKPQRNTEMSKHFHASNLKGGCIQCP
>Sgl77528 E3_activity/RING/RING 16.5 17.0
MVGYQLVSSSTSHESLKVIEADIQHANMLAASIPRNKSGNWLQMKLVHNDLAPLIFYLLQ
WFDCSCTCLLPSCLNLFYVVIYKVNADGRPDMMSYGRRATLKEFYAIILPYLHRLHGSMS
ELNDGANSSNSSDLAIRKIAQESRQLSDIDFDREDECGICLEPCTKVVLPNCCHSMCINC
YRDWNLRSESCPFCRGNIKRVQSGDLWVLTCGTDVVDPKTVLKEDVLRLYLYINSLPKDV
PDALFLMYSEYLI
>Sgl77542 E3_activity/RING/RING 19 10.8
MPFLRHKNTTNSPTSPPPPPPQSMSVTGPARPIRFVYKDENGKLGIDPQALAVLQLVKQP
IGVVAVCGRARQGKSFILNQLLGRSSGFQVASTHRPCTKGLWLWSTPLKRIALDGTEYNL
ILLDSEGIDAYDQTGTYSTQIFALAVLLSSLFIYNQMGGIDEAALDRLSLVTEMTKHIRI
RASAGRTNASELGQFSPIFVWLLRDFYLDLAEDSHKITPRDYLELALRPVQGSGKDITAK
NEIRESIRALFPDRECFTLVRPLNNETELQHLDQTPLHKFRPEFRSGLDALTRFVFERTR
PKQIGATIMNGPMLAGITQSFLDALNDGAVPTILSSWQNVEETECRRAYNRAAEVYNSSF
DKSKPPEEAALREAHEEAVQNALSIFNSNAVGAGSARLKYEMLLQNSFKKEFEEYKKSAY
MEADSQCSDAIQKIEKQLRTACHAPDANLMQILKVLDNLLSEYEASCHGPGKERKKAIFL
QKCLEGPISDVAKKQLDEIGLERNALEFKCQSLDDKIALLTKKLEASEKLKSEYFKRYED
VTSDNRKVAEDYLNQVTNLQSKYGSVDERCSNLLKTLDSAKKECSEWKRKYEEVLLKQKA
EEDEASAEVAALKSRGSAAEASLAAVREQAQSAKEEADEWRRKYEIAAREAKLALGKAAS
VQECTNKNLQSREDMLRAEFDKALTDKDKELKDKVTAYSFAPAYRLQVTKMGQDPMHPLM
VKEGSIRVNIRPNHVQTVCNKPEEVLNNLRNSREDEANFSINNDDDNDNDTILTLTLACG
ICNNTSFVNPVVTKCKHYFCERCALKHNSKTKRCFVCNLPTQGIFNVARDILKKMAADRP
GATLT
>Sgl77610 UBD/UBC-like/UBD_UBC 247 0.0
MASKRILKELKDLQKDPPTSCSAGPVGEDMFHWQATIMGPAESPYAGGVFLVSIHFPPDY
PFKPPKVAFKTKVFHPNINSNGSICLDILKEQWSPALTISKVLLSICSLLTDPNPDDPLV
PEIAHMYKTDRPKYESTARSWTQKYAMG
>Sgl77619 E3_adaptor/Cullin_RING/SCF/F-box 12.8 0.1
MEFETDDTTFCKLSDDVVLKIFTLLEDDPRSWASLSCVCTKFNSLISSICCKSKCVASLS
SDLLSLSSSHGFPWSSLFKLSVCCPGLLHCGVLLDNSDFGLHREIGSHDTDSDLSLLSNS
SSSSSSQAHNHQHRYDDRNDADDNSGSGNGESVDDDNDNKLFEGWSMYDDLYFDTMYDNS
ETSAAPVVVTTWADNLDTGFNHDFKRRKIDVTDEDEEDDHNVNNNVNDSSNDIDDRRRQQ
RSHLATGAWNLSREQGMKLLASRFRDDCLYISEWPGCVHGSEEEEEDHNNKRKYMLFRGV
FSDFKKTRVWRTIKDGNHRSKIELNCAFCSCKETWDLHSAFCLKRGFGFHDDGEPVVRAY
VCENGHVSGAWTDLPLYT
>Sgl77638 E3_activity/RING/RING 17.3 10.8
MAESQAQAHFLNPWVLNLEKLGLELKCSLCLKVYNKPTLLPCDHIFCSYCIPKSNLFGSE
CPLCKISIAEKDLRQAPFIANIVNIYKCLDASFSTHMLSSDFSRGSVQCPYPNQRAKNRI
DSSTPGNSNSGTCENVQHEAVDVDMNQMESPESPPSSGVSKGDTTGKCLSKKSAKRTCDD
FGAEGFGKSHDLCSKKQKQISQGVPEMNNTPSNSTDQHAAELDPASLCNFLCVFCQTWKV
TEGSGPMQHFVNGRQVFGSEASHSYVAHVHQSCIEWAPQIYYENDTTMKNLDKELARASK
LKCTTCGLKGAALGCFAKSCRRTYHVPCAYEIPECRWDMTEFLMLCPAHASQKFPSERSK
KAYVKKCSAVQIYNEQQSVSDFDFWATSLTGAKNWVLCGSALSADEKYKLVKFANLCGAT
VAKTWNPTVTHVIAATDTNGACSRTMKVLMAILNGRWILKTDWIEACMLVNSPVDEEPYE
ISLDNHGCSGAPKTGRLRVLNNEPKLFSSLKFFFTGDFVAAYKQDLQNLIIAAGGTILES
KVQLQQSSNELCHPSTTIIVYNDDSTGETNDNLLRQYTAERQALETGSQVIAHTWILDSI
ASGVLKPFAQRFAPKIPVDV
>Sgl77645 E3_adaptor/Cullin_RING/DCX/DWD 64.3 10.3
METVTRRVAQRQNRVSSFTWHRQPSNGSSPSSKDKVCSFWLAGNCRRKQCRYLHPEVTAP
IKRVYKLNRSSFKRSQESEKPLSANCKRENVNCISEYKRNQKISSKNEEGSDPAKIRKYD
HLCQASNATSGDGRNTPRTKICQHWIKDSCVHGDQCKDLHSWCYGDGISLVAQLEGHKKA
VTGITLPSNSDKLFSGSKDGTVRAWNCHTGKCIGVADVGVPVECLISDGPCVFAGVTDAI
KVWNIQLNTEFTLSGPAGQVYAMVAIDGLLFAGVHDGSILVWKFNSGATSFEAVAPLKGH
TDAVVSLIYGAKRLYSGSMDKTIKVWDVETMRCIHTLAKHSEVVMSVLCW
>Sgl77646 E3_adaptor/Cullin_RING/SCF/F-box 19.3 0.0
MAGNERRRMESLSEAIRDDNTCVDKQHTQFLPSWSDLPPELLELILSHLTLRENIRFSAV
CKSWNSVAVSVRPLPLHEPLWLSFNWAIW
>Sgl77785 E3_activity/RING/RING 20.5 10.7
MAESQAQAHFLNPWVLNLEKLGLELKCSLCLKVYNKPTLLPCDHIFCSSCIPKSNLFGSE
CPLCKISIAEKDLRQAPFIANIVNIYKCLDASFSTHMLSSDFSRGSVQCPYPNQRAKNRI
DSSTPGNSISGTCENVQHEAVDVDMNQMESPESPPSSGVSKGDTTGKCLSKKSAKRTCDD
FGAEGFGKSHDLCSKKQKQISQGVPEMNNTPSNSTDQHAAELDPASLCNFLCVFCQTWKV
TEVSL
>Sgl77852 ULD/UDP/UBQ/UBQ_Other 36.9 0.1
MVGYSPAAHEPLLENVFVRKAFSVDHLLTLLDMSKEIITEKINSPRPVRLLLVDSVTNFF
SRASFFDKAGLKERRKEMQKIASKMKHLASQFNIAVVVTNEIRDVVSGQSSTQASPPLPQ
LVSSGRLVKPALGYDWSELVDSRVFLTKIVDIQGVRSRFAVKVSNPRKNQPENNSVASLA
LQKYATEKEVKVDDLTLQLRRRFVHPDSTPAENNMQHGDILTVMHKTGQLLSWDLLSDSR
DYRLCTLQDLCTETFVTDMRVHLDDPVKVVRKQWEEITGVSWKNIMVYYDGKLIRAKTTF
RDIGLKDGDAIFMVGKTVFTKIGTV
>Sgl77890 E3_adaptor/Cullin_RING/DCX/DWD 43.2 1.8
MEDEAEIYDGIRAQFPATFGKKSKPQTSLESLHNTTLRTTTTTTTQKQQFNPSSSSSDSF
PSLSSSSKSWIDSVRPNPKSKLHESDGPPVVAEEDDGPSIGPPRPPAGFTVDDDDNDNEM
IGPPRPIPEEDEDEEEEEEEESRFRIPLSNEIVLKGHTKVVSALAVDHTGSRVLSGSYDY
SVRMYDFQGMKRDLGSFRQLEPFDGHQVRALSWSPTAGFFLCVTGCAQAKIYDRDGLTIG
EFVKGDMYIRDLKNTKGHITGLTCGEWHPNKKETILTSSEDGSLRIWDVNDFKSQKQV
>Sgl77947 E3_adaptor/Cullin_RING/DCX/DWD 73.1 13.1
MEDEAEIYDGIRAQFPATFGKKSKPQTSLESLHNTTLRTTTTTTTTQKQQFNPSSSSSDS
FPSLSSSSKSWIDSVRPNPKSKLYESDGPPVVAEEDDGPSIGPPRPPAGFTVDDDDNDNE
MIGPPRPIPEEDEDEEEEEEEESRFRIPLSNEIVLKGHTKVVSALAVDHTGSRVLSGSYD
YSVRMYDFQGMKRDLGSFRQLEPFDGHQVRALSWSPTAGFFLCVTGCAQAKIYDRDGLTI
GEFVKGDMYIRDLKNTKGHITGLTCGEWHPNKKETILTSSEDGSLRIWDVNDFKSQKQVI
KPKLAKPGRVPVTTCAWERDGKSIAGGIGDGSIQIWNLKPGWGSRPDIHVEQAHSDDITG
LKFSCDGRHLLSRSFDCTLKVWDLRQMKRSLKVFDELPNHYAQTNVSFSPDEQLILTGTS
VERDSPTGGLLCFYDREKLELVSKVGISPTCSVVQCAWHPRLNQVFATAGNKSQGGTHVL
YDPTMSERGALVCVARAPRMKSVDDFEVQPVIHNPHALPLFRDQPSRKRQREKILKDPIK
SHKPELPMSGPGHGGRTGTSSGSLLTQYLLKQGGMLKETWMDEDPREAILKYADAAEKDP
KFIAPAYAETQPKPVFEDSDKEDEE
>Sgl77993 DUB/USP 225.8 4.0
MKKLDLPVFDGDNPDGWILRAERFFHFYRLGEEDKLEAAIVALDGDALLLFQWEHRRRPI
TKWEDLKRLLLHQFRSTASGTLQEQWLDHKQTSGVLEYRRRFIELVAPLEGIPESLAKSH
YINGLKGDIRAEVRLLSPTTLDSAMDLSIKVEEKLKSKTQSFGPKHEPKPSSSLNSWKTN
HISPNPNFTKNPQGPNTFSSPQNRYNPNRNQPNKPTGEIRRLTEKEIQQKREKGLCFRCD
DKWSLNHRCHVAGFCALCAMQKHVNCALKSTGRSLAPKDLVSNLRRISRTFRNARQEDAH
EYMIHLLESMHKCCLPSGVPAESAGAYDKSLVHKIFGGRLRSQVKCLQCSHCSNTFDPFL
DLSLEILKADSVHKALMNFTAAEQLDGGERQYKCEKCKQKVRALKQLTVSKAPYVLTIHL
KRFRHFSGQKIDKKVSFGSTLNLKQFVSGAYDGDLTYTLYGVLVHAGWSTHSGHYYCFVR
TSSGIWYSLDDNRVYEVSEKKVMDQKAYMLFYVQDRKNVGTKKAMDAAHKENLFSTMRNA
SSPCSIPGVKSFQNGYFDKKAQEVIPSNQVTKQSEGHNASERLVEQKNSKCVPTNAIAMD
NELNQKTSSTKENPPITNTILNGMVNAATKLGDDNQSEKSAKATASSCPDNNREKDVASI
EKPSVSNCSFSVAIVPHSNDSQMAGTPTNIRNSLSNDSKPIIPSDSVIQPTTTFSTIKDG
ASEPVSDNCSVLSKPSVKRSRGSSLAKSSESTPHQRLMKDFLKSRVGGYLSTKMLYGASL
TLRKNKKFKRMKKRLKSVMQEKLLTEKSDPADMGPSTSGSDPLGNFKHSLKEGHNTCDSV
GENLGPRKDFNDSWSKEPNPHLVNGDSVATRGLKDSAGDILGANYKDFKNSCSKEPNSQL
VNGNSATTGGLKESAVGRWDGIEPPVKNVEPNGGRDTLTIGHVLDEWDEEYDRGKRKKVR
VSRNSFGGPNVFQEVALKKAKLKVKKA
>Sgl78004 E3_adaptor/Cullin_RING/DCX/DWD 23 0.0
MAEVQKSEEATISFKNLFNREYHGHKKKVHSVAWNCTGTKLASGSVDQTARVWQIEPHSH
GSGSNLRKMQGTGAATDLASKVQCTSETATTALKPKEEVDDSLHVDMKVRCPCGSSLLTE
TMIQCEDPRCQVWQHISCVIIPEKPMDGIPPTPPSQFYCEVCRLNRADPFWSTLGHPLFP
VKLIPNNAPTDGTNPVQIVEKTFHLSRTDRDLLSKPEYAVQAWCMLLNDKVCFRMQWPQY
ADLQINGFPVRALSRPGSQLLGANGRDDGPNISQCTREGINKIFLSGCDARIFCLGVRLV
KRRPLQQILSMIPKELDGEIFEDALARVRRCIGGGEAENADSDSDLEVVTESITVNLRCP
MSGSRMKTAGRFRPCAHMGCFDLETFVEMQQRSRKWQCPICLKNYSLESIIIDPYFNRIA
NMMQSCGEDTTEIEVKPDGFWRVKGENECKDLRQWHLPDGSICLPDEGELKHKPEASKPV
KPEGTGLKLGIRKNSNGLWEVSKHGDMNTFSSSDRIPENLENGGLKVIPMSSSATISGRD
GEDPSVNQDATVNFDLSVTNGVELDSISLNLDPTFGLTTQNALATAKDANVIVLSDSDSE
NGMMVHGIVHNNGLMDNGVNYTVNSHGITGSYQTDAGLGVGGSSCLDLFHPADDEFGLPI
WPGMPSTTQGASSFQLFGSDGDGSDTLGNPHLSAVNCSTSMNGYMLAPETAMNPAAFVPD
SAVNHPSHDLNDGLVDNPLAFGGEDPSLQIFLPTRPSDTCGSSDVRNHQDMANGLSNEDW
ISLRLGDGGGRNPGDSGAVNGLHIGQQPHSRDGNMDSLAETGCNNKRNVEADDIIPDSPS
SSSSSVTKSLCNSSIRSTQDAIQDDPACNAIEPTKVKKHKKKIINDGVRAVVCDGEQPPA
CAFGKAGKTNESIVEDDSTRSAQDTLPVPEDPACDIKEAIKAKGKKKKVVEDEVRTPQAG
QVVVVCALRSRYTNPIEQLGCALVSTGQGSPDRYILQSRKSNRLMHEEDEHDHVRSTPQG
SPDQYVLQSRKSKRLKHDDDEEEEDDDDDCFRSTRHGSLEYHVLQSRMGKKLNEQKKQDD
DDDHIRSTNQDSLQNLVPDSKEVKKLKKKLKKQNQAEDDDDRSAQPGLPEDSAVDTREAK
KARKQKKKDANEEASADRQQPPPASSSGKTGKIKKHFVQDDSIRSAQDAFQEDPAYDTIE
PTKAKKRKKTIIKDGARAAVNDVHQPPGCGKTKEYVVEDDRNRSAQDTLQEDPGYDTIEP
TKAKKHMKTIIKDGVRGAVNDGQKPHAHASDFGKAGKTKEHFVEDDSIRSTQDAIQDDPA
CNAIEPTKVKKHKKKIIKDGVRAAVSDGEQPPACAFGKAGKTNEPIVEDDSTRSAQDTLP
VPEDPACDIKEAIKAKGKKKKVVEDEVRTPQAGQVVVVCALRSQGKH
>Sgl78017 E3_adaptor/Cullin_RING/DCX/DWD 128 12.6
MNEGREAVKTPLEARRSSMTTKRAYKLQEFVAHTSTVNCLKIGRKSSRVLVTGGEDHKVN
LWAIGKPNAILSLSGHSSGIDSVGFDSSEVLVAAGAASGTIKLWDLEEAKIVRTLTGHRS
NCISVDFHPFGEFFASGSLDTNLKIWDIRRKGCIHTYKGHTRGVNAIRFTPDGRWVVSGG
EDNTVKLWDLTAGKLLHEFKSHEGQVQCIDFHPHEFLLATGSSDKTVKFYDLETFELIGS
AGPETSGVRCMAFNPDGRTLLCGLHESLKVFSWEPIRCHDTVDVGWSRLSDLNVHEGKLL
GCSYNQSCVGVWVVDIARIEPYSVRARSNGHSELKSVSSGNLSVQNDNTSKVGSGRLSTL
QNSDMAEKETKPSGRFLVPANANQGNKDSRISPNPGGIPGTPHRVSQSTSPRNTLAPTTI
VQKRNSSKTHLVTIASTNSKPDVMPIIVPRDDVRPEQTEFKREVFSRRTITHHSQSKPAE
LRRFSNASEESDGPTINPQPEITTVKAPETSGVENKSVLPAVRNLNIHFPVVERNPKEDR
CVGSLKAENNSSLQPLGSSPLDNYEVRVPRTSKVSASSENQRPGKTRSLVANWEKREKSP
SSEGPTTSNSSVSVNVDSRPMNMNTKPRGYSLSAEKDMPSMTDDDIIVQIIGRHDQFLGS
MQSRLGKLQAVHRFWDRNDVKGAIGAMEKMADHSVIADVVSLMIEKTDIVTLDICVCLLP
LLANLLESDMDRYLGISLDMLVKLVRVFGAVIYSAVSASSSVGVDIEAEQRLERCNLCYI
ELERVKRCLPALMRRGGSVAKSAQELNLAISAACE
>Sgl78035 E3_activity/RING/RING 18.6 6.6
MNGGSTIAVAVAFDLNSEFLIPNSSVTTTITPLQTPTTRRCWFFVLHACTNEPIRCLMPV
TISAELVKPTSSSSYFNFPMDQGNPSSAFTDEDVVDISSDDEDKEAHIVPPPPGHMSASA
SKRRLPNWVDSDEGFHMQPGPSSRRGTHPNIVRRFQGESTPSTSYGTNNGTTLGNGSSFP
SRKYDENSYWNNSSHAHAEHQQHRNKRLLPPSIQASGSNAKQRNSWDNLGNNRGYFTKGS
DGDAYMYDNNHPRILPHTLVRGKPGSSGDYNTTSDLYQTTGVGEENISGEERIIFQAALQ
DLNQPKAELDIPQGLLTVSLLRHQKIALAWMVEKETRTLHCLGGILADDQGLGKTISTIA
LILKQWPAQMKSKSEKHDNNFAEALNLDDDDDDNPGNKEEDPNAGKCKSAEVINIEPELY
NLDDDDDDDDGSGSMETVKKVENDDGLKSNSGSSSSHPKVQGKRPPAGTLIVCPATVLRQ
WARELGEKVAKKANLSILSYHGGSRTKDPKTLAKYDVVLTTYAIVSNEVPKQPIVDEDDG
EEKPGDRYGLSSDFSGSKKRKHASTNKKGKKGKKKADSSLFSQAGPLARVNWFRVVLDEA
QTIKNHRTLAARACCGLRAKRRWCLSGTPIQNSVDEMYSYFKFLRHDLYSSYKKFGEKIK
NLISRDPNMGYKKLQAVLRTLLLRRTKETLLDGEPIICLPPKTIEMKSANFTVEERSFYA
QLEAESRSQFKAYAAAGTVNQNYANILLMILRLRQACDHPLLVKGFSSGSARKTNLENAR
KLPRHLLTELLNHLDAASAICQICSDPAEDAVVTICGHVYCHQCVAYYLNGFDNVCPARR
CKEQLNDDVLYSEATLKCCLYGDDVDGKSVNDDGCSNNPSILSTEYSSSKIKAALEILLA
HYELNSKYIENDEFGGTSAGNSISAQVRIEKMENSSSQGPIKTIVFSQWTRMLDLFEYSL
NLYCIPYRRLDGSMSLAARDRAVREFNTIPEVTCMLMSLKAGNLGLNMVAACHVILLDLW
WNPTTEDQAIDRAHRIGQTRPVTVSRITIKDTVEDRILALQEEKRKMVASAFGEDHVAGP
GARLTADDLRYIFLGSRGI
>Sgl78061 E3_activity/RING/RING 29.6 8.0
MSSAGVAIAIPQSYFCYQCNRTVTLIPPPNSDLSCPNCSGGFLEETPQNPNPNPIPHPHP
FASSSPFYPDPLSLFADPSFSPSLNSRSRGPFVLSSTSIDLENPRNFSPFPPPNAEGFRP
FDFLQNYIVNLRQRGANVQFVVENHGDDPNFRLPTNFGDYFLGPGLEQLIQQLAENDPNR
YGTPPASKQAIDGLPNVVITAEVVNSDSNSCAVCMNEFEVGLNAKQMPCKHLYHSDCLIP
WLQLHNSCPVCRYELPTGDPDYDNQRANNRQGGGSSEEGTGNGGAQVEGGGSESGNGSGN
ERRFRISLPWPFRGFGGNNDGNNSGPSAGGQQGGGSGGQGSEPRQESLD
>Sgl78065 E3_activity/RING/RING 37.6 5.0
