In eukaryotes, the nucleosome is the basic structural unit of chromatin, composed of an octamer of histones tightly wrapped by genomic DNA. To allow dynamic binding of transcription machinery to DNA, eukaryotes have evolved the Snf2 proteins as chromatin remodeling factors (CHRs), which can regulate the positioning of nucleosomes on chromatin and thus affect gene expression. Studies have shown that CHRs are involved in various processes such as development and stress response. With the increasing number of plant genomes being sequenced, there is a growing demand for predicting gene functions. Therefore, we predicted CHRs in various plant genomes, and constructed a database of plant chromatin remodeling factors named PlantCHRs.
PlantCHRs currently contains CHRs and chromatin remodeling complex members from 79 plant species. Users can access basic annotation information, physicochemical properties of proteins, protein domains, gene family information, and interacting protein information of these CHRs. In addition, we have developed an online tool for predicting CHRs and chromatin remodeling complex members in newly sequenced plant species using PlantCHRs. We hope that our database will contribute to the study of plant chromatin remodeling factors.
2023-05-03
PlantCHRs is online now!
Yan, et al. "PlantCHRs: a database of plant chromatin remodeling factors.