MDENSKVIDGGAAKTPADNSATLNPNPNPNPNPNSDVTITNSDVDGGSDGGGGGGGGTLP
QQNQSSRTPFTNLSQVDADLALARTLQEQERAYMMLSMNGGGGVGFGRWETGIYIPDDDD
DDFGDSHEYDDEDEDVDEDDEDNEEFIDNYDDDDEDAFDIHAHDDSGDDDDATNVELDPS
AYPDDEAYARALQDAEEREMAARLLAMAGISEREIVDLDEDHGGHSQDTWEEVDPDELSY
EELIALGDVVGTESRGLSADAIASLPSTNYKSKNNNETETDSCVICRLDYEDGDAMITLP
CKHIYHSDCINNWLKINKACPVCSTEVSTSGNSK
>Sgl78068 E3_adaptor/Cullin_RING/SCF/F-box 18.6 0.0
MEIMNNKKLKKEEEASKKDRISELPDSILLHILSYLPAKDALLKASFLSKRWTPLRPFLP
SLVFVQPTRPPTSSGVDFDRNWASFVDSTLIRIDFRHLTRFCVAFRYTLYLLLAILLYCI
RFDSMCASKYRIELIQI
>Sgl78101 E3_activity/RING/RING 12.1 13.6
MDSNSIFLEDFGQKVDLTRRIREVLVNYPEGTTVLKELIQNADDAGATKVCLCLDRRSHG
VDSLLSNSLAQWQGPSLMAYNDAVFTEEDFVSISRIGGSNKHAQAWKTGRFGVGFNSVYH
LTDLPSFVSGKYVVLFDPQGVYLPNVSAANPGKRIEYVSSSAISQYKDQFFSYCAFGCDM
RNPFNGTLFRFPLRNADQAAESKLSRQAYSEDDISSMFTQLYEEGVFSLLFLKSVLSIEM
YVWDVGDTEPRKIYSCSVSSVNEDIISHRQLLLRLSKLSSISTFEMDSFMLDFVSEAING
SSIQKRTDTFYIVQAMASASSRIGSFAAKASREYDIHLLPWASVAACLSDDSTNGDALKI
GQAFCFLPLPVRTGLTVQVNGYFEVSSNRRGIWYGEDMDRSGKIRSIWNRLLLEDVVAPM
FRNLLLGAQGILGPTKSYYSLWPAGDFEEPWSILIQHVYKNVVQAPVLYTDAGGGKWVSP
AECFLHDEEFTDKEELADVLLQLGKHIVRLPNSLRYMLLKSITDFEQKVITPDAVRCFIR
ECGSLSSLGSAQRLLLLEYCLEDLLDSDVGRYAKNLPLLPLANGGYGSFSEASDGSSFFV
CNELEQKLLHQIPDRVIDGNIPNKIMKRLLAVADCSGANLIVFKPECLVQLLDKFLPPVW
KFKSKVFWEHGPGQNNHPTQSWFVLFWQYLSHQCENLSLFHEWPILPSTSQHLYRLSKQS
KLINVENLPERLKCVLVKVGCKILDTQYGVEHPDLSYYICNATGSAVMESIFDVISSSGG
VLQNCFHVLEAEERNELRNFLLDPKWYIGGHMSDSDTWKCKKLPIYRVYGEESDNLQFSD
LVDPQKFLPPKGVLKFFLGTEFILTSSDIEENILQRYYGLQRMGKAHFYRRQVFGMIKDL
PAEDRDSVMLSVLRDLPHLCIEDSSFKEVMKNIEFVPTHTGAIKYPGSLYDPRNEELLAL
LEDTDLFPCGVFHESEILDILQGLGLRTSASLDTVIQCARYVERIKEKDPEKAYMKAKVL
LPYLEANAHRWAAIPLNDEQGALNRVFSRAAVAFRPRNPKSDLEKFWNDLRMICWCPVIV
SAPYQALPWPSMSSVVAPPKLVRPKTDLWLVSASMRILDGECASTVLSYQLGWSSPPGGN
VVAAQILELGKNNETVTDQAFRQQLALAMPRIYARLTDIIGSDEMDIIKAVLEGCRWIWV
GDGFATVEEVVLNGPIHLAPYIRVIPIDLAVFKELFLELGVREFLNFSDFANILCRMASR
KGDEPLTAEELTAAILVVQHLAESPFPEKHVKIYLPDASAQLLPASDLVYNDAPWLLGLE
DSDSISSHASNILLSARRSVQRFVHGNISNDVAEKLGVCSLRRSLLAESADSMNLSLSGA
AEAFGQHEALTTRLKHILEMYADGPGILFELVQNAEDAGASEVTFLLDKTQHGTSSLLSP
EMADWQGPALYCYNDSIFSPQDLYAISRIGQDSKLEKPFAIGRFGLGFNCVYHFTDIPSF
VSGENLVMFDPHACNLPGISPSHPGLRIKFAGKRILEQFPDQFTPFLHFGCDLQNQFPGT
IFRFPLRTASTAPRSQIKQEGYAPEDVLSLFSSFSKVVSETLLFLRRVKSISLFVKDGSD
TEMQLVHRVQRHTVLEPERPPHALQYMFDYLDGIQLCKVDKNQFFEKLSRYGGEDLPRRL
QKVIVREQTSLDTTSHAWMMSECLGRGQDKSVDAKSRSHKGLPWAAVAAYLHSTKVDGDS
CVSALSEGSLATISSTSQDVELNTKCLKNFEGRAFCFLPLPISTGLPAHVNAYFELSSNR
RDIWFGNDMSGGGRKRSDWNIYLLEHVAAPAYAHLLETLATEVGSCEGFLSFWPTKLGGE
PWSSVVRKLYMYIADFEIRVLHTKAKGGQWISAKQALFPDFTFEKMPQLVDALSDVGLPV
VIVSQTLVELFVEVRPSLHFLTPQLLRMLIRRKCKFTERSALILTLQYCLFDLEKPVQCN
CLYGLPLIPLANGLSTTFNPRGVDERIYIAHGNEYDLLKDAIPTQLIDREIPEDVYMKLY
DIAQNEESNVSFLTCHLLEKLFLRILPAEWRNAKQVKWIPGHAQQPSVEWMRFLWNYLSS
SCDDLSVFSKWPILPVGKDNLMQLVENSNIIEDEGWSENITSLLLKVGCLFLRSDFPIEH
PQLKHYVQSPTAAGILNAFLAIAGTIENVDELFADSSEGELHELRNFILQSKWFSEINML
GKNIEVIKCIHMFESCRSRKLVSLNKDIKWLKPSGVREDLLDDDFVRAESEREKMILSTY
LDVQELSKAEFYKQYVLNRMSDFLSSQGALSAVLHEVKLLVDEDASVKDAISNAPFVLTC
NGSWRQPSRLYDPRVPELRLLLHTEEFFPAKEFSDPGTLDMLSCLGLKQSLGYTGMLDCA
RTVSLLNASKDLETIAHGKRLLACLDALGAKLSIEEGEESSKVFGEGPVSLHVKDDCDID
SVLGNLNDAQPQEEFWSELKAIDWCPIYADPPLHGLPWLKSNDLVAAPNVVRPNLDMWMV
SSTMHVLDGECCSYVKCKLGWMDRPSVQVLSTQLVELSKSYCQLKLNSGVDSVFEVELQK
GIVSIYSMMQEYINSQDFMILKSALDSVSWVWIGDGFVAPNDLAFDSPVKFQPYLYVVPS
ELSSFRDLLLALGVKPNFEVSDYFRVLEKLHTDVKGSTLSDDQLCFVICVLEAVADCFSD
MSPAEVSSAHLLIPDTSGVLLYSKDLVFNDAPWMESSVAIDKKVVHPRISFDLASMLGVQ
SLSCMSLVDEEMAKDLACMDFTRISELLASYASNTFLLFDLLELADSCNTKKMHVIFDKR
EHPRQTLLQHNLGEFQGPSLLVILEGASLSREEVSSLQFLPPWRLRGDTLNYGLGLLSSF
SVSDILSVMSGGYYYLFDPRGLVLAPSLSHSHGAKLFSLTGTNLIERFRDQFSPMLVGQH
MMLSSEMTVIRMPLSPEFMTEEPESGFQKIKQMYDRFAEHGSRALLFLKSVLQVSLSRWE
EGNVQPSQDYLVSVDSPSARLRNPFSEKKWRKFQISRLFSSSNAATKMHVIDVSCHLGDS
KVVDRWVTALSMGSGQTRNMALDRRYLAYNLTPVAGVAVHVSRNGHPADISHSSCMMSPL
PLSTKVDMPVTIMGYFLVRHNRGRFLFKTREGYDDAGSQLIEAWNNELMACIRDSYIEIT
MEMQKLRRGSADDLSAGHSVHVALKAFSDQIYLLWPRSDMHSLNDEPDGSELVLQNVPKA
DWECIIERVIRPFYVRLAELPVWPLYSGNLVRVEEGMFLSQPGNGVGDNLLPTTVCNFVK
EHYPVFSVPWYLISELQLVGVTVREIKPKMVRDLLRVSSTSMVVRSVETYVDVLEYCLSD
IRLPESGSSEADIFCRLVDGSSTSLTSIRGLHGIPSHGSTNSGADALEMVSSLGKALFDF
GRGVVEDIGRTGSPMIQRDRMENVNGVSDSNTGNKYLSIAAELRGLPCLTAAKNLARLGN
TNLWVGNNDQQMLLQPLLGKFIHIGILDRPTLADIFSDVSLQSLLKLQKISLHLVANHMR
SLFHEGWVNHVINSNMAPWYSWDNSTNSGGEAGPSPDWIRLFWKNFDGSSDDLALFSDWP
LIPAFLGRPVLCRIRERGLLFIPPLSASTSSGSNVMELEPLQNLLNGLSIDHSSLSETVR
PYSLAFMEVHNRYPWLLSFLNQCNIPIFDPTFLDCAGPCDCLPSAGQSLGQVIASKLVIA
KRAGYFPELTSFPASDCEELFNLFVADFASNRSNYGREELDVLCALPIYKTVVGSYTQLL
GKDLCVIASNSFLRPFDEHCLSYTMDSDESLLLRALGVPELHDQQILVRFALPRFESKSQ
AQQEDILIYLYINWQELLNESSVLDTLKETRFVRNADEFSLDLSKPQDLFDPNDALLTSV
FSGERKRFPGERFTTDGWLQILRKLGLRSSTEADVMLECARRVAFLGAECIKQNQDIGKL
DEDPTDSNNELSSEIWSLAESVVEAVFSNFAVLYSNSFCNAFGKIDCIPSERGFPNVGGK
RGGRQVLSSYSEAILLKDWPLAWSCAPIILRPNLIPPEYAWGALHLRSPPSFSTVLRHLQ
IVGKDGGGDALAHWPTATNMMTVEDAACEVLKYLAKVWDSLSSADVQELEKVAFLSAANG
TRLVKASSLFVRLGVNLSPFAFELPSIYLPFVRILKDMGLQETLCVSSAKDLVLNLQKAC
GYQRLNPNELRAVMEILHFICDENDESKSERFDWHFDAVVPDDGSRLVHARSCVHIDSCG
SRFVKFINSSRLRFVHPSVPERMCLTLGIKRLSDVVVEELNAEVQTLGSIGPLSLEFIKQ
KLLSRSFQDAVFKILSSVKSNTLAFSSSSDQVKCLLEDIADKIQFVQSIYTRFLLLPDCI
DITYVPKDSTLPGWAVESKHRALYYVNKGRTLFLVAEPPSYMSVVDVITIVLSDILGSSS
PLPLGSLFLCPEDSESAVTDILRICSENNGRETMRNNSNLIGKDILPQDAHQVQFHPLRP
FYMGEVVAWRSQTGEKLKYGRIPEDVRPSAGQALYRFGVEIAPGVIETLLSSQVFSFRSV
TLDDEGSSVMLSEASGSASENTMHAQIPKESRKNNMMSTQLQTGKDLQYGRVSPAELVQA
VHEMLSAAGISVNMETQTLLRTNLTLQERLQDSQAALVLEQDKAETAAKEADTAKAAWQC
RICLSSEVDVTLVPCGHVLCRRCCSAVTKCPFCRIQVSRTMRIFRP
>Sgl78109 E3_adaptor/Cullin_RING/DCX/DWD 153.9 32.1
MNSVDETGELKHLQTLEGHTDRVWGLAWNPTFTNLLASCSGDKTVRIWERSFSGSFSCKA
VLEETHTRTIRSCAWSPSGKMLATASFDATTAIWENIGGDFECISTLEGHENEVKSVSWN
AAGSLIATCGRDKSVWIWEVEPGNEFECVSILQGHTQDVKMVQWHPSMDVLFSCSYDNSI
KVWAEDGDDDWHCVQTLNEASNGHSSTVWALSFNASGDKMVTCSDDLTIKVWGTDSLHAQ
SGDGVGPWKHLCTISGYHDRTIFSVHWSRDGVIATGAADNAIRLFVENDDDLVDGPMYKL
LSKKEKAHDMDVNSVQWSPSEKPLLASACDDGTIKIWDYAST
>Sgl78113 E3_adaptor/Cullin_RING/SCF/F-box 18.1 0.1
MAIINETENQIDQQKDEVEEEEEEEGRWKNLNTDVLALILKRFNNKADLCRFRSICKPWR
LFATPIQPHLLFPLILPPLHPKSRFFSLFPTTLYIFSPKLNQSNDFWLSKVAETGEKKWA
LLNPLTKHKLYYFSSGVFKQGINLVDFRNFEVGKSYRLQLISSFPGVEDKDSFDFEEFSS
SISLRKVVVRIEDTISVLGFFGYGEIGFWNLGDENWKIIENGKKKEKKHDFDDVICYGGR
FYAIDRTGKLMMIDPMAAAREEFVEVVCPQEECNGHYTYLLESNFKLYMVNKIVNPIPTS
YYNEEEGEWIMDKSSIGNPLGFKVLC
>Sgl78124 E3_activity/RING/U-box 24.4 0.0
MVTVMMMSQSHSQNSNNNNHQNHHNHHHHHQQQQQQQPSPLSLSPLSSAPPPQSAHHAVP
LSSFQAAEVLPARVRLSDIAPYDGAPCGAYLKAVEALCGSLMRHNAAVIELGSSDAAVMR
CGLESARLHFRSKAVKGSRGVYMYRAGRALEDSDSSPPCLAEIFRCLGKAARAVLCAIAR
HLRLRSDVFNHLLDDNPLPANEASSSVVVATYFHASMQNGKGAIGGGKPSVSGEFEKGLL
TLVSSDTPGIQVSMDSMHLDLSLDSSMLSELLWRGISYVIRERVPSGFTKRMALEDSDSS
PPCLAEIFRCLGKAARAVLCAIARHLRLRSDVFNHLLDDNPLPANEASSSVVVATYFHAS
MQNGKGAIGGGKPSVSGEFEKGLLTLVSSDTPGIQVCDPNGRWYLADSGFGSGSVLLLTG
KALSHATAGLRPAASYRAASDFFSGVGGVGRTSLAFRLMPQSNAILDCSPIAAAGHVIPH
SYVPISVSQFMDDLSAEEVTLGNHTDNTYVEQKDNMNNSNDDNNIKEPSLRSVLSDPLSG
VFLEDAMVVSCGHSFGGLLLRKVIEASRCMLCQTEIETRSLIPNYALRAAASAVRHEDDR
RLFHNAALRKRRKEIGDQIDLGRRINKDDGDVAPDSGMQRIQYPFSVNEKVVIKGNRRTP
DKFVGKEAIITSQCLNGWYLLKIVGSGESVRLQYRSLRKLTASRTSEDRGTSEPIQSSSR
EHNS
>Sgl78203 E3_adaptor/Cullin_RING/DCX/DWD 98.7 10.1
MEERDSSTATGGGGGGGGGANQLYPNFLLDKLLKKASVRQVSKNASPVEQFRRALLKGYE
VSVKEVDTLMSLLSEKKRKMEQEEAERNMQILLDFLHCLRKQKVEELTEIQTDLQYVKED
ISAVERHRVELYRAKDRYSVKLRMLGDDSAPKLWPSTADRSSGGVSSGSHSSLGGLAAGG
FQNKKMDGKAQGPHAPPRKDALGGLDSQHISQSGLAVMRKKRIHVQFNDLQECYLQKRRQ
LTGQPARQDERDSTFMQREGYSTGLAEFQSVLSTFTRYSRLRVIAELRHGDPFHSANIVS
SIEFDRDDELFATAGVSRRIKVFDFSSVVNEPAEAHCPVVEMSTLSKLSCLSWNKFTKNQ
IASSDYEGIVTVWDVTTRQSVMEYEEHEKRAWSVDFSCTEPSMLVSGSDDCKVKVWCTNQ
EASVLNIDMKANICCVKYNPGSNYHIAVGSADHHIHYYDLRNVSQPVHVFGGHKKAVSYV
KFLSTNELASASTDSTLRLWDVKDSLPVRTFKGHTNEKNFVGLSVNSEYIACGSETNEVF
AYHKEISRPVTCHKFGSPDLEDADEDAGAYFISAVCWKSDSPTLLTANSQGTIKVLVLAA
>Sgl78224 E3_adaptor/Cullin_RING/DCX/DWD 120.2 19.7
MPVFKTPFNGYSVKFSPFYENRIAVATSQNFGILGNGRLHILDLTPPSPSSSLSELTFFD
TADGIYDVAWSESHDNLLVSAIADGSLKLYDLSLPPPQNPTRSLAEHTREVHSVDWNPTR
RDSFISGAWDDTIKLWTVDRQTSVRTFKEHVYCVYAAVWNPRHSDVFASASGDCTVRVWD
VREPGSTMIIPGHEHEILSCDWNKYDECLLVTGSVDKTVRVWDVRSFRAPLTVLAGHGYA
VRKVKFSPHQRNVIMSCSYDMTVCMWDFMVEDSLIGKYDHHTEFAVGIDMSVLVEGLLAS
TGWDEKVYVWQHGTDPRAV
>Sgl78250 E3_adaptor/Cullin_RING/BCR/BTB 82.5 3.8
MSKPTPLITDLTDIDLDPEDFNSSLPIKKVPYGDAFEAARAGDVDRLRYLIESGINVNAR
DQWDSVALYYACLAGHLDAARMLLENGAICDEHTFDGDRCHYAALNLKVRKLLKAFEARP
PPLGPLQAALRETFLGCLANRAFLELSDCQPQFSGSSVLDGPDNSHFPPDVVFYVHGRPI
EAHRVILSARSPFFKKKFETDWKDRREVRFSREKLSYPALYSLLHFFYSDRLEVGVDDME
DLVRICKVCKCEALRSVIEKELLHQIFTEFKALRDIDSSQRRFILQGLSLPEEDRLPAAL
HNILHFSLANSSMKQNSDDVADNLAASVGRLQIQEHVNDLADICVRVDGRVFRCHQVVLA
SRSEYFKTRIFRMDDFLEVNNDLLVHTLPCLEEHDLSQEAFEKMIEYMYTDSLKDVEPQQ
AEELFDAASRYLLFPLKRAVADALLPHLETASPSELCHWLLLSDMYGVLKIREYCLDVMA
CNFETFVDTQVFRAMLLTLPPPSGDSSLRTTAPSAPGAGGHINQGNILDDLREKWLEVEA
GDLDERDESALLFDNRLEMLMQIAKQEQEQEKPDSIDEVVTM
>Sgl78267 E3_adaptor/Cullin_RING/DCX/DWD 21.2 1.0
MYLYSLTLQKPTGIVSAINGNFSGTTKQELVVARGKVLDLISPDENGKLQTLTSVEIFGE
IRSLSQFRLTGSSKDYIVVGSDSGRIIILEYNKLTNSFDKIHQETFGKSGCRRIVPGQYL
AADPKGRAVMVAACEKQKLVYVLNRDSSSRLTISSPLEAHKSHTITYSICGVDCGFDNPV
FAAIEVGYTEFDHDSSGVSVAQAQKHLTFYELDLGLNHVSRKWSEPIDNGANMVVTVPGG
GDGPSGVLVCAENFVIYKNQGHPDVRALIPRREDLPAERGVIIVSVARHKSLSFILVQTE
YGDIFKVTLEHGKDSKEGVAELRIKYFDTIPVTCSMCVLKPGYLFAASEFGDHALYQFQG
TGDEPDVESSSVNMMELETDEGFKPVFFKPRKLRNLIRVDKVQSLMPIIDMKVFNLFEEE
TPQIFALCGQGPRSSLRILRPGLGVSEMATSSLPGVPNGVWTVKKNVKDEFDAYIVVSFA
SATLVLSIGETVEEVSDSGFLDTTASLAVSLIGDDSLMQVHPSGIRHIREDGRINEWRTP
GKKVITKVGYNRVQVVVALSGGEIFYFEVDMTGQLMEVEKREMPGDIACLDIASVPDGRK
RARFLAVGSYDNCIRILSLDPDDCLQVLSLQSVYSPPESLLFLEIQASTGGEGGADHPVS
LFLNAGLQNGVLFRTVVDMVTGQLSDSRSRFLGLKAPKLFSVNVRGRRAMLCLSSRTWLG
YMYQGNFFLTPLTCGILEFAATFSSDNCAEGIVAVAAEALKVFTIDKLGETFDQTVLPLR
YTPRRFVLQPKRKLLVIIESDQRAFKAEEREAAQNECFQVGQDDNGNLHMEDVDDNELSD
EQYGYPKAEAQHWVSCIRVLDPRTGETISCLELEDNEAAVSICNVNFSDKECGTLLAVGT
AKSLQFFPKKSFDAAYIHIYRLVDGGKLELLHKTPVDGVPLALSQFQGRLLAGIGTVLRL
FDLGKKRLLRKCENRLFPSTIISLHTYRDRIYVGDIQESFHYCKYRRDENQLYIFADDLY
PRWLTASQHVDFDTMAGADKFGNVFFVRLPQDVSDDIEEDPTGGKIKWEHGKLNGAPNKV
EEIVQFHVGDIVSSLQKASLTPGGVECILYGTVMGSLGAFLPFSSRDDVDFFSHLEMHMR
QESPPLCGRDHMAYRSAYFPVKDVIDGDLCEQFPTLPVELQKKIAEELDRSPAEILKKLE
EIRGVPGILLRVFGWHWQEVTIRVKTRSLKMSLNHYTKRILKSLDLQTR
>Sgl78277 E3_adaptor/Cullin_RING/SCF/F-box 21.7 0.0
MEGRRKRVRKTATRLNHIHTHIKPQPPISSSSSDSKVPKQASSSNKLKMLNSKSSSSEEE
EEEEEEEVEVLEASDLPCSILIDILGRLPLKTLIDCRYVCKSWRSLLTESYFYRLYSHHN
PTTLIIQIKGNSLTTLKEMCLIHHQGHSAGSLVRKMRLTTTHSKPVQGVDQNLRYQLGNG
CNGLICLRDTRTREPSLVWNPIMGQFVVLPKPVTPTNEKVVAGFGFCGRTNRYKVVRIFR
GVNDPPEKRRAEVYDLGVGYKWREIGDVPFLIPSRIPGFFTNNSLHWILDCPNNNTDDNN
LIDSNNKLNMELVCGFDFLEEKFKAIVPPPIFSDNENKYHWSNLGIIGDCLSICAIDAKL
FRPDVQVWVMEEYGVSESWALRLSIRDLTVDWWDPYKWIQVTSCLRNGEIMMLCAHCYVL
AYNVQERRFRSVGVLDFPAIAHVPSLISLEDVLSDNLGTGSLNVHYL
>Sgl78297 E2/UEV 225.8 0.0
MTIGSGGSSVVVPRNFRLLEELERGEKGIGDGSVSYGMDDSDDIYMRSWTGTIIGPHNSV
HEGRIYPLKLFCDKDYPEKPPTVRFHTRINMTCVNPETGVVEPKKFGMLANWQREYTMED
ILTQLRKEMAAPHNRKLVQPPEGSYF
>Sgl78350 E3_adaptor/Cullin_RING/DCX/DWD 26.4 3.2
MWRKEEGVLKKVCTTWRAVSRSELLWQTLVRIVWNTTTLLHATWRDHFIYLHRTSRNFQV
RRCLYATLQSLDYPLVPAPGGGDEGGGGGDDQLPILCLRLALAHDHMAAGFSDGSLRLFH
LPSRLHVRTVRPLLRDRLGLFSRAVSGIVLQPRDDRLVFASLDGDIHVVSPLIGPTPARR
TYLGDVVNDGALVDFTGCGRFWVGLYAGVPGRTFRVWSAESEELLFMGGSLTDPESVMGW
HMLTELRPTDFIGRIRVAPHDLAVGATSLRALVLDLDEPIVVVGEQTSRRGIIVGSVDAN
DEMFVMADTRGVASVRYLRTLEELCRFSVSAALRDGGGPISLRGLLGCINTMYVVMWIGR
TVRVWDAGHGEYLYSLREGVDDATALAASNQYVVAASSDTTIHMWDFGAQFN
>Sgl78357 E3_adaptor/Cullin_RING/SCF/F-box 17.6 0.1
MSTELLHDDLLAEILIRLPAESLLKIKCVCKSWYSLISSSRFILAHVCHNRSKNPRILLR
SFNKADKKVSYKLCHDNECLDDIMTIDPPFMRQRNDFLRMVGCINGLVCLSDDTVEVTDS
VILWNPVIRRFLPLPKLELNVDSNDLGRSVFGFGYDSTNNDYKVIKIVYRKNPDFEARQV
EASIAIYRLSSCCWEVNGSASVPLLDSRQAYVNGVIHWLAYNKLVVGFAVESEAFSDTML
PETLQNANISDLAIASWCDLLSVFQNGFWSGRLCLWVMKDYGVAQSWVKQFVIESYVMVR
SLRRNGCVILENIGGKLVLYNSKTNQFEEFKIHVEGSIRGFHMKSYVESLVLSDRLDAKS
IP
>Sgl78387 E3_activity/RING/RING 30.4 5.9
MDNPEHFSNYSVDLMEFGSGNFGCKHYRRRCKIRAPCCNEIFDCRHCHNEAKDSFQVDAV
SRHDIPRHEITKVICSMCDVEQDVQQNCIQCGVFMGKYFCSICNFFDDDVSKFQYHCDEC
GICRTGGKENFFHCSSCGCCYPNTMKGTHRCMEKALHHNCPVCCEYLFDTTNEVSVLSCG
HTMHLECAKQMAQHYQYACPICLKSMCDMSTVWRKLDEEVASTLLPEECQRMVRILCNDC
EANSNVQYHVLAHKCPKCSSYNTKLI
>Sgl78415 E3_activity/RING/RING 27 0.6
MEPDSPPPILSPRHRILQRLATNGIPEEYLEDLQPGLVRFMKNNKHRTSEVISAVLPTDI
DIAEVASEGKMRSSKASDHPNLKDVYRESLLWIKWLMFEDEPSTALTNLANMSVGQRGVC
GAIWGRNDIAFRCRTCEHDPTCAICVPCFKNGNHKNHDYSIIYTGGGCCDCGDETAWKRE
GFCSKHKGAEQIQPLPDEIANSIGPVLDHLFSYWKDTLLVAENILKGDLTNEYDIDPRKV
ANEFSYVVVEMLLNFCNHSESVLSFVSKKLIGTVDFLPLVVRSERFLITDVTKKLHELLL
KLLGEPIFKYEFAKVFIDYYPVPVAEALRTSSDNVLRKYPLLQMFSVQILTVPTLTPRLV
KERNLLAVLLECLGEIMFSCCGEDGKFQVNKWCGLFDTCHRVMEDVKFVLSHSVVAEYVT
HERLDIVKVWLQILSLVQGLNPLKRETSIHVEEESDNAHLPFIMCNSIATIQLLLVKGAF
SVAESKVMDEDGSFEREKNNTDDGYVQRHAKVGRLSEESSICSSAVQNSISESSSQKLHG
NNDLSVPSSALQLIFESTKAIDSWLVGSNVVTSENACSKLSALKETLLKVKKRMNFLGSS
YGYAEINDHDHGSGALQVQSATNSCPMDMDKDSSPMETELSDEKDALFLLSLSDWPDIDY
DVSLQEISVHMPLHGLLSLNLKEALRHYCGEPGLTEKGDFINLNPLSHDHLDFFRKVLRG
CQPYGFSSFMMEHPLQSRVFCSQVRAGMWRKNGDAAILCFNWYRSIRWSDHELELDLFLL
QLCAAYAPADLYVRRILERFQLSNYLALDLKRSSEYEPVLMQELLTLIIQIVKERRFCGL
TASQSLQRELVGKLATGDATHSELVKSLPKDLSKLDQQQEVLDRIAQYSNPSGMNQGKYS
LQMQYWKELDLYHPCWNPRDLQVAEERYSRFCGVSALNTQLPKWLSIYQPLIGIARVATC
KTTLQIIRAVLFYAVFTDSFALAGTSAGYFSLERKSGHDGDCIMLVTVATEEIEVGLNIQ
SGHQCLLSLLVLLMRMHKKGNTGSSMEAGSFNISSLVEILLKKFGELDSHCMTKLQQLAP
EIVNYKIDETANSSSASDSEKRKIKARERQAAVLAKMKAEQSKFLASLKSSADEGSDNPG
SQKEKHASNVPQDSEPHVCCLCHDPNSSNPVSFLILLQKSRIVNFVDRGPPAWDQGMQSD
GLESSVSAYEGIDSSIRGANALSAESSSSSEFVQSVEGAIDEFATQAHPEELNAFIDYLK
SQYPELRKFNVRSKLAEKKAKSARSLELLEQDLFLSIHKDIRSIDGFDFLRKDEGENAAR
SVLLGKYVAALAKASKGPSQDNNLHRVESAVQISSSKRFGPSDCDGIHVSSCGHAVHQGC
LDRYLLSLKERLVRRMAFEGGHIVDPDQGEFLCPVCRRLSNSTLSAVPGDSRKLWEQPVD
ISSESLTTKKEESGSWKLGHGLSMIQAAASIVSRSEMIKSLPLKKNRKIRSNLEPVFQLL
SEMYFSGKQDTSSRSGRVSPAVLMWATLKYSLVSTEIAARCEKSSSSSRKGLSSLNDEFR
SSGGFILPLLLRIIQSNRSENVLDLLLRFRGLQLFSASICSGITYAMHHDGAITAEGKIL
CVLKGTNGEMLFPDMEFWDQASHPVIIHDPFSTLMWVLFCLPYPFLSSKESFVSLVHIFY
GVAVVQAIITYCLYSQCNVNDLGFHDCLVADIAKLAGNSVIAKKLFISKSIDPSCRVKDV
IDKLSLPYLRRCFLLWKLLKCSAISPSHSRVGEFDKSLDISDCQEASGTLGDMDEINELR
NMFEISSLDIVLNDGGLRSMTSKWFHHFSTAFEDQCVQRPLHLTPVVPFQLMRLPVVYQD
LVQRFIKVRCPSCDSVQDEPALCLLCGSLCSPVWKSCCSESGCQAHAASCGAGTGVFLLI
RKTTILLQRNKRQAPWPSPYLDAFGEEDVDMHRGKPLYLNEERYAALTYMVASHGLDRTS
KVLRQTTIGTFFMHLEKLYLLVKLWLKLVLTCSLIMRHEEVEQVKICLA
>Sgl78419 E3_adaptor/Cullin_RING/DCX/DWD 114.4 44.1
MAAMAMDTDENVKRLQIRFITQLEDQFKVPTNAIAVPSNLTRFGLSSIVNNLLKAVDSDW
EPEPFDFLINGELVRLSLEEFLLAKGISAERILEIEYIKAVVPRKHEEPRLHDDWVSSID
GSNPGFVVTGCYDGFGRVWKGAETCTQMLRGHSGALTSLCMIDAEGSDSGNKLHVATASK
DRTVRLWQFDAEDSRNNPTSITAYKVLRGHTASVECVSSQKSGKMVCSGSWDSTINLWQT
GLSDGDADFASVKKRKKSGVVSEAQAEGEAVSTLAGHTNCVSSILWAQDETIYSASWDHS
IRIWDVETGNATWSMFCGKPLNCMDVGGESSALVSAGGSDGTLRVWDPRRPGSLAPVYQF
SSHTNWISACKWHEKSWFHLVSSSYDGKVMLWDLRTAWPLSIIDSHSDKVLCVDWWKDNC
VVSGGADSKMCTATGISVK
>Sgl78475 E3_activity/RING/RING 30.5 7.1
MFSGRMLDTPFFDHKQAATPPPPSNDQLYPSSSSNHRSSFDANVVMIFSVLLCLLIFSIC
VNCFIRCVLKCLIMVTQERRRRNHHQQKLVSCGVDKRALKTFPVMKYSKEVKIQGLSTEC
VICLSVFKSGEKIRILPKCTHGFHVKCIDKWLTSHSSCPTCRQSMVDTCQKIIGCHDDQC
RQFTSSSSTAEMVSISIVPLEREDVISRY
>Sgl78480 E3_activity/RING/RING 30.2 7.2
MFSRRMLDTPFFDHKQAATPPPPPNDQLYPSSSSNHRSSFDANVVMIFSVLLCLLIFSIC
VNCFIRCVLKCLIMVTQERRRRNHHQQKLVSCGVDKRALKTFPVMKYSKEVKIQGLSTEC
VICLSVFRSGEKIRILPKCTHGFHVKCIDKWLTSHSSCPTCRQSMVDTCQKIIGCHDDQC
RQFTSSSSTAEMVSISIVPLEREDVISRY
>Sgl78485 E3_adaptor/Cullin_RING/SCF/F-box 15.2 0.1
MTAVVLKVVFPLLDGVDLASCMVVCKQWRNVAQDDYLWKCLCARRWPSLCKRPLQSTVSF
YKLYGTFYKRQRRRVLLPPRLSFNDLDFYIDVWTESQLIFSEVVPGPLLHTGINILPTVI
SDTLRCHLESPEYKMVLPVEPRFSVPVGQKTRVSVLVGRKDLNKFACIINKAMFDYVDRT
SFRALAFDYLDFSPAHPFISGIRAWISLLFTDDKNDEVADVFGIEMDFCDAASNEREVLW
LLDMLDWQ
>Sgl78492 E3_activity/RING/RING 25.5 7.7
MVSKWRKAKLAFGCIQIPRTNDDEIPSSSPISTATPSSVVSNNNNGHNPRRISDASAVTP
PTPSSSGGLRLSKSFPKSSKKTCAICLSTVISGQGHAIFTAECSHTFHFNCITSNVKHGN
HICPVCRAKWTEIPIQGQSSEVLRGKLRANSVNWNRDNPLVAALQQLPLPQPDYNHNVTP
TYRIGEPSVFDDDDLIDEQQISREHSADNASDDHSDRRIEIRTCPEVSSVSKSSSYENFT
VLVHLKAPIARTSNLDSNSPSGSQNSRAPVDLVTILDVSGSMAGTKLALLKRAMGFVIQH
LGPHDRLSVIVFSSSARRLFHLRRMTDSGRHQSLQAVNSLSANGGTNIAEGLKKGAKVML
ERKCKNPVSSIILLSDGQDTYTINGLAGAQSRTDYKSLLPSSIQQNTGTSSQIPVHTFGF
GVDHDSASMHSISENSGGTFSFIEDEGVIQDAFAQCMGGLLSVVVQELKLELQCVDPSLQ
LDSIKAGSYHARLMPDAKIGYINVGDLYAEEERDFLVTMNIPQTSCVSEMSLMKVNCTYK
DPITKELTTLGEIEVVKINRPDKAEDVVVSTEVDKQRNRLKAADAMSEARFAAELGNLVG
AVSILESCRQTLSESVSAQDPLCVGLLNDLKEMQDRMSSQQVYEDSGRAYVLSGLSSHSW
QRATARGDTTTILSQSYQTSVMTDMISRSQTMVLGRAPSPNVRPPRSLSGRPRPR
>Sgl78510 E3_adaptor/Cullin_RING/SCF/F-box 15.5 0.1
MTAVVLKVVFPLLDGVDLASCMVVCKQWRNVAQDDYLWKCLCARRWPSLCKRPLQSTVSF
YKLYGTFYKRQRRRFFFLLDCPSMTWTSTLMCHLESPEYKMVLPVEPRFSVPVGQKTRVS
VLVGRKDLNKFACIINKAMFDYVDRTSFRALAFDYLDFSPAHPFISGIRAWISLLFTDDK
NDEVADVFGIEMDFCDAASNEREVLWLLDMLDWQ
>Sgl78518 ULD/UDP/UBQ/UBQ_Other 45.1 0.1
MIEVVLNDRLGKKVRVKCNEDDTIGDLKKLVAAQTGTRPEKIRIQKWYNIYKDHITLRDY
EVHDGMGLELYYN
>Sgl78539 E3_adaptor/Cullin_RING/SCF/F-box 12.9 0.0
MEHKKAKSLIINGDKPSNNSDDAVSPQTVALIDHLIMDEILPRLPVKSLIRCKSVSKEWK
STISTLQFAKLHLKFSSSTRRQFLMFTEEYHKCDSFCLLPYRERNNVKDLVDLPGGLGYV
DCYELADSSNGVVCLYQRNDDGDDRGCYFTLWNPATREEHDIAAPKGVHVSEAYGFGYVE
SIDDYIIVASFGSGNYLFNKFRGLYMYSLKEGEWERVFGSYGYVRIQRRCWKWRTVRDKS
NEELIAKQLQRQGVLVGDIMYWGHNFWTRRKIVGFNVVSNELREYLTLDWQSEYDSLTLL
RVKGCLSLEGKKKNDGVLDFWILKNADDWSSWQKFFSVDPTSISFITLSETGKCLVRQSD
EFKLVEPCKGGLDCCEGNDDVNYSHMVIATDHVESLFSPFGTTNDETDHKEDTDEKEENG
NSKNLTTNNMLLEKNRYLSFSLKVENNGSTKKNDICGDSNDNDDDDYEDDDDDDDYDNED
VDDDVEAYAERETSDDERDYELSASDNDNNDDDDDDDDDFDDFDDI
>Sgl78580 E3_adaptor/Cullin_RING/DCX/DWD 65.3 5.0
MTRKFYVHRCTSLAWVPQGNGAFVVAHADGNFYVYEKASFIQGKDAPVDSSFSLIKDPAQ
FSVSHAKSNKSNPVARWHICQGSINRIVFSPDGSHLAVVGRDGFLRVYDFQKEQLVCGGK
SYYGAILCCAWSMDGKYILTGGEDDLVQVWSMEDRKVIAWGEGHNSWVSGVAFDPYWSPP
SSDSTGENVMYRFGSVGQDTQLLLWDFSMDELVVPLRRCPPGGSPTYSAGSQSSQWDSAV
PLGSLQPAPCTRDIPKLSPLVAHRVYSDPLSDLIFTEHYILTACREGHVKVWMRPGSSES
VSTDSETVSNSKEKPTIPNPSGVNGK
>Sgl78620 E3_adaptor/Cullin_RING/DCX/DWD 88.9 14.9
MYPRIAFREIGLPRKKSKENLDRFIPNRSAMDFDYAHYMLTEGRKGKENPAASSPSKEAY
QKQLREVFNMNRPRILAFKNKPPTPVEFMPQDYATVQPSKPVKPRRRIPQTSERTLDAPD
LLDDYYLNLLDWGSNNVLAIALGTTVYLWDASSSSTSELVTVDDDKGPVTSVNWAPDGRH
IAVGLNNSEVQLWDSAANRKLRTLKGGHRARIGSLAWNNHILTTGSMDRKIMNNDVRIRD
HIVETYRGHQQEVCGLKWSASGQQLASGGNDNILHIWDRSLASSNSATQWLHRLEDHTAA
VKALAWCPFQGNLLASGGGGADRCIKFWNTHTGACLNSVDTGSQVCSLLWSQNERELLSS
HGFTQNQLTLWKYPSMVKMAELTGHTSRVLFMVQSPDGCTVASAAGDETLRFWNVFGTPE
VAKPAPKAAPEPFAHVNRIR
>Sgl78621 E3_adaptor/Cullin_RING/SCF/F-box 16.3 0.0
MAMKKAKLSIIDDDKPSNNCEDDVVSPQTLASVDHLIMEEILPRLPVKSLIRFKLVCKKW
KSTISSLQFAKLHLNFSSSNRRHFIVFPTTDKFCGNEKCTSFCLLPYREFSNVKDLVKLS
GGVKDVHWYNIVDSSNGVVCLYQRNDFECEKGCFFTLWNPATGEDRDITSPNGVHASEAY
GFGYVESIDDYIIVASFGSGTFEYNKFRGLYVYSVRAGKWKRVFGSYAYLRMNPWCWKWK
TVRSKSDDEFLAKRLRGEAVFVGDTMYWIRGKVIGFDVVSNELEKYPRLDCQGEYRSLKL
FQVKGCLSLKGERENGVSDFWILKNSDDWSSWQKFFSVDFTNISLITLSETGKCLVRRSD
EFKLVDPCKEGLDCYQGNHDNFGRMVITRDHVESLFSPFGITETDDEEDTDEEEDTGEKE
DIDEEVDTNKKEHTDEEEDNTGIFNHLTTNKMSSENKWLSFPPKVDNNSGTEKFDFEGDS
DDYNDDDEDDDEAGYDYNEDLDDDSESYSEWETSDDERDYDPEYDGIYNNDDDDYVDHDD
DDY
>Sgl78622 E3_adaptor/Cullin_RING/SCF/F-box 14.9 0.0
MAMKKAKSAIIDDDKPSKNCDDDVVSPQTLALVDHLIMEEILPRLPVKSLIRFKLVCKEW
KSTISTLQFAKSQLNFSSSNRRHFIVFPDNAEFCGNENCGYFFLLPYSECSNAKNLVKLS
GGFKDVDWYDIVDSCNGVVCLYQQYDGRFERGCFFTLWNPATREDRDITCPKGIHVSEAY
GFSYVSSLDDYIVVASFGSGTSNYNKFRGLYMFSVREGKWERVFGSYALLRMAPWCWKWK
TVRAKSDEELIAQRLLGEALLVGDTMYWIQSSGKITGFNVVSNELKEYPRLDYVSEYRSL
KLFQVNGCLSLQGERGNGVSDFWILKNTDDWSSWQKYFSADLTNISLITLSETGKCLVRQ
SEEFKLVDPCMEGLKSCQGNGVNFSHMVITRDHVESLFSPFGTTETDEEVNTHEKEDTAE
EDNNGISIHVTTNNMLLENRLSFPPKVANISNTEKNDLCGDSNDRFNDDEEDDGESENDY
EDLDGDFEAYSEWETSDDECDYDSDYDSDDDHDDDDY
>Sgl78645 ULD/UDP/UFD/UBX 38.6 0.0
MLLFLLSSNPILLRLFLPPHPQPQPSSAIDEDADADADAEFIPQPSSSPSPSPSRSRSHS
PPSGVRSQYSLRSKRKSNKNSGKGEGRSSNSRRSGRVGGVRTLADLKNKKSTSDDSGSDS
DGDRPSQYFTGGQKSGMVVQDPSNDNHVEAIMDQAIRMGATEGPVDVHQPSSSSRSFTGM
ARLLSGETISSSPQEQAPPETVTHTITLWRNGFTVDDGPLRRFDAQENASFLESITKSEC
PNELAPADNKTAVQVSLVRKNESFAEPKKQKNAFTGVGRTLGTSSSTSSDPSTVVPAPMS
APPPVMGLVVDDKLPSTSIQLRLADGTRMVSRFNYHHTIRDIQAFIDASRPTRTGSYTLQ
IMGFPPKQLTDLDQTVGQAGLANSVVIQKF
>Sgl78741 E3_activity/RING/RING 24 13.1
MINENTISYENNLLLASILCLLLVILFVLLLHIYARWLLAEGHLCGTTLASIFSPTTRLR
RSHTSTSSTTYTYDITSISSCSYHTKGLDQKIIGSIPTFVYIPPSSSSEGVAALECAICL
SVFEEKEVGRSLPRCLHAFHVECIDMWLCCHSTCPICRAHVVVVDQVVEEDRVCGGDDVN
QTVVIREQDHHDRRLSTSVDQIVVQIIDDEQNVASSECSTLDYCSSTRILSSNNRV
>Sgl78759 E3_activity/RING/RING 24 13.1
MINENTISYENNLLLASILCLLLVILFVLLLHIYARWLLAEGHLCGTTLASIFSPTTRLR
RSHTSTSSTTYTYDITSISSCSYHTKGLDQKIIGSIPTFVYIPPSSSSEGVAALECAICL
SVFEEKEVGRSLPRCLHAFHVECIDMWLCCHSTCPICRAHVVVVDQVVEEDRVCGGDDVN
QTVVIREQDHHDRRLSTSVDQIVVQIIDDEQNVASSECSTLDYCSSTRILSSNNRV
>Sgl78905 UBD/UBC-like/UBD_UBC 103.2 0.0
MSCISRNYELPYYLSWSYLGIPYLQGPSETPYEGGVFQLAFAVPEQYPLQPPQVRFLTKI
FHPNVHFKVRALRLICLDILKNAWSPAWTLQSVCRAIIALMVHPEPDSPLNCDSDNLLRS
GDLRGFQSMAKMYTRLAAMPKKG
>Sgl78974 E2/UBC 67 0.0
MVELPDAYPYKSPSIGFVNKIFHPNVDEMSASVCLYVINQTWSPMFDLVNVFDVFLPQLL
LYPNSSDPLNGEAAALMMRGKVVYEQRVKVNGQRTKSNLWLEVSVLGGLKLKEKDSRNLN
SLINPSLLLKLEAISHAAELFRRRLEDYDCGDPIPVNILDSWSVRQVPILLFHCDPEERN
SCDSFCEGGLMNNAFEYILKSGGIQREEDYPYPGANGTCHFDKSKVAAKVGSGQLQLHAD
IHWWSLLPIHMFEEFGPWIAIGWLWIFRLIRLNTASRCISCRVVEL
>Sgl78992 E3_adaptor/Cullin_RING/DCX/DWD 53.1 6.1
MSPLSLTPEKNEIIGGNACTISSCGNFAVLGTEGGWIERFNLQSGMSRGSYLDKSERKSC
GHNGEVVGVACDSTNTLMISAGYHGDLKVWNFRERELKSRWDVGCPVVKIVFHRPNGLLA
TVSDDLIIRIYDVVARKMVRKFEGHNDRITDVCFSEDGKWLLSSSMDGTLRIWDIILARQ
IDAIQVDVAITAVSLSPNMDVLATTHVNQNGVYLWVNRLSYADSYASGKDILLVNLPSIS
AGENNEMIDAEEGNTNHLHVKEAARVPTFDQRMPDLVTLSLLPKTQWQSLINLDIIKIRN
KPIEPPKKPEKAPFFLPSMPSLSGDIMFKPSEVTYEELKDGDAEQKSDYVTDSPLSPFLQ
ALQYAVDSKNFSSFTDYLKGLSPSSLDMELRMFQIIDDDELLERSRQAVLSLDMLLDYFI
YEISCRHNFEFVQAVVRLFLKIHGETVRCRSQLQEKAQKLFETQCAVWQRVDSLFQSARC
MIAFLGDSQF
>Sgl78993 E3_adaptor/Cullin_RING/DCX/DWD 63.2 4.0
MGIFEPFRAIGYITSSVPFSVQKLGTETFVTVSVGKAWQIYNCAKLNLVLVGPQLPKKIR
ALASYRDYTFAAYGNKIAVFKRAHQVATWNYHSAKVNLLYLFGDHILSVDVKHHLCLWAF
KEINQKFEPISHIVLEGTPTCIVHPDTYLNKVILGSQEGNLQLWNVNTKKKLYDFNGWNS
PISCCVSSPALDVVAVGCADGKIHVHNLRYDEELVTFTHSMRGAVTALSFSTDGQPLLAS
GGTFGVISIWNLEKRRLQSVIKEAHDNAIISLHFFANEPVLMSSSVDNSIKMWIFDTSDG
EPRLLRFRNGHSAPPLCIRFYANGRHILSAGQDRAFRLFSVVQDQQSRELSQCHVSRRAK
KLRVKEEEIKLKPVVAFDCAEIRERDWCNVVTCHMDTSEAYVWRLQNFVLGEHILSPSDE
NRLQ
>Sgl79171 E3_activity/RING/RING 29.7 8.4
MQLRSNRILPEPSVPSDNVENDVGNAMAELNEALGVDFVMEDNDSEIDDEIVKETKKVGR
KRKKSSKKKGKIKKQSNDGVMDPAEREASRFEGISGFEFVDPVEMLKKVRKKKNGELKPT
LMWEVWEAEHSKWIDKYMTDDIDLDQQNIVMDEMVDEPSELATELLRFQKEWLAWALKQE
SSESRGGILADEMGMGKTVQAIALVLAKREIRRAVNGGDEFSSPSSSSMLPKLNGTLVIC
PASALSQWKREIERFTRVGSTKVLCYQGPKRVRSSLRFSNHDIVITTYNTIEADYRKVLP
PKIKCEWCGNCYSERRMAVHLKYYCGPNAKKTEKQSKQNKKNKKLNLKVLKTFSKDNVEV
NDDKQDAAQYKSEKVNNNNEGSEIQFEQEDLDDIEENVRKSVLHSVKWERVILDEAHCIK
DRRSNTARAVLALQSSYKWALSGTPLQNRVGELYSLIRFLQIYPYSYYMCKDCDCKTLDY
SFSLECKSCTHSSVRHFCWWNKNIATPIQLHGNYWRQRAMFLLKHRILKKILLRRTKSGR
ASDLALPSRAVLLRRDSLDIKEADYYQSLYNDSQAQFNTYVIEGTVMNNYAHIFDLLTRL
RQAADHPYLVVYSRSNTAKNVTGVETENGDQVCGICHDPVEDPTVTSCGHIFCRVCLIDF
SSSVGQPTCPSCSKPLTADFTSNSGTGERRSKTAVNGFKSSSIMNRIQLHDFQTSTKIDA
LREEIRLMIERDGSAKGIVFSQFTSFLDLIMYSLNKSGITCVLLDGSMTIAARDNAIRRF
HEEVDCRIFLISLKAGGVALNLTVASHVFLMDPWWNPAVERQAMDRIHRIGQYKPIRIVR
FIIENTVEERILKLQEKKELVFEGTVGGSSDALAKLTEADLRFLFVT
>Sgl79894 E3_adaptor/Cullin_RING/DCX/DWD 92.5 13.0
MRVKVISRPTDEFTRERSHDLQRVFRNYDPSLRPQEKAVEYVRALNAAKLDKVFARPFIG
AMDGHIDAVSCMAKNPSDLKAIFSGSMDGDIRLWDIASRRTVSRFLGHQGAIKGLATSTD
GRILVSCGLDCTVRLWNVPDPSVMHSDDSSEESPTPFGVYTGQNAYKAVDHQWGGNLFAT
AGARLDVWDHNRSQPVNSFEWGVDTVVSVRFNPGEPSLLATSGSDRSIAIYDLRLSTPAR
KIIMQTKTNSICWNPMEPLNFTAANEDCNCYSFDTRKLAEAKCVHQDHVSAVMDIDYSPT
GREFVTGSYDRTVRIFSYNGGHSREIYHTKRMQRVFCVKFTCDASYVISGSDDTNLRLWK
ARASEQLGVLLPREQKKHEYNAAVKNRYKFLPEVKRIIRHKHLPKAVYNAQNLRRTMTET
ERRKDERRKAHSGPSSVQKKPLRSRKIIKEIE
>Sgl79906 E3_activity/RING/RING 12.7 12.3
MNFPAFVVVNQRYWRDSLQPIDQESSYIQSDDFKVHGKRHACGDGVGSSRDGESFVKGGF
KCIYNEWRGLFGWYPDVRSILARAWREAGSTSLRSVPFVLIDDCRQQLQSDYVVVDLDES
NHPLPLTTVYQHMQPIQASPYTFLQALTGHEYPVGLLDVEKILPIEKEITAVGICSSKNG
VLEIKSCRDLPIFLSEWTKDQMVIELSSKTKILLWSGVIVGSVSIAVLGYAIVRNWNKWK
QWREQRRTQQENRAALSGEGGSSSSNEFEVAEEEEVEDVPEGQLCVICLMRRRRSAFVPC
GHLVCCQRCAFSVERDLAPKCPVCRQTIHGGDNRGYTSSCSILLFMAAIGTQANDTAELL
QQLSLESQTKSLEVHEPPKKFGSIGSRNTPNSMAKPYERSKEATFGFWSSIIKFGNCDLW
EVDHKARKEGWMFEIYEDKDGASLEKMELMTLEVRQRGIGCDAKVAYEFHVNSEENPEKN
YSQRRGWIQEKTVDKKLCAFDLLATVAGKLLEGEASQSTLEDKDELGIQDVVMEEQDEEN
LSRKDETCDKQNAAAASVNLELGLQVHDQDYCMKEIPFPQNDVFSAPTSVLTLSHCSEKD
DSLVKMDINNDKSEGSDPGHSDAFLSDVNKIVEQCDDKVEALSSNGPDMHSSKDLGFFDG
KPQLSSQIVALIYHWALTSTLVVQFHPVGIVIIL
>Sgl79952 UBD/UBC-like/UBD_UBC 110.2 0.0
MKLCPREVEKLALHNAGFLAQKRLASGLRLNYTEAVALIATQGPSETPYDGGVFQLAFAV
PEQYPLQPPQVRFLTKIFHPNVHFKTGEVCLDILKNAWSPAWTLQSVCRAIIAFMAHPEP
DSPLNCDSGNLLRSGDLRGFQSMAKMYTRLAAMPKKG
>Sgl79963 E3_activity/RING/RING 8.9 5.3
MECLHRFCRECIDKSMRMGLGIYCFYLCFLALEIVSFLLPIMIIMMNNECPACRTHCASR
RSLRDDQRFDQLIAVLYPDIRKFEEEEVAFYDEDEARNKQIQESITQVLIKQSEALGKKR
SSNKDAAGPSVTRSQRKQKNSHSRKRRRRKNSSIEYQDSDNSDDVIDSDKQFSTNEHHPE
VKLKRARSRVSIEVSQSPSATNLSRGSSDNNVEQNKEERNISPSLTIGKERLSWGRGGAR
SNTRHGNVNNGSTSRRRLRLSKLVDFVNNLEEVDDESALETPMKDENAQHISRQDQNDSL
AHQSLLQPSSCSNNKQTQVADLLQDTLHRLDREKTLPGAIASCISSGEQLVLAYSHTKEA
M
>Sgl79976 E3_activity/RING/RING 23.1 3.8
MGFCRRGERVLGFQWRKKLGFFSKVILGLLIFFVLFEPATSLRPLREKARSWGDEWLFVK
KEDSNMASFSSWNISGTYRGNWKFLDSANISSRFPDFQRSDGNSVIELMSTPTKITGVHY
VQGVIIFHDAFDDDHEGGGAQIRVEGVYIWPFRQLRMVANSGKDSEFSPEEDYLLSNPYH
LLGVFSSQVFQDSTRDKIWRRKKSQVQDIEKHCNIEIAAQVSRVASLQNDGDHDRYHLEG
LMESPSADEDGDCFSPLSLNGTSVNIEVYYNKAVNYTLMVTFVSFLQVLLLIRQMEHSNT
QSGAAKVSILMIGQQAIMDAYLCLLHLTAGILVESLFNAFATAAFFKFVVFSIFEMRYLL
AIWKASRPANSGEGWEAMRRELSLLYSRFYGLLLGGILIMYEFHNFLRPILLLMYSFWIP
QIITNVVRDSRKPLHPHYILGMTLTRLAIPLYIFGCPNNFMRIGPDKKWCICLCTFLGLQ
SLVLLLQHYLGSRCFIPRQILPEKYSYYRKFDQDGNHMTDCVICMTSIDLCARSNNDCMV
TPCDHFFHSGCLQRTIPRILPRVFIKQKKDDIHCSS
>Sgl80041 E2/UBC 95.6 0.0
MDMEVNYCNESLPSDSVIAKKLKQEKEVSTSDLMESTAVIDSVDNANAGKTLTSGSNNSV
DQNGSASDLSFQDDAIEDDEDYVDDDDMVSDYDDNNEFFYDNDDDDDDYLKLQAQFDNVD
LPPGVEASVPWLNDPSPSEKPVAVGTSTSSAQEEKVCASSSSSKAALSSKVKKEEEMDDV
LRKLMYFKQFDTVADCSDHHYLEMKSSQPSKTWIKKIQDEWKILEQNLPDTIFVRVYESR
MDLLRAIIVGPSGTPYHDGLFVFDAVFPSSYPQEPPMVHYYSSGFRLNPNLYECGKVCLS
LLNTWTGGREEMWVPNKSTMLQVLVSIQALILNAEPFFNEPGFERTYKGQEGKRKSQVYS
EDIFIKSLKKMMYTLRNPPQHFEDLVAGHFRVRALDIMTACNAYVEGAEIGCNVKEWLEK
GDAAPKTGSTNFKAEVAKTMKPLNKYFINNGSKDTEMFQS
>Sgl80066 E3_activity/RING/U-box 31.8 0.5
MEQCFEQPIARECCSGDDITKCKSPSAGVAGMVNNNSNSSGGFDCNICLDFVQDPVVTLC
GHLYCWPCIYKWMQSQITMFESSDQQPQCPVCKTQVSQSTLIPLYGRGQTSKPTTKFDVV
VPKRPNGPGCGVHTLVTATTSRSQQLHHDQQLHHRGYHRHQQQQVHPYYSVDDYQSPTLG
LAGTTTYNPMISMFGEMIYARIFGNSQTTLYSYPNTYSIAAASNARVRRHAMQVDRSLSR
VSFFLCCCIILCLLLF
>Sgl80203 E3_adaptor/Cullin_RING/DCX/DWD 41.7 6.1
MNGVDGGGGSGGGGGGGGEVSGLGPPPSPLDWKFSQVFGERAAGEEVQEVDIISAIEFDK
TGDHLATGDRGGRVVLFERTDTKDHGVNRRDLERTDYPISRHPEFRYKTEFQSHEPEFDY
LKSLEIEEKINKIRWCQTSNNALFLLSTNDKTIKFWKVQEKKVKKITDLNVDPSKAAGNG
SIVSSGVSSSSKPYLVNGGYPDKLPNSLNNESFSPGGIASLRLPVVTSCESSLHARCRRV
YAHAHDYHINSISNNSDGETFISADDLRVNLWNLEISNQSFNIVDVKPQNMEDLTEVITS
AEFHPSHCNTLAYSSSKGSIRLIDLRQSALCDSHAKLFEEQEAPGSRSFFTEIIASISDI
KFAKDGRYILSRDYMTLKLWDINMDAGPVATFQVHEYLRPKLCDLYENDSIFDKFECCLS
GDGQRVATGSYSNLFRVFGCAPGSTEATTLEASKNPMRRQVQTPSRPSRSLSSITRVVRR
GSESPGVDSNGNSFDFTTKLLHLAWHPSENSIACAAANSLYMYYA
>Sgl80307 E3_adaptor/Cullin_RING/SCF/F-box 22.5 0.4
MKKIKTNRSPIEEIPPEIMFDILSRLVTKTCLNCKLICKNWYQMIISQESGSAKKKRTDF
LLFDLDKSCKVDEDGSLIVSNNDAVFRFKSKLNLPHSNLSVVNECDGLICLACRRWKPYV
ICNLLTGKQVVVKKQWRDSCIRNSIYGMGCCI
>Sgl80320 E3_activity/RING/RING 33.3 7.3
MSSKLEEMDPPSTLLCDLRPYQKQALHWMVHLERGKTTDEAANTLHPCWEGYRLADKRGL
SVYLNSFSGEATVEFPSTLRMARGGILADSMGLGKTVMTISLLLSNSERVIPSSQLTPVE
SAEQSKTAGSSPDPFMKASKPQGLDKLMRQDNILIDGGSLIVCPMTLLSQWKGEIENHAQ
PGSLSVYVHYGQGRSRDPKVLAQYDVVLTTYGLLASEISSENSQGCAVLQSIRWLRVVLD
EAHTIKSTKSQVSVAASALTAGCRWCLTGTPIQNKLEDIYSLLRFLKVEPWGNWAWWNKL
VQKPFEEGDERGLKLVQSILRPIMLRRTKYTVDREGRPILVLPPANVQVVYCELTEAERD
FYEALFKRSKVKFDRFVEQGRVMYNYASILELLLRLRQCCDHPYLVMSRGDTQDYADLDK
LAKRFLRGGCGTADGEEKVAPSKAFIQEVVEELKKGEQGECPICLESFEDAVLTPCAHRL
CRECLLASWRNSASGVCPVCRNTVNKKDLITAPTDSRFQVDIEKNWVESTKVSSLLQELE
SLRSSGSKSIVFSQWTAFLDLLEIPFKRNNISFLRLDGTLSQRQREKVLKEFSEENDVMV
LLMSLKAGGVGINLTAASNAFVLDPWWNPAVEEQAVMRIHRIGQTKTVSIKRFIIKGTVE
ERMEAVQARKQRMIAGALTDEEVRSARLEELKMLFT
>Sgl80322 E3_adaptor/Cullin_RING/SCF/F-box 22.8 0.1
MKKIKTNRSPIEEIPPEIMFDILSRLVTKTCLNCKLICKNWYQMIISQESGSILVGKKKR
TDFLLFDLDKSCKVDEDGSLIVSNNDAVFRFKSKLNLPIAIYQW
>Sgl80339 ULD/UDP/UBQ/UBQ_PIM 73 0.2
MHIFVKARNTITLEVESNDVINNIKAKIHDKEGTPVDQQRLIFSGKQLEDDRTLAEYNVE
KDSTLHLSLRLRGGGYGTLKCYPPNLLVLAQKYKQNKKVCRKCYARLPLRATNCRKKKCG
HSNELRLKKVFQAKGV
>Sgl80362 E3_adaptor/Cullin_RING/DCX/DWD 59 16.5
MTVVSAHKFAQCITCHAWSPDHSMIAICPNTEEVHIYQAAADKWERVHVLQKHDQIVCGI
DWSSKMNKIVTVSHDRNSYVWNQEGGEWVPTLVILRLNRAALCVQWSPKENKFAVGSGAK
TVCICYYEQENNWWVSKLIRKRHNSSVTSVAWHPNNILLATTSTDGKCRVFSTFIKGVDT
RDGAGSSSDAKFGEQIIQLDLSYSWAFGVKWSPSGNTMAYVGHNSMIYFVDDVGPSPLAQ
SVAFRDLPLRDVLFVSEKMVVGVGFDCNPMIFAADESGLWSFIRFLGQRQTTPTSARAGS
QISGAFGKFYGQSKYNNADNDTSDARAHENCITCIVPLKTGRDSKVTHFSTSGLDGKVVI
WELGNQDIADYL
>Sgl80387 E3_activity/RING/RING 34.2 6.0
MKPHIRKLFPLQEDHNPTLFSSENNTHDSATHADNNNNSSSSSSTGCCYNNLKLNPPFDS
AMALTVLVLLTALFFMGFFSIYIRRFADESSVDPTRRRRGGENPNPAARTTYRSMSAKGA
DPTTVKALPVYAYCGGGAKQGIDEMECAICLSEFEEREWIKEIPYCGHVFHVECIDTWLA
SHVTCPLCRTAKLLVERHVDGGDKEVRVKEGEVEEREVRLVVHGGDTWSNREVEEREVGP
IRGERRSTSCLWCGDRVRLHRSLSF
>Sgl80393 E3_adaptor/Cullin_RING/DCX/DWD 19.2 3.5
MQMSPFPSQNGVDGDDERDDEEEYEDEDELSEELEEKEEEDEEPKLKYQRMGGSLSTLLS
NDAATCIAVSDRMIALGTHCGCLHILDFLGNQVKEFHAHKAAVNDLSFDLEGEFIGSCSD
DGSVVISSLFSDEKQKFEYHRPMKALALDPDYARKSLKRFVAGGLAGQLIYYTKKWFGYQ
EQVLHSGEGPIHAVAWRTSLIAWANDVGVKVYDTANDQRVTFVERPRGSPHPELLLPHLV
WQDDALLIIGWGTSVKIASLRGNQYGGANGSHKPVSTSIVRQVDIVASFQTNYYISGIAP
FGDSLAILAYIPGEEDGEKDFSSTAPPRQANAQRPEVRIVTWTNDELATDALPVHGFEHY
KAKDYCLSHTPLSGSNYTNGRWAAGDEPLYYVVSPKDIVIAKPRDAEDHINWLLEHGWYD
KALAEVEATQGRKELFEEVGSRYLEHLLAEKRYDEAAALCPKLLQGSGSAWERWIIRFAQ
LRQLPVLACYIPTENPKLSDTLYELALVALAMNPAHHKDFLSAVKSWPRSIYSAPTILSE
IEPQLRASMMSDNLKEALAELYVRTGQNEKAFSFFADLLKPDVFDFIERHSLHTAVREKV
VQLMILDTKRATTLLVQQRKVITPSDVVSQLLKAGDKCDFRYYLYLYLHALFEASPHAGR
DFHDMQVELYADYDSQMLFPFLRSSQHYTLEKAYEICVGKGLLKEKAFILGRMGNSKQAL
AVIINELGDMVEAVEFASMQNDDEIWEELIKQSTQNPEMVGMLLEHTVGNLDPLHIVNVV
PDGLEIPRLRDRLVKIITDYRTETSLRHGCNDILKADIVNLLVKYYKEARHAIYLSNEED
EARSKRDDNRMAESLTKAPSLRNMDLKSKTKAGGRCCMCFDPFSMLNVSVVVFFCCHAYH
MTCYMDSLNQFNDEKEAQNGFLDSDQDDYDDEENGERQSDSSRMRCILCTNAAR
>Sgl80394 E3_activity/RING/RING 42.5 6.2
MDALGSSWWSSHPFRHFHERGIKRRKNDRNSNRKPSSSSSSSNSSIQSNAAFHFPLKQAV
TAGSLALTGDTIAQLRNRCSSLSSNSSHDSDDKEFIQNLFSSHDWIRALRMASYGFLFYG
PGSFVWYQTLDRFFPQPTVKNIMTKVLLNQIILGPAVIAVVFAWNNLWQGKVSELPKKYQ
KDALPTLLIGFRFWVPYSVLNFWAVPLQARVAFMSFGSIFWNFILSSTVSNVSIDGVTED
YHYGNGFALPLTKDMVHRLDTGHMTKDLLYDPLVYQGNSDDLASFVCNGPRLIVLRVILG
TCVLLNQISVSSLGFLSCNTSHNNEQQPGQRMSPRLLTPPSHGLTPRFNVPESMQVPTEI
PRFNVPESMQVPGEIPRFNSPESMQEPTENNESKLTKQEQGNVLSKLKKEIYNPMPKILA
KRVSLYYRELNRDPNTKATEKHRDEDKKSCAVCLEDFEAKEEVMVTPCSHMFHEECIVPW
VKNHGQCPVCRANFIEKRQNQNALPFNNNSRSSSSNNNNNNNNNSRRQVVYQPAGQRVLF
GDEILSLIQAMDEAFPWRM
>Sgl80448 E3_activity/RING/RING 10.7 18.4
MVRDGEGCGGGGDWDVLGFEFGSMVEGLMVSTIFGEVMLYSVTLYPIHFRHPGRVGPSGL
IQPRSSFLVSLCLFTVSVFSSSSSQKSFLQRNWNLNWNSRICQRHKGRFPGLEEMTPVCP
FVKAARPDDASSKRSGDSQCKHAAEHESKSKNESSDSSIIEPKCPLGYDSRSFKIGPLSC
VLCKALLFESSKCVPCSHLFCKACILRFKDCPLCGADIEKIEPDEELQKLVDKFIDGHAR
IKRSPVSTDVEEKIIDKPVIYEDVSLERGAFLVQQAMRAFRAQNVESAKSRLSICAVDIR
EQLKESGNKPELCSQLGAVLGMMGDCCRSMGDAGSAVTYFEESVEFLSQVPTEDMEIIHT
LSVSLNKIGDIKYYDGDLQASRAYYFRSLDVRRSALKNHCDSASLTLDVAVSLAKVADVD
RGLGNEEGAIAGFREAVNMLECLKIDSSQIALEQRRQSVLEFLNSQIAADKQSDQTE
>Sgl80462 UBD/UBC-like/UBD_UBC 169.8 0.0
MANSNLPRRIIKETQRLLSEPAPGISASPSEENMRYFNVMILGPSQSPYEGGVFKLELFL
PEEYPMAPPKVRFLTKIYHPNIDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPD
DPLSENIAKHWKSNEVEAVETAKEWTRLYATETAMFGAKLANSIATFVTLAEHHNS
>Sgl80470 E3_adaptor/Cullin_RING/SCF/F-box 17.4 0.4
MLALGFGYAYNMFDDLLVREKRVESFFEGGGRCGGPGAFECLTGGGYGAGVGWDEARHDQ
MVGRRCKRRRNMNQLHKQRKMVLLPDEIIVNEILPRLPVKALLRFKVVCKQWNTTISSES
FAKLQLYNKNPHDQNLLLINLNFATSDSVLYKLNHLETTENLTTNKYSSVNIYIWNPATR
QRHPIPFDVTQFHNLDYRDGLFGFGYVSATHEYKLIMGNLKGDWYVYCTTNNGSNESKCG
WRRCLHYYHPTPHEESVVLSKQVGVLVGEKLHWKGAYFVVCFDLASEKYSHIPIPRTTWG
EWVVSQPRSWSDSPWIQNKIRDRFDNSMLCKFGGCLSLCVIDEYVGTFNLWKFMDSPTSP
NAPNWSKVVTMWCDSGKYLSSRSGGNLLLNPYANTIQVADTGKFLVFTKDKTLLLCDPRR
NILNCYKLLALKKDGSQKAGGSKPSQKAPPSSTPTPKLMDDVANNCFQVMQGVITAKERF
LAREKKLCKAEGKLAEMTTEIEDLKRSIVDLRRTNADLGVKFAKELMVSEGLKLRNIELA
TYTRKIKADMLDSGSYWVRKARYELLKQFKEGRVENWKVDEEIGEYEARTATMAEPCVED
NFPLPELD
>Sgl80475 E3_adaptor/Cullin_RING/SCF/F-box 13.2 0.0
MLEVVSKRPRPTDCMNDSSRKCRKRKKRKRGKMDKISELPEHLLHQILTRLHSKDAARTS
ILSKTWKEIWDSYQVLDFDLRCDYNVSDDLKELYKNQIYRLQRIQKLRLCFTKSTGLTID
DVYDWIGAAIDRGVRELEFQVKGIDNLSLPSRVMHGNSITALNLQGCNIRTYFINLPQLQ
KLSLKNLNIYPGDFEDLIAGCPYIEDLRLIQCAGLKKLSISNLDRLKRVDLHKCLLLRNV
VIKVQSLETFWYYSDKKKKNCEINIEECRALRELTVEYPRMTDEVFHGKIYELGELEKLV
LSRCNGLKSIALSGGKLRNLVIRRCRNLKEARCNTPNLTSLEYTGQRMPLLFTDLHKLNK
ALLSFDRSSTAAAKWKGGGDDASRLTSFLHQISYNNGLKSMSVNELDTVIYEDIRAMLLP
LHYISNPWAVQISLHFQDLLDTALKNSPFPSTLSIMSHVNSDFPEIIHRKLMKEKAAPQC
CGCFMNKCWRHYLKNVSIEKWILDTTELQKPSEFHDWKKSTFRLEWKC
>Sgl80522 E3_adaptor/Cullin_RING/DCX/DWD 128 12.6
MNEGREAVKTPLEARRSSMTTKRAYKLQEFVAHTSTVNCLKIGRKSSRVLVTGGEDHKVN
LWAIGKPNAILSLSGHSSGIDSVGFDSSEVLVAAGAASGTIKLWDLEEAKIVRTLTGHRS
NCISVDFHPFGEFFASGSLDTNLKIWDIRRKGCIHTYKGHTRGVNAIRFTPDGRWVVSGG
EDNTVKLWDLTAGKLLHEFKSHEGQVQCIDFHPHEFLLATGSSDKTVKFYDLETFELIGS
AGPETSGVRCMAFNPDGRTLLCGLHESLKVFSWEPIRCHDTVDVGWSRLSDLNVHEGKLL
GCSYNQSCVGVWVVDIARIEPYSVRARSNGHSELKSVSSGNLSVQNDNTSKVGSGRLSTL
QNSDMAEKETKPSGRFLVPANANQGNKDSRISPNPGGIPGTPHRVSQSTSPRNTLAPTTI
VQKRNSSKTHLVTIASTNSKPDVMPIIVPRDDVRPEQTEFKREVFSRRTITHHSQSKPAE
LRRFSNASEESDGPTINPQPEITTVKAPETSGVENKSVLPAVRNLNIHFPVVERNPKEDR
CVGSLKAENNSSLQPLGSSPLDNYEVRVPRTSKVSASSENQRPGKTRSLVANWEKREKSP
SSEGPTTSNSSVSVNVDSRPMNMNTKPRGYSLSAEKDMPSMTDDDIIVQIIGRHDQFLGS
MQSRLGKLQAVHRFWDRNDVKGAIGAMEKMADHSVIADVVSLMIEKTDIVTLDICVCLLP
LLANLLESDMDRYLGISLDMLVKLVRVFGAVIYSAVSASSSVGVDIEAEQRLERCNLCYI
ELERVKRCLPALMRRGGSVAKSAQELNLAISAACE
>Sgl80526 E3_adaptor/Cullin_RING/DCX/DWD 129.9 20.7
MSSTQTQQQQPQPAAAYQPYRLCKTLATHKRAVSSVKFSNDGELFASGSLDQTIALYSSQ
TLTLISLLVGHTDGISDLSWSSDSHYLVSASDDTTLRIWDARASSHDCVKTLRGHSDPVF
CVNFNQPSNLIVSGSFDETIRVWDVKTGRTVHVLRGHSLPVTSVSFNPDGSLIVSSSHDG
SCKIWDTATGTCLKVLIDDEIGVSFAKFSPNGKFILVATLDNSLVSISSFFFFKIFF
>Sgl80540 E3_activity/RING/RING 18.7 6.6
MSDAGDHQRGIGECTRRFYSLFSGWVCSLTFKQLAALVKPTSSSSYFNFPMDQGNPSSAF
TDEDVVDISSDDEDKEAHIVPPPPGHMSASASKRRLPNWVDSDEGESTPSTSYGTNNGTT
LGNGSSFPSRKYDENSYWNNSSHAHAEHQQHRNKRLLPPSIQASGSNAKQRNSWDNLGNN
RGYFTKGSDGDAYMYDNNHPRILPHTLVRGKPGSSGDYNTTSDLYQTTGVGEENISGEER
IIFQAALQDLNQPKAELDIPQGLLTVSLLRHQKIALAWMVEKETRTLHCLGGILADDQGL
GKTISTIALILKQWPAQMKSKSEKHDNNFAEALNLDDDDDDNPGNKEEDPNAGKCKSAEV
INIEPELYNLDDDDDDDDGSGSMETVKKVENDDGLKSNSGSSSSHPKVQGKRPPAGTLIV
CPATVLRQWARELGEKVAKKANLSILSYHGGSRTKDPKTLAKYDVVLTTYAIVSNEVPKQ
PIVDEDDGEEKPGDRYGLSSDFSGSKKRKHASTNKKGKKGKKKADSSLFSQAGPLARVNW
FRVVLDEAQTIKNHRTLAARACCGLRAKRRWCLSGTPIQNSVDEMYSYFKFLRHDLYSSY
KKFGEKIKNLISRDPNMGYKKLQAVLRTLLLRRTKETLLDGEPIICLPPKTIEMKSANFT
VEERSFYAQLEAESRSQFKAYAAAGTVNQNYANILLMILRLRQACDHPLLVKGFSSGSAR
KTNLENARKLPRHLLTELLNHLDAASAICQICSDPAEDAVVTICGHVYCHQCVAYYLNGF
DNVCPARRCKEQLNDDVLYSEATLKCCLYGDDVDGKSVNDDGCSNNPSILSTEYSSSKIK
AALEILLAHYELNSKYIENDEFGGTSAGNSISAQVRIEKMENSSSQGPIKTIVFSQWTRM
LDLFEYSLNLYCIPYRRLDGSMSLAARDRAVREFNTIPEVTCMLMSLKAGNLGLNMVAAC
HVILLDLWWNPTTEDQAIDRAHRIGQTRPVTVSRITIKDTVEDRILALQEEKRKMVASAF
GEDHVAGPGARLTADDLRYIFLGSRGI
>Sgl80567 E3_activity/RING/RING 29.6 8.0
MSSAGVAIAIPQSYFCYQCNRTVTLIPPPNSDLSCPNCSGGFLEETPQNPNPNPIPHPHP
FASSSPFYPDPLSLFADPSFSPSLNSRSRGPFVLSSTSIDLENPRNFSPFPPPNAEGFRP
FDFLQNYIVNLRQRGANVQFVVENHGDDPNFRLPTNFGDYFLGPGLEQLIQQLAENDPNR
YGTPPASKQAIDGLPNVVITAEVVNSDSNSCAVCMNEFEVGLNAKQMPCKHLYHSDCLIP
WLQLHNSCPVCRYELPTGDPDYDNQRANNRQGGGSSEEGTGNGGAQVEGGGSESGNGSGN
ERRFRISLPWPFRGFGGNNDGNNSGPSAGGQQGGGSGGQGSEPRQESLD
>Sgl80569 E3_activity/RING/RING 37.6 5.0
MDENSKVIDGGAAKTPADNSATLNPNPNPNPNPNSDVTITNSDVDGGSDGGGGGGGGTLP
QQNQSSRTPFTNLSQVDADLALARTLQEQERAYMMLSMNGGGGVGFGRWETGIYIPDDDD
DDFGDSHEYDDEDEDVDEDDEDNEEFIDNYDDDDEDAFDIHAHDDSGDDDDATNVELDPS
AYPDDEAYARALQDAEEREMAARLLAMAGISEREIVDLDEDHGGHSQDTWEEVDPDELSY
EELIALGDVVGTESRGLSADAIASLPSTNYKSKNNNETETDSCVICRLDYEDGDAMITLP
CKHIYHSDCINNWLKINKACPVCSTEVSTSGNSK
>Sgl80573 E3_adaptor/Cullin_RING/SCF/F-box 18.5 0.0
MEIMNNKKLKKEEEASKKDRISELPDSILLHILSYLPAKDALLKASFLSKRWTPLRPFLP
SLVFVQPTRPPTSSGVDFDRNWASFVDSTLIRIDFRHLTRFCVAFRYISTKDGNNATRSH
GRDELDHRSQVDTWIQGLRR
>Sgl80607 E3_activity/RING/RING 12.1 13.6
MDSNSIFLEDFGQKVDLTRRIREVLVNYPEGTTVLKELIQNADDAGATKVCLCLDRRSHG
VDSLLSNSLAQWQGPSLMAYNDAVFTEEDFVSISRIGGSNKHAQAWKTGRFGVGFNSVYH
LTDLPSFVSGKYVVLFDPQGVYLPNVSAANPGKRIEYVSSSAISQYKDQFFSYCAFGCDM
RNPFNGTLFRFPLRNADQAAESKLSRQAYSEDDISSMFTQLYEEGVFSLLFLKSVLSIEM
YVWDVGDTEPRKIYSCSVSSVNEDIISHRQLLLRLSKLSSISTFEMDSFMLDFVSEAING
SSIQKRTDTFYIVQAMASASSRIGSFAAKASREYDIHLLPWASVAACLSDDSTNGDALKI
GQAFCFLPLPVRTGLTVQVNGYFEVSSNRRGIWYGEDMDRSGKIRSIWNRLLLEDVVAPM
FRNLLLGAQGILGPTKSYYSLWPAGDFEEPWSILIQHVYKNVVQAPVLYTDAGGGKWVSP
AECFLHDEEFTDKEELADVLLQLGKHIVRLPNSLRYMLLKSITDFEQKVITPDAVRCFIR
ECGSLSSLGSAQRLLLLEYCLEDLLDSDVGRYAKNLPLLPLANGGYGSFSEASDGSSFFV
CNELEQKLLHQIPDRVIDGNIPNKIMKRLLAVADCSGANLIVFKPECLVQLLDKFLPPVW
KFKSKVFWEHGPGQNNHPTQSWFVLFWQYLSHQCENLSLFHEWPILPSTSQHLYRLSKQS
KLINVENLPERLKCVLVKVGSKILDTQYGVEHPDLSYYICNATGSAVMESIFDVISSSGG
VLQNCFHVLEAEERNELRNFLLDPKWYIGGHMSDSDTWKCKKLPIYRVYGEESDNLQFSD
LVDPQKFLPPKGVLKFFLGTEFILTSSDIEENILQRYYGLQRMGKAHFYRRQVFGMIKDL
PAEDRDSVMLSVLRDLPHLCIEDSSFKEVMKNIEFVPTHTGAIKYPGSLYDPRNEELLAL
LEDTDLFPCGVFHESEILDILQGLGLRTSASLDTVIQCARYVERIKEKDPEKAYMKAKVL
LPYLEANAHRWAAIPLNDEQGALNRVFSRAAVAFRPRNPKSDLEKFWNDLRMICWCPVIV
SAPYQALPWPSMSSVVAPPKLVRPKTDLWLVSASMRILDGECASTVLSYQLGWSSPPGGN
VVAAQILELGKNNETVTDQAFRQQLALAMPRIYARLTDIIGSDEMDIIKAVLEGCRWIWV
GDGFATVEEVVLNGPIHLAPYIRVIPIDLAVFKELFLELGVREFLNFSDFANILCRMASR
KGDEPLTAEELTAAILVVQHLAESPFPEKHVKIYLPDASAQLLPASDLVYNDAPWLLGLE
DSDSISSHASNILLSARRSVQRFVHGNISNDVAEKLGVCSLRRSLLAESADSMNLSLSGA
AEAFGQHEALTTRLKHILEMYADGPGILFELVQNAEDAGASEVTFLLDKTQHGTSSLLSP
EMADWQGPALYCYNDSIFSPQDLYAISRIGQDSKLEKPFAIGRFGLGFNCVYHFTDIPSF
VSGENLVMFDPHACNLPGISPSHPGLRIKFAGKRILEQFPDQFTPFLHFGCDLQNQFPGT
IFRFPLRTASTAPRSQIKQEGYAPEDVLSLFSSFSKVVSETLLFLRRVKSISLFVKDGSD
TEMQLVHRVQRHTVLEPERPPHALQYMFDYLDGIQLCKVDKNQFFEKLSRYGGEDLPRRL
QKVIVREQTSLDTTSHAWMMSECLGRGQDKSVDAKSRSHKGLPWAAVAAYLHSTKVDGDS
CVSALSEGSLATISSTSQDVELNTKCLKNFEGRAFCFLPLPISTGLPAHVNAYFELSSNR
RDIWFGNDMSGGGRKRSDWNIYLLEHVAAPAYAHLLETLATEVGSCEGFLSFWPTKLGGE
PWSSVVRKLYMYIADFEIRVLHTKAKGGQWISAKQALFPDFTFEKMPQLVDALSDVGLPV
VIVSQTLVELFVEVRPSLHFLTPQLLRMLIRRKCKFTERSALILTLQYCLFDLEKPVQCN
CLYGLPLIPLANGLSTTFNPRGVDERIYIAHGNEYDLLKDAIPTQLIDREIPEDVYMKLY
DIAQNEESNVSFLTCHLLEKLFLRILPAEWRNAKQVKWIPGHAQQPSVEWMRFLWNYLSS
SCDDLSVFSKWPILPVGKDNLMQLVENSNIIEDEGWSENITSLLLKVGCLFLRSDFPIEH
PQLKHYVQSPTAAGILNAFLAIAGTIENVDELFADSSEGELHELRNFILQSKWFSEINML
GKNIEVIKCIHMFESCRSRKLVSLNKDIKWLKPSGVREDLLDDDFVRAESEREKMILSTY
LDVQELSKAEFYKQYVLNRMSDFLSSQGALSAVLHEVKLLVDEDASVKDAISNAPFVLTC
NGSWRQPSRLYDPRVPELRLLLHTEEFFPAKEFSDPGTLDMLSCLGLKQSLGYTGMLDCA
RTVSLLNASKDLETIAHGKRLLACLDALGAKLSIEEGEESSKVFGEGPVSLHVKDDCDID
SVLGNLNDAQPQEEFWSELKAIDWCPIYADPPLHGLPWLKSNDLVAAPNVVRPNLDMWMV
SSTMHVLDGECCSYVKCKLGWMDRPSVQVLSTQLVELSKSYCQLKLNSGVDSVFEVELQK
GIVSIYSMMQEYINSQDFMILKSALDSVSWVWIGDGFVAPNDLAFDSPVKFQPYLYVVPS
ELSSFRDLLLALGVKPNFEVSDYFRVLEKLHTDVKGSTLSDDQLCFVICVLEAVADCFSD
MSPAEVSSAHLLIPDTSGVLLYSKDLVFNDAPWMESSVAIDKKVVHPRISFDLASMLGVQ
SLSCMSLVDEEMAKDLACMDFTRISELLASYASNTFLLFDLLELADSCNTKKMHVIFDKR
EHPRQTLLQHNLGEFQGPSLLVILEGASLSREEVSSLQFLPPWRLRGDTLNYGLGLLSSF
SVSDILSVMSGGYYYLFDPRGLVLAPSLSHSHGAKLFSLTGTNLIERFRDQFSPMLVGQH
MMLSSEMTVIRMPLSPEFMTEEPESGFQKIKQMYDRFAEHGSRALLFLKSVLQVSLSRWE
EGNVQPSQDYLVSVDSPSARLRNPFSEKKWRKFQISRLFSSSNAATKMHVIDVSCHLGDS
KVVDRWVTALSMGSGQTRNMALDRRYLAYNLTPVAGVAVHVSRNGHPADISHSSCMMSPL
PLSTKVDMPVTIMGYFLVRHNRGRFLFKTREGYDDAGSQLIEAWNNELMACIRDSYIEIT
MEMQKLRRGSADDLSAGHSVHVALKAFSDQIYLLWPRSDMHSLNDEPDGSELVLQNVPKA
DWECIIERVIRPFYVRLAELPVWPLYSGNLVRVEEGMFLSQPGNGVGDNLLPTTVCNFVK
EHYPVFSVPWYLISELQLVGVTVREIKPKMVRDLLRVSSTSMVVRSVETYVDVLEYCLSD
IRLPESGSSEADIFCRLVDGSSTSLTSIRGLHGIPSHGSTNSGADALEMVSSLGKALFDF
GRGVVEDIGRTGSPMIQRDRMENVNGVSDSNTGNKYLSIAAELRGLPCLTAAKNLARLGN
TNLWVGNNDQQMLLQPLLGKFIHIGILDRPTLADIFSDVSLQSLLKLQKISLHLVANHMR
SLFHEGWVNHVINSNMAPWYSWDNSTNSGGEAGPSPDWIRLFWKNFDGSSDDLALFSDWP
LIPAFLGRPVLCRIRERGLLFIPPLSASTSSGSNVMELEPLQNLLNGLSIDHSSLSETVR
PYSLAFMEVHNRYPWLLSFLNQCNIPIFDPTFLDCAGPCDCLPSAGQSLGQVIASKLVIA
KRAGYFPELTSFPASDCEELFNLFVADFASNRSNYGREELDVLCALPIYKTVVGSYTQLL
GKDLCVIASNSFLRPFDEHCLSYTMDSDESLLLRALGVPELHDQQILVRFALPRFESKSQ
AQQEDILIYLYINWQELLNESSVLDTLKETRFVRNADEFSLDLSKPQDLFDPNDALLTSV
FSGERKRFPGERFTTDGWLQILRKLGLRSSTEADVMLECARRVAFLGAECIKQNQDIGKL
DEDPTDSNNELSSEIWSLAESVVEAVFSNFAVLYSNSFCNAFGKIDCIPSERGFPNVGGK
RGGRQVLSSYSEAILLKDWPLAWSCAPIILRPNLIPPEYAWGALHLRSPPSFSTVLRHLQ
IVGKDGGGDALAHWPTATNMMTVEDAACEVLKYLAKVWDSLSSADVQELEKVAFLSAANG
TRLVKASSLFVRLGVNLSPFAFELPSIYLPFVRILKDMGLQETLCVSSAKDLVLNLQKAC
GYQRLNPNELRAVMEILHFICDENDESKSERFDWHFDAVVPDDGSRLVHARSCVHIDSCG
SRFVKFINSSRLRFVHPSVPERMCLTLGIKRLSDVVVEELNAEVQTLGSIGPLSLEFIKQ
KLLSRSFQDAVFKILSSVKSNTLAFSSSSDQVKCLLEDIADKIQFVQSIYTRFLLLPDCI
DITYVPKDSTLPGWAVESKHRALYYVNKGRTLFLVAEPPSYMSVVDVITIVLSDILGSSS
PLPLGSLFLCPEDSESAVTDILRICSENNGRETMRNNSNLIGKDILPQDAHQVQFHPLRP
FYMGEVVAWRSQTGEKLKYGRIPEDVRPSAGQALYRFGVEIAPGVIETLLSSQVFSFRSV
TLDDEGSSVMLSEASGSASENTMHAQIPKESRKNNMMSTQLQTGKDLQYGRVSPAELVQA
VHEMLSAAGISVNMETQTLLRTNLTLQERLQDSQAALVLEQDKAETAAKEADTAKAAWQC
RICLSSEVDVTLVPCGHVLCRRCCSAVTKCPFCRIQVSRTMRIFRP
>Sgl80615 E3_adaptor/Cullin_RING/DCX/DWD 200.7 43.5
MNSVDETGELKHLQTLEGHTDRVWGLAWNPTFTNLLASCSGDKTVRIWERSFSGSFSCKA
VLEETHTRTIRSCAWSPSGKMLATASFDATTAIWENIGGDFECISTLEGHENEVKSVSWN
AAGSLIATCGRDKSVWIWEVEPGNEFECVSILQGHTQDVKMVQWHPSMDVLFSCSYDNSI
KAVLEETHTRTIRSCAWSPSGKMLATASFDATTAIWENVGGDFECISTLEGHENEVKSVS
WNAAGSLIATCGRDKSVWIWEVEPGNEFECVSILQGHTQDVKMVQWHPSMDVLFSCSYDN
SIKVWAEDGDDDWHCVQTLNEASNGHSSTVWALSFNASGDKMVTCSDDLTIKVWGTDSLH
AQSGDGVGPWKHLCTISGYHDRTIFSVHWSRDGVIATGAADNAIRLFVENDDDLVDGPMY
KLLSKKEKAHDMDVNSVQWSPSEKPLLASACDDGTIKIWDYAST
>Sgl80695 E3_adaptor/Cullin_RING/DCX/DWD 98.7 10.1
MEERDSSTATGGGGGGGGGANQLYPNFLLDKLLKKASVRQVSKNASPVEQFRRALLKGYE
VSVKEVDTLMSLLSEKKRKMEQEEAERNMQILLDFLHCLRKQKVEELTEIQTDLQYVKED
ISAVERHRVELYRAKDRYSVKLRMLGDDSAPKLWPSTADRSSGGVSSGSHSSLGGLAAGG
FQNKKMDGKAQGPHAPPRKDALGGLDSQHISQSGLAVMRKKRIHVQFNDLQECYLQKRRQ
LTGQPARQDERDSTFMQREGYSTGLAEFQSVLSTFTRYSRLRVIAELRHGDPFHSANIVS
SIEFDRDDELFATAGVSRRIKVFDFSSVVNEPAEAHCPVVEMSTLSKLSCLSWNKFTKNQ
IASSDYEGIVTVWDVTTRQSVMEYEEHEKRAWSVDFSCTEPSMLVSGSDDCKVKVWCTNQ
EASVLNIDMKANICCVKYNPGSNYHIAVGSADHHIHYYDLRNVSQPVHVFGGHKKAVSYV
KFLSTNELASASTDSTLRLWDVKDSLPVRTFKGHTNEKNFVGLSVNSEYIACGSETNEVF
AYHKEISRPVTCHKFGSPDLEDADEDAGAYFISAVCWKSDSPTLLTANSQGTIKVLVLAA
>Sgl80715 E3_adaptor/Cullin_RING/DCX/DWD 120.2 19.7
MPVFKTPFNGYSVKFSPFYENRIAVATSQNFGILGNGRLHILDLTPPSPSSSLSELTFFD
TADGIYDVAWSESHDNLLVSAIADGSLKLYDLSLPPPQNPTRSLAEHTREVHSVDWNPTR
RDSFISGAWDDTIKLWTVDRQTSVRTFKEHVYCVYAAVWNPRHSDVFASASGDCTVRVWD
VREPGSTMIIPGHEHEILSCDWNKYDECLLVTGSVDKTVRVWDVRSFRAPLTVLAGHGYA
VRKVKFSPHQRNVIMSCSYDMTVCMWDFMVEDSLIGKYDHHTEFAVGIDMSVLVEGLLAS
TGWDEKVYVWQHGTDPRAV
>Sgl80745 E3_adaptor/Cullin_RING/BCR/BTB 82.5 3.8
MSKPTPLITDLTDIDLDPEDFNSSLPIKKVPYGDAFEAARAGDVDRLRYLIESGINVNAR
DQWDSVALYYACLAGHLDAARMLLENGAICDEHTFDGDRCHYAALNLKVRKLLKAFEARP
PPLGPLQAALRETFLGCLANRAFLELSDCQPQFSGSSVLDGPDNSHFPPDVVFYVHGRPI
EAHRVILSARSPFFKKKFETDWKDRREVRFSREKLSYPALYSLLHFFYSDRLEVGVDDME
DLVRICKVCKCEALRSVIEKELLHQIFTEFKALRDIDSSQRRFILQGLSLPEEDRLPAAL
HNILHFSLANSSMKQNSDDVADNLAASVGRLQIQEHVNDLADICVRVDGRVFRCHQVVLA
SRSEYFKTRIFRMDDFLEVNNDLLVHTLPCLEEHDLSQEAFEKMIEYMYTDSLKDVEPQQ
AEELFDAASRYLLFPLKRAVADALLPHLETASPSELCHWLLLSDMYGVLKIREYCLDVMA
CNFETFVDTQVFRAMLLTLPPPSGDSSLRTTAPSAPGAGGHINQGNILDDLREKWLEVEA
GDLDERDESALLFDNRLEMLMQIAKQEQEQEKPDSIDEVVTM
>Sgl80761 E3_adaptor/Cullin_RING/DCX/DWD 21.2 1.0
MYLYSLTLQKPTGIVSAINGNFSGTTKQELVVARGKVLDLISPDENGKLQTLTSVEIFGE
IRSLSQFRLTGSSKDYIVVGSDSGRIIILEYNKLTNSFDKIHQETFGKSGCRRIVPGQYL
AADPKGRAVMVAACEKQKLVYVLNRDSSSRLTISSPLEAHKSHTITYSICGVDCGFDNPV
FAAIEVGYTEFDHDSSGVSVAQAQKHLTFYELDLGLNHVSRKWSEPIDNGANMVVTVPGG
GDGPSGVLVCAENFVIYKNQGHPDVRALIPRREDLPAERGVIIVSVARHKSLSFILVQTE
YGDIFKVTLEHGKDSKEGVAELRIKYFDTIPVTCSMCVLKPGYLFAASEFGDHALYQFQG
TGDEPDVESSSVNMMELETDEGFKPVFFKPRKLRNLIRVDKVQSLMPIIDMKVFNLFEEE
TPQIFALCGQGPRSSLRILRPGLGVSEMATSSLPGVPNGVWTVKKNVKDEFDAYIVVSFA
SATLVLSIGETVEEVSDSGFLDTTASLAVSLIGDDSLMQVHPSGIRHIREDGRINEWRTP
GKKVITKVGYNRVQVVVALSGGEIFYFEVDMTGQLMEVEKREMPGDIACLDIASVPDGRK
RARFLAVGSYDNCIRILSLDPDDCLQVLSLQSVYSPPESLLFLEIQASTGGEGGADHPVS
LFLNAGLQNGVLFRTVVDMVTGQLSDSRSRFLGLKAPKLFSVNVRGRRAMLCLSSRTWLG
YMYQGNFFLTPLTCGILEFAATFSSDNCAEGIVAVAAEALKVFTIDKLGETFDQTVLPLR
YTPRRFVLQPKRKLLVIIESDQRAFKAEEREAAQNECFQVGQDDNGNLHMEDVDDNELSD
EQYGYPKAEAQHWVSCIRVLDPRTGETISCLELEDNEAAVSICNVNFSDKECGTLLAVGT
AKSLQFFPKKSFDAAYIHIYRLVDGGKLELLHKTPVDGVPLALSQFQGRLLAGIGTVLRL
FDLGKKRLLRKCENRLFPSTIISLHTYRDRIYVGDIQESFHYCKYRRDENQLYIFADDLY
PRWLTASQHVDFDTMAGADKFGNVFFVRLPQDVSDDIEEDPTGGKIKWEHGKLNGAPNKV
EEIVQFHVGDIVSSLQKASLTPGGVECILYGTVMGSLGAFLPFSSRDDVDFFSHLEMHMR
QESPPLCGRDHMAYRSAYFPVKDVIDGDLCEQFPTLPVELQKKIAEELDRSPAEILKKLE
EIRGVPGILLRVFGWHWQEVTIRVKTRSLKMSLNHYTKRILKSLDLQTR
>Sgl80773 E3_adaptor/Cullin_RING/SCF/F-box 21.7 0.0
MEGRRKRVRKTATRLNHIHTHIKPQPPISSSSSDSKVPKQASSSNKLKMLNSKSSSSEEE
EEEEEEEVEVLEASDLPCSILIDILGRLPLKTLIDCRYVCKSWRSLLTESYFYRLYSHHN
PTTLIIQIKGNSLTTLKEMCLIHHQGHSAGSLVRKMRLTTTHSKPVQGVDQNLRYQLGNG
CNGLICLRDTRTREPSLVWNPIMGQFVVLPKPVTPTNEKVVAGFGFCGRTNRYKVVRIFR
GVNDPPEKRRAEVYDLGVGYKWREIGDVPFLIPSRIPGFFTNNSLHWILDCPNNNTDDNN
LIDSNNKLNMELVCGFDFLEEKFKAIVPPPIFSDNENKYHWSNLGIIGDCLSICAIDAKL
FRPDVQVWVMEEYGVSESWALRLSIRDLTVDWWDPYKWIQVTSCLRNGEIMMLCAHCYVL
AYNVQERRFRSVGVLDFPAIAHVPSLISLEDVLSDNLGTGSLNVHYL
>Sgl80793 E2/UEV 225.8 0.0
MTIGSGGSSVVVPRNFRLLEELERGEKGIGDGSVSYGMDDSDDIYMRSWTGTIIGPHNSV
HEGRIYPLKLFCDKDYPEKPPTVRFHTRINMTCVNPETGVVEPKKFGMLANWQREYTMED
ILTQLRKEMAAPHNRKLVQPPEGSYF
>Sgl80845 E3_adaptor/Cullin_RING/DCX/DWD 26.4 3.2
MWRKEEGVLKKVCTTWRAVSRSELLWQTLVRIVWNTTTLLHATWRDHFIYLHRTSRNFQV
RRCLYATLQSLDYPLVPAPGGGDEGGGGGDDQLPILCLRLALAHDHMAAGFSDGSLRLFH
LPSRLHVRTVRPLLRDRLGLFSRAVSGIVLQPRDDRLVFASLDGDIHVVSPLIGPTPARR
TYLGDVVNDGALVDFTGCGRFWVGLYAGVPGRTFRVWSAESEELLFMGGSLTDPESVMGW
HMLTELRPTDFIGRIRVAPHDLAVGATSLRALVLDLDEPIVVVGEQTSRRGIIVGSVDAN
DEMFVMADTRGVASVRYLRTLEELCRFSVSAALRDGGGPISLRGLLGCINTMYVVMWIGR
TVRVWDAGHGEYLYSLREGVDDATALAASNQYVVAASSDTTIHMWDFGAQFN
>Sgl80846 E3_adaptor/Cullin_RING/SCF/F-box 19.8 0.0
MFPQQQQHNVDDDHQSSLIMLPEKKIKSLSLSLSLSSSFCINDQPDILVEVLKRLDGRSL
GVASCVCKLWHSISKSDDSVWEYVCFRHVLSPPPPTVRPLVRALGGYKRLYMVCVKPALR
RVNHTNTNKFSISRKVWTRQGAQLLLSLFCVDYYEKLGPNNNNSNSNNNSGTPSSLMFLC
KPVNV
>Sgl80852 E3_adaptor/Cullin_RING/SCF/F-box 13.3 0.0
MEPMEVTLPEEVLILIMIKLPVKSILRFRSVSKHWYDLLGSFEFINSHLHRNQTLISSHS
YALFKKILVFPQSEYFTLHTDNEQFHEIEDCKFPFTNFSMVGCAKGLVCIHHSDSIMLWN
PYIRRALVLSHSVEPPSISSYRVKMNIVAKRTFDWCFGIGYDVVSDDIKVVRISYFIFRS
NDDDDDDATPPHAFGHYFSVFSLRSKLWKRYASCGSIHSNAHSFNVGGFVYRMQPVGPGV
GRLAITCFDLSAEVFTRIDIPKLGSNDPNVPLNDIDVRMINYHESLGLIHEWKHMNYDIW
ARRGEGLAKSWTKLFRVRLGGVMAWQRLVGFTKKG
>Sgl80862 E3_adaptor/Cullin_RING/SCF/F-box 17.6 0.1
MSTELLHDDLLAEILIRLPAESLLKIKCVCKSWYSLISSSRFILAHVCHNRSKNPRILLR
SFNKADKKVSYKLCHDNECLDDIMTIDPPFMRQRNDFLRMVGCINGLVCLSDDTVEVTDS
VILWNPVIRRFLPLPKLELNVDSNDLGRSVFGFGYDSTNNDYKVIKIVYRKNPDFEARQV
EASIAIYRLSSCCWEVNGSASVPLLDSRQAYVNGVIHWLAYNKLVVGFAVESEAFSDTML
PETLQNANISDLAIASWCDLLSVFQNGFWSGRLCLWVMKDYGVAQSWVKQFVIESYVMVR
SLRRNGCVILENIGGKLVLYNSKTNQFEEFKIHVEGSIRGFHMKSYVESLVLSDRLDAKS
IP
>Sgl80890 E3_activity/RING/RING 30 6.1
MEFGSGNFGCKHYRRRCKIRAPCCNEIFDCRHCHNEAKDSFQVDAVSRHDIPRHEITKVI
CSMCDVEQDVQQNCIQCGVFMGKYFCSICNFFDDDVSKLQYHCDECGICRTGGKENFFHC
SSCGCCYPNTMKGTHRCMEKALHHNCPVCCEYLFDTTNEVSVLSCGHTMHLECAKQMAQH
YQYACPICLKSMCDMSTVWRKLDEEVASTLLPEECQRMVRILCNDCEANSNVQYHDVPPL
PKKKSIRSNVAKKVCEAAAEGPKRAKDESKSEKARTENPNSNEASSLRNKHQFYHNHQS
>Sgl80924 E3_activity/RING/RING 17.1 0.1
MEPDSPPPILSPRLRILQRLATNGIPEEYLEDLQPGLVRFMKNNKHRTSEVISAVLPTDI
DIAEVASEGKMRSSKASDHPNLKDVYRESLLWIKWLMFEDEPSTALTNLANMSVGQRGVC
GAIWGRNDIAFRCRTCEHDPTCAICVPCFKNGNHKNHDYSIIYTGGGCCDCGDETAWKRE
GFCSKHKGAEQIQPLPDEIANSIGPVLDHLFSYWKDTFLVAENILKGDLTNEYDIDPRKV
ANEFSYVVVEMLLNFCNHSESVLSFVSKKLIGTVDFLPLVVRSERFLITDVTKKLHELLL
KLLGEPIFKYEFAKVFIDYYPVPVAEALRTSSDNVLRKYPLLQMFSVQILTVPTLTPRLV
KERNLLAVLLECLGEIMFSCCGEDGKFQVNKWCGLFDTCHRVMEDVKFVLSHSVVAEYVT
HERLDIVKVWLQILSLVQGLNPLKRETSIHVEEESDNAHLPFIMCNSIATIQLLLVKGAF
SVAESKVMDEDGSFEREKNNTDDGYVQRHAKVGRLSEESSICSSAVQNSISESSSQKLHG
NNDLSVPSSALQLIFESTKAIDSWLVGSNVVTSENACSKLSALKETLLKVKKRMNFLGSS
YGYAEINDHDHGSGALQVQSATNSCPMDMDKDSSPMETELSDEKDALFLLSLSDWPDIDY
DVSLQEISVHMPLHGLLSLNLKEALRHYCGEPGLTEKGDFINLNPLSHDHLDFFRKVLRG
CQPYGFSSFMMEHPLQSRVFCSQVRAGMWRKNGDAAILCFNWYRSIRWSDHELELDLFLL
QLCAAYAPADLYVRRILERFQLSNYLALDLKRSSEYEPVLMQELLTLIIQIVKERRFCGL
TASQSLQRELVGKLATGDATHSELVKSLPKDLSKLDQQQEVLDRIAQYSNPSGMNQGKYS
LQMQYWKELDLYHPCWNPRDLQVAEERYSRFCGVSALNTQLPKWLSIYQPLIGIARVATC
KTTLQIIRAVLFYAVFTDRSTESRAPDGVLIPALHLLALALDIFSLERKSGHDGDCIMLV
TVATEEIEVGLNIQSGHQCLLSLLVLLMRMHKKGNTGSSMEAGSFNISSLVEILLKKFGE
LDSHCMTKLQQLAPEIVNYKIDETANSSSASDSEKRKIKARERQAAVLAKMKAEQSKFLA
SLKSSADEGSDNPGSQKEKHASNVPQDSEPHVCCLCHDPNSSNPVSFLILLQKSRIVNFV
DRGPPAWDQGMQSDGLESSVSAYEGIDSSIRGANALSAESSSSSEFVQSVEGAIDEFATQ
AHPEELNAFIDYLKSQYPELRKFNVRSKLAEKKAKSARSLELLEQDLFLSIHKDIRSIDG
FDFLRKDEGENAARSVLLGKYVAALAKASKGPSQDNNLHRVESAVQISSSKRFGPSDCDG
IHVSSCGHAVHQGCLDRYLLSLKER
>Sgl80928 E3_adaptor/Cullin_RING/DCX/DWD 114.4 44.1
MAAMAMDTDENVKRLQIRFITQLEDQFKVPTNAIAVPSNLTRFGLSSIVNNLLKAVDSDW
EPEPFDFLINGELVRLSLEEFLLAKGISAERILEIEYIKAVVPRKHEEPRLHDDWVSSID
GSNPGFVVTGCYDGFGRVWKGAETCTQMLRGHSGALTSLCMIDAEGSDSGNKLHVATASK
DRTVRLWQFDAEDSRNNPTSITAYKVLRGHTASVECVSSQKSGKMVCSGSWDSTINLWQT
GLSDGDADFASVKKRKKSGVVSEAQAEGEAVSTLAGHTNCVSSILWAQDETIYSASWDHS
IRIWDVETGNATWSMFCGKPLNCMDVGGESSALVSAGGSDGTLRVWDPRRPGSLAPVYQF
SSHTNWISACKWHEKSWFHLVSSSYDGKVMLWDLRTAWPLSIIDSHSDKVLCVDWWKDNC
VVSGGADSKMCTATGISVK
>Sgl80975 E3_activity/RING/RING 30.2 7.2
MFSRRMLDTPFFDHKQAATPPPPPNDQLYPSSSSNHRSSFDANVVMIFSVLLCLLIFSIC
VNCFIRCVLKCLIMVTQERRRRNHHQQKLVSCGVDKRALKTFPVMKYSKEVKIQGLSTEC
VICLSVFRSGEKIRILPKCTHGFHVKCIDKWLTSHSSCPTCRQSMVDTCQKIIGCHDDQC
RQFTSSSSTAEMVSISIVPLEREDVISRY
>Sgl80981 E3_adaptor/Cullin_RING/SCF/F-box 15.2 0.1
MTAVVLKVVFPLLDGVDLASCMVVCKQWRNVAQDDYLWKCLCARRWPSLCKRPLQSTVSF
YKLYGTFYKRQRRRVLLPPRLSFNDLDFYIDVWTESQLIFSEVVPGPLLHTGINILPTVI
SDTLRCHLESPEYKMVLPVEPRFSVPVGQKTRVSVLVGRKDLNKFACIINKAMFDYVDRT
SFRALAFDYLDFSPAHPFISGIRAWISLLFTDDKNDEVADVFGIEMDFCDAASNEREVLW
LLDMLDWQ
>Sgl80988 E3_activity/RING/RING 25.5 7.7
MVSKWRKAKLAFGCIQIPRTNDDEIPSSSPISTATPSSVVSNNNNGHNPRRISDASAVTP
PTPSSSGGLRLSKSFPKSSKKTCAICLSTVISGQGHAIFTAECSHTFHFNCITSNVKHGN
HICPVCRAKWTEIPIQGQSSEVLRGKLRANSVNWNRDNPLVAALQQLPLPQPDYNHNVTP
TYRIGEPSVFDDDDLIDEQQISREHSADNASDDHSDRRIEIRTCPEVSSVSKSSSYENFT
VLVHLKAPIARTSNLDSNSPSGSQNSRAPVDLVTILDVSGSMAGTKLALLKRAMGFVIQH
LGPHDRLSVIVFSSSARRLFHLRRMTDSGRHQSLQAVNSLSANGGTNIAEGLKKGAKVML
ERKCKNPVSSIILLSDGQDTYTINGLAGAQSRTDYKSLLPSSIQQNTGTSSQIPVHTFGF
GVDHDSASMHSISENSGGTFSFIEDEGVIQDAFAQCMGGLLSVVVQELKLELQCVDPSLQ
LDSIKAGSYHARLMPDAKIGYINVGDLYAEEERDFLVTMNIPQTSCVSEMSLMKVNCTYK
DPITKELTTLGEIEVVKINRPDKAEDVVVSTEVDKQRNRLKAADAMSEARFAAELGNLVG
AVSILESCRQTLSESVSAQDPLCVGLLNDLKEMQDRMSSQQVYEDSGRAYVLSGLSSHSW
QRATARGDTTTILSQSYQTSVMTDMISRSQTMVLGRAPSPNVRPPRSLSGRPRPR
>Sgl81064 E3_adaptor/Cullin_RING/DCX/DWD 60.6 6.6
MNNNSSNTTTTINGGNSTPLNPLKNYFKTPEGRYNLHSEKSHPSTIVHFAHGKSVTQVSV
ANLKEKSASTTPTSSSGYSATGSVRSAAAKLLGTSNGGRALSFVGVNGTNKAVAATTKTT
SIGSNSNGVNLPIANFDGKGMYIIYNVGDNLYIGDLNTQEKDPIKWMNFANSIPVCHAFN
PDAKDGHDLLIGMNSGEVYTASLRQQLQDIGKKLVGAQYYNKDGSINSSRCTSLAWVPQG
NGAFVVAHADGNFYVYEKGKDAPVDSSFSLIKDPAQFSVSHAKSNKSNPVARWHICQGSI
NRIVFSPDGSHLAVVGRDGFLRVYDFQKEQLVCGGKSYYGAILCCAWSMDGKYILTGGED
DLVQVWSMEDRKVIAWGEGHNSWVSGVAFDPYWSPPSSDSTGENVMYRFGSVGQDTQLLL
WDFSMDELVVPLRRCPPGGSPTYSAGSQSSQWDSAVPLGSLQPAPCTRDIPKLSPLVAHR
VYSDPLSDLIFTEHYILTACREGHVKVWMRPGSSESVSTDSETVSNSKEKPTIPNPSGVN
GK
>Sgl81098 E3_adaptor/Cullin_RING/DCX/DWD 88.9 14.9
MYPRIAFREIALPRKKSKENLDRFIPNRSAMDFDYAHYMLTEGRKGKENPAASSPSKEAY
QKQLREVFNMNRPRILAFKNKPPTPVEFMPQDYATVQPSKPVKPRRRIPQTSERTLDAPD
LLDDYYLNLLDWGSNNVLAIALGTTVYLWDASSSSTSELVTVDDDKGPVTSVNWAPDGRH
IAVGLNNSEVQLWDSAANRKLRTLKGGHRARIGSLAWNNHILTTGSMDRKIMNNDVRIRD
HIVETYRGHQQEVCGLKWSASGQQLASGGNDNILHIWDRSLASSNSATQWLHRLEDHTAA
VKALAWCPFQGNLLASGGGGADRCIKFWNTHTGACLNSVDTGSQVCSLLWSQNERELLSS
HGFTQNQLTLWKYPSMVKMAELTGHTSRVLFMVQSPDGCTVASAAGDETLRFWNVFGTPE
VAKPAPKAAPEPFAHVNRIR
>Sgl81099 E3_adaptor/Cullin_RING/SCF/F-box 15.7 0.0
MAMKKAKLSIIDDDKPSKNCEDDVVLPQTLASVDHLIMKEILPRLPVKSLIRFKLVCKKW
KSTISSLQFAKLHLNFSSSNRRHFIVFPTTDKFCGNEKCTSFCLLPYRESSNVKDLVKLS
GGVKDVHWYNIVDSSNGVVCLYQRNDFECEKGCFFTLWNPATGEDRDITSPNGVHASEAY
GFGYVESIDDYIIVASFGSGTFEYNKFRGLYVYSVRAGKWKRVFGSYAYLRMNPWCWKWK
TVRSKSDDEFLAKRLRGEAVFVGDTMYWIRGKVIGFDVVSNELEKYPRLDCQGEYRSLKL
FQVKGCLSLKGERENGVSDFWILKNSDDWSSWQKFFSADFTNISLITLSETGKCLVRRSD
EFKLVDPCKEGLDCYQGNHDNFGRMVITRDHVESLFSPFGITETDDEEDTGEKEDIDEEV
DTNKKEHTDEEEDSTGIFNHLTTNNMSSENKWLSFPPKVDNNSGTEKNDFEGDSDDYNDD
DEAGYDYNEDLDDDSESYSEWETSDDERDYDGIYNNDDDDYVDHDDDDY
>Sgl81100 E3_adaptor/Cullin_RING/SCF/F-box 14.7 0.0
MAMKKAKLSIIDDDKPSKNCDDDVVSPQTLALVDHLIMEEILPRLPVKSLIRFKLVCKEW
KSTISTLQFAKSQLNFSSSNRRHFIVFPDNAEFCGNENCGYFFLLPYSECSNAKDLVKLS
GGFKDVDWYDIVDSCNGVVCLYQQYDGRFERGCFFTLWNPATREDRDITCPKGIHVSEAY
GFSYVSSLDDYIVVASFGSGTSNYNKFRGLYMFSVREGKWERVFGSYALLRMAPWCWKWK
TVRAKSDEELIAQRLLGEALLVGDTMYWIQSSGKITGFNVVSNELKEYPRLDYVSEYRSL
KLFQVNGCLSLQGERGNGVSDFWILKNTDDWSSWQKYFSADLTNISLITLSETGKCLVRQ
SEEFKLVDPCMEGLKSCQGNGVNFSHMVITRDHVESLFSPFGTTETDEEVNTHEKEDTAE
EDNNGISIHVTTNNMLLENRLSFPPKVANISNTEKNDLCGDSNDSVNADEEDDGESENDY
EDLDGDFEAYGEWETSDDECDYDSDYDSDDDHDDDDY
>Sgl81114 E3_activity/RING/RING 10.8 4.0
MSIDHMLFWSTLGHPLFPVKLIPNNAPTDGTNPVQIVEKTFHLSRTDRDLLSKPEYAVQA
WCMLLNDKVCFRMQWPQYADLQINGFPVRALSRPGSQLLGANGRDDGPNISQCTREGINK
IFLSGCDARIFCLGVRLVKRRPLQQILSMIPKELDGEIFEDALARVRRCIGGGEAENADS
DSDLEVVTESITVNLRCPVSNLIEEDLNCLTYKLPHFCLVKNYACQNGCLLPLYKFVTGR
SYMLGYLEIEMSGSRMKTAGRFRPCAHMGCFDLETFVEMQQRSRKWQCPICLKNYSLESI
IIDPYFNRIANMMQSCGEDTTEIEVKPDGSWRVKGENECKDLRQWHLPDGSICLPDEGEL
KHKPEASKPVKPEGTGLKLGIRKNSNGLWEVSKHGDMNTFSSSDRIPENLENGGLKVIPM
SSSATISGRDGEDPSVNQDATVNFDLSVTNGVELDSISLNLDPTFGLTTQNALAAAKDAN
VIVLSDSDSENGMMVHGIVHNNGLMDNGVNYTVNSHGITGSYQTDAGLGVGGSSCLDLFN
PADDEFGLPIWPGMPSTTQGASSFQLFGSDGDGSDTLGNPHLSAVNCSTSMNGYMLAPET
AMNPAAFVPDSAVNHPSHDLNDGLVDNPLAFGGEDPSLQIFLPTRPSDTCGSSDVRNHQD
MANGLSNEDWISLRLGDGGGRNPGDSVAVNGLHIGQQPHSRDGNMDSLAETAPFLLGSNG
NKSEKTRERSDSPFPYPRMKRRLYLSIDSESDYPVHRNLEGCLR
>Sgl81137 ULD/UDP/UFD/UBX 38.5 0.0
MASEHENQNNNNMTSINTFMEITSSTQQEAQFFLESHNFDVDAAVSTFFESNSAPPLPPP
HPQPQPSSAIDEDADADADAEFIPQPSSSPSGSPSPSPSRSRSHSPPSGVRSQYSLRSKR
KSNKNSGKGEGRSSNSRRSGRVGGVRTLADLKNKKSTSDDSGSDSDGDRPSQYFTGGQKS
GMVVQDPSNDNHVEAIMDQAIRMGATEGPVDVHQPSSSSRSFTGMARLLSGETISSSPQE
QAPPETVTHTITLWRNGFTVDDGPLRRFDAQENASFLESITKSECPNELAPADNKTAVQV
SLVRKNESFAEPKKQKNAFTGVGRTLGTSSSTSSDPSTVAPAPMSAPPPVMGLVVDDKLP
STSIQLRLADGTRMVSRFNYHHTIRDIQAFIDASRPTRTGSYTLQIMGFPPKQLTDLDQT
VGQAGLANSVVIQKF
>Sgl81210 E3_activity/RING/RING 24 13.1
MINENTISYENNLLLASILCLLLVILFVLLLHIYARWLLAEGHLCGTTLASIFSPTTRLR
RSHTSTSSTTYTYDITSISSCSYHTKGLDQKIIGSIPTFVYIPPSSSSEGVAALECAICL
SVFEEKEVGRSLPRCLHAFHVECIDMWLCCHSTCPICRAHVVVVDQVVDEDRVCGGDDVN
QTVVIREQNHHDRRLSTSVDQIVVQIIDDDQNVASSECSTLDYCSSTRILSSNNRV
>Sgl81366 UBD/UBC-like/UBD_UBC 103.2 0.0
MSCISRNYELPYYLSWSYLGIPYLQGPSETPYEGGVFQLAFAVPEQYPLQPPQVRFLTKI
FHPNVHFKVRALRLICLDILKNAWSPAWTLQSVCRAIIALMVHPEPDSPLNCDSDNLLRS
GDLRGFQSMAKMYTRLAAMPKKG
>Sgl81425 E2/UBC 67 0.0
MVELPDAYPYKSPSIGFVNKIFHPNVDEMSASVCLYVINQTWSPMFDLVNVFDVFLPQLL
LYPNSSDPLNGEAAALMMRGKVVYEQRVKVNGQRTKSNLWLEVSVLGGLKLKEKDSRNLN
SLINPSLLLKLEAISHAAELFRRRLEDYDCGDPIPVNILDSWSVRQVPILLFHCDPEERN
SCDSFCEGGLMNNAFEYILKSGGIQREEDYPYPGANGTCHFDKSKVAAKVGSGQLQLHAD
IHWWSLLPIHMFEEFGPWIAIGWLWIFRLIRLNTASRCISCRVVEL
>Sgl81444 E3_adaptor/Cullin_RING/DCX/DWD 53.1 6.1
MSPLSLTPEKNEIIGGNACTISSCGNFAVLGTEGGWIERFNLQSGMSRGSYLDKSERKSC
GHNGEVVGVACDSTNTLMISAGYHGDLKVWNFRERELKSRWDVGCPVVKIVFHRPNGLLA
TVSDDLIIRIYDVVARKMVRKFEGHNDRITDVCFSEDGKWLLSSSMDGTLRIWDIILARQ
IDAIQVDVAITAVSLSPNMDVLATTHVNQNGVYLWVNRLSYADSYASGKDILLVNLPSIS
AGENNEMIDAEEGNTNHLHVKEAARVPTFDQRMPDLVTLSLLPKTQWQSLINLDIIKIRN
KPIEPPKKPEKAPFFLPSMPSLSGDIMFKPSEVTYEELKDGDAEQKSDYVTDSPLSPFLQ
ALQYAVDSKNFSSFTDYLKGLSPSSLDMELRMFQIIDDDELLERSRQAVLSLDMLLDYFI
YEISCRHNFEFVQAVVRLFLKIHGETVRCRSQLQEKAQKLFETQCAVWQRVDSLFQSARC
MIAFLGDSQF
>Sgl81445 E3_adaptor/Cullin_RING/DCX/DWD 63.2 4.0
MGIFEPFRAIGYITSSVPFSVQKLGTETFVTVSVGKAWQIYNCAKLNLVLVGPQLPKKIR
ALASYRDYTFAAYGNKIAVFKRAHQVATWNYHSAKVNLLYLFGDHILSVDVKHHLCLWAF
KEINQKFEPISHIVLEGTPTCIVHPDTYLNKVILGSQEGNLQLWNVNTKKKLYDFNGWNS
PISCCVSSPALDVVAVGCADGKIHVHNLRYDEELVTFTHSMRGAVTALSFSTDGQPLLAS
GGTFGVISIWNLEKRRLQSVIKEAHDNAIISLHFFANEPVLMSSSVDNSIKMWIFDTSDG
EPRLLRFRNGHSAPPLCIRFYANGRHILSAGQDRAFRLFSVVQDQQSRELSQCHVSRRAK
KLRVKEEEIKLKPVVAFDCAEIRERDWCNVVTCHMDTSEAYVWRLQNFVLGEHILSPSDE
NRLQ
>Sgl81626 E3_activity/RING/RING 29.7 8.4
MQLRSNRILPEPSVPSDNVENDVGNAMAELNEALGVDFVMEDNDSEIDDEIVKETKKVGR
KRKKSSKKKGKIKKQSNDGVMDPAEREASRFEGISGFEFVDPVEMLKKVRKKKNGELKPT
LMWEVWEAEHSKWIDKYMTDDIDLDQQNIVMDEMVDEPSELATELLRFQKEWLAWALKQE
SSESRGGILADEMGMGKTVQAIALVLAKREIRRAVNGGDEFSSPSSSSMLPKLNGTLVIC
PASALSQWKREIERFTRVGSTKVLCYQGPKRVRSSLRFSNHDIVITTYNTIEADYRKVLP
PKIKCEWCGNCYSERRMAVHLKYYCGPNAKKTEKQSKQNKKNKKLNLKVLKTFSKDNVEV
NDDKQDAAQYKSEKVNNNNEGSEIQFEQEDLDDIEENVRKSVLHSVKWERVILDEAHCIK
DRRSNTARAVLALQSSYKWALSGTPLQNRVGELYSLIRFLQIYPYSYYMCKDCDCKTLDY
SFSLECKSCTHSSVRHFCWWNKNIATPIQLHGNYWRQRAMFLLKHRILKKILLRRTKSGR
ASDLALPSRAVLLRRDSLDIKEADYYQSLYNDSQAQFNTYVIEGTVMNNYAHIFDLLTRL
RQAADHPYLVVYSRSNTAKNVTGVETENGDQVCGICHDPVEDPTVTSCGHIFCRVCLIDF
SSSVGQPTCPSCSKPLTADFTSNSGTGERRSKTAVNGFKSSSIMNRIQLHDFQTSTKIDA
LREEIRLMIERDGSAKGIVFSQFTSFLDLIMYSLNKSGITCVLLDGSMTIAARDNAIRRF
HEEVDCRIFLISLKAGGVALNLTVASHVFLMDPWWNPAVERQAMDRIHRIGQYKPIRIVR
FIIENTVEERILKLQEKKELVFEGTVGGSSDALAKLTEADLRFLFVT
>Sgl82354 E3_adaptor/Cullin_RING/DCX/DWD 92.5 13.0
MRVKVISRPTDEFTRERSQDLQRVFRNYDPSLRPQEKAVEYVRALNAAKLDKVFARPFIG
AMDGHIDAVSCMAKNPSDLKAIFSGSMDGDIRLWDIASRRTVSRFLGHQGAIKGLATSTD
GRILVSCGLDCTVRLWNVPDPSVMHSDESSEESPTPFGVYTGQNAYKAVDHQWGGNLFAT
AGARLDVWDHNRSQPVNSFEWGVDTVVSVRFNPGEPSLLATSGSDRSIAIYDLRLSTPAR
KIIMQTKTNSICWNPMEPLNFTAANEDCNCYSFDTRKLAEAKCVHQDHVSAVMDIDYSPT
GREFVTGSYDRTVRIFSYNGGHSREIYHTKRMQRVFCVKFTCDASYVISGSDDTNLRLWK
ARASEQLGVLLPREQKKHEYNAAVKNRYKFLPEVKRIIRHKHLPKAVYNAQNLRRTMTET
ERRKDERRKAHSGPSSVQKKPLRSRKIIKEIE
>Sgl82391 UBD/UBC-like/UBD_UBC 110.2 0.0
MKLCPREVEKLALHNAGFLAQKRLASGLRLNYTEAVALIATQGPSETPYDGGVFQLAFAV
PEQYPLQPPQVRFLTKIFHPNVHFKTGEVCLDILKNAWSPAWTLQSVCRAIIAFMAHPEP
DSPLNCDSGNLLRSGDLRGFQSMAKMYTRLAAMPKKG
>Sgl82410 E3_activity/RING/RING 19.6 7.8
MPSENHSPELQNDEAPSRFDPKLRRCDALFVQQKPVEEEEEDDDDAVVNNQQQLFQPQLE
DDVVSNDEDLDSFEEEENPTEFVNVDLHATRKEVQCPICLGIIKKTRTVMECLHRFCREC
IDKSMRMGLGIYCFYLCFLALEIVSFLNNECPACRTHCASRRSLRDDQRFDQLIAVLYPD
IRKFEEEEVAFYDEDEARNKQIQESITQVLIKQSEALGKKRSSNKDAAGPSVTRSQRKQK
NSHSRKRRRRKNSSIEYQDSDNSDDVIDSDKQFSTNEHHPEVKLKRARSRVSIEVSQSPS
ATNLSRGSSDNNVEQNKEERNISPSLTIGKERLSWGRGGARSNTRHGNVNNGSTSRRRLR
LSKLVDFVNNLEEVDDESALETPMKDENAQHISRQDQNDSLAHQSLLQPSSCSNNKQTQV
ADLLQDTLHRLDREKTLPGAIASCISSGEQLVLAYSHTKEAM
>Sgl82428 E3_activity/RING/RING 23.1 3.8
MGFCRRGERVLGFQWRKKLGFFSKVILGLLIFFVLFEPATSLRPLREKARSWGDEWLFVK
KEDSNMASFSSWNISGTYRGNWKFLDSANISSRFPDFQRSDGNSVIELMSTPTKITGVHY
VQGVIIFHDAFDDDHEGGGAQIRVEGVYIWPFRQLRMVANSGKDSEFSPEEDYLLSNPYH
LLGVFSSQVFQDSTRDKIWRRKKSQVQDIEKHCNIEIAAQVSRVASLQNDGDHDRYHLEG
LMESPSADEDGDCFSPLSLNGTSVNIEVYYNKAVNYTLMVTFVSFLQVLLLIRQMEHSNT
QSGAAKVSILMIGQQAIMDAYLCLLHLTAGILVESLFNAFATAAFFKFVVFSIFEMRYLL
AIWKASRPANSGEGWEAMRRELSLLYSRFYGLLLGGILIMYEFHNFLRPILLLMYSFWIP
QIITNVVRDSRKPLHPHYILGMTLTRLAIPLYIFGCPNNFMRIGPDKKWCICLCTFLGLQ
SLVLLLQHYLGSRCFIPRQILPEKYSYYRKFDQDGNHMTDCVICMTSIDLCARSNNDCMV
TPCDHFFHSGCLQRTIPRILPRVFIKQKKDDIHCSS
>Sgl82474 E2/UBC 95.6 0.0
MDMEVNYCNESLPSDSVIAKKLKQEKEVSTSDLMESTAVIDSVDNANAGKTLTSGSNNSV
DQNGSASDLSFQDDAIEDDEDYVDDDDMVSDYDDNNEFFYDNDDDDDDYLKLQAQFDNVD
LPPGVEASVPWLNDPSPSEKPVAVGTSTSSAQEEKVCASSSSSKAALSSKVKKEEEMDDV
LRKLMYFKQFDTVADCSDHHYLEMKSSQPSKTWIKKIQDEWKILEQNLPDTIFVRVYESR
MDLLRAIIVGPSGTPYHDGLFVFDAVFPSSYPQEPPMVHYYSSGFRLNPNLYECGKVCLS
LLNTWTGGREEMWVPNKSTMLQVLVSIQALILNAEPFFNEPGFERTYKGQEGKRKSQVYS
EDIFIKSLKKMMYTLRNPPQHFEDLVAGHFRVRALDIMTACNAYVEGAEIGCNVKEWLEK
GDAAPKTGSTNFKAEVAKTMKPLNKYFINNGSKDTEMFQS
>Sgl82503 E3_activity/RING/U-box 31.8 0.5
MEQCFEQPIARECCSGDDITKCKSPSAGVAGMVNNNSNSSGGFDCNICLDFVQDPVVTLC
GHLYCWPCIYKWMQSQITMFESSDQQPQCPVCKTQVSQSTLIPLYGRGQTSKPTTKFDVV
VPKRPNGPGCGVHTLVTATTSRSQQLHHDQQLHHRGYHRHQQQQVHPYYSVDDYQSPTLG
LAGTTTYNPMISMFGEMIYARIFGNSQTTLYSYPNTYSIAAASNARVRRHAMQVDRSLSR
VSFFLCCCIILCLLLF
>Sgl82652 E3_adaptor/Cullin_RING/DCX/DWD 41.6 6.6
MFLLFRDSDFPLPFAVDIISAIEFDKTGDHLATGDRGGRVVLFERTDTKDHGVNRRDLER
TDYPISRHPEFRYKTEFQSHEPEFDYLKSLEIEEKINKIRWCQTSNNALFLLSTNDKTIK
FWKVQEKKVKKITDLNVDPSKAAGNGSIVSSGVSSSSKPYLVNGGYPDKLPNSLNNESFS
PGGIASLRLPVVTSCESSLHARCRRVYAHAHDYHINSISNNSDGETFISADDLRVNLWNL
EISNQSFNIVDVKPQNMEDLTEVITSAEFHPSHCNTLAYSSSKGSIRLIDLRQSALCDSH
AKLFEEQEAPGSRSFFTEIIASISDIKFAKDGRYILSRDYMTLKLWDINMDAGPVATFQV
HEYLRPKLCDLYENDSIFDKFECCLSGDGQRVATGSYSNLFRVFGCAPGSTEATTLEASK
NPMRRQVQTPSRPSRSLSSITRVVRRGSESPGVDSNGNSFDFTTKLLHLAWHPSENSIAC
AAANSLYMYYA
>Sgl82762 E3_adaptor/Cullin_RING/SCF/F-box 22.8 0.1
MKKIKTNRSPIEEIPPEIMFDILSRLVTKTCLNCKLICKNWYQMIISQESGSILVGKKKR
TDFLLFDLDKSCKVDEDGSLIVSNNDAVFRFKSKLNLPIAIYQW
>Sgl82779 E3_activity/RING/RING 32.9 7.3
MVYTLQPNSDSSSVAATGGESSMVSDLLIVGPGALGRIVAQQWIQDHPGCQVYGKTVTTN
HHDELKSLGIIPLLKGTTLPRQFPYVIFCAPPSMTSDYAGDLSIYINSSMLHKHHQNLLK
AVAESNDESVVHPLPNLFRLLGITPFKKAEFTPDNLYTRKRPLNSLASVHAKNLKKLAAD
AKNPEAEEGVSDADVDSIVGVGDSSKLEEMDPPSTLLCDLRPYQKQALHWMVHLERGKTT
DEAANTLHPCWEGYRLADKRGLSVYLNSFSGEATVEFPSTLRMARGGILADSMGLGKTVM
TISLLLSNSERVIPSSQLTPVESAEQSKTAGSSPDPFMKASKPQGLDKLMRQDNILIDGG
SLIVCPMTLLSQWKGEIENHAQPGSLSVYVHYGQGRSRDPKVLAQYDVVLTTYGLLASEI
SSENSQGCAVLQSIRWLRVVLDEAHTIKSTKSQVSVAASALTAGCRWCLTGTPIQNKLED
IYSLLRFLKVEPWGNWAWWNKLVQKPFEEGDERGLKLVQSILRPIMLRRTKYTVDREGRP
ILVLPPANVQVVYCELTEAERDFYEALFKRSKVKFDRFVEQGRVMYNYASILELLLRLRQ
CCDHPYLVMSRGDTQDYADLDKLAKRFLRGGCGTADGEEKVAPSKAFIQEVVEELKKGEQ
GECPICLESFEDAVLTPCAHRLCRECLLASWRNSASGVCPVCRNTVNKKDLITAPTDSRF
QVDIEKNWVESTKVSSLLQELESLRSSGSKSIVFSQWTAFLDLLEIPFKRNNISFLRLDG
TLSQRQREKVLKEFSEENDVMVLLMSLKAGGVGINLTAASNAFVLDPWWNPAVEEQAVMR
IHRIGQTKTVSIKRFIIKGTVEERMEAVQARKQRMIAGALTDEEVRSARLEELKMLFT
>Sgl82787 E3_activity/RING/RING 32.6 7.3
MNSKIKDEVIETIRSVVGQNYTEMDIIRALHMANNDATGAINIIFDTPNFISQSRQNPRI
NSAQRVKVPTTNLITIEDEINEVRHPKDEKLGDMQMVEYGLQKRENEGLDSSLVPVSVSV
SLSEEWWFVGYGEILAMSTSKGRRIRMGDEVEFGFPLKNKLKSKVFGRGRPVAACSEIVR
FSTKSGGEIGRIPNEWSRCLMPLVKDNKIKVQGFCKYAPESLSIMDTIALNVSIYINSSM
LHKHHQNLLKAVAESNDESVVHPLPNLFRLLGITPFKKAEFTPDNLYTRKRPLNSLASVH
AKNLKKLAADAKNPEAEEGVSDADVDSIVGVGDSSKLEEMDPPSTLLCDLRPYQKQALHW
MVHLERGKTTDEAANTLHPCWEGYRLADKRGLSVYLNSFSGEATVEFPSTLRMARGGILA
DSMGLGKTVMTISLLLSNSERVIPSSQLTPVESAEQSKTADSSPDPFMKASKPQGLDKLM
RQDNILIDGGSLIVCPMTLLSQWKGEIENHAQPGSLSVYVHYGQGRSRDPKVLAQYDVVL
TTYGLLASEISSENSQGCAVLQSIRWLRVVLDEAHTIKSTKSQVSVAASALTAGCRWCLT
GTPIQNKLEDIYSLLRFLKVEPWGNWAWWNKLVQKPFEEGDERGLKLVQSILRPIMLRRT
KYTVDREGRPILVLPPANVQVVYCELTEAERDFYEALFKRSKVKFDRFVEQGRVMYNYAS
ILELLLRLRQCCDHPYLVMSRGDTQDYADLDKLAKRFLRGGCGTADGEEKVAPSKAFIQE
VVEELKKGEQGECPICLESFEDAVLTPCAHRLCRECLLASWRNSASGVCPVCRNTVNKKD
LITAPTDSRFQVDIEKNWVESTKVSSLLQELESLRSSGSKSIVFSQWTAFLDLLEIPFKR
NNISFLRLDGTLSQRQREKVLKEFSEENDVMVLLMSLKAGGVGINLTAASNAFVLDPWWN
PAVEEQAVMRIHRIGQTKTVSIKRFIIKGTVEERMEAVQARKQRMIAGALTDEEVRSARL
EELKMLFT
>Sgl82806 ULD/UDP/UBQ/UBQ_PIM 73 0.2
MHIFVKARNTITLEVESNDVINNIKAKIHDKEGTPVDQQRLIFSGKQLEDDRTLAEYNVE
KDSTLHLSLRLRGGGYGTLKCYPPNLLVLAQKYKQNKKVCRKCYARLPLRATNCRKKKCG
HSNELRLKKVFQAKGV
>Sgl82814 E3_adaptor/Cullin_RING/SCF/F-box 15.7 0.0
MAKEEAMGTDLPNDLIIEILLLVPAKSVASFKLVSKYWNSLISNYKFAKSHAHTIFKTTR
LIFRLINGGRYGSKKNATTTLFNEALHWITRDDFLLKFDLVEECFKGEAISKKTQIEKNY
MIIDKLIGVTEDGNLCVHTLYENDHMPSYISSPRYDYCVDSRISNKDRRSLFGNFYFSLE
GKYMVLQIECNGKAMVFGEYGDDFMKEMLIVDARQLPPLFIKVRNEFSAPNENRDTYIHT
LVDEVSYVQSRVSPFQK
>Sgl82824 E3_adaptor/Cullin_RING/DCX/DWD 60.1 16.2
MTVVSAHKFAQCITCHAWSPDHSMIAICPNTEEVHIYQAAADKWERVHVLQKHDQIVCGI
DWSSKMNKIVTVSHDRNSYVWNQEGGEWVPTLVILRLNRAALCVQWSPKENKFAVGSGAK
TVCICYYEQENNWWVSKLIRKRHNSSVTSVAWHPNNILLATTSTDGKCRVFSTFIKGVDT
RDGAGSSSDAKFGEQIIQLDLSYSWAFGVKWSPSGNTLAYVGHNSMIYFVDDVGPSPLAQ
SVAFRDLPLRDVLFVSEKMVVGVGFDCNPMIFAADESGLWSFIRFLGQRQTTPTSARAGS
QISGAFGKFYGQSKYNNADNDTSDARAHENCITCIVPLKKGRDSKVTHFSTSGLDGKVVI
WELGNQDIADYL
>Sgl82848 E3_activity/RING/RING 34.2 6.0
MKPHIRKLFPLQEDHNPTLFSSENNTHDSETHNNNSSSSSSTGCCYNNLKLNPPFDSAMA
LTVLVLLTALFFMGFFSIYIRRFADESSVDPTRRRRGGENPNPAARTTYRSMSAKGADPT
TVKALPVYAYCGGGAKQGIDEMECAICLSEFEEREWIKEIPYCGHVFHVECIDTWLASHV
TCPLCRTAKLLVERHVDGGDKEVHVKEGEVEEREVRLVVHGGDTWSNREVEEREVGPIRG
ERRSTSCLWCGDRVRLHRSLSF
>Sgl82854 E3_adaptor/Cullin_RING/DCX/DWD 19.2 3.5
MQMSPFPSQNGVDGDDERDDEEEYEDEDELSEELEEKEEEDEEPKLKYQRMGGSLSTLLS
NDAATCIAVSDRMIALGTHCGCLHILDFLGNQVKEFHAHKAAVNDLSFDLEGEFIGSCSD
DGSVVISSLFSDEKQKFEYHRPMKALALDPDYARKSLKRFVAGGLAGQLIYYTKKWFGYQ
EQVLHSGEGPIHAVAWRTSLIAWANDVGVKVYDTANDQRVTFVERPRGSPHPELLLPHLV
WQDDALLIIGWGTSVKIASLRGNQYGGANGSHKPVSTSIVRQVDIVASFQTNYYISGIAP
FGDSLAILAYIPGEEDGEKDFSSTAPPRQANAQRPEVRIVTWTNDELATDALPVHGFEHY
KAKDYCLSHTPLSGSNYTNGRWAAGDEPLYYVVSPKDIVIAKPRDAEDHINWLLEHGWYD
KALAEVEATQGRKELFEEVGSRYLEHLLAEKRYDEAAALCPKLLQGSGSAWERWIIRFAQ
LRQLPVLACYIPTENPKLSDTLYELALVALAMNPAHHKDFLSAVKSWPRSIYSAPTILSE
IEPQLRASMMSDNLKEALAELYVRTGQNEKAFSFFADLLKPDVFDFIERHSLHTAVREKV
VQLMILDTKRATTLLVQQRKVITPSDVVSQLLKAGDKCDFRYYLYLYLHALFEASPHAGR
DFHDMQVELYADYDSQMLFPFLRSSQHYTLEKAYEICVGKGLLKEKAFILGRMGNSKQAL
AVIINELGDMVEAVEFASMQNDDEIWEELIKQSTQNPEMVGMLLEHTVGNLDPLHIVNVV
PDGLEIPRLRDRLVKIITDYRTETSLRHGCNDILKADIVNLLVKYYKEARHAIYLSNEED
EARSKRDDNRTAESLTKAPSLRNMDLKSKTKAGGRCCMCFDPFSMLNVSVVVFFCCHAYH
MTCYMDSLNQFNDEKEAQNGFLDSDQDGYDDEENGERQSDSSRMRCILCTNAAR
>Sgl82856 E3_activity/RING/RING 43.2 6.2
MMRRYRDSPSYSRRESSSYRDGQLGWNPDFVSQDNQRYGAPAGYRPYDERPPIRPFGVPS
LPSDFYPATRVIIMSNSPGQRMSPRLLTPPSHGLTPRFNVPESMQVPTEIPRFNVPESMQ
VPGEIPRFNSPESMQEPTENNESKLTKQEQGNVLSKLKKEIYNPMPKILAKRVSLYYREL
NRDPNTKATEKHRDEDKKSCAVCLEDFEAKEEVMVTPCSHMFHEECIVPWVKNHGQCPVC
RANFIEKRQNQNALPFNNNSRSSSSNNNNNNNNNSRRQVVYQPAGQRVLFGDEILSLIQA
MDEAFPWRM
>Sgl82909 E3_activity/RING/RING 10.9 18.4
MVRDGEGCGGGGDWDVLGFEFGSMVEGDTGSSGTSFSSLPWWPWRNWNLNWNSRICQRHK
GRFPGLEEMTPVCPFVKAARPDDASSKRSGDSQCKHAAEHESKSKNESSDSSIIEPKCPL
GYDSRSFKIGPLSCVLCKALLFESSKCVPCSHLFCKACILRFKDCPLCGADIEKIEPDEE
LQKLVDKFIDGHARIKRSPVSTDVEEKIIDKPVIYEDVSLERGAFLVQQAMRAFRAQNVE
SAKSRLSICAVDIREQLKESGNKPELCSQLGAVLGMMGDCCRSMGDAGSAVTYFEESVEF
LSQVPTEDMEIIHTLSVSLNKIGDIKYYDGDLQASRAYYFRSLDVRRSALKNHCDSASLT
LDVAVSLAKVADVDRGLGNEEGAIAGFREAVNMLECLKIDSSQIALEQRRQSVLEFLNSQ
IAADKQSDQTE
>Sgl82921 UBD/UBC-like/UBD_UBC 170.5 0.0
MANSNLPRRIIKETQRLLSEPAPGISASPSEENMRYFNVMILGPSQSPYEGGVFKLELFL
PEEYPMAPPKVRFLTKIYHPNIDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPD
DPLSENIAKHWKSNEVEAVETAKEWTRLYATGA
>Sgl82929 E3_adaptor/Cullin_RING/SCF/F-box 17 0.1
MLALGFGYAYNMFDDLLVREKRVESFFEGGGRCGGPGAFECLTGGGYGAGVGWDEARHDQ
MVGRRCKRRRNMNQLHKQRKMVLLPDEIIVNEILPRLPVKALLRFKVVCKQWNTTISSES
FAKLQLYNKNPHDQNLLLINLNFATSDSVLYKLNHLETTENLTTNKYSSVNIYIWNPATR
QRHPIPFDVTQFHNLDYRDGLFGFGYVSATHEYKLIMGNLKGDWYVYCTTNNGSNESKCG
WRRCLHYYHPTPHEESVVLSKQVGVLVGEKLHWKGAYFVVCFDLASEKYSHIPIPRTTWG
EWVVSQPRSWSDSPWIQNKIRDRFDNSMLCKFGGCLSLCVIDEYVGTFNLWKFMDSPTSP
NAPNWSKVVTMWCDSGKYLSSRSGGNLLLNPYANTIQVADTGKFLVFTKDKTLLLCDPRR
NILNCYKLLALKKDGRITMVMDYVESLISPLHLL
>Sgl82932 E3_adaptor/Cullin_RING/SCF/F-box 13.2 0.0
MLEVVSKRPRPTDCMNDSSRKCRKRKKRKRGKMDKISELPEHLLHQILTRLHSKDAARTS
ILSKTWKEIWDSYQVLDFDLRCDYNVSDDLKELYKNQIYRLQRIQKLRLCFTKSTGLTID
DVYDWIGAAIDRGVRELEFQVKGIDNLSLPSRVMHGNSITALNLQGCNIRTYFINLPQLQ
KLSLKNLNIYPGDFEDLIAGCPYIEDLRLIQCAGLKKLSISNLDRLKRVDLHKCLLLRNV
VIKVQSLETFWYYSDKKKKNCEINIEECRALRELTVEYPRMTDEVFHGKIYELGELEKLV
LSRCNGLKSIALSGGKLRNLVIRRCRNLKEARCNTPNLTSLEYTGQRMPLLFTDLHKLNK
ALLSFDRSSTAAAKWKGGGDDASRLTSFLHQISYNNGLKSMSVNELDTVIYEDIRAMLLP
LHYISNPWAVQISLHFQDLLDTALKNSPFPSTLSIMSHVNSDFPEIIHRKLMKEKAAPQC
CGCFMNKCWRHYLKNVSIEKWILDTTELQKPSEFHDWKKSTFRLEWKC
>Sgl83234 E3_adaptor/Cullin_RING/DCX/DWD 38.5 0.9
MITESEGGQDICKRICVAGGDPTLVESPTEPKWTPEVFLGLGSLNETIISCGEDAIIRVW
DPVTGQEIMSTKDNKSGHKQAITSLSMSADKSQFLTGALDKSAKLWDTRTLTLIKTYVTE
RPVNAVTMSPLLDHSWNTRYIALGDGRNICLECMESAIMDTGDCQPLYHAIRDYYEGMNM
RIDQQIPMLLVERQALNEAIVGEKNNRSHCSSMAAGGTAAIGLRPMADMAMAAGQNRSHR
P
>Sgl83340 E3_adaptor/Cullin_RING/DCX/DWD 122.5 15.1
MQTSTCHYRSQWNDDSEHDLYDSRSASFSSLPSLPRVPVLTVQPNQQSHLATTLSHCVTT
LTGHSSNVFSLTLAGKYLYTGSSDNEIRVWKRNPFSYEAGDESLTNDNLVAVGKSAVKSL
VVLGNQLFSAHQDCKIRVWKIKTQEQAKNMRYEKQATLPTLGDRTKRLLNPNNQVEIRRH
KKCTWVHHVDTVSALAFSQDQSLLYSVSWDRTLKVWQTSDFKCLESVKNAHDDAINAVAV
SYDGDVYTGSADKKIKVWRKHSGNKKHTLATTLEKHKSGINALALSPDGLLLYSGACDRS
ILVWEKNDHYDSMELVGALRGHTKAILCLAAVDDLVFSGSADKTVRVWRRVGINYSCVAI
LEGHQGPVKCLTAAADSYSQHNNTVSSNYLIYSGSLDCDIRVWQVLVSK
>Sgl83352 E3_adaptor/Cullin_RING/SCF/F-box 16 0.0
MDSWSALPPDLLVSIAERLESRSHIINFRAVCQSWRSAVSTSLLTPTNILSSLFPYKGII
FNNNPSSILVASSVSLLQSSVNPKFEPWLVTVEEFNPGKLLIRAPLSRVVYRGLSSNTNL
DLSNINVLELGRFYTFRRVDKLEEMFSEKRLSEYDNKVVLFVNPNCETNNNPSIDDCTLI
ELYDQVDHLSVTRLKNGYKHQVSFKGREFDDVVNFNGRIYAVDFLGRLCYMEYDSLEMLS
VTESPLPGCSRSNYKKRLAVLDEELYVVYRRCQISDNEGGAFKVFKLNEAEEKWDELDGV
GDDKILFVTFDGCFFVSVKDIPGWKGNCIVFRRGSFPEYSGIRSFDCKIFESWHLHRDVA
VFYFQNGDCKPLVTCSGYSGIFTPPSWIFYERIKPNSSTR
>Sgl83353 E3_adaptor/Cullin_RING/SCF/F-box 16.8 0.0
MSRRKIFWSELPTEILSSIAERLKLRSDVLHFRAVCRTWRKSAPSSLLTGKKSLSPILPH
FFSIKPCNEAMNRGQWNFASNRLVLVANSVFLVHSIANPNFEPWLFSVEEFNPGKLYLRT
PLKRTVVEHMPKGFPTNLDFSRFRVSEISRMYSLSFDPSDSSVKIKNKKNRVSQCFDRVV
LHVNSDKCDADTVAIDDCTLMVLYYDSSVGSFGKISLRDRQFSVLECCSIKKFDDVVSFK
GKVLAIDRKGKLYEECNGMMSRITDVPETEGGLGIGLGGDRKKRLVKSCGELYLVYRCSW
REKVAFKVFKLEDDGKMMKWEQLKGIGDDRIIVATHDGCFFVPSKDIPSWPGNSLVFVRG
VFPAYDSIHKADLELFKSRNGPPSEIAIYNFGSGTCKVKVCNSPKVLWPPPAWLSSDPHL
PNSSHMDEEEEEEEEEEEKGSLVQNCRESSSINENTSTPEFQGDSQVECISPLDIQENLP
AEDAGALDITMQIQPNTTIYIDSTPTTTISDNAITECCNVISKSPESDVTKTKFQGVDVS
SDLIPTLKAIWAKHGNILEGNRVQSNVLVAWALESLAKMVILLQNTSGGSLDNSQVDYLS
STLCDLQLMQLNVDWLASSVAKVLKLQKAMTLRAEMKDTLSEIDKVKTLVTDFKLKFLAE
LSGLEQMLDEKRKMVHESLCDFNCLDSSSGFGEGLC
>Sgl83357 E3_activity/RBR 246.1 57.9
MMDIDYSESESDFDAVEGFTSGEPEVNYNILSESDIRRRQEEEINHTSAMLCLRDSESRL
LLCNYKWNVEKLHEEWFTDESLFVKSAAINDSGSGTLMLRCPGYKCGAAVTRDLVKDLCS
EEDVAKYDRYFFRSYVESKMEKVIKWCPAPGCEYAVEFMGDDCRFGYDVTCECSYSFCWN
CVEPLHRPADCEVVEKWLKKNNSEAENTKWILAFSKPCPKCKRPIEKNKGCNHMTCRAPC
WFQFCWLCRGDWYEHSRGGGSCNGYDTKIEDQDETMRKHAKHSLQRYSHYFERWASNNKS
QQKAMEDLRKVQTVDLKILSSNVTIPESQLAFLEEGWQQIIECRRVLKWTYAYGYYLEER
EPGKRQFFEYLQGQAENCLEKLHACAELELSPFLQEGPNQDPDLNFIQYRCKMVGLTKMT
GKHFEKLSKALENGLQEVVVPEGATTSTMIQETKKRNNNNNNNNNSISSSQLTVFRVPLV
PLRRTRHPVRHNSHADWMMISGSVTDVPSTSKLDDSNYDQDYYDNNENDDDNNEDEHTVA
DVQDYDSASTSNHKETYTVLKEGDILKRQELEISEVFSILSIPEVEVSKLLCKYKWNISR
LYDEWFKDEQKVREEVGLPNSKKLVKCGICFDDLHVQEIYPMACGHAYCRECWKCYITES
IDNGPGCLLLTCPEPSCGVAVCRDMIDDLVTEEKKKMYFHHFLRSYVEASKKIKWCPAPG
CENAVELELGNEKFDVTCLCSFTFCWNCGEEGHHPVKCDTVTKWLKKNSSGSETTNWIRD
NTKNCPNCNRSIEKKNRGCMHMTCPPPCNFQFCWLCLGDWKTHSSKTGGHFTCNIYEDGK
KEGLYEKKRRKNYKYGEEQSR